+F Repair protein KO
#
DNA Repair and Recombination Proteins - Dipodomys merriami (Merriam's kangaroo rat)
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 138819875 Mgmt; (RefSeq) methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 138821665 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 138808437 Alkbh2; (RefSeq) DNA oxidative demethylase ALKBH2 isoform X1 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 138829825 DNA oxidative demethylase ALKBH2-like isoform X1 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 138833962 Alkbh3; (RefSeq) alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1 K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 138819281 Ascc3; (RefSeq) activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
C BER (base exicision repair)
D DNA glycosylases
E 138808520 Ung; (RefSeq) uracil-DNA glycosylase isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 138829806 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 138840675 Ccno; (RefSeq) cyclin-O K10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]
E 138806103 Tdg; (RefSeq) G/T mismatch-specific thymine DNA glycosylase isoform X1 K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 138825331 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 138825368 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 138816420 Smug1; (RefSeq) single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 138803405 adenine DNA glycosylase-like isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 138823622 adenine DNA glycosylase-like isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 138822721 methyl-CpG-binding domain protein 4-like K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E 138824830 methyl-CpG-binding domain protein 4-like K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E 138822681 N-glycosylase/DNA lyase-like isoform X1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 138824787 N-glycosylase/DNA lyase isoform X1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 138841897 Neil1; (RefSeq) endonuclease 8-like 1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 138823424 Neil2; (RefSeq) endonuclease 8-like 2 K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
E 138823045 Neil3; (RefSeq) endonuclease 8-like 3 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
E 138814491 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E 138825315 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 138828475 Apex1; (RefSeq) DNA repair nuclease/redox regulator APEX1 isoform X1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 138839586 Apex2; (RefSeq) DNA-(apurinic or apyrimidinic site) endonuclease 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 138812757 Pold1; (RefSeq) DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 138822043 Pold2; (RefSeq) DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
F 138836404 Pold3; (RefSeq) DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 138821746 DNA polymerase epsilon catalytic subunit A isoform X1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 138821856 DNA polymerase epsilon catalytic subunit A-like isoform X1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 138830818 Pole2; (RefSeq) DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 138820319 Pole3; (RefSeq) DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 138820442 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 138826818 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 138804568 Pole4; (RefSeq) DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 138816751 Pcna; (RefSeq) proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 138818118 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 138833823 Fen1; (RefSeq) flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 138812843 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 138814626 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 138823136 Polb; (RefSeq) DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 138811248 DNA repair protein XRCC1-like isoform X1 K10803 XRCC1; DNA-repair protein XRCC1
E 138813477 DNA repair protein XRCC1-like isoform X1 K10803 XRCC1; DNA-repair protein XRCC1
E 138830656 Lig3; (RefSeq) DNA ligase 3 isoform X1 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 138810523 tyrosyl-DNA phosphodiesterase 1-like isoform X1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 138831496 Tdp1; (RefSeq) tyrosyl-DNA phosphodiesterase 1 isoform X1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 138817843 Aptx; (RefSeq) aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 138815231 Aplf; (RefSeq) aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 138812774 Pnkp; (RefSeq) bifunctional polynucleotide phosphatase/kinase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 138814125 Hmgb1; (RefSeq) high mobility group protein B1 isoform X1 K10802 HMGB1; high mobility group protein B1
E 138835037 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1
E 138835092 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1
E 138808694 Poll; (RefSeq) DNA polymerase lambda isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 138827596 Parp1; (RefSeq) poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 138828439 Parp2; (RefSeq) poly [ADP-ribose] polymerase 2 isoform X1 K28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]
E 138814182 Parp4; (RefSeq) protein mono-ADP-ribosyltransferase PARP4 K10798 PARP3_4; protein mono-ADP-ribosyltransferase 3/4 [EC:2.4.2.-]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 138822734 DNA repair protein complementing XP-C cells-like isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 138824844 DNA repair protein complementing XP-C cells-like isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 138808794 UV excision repair protein RAD23 homolog A isoform X1 K10839 RAD23; UV excision repair protein RAD23
F 138817772 UV excision repair protein RAD23 homolog A-like isoform X1 K10839 RAD23; UV excision repair protein RAD23
