+E Ubiquitin system KO
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Ubiquitin System - Drosophila melanogaster (fruit fly)
%
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C Dmel_CG32744 Ubi-p5E; Ubiquitin-5E, isoform B K08770 UBC; ubiquitin C
C Dmel_CG11700 CG11700; uncharacterized protein K08770 UBC; ubiquitin C
C Dmel_CG11624 Ubi-p63E; Ubiquitin-63E, isoform D K08770 UBC; ubiquitin C
C Dmel_CG2960 RpL40; ribosomal protein L40, isoform B K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C Dmel_CG5271 RpS27A; ribosomal protein S27A K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C Dmel_CG10679 Nedd8; Nedd8 ubiquitin like modifier, isoform B K12158 NEDD8; ubiquitin-like protein Nedd8
C Dmel_CG15697 RpS30; ribosomal protein S30, isoform C K02983 RP-S30e; small subunit ribosomal protein S30e
C Dmel_CG4494 Sumo; small ubiquitin like modifier, isoform B K12160 SUMO; small ubiquitin-related modifier
C Dmel_CG12334 Atg8b; Autophagy-related 8b, isoform B K08341 GABARAP; GABA(A) receptor-associated protein
C Dmel_CG32672 Atg8a; Autophagy-related 8a, isoform B K08341 GABARAP; GABA(A) receptor-associated protein
C Dmel_CG10861 Atg12; Autophagy-related 12 K08336 ATG12; ubiquitin-like protein ATG12
C Dmel_CG33276 Urm1; Ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
C Dmel_CG34191 Ufm1; Ubiquitin-fold modifier 1, isoform A K12162 UFM1; ubiquitin-fold modifier 1
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C Dmel_CG1782 Uba1; ubiquitin activating enzyme 1, isoform C K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C Dmel_CG12276 Aos1; activator of SUMO 1 K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C Dmel_CG7528 Uba2; Ubiquitin-like activating enzyme 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C Dmel_CG13343 Uba3; Ubiquitin-like activating enzyme 3 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C Dmel_CG7828 APP-BP1; beta-Amyloid precursor protein binding protein 1, isoform B K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C Dmel_CG13090 Uba4; Ubiquitin-like activating enzyme 4, isoform B K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C Dmel_CG1749 Uba5; Ubiquitin-like activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C Dmel_CG5489 Atg7; Autophagy-related 7, isoform A K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C Dmel_CG2013 Ubc6; ubiquitin conjugating enzyme 6, isoform C K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C Dmel_CG10682 vih; vihar K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C Dmel_CG7425 eff; effete, isoform B K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C Dmel_CG10862 CG10862; uncharacterized protein K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C Dmel_CG2574 CG2574; uncharacterized protein K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C Dmel_CG5440 CG5440; uncharacterized protein, isoform C K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C Dmel_CG6720 Ubc2; ubiquitin conjugating enzyme 2, isoform C K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C Dmel_CG40045 CG40045; uncharacterized protein, isoform A K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C Dmel_CG9602 Ubc87F; ubiquitin conjugating enzyme 87F K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C Dmel_CG4443 Ubc7; ubiquitin conjugating enzyme 7, isoform B K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C Dmel_CG2257 UbcE2H; ubiquitin conjugating enzyme E2H, isoform B K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C Dmel_CG14739 CG14739; uncharacterized protein K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C Dmel_CG5823 CG5823; uncharacterized protein, isoform B K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C Dmel_CG8284 Ubc4; ubiquitin conjugating enzyme 4, isoform B K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C Dmel_CG12799 Ubc84D; ubiquitin conjugating enzyme 84D K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C Dmel_CG5788 Ubc10; ubiquitin conjugating enzyme 10 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C Dmel_CG17030 CG17030; uncharacterized protein K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C Dmel_CG18319 ben; bendless, isoform B K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Dmel_CG3473 CG3473; uncharacterized protein, isoform B K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Dmel_CG10254 CG10254; uncharacterized protein, isoform C K10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]
