+D GENES KO
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KEGG Orthology (KO) - Candidatus Doolittlea endobia
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:den00010]
D MHIR_DE00085 glk; Glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D MHIR_DE00549 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D MHIR_DE00543 fbaA; Fructose-bisphosphate aldolase class 2 K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D MHIR_DE00310 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D MHIR_DE00407 gapA_1; Glyceraldehyde-3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D MHIR_DE00544 pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D MHIR_DE00560 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D MHIR_DE00154 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MHIR_DE00337 pykA; Pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D MHIR_DE00226 aceE; Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D MHIR_DE00225 aceF; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00020 Citrate cycle (TCA cycle) [PATH:den00020]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MHIR_DE00226 aceE; Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D MHIR_DE00225 aceF; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:den00030]
D MHIR_DE00549 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D MHIR_DE00012 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D MHIR_DE00263 pgl; 6-phosphogluconolactonase K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31]
D MHIR_DE00640 gnd; 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D MHIR_DE00633 rpe; Ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D MHIR_DE00201 tktA; Transketolase 1 K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D MHIR_DE00302 prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D MHIR_DE00543 fbaA; Fructose-bisphosphate aldolase class 2 K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C 00040 Pentose and glucuronate interconversions
D MHIR_DE00633 rpe; Ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:den00051]
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D MHIR_DE00543 fbaA; Fructose-bisphosphate aldolase class 2 K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D MHIR_DE00310 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:den00052]
D MHIR_DE00085 glk; Glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism [PATH:den00500]
D MHIR_DE00085 glk; Glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D MHIR_DE00549 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:den00520]
D MHIR_DE00033 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D MHIR_DE00245 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D MHIR_DE00085 glk; Glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D MHIR_DE00549 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00620 Pyruvate metabolism [PATH:den00620]
D MHIR_DE00226 aceE; Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D MHIR_DE00225 aceF; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MHIR_DE00510 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D MHIR_DE00511 pta; Phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D MHIR_DE00337 pykA; Pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D MHIR_DE00704 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D MHIR_DE00187 accB_1; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D MHIR_DE00316 accC; Biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D MHIR_DE00477 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:den00630]
D MHIR_DE00168 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:den00640]
D MHIR_DE00510 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D MHIR_DE00511 pta; Phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MHIR_DE00704 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D MHIR_DE00187 accB_1; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D MHIR_DE00316 accC; Biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D MHIR_DE00477 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
C 00650 Butanoate metabolism
C 00660 C5-Branched dibasic acid metabolism
C 00562 Inositol phosphate metabolism [PATH:den00562]
D MHIR_DE00006 suhB; Inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D MHIR_DE00310 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:den00190]
D MHIR_DE00488 ndhC; NAD(P)H-quinone oxidoreductase subunit 3 K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D MHIR_DE00489 nuoB; NADH-quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D MHIR_DE00490 nuoC; NADH-quinone oxidoreductase subunit C/D K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D MHIR_DE00491 nuoE; NADH-quinone oxidoreductase subunit E K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D MHIR_DE00492 nuoF; NADH-quinone oxidoreductase subunit F K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D MHIR_DE00493 nuoG; NADH-quinone oxidoreductase subunit G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D MHIR_DE00494 nuoH; NADH-quinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D MHIR_DE00495 nuoI; NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D MHIR_DE00496 nuoJ; NADH-quinone oxidoreductase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D MHIR_DE00497 nuoK; NADH-quinone oxidoreductase subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D MHIR_DE00498 nuoL; NADH-quinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D MHIR_DE00499 nuoM; NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D MHIR_DE00500 nuoN; NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D MHIR_DE00406 cydA; Cytochrome bd-I ubiquinol oxidase subunit 1 K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D MHIR_DE00405 cydB; Cytochrome bd-I ubiquinol oxidase subunit 2 K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D MHIR_DE00404 cydX; Cytochrome bd-I ubiquinol oxidase subunit X K00424 cydX; cytochrome bd-I ubiquinol oxidase subunit X [EC:7.1.1.7]
D MHIR_DE00531 atpH; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D MHIR_DE00537 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D MHIR_DE00593 ppa; Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:den00710]
D MHIR_DE00544 pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D MHIR_DE00407 gapA_1; Glyceraldehyde-3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D MHIR_DE00543 fbaA; Fructose-bisphosphate aldolase class 2 K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D MHIR_DE00201 tktA; Transketolase 1 K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D MHIR_DE00310 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D MHIR_DE00633 rpe; Ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00720 Other carbon fixation pathways [PATH:den00720]
D MHIR_DE00704 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D MHIR_DE00187 accB_1; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D MHIR_DE00316 accC; Biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D MHIR_DE00477 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D MHIR_DE00617 folD; Bifunctional protein FolD protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D MHIR_DE00511 pta; Phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D MHIR_DE00510 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00680 Methane metabolism [PATH:den00680]
D MHIR_DE00168 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MHIR_DE00154 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MHIR_DE00543 fbaA; Fructose-bisphosphate aldolase class 2 K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D MHIR_DE00510 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D MHIR_DE00511 pta; Phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D MHIR_DE00560 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 00910 Nitrogen metabolism
C 00920 Sulfur metabolism
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:den00061]
D MHIR_DE00704 accA; Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D MHIR_DE00187 accB_1; Biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D MHIR_DE00316 accC; Biotin carboxylase K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D MHIR_DE00477 accD; Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D MHIR_DE00220 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein
D MHIR_DE00218 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D MHIR_DE00217 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D MHIR_DE00628 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase 1 K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
D MHIR_DE00219 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D MHIR_DE00340 fabA; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14]
D MHIR_DE00700 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D MHIR_DE00008 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis [PATH:den00074]
D MHIR_DE00637 acpS; Holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D MHIR_DE00220 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein
D MHIR_DE00218 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:den00561]
D MHIR_DE00447 plsB; Glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
D MHIR_DE00144 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:den00564]
D MHIR_DE00447 plsB; Glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
D MHIR_DE00144 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D MHIR_DE00696 cdsA; Phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D MHIR_DE00041 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K00998 pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D MHIR_DE00457 psd; Phosphatidylserine decarboxylase proenzyme K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D MHIR_DE00551 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D MHIR_DE00139 pgpA; Phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
D MHIR_DE00351 pgpB; Phosphatidylglycerophosphatase B K01096 pgpB; phosphatidylglycerophosphatase B [EC:3.1.3.27 3.6.1.75 3.1.3.4 3.6.1.27]
D MHIR_DE00599 cls; Cardiolipin synthase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:den00230]
D MHIR_DE00302 prs; Ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D MHIR_DE00623 purE; N5-carboxyaminoimidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D MHIR_DE00188 gmk; Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D MHIR_DE00418 nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MHIR_DE00419 nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D MHIR_DE00190 spoT; Bifunctional (p)ppGpp synthase/hydrolase SpoT K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D MHIR_DE00596 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00240 Pyrimidine metabolism [PATH:den00240]
