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Transfer RNA Biogenesis - Danio rerio (zebrafish)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D 799016 pop1; ribonucleases P/MRP protein subunit POP1 K01164 POP1; ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5]
D 553787 pop4; ribonuclease P protein subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D 541421 pop5; ribonuclease P/MRP protein subunit POP5 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D 541352 rpp30; ribonuclease P protein subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D 445136 rpp21; ribonuclease P protein subunit p21 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D 553721 rpp14; ribonuclease P protein subunit p14 K14529 RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]
D 100004610 pop7; ribonuclease P protein subunit p20 K14527 RPP20; ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5]
D 100000532 rpp25a; ribonuclease P protein subunit p25a K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 436813 rpp25l; ribonuclease P protein subunit p25-like protein K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 101885168 rpp25b; ribonuclease P protein subunit p25b K14525 RPP25; ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5]
D 436798 rpp38; ribonuclease P protein subunit p38 K14523 RPP38; ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5]
D 415238 rpp40; ribonuclease P protein subunit p40 K14530 RPP40; ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D 445109 elac1; zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 492652 elac2; zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 791890 rnaset2; ribonuclease T2 precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 553485 rnaset2l; ribonuclease T2-like precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 570247 ptcd1; pentatricopeptide repeat-containing protein 1, mitochondrial isoform X1 K17710 PTCD1; pentatricopeptide repeat domain-containing protein 1
C CCA adding factors
D 415249 trnt1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
D 767713 tsen2; tRNA-splicing endonuclease subunit Sen2 K15322 TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]
D 565995 tsen34; tRNA-splicing endonuclease subunit Sen34 isoform 1 K15323 TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]
D 100005064 tsen15; tRNA-splicing endonuclease subunit Sen15 K15324 TSEN15; tRNA-splicing endonuclease subunit Sen15
D 553550 tsen54; tRNA-splicing endonuclease subunit Sen54 K15326 TSEN54; tRNA-splicing endonuclease subunit Sen54
C tRNA splicing ligase complex
D 406376 rtcb; RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D 553393 si:dkeyp-118h3.6; ashwin K15432 ASW; ashwin
D 393240 rtraf; RNA transcription, translation and transport factor protein K15433 CGI99; RLL motif containing protein 1
D 780841 fam98b; protein FAM98B K15434 FAM98B; protein FAM98B
D 556790 ddx1; ATP-dependent RNA helicase DDX1 K13177 DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]
D 550382 zbtb8os; protein archease K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
D 503604 trpt1; tRNA 2'-phosphotransferase 1 K10669 TRPT1; 2'-phosphotransferase [EC:2.7.1.160]
B tRNA transport factors
C tRNA export factors
D 30572 ran; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
D 558020 xpot; exportin-T K14288 XPOT; exportin-T
D 561138 xpo1b; exportin-1 K14290 XPO1; exportin-1
D 558395 xpo1a; exportin-1 K14290 XPO1; exportin-1
D 558662 xpo5; exportin-5 K14289 XPO5; exportin-5
D 336334 eef1a1a; elongation factor 1-alpha 1a K03231 EEF1A; elongation factor 1-alpha
D 30516 eef1a1l1; elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D 436644 eef1a2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
D 100004503 eef1a1b; elongation factor 1-alpha 1b K03231 EEF1A; elongation factor 1-alpha
D 664756 eef1a1l2; eukaryotic translation elongation factor 1 alpha 1, like 2 K03231 EEF1A; elongation factor 1-alpha
D 407641 eef1a1l3; Elongation factor 1-alpha-like K03231 EEF1A; elongation factor 1-alpha
D 793792 scyl1; N-terminal kinase-like protein K08876 SCYL1; SCY1-like protein 1
D 378721 gtpbp1; GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
D 402863 gtpbp1l; GTP binding protein 1, like K24887 GTPBP1; GTP-binding protein 1
C tRNA import factors
D 394062 tnpo3; transportin-3 K15436 TRPO3; transportin-3
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 562037 eprs1; bifunctional glutamate/proline--tRNA ligase K14163 EPRS; bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