C Dmel_CG2924 CG2924; uncharacterized protein, isoform E K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C Dmel_CG4502 CG4502; uncharacterized protein, isoform A K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C Dmel_CG7656 CG7656; uncharacterized protein, isoform F K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C Dmel_CG8188 CG8188; uncharacterized protein, isoform B K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C Dmel_CG7220 CG7220; uncharacterized protein, isoform E K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C Dmel_CG6303 Bruce; BIR repeat containing ubiquitin-conjugating enzyme, isoform B K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C Dmel_CG3018 lwr; lesswright, isoform C K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C Dmel_CG7375 UbcE2M; NEDD8-conjugating enzyme UbcE2M, isoform B K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C Dmel_CG6877 Atg3; Autophagy-related 3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C Dmel_CG12821 Atg10; Autophagy-related 10, isoform B K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C Dmel_CG8386 Ufc1; Ubiquitin-fold modifier conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C Dmel_CG6190 Ube3a; ubiquitin protein ligase E3A K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C Dmel_CG5087 CG5087; uncharacterized protein, isoform B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C Dmel_CG3356 CG3356; uncharacterized protein K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C Dmel_CG7326 CG7326; uncharacterized protein, isoform B K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C Dmel_CG4943 Smurf; SMAD specific E3 ubiquitin protein ligase, isoform B K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C Dmel_CG4244 Su(dx); suppressor of deltex, isoform F K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C Dmel_CG42574 ctrip; circadian trip, isoform B K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C Dmel_CG42279 Nedd4; Nedd4, isoform J K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Dmel_CG8184 HUWE1; HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1, isoform H K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C Dmel_CG4238 CG4238; uncharacterized protein, isoform E K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C Dmel_CG9484 hyd; hyperplastic discs, isoform A K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C Dmel_CG9576 Phf7; PHD finger protein 7, isoform B K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C Dmel_CG5354 pie; pineapple eye, isoform B K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C Dmel_CG11734 HERC2; HECT and RLD domain containing protein 2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C Dmel_CG9153 Herc4; HECT and RLD domain containing E3 ubiquitin ligase 4, isoform C K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C Dmel_CG42797 Hecw; hecw ubiquitin protein ligase, isoform E K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C Dmel_CG5604 Ufd4; ubiquitin fusion-degradation 4-like K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C HECT type E3 associated proteins
D Dmel_CG32177 Ndfip; Nedd4 family interacting protein K25839 NDFIP; NEDD4 family-interacting protein
B U-box type E3
C Dmel_CG11070 Ube4A; ubiquitination factor E4A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C Dmel_CG9934 Ube4B; ubiquitination factor E4B, isoform B K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C Dmel_CG5203 STUB1; STIP1 homology and U-box containing protein 1 K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C Dmel_CG7747 CG7747; uncharacterized protein K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C Dmel_CG5519 Prp19; Pre-RNA processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C Dmel_CG3231 snama; something that sticks like glue, isoform B K10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]
C Dmel_CG2218 CG2218; uncharacterized protein, isoform B K10600 UBOX5; U-box domain-containing protein 5
B Single Ring-finger type E3
C BRE1 proteins
D Dmel_CG10542 Bre1; Bre1, isoform B K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D Dmel_CG7037 Cbl; Cbl proto-oncogene, isoform B K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D Dmel_CG9949 sina; seven in absentia, isoform C K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
D Dmel_CG13030 sinah; sina homologue K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
C Ligand of Numb proteins
D Dmel_CG1783 Slip1; SLo interacting protein 1, isoform A K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D Dmel_CG4080 CG4080; uncharacterized protein, isoform B K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D Dmel_CG13442 CG13442; uncharacterized protein K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D Dmel_CG9855 CG9855; uncharacterized protein, isoform C K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D Dmel_CG10761 CG10761; uncharacterized protein K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D Dmel_CG16781 CG16781; uncharacterized protein, isoform B K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D Dmel_CG17991 CG17991; uncharacterized protein K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D Dmel_CG1317 CG1317; uncharacterized protein, isoform C K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D Dmel_CG3647 stc; shuttle craft, isoform B K12236 NFX1; transcriptional repressor NF-X1