D MHIR_DE00327 carB; Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MHIR_DE00326 carA; Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D MHIR_DE00694 pyrH; Uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D MHIR_DE00153 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D MHIR_DE00684 cmk; Cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D MHIR_DE00513 dcd; Deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D MHIR_DE00418 nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MHIR_DE00419 nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D MHIR_DE00455 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D MHIR_DE00627 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MHIR_DE00431 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism
D MHIR_DE00327 carB; Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MHIR_DE00326 carA; Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
C 00260 Glycine, serine and threonine metabolism [PATH:den00260]
D MHIR_DE00168 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MHIR_DE00560 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MHIR_DE00041 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K00998 pssA; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D MHIR_DE00320 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D MHIR_DE00321 trpB; Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism
C 00280 Valine, leucine and isoleucine degradation [PATH:den00280]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00290 Valine, leucine and isoleucine biosynthesis
C 00300 Lysine biosynthesis [PATH:den00300]
D MHIR_DE00652 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D MHIR_DE00115 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D MHIR_DE00116 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00220 Arginine biosynthesis
D MHIR_DE00327 carB; Carbamoyl-phosphate synthase large chain K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D MHIR_DE00326 carA; Carbamoyl-phosphate synthase small chain K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
C 00330 Arginine and proline metabolism
D MHIR_DE00253 speG; Spermidine N(1)-acetyltransferase K00657 speG; diamine N-acetyltransferase [EC:2.3.1.57]
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism
C 00360 Phenylalanine metabolism
C 00380 Tryptophan metabolism
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:den00400]
D MHIR_DE00186 aroQ_1; 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D MHIR_DE00317 aroQ_2; 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D MHIR_DE00632 aroK; Shikimate kinase 1 K00891 aroK; shikimate kinase [EC:2.7.1.71]
D MHIR_DE00325 trpE; Anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D MHIR_DE00324 trpG; Anthranilate synthase component 2 K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D MHIR_DE00323 trpGD; Bifunctional protein TrpGD K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D MHIR_DE00322 trpC; Tryptophan biosynthesis protein TrpCF K13498 trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24]
D MHIR_DE00320 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D MHIR_DE00321 trpB; Tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
D MHIR_DE00354 panC; Pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
C 00430 Taurine and hypotaurine metabolism [PATH:den00430]
D MHIR_DE00511 pta; Phosphate acetyltransferase K13788 pta; phosphate acetyltransferase [EC:2.3.1.8]
D MHIR_DE00510 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:den00450]
D MHIR_DE00426 sufS; Cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D MHIR_DE00600 trxB; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D MHIR_DE00052 metG_1; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D MHIR_DE00168 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:den00470]
D MHIR_DE00264 ddlA; D-alanine--D-alanine ligase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D MHIR_DE00118 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
C 00480 Glutathione metabolism [PATH:den00480]
D MHIR_DE00640 gnd; 6-phosphogluconate dehydrogenase, decarboxylating K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D MHIR_DE00012 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis [PATH:den00540]
D MHIR_DE00701 lpxA; Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D MHIR_DE00124 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D MHIR_DE00699 lpxD; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D MHIR_DE00620 lpxH; UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D MHIR_DE00702 lpxB; Lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D MHIR_DE00314 lpxK; Tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D MHIR_DE00018 kdsD; Arabinose 5-phosphate isomerase KdsD K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
D MHIR_DE00420 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D MHIR_DE00483 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D MHIR_DE00601 waaA; 3-deoxy-D-manno-octulosonic acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D MHIR_DE00602 htrB; Lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis [PATH:den00550]
D MHIR_DE00033 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D MHIR_DE00245 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D MHIR_DE00121 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D MHIR_DE00118 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D MHIR_DE00115 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D MHIR_DE00264 ddlA; D-alanine--D-alanine ligase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D MHIR_DE00116 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D MHIR_DE00695 ispU; Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D MHIR_DE00117 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D MHIR_DE00120 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D MHIR_DE00650 mrcB; Penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]
D MHIR_DE00059 spoVD; Stage V sporulation protein D K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:den00730]
D MHIR_DE00174 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D MHIR_DE00070 thiI; tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MHIR_DE00596 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:den00740]
D MHIR_DE00137 ribE; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D MHIR_DE00517 ribC; Riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D MHIR_DE00135 ribF; Riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
C 00750 Vitamin B6 metabolism
C 00760 Nicotinate and nicotinamide metabolism
C 00770 Pantothenate and CoA biosynthesis [PATH:den00770]
D MHIR_DE00355 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D MHIR_DE00354 panC; Pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D MHIR_DE00637 acpS; Holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
C 00780 Biotin metabolism [PATH:den00780]
D MHIR_DE00628 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase 1 K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
D MHIR_DE00219 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D MHIR_DE00700 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D MHIR_DE00008 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D MHIR_DE00244 birA; Bifunctional ligase/repressor BirA K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:den00785]
D MHIR_DE00515 lipB; Octanoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D MHIR_DE00516 lipA; Lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MHIR_DE00226 aceE; Pyruvate dehydrogenase E1 component K00163 aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1]
D MHIR_DE00225 aceF; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00790 Folate biosynthesis [PATH:den00790]
D MHIR_DE00328 folA; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
C 00670 One carbon pool by folate [PATH:den00670]
D MHIR_DE00328 folA; Dihydrofolate reductase K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D MHIR_DE00617 folD; Bifunctional protein FolD protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D MHIR_DE00168 glyA; Serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D MHIR_DE00177 fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D MHIR_DE00431 thyA; Thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:den00860]
D MHIR_DE00284 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MHIR_DE00542 hemG; Protoporphyrinogen IX dehydrogenase [menaquinone] K00230 hemG; menaquinone-dependent protoporphyrinogen oxidase [EC:1.3.5.3]
D MHIR_DE00597 hemH; Ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:den00900]
D MHIR_DE00247 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
D MHIR_DE00068 ispA; Farnesyl diphosphate synthase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D MHIR_DE00695 ispU; Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D MHIR_DE00201 tktA; Transketolase 1 K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis
D MHIR_DE00652 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:den00521]
D MHIR_DE00085 glk; Glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
D MHIR_DE00006 suhB; Inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D MHIR_DE00085 glk; Glucokinase K00845 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D MHIR_DE00325 trpE; Anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D MHIR_DE00324 trpG; Anthranilate synthase component 2 K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D MHIR_DE00218 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D MHIR_DE00219 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D MHIR_DE00008 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D MHIR_DE00220 acpP; Acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:den03020]
D MHIR_DE00378 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D MHIR_DE00377 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D MHIR_DE00562 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D MHIR_DE00189 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:den03010]
