+C Kinase KO
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Protein Kinases - Drosophila hydei
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ASerine/threonine kinases: AGC group
B PKA family
C 111601975 cAMP-dependent protein kinase catalytic subunit 2 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 111602262 cAMP-dependent protein kinase catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 111602021 cAMP-dependent protein kinase catalytic subunit 2 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 115483017 cAMP-dependent protein kinase catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
C 111593541 cAMP-dependent protein kinase catalytic subunit 3 isoform X2 K19584 PRKX; protein kinase X [EC:2.7.11.11]
B PKG family
C 111599114 cGMP-dependent protein kinase, isozyme 1 K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
C 111601364 cGMP-dependent protein kinase, isozyme 2 forms cD5/T2 isoform X2 K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
C 111603971 cGMP-dependent protein kinase 1 K07376 PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]
B PKC family [OT]
C 111592580 protein kinase C, brain isozyme isoform X1 K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C 111592669 protein kinase C, eye isozyme K19662 PRKCB; classical protein kinase C beta type [EC:2.7.11.13]
C 111598818 putative protein kinase C delta type homolog isoform X1 K06068 PRKCD; novel protein kinase C delta type [EC:2.7.11.13]
C 111596253 protein kinase C isoform X1 K18050 PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]
C 111602545 atypical protein kinase C isoform X1 K06069 PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]
B PKN family
C 111604183 serine/threonine-protein kinase N isoform X2 K23691 PKN2; serine/threonine-protein kinase N2 [EC:2.7.11.13]
B AUR family [OT]
C 111592049 aurora kinase C K11481 AURKA; aurora kinase A [EC:2.7.11.1]
C 111601532 aurora kinase B-like K11479 AURKB; aurora kinase B [EC:2.7.11.1]
C 111600888 aurora kinase B-like K11479 AURKB; aurora kinase B [EC:2.7.11.1]
B PDK1 family
C 111597413 3-phosphoinositide-dependent protein kinase 1 isoform X1 K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
B AKT/PKB family
C 111604635 RAC serine/threonine-protein kinase K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
B SGK family [OT]
B RSK family [OT]
C 111597436 ribosomal protein S6 kinase 2 beta K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
C 111604760 chromosomal serine/threonine-protein kinase JIL-1 K04445 RPS6KA5; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]
C 111594833 ribosomal protein S6 kinase beta-2 K04688 RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]
C 111595639 ribosomal protein S6 kinase delta-1 K20839 RSKL; ribosomal protein S6 kinase-like
B NDR family
C 111604459 serine/threonine-protein kinase tricorner K08790 STK38; serine/threonine kinase 38 [EC:2.7.11.1]
C 111601991 serine/threonine-protein kinase Warts K08791 LATS1_2; serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1]
B MAST family [OT]
C 111594378 microtubule-associated serine/threonine-protein kinase 3 K08789 MAST; MAST-subfamily protein kinase [EC:2.7.11.37]
C 111604251 serine/threonine-protein kinase greatwall isoform X1 K16309 MASTL; serine/threonine-protein kinase greatwall [EC:2.7.11.36]
B YANK family
C 111605593 serine/threonine-protein kinase 32A isoform X1 K08793 STK32; serine/threonine kinase 32 [EC:2.7.11.1]
B DMPK family [OT]
C 111593451 rho-associated protein kinase 2 K04514 ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.1]
C 111600087 serine/threonine-protein kinase Genghis Khan K16307 CDC42BP; serine/threonine-protein kinase MRCK [EC:2.7.11.1]
C 111595139 citron Rho-interacting kinase K16308 CIT; citron Rho-interacting kinase [EC:2.7.11.35]
B GRK family [OT]
C 111600089 G protein-coupled receptor kinase 1 K00910 ADRBK; beta-adrenergic-receptor kinase [EC:2.7.11.15]
C 111597155 G protein-coupled receptor kinase 2 isoform X1 K08291 GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]
B Other
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
C 111598003 calcium/calmodulin-dependent protein kinase type 1 isoform X1 K08794 CAMK1; calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17]
B CAMK2 family
C 111598041 calcium/calmodulin-dependent protein kinase type II alpha chain isoform X1 K04515 CAMK2; calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
B CAMKL family
C 111593529 serine/threonine-protein kinase BRSK1 isoform X1 K08796 BRSK; BR serine/threonine kinase [EC:2.7.11.1]