D Dmel_CG15011 CG15011; uncharacterized protein K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D Dmel_CG5212 Pli; pellino, isoform B K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D Dmel_CG7864 Pex10; peroxin 10, isoform B K13346 PEX10; peroxin-10
D Dmel_CG3639 Pex12; peroxin 12, isoform B K13345 PEX12; peroxin-12
D Dmel_CG7081 Pex2; peroxin 2 K06664 PEX2; peroxin-2
C RBR proteins
D Dmel_CG10523 park; parkin, isoform B K04556 PARK2; parkin [EC:2.3.2.31]
D Dmel_CG5659 ari-1; ariadne 1, isoform D K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D Dmel_CG5709 ari-2; ariadne 2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D Dmel_CG11321 LUBEL; linear ubiquitin E3 ligase, isoform E K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
D Dmel_CG17019 CG17019; uncharacterized protein, isoform B K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
C TRAF proteins
D Dmel_CG10961 Traf6; TNF-receptor-associated factor 6 K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
C TRIM/RBCC proteins
D Dmel_CG10719 brat; brain tumor, isoform F K11997 TRIM2_3; tripartite motif-containing protein 2/3
D Dmel_CG31721 Trim9; tripartite motif containing 9, isoform B K10649 TRIM9_67; tripartite motif-containing protein 9/67
D Dmel_CG5206 bon; bonus, isoform B K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D Dmel_CG8419 CG8419; uncharacterized protein K12021 TRIM45; tripartite motif-containing protein 45
D Dmel_CG42396 wech; wech, isoform D K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
D Dmel_CG15105 tn; thin, isoform C K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D Dmel_CG9086 Ubr1; Ubr1 ubiquitin ligase, isoform B K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D Dmel_CG42593 Ubr3; Ubr3 ubiquitin ligase, isoform A K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D Dmel_CG14472 poe; purity of essence, isoform B K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D Dmel_CG15141 CG15141; uncharacterized protein K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D Dmel_CG8293 Diap2; Death-associated inhibitor of apoptosis 2, isoform A K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D Dmel_CG12284 Diap1; Death-associated inhibitor of apoptosis 1, isoform D K16061 BIRC7_8; baculoviral IAP repeat-containing protein 7/8
D Dmel_CG5555 CG5555; uncharacterized protein, isoform B K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D Dmel_CG10263 Hakai; hakai, isoform F K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Dmel_CG31716 Cnot4; CCR4-NOT transcription complex subunit 4, isoform H K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D Dmel_CG11281 snky; sneaky K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D Dmel_CG3929 dx; deltex K06058 DTX; deltex [EC:2.3.2.27]
D Dmel_CG12812 Fancl; fancl, isoform A K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D Dmel_CG11984 Kcmf1; potassium channel modulatory factor 1, isoform E K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D Dmel_CG32210 Ltn1; listerin E3 ubiquitin protein ligase 1 K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D Dmel_CG11360 CG11360; uncharacterized protein, isoform C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D Dmel_CG5841 mib1; mind bomb 1, isoform A K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D Dmel_CG17492 mib2; mind bomb 2, isoform B K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D Dmel_CG5347 CG5347; uncharacterized protein K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D Dmel_CG7184 Mkrn1; makorin 1, isoform C K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D Dmel_CG12477 CG12477; uncharacterized protein K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D Dmel_CG5334 CG5334; uncharacterized protein K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D Dmel_CG1134 Mul1; mitochondrial E3 ubiquitin protein ligase 1, isoform B K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D Dmel_CG32592 hiw; highwire, isoform B K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D Dmel_CG12489 dnr1; defense repressor 1, isoform B K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D Dmel_CG11988 neur; neuralized, isoform A K01931 NEUR; protein neuralized [EC:2.3.2.27]
D Dmel_CG16947 Rchy1; ring finger and CHY zinc finger domain containing 1, isoform B K10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]