D MHIR_DE00683 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D MHIR_DE00691 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D MHIR_DE00582 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D MHIR_DE00563 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D MHIR_DE00571 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D MHIR_DE00249 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D MHIR_DE00642 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D MHIR_DE00574 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D MHIR_DE00037 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D MHIR_DE00589 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D MHIR_DE00564 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D MHIR_DE00643 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D MHIR_DE00565 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D MHIR_DE00575 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D MHIR_DE00669 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D MHIR_DE00026 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D MHIR_DE00579 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D MHIR_DE00251 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D MHIR_DE00584 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D MHIR_DE00136 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D MHIR_DE00624 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D MHIR_DE00381 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D MHIR_DE00585 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D MHIR_DE00588 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D MHIR_DE00587 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D MHIR_DE00576 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D MHIR_DE00573 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D MHIR_DE00379 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D MHIR_DE00252 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D MHIR_DE00380 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D MHIR_DE00382 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D MHIR_DE00036 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D MHIR_DE00578 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D MHIR_DE00569 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D MHIR_DE00581 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D MHIR_DE00561 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D MHIR_DE00572 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D MHIR_DE00029 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D MHIR_DE00048 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D MHIR_DE00246 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D MHIR_DE00583 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D MHIR_DE00586 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D MHIR_DE00577 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D MHIR_DE00605 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D MHIR_DE00598 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D MHIR_DE00089 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D MHIR_DE00580 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D MHIR_DE00570 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D MHIR_DE00161 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D MHIR_DE00215 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D MHIR_DE00088 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D MHIR_DE00270 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D MHIR_DE00049 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D MHIR_DE00567 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D MHIR_DE00408 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D MHIR_DE00443 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D MHIR_DE00442 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:den00970]
D MHIR_DE00285 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MHIR_DE00294 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MHIR_DE00356 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00191 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00306 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00616 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00055 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D MHIR_DE00441 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D MHIR_DE00429 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D MHIR_DE00399 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D MHIR_DE00444 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D MHIR_DE00388 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MHIR_DE00456 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MHIR_DE00307 tRNA-His K14226 tRNA-His; tRNA His
D MHIR_DE00409 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D MHIR_DE00280 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00343 tRNA-Ser K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00400 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00430 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00468 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00282 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D MHIR_DE00711 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D MHIR_DE00487 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00281 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00398 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00467 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00653 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D MHIR_DE00221 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MHIR_DE00255 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MHIR_DE00308 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MHIR_DE00030 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00192 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00369 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00609 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00387 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MHIR_DE00390 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MHIR_DE00594 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MHIR_DE00410 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D MHIR_DE00389 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D MHIR_DE00283 tRNA-Val K14237 tRNA-Val; tRNA Val
D MHIR_DE00149 tRNA-Val K14237 tRNA-Val; tRNA Val
D MHIR_DE00284 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MHIR_DE00481 glnS; Glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D MHIR_DE00194 alaS; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MHIR_DE00501 aspS; Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D MHIR_DE00630 asnS; Asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D MHIR_DE00376 glyQ_1; Glycine--tRNA ligase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D MHIR_DE00397 glyS; Glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D MHIR_DE00051 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MHIR_DE00465 serS; Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MHIR_DE00618 cysS; Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D MHIR_DE00052 metG_1; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MHIR_DE00177 fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D MHIR_DE00393 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MHIR_DE00063 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MHIR_DE00134 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MHIR_DE00195 lysS; Lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D MHIR_DE00371 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MHIR_DE00132 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MHIR_DE00299 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MHIR_DE00047 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MHIR_DE00046 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MHIR_DE00146 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MHIR_DE00635 trpS; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:den03060]
D MHIR_DE00568 secY; Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MHIR_DE00384 secE; Protein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D MHIR_DE00469 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D MHIR_DE00159 secD; Protein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D MHIR_DE00160 secF; Protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D MHIR_DE00158 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D MHIR_DE00268 yidC; Membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D MHIR_DE00127 secA; Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D MHIR_DE00415 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D MHIR_DE00025 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D MHIR_DE00254 Bacteria_small_SRP K01983 ffs; SRP RNA
D MHIR_DE00506 ftsY; Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D MHIR_DE00002 lepB; Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D MHIR_DE00133 lspA; Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:den04122]
D MHIR_DE00174 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D MHIR_DE00509 tusA; Sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D MHIR_DE00644 tusB; Protein TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D MHIR_DE00645 dsrF; Intracellular sulfur oxidation protein DsrF K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D MHIR_DE00370 tusD; Sulfurtransferase TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D MHIR_DE00319 tusE; Sulfurtransferase TusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D MHIR_DE00095 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D MHIR_DE00070 thiI; tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
C 03050 Proteasome
C 03018 RNA degradation [PATH:den03018]
D MHIR_DE00452 rppH; RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D MHIR_DE00210 rne; Ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D MHIR_DE00154 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MHIR_DE00667 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D MHIR_DE00235 rnr; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D MHIR_DE00666 deaD; ATP-dependent RNA helicase DeaD K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D MHIR_DE00274 rho; Transcription termination factor Rho K03628 rho; transcription termination factor Rho
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D MHIR_DE00373 dnaK; Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D MHIR_DE00412 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D MHIR_DE00238 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D MHIR_DE00647 pcnB; Poly(A) polymerase I precursor K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:den03030]
D MHIR_DE00042 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D MHIR_DE00703 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D MHIR_DE00227 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D MHIR_DE00454 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D MHIR_DE00061 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D MHIR_DE00611 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D MHIR_DE00347 dnaB; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D MHIR_DE00625 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D MHIR_DE00348 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MHIR_DE00043 rnhA; Ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D MHIR_DE00659 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:den03410]
D MHIR_DE00677 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D MHIR_DE00147 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D MHIR_DE00655 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D MHIR_DE00197 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MHIR_DE00659 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:den03420]
D MHIR_DE00521 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D MHIR_DE00439 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D MHIR_DE00659 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:den03430]
