+F Repair protein KO
#
DNA Repair and Recombination Proteins - Daphnia pulex (common water flea)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DAPPUDRAFT_216243 hypothetical protein K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D DAPPUDRAFT_327399 PL2; DNA photolyase 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E DAPPUDRAFT_95942 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E DAPPUDRAFT_43853 hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E DAPPUDRAFT_221022 hypothetical protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E DAPPUDRAFT_128395 hypothetical protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E DAPPUDRAFT_314361 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E DAPPUDRAFT_35863 hypothetical protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E DAPPUDRAFT_313422 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E DAPPUDRAFT_57329 hypothetical protein K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E DAPPUDRAFT_193197 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E DAPPUDRAFT_305561 hypothetical protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F DAPPUDRAFT_317527 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F DAPPUDRAFT_299981 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
F DAPPUDRAFT_301562 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F DAPPUDRAFT_227571 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F DAPPUDRAFT_308600 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F DAPPUDRAFT_7359 hypothetical protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E DAPPUDRAFT_309373 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E DAPPUDRAFT_33887 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E DAPPUDRAFT_47502 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E DAPPUDRAFT_304798 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E DAPPUDRAFT_310135 hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E DAPPUDRAFT_96117 hypothetical protein K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E DAPPUDRAFT_46356 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E DAPPUDRAFT_232871 hypothetical protein K10802 HMGB1; high mobility group protein B1
E DAPPUDRAFT_55885 hypothetical protein K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F DAPPUDRAFT_306329 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F DAPPUDRAFT_299929 hypothetical protein K10839 RAD23; UV excision repair protein RAD23
F DAPPUDRAFT_442803 CEN; centrin K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F DAPPUDRAFT_60651 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_65504 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_65506 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_40730 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_65509 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_302594 hypothetical protein K10609 CUL4; cullin 4
F DAPPUDRAFT_303245 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F DAPPUDRAFT_39221 hypothetical protein K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F DAPPUDRAFT_306846 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_70163 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_67765 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_328199 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_319346 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_319347 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_244672 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_52186 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_304478 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F DAPPUDRAFT_102782 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F DAPPUDRAFT_313021 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F DAPPUDRAFT_306425 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F DAPPUDRAFT_308488 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F DAPPUDRAFT_64901 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F DAPPUDRAFT_308561 hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F DAPPUDRAFT_191687 hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F DAPPUDRAFT_231046 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F DAPPUDRAFT_230475 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F DAPPUDRAFT_230556 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F DAPPUDRAFT_231106 hypothetical protein K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F DAPPUDRAFT_60651 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_65504 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_65506 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_40730 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_65509 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F DAPPUDRAFT_302594 hypothetical protein K10609 CUL4; cullin 4
F DAPPUDRAFT_303245 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F DAPPUDRAFT_300153 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F DAPPUDRAFT_231974 DNA excision repair protein ERCC-6-like protein K10841 ERCC6; DNA excision repair protein ERCC-6
F DAPPUDRAFT_213666 hypothetical protein K23720 UVSSA; UV-stimulated scaffold protein A
D TFIIH complex
E DAPPUDRAFT_300803 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E DAPPUDRAFT_324413 hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E DAPPUDRAFT_328341 hypothetical protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E DAPPUDRAFT_301632 hypothetical protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E DAPPUDRAFT_317251 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E DAPPUDRAFT_224195 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E DAPPUDRAFT_210868 hypothetical protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E DAPPUDRAFT_328340 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E DAPPUDRAFT_213779 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E DAPPUDRAFT_193044 cyclin H-like protein K06634 CCNH; cyclin H
E DAPPUDRAFT_205778 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E DAPPUDRAFT_226387 hypothetical protein K10739 RFA2; replication factor A2
E DAPPUDRAFT_239719 hypothetical protein K10739 RFA2; replication factor A2
