+E Replication protein KO
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DNA Replication Proteins - Dendrobium catenatum
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D 110104150 origin of replication complex subunit 1 K02603 ORC1; origin recognition complex subunit 1
D 110101575 origin of replication complex subunit 2 K02604 ORC2; origin recognition complex subunit 2
D 110115091 origin of replication complex subunit 3 K02605 ORC3; origin recognition complex subunit 3
D 110103408 origin of replication complex subunit 3 K02605 ORC3; origin recognition complex subunit 3
D 110100463 origin of replication complex subunit 4 isoform X1 K02606 ORC4; origin recognition complex subunit 4
D 110110342 origin of replication complex subunit 1 K02607 ORC5; origin recognition complex subunit 5
D 110103259 origin of replication complex subunit 1 K02607 ORC5; origin recognition complex subunit 5
D 110105101 origin of replication complex subunit 6 K02608 ORC6; origin recognition complex subunit 6
D 110091917 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 110104100 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 110099882 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 110099890 CDT1-like protein a, chloroplastic K10727 CDT1; chromatin licensing and DNA replication factor 1
D 110108821 cell division control protein 6 homolog isoform X1 K02213 CDC6; cell division control protein 6
D 110102205 DNA replication licensing factor MCM2 K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D 110093857 DNA replication licensing factor MCM3-like isoform X1 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D 110113591 DNA replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D 110105565 DNA replication licensing factor MCM5 K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D 110097093 DNA replication licensing factor MCM6 K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D 110102753 DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D 110092169 cyclin-A2-1-like isoform X1 K06627 CCNA; cyclin-A
D 110107066 LOW QUALITY PROTEIN: cyclin-A3-1-like K06627 CCNA; cyclin-A
D 110103887 cyclin-A1-4 K06627 CCNA; cyclin-A
D 110103583 LOW QUALITY PROTEIN: cyclin-A3-1 K06627 CCNA; cyclin-A
D 110096412 cyclin-A2-1 K06627 CCNA; cyclin-A
D 110103529 cell division control protein 2 homolog A K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D 110105257 probable serine/threonine-protein kinase cdc7 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
C GINS complex
D 110105769 DNA replication complex GINS protein PSF1 K10732 GINS1; GINS complex subunit 1
D 110100594 DNA replication complex GINS protein PSF2 K10733 GINS2; GINS complex subunit 2
D 110109745 DNA replication complex GINS protein PSF3-like K10734 GINS3; GINS complex subunit 3
D 110099478 DNA replication complex GINS protein SLD5 K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D 110097517 DNA topoisomerase 2-binding protein 1 isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 110113309 BRCT domain-containing protein At4g02110 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D 110094174 ATP-dependent DNA helicase Q-like 5 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D 110107625 cell division control protein 45 homolog K06628 CDC45; cell division control protein 45
D 110107167 cell division control protein 45 homolog K06628 CDC45; cell division control protein 45
D 110116013 probable DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D 110112055 probable DNA helicase MCM9 isoform X1 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D 110095813 protein MCM10 homolog K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D 110098665 DNA polymerase alpha catalytic subunit isoform X2 K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D 110104434 DNA polymerase alpha subunit B K02321 POLA2; DNA polymerase alpha subunit B
D 110114810 DNA primase small subunit isoform X1 K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D 110114564 probable DNA primase large subunit K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D 110113617 DNA polymerase epsilon catalytic subunit A isoform X1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D 110111724 DNA polymerase epsilon subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D 110094123 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C DNA polymerase delta complex
D 110095356 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D 110105872 DNA polymerase delta small subunit K02328 POLD2; DNA polymerase delta subunit 2
D 110097470 DNA polymerase delta small subunit-like K02328 POLD2; DNA polymerase delta subunit 2
D 110092892 DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3
D 110111817 DNA polymerase delta subunit 4-like K03505 POLD4; DNA polymerase delta subunit 4
D 110111850 uncharacterized protein LOC110111850 K03505 POLD4; DNA polymerase delta subunit 4
D 110096460 uncharacterized protein LOC110096460 K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
D 110092559 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
D 110105461 replication protein A 70 kDa DNA-binding subunit A K07466 RFA1; replication factor A1
D 110112593 replication protein A 70 kDa DNA-binding subunit B K07466 RFA1; replication factor A1
D 110098092 replication protein A 32 kDa subunit B K10739 RFA2; replication factor A2
D 110110138 replication protein A 32 kDa subunit A isoform X1 K10739 RFA2; replication factor A2
D 110100181 replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
C RFC (replication factor C)
D 110108173 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
D 110110673 LOW QUALITY PROTEIN: replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 110093745 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 110092734 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 110094297 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 110099406 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D 110095063 ribonuclease H2 subunit A isoform X2 K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D 110101373 ribonuclease H2 subunit B isoform X1 K10744 RNASEH2B; ribonuclease H2 subunit B