D MHIR_DE00072 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D MHIR_DE00439 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D MHIR_DE00073 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D MHIR_DE00069 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D MHIR_DE00197 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MHIR_DE00348 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MHIR_DE00703 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D MHIR_DE00611 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D MHIR_DE00227 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D MHIR_DE00061 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D MHIR_DE00454 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D MHIR_DE00042 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D MHIR_DE00659 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:den03440]
D MHIR_DE00197 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MHIR_DE00348 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MHIR_DE00475 recA; Protein RecA K03553 recA; recombination protein RecA
D MHIR_DE00363 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D MHIR_DE00364 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D MHIR_DE00362 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D MHIR_DE00464 recB; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D MHIR_DE00463 recC; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
D MHIR_DE00707 recD2_2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D MHIR_DE00703 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D MHIR_DE00611 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D MHIR_DE00227 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D MHIR_DE00061 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D MHIR_DE00454 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D MHIR_DE00042 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D MHIR_DE00162 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D MHIR_DE00250 priB; Primosomal replication protein n K02686 priB; primosomal replication protein N
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:den02010]
D MHIR_DE00022 mlaC; putative phospholipid-binding protein MlaC precursor K07323 mlaC; phospholipid transport system substrate-binding protein
D MHIR_DE00021 mlaD; putative phospholipid ABC transporter-binding protein MlaD K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D MHIR_DE00020 mlaE; putative phospholipid ABC transporter permease protein MlaE K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D MHIR_DE00023 mlaB; putative phospholipid ABC transporter-binding protein MlaB K07122 mlaB; phospholipid transport system transporter-binding protein
D MHIR_DE00019 mlaF; putative phospholipid import ATP-binding protein MlaF K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D MHIR_DE00518 lolE; Lipoprotein-releasing system transmembrane protein LolE K09808 lolC_E; lipoprotein-releasing system permease protein
D MHIR_DE00520 lolC; Lipoprotein-releasing system transmembrane protein LolC K09808 lolC_E; lipoprotein-releasing system permease protein
D MHIR_DE00519 lolD; Lipoprotein-releasing system ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D MHIR_DE00395 lptF; Lipopolysaccharide export system permease protein LptF K07091 lptF; lipopolysaccharide export system permease protein
D MHIR_DE00396 lptG; Lipopolysaccharide export system permease protein LptG K11720 lptG; lipopolysaccharide export system permease protein
D MHIR_DE00014 lptB; Lipopolysaccharide export system ATP-binding protein LptB K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D MHIR_DE00313 msbA; Lipid A export ATP-binding/permease protein MsbA K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D MHIR_DE00260 yheH; putative multidrug resistance ABC transporter ATP-binding/permease protein YheH K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D MHIR_DE00261 cydD; ATP-binding/permease protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
C 02060 Phosphotransferase system (PTS)
D MHIR_DE00722 ptsN; Nitrogen regulatory protein K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
C 03070 Bacterial secretion system [PATH:den03070]
D MHIR_DE00159 secD; Protein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D MHIR_DE00160 secF; Protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D MHIR_DE00384 secE; Protein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D MHIR_DE00469 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D MHIR_DE00568 secY; Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MHIR_DE00158 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D MHIR_DE00268 yidC; Membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D MHIR_DE00127 secA; Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D MHIR_DE00506 ftsY; Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D MHIR_DE00415 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D MHIR_DE00025 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:den02020]
D MHIR_DE00099 phoQ; Virulence sensor histidine kinase PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
D MHIR_DE00098 phoP_1; Virulence transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
D MHIR_DE00031 ompC; Outer membrane protein C precursor K09475 ompC; outer membrane pore protein C
D MHIR_DE00336 phoP_2; Alkaline phosphatase synthesis transcriptional regulatory protein PhoP K07662 cpxR; two-component system, OmpR family, response regulator CpxR
D MHIR_DE00612 dnaA; Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D MHIR_DE00406 cydA; Cytochrome bd-I ubiquinol oxidase subunit 1 K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D MHIR_DE00405 cydB; Cytochrome bd-I ubiquinol oxidase subunit 2 K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D MHIR_DE00404 cydX; Cytochrome bd-I ubiquinol oxidase subunit X K00424 cydX; cytochrome bd-I ubiquinol oxidase subunit X [EC:7.1.1.7]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:den02024]
D MHIR_DE00238 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D MHIR_DE00325 trpE; Anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D MHIR_DE00324 trpG; Anthranilate synthase component 2 K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D MHIR_DE00440 zur; Zinc uptake regulation protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
D MHIR_DE00268 yidC; Membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D MHIR_DE00384 secE; Protein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D MHIR_DE00469 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D MHIR_DE00568 secY; Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MHIR_DE00158 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D MHIR_DE00127 secA; Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D MHIR_DE00506 ftsY; Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D MHIR_DE00415 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D MHIR_DE00025 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D MHIR_DE00626 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D MHIR_DE00154 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:den01501]
D MHIR_DE00031 ompC; Outer membrane protein C precursor K09475 ompC; outer membrane pore protein C
D MHIR_DE00059 spoVD; Stage V sporulation protein D K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:den01502]
D MHIR_DE00264 ddlA; D-alanine--D-alanine ligase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D MHIR_DE00116 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D MHIR_DE00117 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D MHIR_DE00120 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:den01503]
D MHIR_DE00099 phoQ; Virulence sensor histidine kinase PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
D MHIR_DE00098 phoP_1; Virulence transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
D MHIR_DE00336 phoP_2; Alkaline phosphatase synthesis transcriptional regulatory protein PhoP K07662 cpxR; two-component system, OmpR family, response regulator CpxR
D MHIR_DE00242 amiB; N-acetylmuramoyl-L-alanine amidase AmiB precursor K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D MHIR_DE00701 lpxA; Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:den01000]
C 01001 Protein kinases [BR:den01001]
D MHIR_DE00099 phoQ; Virulence sensor histidine kinase PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:den01009]
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C 01002 Peptidases and inhibitors [BR:den01002]
D MHIR_DE00133 lspA; Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D MHIR_DE00071 yajL; Chaperone protein YajL K03152 thiJ; protein deglycase [EC:3.5.1.124]
D MHIR_DE00658 ybiS; putative L,D-transpeptidase YbiS precursor K19235 ybiS; L,D-transpeptidase YbiS
D MHIR_DE00064 prlC; Oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70]
D MHIR_DE00446 mepM; Murein DD-endopeptidase MepM K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]
D MHIR_DE00688 map; Methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D MHIR_DE00182 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D MHIR_DE00129 htpX; Protease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D MHIR_DE00034 degQ; Periplasmic pH-dependent serine endoprotease DegQ precursor K04772 degQ; serine protease DegQ [EC:3.4.21.-]
D MHIR_DE00105 clpP; ATP-dependent Clp protease proteolytic subunit precursor K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D MHIR_DE00107 lon; Lon protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D MHIR_DE00341 lon1; Lon protease 1 K04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-]
D MHIR_DE00448 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MHIR_DE00002 lepB; Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D MHIR_DE00199 sppA; Protease 4 K04773 sppA; protease IV [EC:3.4.21.-]
D MHIR_DE00155 pmbA; peptidase PmbA K03592 pmbA; PmbA protein
D MHIR_DE00293 tldD; protease TldD K03568 tldD; TldD protein
D MHIR_DE00236 hflC; Modulator of FtsH protease HflC K04087 hflC; modulator of FtsH protease HflC
D MHIR_DE00237 hflK; Modulator of FtsH protease HflK K04088 hflK; modulator of FtsH protease HflK
C 01003 Glycosyltransferases [BR:den01003]
D MHIR_DE00650 mrcB; Penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:den01005]
D MHIR_DE00701 lpxA; Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase K00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]
D MHIR_DE00702 lpxB; Lipid-A-disaccharide synthase K00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]
D MHIR_DE00124 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase K02535 lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]
D MHIR_DE00699 lpxD; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase K02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]
D MHIR_DE00620 lpxH; UDP-2,3-diacylglucosamine hydrolase K03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]
D MHIR_DE00314 lpxK; Tetraacyldisaccharide 4'-kinase K00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]