C 111596373 serine/threonine-protein kinase grp isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
C 111600095 serine/threonine-protein kinase MARK2 isoform X1 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 111593602 serine/threonine-protein kinase MARK2 K08798 MARK; MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
C 111599071 serine/threonine-protein kinase MARK1 K16310 NIM1; serine/threonine-protein kinase NIM1 [EC:2.7.11.1]
C 111605154 5'-AMP-activated protein kinase catalytic subunit alpha-2 K07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]
C 111604052 serine/threonine-protein kinase par-1 K16311 SIK2; serine/threonine-protein kinase SIK2 [EC:2.7.11.1]
C 111603991 uncharacterized protein LOC111603991 isoform X1 K19009 SIK3; serine/threonine-protein kinase SIK3 [EC:2.7.11.1]
C 111595636 SNF-related serine/threonine-protein kinase K08802 SNRK; SNF related kinase [EC:2.7.11.1]
C 111605588 serine/threonine-protein kinase STK11 K07298 STK11; serine/threonine-protein kinase 11 [EC:2.7.11.1]
B DAPK family
B DCAMKL family
C 111592075 serine/threonine-protein kinase GA29083 isoform X1 K08805 DCLK1_2; doublecortin-like kinase 1/2 [EC:2.7.11.1]
B MAPKAPK family [OT]
C 111592701 MAP kinase-activated protein kinase 2 K04443 MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]
C 111592050 probable serine/threonine-protein kinase MARK-A isoform X1 K04372 MKNK; MAP kinase interacting serine/threonine kinase [EC:2.7.11.1]
B MLCK family
C 111592113 myosin light chain kinase, smooth muscle K00907 MYLK; myosin-light-chain kinase [EC:2.7.11.18]
C 111596139 LOW QUALITY PROTEIN: titin-like K12567 TTN; titin [EC:2.7.11.1]
C 111603056 titin-like isoform X1 K12567 TTN; titin [EC:2.7.11.1]
C 111601697 titin homolog K12567 TTN; titin [EC:2.7.11.1]
B PHK family
C 111605130 phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform X1 K00871 PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]
B PIM family [OT]
B PKD family
C 111605453 serine/threonine-protein kinase D1 isoform X2 K06070 PKD; protein kinase D [EC:2.7.11.13]
C 115483339 serine/threonine-protein kinase D3 isoform X1 K06070 PKD; protein kinase D [EC:2.7.11.13]
B PSK family
B RAD53 family
C 111600369 ovarian-specific serine/threonine-protein kinase Lok K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
B Trio family [OT]
C 111591934 triple functional domain protein isoform X2 K15048 KALRN; kalirin [EC:2.7.11.1]
B TSSK family
C 111602260 testis-specific serine/threonine-protein kinase 3 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 111596693 testis-specific serine/threonine-protein kinase 1-like K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
C 111596703 testis-specific serine/threonine-protein kinase 1 K08811 TSSK; testis-specific serine kinase [EC:2.7.11.1]
B CDPK family
B CASK family
C 111596355 peripheral plasma membrane protein CASK isoform X1 K06103 CASK; calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1]
B Trbl family
C 111592277 tribbles K08814 TRIB1_2; tribbles homolog 1/2
B Other
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
C 111594203 casein kinase I K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 111605118 casein kinase I K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 111605127 casein kinase I-like K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 115482748 casein kinase I K08957 CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]
C 111603019 casein kinase I isoform X1 K08958 CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]
C 111597837 discs overgrown protein kinase K08960 CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]
C 111598840 casein kinase I K14758 HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]
B TTBK family
C 111597799 tau-tubulin kinase homolog Asator isoform X1 K08815 TTBK; tau tubulin kinase [EC:2.7.11.26]
B VRK family
C 111600624 nucleosomal histone kinase 1 K08816 VRK; vaccinia related kinase [EC:2.7.11.1]
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ASerine/threonine kinases: CMGC group
B CDK family
C 111598224 cyclin-dependent kinase 20 K08817 CCRK; cell cycle related kinase [EC:2.7.11.22]
C 111600920 serine/threonine-protein kinase PITSLRE K08818 CDC2L; cell division cycle 2-like [EC:2.7.11.22]
C 111594397 cyclin-dependent kinase 1 K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C 111592371 cyclin-dependent kinase 1-like K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C 111600669 cyclin-dependent kinase 2 K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C 111593550 cyclin-dependent kinase 4 K02089 CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]