D 751732 ears2; nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial precursor K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 325494 pars2; probable proline--tRNA ligase, mitochondrial K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D 334393 iars1; isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100001219 iars2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100126021 lars2; probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 569778 larsb; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 338183 mars1; methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 566565 mars2; methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 394188 qars1; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 337070 rars1; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 393589 rars2; probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 280647 kars1; lysine--tRNA ligase isoform 1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 324025 dars1; aspartate--tRNA ligase, cytoplasmic K22503 DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 571144 dars2; aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 562232 aimp1a; aminoacyl tRNA synthase complex-interacting multifunctional protein 1a K15437 AIMP1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1
D 406647 aimp2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2 K15438 AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
D 565440 eef1e1; eukaryotic translation elongation factor 1 epsilon-1 K15439 EEF1E1; eukaryotic translation elongation factor 1 epsilon-1
C Other AARSs
D 324940 aars1; alanine--tRNA ligase, cytoplasmic isoform 2 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 792787 aars2; alanine--tRNA ligase, mitochondrial isoform X1 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 568332 nars; asparagine--tRNA ligase, cytoplasmic K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 561673 nars2; probable asparagine--tRNA ligase, mitochondrial K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 337230 gars1; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D 449661 tars1; threonine--tRNA ligase 1, cytoplasmic isoform 2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100330276 tarsl2; threonine--tRNA ligase, cytoplasmic K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100333765 tars2; threonine--tRNA ligase, cytoplasmic-like K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 394154 sars2; serine--tRNA ligase, mitochondrial K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 445405 sars1; serine--tRNA ligase, cytoplasmic K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 368284 cars1; cysteine--tRNA ligase, cytoplasmic K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 555187 cars2; probable cysteine--tRNA ligase, mitochondrial K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 100170827 vars2; valine--tRNA ligase, mitochondrial K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 114427 vars1; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 447847 hars; histidine--tRNA ligase isoform 2 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 692329 farsa; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 793097 fars2; phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 493608 farsb; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 368235 yars1; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 556702 yars2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 393745 wars1; tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 503745 wars2; tryptophan--tRNA ligase, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 108179007 wars; tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D 445046 dtd1; D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 445510 dtd2; D-aminoacyl-tRNA deacylase 2 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 445178 aarsd1; alanyl-tRNA editing protein Aarsd1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D 791478 trnau1apb; tRNA selenocysteine 1-associated protein 1-like K25102 TRNAU1AP; tRNA selenocysteine 1-associated protein 1
D 449551 hint1; histidine triad nucleotide-binding protein 1 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 798688 hint2; histidine triad nucleotide-binding protein 2, mitochondrial K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D 796590 hint3; histidine triad nucleotide-binding protein 3 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
D 678527 si:dkey-25e12.3; adenosine 5'-monophosphoramidase HINT3 K12150 HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
D 792614 adat1; tRNA-specific adenosine deaminase 1 K15440 TAD1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]
D 100034610 adat2; tRNA-specific adenosine deaminase 2 K15441 TAD2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]
D 368634 adat3; probable inactive tRNA-specific adenosine deaminase-like protein 3 K15442 TAD3; tRNA-specific adenosine deaminase 3
C Dihydorouridine synthases
D 322715 dus1l; tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like K05542 DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]
D 100003049 dus2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like K05543 DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]
D 393647 dus3l; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like K05544 DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]
D 445096 dus4l; tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like K05545 DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]
C Methylthiotransferase
D 393600 cdkal1; threonylcarbamoyladenosine tRNA methylthiotransferase K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D 553298 trmt1; tRNA (guanine(26)-N(2))-dimethyltransferase isoform X2 K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D 334936 trmt2a; tRNA (uracil-5-)-methyltransferase homolog A K15332 TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]