D MHIR_DE00602 htrB; Lipid A biosynthesis lauroyl acyltransferase K02517 lpxL; Kdo2-lipid IVA lauroyltransferase/acyltransferase [EC:2.3.1.241 2.3.1.-]
D MHIR_DE00601 waaA; 3-deoxy-D-manno-octulosonic acid transferase K02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]
D MHIR_DE00420 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase K01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]
D MHIR_DE00483 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase K00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]
D MHIR_DE00018 kdsD; Arabinose 5-phosphate isomerase KdsD K06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:den01011]
D MHIR_DE00033 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D MHIR_DE00245 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D MHIR_DE00121 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D MHIR_DE00118 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D MHIR_DE00115 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D MHIR_DE00264 ddlA; D-alanine--D-alanine ligase A K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D MHIR_DE00117 mraY; Phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D MHIR_DE00120 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D MHIR_DE00204 murJ; putative peptidoglycan biosynthesis protein MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D MHIR_DE00650 mrcB; Penicillin-binding protein 1B K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]
D MHIR_DE00059 spoVD; Stage V sporulation protein D K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D MHIR_DE00658 ybiS; putative L,D-transpeptidase YbiS precursor K19235 ybiS; L,D-transpeptidase YbiS
D MHIR_DE00446 mepM; Murein DD-endopeptidase MepM K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]
D MHIR_DE00242 amiB; N-acetylmuramoyl-L-alanine amidase AmiB precursor K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D MHIR_DE00318 amiD; N-acetylmuramoyl-L-alanine amidase AmiD precursor K11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D MHIR_DE00428 lpp; Major outer membrane lipoprotein Lpp precursor K06078 lpp; murein lipoprotein
C 01004 Lipid biosynthesis proteins [BR:den01004]
D MHIR_DE00218 fabD; Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D MHIR_DE00217 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D MHIR_DE00628 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase 1 K00647 fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]
D MHIR_DE00219 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase FabG K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D MHIR_DE00340 fabA; 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase K01716 fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14]
D MHIR_DE00700 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D MHIR_DE00008 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D MHIR_DE00447 plsB; Glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
D MHIR_DE00144 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:den01006]
D MHIR_DE00068 ispA; Farnesyl diphosphate synthase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D MHIR_DE00695 ispU; Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D MHIR_DE00239 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
C 01007 Amino acid related enzymes [BR:den01007]
D MHIR_DE00284 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MHIR_DE00481 glnS; Glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D MHIR_DE00146 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MHIR_DE00635 trpS; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D MHIR_DE00618 cysS; Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D MHIR_DE00371 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MHIR_DE00052 metG_1; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MHIR_DE00134 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MHIR_DE00393 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MHIR_DE00063 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MHIR_DE00195 lysS; Lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D MHIR_DE00501 aspS; Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D MHIR_DE00630 asnS; Asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D MHIR_DE00299 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MHIR_DE00376 glyQ_1; Glycine--tRNA ligase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D MHIR_DE00397 glyS; Glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D MHIR_DE00465 serS; Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MHIR_DE00132 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MHIR_DE00051 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MHIR_DE00194 alaS; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MHIR_DE00047 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MHIR_DE00046 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:den00194]
D MHIR_DE00537 atpC; ATP synthase epsilon chain K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D MHIR_DE00531 atpH; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:den03000]
D MHIR_DE00206 gltC; HTH-type transcriptional regulator GltC K23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator
D MHIR_DE00678 fabR; HTH-type transcriptional repressor FabR K22105 fabR; TetR/AcrR family transcriptional regulator, fatty acid biosynthesis regulator
D MHIR_DE00222 slyA; Transcriptional regulator SlyA K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D MHIR_DE00440 zur; Zinc uptake regulation protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
D MHIR_DE00608 fnr; Fumarate and nitrate reduction regulatory protein K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
D MHIR_DE00244 birA; Bifunctional ligase/repressor BirA K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D MHIR_DE00547 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D MHIR_DE00648 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
C 03021 Transcription machinery [BR:den03021]
D MHIR_DE00562 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D MHIR_DE00378 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D MHIR_DE00377 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D MHIR_DE00189 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D MHIR_DE00626 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D MHIR_DE00502 rpoH; RNA polymerase sigma factor RpoH K03089 rpoH; RNA polymerase sigma-32 factor
D MHIR_DE00674 nusA; Transcription termination/antitermination protein NusA K02600 nusA; transcription termination/antitermination protein NusA
D MHIR_DE00138 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D MHIR_DE00383 nusG; Transcription termination/antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG
D MHIR_DE00648 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D MHIR_DE00179 greA; Transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D MHIR_DE00274 rho; Transcription termination factor Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:den03019]
D MHIR_DE00210 rne; Ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D MHIR_DE00004 rnc; Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D MHIR_DE00235 rnr; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D MHIR_DE00522 orn; Oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D MHIR_DE00666 deaD; ATP-dependent RNA helicase DeaD K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D MHIR_DE00154 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MHIR_DE00667 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D MHIR_DE00274 rho; Transcription termination factor Rho K03628 rho; transcription termination factor Rho
D MHIR_DE00287 pfkA; 6-phosphofructokinase isozyme 1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
D MHIR_DE00373 dnaK; Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D MHIR_DE00412 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D MHIR_DE00238 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D MHIR_DE00647 pcnB; Poly(A) polymerase I precursor K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
D MHIR_DE00452 rppH; RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
C 03041 Spliceosome
C 03011 Ribosome [BR:den03011]
D MHIR_DE00683 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D MHIR_DE00691 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D MHIR_DE00582 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D MHIR_DE00563 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D MHIR_DE00571 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D MHIR_DE00249 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D MHIR_DE00642 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D MHIR_DE00574 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D MHIR_DE00037 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D MHIR_DE00589 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D MHIR_DE00564 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D MHIR_DE00643 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D MHIR_DE00565 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D MHIR_DE00575 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D MHIR_DE00669 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D MHIR_DE00026 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D MHIR_DE00579 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D MHIR_DE00251 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D MHIR_DE00584 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D MHIR_DE00136 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D MHIR_DE00624 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D MHIR_DE00381 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D MHIR_DE00585 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D MHIR_DE00588 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D MHIR_DE00587 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D MHIR_DE00576 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D MHIR_DE00573 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D MHIR_DE00252 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D MHIR_DE00380 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D MHIR_DE00382 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D MHIR_DE00379 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D MHIR_DE00036 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D MHIR_DE00578 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D MHIR_DE00569 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D MHIR_DE00581 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D MHIR_DE00561 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D MHIR_DE00572 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D MHIR_DE00029 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D MHIR_DE00048 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D MHIR_DE00246 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D MHIR_DE00583 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D MHIR_DE00586 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D MHIR_DE00577 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D MHIR_DE00598 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D MHIR_DE00089 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D MHIR_DE00580 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D MHIR_DE00570 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D MHIR_DE00161 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D MHIR_DE00215 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D MHIR_DE00088 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D MHIR_DE00270 rpmH; 50S ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D MHIR_DE00049 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D MHIR_DE00567 rpmJ; 50S ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D MHIR_DE00605 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D MHIR_DE00442 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D MHIR_DE00408 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D MHIR_DE00443 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:den03009]