F 138819670 Rad23b; (RefSeq) UV excision repair protein RAD23 homolog B K10839 RAD23; UV excision repair protein RAD23
F 138840001 Cetn2; (RefSeq) centrin-2 K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 138811784 Rbx1; (RefSeq) E3 ubiquitin-protein ligase RBX1 isoform X1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 138825683 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 138833739 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 138813963 cullin-4A isoform X1 K10609 CUL4; cullin 4
F 138817641 cullin-4A isoform X1 K10609 CUL4; cullin 4
F 138840089 Cul4b; (RefSeq) cullin-4B isoform X1 K10609 CUL4; cullin 4
F 138833836 Ddb1; (RefSeq) DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 138833922 Ddb2; (RefSeq) DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 138813233 Polr2a; (RefSeq) DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 138821096 Polr2b; (RefSeq) DNA-directed RNA polymerase II subunit RPB2 isoform X1 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 138806931 Polr2c; (RefSeq) DNA-directed RNA polymerase II subunit RPB3 isoform X1 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 138804940 Polr2d; (RefSeq) DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 138817762 Polr2e; (RefSeq) DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 138811737 Polr2f; (RefSeq) DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 138810671 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 138833791 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 138832190 Polr2h; (RefSeq) DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 138834859 Polr2j; (RefSeq) DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F 138811784 Rbx1; (RefSeq) E3 ubiquitin-protein ligase RBX1 isoform X1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 138825683 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 138833739 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 138813963 cullin-4A isoform X1 K10609 CUL4; cullin 4
F 138817641 cullin-4A isoform X1 K10609 CUL4; cullin 4
F 138840089 Cul4b; (RefSeq) cullin-4B isoform X1 K10609 CUL4; cullin 4
F 138833836 Ddb1; (RefSeq) DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 138840810 Ercc8; (RefSeq) DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 138825972 Ercc6; (RefSeq) DNA excision repair protein ERCC-6 K10841 ERCC6; DNA excision repair protein ERCC-6
F 138826498 Uvssa; (RefSeq) UV-stimulated scaffold protein A K23720 UVSSA; UV-stimulated scaffold protein A
F 138813414 Elof1; (RefSeq) transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 138804923 Ercc3; (RefSeq) general transcription and DNA repair factor IIH helicase/translocase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 138812914 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 138813969 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 138834067 Gtf2h1; (RefSeq) general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 138832979 general transcription factor IIH subunit 2 isoform X1 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 138828746 Gtf2h3; (RefSeq) general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 138828263 Gtf2h4; (RefSeq) general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 138819534 Gtf2h5; (RefSeq) general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 138832970 Cdk7; (RefSeq) cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 138832907 Ccnh; (RefSeq) cyclin-H K06634 CCNH; cyclin H
E 138833887 Mnat1; (RefSeq) CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 138830768 Rpa1; (RefSeq) replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 138829002 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 138838229 Rpa2; (RefSeq) replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 138809712 Rpa3; (RefSeq) replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
E 138814331 replication protein A 30 kDa subunit-like K10741 RPA4; replication factor A4
D Other NER factors
E 138819088 Xpa; (RefSeq) DNA repair protein complementing XP-A cells K10847 XPA; DNA-repair protein complementing XP-A cells
E 138812912 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 138814008 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 138814519 Ercc4; (RefSeq) DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 138825617 DNA repair endonuclease XPF-like K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 138813982 Ercc5; (RefSeq) DNA excision repair protein ERCC-5 K10846 ERCC5; DNA excision repair protein ERCC-5
E 138812843 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 138814626 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 138826181 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 138830122 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 138808404 Ccdc117; (RefSeq) coiled-coil domain-containing protein 117 K27967 CCDC117; coiled-coil domain-containing protein 117
E 138821207 Ciao1; (RefSeq) probable cytosolic iron-sulfur protein assembly protein CIAO1 K24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1
E 138806969 cytosolic iron-sulfur assembly component 2B K26403 CIAO2; cytosolic iron-sulfur assembly component 2
E 138808924 Ciao2a; (RefSeq) cytosolic iron-sulfur assembly component 2A isoform X1 K26403 CIAO2; cytosolic iron-sulfur assembly component 2
E 138815332 cytosolic iron-sulfur assembly component 2B K26403 CIAO2; cytosolic iron-sulfur assembly component 2
E 138823002 Cul3; (RefSeq) cullin-3 isoform X1 K03869 CUL3; cullin 3
E 138821349 cullin-5 K10612 CUL5; cullin 5
E 138838813 cullin-5 K10612 CUL5; cullin 5
E 138839070 Eloc; (RefSeq) elongin-C K03872 ELOC; elongin-C
E 138814618 elongin-B K03873 ELOB; elongin-B
E 138825465 elongin-B K03873 ELOB; elongin-B
E 138804249 elongin-A3 member D-like K15076 ELOA; elongin-A
E 138804277 elongin-A3 member D-like K15076 ELOA; elongin-A
E 138804382 elongin-A3 member D-like K15076 ELOA; elongin-A
E 138833366 elongin-A3 member D-like K15076 ELOA; elongin-A
E 138833375 elongin-A3 member D-like K15076 ELOA; elongin-A
E 138838306 Eloa; (RefSeq) elongin-A K15076 ELOA; elongin-A
