+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Drosophila virilis</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        6631663 mRNA-capping enzyme	K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74] 
E        6633735 cyclin-dependent kinase 7	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        6633704 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1	K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57] 
E        6624811 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2	K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296] 
D      Cap binding complex
E        6629188 nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        6633562 nuclear cap-binding protein subunit 1	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        6629395 nuclear cap-binding protein subunit 2B	K12883 NCBP2; nuclear cap-binding protein subunit 2 
E        6632093 nuclear cap-binding protein subunit 2-A	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
E        6623978 cleavage and polyadenylation specificity factor subunit CG7185 isoform X1	K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7 
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        6635342 protein CLP1 homolog	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        6626090 uncharacterized protein LOC6626090 isoform X1	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        6626957 cleavage and polyadenylation specificity factor subunit 1	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        6632583 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        26530659 cleavage and polyadenylation specificity factor subunit 4	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        6629999 pre-mRNA 3'-end-processing factor FIP1	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        6629596 pre-mRNA 3' end processing protein WDR33	K15542 PFS2; polyadenylation factor subunit 2 
E        6628908 WD repeat-containing protein 82	K14962 WDR82; COMPASS component SWD2 
E        6627019 serine/threonine-protein phosphatase alpha-2 isoform	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        6629847 serine/threonine-protein phosphatase alpha-2 isoform	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        6636003 serine/threonine-protein phosphatase beta isoform isoform X1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        26531416 serine/threonine-protein phosphatase alpha-3 isoform	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        6624373 serine/threonine-protein phosphatase PP1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        6625029 serine/threonine-protein phosphatase PP1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        6634780 RNA polymerase II subunit A C-terminal domain phosphatase SSU72	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        6629333 cleavage stimulation factor subunit 1	K14406 CSTF1; cleavage stimulation factor subunit 1 
E        6632584 cleavage stimulation factor subunit 2	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        6630461 symplekin	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        6628092 small nuclear ribonucleoprotein-associated protein B	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        6626906 small nuclear ribonucleoprotein Sm D3	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        26530442 probable small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        6626372 small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        6634773 probable small nuclear ribonucleoprotein G	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        6626409 uncharacterized protein LOC6626409	K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10 
E        6627262 U7 snRNA-associated Sm-like protein LSm11	K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11 
E        6632583 cleavage and polyadenylation specificity factor 73	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        6632584 cleavage stimulation factor subunit 2	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        6630461 symplekin	K06100 SYMPK; symplekin 
E        6634955 histone RNA hairpin-binding protein	K18710 SLBP; histone RNA hairpin-binding protein 
E        6626859 zinc finger CCCH domain-containing protein 13	K25593 CASP8AP2; CASP8-associated protein 2 
D      DRB sensitivity inducing factor (DSIF) complex
E        6626218 transcription elongation factor SPT4	K15171 SUPT4H1; transcription elongation factor SPT4 
E        6627102 transcription elongation factor SPT5	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        6631190 N6-adenosine-methyltransferase MT-A70-like protein isoform X2	K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] 
E        6627559 N6-adenosine-methyltransferase non-catalytic subunit	K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit 
E        6630665 uncharacterized protein LOC6630665	K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72] 
E        6626490 U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase isoform X1	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
E        6624834 pre-mRNA-splicing regulator female-lethal(2)D isoform X1	K22824 WTAP; pre-mRNA-splicing regulator WTAP 
E        6626037 protein virilizer	K22910 VIRMA; protein virilizer 
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
E        6634300 zinc finger protein swm	K13192 RBM26; RNA-binding protein 26 
E        116649722 TAR DNA-binding protein 43-like isoform X1	K23600 TARDBP; TAR DNA-binding protein 43 
E        6625013 TAR DNA-binding protein 43 isoform X2	K23600 TARDBP; TAR DNA-binding protein 43 
C    Other processing factors
D      6622343 DNA/RNA-binding protein KIN17	K13102 KIN; DNA/RNA-binding protein KIN17 
D      6623496 methyltransferase-like protein 22	K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-] 
D      26531019 G-box-binding factor	K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19] 