D MHIR_DE00004 rnc; Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D MHIR_DE00522 orn; Oligoribonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-]
D MHIR_DE00005 era; GTPase Era K03595 era; GTPase
D MHIR_DE00450 obgE; GTPase ObgE/CgtA K03979 obgE; GTPase [EC:3.6.5.-]
D MHIR_DE00648 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D MHIR_DE00674 nusA; Transcription termination/antitermination protein NusA K02600 nusA; transcription termination/antitermination protein NusA
D MHIR_DE00138 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D MHIR_DE00383 nusG; Transcription termination/antitermination protein NusG K02601 nusG; transcription termination/antitermination protein NusG
D MHIR_DE00163 rsmA; Ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D MHIR_DE00345 rsmC; Ribosomal RNA small subunit methyltransferase C K00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]
D MHIR_DE00507 rsmD; Ribosomal RNA small subunit methyltransferase D K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D MHIR_DE00111 rsmH; Ribosomal RNA small subunit methyltransferase H K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D MHIR_DE00525 rsmI; Ribosomal RNA small subunit methyltransferase I K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D MHIR_DE00234 rlmB; 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D MHIR_DE00181 rlmE; Ribosomal RNA large subunit methyltransferase E K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D MHIR_DE00296 rlmN; Dual-specificity RNA methyltransferase RlmN K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D MHIR_DE00011 rluB; Ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D MHIR_DE00212 rluC; Ribosomal large subunit pseudouridine synthase C K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D MHIR_DE00471 rluD; Ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D MHIR_DE00027 rimM; Ribosome maturation factor RimM K02860 rimM; 16S rRNA processing protein RimM
D MHIR_DE00210 rne; Ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D MHIR_DE00615 yqgF; Putative Holliday junction resolvase K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D MHIR_DE00666 deaD; ATP-dependent RNA helicase DeaD K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D MHIR_DE00541 der; GTPase Der K03977 engA; GTPase
D MHIR_DE00190 spoT; Bifunctional (p)ppGpp synthase/hydrolase SpoT K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D MHIR_DE00672 rbfA; Ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D MHIR_DE00437 ybeY; Endoribonuclease YbeY K07042 ybeY; probable rRNA maturation factor
D MHIR_DE00304 ychF; Ribosome-binding ATPase YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:den03016]
D MHIR_DE00142 cca; Multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D MHIR_DE00284 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MHIR_DE00132 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D MHIR_DE00134 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D MHIR_DE00063 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MHIR_DE00052 metG_1; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D MHIR_DE00481 glnS; Glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D MHIR_DE00371 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MHIR_DE00195 lysS; Lysine--tRNA ligase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D MHIR_DE00501 aspS; Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D MHIR_DE00194 alaS; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D MHIR_DE00630 asnS; Asparagine--tRNA ligase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D MHIR_DE00051 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D MHIR_DE00465 serS; Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D MHIR_DE00618 cysS; Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D MHIR_DE00393 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D MHIR_DE00299 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D MHIR_DE00047 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D MHIR_DE00046 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D MHIR_DE00146 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MHIR_DE00635 trpS; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D MHIR_DE00256 HIT-like protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D MHIR_DE00656 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D MHIR_DE00352 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D MHIR_DE00671 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D MHIR_DE00174 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D MHIR_DE00239 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D MHIR_DE00266 mnmE; tRNA modification GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D MHIR_DE00548 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D MHIR_DE00269 rnpA; Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D MHIR_DE00526 RNaseP_bact_a K01978 rnpB; M1 RNA
D MHIR_DE00346 rnt; Ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D MHIR_DE00376 glyQ_1; Glycine--tRNA ligase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D MHIR_DE00397 glyS; Glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D MHIR_DE00484 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D MHIR_DE00028 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D MHIR_DE00095 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D MHIR_DE00509 tusA; Sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D MHIR_DE00644 tusB; Protein TusB K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D MHIR_DE00645 dsrF; Intracellular sulfur oxidation protein DsrF K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D MHIR_DE00370 tusD; Sulfurtransferase TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D MHIR_DE00319 tusE; Sulfurtransferase TusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D MHIR_DE00375 ygfZ; tRNA-modifying protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
D MHIR_DE00157 tgt; Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D MHIR_DE00070 thiI; tRNA sulfurtransferase K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D MHIR_DE00286 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D MHIR_DE00010 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D MHIR_DE00435 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D MHIR_DE00243 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D MHIR_DE00235 rnr; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D MHIR_DE00667 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:den03012]
D MHIR_DE00673 infB; Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D MHIR_DE00050 infC; Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D MHIR_DE00692 tsf; Elongation factor Ts K02357 tsf; elongation factor Ts
D MHIR_DE00386 tufA; Elongation factor Tu K02358 tuf; elongation factor Tu
D MHIR_DE00641 fusA; Elongation factor G K02355 fusA; elongation factor G
D MHIR_DE00607 prfA; Peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D MHIR_DE00693 frr; Ribosome-recycling factor K02838 frr; ribosome recycling factor
D MHIR_DE00606 prmC; Release factor glutamine methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D MHIR_DE00303 pth; Peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D MHIR_DE00259 infA; Translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D MHIR_DE00413 efp; Elongation factor P K02356 efp; elongation factor P
D MHIR_DE00196 prfB; Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:den03110]
D MHIR_DE00272 clpB; Chaperone protein ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D MHIR_DE00106 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D MHIR_DE00373 dnaK; Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D MHIR_DE00412 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D MHIR_DE00372 dnaJ; Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D MHIR_DE00664 grpE; Protein GrpE K03687 GRPE; molecular chaperone GrpE
D MHIR_DE00552 ibpA; Small heat shock protein IbpA K04080 ibpA; molecular chaperone IbpA
D MHIR_DE00411 groS; 10 kDa chaperonin K04078 groES; chaperonin GroES
D MHIR_DE00182 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D MHIR_DE00415 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D MHIR_DE00165 surA; Chaperone SurA precursor K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]
D MHIR_DE00275 trxA; Thioredoxin-1 K03671 TXN; thioredoxin
D MHIR_DE00434 grxD; Glutaredoxin-4 K07390 grxD; monothiol glutaredoxin
D MHIR_DE00309 dsbB; Disulfide bond formation protein B K03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]
C 04131 Membrane trafficking [BR:den04131]
D MHIR_DE00407 gapA_1; Glyceraldehyde-3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D MHIR_DE00560 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D MHIR_DE00337 pykA; Pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:den03032]
D MHIR_DE00043 rnhA; Ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D MHIR_DE00108 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D MHIR_DE00612 dnaA; Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D MHIR_DE00347 dnaB; Replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D MHIR_DE00625 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D MHIR_DE00348 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MHIR_DE00703 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D MHIR_DE00611 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D MHIR_DE00061 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D MHIR_DE00454 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D MHIR_DE00042 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D MHIR_DE00227 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D MHIR_DE00659 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D MHIR_DE00417 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D MHIR_DE00610 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D MHIR_DE00145 parC; DNA topoisomerase 4 subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D MHIR_DE00539 parE; DNA topoisomerase 4 subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D MHIR_DE00512 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:den03036]