D 606657 trmt2b; tRNA (uracil-5-)-methyltransferase homolog B K15331 TRMT2B; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D 566303 si:dkey-85a20.4; probable methyltransferase TARBP1 isoform X1 K15333 TRM3; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]
D 325292 nsun2; RNA cytosine C(5)-methyltransferase NSUN2 K15335 NSUN2; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]
D 553534 nsun3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial K21969 NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]
D 100149557 nsun6; putative methyltransferase NSUN6 isoform X1 K21971 NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]
D 564078 trmt5; tRNA (guanine(37)-N1)-methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D 436593 trmt61a; tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 100003205 trmt61b; tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D 563475 trmt6; tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 K03256 TRM6; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit
D 492512 ftsj1; putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase K14864 FTSJ1; tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]
D 449779 mettl1; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 100006618 mettl2a; tRNA N(3)-methylcytidine methyltransferase METTL2 K24974 METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]
D 791999 mettl6; tRNA N(3)-methylcytidine methyltransferase METTL6 K00599 METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]
D 556362 alkbh8; alkylated DNA repair protein alkB homolog 8 isoform X1 K10770 ALKBH8; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]
D 560222 trmt10a; RNA (guanine-9-)-methyltransferase domain-containing protein 2 K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 768135 trmt10b; tRNA methyltransferase 10 homolog B K15445 TRMT10; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]
D 393185 trmt11; tRNA (guanine(10)-N2)-methyltransferase homolog K15430 TRM11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]
D 541496 trmt13; tRNA:m(4)X modification enzyme TRM13 homolog K15446 TRM13; tRNA:m4X modification enzyme [EC:2.1.1.225]
D 450066 trmt44; probable tRNA (uracil-O(2)-)-methyltransferase K15447 TRM44; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]
D 570351 wdr4; tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4 K15443 TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
D 553790 trmt112; multifunctional methyltransferase subunit TRM112-like protein K15448 TRM112; multifunctional methyltransferase subunit TRM112
D 449878 trdmt1; tRNA (cytosine(38)-C(5))-methyltransferase K15336 TRDMT1; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]
D 567565 trmo; tRNA (adenine(37)-N6)-methyltransferase isoform 2 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D 562076 tyw1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D 564925 trmt12; tRNA wybutosine-synthesizing protein 2 homolog K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D 436884 tyw3; tRNA wybutosine-synthesizing protein 3 homolog K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D 100005300 lcmt2; tRNA wybutosine-synthesizing protein 4 K15451 PPM2; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]
D 557725 tyw5; tRNA wybutosine-synthesizing protein 5 K18066 TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]
D 568375 pre-miRNA 5'-monophosphate methyltransferase isoform X1 K25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]
D 108179120 bcdin3d; BCDIN3 domain containing K25191 BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 494060 pus1; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 337487 pus3; tRNA pseudouridine(38/39) synthase K01855 PUS3; tRNA pseudouridine38/39 synthase [EC:5.4.99.45]
D 556642 trub1; probable tRNA pseudouridine synthase 1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 561376 pus7l; pseudouridylate synthase PUS7L K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 402995 pus7; pseudouridylate synthase 7 homolog K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 566689 pus10; putative tRNA pseudouridine synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D 445101 rpusd4; pseudouridylate synthase RPUSD4, mitochondrial K22538 RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]
C Thiolation factors
D 553625 trmu; mitochondrial tRNA-specific 2-thiouridylase 1 K21027 TRMU; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]
D 393098 ctu1; cytoplasmic tRNA 2-thiolation protein 1 K14168 CTU1; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]
D 445166 ctu2; cytoplasmic tRNA 2-thiolation protein 2 K14169 CTU2; cytoplasmic tRNA 2-thiolation protein 2
D 562714 nfs1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D 558120 urm1; ubiquitin-related modifier 1 K12161 URM1; ubiquitin related modifier 1
D 393095 mocs3; adenylyltransferase and sulfurtransferase MOCS3 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C KEOPS/EKC complex