E 138809106 ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 138817994 Ubap2; (RefSeq) ubiquitin-associated protein 2 isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
E 138821594 Ubap2l; (RefSeq) ubiquitin-associated protein 2-like isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 138829263 Msh2; (RefSeq) DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E 138807208 DNA mismatch repair protein Msh3-like isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3
E 138832921 Msh3; (RefSeq) DNA mismatch repair protein Msh3 isoform X1 K08736 MSH3; DNA mismatch repair protein MSH3
E 138829265 Msh6; (RefSeq) DNA mismatch repair protein Msh6 isoform X1 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 138809197 Pms1; (RefSeq) PMS1 protein homolog 1 isoform X1 K10864 PMS1; DNA mismatch repair protein PMS1
E 138816641 Mlh1; (RefSeq) DNA mismatch repair protein Mlh1 isoform X1 K08734 MLH1; DNA mismatch repair protein MLH1
E 138834795 Pms2; (RefSeq) mismatch repair endonuclease PMS2 isoform X1 K10858 PMS2; DNA mismatch repair protein PMS2
E 138832199 Mlh3; (RefSeq) DNA mismatch repair protein Mlh3 isoform X1 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 138812757 Pold1; (RefSeq) DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 138822043 Pold2; (RefSeq) DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
E 138836404 Pold3; (RefSeq) DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 138830768 Rpa1; (RefSeq) replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 138829002 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 138838229 Rpa2; (RefSeq) replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 138809712 Rpa3; (RefSeq) replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
E 138814331 replication protein A 30 kDa subunit-like K10741 RPA4; replication factor A4
D RFC (replication factor C)
E 138820697 Rfc1; (RefSeq) replication factor C subunit 1 isoform X1 K10754 RFC1; replication factor C subunit 1
E 138832214 Rfc4; (RefSeq) replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
E 138836895 Rfc2; (RefSeq) replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 138807778 replication factor C subunit 5 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
E 138814107 Rfc3; (RefSeq) replication factor C subunit 3 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
E 138837698 replication factor C subunit 5-like isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 138816751 Pcna; (RefSeq) proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 138835602 Exo1; (RefSeq) exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 138814125 Hmgb1; (RefSeq) high mobility group protein B1 isoform X1 K10802 HMGB1; high mobility group protein B1
E 138835037 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1
E 138835092 high mobility group protein B1 K10802 HMGB1; high mobility group protein B1
E 138812843 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 138814626 DNA ligase 1-like isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 138816289 Wdr76; (RefSeq) WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 138804948 Mre11; (RefSeq) double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 138807895 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 138808202 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 138805839 Nbn; (RefSeq) nibrin K10867 NBN; nibrin
D BRCA1-core complex
E 138830896 Brca1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 138824072 Bard1; (RefSeq) BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 138830896 Brca1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 138821064 Abraxas1; (RefSeq) BRCA1-A complex subunit Abraxas 1 isoform X1 K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 138837592 Uimc1; (RefSeq) BRCA1-A complex subunit RAP80 isoform X1 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 138808265 Babam1; (RefSeq) BRISC and BRCA1-A complex member 1 K20776 BABAM; BRISC and BRCA1-A complex member 1
E 138829154 Babam2; (RefSeq) BRISC and BRCA1-A complex member 2 isoform X1 K12173 BRE; BRCA1-A complex subunit BRE
E 138839947 Brcc3; (RefSeq) lys-63-specific deubiquitinase BRCC36 isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
E 138840690 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 138830896 Brca1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 138830353 Brip1; (RefSeq) LOW QUALITY PROTEIN: Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 138815985 Topbp1; (RefSeq) DNA topoisomerase 2-binding protein 1 isoform X1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 138830896 Brca1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 138832085 Rbbp8; (RefSeq) DNA endonuclease RBBP8 isoform X1 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E 138804948 Mre11; (RefSeq) double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 138807895 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 138808202 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 138805839 Nbn; (RefSeq) nibrin K10867 NBN; nibrin
D BRCA complex
E 138830896 Brca1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 138814115 Brca2; (RefSeq) breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 138815057 Palb2; (RefSeq) partner and localizer of BRCA2 isoform X1 K10897 PALB2; partner and localizer of BRCA2
E 138816216 Rad51; (RefSeq) DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 138816216 Rad51; (RefSeq) DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 138833117 Rad51b; (RefSeq) DNA repair protein RAD51 homolog 2 isoform X1 K10869 RAD51L1; RAD51-like protein 1
E 138830597 Rad51c; (RefSeq) DNA repair protein RAD51 homolog 3 isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 138830655 Rad51d; (RefSeq) DNA repair protein RAD51 homolog 4 isoform X1 K10871 RAD51L3; RAD51-like protein 3
E 138810187 Xrcc2; (RefSeq) DNA repair protein XRCC2 K10879 XRCC2; DNA-repair protein XRCC2
E 138810400 Xrcc3; (RefSeq) DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E 138804535 Rad52; (RefSeq) DNA repair protein RAD52 homolog isoform X1 K10873 RAD52; DNA repair and recombination protein RAD52