D MHIR_DE00004 rnc; Ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D MHIR_DE00436 hns; DNA-binding protein H-NS K03746 hns; DNA-binding protein H-NS
D MHIR_DE00108 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D MHIR_DE00612 dnaA; Chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D MHIR_DE00545 hspQ; Heat shock protein HspQ K11940 hspQ; heat shock protein HspQ
D MHIR_DE00547 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D MHIR_DE00238 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D MHIR_DE00122 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA
D MHIR_DE00123 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D MHIR_DE00685 zapD; Cell division protein ZapD K18778 zapD; cell division protein ZapD
D MHIR_DE00242 amiB; N-acetylmuramoyl-L-alanine amidase AmiB precursor K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D MHIR_DE00680 minC; Septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D MHIR_DE00681 minD; Septum site-determining protein MinD K03609 minD; septum site-determining protein MinD
D MHIR_DE00682 minE; Cell division topological specificity factor K03608 minE; cell division topological specificity factor
D MHIR_DE00090 mreB; Rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D MHIR_DE00091 mreC; Cell shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D MHIR_DE00092 mreD; Rod shape-determining protein MreD K03571 mreD; rod shape-determining protein MreD
D MHIR_DE00058 mrdB; Rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA
D MHIR_DE00145 parC; DNA topoisomerase 4 subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D MHIR_DE00539 parE; DNA topoisomerase 4 subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D MHIR_DE00548 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D MHIR_DE00332 engB; putative GTP-binding protein EngB K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:den03400]
D MHIR_DE00147 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D MHIR_DE00655 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D MHIR_DE00677 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D MHIR_DE00627 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MHIR_DE00197 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D MHIR_DE00659 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D MHIR_DE00439 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D MHIR_DE00378 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D MHIR_DE00377 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D MHIR_DE00562 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D MHIR_DE00189 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D MHIR_DE00521 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D MHIR_DE00072 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D MHIR_DE00073 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D MHIR_DE00069 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D MHIR_DE00703 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D MHIR_DE00611 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D MHIR_DE00061 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D MHIR_DE00454 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D MHIR_DE00042 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D MHIR_DE00227 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D MHIR_DE00348 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MHIR_DE00464 recB; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
D MHIR_DE00463 recC; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
D MHIR_DE00707 recD2_2; ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
D MHIR_DE00475 recA; Protein RecA K03553 recA; recombination protein RecA
D MHIR_DE00363 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D MHIR_DE00364 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D MHIR_DE00362 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D MHIR_DE00162 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D MHIR_DE00250 priB; Primosomal replication protein n K02686 priB; primosomal replication protein N
D MHIR_DE00417 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D MHIR_DE00610 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D MHIR_DE00512 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D MHIR_DE00108 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D MHIR_DE00547 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D MHIR_DE00436 hns; DNA-binding protein H-NS K03746 hns; DNA-binding protein H-NS
D MHIR_DE00448 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MHIR_DE00418 nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MHIR_DE00419 nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:den03029]
D MHIR_DE00673 infB; Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D MHIR_DE00050 infC; Translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D MHIR_DE00692 tsf; Elongation factor Ts K02357 tsf; elongation factor Ts
D MHIR_DE00386 tufA; Elongation factor Tu K02358 tuf; elongation factor Tu
D MHIR_DE00641 fusA; Elongation factor G K02355 fusA; elongation factor G
D MHIR_DE00005 era; GTPase Era K03595 era; GTPase
D MHIR_DE00146 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D MHIR_DE00063 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D MHIR_DE00501 aspS; Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D MHIR_DE00371 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D MHIR_DE00348 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MHIR_DE00697 bamA; Outer membrane protein assembly factor BamA precursor K07277 SAM50; outer membrane protein insertion porin family
D MHIR_DE00373 dnaK; Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D MHIR_DE00664 grpE; Protein GrpE K03687 GRPE; molecular chaperone GrpE
D MHIR_DE00412 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D MHIR_DE00411 groS; 10 kDa chaperonin K04078 groES; chaperonin GroES
D MHIR_DE00372 dnaJ; Chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D MHIR_DE00174 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D MHIR_DE00434 grxD; Glutaredoxin-4 K07390 grxD; monothiol glutaredoxin
D MHIR_DE00268 yidC; Membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:den02000]
D MHIR_DE00313 msbA; Lipid A export ATP-binding/permease protein MsbA K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D MHIR_DE00260 yheH; putative multidrug resistance ABC transporter ATP-binding/permease protein YheH K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D MHIR_DE00261 cydD; ATP-binding/permease protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
D MHIR_DE00021 mlaD; putative phospholipid ABC transporter-binding protein MlaD K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D MHIR_DE00020 mlaE; putative phospholipid ABC transporter permease protein MlaE K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D MHIR_DE00019 mlaF; putative phospholipid import ATP-binding protein MlaF K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D MHIR_DE00022 mlaC; putative phospholipid-binding protein MlaC precursor K07323 mlaC; phospholipid transport system substrate-binding protein
D MHIR_DE00023 mlaB; putative phospholipid ABC transporter-binding protein MlaB K07122 mlaB; phospholipid transport system transporter-binding protein
D MHIR_DE00554 putative periplasmic iron-binding protein precursor K02077 ABC.ZM.S; zinc/manganese transport system substrate-binding protein
D MHIR_DE00555 mntB; Manganese transport system membrane protein MntB K02075 ABC.ZM.P; zinc/manganese transport system permease protein
D MHIR_DE00556 fhuC; Iron(3+)-hydroxamate import ATP-binding protein FhuC K02074 ABC.ZM.A; zinc/manganese transport system ATP-binding protein
D MHIR_DE00395 lptF; Lipopolysaccharide export system permease protein LptF K07091 lptF; lipopolysaccharide export system permease protein
D MHIR_DE00396 lptG; Lipopolysaccharide export system permease protein LptG K11720 lptG; lipopolysaccharide export system permease protein
D MHIR_DE00014 lptB; Lipopolysaccharide export system ATP-binding protein LptB K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D MHIR_DE00518 lolE; Lipoprotein-releasing system transmembrane protein LolE K09808 lolC_E; lipoprotein-releasing system permease protein
D MHIR_DE00520 lolC; Lipoprotein-releasing system transmembrane protein LolC K09808 lolC_E; lipoprotein-releasing system permease protein
D MHIR_DE00519 lolD; Lipoprotein-releasing system ATP-binding protein LolD K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D MHIR_DE00424 sufC; putative ATP-dependent transporter SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D MHIR_DE00675 mdtK; Multidrug resistance protein MdtK K26939 norM; MATE family, multidrug efflux pump
D MHIR_DE00156 galP; Galactose-proton symporter K08137 galP; MFS transporter, SP family, galactose:H+ symporter
D MHIR_DE00722 ptsN; Nitrogen regulatory protein K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
D MHIR_DE00712 mscS; Small-conductance mechanosensitive channel K03442 mscS; small conductance mechanosensitive channel
D MHIR_DE00031 ompC; Outer membrane protein C precursor K09475 ompC; outer membrane pore protein C
D MHIR_DE00697 bamA; Outer membrane protein assembly factor BamA precursor K07277 SAM50; outer membrane protein insertion porin family
D MHIR_DE00300 bamB; Outer membrane protein assembly factor BamB precursor K17713 bamB; outer membrane protein assembly factor BamB
D MHIR_DE00470 bamD; Outer membrane protein assembly factor BamD precursor K05807 bamD; outer membrane protein assembly factor BamD
D MHIR_DE00660 bamE; Outer membrane protein assembly factor BamE precursor K06186 bamE; outer membrane protein assembly factor BamE
D MHIR_DE00590 tamA; Translocation and assembly module TamA precursor K07278 tamA; translocation and assembly module TamA
D MHIR_DE00591 tamB; Translocation and assembly module TamB K09800 tamB; translocation and assembly module TamB
D MHIR_DE00015 lptA; Lipopolysaccharide export system protein LptA precursor K09774 lptA; lipopolysaccharide export system protein LptA
D MHIR_DE00016 lptC; Lipopolysaccharide export system protein LptC K11719 lptC; lipopolysaccharide export system protein LptC
D MHIR_DE00166 lptD; LPS-assembly protein LptD precursor K04744 lptD; LPS-assembly protein
D MHIR_DE00062 lptE; LPS-assembly lipoprotein LptE precursor K03643 lptE; LPS-assembly lipoprotein
D MHIR_DE00403 pitA; Low-affinity inorganic phosphate transporter 1 K16322 pit; low-affinity inorganic phosphate transporter
D MHIR_DE00276 cvrA; K(+)/H(+) antiporter NhaP2 K11105 cvrA; potassium/hydrogen antiporter
D MHIR_DE00445 mntH; Divalent metal cation transporter MntH K03322 mntH; manganese transport protein
