+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Dactylosporangium matsuzakiense

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS E Dmats_32710 fabD; ACP S-malonyltransferase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains D Chivosazol hybrid PKS-NRPS E Dmats_32710 fabD; ACP S-malonyltransferase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS E Dmats_32710 fabD; ACP S-malonyltransferase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains D Difficidin PKS E Dmats_32710 fabD; ACP S-malonyltransferase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS E Dmats_23790 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D Dmats_05500 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein D Dmats_26235 MbtH family protein K05375 mbtH; MbtH protein D Dmats_26515 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D Dmats_26180 4'-phosphopantetheinyl transferase superfamily protein K02362 entD; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7] C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C Dmats_27605 epoxide hydrolase K21159 sgcF; epoxide hydrolase B Methylase B Glycosyltransferase B Halogenase C Dmats_22070 NAD(P)/FAD-dependent oxidoreductase K14257 ctcP; tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-] C Dmats_32665 chlorinating enzyme K15650 cmaB; non-haem Fe2+, alpha-ketoglutarate-dependent halogenase B beta-Branched incorporating proteins C Dmats_32630 polyketide beta-ketoacyl:ACP synthase K00646 pksF; malonyl-[acp] decarboxylase [EC:4.1.1.124] C Dmats_32635 phosphopantetheine-binding protein K15337 acpK; polyketide biosynthesis acyl carrier protein C Dmats_32645 acyl carrier protein K15337 acpK; polyketide biosynthesis acyl carrier protein C Dmats_32640 hydroxymethylglutaryl-CoA synthase family protein K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C Dmats_32745 hydroxymethylglutaryl-CoA synthase family protein K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C Dmats_32740 enoyl-CoA hydratase/isomerase family protein K15312 pksH; 3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase [EC:4.2.1.181] B Others C Dmats_05360 flavin reductase family protein K21297 ctcQ; flavin reductase (NADH) [EC:1.5.1.36] C Dmats_33650 flavin reductase family protein K21297 ctcQ; flavin reductase (NADH) [EC:1.5.1.36] C Dmats_05325 SDR family oxidoreductase K15944 snoaF; nogalaviketone/aklaviketone reductase [EC:1.1.1.- 1.1.1.362] # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase C Dmats_13290 PLP-dependent aminotransferase family protein K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103] B Others C Dmats_07870 aminotransferase class V-fold PLP-dependent enzyme K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17] C Dmats_13345 hppD; 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C Dmats_13285 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C Dmats_33750 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C Dmats_26505 aspartate/glutamate racemase family protein K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 19, 2024