E 138820398 DNA repair protein RAD52 homolog isoform X1 K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E 138803387 Rad54l; (RefSeq) DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 138807673 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 138815949 helicase ARIP4 isoform X1 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 138805863 Rad54b; (RefSeq) DNA repair and recombination protein RAD54B isoform X1 K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 138820004 Recql; (RefSeq) ATP-dependent DNA helicase Q1 isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 138823187 Wrn; (RefSeq) bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 138842096 Blm; (RefSeq) recQ-like DNA helicase BLM isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 138806106 ATP-dependent DNA helicase Q4-like isoform X1 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 138829638 ATP-dependent DNA helicase Q4-like K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 138807336 Recql5; (RefSeq) ATP-dependent DNA helicase Q5 isoform X1 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 138842096 Blm; (RefSeq) recQ-like DNA helicase BLM isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 138808262 Top3b; (RefSeq) DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 138830806 Top3a; (RefSeq) DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 138836867 Rmi1; (RefSeq) recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 138814440 Rmi2; (RefSeq) recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E 138830768 Rpa1; (RefSeq) replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 138829002 replication protein A 32 kDa subunit-like K10739 RFA2; replication factor A2
E 138838229 Rpa2; (RefSeq) replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 138809712 Rpa3; (RefSeq) replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
E 138814331 replication protein A 30 kDa subunit-like K10741 RPA4; replication factor A4
D Protein phosphatase 4
E 138815003 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 138841725 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 138832151 Ppp4r1; (RefSeq) serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 138824755 Ppp4r2; (RefSeq) serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 138810513 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 138829300 Ppp4r3b; (RefSeq) serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 138831487 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 138839696 Ppp4r3c; (RefSeq) protein PPP4R3C K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 138810485 serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
E 138833106 serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 138818596 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 138824320 AP-5 complex subunit beta-1-like K19022 AP5B1; AP-5 complex subunit beta-1
E 138834098 Ap5m1; (RefSeq) AP-5 complex subunit mu-1 K19023 AP5M1; AP-5 complex subunit mu-1
E 138816779 Ap5s1; (RefSeq) AP-5 complex subunit sigma-1 K19024 AP5S1; AP-5 complex subunit sigma-1
E 138834765 Ap5z1; (RefSeq) AP-5 complex subunit zeta-1 isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 138836988 Smc5; (RefSeq) structural maintenance of chromosomes protein 5 isoform X1 K22803 SMC5; structural maintenance of chromosomes protein 5
E 138829057 Smc6; (RefSeq) structural maintenance of chromosomes protein 6 isoform X1 K22804 SMC6; structural maintenance of chromosomes protein 6
E 138822483 Lratd1; (RefSeq) protein LRATD1 K22805 FAM84A; protein FAM84A
E 138815043 Nsmce1; (RefSeq) non-structural maintenance of chromosomes element 1 homolog isoform X1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 138806000 Nsmce2; (RefSeq) E3 SUMO-protein ligase NSE2 isoform X1 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 138842018 Nsmce3; (RefSeq) non-structural maintenance of chromosomes element 3 homolog K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 138803950 Nsmce4a; (RefSeq) non-structural maintenance of chromosomes element 4 homolog A K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 138806158 Eid3; (RefSeq) EP300-interacting inhibitor of differentiation 3 K22826 EID3; EP300-interacting inhibitor of differentiation 3
E 138832886 Slf1; (RefSeq) SMC5-SMC6 complex localization factor protein 1 isoform X1 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
E 138808858 Slf2; (RefSeq) SMC5-SMC6 complex localization factor protein 2 isoform X1 K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
E 138837599 Simc1; (RefSeq) SUMO-interacting motif-containing protein 1 K28408 SIMC1; SUMO-interacting motif-containing protein 1
D Other HR factors
E 138831154 Eme1; (RefSeq) crossover junction endonuclease EME1 isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 138814459 probable crossover junction endonuclease EME2 K10883 EME2; crossover junction endonuclease EME2
E 138825278 probable crossover junction endonuclease EME2 K10883 EME2; crossover junction endonuclease EME2
E 138833029 Exd2; (RefSeq) exonuclease 3'-5' domain-containing protein 2 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 138818704 crossover junction endonuclease MUS81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 138824322 crossover junction endonuclease MUS81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 138810097 Sem1; (RefSeq) 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 138815754 Swi5; (RefSeq) DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3
E 138808040 Sfr1; (RefSeq) swi5-dependent recombination DNA repair protein 1 homolog isoform X1 K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E 138815008 structure-specific endonuclease subunit SLX1-like isoform X1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 138841716 structure-specific endonuclease subunit SLX1-like isoform X1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 138814579 structure-specific endonuclease subunit SLX4-like isoform X1 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 138825493 structure-specific endonuclease subunit SLX4-like isoform X1 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 138829059 Gen1; (RefSeq) flap endonuclease GEN homolog 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 138804899 spatacsin-like isoform X1 K19026 SPG11; spatacsin
