+C Two-component system KO
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Two-Component System - Desulfosporosinus meridiei
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C Desmer_3834 signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C Desmer_1982 signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C Desmer_2496 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C Desmer_3835 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C Desmer_4170 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
C Desmer_4428 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C Desmer_0442 osmosensitive K+ channel histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C Desmer_2979 osmosensitive K+ channel histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C Desmer_0443 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C Desmer_3962 signal transduction histidine kinase K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C Desmer_3711 signal transduction histidine kinase K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C Desmer_3712 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07775 resD; two-component system, OmpR family, response regulator ResD
C Desmer_3963 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07775 resD; two-component system, OmpR family, response regulator ResD
C Desmer_2989 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
C Desmer_1852 signal transduction histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
C Desmer_1851 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
C Desmer_1787 histidine kinase K18350 vanSC; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
C Desmer_1786 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K18349 vanRC; two-component system, OmpR family, response regulator VanR
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
C Desmer_3572 signal transduction histidine kinase K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
C Desmer_3571 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K18941 arlR; two-component system, OmpR family, response regulator ArlR
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
C Desmer_1388 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR/SpaR
B Unclassified
C Desmer_2852 signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C Desmer_2853 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K02483 K02483; two-component system, OmpR family, response regulator
C Desmer_3969 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K02483 K02483; two-component system, OmpR family, response regulator
C Desmer_1981 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K02483 K02483; two-component system, OmpR family, response regulator
C Desmer_2010 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
C Desmer_2021 histidine kinase K07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
C Desmer_4125 signal transduction histidine kinase K07680 comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]
C Desmer_2022 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07691 comA; two-component system, NarL family, competent response regulator ComA
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
C Desmer_2528 histidine kinase K07777 degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]
C Desmer_2527 response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07692 degU; two-component system, NarL family, response regulator DegU
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
C Desmer_2725 signal transduction histidine kinase K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
C Desmer_0754 PAS domain S-box K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
C Desmer_1154 PAS domain S-box K02491 kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]
C Desmer_3340 signal transduction histidine kinase, nitrogen specific K07698 kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
C Desmer_1319 PAS domain S-box K07698 kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
C Desmer_0308 signal transduction histidine kinase K07698 kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]
C Desmer_4417 histidine kinase K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Desmer_2141 PAS domain S-box K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Desmer_2257 PAS domain S-box K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Desmer_1951 PAS domain S-box K13533 kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]
C Desmer_3121 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C Desmer_1950 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C Desmer_1954 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C Desmer_4582 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02490 spo0F; two-component system, response regulator, stage 0 sporulation protein F
C Desmer_2644 response regulator receiver protein K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
C Desmer_1042 sporulation transcription factor Spo0A K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
C Desmer_1139 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
C Desmer_4409 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain K11692 K11692; two-component system, CitB family, response regulator DctR
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C Desmer_1086 putative regulator of cell autolysis K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Desmer_3174 putative regulator of cell autolysis K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Desmer_2328 histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Desmer_1087 response regulator of the LytR/AlgR family K02477 K02477; two-component system, LytTR family, response regulator
C Desmer_3173 response regulator of the LytR/AlgR family K02477 K02477; two-component system, LytTR family, response regulator
C Desmer_1346 response regulator containing CheY-like receiver and SARP domains K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
C Desmer_0645 signal transduction histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C Desmer_0675 histidine kinase,HAMP domain-containing protein,histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
B AtoS-AtoC (cPHB biosynthesis)
C Desmer_3799 PAS/PAC sensor signal transduction histidine kinase K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
C Desmer_3798 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 atoC; two-component system, NtrC family, response regulator AtoC
C Desmer_3468 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 atoC; two-component system, NtrC family, response regulator AtoC
C Desmer_0644 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 atoC; two-component system, NtrC family, response regulator AtoC
C Desmer_0674 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 atoC; two-component system, NtrC family, response regulator AtoC
C Desmer_2360 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 atoC; two-component system, NtrC family, response regulator AtoC
C Desmer_1693 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C Desmer_3469 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C Desmer_3614 histidine kinase,HAMP domain-containing protein,histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C Desmer_0421 signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C Desmer_3922 chemotaxis protein histidine kinase-like protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C Desmer_1020 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C Desmer_3907 response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C Desmer_3920 chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C Desmer_4075 chemotaxis signal transduction protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
C Desmer_3257 putative signal transduction protein with a C-terminal ATPase domain K07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]
C Desmer_2319 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 yesN; two-component system, response regulator YesN
C Desmer_4374 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 yesN; two-component system, response regulator YesN
C Desmer_3256 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 yesN; two-component system, response regulator YesN
C Desmer_2206 response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 yesN; two-component system, response regulator YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
C Desmer_1745 signal transduction histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
C Desmer_0886 response regulator with putative antiterminator output domain K22010 pdtaR; two-component system, response regulator PdtaR
C Desmer_1746 response regulator with putative antiterminator output domain K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
C Desmer_1345 putative regulator of cell autolysis K19694 chiS; two-component system, sensor histidine kinase ChiS
C Desmer_3567 signal transduction histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C Desmer_3594 signal transduction histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023