E DAPPUDRAFT_220332 hypothetical protein K10740 RPA3; replication factor A3
D Other NER factors
E DAPPUDRAFT_220521 hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E DAPPUDRAFT_61546 hypothetical protein K10849 ERCC1; DNA excision repair protein ERCC-1
E DAPPUDRAFT_331812 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E DAPPUDRAFT_304798 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E DAPPUDRAFT_221700 hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E DAPPUDRAFT_228373 hypothetical protein K03869 CUL3; cullin 3
E DAPPUDRAFT_307204 hypothetical protein K10612 CUL5; cullin 5
E DAPPUDRAFT_203467 hypothetical protein K03872 ELOC; elongin-C
E DAPPUDRAFT_226482 hypothetical protein K03873 ELOB; elongin-B
E DAPPUDRAFT_221473 hypothetical protein K15076 ELOA; elongin-A
E DAPPUDRAFT_312181 hypothetical protein K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E DAPPUDRAFT_325677 mismatch repair ATPase Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E DAPPUDRAFT_327819 putative MSH3, mismatch repair ATPase K08736 MSH3; DNA mismatch repair protein MSH3
E DAPPUDRAFT_336969 hypothetical protein K08736 MSH3; DNA mismatch repair protein MSH3
E DAPPUDRAFT_303932 putative MSH6, mismatch repair ATPase K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E DAPPUDRAFT_308451 putative MLH1, MutL protein 1 K08734 MLH1; DNA mismatch repair protein MLH1
E DAPPUDRAFT_311334 putative PMS1, postmeiotic segregation increased 2 protein K10858 PMS2; DNA mismatch repair protein PMS2
E DAPPUDRAFT_324171 putative MLH3, MutL protein 3 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E DAPPUDRAFT_317527 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E DAPPUDRAFT_299981 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
E DAPPUDRAFT_301562 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E DAPPUDRAFT_226387 hypothetical protein K10739 RFA2; replication factor A2
E DAPPUDRAFT_239719 hypothetical protein K10739 RFA2; replication factor A2
E DAPPUDRAFT_220332 hypothetical protein K10740 RPA3; replication factor A3
D RFC (replication factor C)
E DAPPUDRAFT_318220 hypothetical protein K10754 RFC1; replication factor C subunit 1
E DAPPUDRAFT_303531 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E DAPPUDRAFT_301682 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E DAPPUDRAFT_202808 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
E DAPPUDRAFT_190647 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E DAPPUDRAFT_309373 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E DAPPUDRAFT_110118 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E DAPPUDRAFT_232871 hypothetical protein K10802 HMGB1; high mobility group protein B1
E DAPPUDRAFT_304798 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E DAPPUDRAFT_308645 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E DAPPUDRAFT_188962 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E DAPPUDRAFT_322547 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E DAPPUDRAFT_327734 hypothetical protein K10867 NBN; nibrin
D BRCA1-core complex
E DAPPUDRAFT_102038 hypothetical protein K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E DAPPUDRAFT_308966 hypothetical protein K12173 BRE; BRCA1-A complex subunit BRE
E DAPPUDRAFT_229214 hypothetical protein K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E DAPPUDRAFT_48831 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E DAPPUDRAFT_311920 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E DAPPUDRAFT_300415 hypothetical protein K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
E DAPPUDRAFT_301523 hypothetical protein K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E DAPPUDRAFT_188962 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E DAPPUDRAFT_322547 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E DAPPUDRAFT_327734 hypothetical protein K10867 NBN; nibrin
D BRCA complex
E DAPPUDRAFT_303344 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
E DAPPUDRAFT_299714 hypothetical protein K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E DAPPUDRAFT_299714 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E DAPPUDRAFT_242313 RAD51C; putative RAD51C K10870 RAD51L2; RAD51-like protein 2
E DAPPUDRAFT_300755 putative RAD51D K10871 RAD51L3; RAD51-like protein 3
E DAPPUDRAFT_5268 putative XRCC3 K10879 XRCC2; DNA-repair protein XRCC2
D Rad52 family proteins
E DAPPUDRAFT_100705 hypothetical protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E DAPPUDRAFT_306273 RAD54, DNA repair and recombination protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E DAPPUDRAFT_332470 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E DAPPUDRAFT_101478 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E DAPPUDRAFT_106066 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E DAPPUDRAFT_207797 RAD54B meiotic recombination protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E DAPPUDRAFT_347584 RecQ1; RecQ1-like protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E DAPPUDRAFT_347587 DNA helicase bloom's syndrome protein A K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E DAPPUDRAFT_347585 DNA helicase RecQ4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E DAPPUDRAFT_347587 DNA helicase bloom's syndrome protein A K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E DAPPUDRAFT_324341 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E DAPPUDRAFT_313782 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
E DAPPUDRAFT_299961 hypothetical protein K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E DAPPUDRAFT_226387 hypothetical protein K10739 RFA2; replication factor A2
E DAPPUDRAFT_239719 hypothetical protein K10739 RFA2; replication factor A2
E DAPPUDRAFT_220332 hypothetical protein K10740 RPA3; replication factor A3
D Protein phosphatase 4
E DAPPUDRAFT_209708 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E DAPPUDRAFT_59343 hypothetical protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E DAPPUDRAFT_229122 hypothetical protein K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E DAPPUDRAFT_62030 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E DAPPUDRAFT_226104 putative SMC5, structural maintenance of chromosome protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E DAPPUDRAFT_103378 putative SMC6, structural maintenance of chromosome protein 6, copy A K22804 SMC6; structural maintenance of chromosomes protein 6