E 138816293 Spg11; (RefSeq) spatacsin isoform X1 K19026 SPG11; spatacsin
E 138809387 zinc finger FYVE domain-containing protein 26-like isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 138833138 Zfyve26; (RefSeq) zinc finger FYVE domain-containing protein 26 isoform X1 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 138816325 Rad51ap1; (RefSeq) RAD51-associated protein 1 isoform X1 K20778 RAD51AP1; RAD51-associated protein 1
E 138841862 Morf4l1; (RefSeq) mortality factor 4-like protein 1 isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1
E 138816957 Samhd1; (RefSeq) deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 138809453 Fignl1; (RefSeq) fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 138805707 Spidr; (RefSeq) DNA repair-scaffolding protein isoform X1 K22806 SPIDR; DNA repair-scaffolding protein
E 138806003 Lratd2; (RefSeq) protein LRATD2 K22810 FAM84B; protein FAM84B
E 138834757 Brat1; (RefSeq) BRCA1-associated ATM activator 1 isoform X1 K23112 BRAT1; BRCA1-associated ATM activator 1
E 138832581 Cfap410; (RefSeq) cilia- and flagella-associated protein 410 K23456 CFAP410; cilla- and flagella-associated protein
E 138807601 hepatoma-derived growth factor-related protein 2-like isoform X1 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 138813940 hepatoma-derived growth factor-related protein 2-like isoform X1 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 138830841 Zswim7; (RefSeq) zinc finger SWIM domain-containing protein 7 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 138813786 Swsap1; (RefSeq) ATPase SWSAP1 K25771 SWSAP1; ATPase SWSAP1
E 138836383 Emsy; (RefSeq) BRCA2-interacting transcriptional repressor EMSY isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 138832568 Hsf2bp; (RefSeq) heat shock factor 2-binding protein K25791 HSF2BP; heat shock factor 2-binding protein
E 138819065 Mms22l; (RefSeq) protein MMS22-like K26125 MMS22L; protein MMS22-like
E 138806095 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 138829625 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 138820563 Bod1l1; (RefSeq) biorientation of chromosomes in cell division protein 1-like 1 isoform X1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 138806007 Parpbp; (RefSeq) PCNA-interacting partner isoform X1 K27412 PARPBP; PCNA-interacting partner
E 138830914 Hrob; (RefSeq) homologous recombination OB-fold protein isoform X1 K27803 HROB; homologous recombination OB-fold protein
E 138816739 Mcm8; (RefSeq) DNA helicase MCM8 K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
E 138822551 Mcm9; (RefSeq) DNA helicase MCM9 isoform X1 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 138811799 Xrcc6; (RefSeq) X-ray repair cross-complementing protein 6 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 138824022 Xrcc5; (RefSeq) X-ray repair cross-complementing protein 5 isoform X1 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 138805709 Prkdc; (RefSeq) DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 138804948 Mre11; (RefSeq) double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 138807895 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 138808202 DNA repair protein RAD50-like isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 138813977 Lig4; (RefSeq) DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 138832910 Xrcc4; (RefSeq) DNA repair protein XRCC4 isoform X1 K10886 XRCC4; DNA-repair protein XRCC4
E 138829539 Nhej1; (RefSeq) non-homologous end-joining factor 1 K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E 138808694 Poll; (RefSeq) DNA polymerase lambda isoform X1 K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 138822057 Polm; (RefSeq) DNA-directed DNA/RNA polymerase mu isoform X1 K03513 POLM; DNA polymerase mu [EC:2.7.7.7]
E 138823136 Polb; (RefSeq) DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 138817843 Aptx; (RefSeq) aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 138815231 Aplf; (RefSeq) aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 138805594 Dclre1c; (RefSeq) protein artemis isoform X1 K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 138828388 Tdp2; (RefSeq) tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 138832105 Smchd1; (RefSeq) structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 138817824 Pwwp3a; (RefSeq) PWWP domain-containing DNA repair factor 3A isoform X1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 138840151 Pwwp3b; (RefSeq) PWWP domain-containing DNA repair factor 3B K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 138840331 PWWP domain-containing DNA repair factor 4-like K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 138816801 Paxx; (RefSeq) protein PAXX K25772 PAXX; protein PAXX
E 138809818 Cyren; (RefSeq) cell cycle regulator of non-homologous end joining K26155 CYREN; cell cycle regulator of non-homologous end joining
E 138816746 Shld1; (RefSeq) shieldin complex subunit 1 isoform X1 K26128 SHLD1; shieldin complex subunit 1
E 138825961 Shld2; (RefSeq) shieldin complex subunit 2 isoform X1 K26129 SHLD2; shieldin complex subunit 2
E 138821076 Bend4; (RefSeq) BEN domain-containing protein 4 K27845 BEND4; BEN domain-containing protein 4
C FA (Fanconi anemia) pathway
D FA core complex
E 138803759 Fanca; (RefSeq) Fanconi anemia group A protein isoform X1 K10888 FANCA; fanconi anemia group A protein
E 138839938 Fancb; (RefSeq) Fanconi anemia group B protein K10889 FANCB; fanconi anemia group B protein
E 138834897 Fancc; (RefSeq) Fanconi anemia group C protein isoform X1 K10890 FANCC; fanconi anemia group C protein
E 138828136 Fance; (RefSeq) Fanconi anemia group E protein isoform X1 K10892 FANCE; fanconi anemia group E protein
E 138834046 Fancf; (RefSeq) Fanconi anemia group F protein K10893 FANCF; fanconi anemia group F protein