C 111593937 cyclin-dependent kinase 5 homolog isoform X1 K02090 CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]
C 111597262 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
C 111597540 cyclin-dependent kinase 8 K02208 CDK8_11; cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23]
C 111593920 cyclin-dependent kinase 9 K02211 CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]
C 111600686 cyclin-dependent kinase 10 K02449 CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]
C 111605729 cyclin-dependent kinase 12 K08819 CDK12_13; cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23]
C 111601607 cyclin-dependent kinase 14 isoform X1 K08821 CDK14; cyclin-dependent kinase 14 [EC:2.7.11.22]
B MAPK family [OT]
C 111594679 mitogen-activated protein kinase ERK-A K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
C 111603998 stress-activated protein kinase JNK K04440 JNK; mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
C 111596502 mitogen-activated protein kinase p38a-like K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 111594644 mitogen-activated protein kinase p38b K04441 P38; p38 MAP kinase [EC:2.7.11.24]
C 111603058 serine/threonine-protein kinase NLK2 K04468 NLK; nemo like kinase [EC:2.7.11.24]
C 115483760 LOW QUALITY PROTEIN: serine/threonine-protein kinase NLK-like K04468 NLK; nemo like kinase [EC:2.7.11.24]
B GSK family [OT]
C 111594254 protein kinase shaggy isoform X4 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
C 111597912 glycogen synthase kinase-3 K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
B CLK family
C 111603562 LOW QUALITY PROTEIN: uncharacterized protein LOC111603562 K08823 CLK2_3; dual specificity protein kinase CLK2/3 [EC:2.7.12.1]
B CDKL family
C 111602279 cyclin-dependent kinase-like 1 isoform X1 K08824 CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]
B DYRK family [OT]
C 111596720 serine/threonine-protein kinase minibrain isoform X1 K08825 DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]
C 111595874 putative dual specificity tyrosine-phosphorylation-regulated kinase 3 homolog isoform X1 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 111600346 dual specificity tyrosine-phosphorylation-regulated kinase 2 K18669 DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1]
C 111601040 homeodomain-interacting protein kinase 2 K08826 HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]
C 111600508 serine/threonine-protein kinase PRP4 homolog K08827 PRPF4B; serine/threonine-protein kinase PRP4 [EC:2.7.11.1]
B RCK family [OT]
C 111598476 serine/threonine-protein kinase dyf-5 K08829 MAK; male germ cell-associated kinase [EC:2.7.11.22]
B SRPK family [OT]
C 111597727 SRSF protein kinase 3 K15409 SRPK1; serine/threonine-protein kinase SRPK1 [EC:2.7.11.1]
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ASerine/threonine kinases: STE group
B STE7 family
C 111598354 dual specificity mitogen-activated protein kinase kinase dSOR1 isoform X1 K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
C 111593410 dual specificity mitogen-activated protein kinase kinase 6 K04432 MAP2K3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
C 111604816 dual specificity mitogen-activated protein kinase kinase 4 K04430 MAP2K4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
C 111593442 dual specificity mitogen-activated protein kinase kinase hemipterous K04431 MAP2K7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
B STE20 family
C 111597940 mitogen-activated protein kinase kinase kinase kinase 5 isoform X1 K08833 MAP4K5; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]
C 111602881 serine/threonine-protein kinase mig-15 isoform X1 K08840 TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]
C 111600950 neither inactivation nor afterpotential protein C K08834 MYO3; myosin III [EC:2.7.11.1]
C 111596534 serine/threonine-protein kinase OSR1 K08835 OXSR1; serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1]
C 111599588 serine/threonine-protein kinase PAK 1 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C 111604884 serine/threonine-protein kinase PAK 2 K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C 111599734 serine/threonine-protein kinase 10 isoform X1 K08836 SLK; STE20-like kinase [EC:2.7.11.1]
C 111603065 putative serine/threonine-protein kinase STE20-like K08271 STRADA; STE20-related kinase adapter protein alpha
C 111597924 serine/threonine-protein kinase hippo K04412 STK3; serine/threonine kinase 3
C 111596184 serine/threonine-protein kinase svkA K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
