+F Repair protein KO
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DNA Repair and Recombination Proteins - Dehalogenimonas sp. WBC-2
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DGWBC_0046 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E DGWBC_0951 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D DGWBC_1493 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DGWBC_0046 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E DGWBC_1354 uracil-DNA glycosylase family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E DGWBC_0440 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E DGWBC_0242 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E DGWBC_0951 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E DGWBC_1469 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E DGWBC_0754 endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E DGWBC_1014 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E DGWBC_1021 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E DGWBC_0240 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E DGWBC_0925 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E DGWBC_0546 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E DGWBC_1140 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E DGWBC_1167 uvrD_pcrA; ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DGWBC_1182 ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DGWBC_0240 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E DGWBC_1021 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F DGWBC_1444 DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F DGWBC_1443 DNA-directed RNA polymerase beta subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F DGWBC_0508 DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F DGWBC_0841 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E DGWBC_1147 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E DGWBC_0772 recombination inhibitory protein MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E DGWBC_0570 mutL; MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
E DGWBC_0030 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E DGWBC_1166 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E DGWBC_0211 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E DGWBC_0824 DNA polymerase III subunits gamma and tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E DGWBC_0926 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E DGWBC_1021 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E DGWBC_1167 uvrD_pcrA; ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DGWBC_1182 ATP-dependent DNA helicase UvrD/PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E DGWBC_0967 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E DGWBC_1779 rexA; RecA K03553 recA; recombination protein RecA
E DGWBC_1372 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E DGWBC_1429 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E DGWBC_0392 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E DGWBC_1652 priA; helicase PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E DGWBC_0921 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E DGWBC_1080 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E DGWBC_1779 rexA; RecA K03553 recA; recombination protein RecA
E DGWBC_1578 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E DGWBC_1211 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E DGWBC_1014 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E DGWBC_0931 DNA recombination mediator protein K03584 recO; DNA repair protein RecO (recombination protein O)
E DGWBC_0928 recombination protein RecR K06187 recR; recombination protein RecR
E DGWBC_0721 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E DGWBC_1372 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E DGWBC_1429 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E DGWBC_0392 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E DGWBC_0921 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E DGWBC_1080 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E DGWBC_0735 hypothetical protein K10979 ku; DNA end-binding protein Ku
E DGWBC_0115 ligD; ATP-dependent DNA ligase LigD K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E DGWBC_0734 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F DGWBC_0194 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F DGWBC_0223 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F DGWBC_0821 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F DGWBC_1014 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F DGWBC_0931 DNA recombination mediator protein K03584 recO; DNA repair protein RecO (recombination protein O)
F DGWBC_0928 recombination protein RecR K06187 recR; recombination protein RecR
F DGWBC_1021 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F DGWBC_0310 ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F DGWBC_0925 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F DGWBC_0546 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D DGWBC_0005 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D DGWBC_1779 rexA; RecA K03553 recA; recombination protein RecA
D DGWBC_0195 lexA; SOS-response repressor and protease LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D DGWBC_0721 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D DGWBC_0967 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D DGWBC_1778 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D DGWBC_1493 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D DGWBC_0296 ribonucleotide reductase of class II K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D DGWBC_0410 ribonucleotide reductase of class II K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D DGWBC_1571 ribonucleotide reductase of class II K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D DGWBC_1642 ribonucleotide reductase of class II K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D DGWBC_1745 ribonucleotide reductase class II K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 9, 2025