D Dmel_CG16807 roq; roquin, isoform C K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D Dmel_CG13025 mus302; mutagen-sensitive 302, isoform B K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D Dmel_CG5595 Sce; Sex combs extra K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D Dmel_CG10981 dgrn; degringolade, isoform D K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D Dmel_CG32581 sordd2; suppression of retinal degeneration disease 1 upon overexpression 2, isoform B K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D Dmel_CG8974 sordd1; suppression of retinal degeneration disease 1 upon overexpression 1, isoform C K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D Dmel_CG12099 CG12099; uncharacterized protein, isoform B K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D Dmel_CG32850 Rnf11; ring finger protein 11, isoform B K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D Dmel_CG10277 gzl; godzilla E3 ubiquitin protein ligase, isoform D K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D Dmel_CG13344 CG13344; uncharacterized protein, isoform C K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D Dmel_CG2617 CG2617; uncharacterized protein, isoform B K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D Dmel_CG9381 mura; murashka, isoform A K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D Dmel_CG9014 CG9014; uncharacterized protein, isoform B K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D Dmel_CG17033 elgi; early girl, isoform B K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D Dmel_CG6923 CG6923; uncharacterized protein, isoform C K10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]
D Dmel_CG11982 Iru; iruka K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D Dmel_CG15814 CG15814; uncharacterized protein, isoform A K15698 RNF121_175; RING finger protein 121/175
D Dmel_CG6752 Kpc1; Kip1 ubiquitination-promoting complex subunit 1, isoform B K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D Dmel_CG2304 Trc8; TRC8 ring finger protein, isoform D K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D Dmel_CG8786 Rnf146; ring finger protein 146, isoform C K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D Dmel_CG9941 Mrgn1; mahogunin ring finger 1 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D Dmel_CG7694 CG7694; uncharacterized protein, isoform B K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D Dmel_CG4813 RNF220; ring finger protein 220 K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D Dmel_CG6686 CG6686; uncharacterized protein, isoform B K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D Dmel_CG7376 CG7376; uncharacterized protein, isoform B K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D Dmel_CG4909 POSH; plenty of SH3s K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D Dmel_CG1937 sip3; septin interacting protein 3, isoform B K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D Dmel_CG14646 CG14646; uncharacterized protein, isoform B K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D Dmel_CG15104 Topors; topoisomerase I-interacting protein, isoform B K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
D Dmel_CG5140 nopo; no poles, isoform B K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D Dmel_CG11414 CG11414; uncharacterized protein K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D Dmel_CG14435 CG14435; uncharacterized protein, isoform C K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
B Atypical E3
C Dmel_CG11329 Nse1; Non-SMC element 1, isoform B K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C Dmel_CG11138 Pits; protein interacting with Ttk69 and Sin3A, isoform D K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C Dmel_CG15104 Topors; topoisomerase I-interacting protein, isoform B K10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]
C Dmel_CG11856 Nup358; nucleoporin 358kD, isoform B K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C Dmel_CG8068 Su(var)2-10; suppressor of variegation 2-10, isoform J K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C Dmel_CG13732 qjt; quijote, isoform B K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C Dmel_CG31053 nenya; nenya K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C Dmel_CG12200 narya; narya K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C Dmel_CG2709 vilya; vilya K25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]
C Dmel_CG16863 CG16863; uncharacterized protein, isoform B K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C Dmel_CG1104 Ufl1; UFM1 specific ligase 1, isoform C K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C Dmel_CG7427 SCCRO; squamous cell carcinoma-related oncogene, isoform E K17822 DCUN1D1_2; DCN1-like protein 1/2
C Dmel_CG13322 SCCRO3; squamous cell carcinoma-related oncogene 3, isoform A K17823 DCUN1D3; DCN1-like protein 3
C Dmel_CG6597 SCCRO4; squamous cell carcinoma-related oncogene 4, isoform E K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit Ring-finger type E3
C SCF complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E Dmel_CG1877 Cul1; cullin 1, isoform D K03347 CUL1; cullin 1
E Dmel_CG11261 Cul6; cullin 6 K03347 CUL1; cullin 1
D Adaptor protein