E 138818326 Fancg; (RefSeq) Fanconi anemia group G protein isoform X1 K10894 FANCG; fanconi anemia group G protein
E 138829309 Fancl; (RefSeq) E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 138830736 Fancm; (RefSeq) Fanconi anemia group M protein isoform X1 K10896 FANCM; fanconi anemia group M protein
E 138811050 Faap24; (RefSeq) Fanconi anemia core complex-associated protein 24 K10898 FAAP24; fanconi anemia-associated protein
E 138833243 Faap100; (RefSeq) Fanconi anemia core complex-associated protein 100 K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
D FA core complex binding factors
E 138832235 Hes1; (RefSeq) transcription factor HES-1 K06054 HES1; hairy and enhancer of split 1
E 138838163 Cenps; (RefSeq) centromere protein S K11511 APITD1; centromere protein S
E 138833269 Cenpx; (RefSeq) centromere protein X K15360 STRA13; centromere protein X
E 138841179 Ube2t; (RefSeq) ubiquitin-conjugating enzyme E2 T isoform X1 K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 138842096 Blm; (RefSeq) recQ-like DNA helicase BLM isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 138808262 Top3b; (RefSeq) DNA topoisomerase 3-beta-1 isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 138830806 Top3a; (RefSeq) DNA topoisomerase 3-alpha isoform X1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 138836867 Rmi1; (RefSeq) recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
E 138814440 Rmi2; (RefSeq) recQ-mediated genome instability protein 2 K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E 138822692 Fanconi anemia group D2 protein-like K10891 FANCD2; fanconi anemia group D2 protein
E 138824799 Fanconi anemia group D2 protein-like K10891 FANCD2; fanconi anemia group D2 protein
E 138842068 Fanci; (RefSeq) Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 138830896 Brca1; (RefSeq) breast cancer type 1 susceptibility protein isoform X1 K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 138814115 Brca2; (RefSeq) breast cancer type 2 susceptibility protein isoform X1 K08775 BRCA2; breast cancer 2 susceptibility protein
E 138830353 Brip1; (RefSeq) LOW QUALITY PROTEIN: Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 138815057 Palb2; (RefSeq) partner and localizer of BRCA2 isoform X1 K10897 PALB2; partner and localizer of BRCA2
D Other FA pathway factors
E 138842009 Fan1; (RefSeq) fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 138816216 Rad51; (RefSeq) DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 138830597 Rad51c; (RefSeq) DNA repair protein RAD51 homolog 3 isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 138814679 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 138825411 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 138818061 Usp1; (RefSeq) ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 138823948 Wdr48; (RefSeq) WD repeat-containing protein 48 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 138821365 Ppp6c; (RefSeq) serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 138812607 Ppp6r1; (RefSeq) serine/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1 K15499 PPP6R1; serine/threonine-protein phosphatase 6 regulatory subunit 1
E 138811856 Ppp6r2; (RefSeq) serine/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 138818558 Ppp6r3; (RefSeq) serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 138824646 Ankrd28; (RefSeq) serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 138809232 Ankrd44; (RefSeq) serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1 K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 138841955 Ankrd52; (RefSeq) serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
D Ubiquitin ligases
E 138828111 Rnf8; (RefSeq) E3 ubiquitin-protein ligase RNF8 isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 138832256 Rnf168; (RefSeq) E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 138836400 Rnf169; (RefSeq) E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 138841973 Herc2; (RefSeq) E3 ubiquitin-protein ligase HERC2 isoform X1 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 138813221 Wrap53; (RefSeq) telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
E 138822344 Tprn; (RefSeq) taperin K24164 TPRN; taperin
E 138804784 Zcwpw1; (RefSeq) zinc finger CW-type PWWP domain protein 1 isoform X1 K24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1
E 138840739 Wdr70; (RefSeq) WD repeat-containing protein 70 isoform X1 K24752 WDR70; WD repeat-containing protein 70
E 138816289 Wdr76; (RefSeq) WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
E 138806615 abasic site processing protein HMCES-like K28434 HMCES; abasic site processing protein HMCES
E 138824880 abasic site processing protein HMCES-like K28434 HMCES; abasic site processing protein HMCES
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 138828035 Polh; (RefSeq) DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 138831980 Poli; (RefSeq) DNA polymerase iota isoform X1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 138833017 DNA polymerase kappa-like isoform X1 K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 138834385 DNA polymerase kappa-like isoform X1 K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 138804307 Rev1; (RefSeq) DNA repair protein REV1 isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 138828665 Rev3l; (RefSeq) DNA polymerase zeta catalytic subunit isoform X1 K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
D 138826512 Poln; (RefSeq) DNA polymerase nu isoform X1 K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 138840101 Ube2a; (RefSeq) ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 138807920 Ube2b; (RefSeq) ubiquitin-conjugating enzyme E2 B isoform X1 K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 138820609 ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 138824777 E3 ubiquitin-protein ligase RAD18-like isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 138840887 E3 ubiquitin-protein ligase RAD18-like isoform X1 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 138804504 helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 138837647 helicase-like transcription factor isoform X1 K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 138805711 Ube2v2; (RefSeq) ubiquitin-conjugating enzyme E2 variant 2 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 138805247 Ube2n; (RefSeq) ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 138816751 Pcna; (RefSeq) proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 138806007 Parpbp; (RefSeq) PCNA-interacting partner isoform X1 K27412 PARPBP; PCNA-interacting partner