D MHIR_DE00204 murJ; putative peptidoglycan biosynthesis protein MurJ K03980 murJ; putative peptidoglycan lipid II flippase
C 02044 Secretion system [BR:den02044]
D MHIR_DE00613 YGGT family protein K02221 yggT; YggT family protein
D MHIR_DE00127 secA; Protein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D MHIR_DE00415 secB; Protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D MHIR_DE00159 secD; Protein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D MHIR_DE00384 secE; Protein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D MHIR_DE00160 secF; Protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D MHIR_DE00469 secG; Protein-export membrane protein SecG K03075 secG; preprotein translocase subunit SecG
D MHIR_DE00568 secY; Protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D MHIR_DE00025 ffh; Signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D MHIR_DE00506 ftsY; Signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D MHIR_DE00158 yajC; preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D MHIR_DE00268 yidC; Membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
C 02042 Bacterial toxins
C 02022 Two-component system [BR:den02022]
D MHIR_DE00099 phoQ; Virulence sensor histidine kinase PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
D MHIR_DE00098 phoP_1; Virulence transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
D MHIR_DE00336 phoP_2; Alkaline phosphatase synthesis transcriptional regulatory protein PhoP K07662 cpxR; two-component system, OmpR family, response regulator CpxR
C 02035 Bacterial motility proteins
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:den04812]
D MHIR_DE00090 mreB; Rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D MHIR_DE00123 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D MHIR_DE00122 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA
D MHIR_DE00680 minC; Septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D MHIR_DE00681 minD; Septum site-determining protein MinD K03609 minD; septum site-determining protein MinD
D MHIR_DE00682 minE; Cell division topological specificity factor K03608 minE; cell division topological specificity factor
C 04147 Exosome [BR:den04147]
D MHIR_DE00154 eno; Enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D MHIR_DE00407 gapA_1; Glyceraldehyde-3-phosphate dehydrogenase A K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D MHIR_DE00544 pgk; Phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D MHIR_DE00337 pykA; Pyruvate kinase II K00873 PK; pyruvate kinase [EC:2.7.1.40]
D MHIR_DE00271 tsaA; putative peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D MHIR_DE00412 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D MHIR_DE00373 dnaK; Chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D MHIR_DE00549 pgi; Glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D MHIR_DE00386 tufA; Elongation factor Tu K02358 tuf; elongation factor Tu
D MHIR_DE00256 HIT-like protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D MHIR_DE00596 adk; Adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D MHIR_DE00224 lpdA; Dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D MHIR_DE00012 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D MHIR_DE00310 tpiA; Triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D MHIR_DE00560 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:den02048]
D MHIR_DE00123 ftsZ; Cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D MHIR_DE00090 mreB; Rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D MHIR_DE00145 parC; DNA topoisomerase 4 subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D MHIR_DE00539 parE; DNA topoisomerase 4 subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D MHIR_DE00284 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D MHIR_DE00174 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:den01504]
D MHIR_DE00099 phoQ; Virulence sensor histidine kinase PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
D MHIR_DE00098 phoP_1; Virulence transcriptional regulatory protein PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:den03100]
D MHIR_DE00285 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MHIR_DE00294 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D MHIR_DE00356 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00191 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00306 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00616 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D MHIR_DE00055 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D MHIR_DE00441 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D MHIR_DE00429 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D MHIR_DE00399 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D MHIR_DE00444 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D MHIR_DE00388 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MHIR_DE00456 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D MHIR_DE00307 tRNA-His K14226 tRNA-His; tRNA His
D MHIR_DE00409 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D MHIR_DE00280 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00343 tRNA-Ser K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00400 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00430 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00468 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D MHIR_DE00282 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D MHIR_DE00711 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D MHIR_DE00487 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00281 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00398 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00467 tRNA-Met K14230 tRNA-Met; tRNA Met
D MHIR_DE00653 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D MHIR_DE00221 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MHIR_DE00255 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MHIR_DE00308 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D MHIR_DE00030 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00192 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00369 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00609 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D MHIR_DE00387 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MHIR_DE00390 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MHIR_DE00594 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D MHIR_DE00410 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D MHIR_DE00389 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D MHIR_DE00283 tRNA-Val K14237 tRNA-Val; tRNA Val
D MHIR_DE00149 tRNA-Val K14237 tRNA-Val; tRNA Val
D MHIR_DE00408 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D MHIR_DE00443 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D MHIR_DE00442 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D MHIR_DE00254 Bacteria_small_SRP K01983 ffs; SRP RNA
D MHIR_DE00526 RNaseP_bact_a K01978 rnpB; M1 RNA
D MHIR_DE00110 ssrA; transfer-messenger RNA, SsrA K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D MHIR_DE00367 fpr; Ferredoxin--NADP reductase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D MHIR_DE00438 lnt; Apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D MHIR_DE00432 lgt; Prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D MHIR_DE00453 ycfH; putative deoxyribonuclease YcfH K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D MHIR_DE00178 def; Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D MHIR_DE00198 fldA; Flavodoxin-1 K03839 fldA; flavodoxin I
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D MHIR_DE00350 yciS; Inner membrane protein YciS K08992 lapA; lipopolysaccharide assembly protein A
D MHIR_DE00349 tetratricopeptide repeat protein K19804 lapB; lipopolysaccharide assembly protein B
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D MHIR_DE00474 cspC; Cold shock-like protein CspC K03704 cspA; cold shock protein
C 99974 Translation
C 99975 Protein processing
D MHIR_DE00109 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D MHIR_DE00057 nfuA; Fe/S biogenesis protein NfuA K07400 nfuA; Fe/S biogenesis protein NfuA
C 99976 Replication and repair
C 99979 Viral proteins
C 99998 Others
D MHIR_DE00228 ybaB; Nucleoid-associated protein YbaB K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
C 99978 Cell growth
D MHIR_DE00559 yciB; Intracellular septation protein K06190 ispZ; intracellular septation protein
D MHIR_DE00402 envC; Murein hydrolase activator EnvC precursor K22719 envC; murein hydrolase activator
C 99993 Cell motility
D MHIR_DE00257 lpoB; Penicillin-binding protein activator LpoB precursor K07337 K07337; penicillin-binding protein activator
C 99995 Signaling proteins
D MHIR_DE00131 proQ; ProP effector K03607 proQ; ProP effector
D MHIR_DE00094 typA; GTP-binding protein TypA/BipA K06207 typA; GTP-binding protein
C 99992 Structural proteins
D MHIR_DE00466 lolA; Outer-membrane lipoprotein carrier protein precursor K03634 lolA; outer membrane lipoprotein carrier protein
D MHIR_DE00301 lolB; Outer-membrane lipoprotein LolB precursor K02494 lolB; outer membrane lipoprotein LolB
D MHIR_DE00639 mlaA; putative phospholipid-binding lipoprotein MlaA precursor K04754 mlaA; phospholipid-binding lipoprotein MlaA
D MHIR_DE00223 slyB; Outer membrane lipoprotein SlyB precursor K06077 slyB; outer membrane lipoprotein SlyB
D MHIR_DE00698 skp; Chaperone protein Skp precursor K06142 hlpA; outer membrane protein
D MHIR_DE00141 nlpD; Murein hydrolase activator NlpD precursor K06194 nlpD; lipoprotein NlpD
D MHIR_DE00298 rodZ; Cytoskeleton protein RodZ K15539 rodZ; cytoskeleton protein RodZ
C 99994 Others
B
B 09194 Poorly characterized
C 99996 General function prediction only
D MHIR_DE00128 erpA; Iron-sulfur cluster insertion protein ErpA K15724 erpA; iron-sulfur cluster insertion protein
D MHIR_DE00422 iscA; Iron-binding protein IscA K05997 sufA; Fe-S cluster assembly protein SufA
D MHIR_DE00423 sufB; FeS cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D MHIR_DE00425 sufD; FeS cluster assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD
D MHIR_DE00044 ydjM; Inner membrane protein YdjM K07038 K07038; inner membrane protein
D MHIR_DE00427 sufE; Cysteine desulfuration protein SufE K02426 sufE; cysteine desulfuration protein SufE
D MHIR_DE00096 hflD; High frequency lysogenization protein HflD K07153 hflD; high frequency lysogenization protein
C 99997 Function unknown
D MHIR_DE00514 hypothetical protein K09158 K09158; uncharacterized protein
D MHIR_DE00482 hypothetical protein K09791 K09791; uncharacterized protein
D MHIR_DE00686 yacG; DNA gyrase inhibitor YacG K09862 K09862; uncharacterized protein
D MHIR_DE00205 hypothetical protein K09897 K09897; uncharacterized protein
D MHIR_DE00479 hypothetical protein K09898 K09898; uncharacterized protein
!
#
#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: September 18, 2024