E Dmel_CG16983 SkpA; SKP1-related A, isoform H K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG12227 SkpF; SKP1-related F K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG8881 SkpB; SKP1-related B K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG11942 SkpE; SKP1-related E K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG11941 SkpC; SKP1-related C K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG12700 SkpD; SKP1-related D K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG15800 CG15800; uncharacterized protein K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG43089 CG43089; uncharacterized protein, isoform B K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E Dmel_CG3412 slmb; supernumerary limbs, isoform C K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E Dmel_CG33969 CG33969; uncharacterized protein, isoform A K10262 FBXW4; F-box and WD-40 domain protein 4
E Dmel_CG9144 Fbw5; F-box and WD repeat domain containing 5 K10263 FBXW5; F-box and WD-40 domain protein 5
E Dmel_CG15010 ago; archipelago, isoform C K10260 FBXW7; F-box and WD-40 domain protein 7
E Dmel_CG9772 Skp2; S-phase kinase-associated protein 2, isoform A K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E Dmel_CG9003 CG9003; uncharacterized protein, isoform B K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E Dmel_CG1839 Fbxl4; F box and leucine-rich-repeat gene 4 K10270 FBXL4; F-box and leucine-rich repeat protein 4
E Dmel_CG13213 Fbl6; F-box and leucine-rich repeat protein 6, isoform A K10272 FBXL6; F-box and leucine-rich repeat protein 6
E Dmel_CG4221 Fbxl7; F-box and leucine-rich repeat protein 7 K10273 FBXL7; F-box and leucine-rich repeat protein 7
E Dmel_CG8272 CG8272; uncharacterized protein, isoform B K10275 FBXL9; F-box and leucine-rich repeat protein 9
E Dmel_CG12402 CG12402; uncharacterized protein, isoform B K10275 FBXL9; F-box and leucine-rich repeat protein 9
E Dmel_CG11033 Kdm2; lysine demethylase 2, isoform C K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E Dmel_CG9952 Ppa; partner of paired, isoform B K10280 FBXL14; F-box and leucine-rich repeat protein 14
E Dmel_CG8873 jet; jetlag, isoform B K10281 FBXL15; F-box and leucine-rich repeat protein 15
E Dmel_CG32085 CG32085; uncharacterized protein K10282 FBXL16; F-box and leucine-rich repeat protein 16
E Dmel_CG5961 CG5961; uncharacterized protein, isoform B K10295 FBXO9; F-box protein 9
E Dmel_CG9461 FBXO11; F-box protein 11, isoform B K10297 FBXO11; F-box protein 11
E Dmel_CG11658 CG11658; uncharacterized protein, isoform A K10305 FBXO25_32; F-box protein 25/32
E Dmel_CG3428 pall; pallbearer K10306 FBXO28; F-box protein 28
E Dmel_CG11866 dmpd; dampened, isoform B K10306 FBXO28; F-box protein 28
E Dmel_CG4911 CG4911; uncharacterized protein, isoform B K10310 FBXO33; F-box protein 33
E Dmel_CG11044 CG11044; uncharacterized protein K10314 FBXO39; F-box protein 39
E Dmel_CG6758 Fbxo42; F-box protein 42 K10317 FBXO42; F-box protein 42
E Dmel_CG4643 Fsn; F-box synaptic protein, isoform A K10319 FBXO45; F-box protein 45
C Cul2 complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E Dmel_CG1512 Cul2; cullin 2, isoform B K03870 CUL2; cullin 2
D Adoptor protein
E Dmel_CG9291 EloC; elongin C, isoform B K03872 ELOC; elongin-C
E Dmel_CG4204 EloB; elongin B K03873 ELOB; elongin-B
D Target recognizing subunit
E Dmel_CG13221 Vhl; von Hippel-Lindau, isoform B K03871 VHL; von Hippel-Lindau disease tumor supressor
E Dmel_CG6098 Lrr47; Leucine-rich repeat 47, isoform B K10348 LRR1; LRR-repeat protein 1
E Dmel_CG6966 CG6966; uncharacterized protein, isoform B K25805 FEM1A_C; protein fem-1 homolog A/C
E Dmel_CG11896 m-cup; mann-cup, isoform B K25805 FEM1A_C; protein fem-1 homolog A/C
E Dmel_CG9025 Fem-1; Fem-1, isoform B K10349 FEM1B; protein fem-1 homolog B
E Dmel_CG10695 Pat1; protein interacting with APP tail-1, isoform B K25806 APPBP2; amyloid protein-binding protein 2
E Dmel_CG12081 CG12081; uncharacterized protein, isoform B K25808 KLHDC3; kelch domain-containing protein 3
E Dmel_CG5186 slim; scruin like at the midline, isoform A K25809 KLHDC10; kelch domain-containing protein 10
E Dmel_CG12084 CG12084; uncharacterized protein, isoform A K10350 ZYG11; Zyg-11 protein
E Dmel_CG34401 Dora; dorado, isoform A K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E Dmel_CG42616 Cul3; cullin 3, isoform C K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E Dmel_CG17754 CG17754; uncharacterized protein, isoform E K10442 KLHL1_4_5; kelch-like protein 1/4/5
E Dmel_CG7210 kel; kelch, isoform B K10443 KLHL2_3; kelch-like protein 2/3
E Dmel_CG12423 klhl10; kelch like family member 10, isoform A K10448 KLHL10; kelch-like protein 10
E Dmel_CG15097 CG15097; uncharacterized protein, isoform C K10454 KLHL17; kelch-like protein 17 (actinfilin)
E Dmel_CG3571 KLHL18; kelch like family member 18, isoform C K10455 KLHL18; kelch-like protein 18
E Dmel_CG3962 Keap1; Keap1, isoform A K10456 KLHL19; kelch-like protein 19
E Dmel_CG6224 dbo; diablo, isoform A K10457 KLHL20; kelch-like protein 20
E Dmel_CG9426 CG9426; uncharacterized protein K13956 IPP; actin-binding protein IPP
E Dmel_CG43226 lute; lute, isoform B K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E Dmel_CG16952 CG16952; uncharacterized protein, isoform D K10479 BTBD7; BTB/POZ domain-containing protein 7