D 138810832 Sprtn; (RefSeq) DNA-dependent metalloprotease SPRTN isoform X1 K24051 SPRTN; SprT-like domain-contaning protein Spartan
B Check point factors
C Rad9-Hus1-Rad1 complex
D 138818824 cell cycle checkpoint control protein RAD9A-like isoform X1 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 138824361 cell cycle checkpoint control protein RAD9A-like isoform X1 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 138826401 cell cycle checkpoint control protein RAD9B-like isoform X1 K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 138840922 cell cycle checkpoint control protein RAD9B-like isoform X1 K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 138822041 Hus1; (RefSeq) checkpoint protein HUS1 isoform X1 K10903 HUS1; HUS1 checkpoint protein
D 138839575 checkpoint protein HUS1-like isoform X1 K10903 HUS1; HUS1 checkpoint protein
D 138839576 checkpoint protein HUS1-like isoform X1 K10903 HUS1; HUS1 checkpoint protein
D 138839864 checkpoint protein HUS1-like K10903 HUS1; HUS1 checkpoint protein
D 138837775 Hus1b; (RefSeq) checkpoint protein HUS1B K10996 HUS1B; checkpoint protein HUS1B
D 138840717 Rad1; (RefSeq) cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 138832972 Rad17; (RefSeq) cell cycle checkpoint protein RAD17 isoform X1 K06662 HRAD17; cell cycle checkpoint protein
D 138832214 Rfc4; (RefSeq) replication factor C subunit 4 isoform X1 K10755 RFC2_4; replication factor C subunit 2/4
D 138836895 Rfc2; (RefSeq) replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 138807778 replication factor C subunit 5 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
D 138814107 Rfc3; (RefSeq) replication factor C subunit 3 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
D 138837698 replication factor C subunit 5-like isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 138840717 Rad1; (RefSeq) cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 138842084 Timeless; (RefSeq) protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 138808867 Tipin; (RefSeq) TIMELESS-interacting protein isoform X1 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 138818080 Clspn; (RefSeq) claspin isoform X1 K25773 CLSPN; claspin
C Triple T complex
D 138814679 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 138825411 telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 138804061 Tti1; (RefSeq) TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 138823182 Tti2; (RefSeq) TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 138828243 Bag6; (RefSeq) large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 138817030 Ubl4b; (RefSeq) ubiquitin-like protein 4B K23388 UBL4; ubiquitin-like protein 4
D 138839961 Ubl4a; (RefSeq) ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 138834729 Get4; (RefSeq) Golgi to ER traffic protein 4 homolog isoform X1 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 138816042 Atr; (RefSeq) serine/threonine-protein kinase ATR isoform X1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 138824034 Atrip; (RefSeq) ATR-interacting protein isoform X1 K10905 ATRIP; ATR interacting protein
D 138829957 LOW QUALITY PROTEIN: ATR-interacting protein-like K10905 ATRIP; ATR interacting protein
D 138821335 serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 138838810 serine-protein kinase ATM-like K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 138813222 Tp53; (RefSeq) cellular tumor antigen p53 K04451 TP53; tumor protein p53
D 138821385 Chek1; (RefSeq) serine/threonine-protein kinase Chk1 isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 138838852 serine/threonine-protein kinase Chk1 isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 138808407 Chek2; (RefSeq) serine/threonine-protein kinase Chk2 isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 138824040 Cdc25a; (RefSeq) M-phase inducer phosphatase 1 isoform X1 K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
D 138816780 Cdc25b; (RefSeq) M-phase inducer phosphatase 2 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 138837369 Cdc25c; (RefSeq) M-phase inducer phosphatase 3 isoform X1 K05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]
D 138805198 Ywhab; (RefSeq) 14-3-3 protein beta/alpha K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 138805903 Ywhaz; (RefSeq) 14-3-3 protein zeta/delta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 138811397 14-3-3 protein theta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 138822463 Ywhaq; (RefSeq) 14-3-3 protein theta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 138808351 Ywhah; (RefSeq) 14-3-3 protein eta K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 138834863 Ywhag; (RefSeq) 14-3-3 protein gamma K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 138830754 Ywhae; (RefSeq) 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon
D 138834050 Nav2; (RefSeq) neuron navigator 2 isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 138836518 Wee1; (RefSeq) wee1-like protein kinase isoform X1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 138813209 Per1; (RefSeq) period circadian protein homolog 1 isoform X1 K21944 PER1; period circadian protein 1
D 138814575 Per2; (RefSeq) period circadian protein homolog 2 isoform X1 K02633 PER2; period circadian protein 2
D 138838135 Per3; (RefSeq) period circadian protein homolog 3 isoform X1 K21945 PER3; period circadian protein 3
D 138828264 Mdc1; (RefSeq) mediator of DNA damage checkpoint protein 1 isoform X1 K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 138840116 Pls3; (RefSeq) plastin-3 isoform X1 K17336 PLS3; plastin-3