D 553571 tp53rk; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 368635 osgepl1; tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 550447 osgep; tRNA N6-adenosine threonylcarbamoyltransferase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 492501 tprkb; EKC/KEOPS complex subunit TPRKB K15901 TPRKB; EKC/KEOPS complex subunit TPRKB/CGI121
D 100536597 lage3; L antigen family member 3-like K15902 LAGE3; EKC/KEOPS complex subunit LAGE3/PCC1
D 568418 si:dkeyp-55f12.3; uncharacterized protein LOC568418 K15903 GON7; EKC/KEOPS complex subunit GON7
C Elongator complex
D 561039 elp1; elongator complex protein 1 K11373 ELP1; elongator complex protein 1
D 560338 elp2; elongator complex protein 2 K11374 ELP2; elongator complex protein 2
D 541509 elp3; elongator complex protein 3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D 550331 elp4; elongator complex protein 4 K11375 ELP4; elongator complex protein 4
D 790921 elp5; elongator complex protein 5 K11376 ELP5; elongator complex protein 5
D 751679 elp6; elongator complex protein 6 K11377 ELP6; elongator complex protein 6
C Elongator related proteins
D 553692 dph3; DPH3 homolog K15455 DPH3; diphthamide biosynthesis protein 3
D 751662 kti12; protein KTI12 homolog K15456 KTI12; protein KTI12
C Other tRNA modification factors
D 797343 yrdc; yrdC domain-containing protein, mitochondrial K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D 553523 trit1; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 553807 gtpbp3; tRNA modification GTPase GTPBP3, mitochondrial precursor K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 100009640 mto1; protein MTO1 homolog, mitochondrial K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 393985 qtrt1; queuine tRNA-ribosyltransferase catalytic subunit 1 K00777 QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]
D 402798 qtrt2; queuine tRNA-ribosyltransferase accessory subunit 2 K15407 QTRT2; queuine tRNA-ribosyltransferase accessory subunit
D 324947 sephs1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 352933 sephs3; selenide, water dikinase 3 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 402955 thumpd1; THUMP domain-containing protein 1 K06963 TAN1; tRNA acetyltransferase TAN1
D 492814 thg1l; probable tRNA(His) guanylyltransferase K10761 THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]
D 100037311 ate1; arginyl-tRNA--protein transferase 1 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 101886126 ate1; arginyl-tRNA--protein transferase 1 K00685 ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]
D 571036 dalrd3; DALR anticodon-binding domain-containing protein 3 K24973 DALRD3; DALR anticodon-binding domain-containing protein 3
B tRNA degradation factors
C TRAMP complex
D 557829 papd7; non-canonical poly(A) RNA polymerase PAPD7 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 568678 tent4b; terminal nucleotidyltransferase 4B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
D 317641 zcchc7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
D 406795 mtrex; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
C Rapid tRNA decay (RTD) pathway factors
D 394008 xrn1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D 321940 xrn2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D 436627 bpnt1; 3'(2'),5'-bisphosphate nucleotidase 1 K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
D 798787 rnasel3; ribonuclease-like 3 precursor K16631 ANG; angiogenin [EC:3.1.27.-]
D 100003397 rnasel2; ribonuclease like 2 precursor K16631 ANG; angiogenin [EC:3.1.27.-]
D 100001239 ifit11; interferon-induced protein with tetratricopeptide repeats 11 K24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5
D 567441 ifit10; interferon-induced protein with tetratricopeptide repeats 10 K24850 IFIT5; interferon-induced protein with tetratricopeptide repeats 5
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D 445109 elac1; zinc phosphodiesterase ELAC protein 1 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 492652 elac2; zinc phosphodiesterase ELAC protein 2 K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D 791890 rnaset2; ribonuclease T2 precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D 553485 rnaset2l; ribonuclease T2-like precursor K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
C CCA adding factors
D 415249 trnt1; CCA tRNA nucleotidyltransferase 1, mitochondrial K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D 406376 rtcb; RNA-splicing ligase RtcB homolog K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D 100126021 lars2; probable leucine--tRNA ligase, mitochondrial K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 569778 larsb; leucine--tRNA ligase, cytoplasmic K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D 325494 pars2; probable proline--tRNA ligase, mitochondrial K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D 368235 yars1; tyrosine--tRNA ligase, cytoplasmic K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 556702 yars2; tyrosine--tRNA ligase, mitochondrial K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D 393745 