E DAPPUDRAFT_224715 putative SMC6, structural maintenance of chromosome protein 6, copy B K22804 SMC6; structural maintenance of chromosomes protein 6
E DAPPUDRAFT_305975 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E DAPPUDRAFT_307540 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E DAPPUDRAFT_211258 hypothetical protein K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E DAPPUDRAFT_307362 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E DAPPUDRAFT_95947 hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E DAPPUDRAFT_305758 hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E DAPPUDRAFT_325261 hypothetical protein K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E DAPPUDRAFT_325251 hypothetical protein K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E DAPPUDRAFT_341412 hypothetical protein K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E DAPPUDRAFT_304957 hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E DAPPUDRAFT_327432 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E DAPPUDRAFT_306753 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E DAPPUDRAFT_54979 hypothetical protein K19026 SPG11; spatacsin
E DAPPUDRAFT_239388 hypothetical protein K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E DAPPUDRAFT_299826 hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E DAPPUDRAFT_322816 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E DAPPUDRAFT_95973 hypothetical protein K22806 SPIDR; DNA repair-scaffolding protein
E DAPPUDRAFT_314348 hypothetical protein K23112 BRAT1; BRCA1-associated ATM activator 1
E DAPPUDRAFT_308728 hypothetical protein K23112 BRAT1; BRCA1-associated ATM activator 1
E DAPPUDRAFT_56378 hypothetical protein K23456 CFAP410; cilla- and flagella-associated protein
E DAPPUDRAFT_322466 hypothetical protein K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E DAPPUDRAFT_240841 hypothetical protein K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E DAPPUDRAFT_332332 hypothetical protein K26125 MMS22L; protein MMS22-like
E DAPPUDRAFT_62661 hypothetical protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E DAPPUDRAFT_40467 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E DAPPUDRAFT_333161 hypothetical protein K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E DAPPUDRAFT_188962 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E DAPPUDRAFT_322547 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E DAPPUDRAFT_323605 hypothetical protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E DAPPUDRAFT_221227 hypothetical protein K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E DAPPUDRAFT_300508 hypothetical protein K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
D Other NHEJ factors
E DAPPUDRAFT_96117 hypothetical protein K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E DAPPUDRAFT_49525 hypothetical protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E DAPPUDRAFT_225352 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E DAPPUDRAFT_320138 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E DAPPUDRAFT_305861 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
E DAPPUDRAFT_301633 hypothetical protein K10888 FANCA; fanconi anemia group A protein
E DAPPUDRAFT_215303 hypothetical protein K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E DAPPUDRAFT_303840 hypothetical protein K15360 STRA13; centromere protein X
D Bloom's syndrome complex (BTR)
E DAPPUDRAFT_347587 DNA helicase bloom's syndrome protein A K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E DAPPUDRAFT_324341 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E DAPPUDRAFT_313782 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
E DAPPUDRAFT_299961 hypothetical protein K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E DAPPUDRAFT_312346 hypothetical protein K10891 FANCD2; fanconi anemia group D2 protein
E DAPPUDRAFT_309623 hypothetical protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E DAPPUDRAFT_303344 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
E DAPPUDRAFT_48831 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E DAPPUDRAFT_311920 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E DAPPUDRAFT_302110 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E DAPPUDRAFT_299714 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E DAPPUDRAFT_242313 RAD51C; putative RAD51C K10870 RAD51L2; RAD51-like protein 2
E DAPPUDRAFT_1144 hypothetical protein K11137 TELO2; telomere length regulation protein
E DAPPUDRAFT_333124 hypothetical protein K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E DAPPUDRAFT_195062 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E DAPPUDRAFT_72831 hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E DAPPUDRAFT_303396 hypothetical protein K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E DAPPUDRAFT_310134 hypothetical protein K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
D Ubiquitin ligases
E DAPPUDRAFT_324600 hypothetical protein K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E DAPPUDRAFT_326474 hypothetical protein K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E DAPPUDRAFT_101032 hypothetical protein K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E DAPPUDRAFT_252196 hypothetical protein K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E DAPPUDRAFT_310691 hypothetical protein K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E DAPPUDRAFT_50378 hypothetical protein K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E DAPPUDRAFT_302373 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E DAPPUDRAFT_308645 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D DAPPUDRAFT_228708 hypothetical protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D DAPPUDRAFT_3781 hypothetical protein K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D DAPPUDRAFT_31218 hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D DAPPUDRAFT_324417 hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D DAPPUDRAFT_303502 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D DAPPUDRAFT_299959 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D DAPPUDRAFT_47484 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D DAPPUDRAFT_299912 hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D DAPPUDRAFT_309332 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D DAPPUDRAFT_309373 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D DAPPUDRAFT_49760 hypothetical protein K24051 SPRTN; SprT-like domain-contaning protein Spartan