C 111596790 serine/threonine-protein kinase Tao isoform X1 K04429 TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]
B STE11 family
C 111602613 mitogen-activated protein kinase kinase kinase 4 isoform X1 K04428 MAP3K4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]
C 111596705 mitogen-activated protein kinase kinase kinase 15 K04426 MAP3K5; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
B Other
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ASerine/threonine kinases: TKL group
B IRAK family
C 111597872 serine/threonine-protein kinase pelle K04730 IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]
C 111602009 protein Tube K04733 IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
B LISK family [OT]
C 111605056 LIM domain kinase 1 isoform X1 K05743 LIMK1; LIM domain kinase 1 [EC:2.7.11.1]
B LRRK family
B MLK family
C 111595678 mitogen-activated protein kinase kinase kinase 7-like K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 111601887 mitogen-activated protein kinase kinase kinase 7-like K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 111593773 mitogen-activated protein kinase kinase kinase 7-like K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 111601711 putative mitogen-activated protein kinase kinase kinase 7-like K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 111593077 mitogen-activated protein kinase kinase kinase 7 K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 115482858 tyrosine-protein kinase JAK2-like K04427 MAP3K7; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]
C 111595007 mitogen-activated protein kinase kinase kinase-like isoform X2 K04417 MAP3K9; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]
C 111605082 mitogen-activated protein kinase kinase kinase 13 isoform X1 K04422 MAP3K13; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]
C 111594364 integrin-linked protein kinase homolog pat-4 K06272 ILK; integrin-linked kinase [EC:2.7.11.1]
B RAF family [OT]
C 111602415 raf homolog serine/threonine-protein kinase Raf isoform X1 K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
C 111603563 kinase suppressor of Ras 2 K18529 KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
C 111594150 atrial natriuretic peptide receptor 1 K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 111602938 atrial natriuretic peptide receptor 1 K12323 ANPRA; atrial natriuretic peptide receptor A [EC:4.6.1.2]
C 111599556 retinal guanylyl cyclase 2 K12322 GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]
B BUB family
C 111600886 uncharacterized protein LOC111600886 K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
C 111603937 ras guanine nucleotide exchange factor P K02178 BUB1; checkpoint serine/threonine-protein kinase [EC:2.7.11.1]
B Bud32 family
C 111601658 EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
B CAMKK family
C 111598544 calcium/calmodulin-dependent protein kinase kinase 1 K07359 CAMKK2; calcium/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]
B CDC7 family
C 111600594 cell division cycle 7-related protein kinase K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
C 111597324 cell division cycle 7-related protein kinase isoform X2 K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
B CK2 family
C 111598570 casein kinase II subunit alpha isoform X1 K03097 CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]
B Haspin family
C 111594702 putative serine/threonine-protein kinase haspin homolog K16315 GSG2; serine/threonine-protein kinase haspin [EC:2.7.11.1]
B IKK family [OT]
C 111604649 inhibitor of nuclear factor kappa-B kinase subunit beta K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
C 111594743 serine/threonine-protein kinase TBK1 isoform X1 K05410 TBK1; TANK-binding kinase 1 [EC:2.7.11.10]
B IRE family
C 111596698 serine/threonine-protein kinase/endoribonuclease IRE1 K08852 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
B MOS family
B NAK family [OT]
C 111595760 uncharacterized protein LOC111595760 isoform X1 K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
C 111595672 cyclin-G-associated kinase K08855 GAK; cyclin G-associated kinase [EC:2.7.11.1]
C 111603390 serine/threonine-protein kinase 16 K08856 STK16; serine/threonine kinase 16 [EC:2.7.11.1]
B NEK family
C 111598826 serine/threonine-protein kinase Nek2 K20872 NEK2; serine/threonine-protein kinase Nek2 [EC:2.7.11.1]
C 111594825 serine/threonine-protein kinase Nek8 K20877 NEK8; serine/threonine-protein kinase Nek8 [EC:2.7.11.1]
B NKF1 family