wars1; tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 503745 wars2; tryptophan--tRNA ligase, mitochondrial K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 108179007 wars; tryptophan--tRNA ligase, cytoplasmic K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D 449661 tars1; threonine--tRNA ligase 1, cytoplasmic isoform 2 K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100330276 tarsl2; threonine--tRNA ligase, cytoplasmic K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 100333765 tars2; threonine--tRNA ligase, cytoplasmic-like K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D 334393 iars1; isoleucine--tRNA ligase, cytoplasmic K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 100001219 iars2; isoleucine--tRNA ligase, mitochondrial K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D 280647 kars1; lysine--tRNA ligase isoform 1 K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D 324940 aars1; alanine--tRNA ligase, cytoplasmic isoform 2 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 792787 aars2; alanine--tRNA ligase, mitochondrial isoform X1 K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D 100170827 vars2; valine--tRNA ligase, mitochondrial K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 114427 vars1; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D 338183 mars1; methionine--tRNA ligase, cytoplasmic K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 566565 mars2; methionine--tRNA ligase, mitochondrial K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D 394154 sars2; serine--tRNA ligase, mitochondrial K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 445405 sars1; serine--tRNA ligase, cytoplasmic K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D 571144 dars2; aspartate--tRNA ligase, mitochondrial K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D 368284 cars1; cysteine--tRNA ligase, cytoplasmic K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 555187 cars2; probable cysteine--tRNA ligase, mitochondrial K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D 751732 ears2; nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial precursor K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D 394188 qars1; glutamine--tRNA ligase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D 337070 rars1; arginine--tRNA ligase, cytoplasmic K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 393589 rars2; probable arginine--tRNA ligase, mitochondrial K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D 692329 farsa; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 793097 fars2; phenylalanine--tRNA ligase, mitochondrial K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D 493608 farsb; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D 447847 hars; histidine--tRNA ligase isoform 2 K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D 568332 nars; asparagine--tRNA ligase, cytoplasmic K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D 561673 nars2; probable asparagine--tRNA ligase, mitochondrial K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
C Trans-editing factors
D 445046 dtd1; D-aminoacyl-tRNA deacylase 1 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 445510 dtd2; D-aminoacyl-tRNA deacylase 2 K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D 445178 aarsd1; alanyl-tRNA editing protein Aarsd1 K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D 449779 mettl1; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D 553807 gtpbp3; tRNA modification GTPase GTPBP3, mitochondrial precursor K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D 567565 trmo; tRNA (adenine(37)-N6)-methyltransferase isoform 2 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D 494060 pus1; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D 556642 trub1; probable tRNA pseudouridine synthase 1 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D 561376 pus7l; pseudouridylate synthase PUS7L K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D 402995 pus7; pseudouridylate synthase 7 homolog K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D 562714 nfs1; cysteine desulfurase, mitochondrial K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
D 553571 tp53rk; EKC/KEOPS complex subunit TP53RK K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D 368635 osgepl1; tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D 550447 osgep; tRNA N6-adenosine threonylcarbamoyltransferase K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D 100009640 mto1; protein MTO1 homolog, mitochondrial K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D 553523 trit1; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D 100073330 pts; 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D 324947 sephs1; selenide, water dikinase 1 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 352933 sephs3; selenide, water dikinase 3 K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D 797343 yrdc; yrdC domain-containing protein, mitochondrial K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
C 100750260 pnpt1; polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024