D      6624841 serrate RNA effector molecule homolog isoform X3	K27103 SRRT; serrate RNA effector molecule 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        6635797 RNA-binding protein 8A	K12876 RBM8A; RNA-binding protein 8A 
E        6625689 protein mago nashi	K12877 MAGOH; protein mago nashi 
E        6630701 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        6628034 ATP-dependent RNA helicase WM6	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        6629839 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        6629653 coiled-coil domain-containing protein 174	K25178 CCDC174; coiled-coil domain-containing protein 174 
E        6629869 histone deacetylase complex subunit SAP18	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        6628463 apoptotic chromatin condensation inducer in the nucleus	K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus 
E        6633000 RNA-binding protein with serine-rich domain 1	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        6624433 serine/arginine repetitive matrix protein 1	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        6629425 THO complex subunit 1	K12878 THOC1; THO complex subunit 1 
E        6635676 THO complex subunit 2	K12879 THOC2; THO complex subunit 2 
E        6635137 THO complex subunit 3	K12880 THOC3; THO complex subunit 3 
E        6630701 THO complex subunit 4	K12881 THOC4; THO complex subunit 4 
E        6625440 THO complex subunit 5	K13174 THOC5; THO complex subunit 5 
E        6623174 THO complex protein 7	K13176 THOC7; THO complex subunit 7 
D      TREX-2 complex
E        6623125 PCI domain-containing protein 2 homolog	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        6635644 probable 26S proteasome complex subunit sem1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        6633785 enhancer of yellow 2 transcription factor	K11368 ENY2; enhancer of yellow 2 transcription factor 
D      Nuclear pore complex
E        6626325 nucleoprotein TPR isoform X5	K09291 TPR; nucleoprotein TPR 
E        6626481 mRNA export factor	K14298 RAE1; mRNA export factor 
E        6629310 protein SEC13 homolog	K14004 SEC13; protein transport protein SEC13 
E        6629730 nucleoporin Nup37	K14302 NUP37; nuclear pore complex protein Nup37 
E        6625788 nuclear pore complex protein Nup75	K14304 NUP85; nuclear pore complex protein Nup85 
E        6632851 nucleoporin Nup43	K14305 NUP43; nuclear pore complex protein Nup43 
E        6626539 probable nucleoporin Nup54	K14308 NUP54; nuclear pore complex protein Nup54 
E        6636322 nuclear pore glycoprotein p62	K14306 NUP62; nuclear pore complex protein Nup62 
E        6630428 nuclear pore complex protein Nup88	K14318 NUP88; nuclear pore complex protein Nup88 
E        6631674 nuclear pore complex protein Nup93-1	K14309 NUP93; nuclear pore complex protein Nup93 
E        6630668 nuclear pore complex protein Nup93-1	K14309 NUP93; nuclear pore complex protein Nup93 
E        6630533 nuclear pore complex protein Nup98-Nup96	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        6629239 nuclear pore complex protein Nup107	K14301 NUP107; nuclear pore complex protein Nup107 
E        6632382 nuclear pore complex protein Nup133	K14300 NUP133; nuclear pore complex protein Nup133 
E        6636315 nucleoporin NUP188 homolog	K14311 NUP188; nuclear pore complex protein Nup188 
E        6627822 nuclear pore complex protein Nup154	K14312 NUP155; nuclear pore complex protein Nup155 
E        6627741 nuclear pore complex protein Nup160 homolog	K14303 NUP160; nuclear pore complex protein Nup160 
E        6632168 nucleoporin Nup35	K14313 NUP35; nuclear pore complex protein Nup53 
E        6633808 nuclear pore complex protein Nup205	K14310 NUP205; nuclear pore complex protein Nup205 
E        6635877 nuclear pore membrane glycoprotein 210 isoform X2	K14314 NUP210; nuclear pore complex protein Nup210 
E        6632997 nuclear pore complex protein Nup58	K14307 NUPL1; nucleoporin p58/p45 
E        6629937 nucleoporin Ndc1	K14315 NDC1; nucleoporin NDC1 
E        6626548 nucleoporin seh1	K14299 SEH1; nucleoporin SEH1 
E        6631828 aladin	K14320 AAAS; aladin 
E        6625652 nucleoporin Gle1	K18723 GLE1; nucleoporin GLE1 
E        6631403 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        6633679 NTF2-related export protein	K14285 NXT1_2; NTF2-related export protein 1/2 
D      Ran-mediated transport factors
E        6632744 GTP-binding nuclear protein Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        6633268 GTP-binding nuclear protein Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        6633251 ELAV-like protein 2 isoform X4	K13208 ELAVL2_3_4; ELAV like protein 2/3/4 
E        6626355 transitional endoplasmic reticulum ATPase TER94 isoform X2	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        6634149 exportin-1	K14290 XPO1; exportin-1 
E        6635294 ran-binding protein 16 isoform X1	K18460 XPO7; exportin-7 
E        6634183 ran GTPase-activating protein	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        6636939 eukaryotic translation initiation factor 4E1	K03259 EIF4E; translation initiation factor 4E 
E        6622052 eukaryotic translation initiation factor 4E1	K03259 EIF4E; translation initiation factor 4E 
E        6623437 eukaryotic translation initiation factor 4E1 isoform X2	K03259 EIF4E; translation initiation factor 4E 
E        6623452 eukaryotic translation initiation factor 4E1 isoform X1	K03259 EIF4E; translation initiation factor 4E 
E        6628915 eukaryotic initiation factor 4A isoform X1	K03257 EIF4A; translation initiation factor 4A 
E        26530460 eukaryotic translation initiation factor 4B isoform X2	K03258 EIF4B; translation initiation factor 4B 
E        6629487 eukaryotic translation initiation factor 4H	K24086 EIF4H; translation initiation factor 4H 
E        6631800 eukaryotic translation initiation factor 4H isoform X2	K24086 EIF4H; translation initiation factor 4H 
E        6628684 eukaryotic translation initiation factor 4E-binding protein 3	K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