C 111596628 sperm motility kinase X isoform X1 K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
C 111596348 serine/threonine-protein kinase meng-po K08858 SBK; serine/threonine-protein kinase SBK [EC:2.7.11.1]
B NKF2 family
C 111597360 probable serine/threonine-protein kinase DDB_G0267686 K05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
C 111603032 nuclear receptor-binding protein homolog K08875 NRBP; nuclear receptor-binding protein
B PEK family [OT]
C 111598506 eukaryotic translation initiation factor 2-alpha kinase isoform X1 K08860 EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]
C 111597889 eIF-2-alpha kinase GCN2 K16196 EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]
B PLK family [OT]
C 111592326 serine/threonine-protein kinase polo K06631 PLK1; polo-like kinase 1 [EC:2.7.11.21]
C 111605730 serine/threonine-protein kinase PLK4 K08863 PLK4; polo-like kinase 4 [EC:2.7.11.21]
B SCY1 family [OT]
C 111597830 N-terminal kinase-like protein K08876 SCYL1; SCY1-like protein 1
C 111598737 SCY1-like protein 2 isoform X2 K17541 SCYL2; SCY1-like protein 2
C 111602807 SCY1-like protein 2 K17541 SCYL2; SCY1-like protein 2
C 111592098 protein-associating with the carboxyl-terminal domain of ezrin K17542 SCYL3; SCY1-like protein 3
B Slob family
C 111595622 PX domain-containing protein kinase-like protein K17543 PXK; PX domain-containing protein kinase-like protein
B TBCK family
C 111605134 TBC domain-containing protein kinase-like protein K17544 TBCK; TBC domain-containing protein kinase-like protein
B TLK family
C 111603345 histone-lysine N-methyltransferase 2D isoform X1 K08864 TLK; tousled-like kinase [EC:2.7.11.1]
B TOPK family
C 111593428 lymphokine-activated killer T-cell-originated protein kinase K08865 PBK; PDZ-binding kinase [EC:2.7.12.2]
B TTK family
C 111599604 dual specificity protein kinase Ttk K08866 TTK; serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1]
B ULK family [OT]
C 111596164 serine/threonine-protein kinase fused K06228 FU; fused [EC:2.7.11.1]
C 111597293 serine/threonine-protein kinase unc-51 isoform X1 K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
C 111595715 serine/threonine-protein kinase ULK3 isoform X1 K21358 ULK3; serine/threonine-protein kinase ULK3 [EC:2.7.11.1]
B VPS15 family
C 111599429 phosphoinositide 3-kinase regulatory subunit 4 K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
B WEE family
C 111605645 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase K06633 PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]
C 111605015 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
B Wnk family
C 111591876 uncharacterized protein LOC111591876 isoform X1 K08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]
B ABC1 family
C 111604476 uncharacterized aarF domain-containing protein kinase 5 isoform X1 K08869 ADCK; aarF domain-containing kinase
C 111593895 uncharacterized aarF domain-containing protein kinase 1 K08869 ADCK; aarF domain-containing kinase
C 111593466 atypical kinase COQ8B, mitochondrial K08869 ADCK; aarF domain-containing kinase
B Alpha family [OT]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
C 111604602 pyruvate dehydrogenase (acetyl-transferring) kinase, mitochondrial K00898 PDK2_3_4; pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
B PIKK family [OT]
C 111593396 serine/threonine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
C 111599446 serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
C 111592907 serine/threonine-protein kinase Tor K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
C 111598845 serine/threonine-protein kinase Smg1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
C 111599996 transcription-associated protein 1 K08874 TRRAP; transformation/transcription domain-associated protein
B RIO family [OT]
C 111592769 serine/threonine-protein kinase RIO1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
C 111599653 serine/threonine-protein kinase RIO2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 111605471 serine/threonine-protein kinase RIO3 isoform X1 K08872 RIOK3; RIO kinase 3 [EC:2.7.11.1]
B TAF1 family
C 111600833 transcription initiation factor TFIID subunit 1 K03125 TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]
B TIF1 family [OT]
C 111600732 transcription intermediary factor 1-alpha isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
B Other
C 111593455 protein mahjong isoform X1 K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
B Bacterial family
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
C 111593819 activin receptor type-1 isoform X1 K04675 ACVR1; activin receptor type-1 [EC:2.7.11.30]