E Dmel_CG1826 BTBD9; BTB (POZ) domain containing 9, isoform B K10481 BTBD9; BTB/POZ domain-containing protein 9
E Dmel_CG8411 gcl; germ cell-less, isoform A K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E Dmel_CG43980 CG43980; uncharacterized protein, isoform C K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E Dmel_CG5701 RhoBTB; Rho-related BTB domain containing, isoform B K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E Dmel_CG10465 CG10465; uncharacterized protein K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E Dmel_CG10440 twz; tiwaz, isoform B K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E Dmel_CG32810 inc; insomniac, isoform D K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E Dmel_CG9467 CG9467; uncharacterized protein, isoform B K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E Dmel_CG10830 Ktl; Kctd12-like, isoform B K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E Dmel_CG14647 CG14647; uncharacterized protein K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E Dmel_CG12537 rdx; roadkill, isoform E K10523 SPOP; speckle-type POZ protein
E Dmel_CG3711 Lztr1; leucine zipper like transcription regulator 1, isoform E K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E Dmel_CG8711 Cul4; cullin 4, isoform B K10609 CUL4; cullin 4
D Adoptor protein
E Dmel_CG7769 pic; piccolo K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E Dmel_CG6093 abo; abnormal oocyte K10571 DET1; de-etiolated-1
E Dmel_CG31855 CG31855; uncharacterized protein, isoform B K11792 DDA1; DET1- and DDB1-associated protein 1
E Dmel_CG3925 ohgt; ohgata K11793 CRBN; cereblon
E Dmel_CG10080 mahj; mahjong, isoform B K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E Dmel_CG11295 l(2)dtl; lethal-(2)-denticleless K11790 DTL; denticleless
E Dmel_CG42233 CG42233; uncharacterized protein K11800 DCAF5; DDB1- and CUL4-associated factor 5
E Dmel_CG14614 wap; wings apart, isoform C K11805 DCAF7; DDB1- and CUL4-associated factor 7
E Dmel_CG8001 CG8001; uncharacterized protein, isoform B K11804 DCAF8; DDB1- and CUL4-associated factor 8
E Dmel_CG5124 adp; adipose, isoform B K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E Dmel_CG1523 CG1523; uncharacterized protein K11802 DCAF10; DDB1- and CUL4-associated factor 10
E Dmel_CG9945 CG9945; uncharacterized protein, isoform A K11801 DCAF11; DDB1- and CUL4-associated factor 11
E Dmel_CG3313 DCAF12; DDB1 and CUL4 associated factor 12, isoform B K11803 DCAF12; DDB1- and CUL4-associated factor 12
E Dmel_CG7275 CG7275; uncharacterized protein K11806 DCAF13; DDB1- and CUL4-associated factor 13
E Dmel_CG6325 CG6325; uncharacterized protein K11791 DCAF15; DDB1- and CUL4-associated factor 15
E Dmel_CG31132 BRWD3; BRWD3 K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E Dmel_CG7611 CG7611; uncharacterized protein, isoform I K22382 WDR26; WD repeat-containing protein 26
E Dmel_CG5543 CG5543; uncharacterized protein K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
E Dmel_CG8998 Roc2; regulator of cullins 2, isoform B K10611 RBX2; RING-box protein 2
D Cullin
E Dmel_CG1401 Cul5; cullin 5 K10612 CUL5; cullin 5
D Adoptor protein
E Dmel_CG9291 EloC; elongin C, isoform B K03872 ELOC; elongin-C
E Dmel_CG4204 EloB; elongin B K03873 ELOB; elongin-B
D Target recognizing subunit
E Dmel_CG15154 Socs36E; suppressor of cytokine signaling at 36E, isoform C K04698 SOCS5; suppressor of cytokine signaling 5
E Dmel_CG2160 Socs44A; suppressor of cytokine signaling at 44A K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E Dmel_CG8146 Socs16D; suppressor of cytokine signaling at 16D, isoform B K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E Dmel_CG31006 stops; slow termination of phototransduction, isoform C K10339 ASB17; ankyrin repeat and SOCS box protein 17
E Dmel_CG2944 gus; gustavus, isoform G K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E Dmel_CG10516 CG10516; uncharacterized protein K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E Dmel_CG14041 SP555; SP555, isoform C K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E Dmel_CG1900 Rab40; Rab40, isoform C K07928 RAB40; Ras-related protein Rab-40
C Cul7 complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E Dmel_CG16983 SkpA; SKP1-related A, isoform H K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG12227 SkpF; SKP1-related F K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG8881 SkpB; SKP1-related B K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG11942 SkpE; SKP1-related E K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG11941 SkpC; SKP1-related C K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG12700 SkpD; SKP1-related D K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG15800 CG15800; uncharacterized protein K03094 SKP1; S-phase kinase-associated protein 1