B Check point factors
C Rad9-Hus1-Rad1 complex
D DAPPUDRAFT_210503 hypothetical protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D DAPPUDRAFT_326077 hypothetical protein K10903 HUS1; HUS1 checkpoint protein
C HRAD17(Rad24)-RFC complex
D DAPPUDRAFT_113048 hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D DAPPUDRAFT_303531 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D DAPPUDRAFT_301682 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D DAPPUDRAFT_202808 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D DAPPUDRAFT_190647 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
D DAPPUDRAFT_382 putative TIMEOUT/TIM-2 protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D DAPPUDRAFT_307343 hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D DAPPUDRAFT_311226 hypothetical protein K25773 CLSPN; claspin
C Triple T complex
D DAPPUDRAFT_1144 hypothetical protein K11137 TELO2; telomere length regulation protein
D DAPPUDRAFT_234874 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
D DAPPUDRAFT_325742 hypothetical protein K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D DAPPUDRAFT_188776 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
D DAPPUDRAFT_62606 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D DAPPUDRAFT_321001 ATM/Rad3 and Mei-41-like protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D DAPPUDRAFT_311533 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D DAPPUDRAFT_43327 hypothetical protein K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D DAPPUDRAFT_333806 hypothetical protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D DAPPUDRAFT_300413 hypothetical protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D DAPPUDRAFT_307391 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D DAPPUDRAFT_326737 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D DAPPUDRAFT_222417 hypothetical protein K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D DAPPUDRAFT_309101 hypothetical protein K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D DAPPUDRAFT_322497 PER; hypothetical protein K02633 PER2; period circadian protein 2
D DAPPUDRAFT_309082 hypothetical protein K17336 PLS3; plastin-3
D DAPPUDRAFT_24132 hypothetical protein K22422 DONSON; protein downstream neighbor of Son
D DAPPUDRAFT_98029 hypothetical protein K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D DAPPUDRAFT_209675 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D DAPPUDRAFT_225033 hypothetical protein K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D DAPPUDRAFT_227204 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D DAPPUDRAFT_312857 hypothetical protein K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D DAPPUDRAFT_300422 hypothetical protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D DAPPUDRAFT_301610 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D DAPPUDRAFT_327373 hypothetical protein K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D DAPPUDRAFT_312568 hypothetical protein K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D DAPPUDRAFT_312570 hypothetical protein K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D DAPPUDRAFT_105157 hypothetical protein K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D DAPPUDRAFT_105158 hypothetical protein K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D DAPPUDRAFT_16784 hypothetical protein K10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]
D DAPPUDRAFT_41973 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D DAPPUDRAFT_317592 hypothetical protein K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D DAPPUDRAFT_328008 hypothetical protein K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D DAPPUDRAFT_54711 hypothetical protein K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
D DAPPUDRAFT_62611 hypothetical protein K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
D DAPPUDRAFT_70389 hypothetical protein K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D DAPPUDRAFT_320958 hypothetical protein K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D DAPPUDRAFT_303758 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D DAPPUDRAFT_311294 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D DAPPUDRAFT_303553 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D DAPPUDRAFT_306869 hypothetical protein K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D DAPPUDRAFT_316258 hypothetical protein K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D DAPPUDRAFT_202142 hypothetical protein K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D DAPPUDRAFT_211094 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D DAPPUDRAFT_302612 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D DAPPUDRAFT_306462 hypothetical protein K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D DAPPUDRAFT_327399 PL2; DNA photolyase 2 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E DAPPUDRAFT_95942 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E DAPPUDRAFT_128395 hypothetical protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E DAPPUDRAFT_221022 hypothetical protein K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E DAPPUDRAFT_314361 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E DAPPUDRAFT_193197 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E DAPPUDRAFT_62500 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D DAPPUDRAFT_62500 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D DAPPUDRAFT_211094 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024