+E Polyketide biosynthesis proteins KO
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Polyketide Biosynthesis Proteins - Dactylosporangium aurantiacum
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APolyketide synthase (PKS)
B Modular type I PKS
C cis-AT PKS
D Erythronolide PKS
D Oleandomycin synthase
D Pikromycin PKS
D Avermectin PKS
D Tylactone synthase
D Protomycinolide IV synthase
D Niddamycin PKS
D Rapamycin PKS
D Immunomycin PKS
D Ansamitocin PKS
D Rifamycin PKS
D Polyene macrolide PKS
D Pimaricinolide synthase
D Candicidin PKS
D Soraphen PKS
D Stigmatellin PKS
D Mycolactone PKS
D Coelimycin PKS
D Aureothin PKS
D Spectinabilin PKS
D Phthiocerol / Phenolphthiocerol PKS
C trans-AT PKS
D Bacillanene hybrid PKS-NRPS
D Chivosazol hybrid PKS-NRPS
E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133]
D Macrolactin PKS
D Difficidin PKS
D Rhizoxin hybrid PKS-NRPS
D Myxovirescin hybrid PKS-NRPS
E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932]
D Albicidin synthase, hybrid PKS-NRPS
E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516]
E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523]
D Etnangien PKS
E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193]
B Iterative type I PKS
C Fungal nonreducing PKS (NR-PKS)
C Fungal partially reducing PKS (PR-PKS)
C Fungal highly reducing PKS (HR-PKS)
C Fungal hybrid type
D Zearalenone synthase
D Asperfuranone NR/HR-PKS
E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2]
E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2]
C Bacterial type
B Type II PKS
C C9-C14 cyclized polyketide type
D Spore pigment PKS
C C7-C14 cyclized polyketide type
D Octaketide PKS
E Daura_28650 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_37850 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_28645 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_37855 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_28640 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein
E Daura_37920 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein
E Daura_28620 fabG; 3-oxoacyl-ACP reductase FabG K12420 actIII; ketoreductase [EC:1.1.1.-]
E Daura_28615 aromatase/cyclase K05554 actVII; aromatase [EC:4.2.1.-]
E Daura_32910 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-]
D Nonaketide PKS
E Daura_28650 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_37850 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_28645 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_37855 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_28640 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein
E Daura_37920 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein
E Daura_28620 fabG; 3-oxoacyl-ACP reductase FabG K12420 actIII; ketoreductase [EC:1.1.1.-]
E Daura_37900 cyclase family protein K14250 oxyN; cyclase
E Daura_28655 TcmI family type II polyketide cyclase K15926 jadI; cyclase
D Decaketide PKS
E Daura_28650 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_37850 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_28645 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_37855 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
E Daura_28640 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein
E Daura_37920 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein
E Daura_28620 fabG; 3-oxoacyl-ACP reductase FabG K12420 actIII; ketoreductase [EC:1.1.1.-]
E Daura_37900 cyclase family protein K14250 oxyN; cyclase
B Type III PKS
C Plant type
C Fungal type
C Bacterial type
D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550]
D ------ arsC; alkylpyrone synthase [AVN:Avin_29530]
B PKS-NRPS hybrid
C Bacterial type (modular)
D Myxalamid hybrid PKS-NRPS
D Myxothiazol hybrid PKS-NRPS
E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019]
D Coronatine hybrid PKS-NRPS
D Microcystin synthetase
D Epothilone synthetase
D Bleomycin synthetase
D Colibactin synthetase
C Fungal type (trans-ER, iterative)
D Aspyridone synthetase
C Fungal type (iterative)
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ANonribosomal peptide synthetase (NRPS)
B Linear NRPS
C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2]
C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500]
C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000]
C ACV synthetase
C Bacitracin synthetase
C Viomycin synthetase
C Pristinamycin I synthetase
C Tyrocidine synthetase
C Surfactin family lipopeptide synthetase
C Iturin family lipopeptide synthetase
C Fengycin family lipopeptide synthetase
C Arthrofactin type cyclic lipopeptide synthetase
C Vancomycin synthetase
C Nocardicin synthetase
D Daura_29845 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein
D Daura_30080 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein
D Daura_34415 MbtH family protein K05375 mbtH; MbtH protein
D Daura_16070 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein
D Daura_17695 MbtH family protein K05375 mbtH; MbtH protein
D Daura_18480 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein
C Bialaphos synthetase
C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase
B Iterative NRPS
C Enterobactin synthetase
C Bacillibactin synthetase
D Daura_20930 non-ribosomal peptide synthetase K04780 dhbF; glyine---[glycyl-carrier protein] ligase [EC:6.2.1.66]
C Gramicidin synthetase
B Nonlinear NRPS
C Yersiniabactin synthetase
C Pyochelin synthetase
C Mycobactin synthetase
C Vibriobactin synthetase
C Myxochelin synthetase
C Petrobacin synthetase
C Syringomycin synthetase
C Vanchrobactin synthetase
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APolyketide tailoring proteins
B Hydrolase
B Ketoreductase
B Oxygenase
C Daura_16905 epoxide hydrolase K21159 sgcF; epoxide hydrolase
C Daura_37895 FAD-dependent oxidoreductase K14252 oxyL; 6-methylpretetramide 4-monooxygenase / 4-hydroxy-6-methylpretetramide 12a-monooxygenase [EC:1.14.13.232 1.14.13.233]
C Daura_37815 FAD-dependent monooxygenase K14256 oxyS; anhydrotetracycline 6-monooxygenase / 5a,11a-dehydrotetracycline 5-monooxygenase [EC:1.14.13.38 1.14.13.234]
C Daura_37840 FAD-dependent monooxygenase K14256 oxyS; anhydrotetracycline 6-monooxygenase / 5a,11a-dehydrotetracycline 5-monooxygenase [EC:1.14.13.38 1.14.13.234]
B Methylase
C Daura_37880 hypothetical protein K14251 oxyF; C-methyltransferase [EC:2.1.1.-]
C Daura_37845 hypothetical protein K14255 oxyT; 4-amino-anhydrotetracycline N4-methyltransferase [EC:2.1.1.335]
B Glycosyltransferase
B Halogenase
C Daura_27000 NAD(P)/FAD-dependent oxidoreductase K14257 ctcP; tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
C Daura_37810 tryptophan 7-halogenase K14257 ctcP; tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
B beta-Branched incorporating proteins
B Others
C Daura_37945 dapC; succinyldiaminopimelate transaminase K14254 oxyQ; aminotransferase
C Daura_37940 PPOX class F420-dependent oxidoreductase K21301 oxyR; 5a,11a-dehydrotetracycline reductase [EC:1.3.98.4]
C Daura_37835 flavin reductase family protein K21297 ctcQ; flavin reductase (NADH) [EC:1.5.1.36]
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ANonribosomal peptide tailoring proteins
B Reductase
B Thioesterase
B Oxygenase
B Glycosyltransferase
B Aminotransferase
C Daura_12880 PLP-dependent aminotransferase family protein K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103]
B Others
C Daura_07780 aminotransferase class V-fold PLP-dependent enzyme K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17]
C Daura_12945 hppD; 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46]
C Daura_31180 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46]
C Daura_12875 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46]
C Daura_30070 aspartate/glutamate racemase family protein K01779 racD; aspartate racemase [EC:5.1.1.13]
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#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024