C 111599898 bone morphogenetic protein receptor type-1B K13578 BMPR1B; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
C 111597654 TGF-beta receptor type-1 isoform X1 K04674 TGFBR1; TGF-beta receptor type-1 [EC:2.7.11.30]
B TGFBR2 family [OT]
C 111596865 activin receptor type-2A K13596 ACVR2B; activin receptor type-2B [EC:2.7.11.30]
C 111597498 bone morphogenetic protein receptor type-2 K04671 BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]
C 111594132 uncharacterized protein LOC111594132 isoform X1 K04669 TGFBRX; TGF-beta receptor, other
C 111596329 inhibin beta A chain K04669 TGFBRX; TGF-beta receptor, other
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
C 111592533 epidermal growth factor receptor isoform X1 K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
B INSR family [OT]
C 111600855 insulin-like receptor K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
C 115483782 insulin-like peptide receptor K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
C 111599590 insulin-like peptide receptor K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
B PDGFR family [OT]
B FGFR family [OT]
C 111601307 tyrosine kinase receptor Cad96Ca K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
C 111600927 fibroblast growth factor receptor homolog 2 K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
B VEGFR family [OT]
C 111596228 vascular endothelial growth factor receptor 1 isoform X1 K05096 FLT1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]
B MET family
B TRK family [OT]
B EPH family [OT]
C 111597835 ephrin type-B receptor 1-B isoform X1 K05110 EPHB1; Eph receptor B1 [EC:2.7.10.1]
B AXL family
B ALK family
C 111593842 ALK tyrosine kinase receptor K05119 ALK; anaplastic lymphoma kinase [EC:2.7.10.1]
B TIE family
B ROR family
C 111594391 tyrosine-protein kinase transmembrane receptor Ror K05122 ROR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]
B DDR family
C 111602370 discoidin domain-containing receptor 2 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
C 111602263 uncharacterized protein LOC111602263 K05125 DDR2; discoidin domain receptor family member 2 [EC:2.7.10.1]
B RET family
C 111599187 uncharacterized protein LOC111599187 K05126 RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]
B ROS family
B CCK family
C 111595405 tyrosine-protein kinase-like otk K05127 PTK7; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]
B RYK family
C 111600410 LOW QUALITY PROTEIN: tyrosine-protein kinase Drl K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
C 111600321 tyrosine-protein kinase Dnt K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
C 111598802 tyrosine-protein kinase RYK K05128 RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]
B MUSK family
C 111595330 tyrosine-protein kinase transmembrane receptor Ror2 K05129 MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]
B LMR family [OT]
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ANon-receptor tyrosine kinases
B ABL family
C 111592453 tyrosine-protein kinase Abl isoform X1 K06619 ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]
B ACK family
C 111604767 uncharacterized protein LOC111604767 isoform X1 K08886 TNK2; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]
B CSK family
C 111598516 probable serine/threonine-protein kinase cdc7 K05728 CSK; c-src tyrosine kinase [EC:2.7.10.2]
B FAK family
C 111600150 focal adhesion kinase 1 isoform X1 K05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]
B FES family
C 111595692 tyrosine-protein kinase Fer isoform X1 K08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]
B JAK family [OT]
C 111601813 tyrosine-protein kinase hopscotch K04447 JAK2; Janus kinase 2 [EC:2.7.10.2]
B SRC family
C 111603185 tyrosine-protein kinase Src42A isoform X1 K08892 FRK; fyn-related kinase [EC:2.7.10.2]
C 111599411 tyrosine-protein kinase Src64B isoform X1 K05704 SRC; tyrosine-protein kinase Src [EC:2.7.10.2]
B TEC family
C 111596216 tyrosine-protein kinase Btk29A isoform X1 K07364 TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]
B SYK family
C 111598016 tyrosine-protein kinase Shark K17512 SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]
B Other
B Bacterial
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AHistidine kinases
B OmpR family
B NarL family
B Spo family [OT]
B CitB family [OT]
B LytTR family [OT]
B NtrC family
B CheA family [OT]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024
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Classification taken and modified from Hanks (2003)