D 110116192 ribonuclease H2 subunit C K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D 110105895 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 110114155 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 110115887 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 110099535 DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D 110100878 flap endonuclease 1-A isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D 110098820 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D 110103592 DNA annealing helicase and endonuclease ZRANB3 isoform X1 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 110104314 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D 110096047 uncharacterized protein LOC110096047 isoform X1 K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D 110109593 DNA (cytosine-5)-methyltransferase 1B K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 110116471 DNA (cytosine-5)-methyltransferase CMT2 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 110093912 DNA (cytosine-5)-methyltransferase 1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 110101174 DNA (cytosine-5)-methyltransferase 1 isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 110099856 uncharacterized protein LOC110099856 K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
C Prevention of re-replication factors
D 110114574 G2/mitotic-specific cyclin S13-7 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 110097268 G2/mitotic-specific cyclin-2-like K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 110096329 cyclin-B1-1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 110114934 G2/mitotic-specific cyclin-2-like K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 110112667 putative cyclin-B3-1 K21777 CCNB; G2/mitotic-specific cyclin-B, other
D 110111243 cyclin-SDS-like K21777 CCNB; G2/mitotic-specific cyclin-B, other
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
E 110104030 CST complex subunit STN1 K23312 STN1; CST complex subunit STN1
E 110102518 CST complex subunit TEN1 K23313 TEN1; CST complex subunit TEN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D 110092187 telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E 110094344 putative H/ACA ribonucleoprotein complex subunit 1-like protein 1 K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E 110101958 H/ACA ribonucleoprotein complex subunit 2-like protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E 110108376 H/ACA ribonucleoprotein complex subunit 3-like protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E 110102056 H/ACA ribonucleoprotein complex subunit 4 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D 110092187 telomerase reverse transcriptase isoform X1 K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E 110095769 small nuclear ribonucleoprotein-associated protein B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 110099035 small nuclear ribonucleoprotein SmD1a K11087 SNRPD1; small nuclear ribonucleoprotein D1
E 110106941 small nuclear ribonucleoprotein Sm D2-like K11096 SNRPD2; small nuclear ribonucleoprotein D2
E 110098550 small nuclear ribonucleoprotein SmD3b K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 110112762 small nuclear ribonucleoprotein SmD3b K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 110100407 small nuclear ribonucleoprotein SmD3b-like K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 110095220 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 110111480 probable small nuclear ribonucleoprotein F isoform X1 K11098 SNRPF; small nuclear ribonucleoprotein F
E 110106768 probable small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D 110110673 LOW QUALITY PROTEIN: replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 110093745 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 110092734 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 110094297 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 110099406 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D 110111411 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
D 110105633 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D 110109260 nijmegen breakage syndrome 1 protein isoform X1 K10867 NBN; nibrin
C Other termination factors
D 110106501 serine/threonine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 110100837 ATP-dependent DNA helicase Q-like SIM K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
D 110105692 ATP-dependent DNA helicase Q-like 4A isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D 110105246 DNA repair endonuclease UVH1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D 110091984 poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D 110102767 poly [ADP-ribose] polymerase 2-A isoform X1 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D 110098262 PIN2/TERF1-interacting telomerase inhibitor 1 K11135 PINX1; Pin2-interacting protein X1
D 110114971 regulator of telomere elongation helicase 1 homolog K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D 110105763 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 110115965 transcription factor Pur-alpha 1 K21772 PURA; transcriptional activator protein Pur-alpha
D 110108397 transcription factor Pur-alpha 1 K21772 PURA; transcriptional activator protein Pur-alpha
D 110114793 telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
D 114578379 LOW QUALITY PROTEIN: replication stress response regulator SDE2-like K25059 SDE2; replication stress response regulator SDE2
D 110111046 protein RTF2 homolog K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C 110099459 DNA topoisomerase 1 beta K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C 110114510 DNA topoisomerase 2 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 110107676 DNA topoisomerase 2 K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C 110100998 DNA topoisomerase 3-beta isoform X2 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C 110092904 DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D 110110050 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
D Other elongation factors
E 110106989 DNA polymerase I A, chloroplastic K02335 polA; DNA polymerase I [EC:2.7.7.7]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
D RFC (replication factor C)
D Other elongation factors
E 110099535 DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E 110100878 flap endonuclease 1-A isoform X1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 110104314 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
C 110112466 DNA gyrase subunit A, chloroplastic/mitochondrial K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C 110103757 DNA gyrase subunit B, chloroplastic/mitochondrial-like isoform X1 K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C 110099467 DNA topoisomerase 6 subunit B isoform X1 K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022