D 138842064 apoptosis-enhancing nuclease-like isoform X1 K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 138803413 serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 138823630 serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 138805022 serine/threonine-protein kinase Nek5-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 138812165 serine/threonine-protein kinase Nek5-like isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 138823298 Nek1; (RefSeq) serine/threonine-protein kinase Nek1 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 138824629 Nek4; (RefSeq) serine/threonine-protein kinase Nek4 isoform X1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 138824688 Nek10; (RefSeq) serine/threonine-protein kinase Nek10 isoform X1 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 138815973 Nek11; (RefSeq) serine/threonine-protein kinase Nek11 isoform X1 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D 138832498 Donson; (RefSeq) protein downstream neighbor of Son K22422 DONSON; protein downstream neighbor of Son
D 138813794 Kank2; (RefSeq) KN motif and ankyrin repeat domain-containing protein 2 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 138813877 Kank3; (RefSeq) KN motif and ankyrin repeat domain-containing protein 3 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 138817961 Kank4; (RefSeq) KN motif and ankyrin repeat domain-containing protein 4 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 138836971 Kank1; (RefSeq) KN motif and ankyrin repeat domain-containing protein 1 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 138805816 Chmp4c; (RefSeq) charged multivesicular body protein 4c isoform X1 K24782 CHMP4C; charged multivesicular body protein 4C
D 138807051 vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 138815362 Vps4a; (RefSeq) vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 138831942 Vps4b; (RefSeq) vacuolar protein sorting-associated protein 4B K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 138816218 Zfyve19; (RefSeq) abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 138827601 Sde2; (RefSeq) splicing regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 138831849 Polq; (RefSeq) DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 138813327 Mybbp1a; (RefSeq) myb-binding protein 1A K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 138823252 Primpol; (RefSeq) DNA-directed primase/polymerase protein isoform X1 K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 138823937 Trex1; (RefSeq) three-prime repair exonuclease 1 K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D 138829956 three-prime repair exonuclease 1-like K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D 138839295 Trex2; (RefSeq) three prime repair exonuclease 2 K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
D 138803889 Dclre1a; (RefSeq) DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D 138803470 LOW QUALITY PROTEIN: exonuclease V-like K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 138837839 exonuclease V-like isoform X1 K17815 EXO5; exonuclease V [EC:3.1.-.-]
D 138833231 Endov; (RefSeq) endonuclease V K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 138828165 Zranb3; (RefSeq) DNA annealing helicase and endonuclease ZRANB3 isoform X1 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D 138817817 Ankle1; (RefSeq) ankyrin repeat and LEM domain-containing protein 1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 138821062 Helq; (RefSeq) helicase POLQ-like isoform X1 K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 138834900 Ercc6l2; (RefSeq) DNA excision repair protein ERCC-6-like 2 isoform X1 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 138833846 Prpf19; (RefSeq) pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 138828017 Cdc5l; (RefSeq) cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 138816567 Bcas2; (RefSeq) pre-mRNA-splicing factor SPF27 isoform X1 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 138826894 Plrg1; (RefSeq) pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 138834750 oxidized purine nucleoside triphosphate hydrolase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 138834751 oxidized purine nucleoside triphosphate hydrolase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 138823337 Nudt18; (RefSeq) 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 138816710 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 138830168 Dut; (RefSeq) deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 138836454 Rrm1; (RefSeq) ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 138805911 Rrm2b; (RefSeq) ribonucleoside-diphosphate reductase subunit M2 B isoform X1 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 138822469 Rrm2; (RefSeq) ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 138819875 Mgmt; (RefSeq) methylated-DNA--protein-cysteine methyltransferase isoform X1 K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 138821665 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E 138808520 Ung; (RefSeq) uracil-DNA glycosylase isoform X1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 138829806 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 138816420 Smug1; (RefSeq) single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 138825331 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 138825368 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 138803405 adenine DNA glycosylase-like isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 138823622 adenine DNA glycosylase-like isoform X1 K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 138814491 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E 138825315 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 138809869 Ssbp1; (RefSeq) single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 138809869 Ssbp1; (RefSeq) single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 138816710 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 138830168 Dut; (RefSeq) deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025