+F Repair protein KO
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DNA Repair and Recombination Proteins - Desulfosarcina alkanivorans
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DSCA_42580 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D DSCA_59530 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D DSCA_52850 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E DSCA_51180 hypothetical protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E DSCA_07900 smuG1; single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E DSCA_51640 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E DSCA_12910 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E DSCA_13180 ATP-dependent helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
E DSCA_02880 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E DSCA_03800 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D DSCA_04300 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_10380 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_14810 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_15000 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_30770 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DSCA_42580 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D DSCA_59530 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D DSCA_33740 methylated-DNA--protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D DSCA_52850 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D DSCA_58770 hypothetical protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E DSCA_07900 smuG1; single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E DSCA_00820 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E DSCA_42590 AraC family transcriptional regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E DSCA_51180 hypothetical protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E DSCA_51640 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E DSCA_02010 tag; DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E DSCA_05850 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E DSCA_12910 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E DSCA_12900 exoA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E DSCA_55860 nfo; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E DSCA_08680 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E DSCA_05090 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E DSCA_16690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E DSCA_44530 polA; DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E DSCA_47600 uvrA_1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E DSCA_65110 uvrA_2; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E DSCA_09310 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E DSCA_09320 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E DSCA_16560 pcrA; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DSCA_53290 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DSCA_44530 polA; DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E DSCA_16690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F DSCA_21490 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F DSCA_21480 hypothetical protein K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F DSCA_21190 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F DSCA_05250 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F DSCA_16570 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E DSCA_10910 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E DSCA_35010 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E DSCA_09530 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E DSCA_09520 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E DSCA_04970 dnaE; DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E DSCA_12960 DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E DSCA_41390 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E DSCA_01090 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E DSCA_59430 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E DSCA_09450 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DSCA_50570 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DSCA_57370 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E DSCA_63350 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E DSCA_16690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E DSCA_16560 pcrA; DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DSCA_53290 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DSCA_40380 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E DSCA_40520 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E DSCA_62850 hypothetical protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E DSCA_10690 recB; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E DSCA_10700 hypothetical protein K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E DSCA_02870 recD2_1; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E DSCA_03790 recD2_2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E DSCA_10680 recD; RecBCD enzyme subunit RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E DSCA_22100 recD2_3; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E DSCA_31250 hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E DSCA_04750 recA; protein RecA K03553 recA; recombination protein RecA
E DSCA_63620 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E DSCA_63630 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E DSCA_63610 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E DSCA_26970 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E DSCA_04750 recA; protein RecA K03553 recA; recombination protein RecA
E DSCA_27860 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E DSCA_05090 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E DSCA_16620 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E DSCA_63370 recR; recombination protein RecR K06187 recR; recombination protein RecR
E DSCA_44400 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E DSCA_41410 hypothetical protein K03554 rdgC; recombination associated protein RdgC
E DSCA_63620 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E DSCA_63630 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E DSCA_63610 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E DSCA_16020 cas1; CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E DSCA_02340 helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E DSCA_14350 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F DSCA_62020 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F DSCA_41380 acrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F DSCA_00680 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F DSCA_25680 transcriptional regulator K03530 hupB; DNA-binding protein HU-beta
F DSCA_27370 hbsU; DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F DSCA_58100 hup; transcriptional regulator K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F DSCA_05090 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F DSCA_16620 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F DSCA_63370 recR; recombination protein RecR K06187 recR; recombination protein RecR
F DSCA_16690 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F DSCA_01380 ihfA-1_1; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F DSCA_16530 ihfA-2_1; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F DSCA_20320 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F DSCA_22290 ihfA-2_2; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F DSCA_27730 ihfA-1_2; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F DSCA_10660 ihfB-1_1; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
F DSCA_25670 ihfB-1_2; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
F DSCA_59440 ihfB-1_3; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F DSCA_08440 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F DSCA_45110 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F DSCA_47600 uvrA_1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F DSCA_65110 uvrA_2; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F DSCA_09310 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D DSCA_12940 dinB_1; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D DSCA_20260 dinB_2; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D DSCA_56080 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D DSCA_04750 recA; protein RecA K03553 recA; recombination protein RecA
D DSCA_02990 lexA2; LexA repressor 2 K01356 lexA; repressor LexA [EC:3.4.21.88]
D DSCA_12920 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D DSCA_44400 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D DSCA_40380 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D DSCA_40520 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D DSCA_46670 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D DSCA_04300 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_10380 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_14810 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_15000 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D DSCA_30770 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D DSCA_56160 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D DSCA_58000 nrdJ; ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D DSCA_30820 phosphoesterase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024