E Dmel_CG43089 CG43089; uncharacterized protein, isoform B K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E Dmel_CG16982 Roc1a; regulator of cullins 1a, isoform D K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Dmel_CG16988 Roc1b; regulator of cullins 1b K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E Dmel_CG34440 lmgA; lemming A, isoform A K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E Dmel_CG3060 mr; morula K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E Dmel_CG4274 fzy; fizzy K03363 CDC20; cell division cycle 20, cofactor of APC complex
E Dmel_CG16783 fzr2; fizzy-related 2 K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
E Dmel_CG3000 fzr; fizzy-related, isoform A K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E Dmel_CG9198 shtd; shattered K03348 APC1; anaphase-promoting complex subunit 1
E Dmel_CG8610 Cdc27; cell division cycle 27, isoform B K03350 APC3; anaphase-promoting complex subunit 3
E Dmel_CG32707 APC4; anaphase promoting complex subunit 4, isoform C K03351 APC4; anaphase-promoting complex subunit 4
E Dmel_CG10850 ida; imaginal discs arrested K03352 APC5; anaphase-promoting complex subunit 5
E Dmel_CG6759 Cdc16; cell division cycle 16 K03353 APC6; anaphase-promoting complex subunit 6
E Dmel_CG14444 APC7; anaphase promoting complex subunit 7, isoform A K03354 APC7; anaphase-promoting complex subunit 7
E Dmel_CG2508 Cdc23; cell division cycle 23, isoform B K03355 APC8; anaphase-promoting complex subunit 8
E Dmel_CG31687 CG31687; uncharacterized protein, isoform B K03355 APC8; anaphase-promoting complex subunit 8
E Dmel_CG11419 APC10; anaphase promoting complex subunit 10 K03357 APC10; anaphase-promoting complex subunit 10
E Dmel_CG33981 CG33981; uncharacterized protein, isoform A K12456 APC13; anaphase-promoting complex subunit 13
E Dmel_CG15237 CG15237; uncharacterized protein K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D Dmel_CG7948 spn-A; spindle A, isoform A K04482 RAD51; DNA repair protein RAD51
C KPC complex
D Dmel_CG6752 Kpc1; Kip1 ubiquitination-promoting complex subunit 1, isoform B K12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]
D Dmel_CG11025 Kpc2; Kip1 ubiquitination-promoting complex subunit 2, isoform C K12174 KPC2; Kip1 ubiquitination-promoting complex protein 2
C LUBAC complex
D Dmel_CG11321 LUBEL; linear ubiquitin E3 ligase, isoform E K11974 RNF31; E3 ubiquitin-protein ligase RNF31 [EC:2.3.2.31]
C CTLH complex
D Dmel_CG3295 Sou; souji K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D Dmel_CG42236 RanBPM; Ran-binding protein M, isoform D K23334 RANBP9_10; Ran-binding protein 9/10
D Dmel_CG8811 muskelin; muskelin, isoform C K23337 MKLN1; muskelin
D Dmel_CG31357 Kaz; katazuke K18624 MAEA; macrophage erythroblast attacher
D Dmel_CG6617 Hou; houki K23338 GID8; glucose-induced degradation protein 8
D Dmel_CG1989 Ype; yippee, isoform A K23339 YPEL5; protein yippee-like 5
D Dmel_CG7611 CG7611; uncharacterized protein, isoform I K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
C LMBR1L-GP78-UBAC2 complex
D Dmel_CG5807 lili; lilipod, isoform A K25215 LMBR1L; protein LMBR1L
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D Dmel_CG5366 Cand1; Cullin-associated and neddylation-dissociated 1, isoform B K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D Dmel_CG7168 CG7168; uncharacterized protein K22558 COMMD2; COMM domain containing 2
D Dmel_CG12106 CG12106; uncharacterized protein K22559 COMMD3; COMM domain containing 3
D Dmel_CG34039 CG34039; uncharacterized protein K22560 COMMD4; COMM domain containing 4
D Dmel_CG33677 LSm-4; uncharacterized protein K22561 COMMD5; COMM domain containing 5
D Dmel_CG46302 CG46302; uncharacterized protein K22564 COMMD8; COMM domain containing 8
D Dmel_CG2371 Vlet; valette, isoform B K22566 COMMD10; COMM domain containing 10
D Dmel_CG9951 CG9951; uncharacterized protein K23343 CCDC22; coiled-coil domain-containing protein 22
D Dmel_CG5862 Ddrgk1; DDRGK domain containing 1 K23344 DDRGK1; DDRGK domain-containing protein 1
D Dmel_CG30496 CG30496; uncharacterized protein K23345 GLMN; glomulin
D Dmel_CG8892 CG8892; uncharacterized protein, isoform E K24350 UBXN7; UBX domain-containing protein 7
D Dmel_CG15120 CG15120; uncharacterized protein K26163 PACRG; parkin coregulated gene protein
D Dmel_CG8715 lig; lingerer, isoform D K26545 UBAP2; ubiquitin-associated protein 2
D Dmel_CG10933 Dlish; dachs ligand with SH3s K26546 Dlish; SH3 domain-containing protein Dlish
#
ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D Dmel_CG8445 caly; calypso, isoform A K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D Dmel_CG4265 Uch; ubiquitin carboxy-terminal hydrolase, isoform B K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D Dmel_CG3431 Uch-L5; ubiquitin carboxy-terminal hydrolase L5, isoform B K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
D Dmel_CG1950 Uch-L5R; Uch-L5-related K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D Dmel_CG5603 CYLD; cylindromatosis, isoform E K08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]
D Dmel_CG15817 Usp1; ubiquitin specific protease 1, isoform E K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
D Dmel_CG14619 Usp2; ubiquitin specific protease 2, isoform F K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D Dmel_CG12082 Usp5; ubiquitin specific protease 5, isoform B K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D Dmel_CG8334 Usp32; ubiquitin specific protease 32, isoform H K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D Dmel_CG1490 Usp7; Ubiquitin-specific protease 7, isoform B K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D Dmel_CG5798 Usp8; ubiquitin specific protease 8, isoform B K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D Dmel_CG1945 faf; fat facets, isoform A K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D Dmel_CG32479 Usp10; ubiquitin specific protease 10, isoform B K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D Dmel_CG7023 Usp12-46; Ubiquitin-specific protease 12/46 K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D Dmel_CG5384 Usp14; ubiquitin specific protease 14, isoform B K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D Dmel_CG4165 Usp16-45; ubiquitin specific protease 16/45, isoform F K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D Dmel_CG8494 Usp20-33; ubiquitin specific protease 20/33 K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D Dmel_CG4166 not; non-stop, isoform C K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D Dmel_CG3016 Usp30; ubiquitin specific protease 30, isoform B K11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]
D Dmel_CG30421 Usp15-31; ubiquitin specific protease 15/31, isoform B K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D Dmel_CG5794 puf; puffyeye, isoform D K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D Dmel_CG8830 DUBAI; deubiquitinating apoptotic inhibitor, isoform A K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D Dmel_CG5505 scny; scrawny, isoform D K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
D Dmel_CG5486 Usp47; ubiquitin specific protease 47, isoform B K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
C OTU
D Dmel_CG4968 CG4968; uncharacterized protein K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D Dmel_CG6091 Duba; deubiquitinating enzyme A, isoform G K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D Dmel_CG7857 CG7857; uncharacterized protein K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D Dmel_CG9448 trbd; trabid K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D Dmel_CG3781 Josd; josephin domain containing K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D Dmel_CG7332 CG7332; uncharacterized protein, isoform B K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D Dmel_CG4751 CG4751; uncharacterized protein K24173 MPND; MPN domain-containing protein
D Dmel_CG18174 Rpn11; regulatory particle non-ATPase 11 K03030 PSMD14; 26S proteasome regulatory subunit N11
D Dmel_CG2224 CG2224; uncharacterized protein, isoform B K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D Dmel_CG12231 CG12231; uncharacterized protein K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
D Dmel_CG7222 CG7222; uncharacterized protein, isoform B K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
B UBL-specific proteases (ULPs)
C Dmel_CG12359 Ulp1; Ulp1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C Dmel_CG32110 CG32110; uncharacterized protein K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C Dmel_CG12717 pira; pirate, isoform B K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C Dmel_CG10107 velo; veloren, isoform D K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C Dmel_CG8493 Den1; deneddylase 1, isoform C K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C Dmel_CG1503 CG1503; uncharacterized protein, isoform B K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C Dmel_CG4265 Uch; ubiquitin carboxy-terminal hydrolase, isoform B K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C Dmel_CG6972 CG6972; uncharacterized protein, isoform B K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D Dmel_CG3889 CSN1b; COP9 signalosome subunit 1b K12175 GPS1; COP9 signalosome complex subunit 1
D Dmel_CG4697 CSN1a; COP9 signalosome subunit 1a K12175 GPS1; COP9 signalosome complex subunit 1
D Dmel_CG9556 alien; alien, isoform D K12176 COPS2; COP9 signalosome complex subunit 2
D Dmel_CG18332 CSN3; COP9 signalosome subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D Dmel_CG8725 CSN4; COP9 signalosome subunit 4, isoform B K12178 COPS4; COP9 signalosome complex subunit 4
D Dmel_CG14884 CSN5; COP9 signalosome subunit 5, isoform A K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D Dmel_CG6932 CSN6; COP9 signalosome subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D Dmel_CG2038 CSN7; COP9 signalosome subunit 7 K12180 COPS7; COP9 signalosome complex subunit 7
D Dmel_CG42522 CSN8; COP9 signalosome subunit 8 K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024