E        6628685 eukaryotic translation initiation factor 4E-binding protein 3	K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
E        6632709 synaptic functional regulator FMR1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        6634884 cytoplasmic FMR1-interacting protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        6631175 uncharacterized protein LOC6631175	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        6633154 ATP-dependent RNA helicase bel isoform X1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        6625213 polyadenylate-binding protein	K13126 PABPC; polyadenylate-binding protein 
E        6635409 polyadenylate-binding protein-interacting protein 1 isoform X3	K14322 PAIP1; polyadenylate-binding protein-interacting protein 1 
E        6632409 polyadenylate-binding protein-interacting protein 2	K27470 PAIP2; polyadenylate-binding protein-interacting protein 2 
E        6630776 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        6623047 deformed epidermal autoregulatory factor 1 isoform X2	K23041 DEAF1; deformed epidermal autoregulatory factor 1 
E        6633362 malignant T-cell-amplified sequence 1 homolog	K07575 MCTS; malignant T-cell-amplified sequence 
E        6631982 density-regulated protein homolog	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        6630296 heterogeneous nuclear ribonucleoprotein A1 isoform X2	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        6630586 heterogeneous nuclear ribonucleoprotein 87F	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        6630224 ribonucleoprotein RB97D isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        6630585 ribonucleoprotein RB97D	K14411 MSI; RNA-binding protein Musashi 
E        6632747 chromatin modification-related protein EAF1 isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        6624106 RNA-binding protein Musashi homolog Rbp6 isoform X1	K14411 MSI; RNA-binding protein Musashi 
E        6623519 HBS1-like protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        6628803 protein pelota	K06965 PELO; protein pelota 
E        6627252 polyadenylate-binding protein 2 isoform X1	K14396 PABPN1; polyadenylate-binding protein 2 
E        6622511 DEAD-box helicase Dbp80	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        6626317 pre-mRNA-splicing factor syf1 homolog	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        6624678 regulator of chromosome condensation	K11493 RCC1; regulator of chromosome condensation 
E        6636225 transcriptional activator protein Pur-beta isoform X2	K21772 PURA; transcriptional activator protein Pur-alpha 
E        6636719 uncharacterized protein LOC6636719	K22414 POLDIP3; polymerase delta-interacting protein 3 
E        6629110 leukocyte receptor cluster member 8 homolog isoform X1	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        6622466 eukaryotic peptide chain release factor subunit 1	K03265 ETF1; peptide chain release factor subunit 1 
E        6635668 eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1	K03267 ERF3; peptide chain release factor subunit 3 
D      Protein phosphatase 2A
E        6628422 serine/threonine-protein phosphatase PP2A	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        6628906 serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit isoform X1	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        6630568 protein phosphatase PP2A 55 kDa regulatory subunit isoform X1	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        6630394 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        6632505 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        6629363 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        6632309 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        6633975 protein SMG5	K11125 SMG5; protein SMG5 
E        6631147 telomerase-binding protein EST1A	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        6629237 protein SMG8	K18734 SMG8; protein SMG8 
E        6623917 selenocysteine insertion sequence-binding protein 2	K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2 
E        6634680 probable ATP-dependent RNA helicase DHX34	K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6] 
E        6625974 GTP-binding protein 1	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        6635467 protein penguin	K14844 PUF6; pumilio homology domain family member 6 
E        6624817 unconventional myosin-Va isoform X1	K10357 MYO5; myosin V 
E        6628788 protein bicaudal D	K18739 BICD; protein bicaudal D 
E        6635990 uncharacterized protein LOC6635990	K18740 EXD1; exonuclease 3'-5' domain-containing protein 1 
D      Factors that have mRNA localization signals
E        6636049 actin-5C	K05692 ACTB_G1; actin beta/gamma 1 
E        6635861 actin-42A	K05692 ACTB_G1; actin beta/gamma 1 
E        6631169 homeotic protein bicoid	K18659 BCD; homeotic protein bicoid 
E        116650670 T-box-containing protein TBX6L	K10180 TBX6; T-box protein 6 
E        6627282 protein deadpan	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630431 enhancer of split mgamma protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630432 enhancer of split mbeta protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630438 enhancer of split m5 protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630869 enhancer of split mdelta protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630929 enhancer of split m8 protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6623507 protein hairy	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630436 enhancer of split m3 protein	K09090 HESN; hairy and enhancer of split, invertebrate 
E        6630440 enhancer of split m7 protein	K09090 HESN; hairy and enhancer of split, invertebrate 
D      Trans-acting binding proteins
E        6627075 far upstream element-binding protein 2 isoform X1	K13210 FUBP; far upstream element-binding protein 
E        6629331 elongation factor 1-alpha 2	K03231 EEF1A; elongation factor 1-alpha 
E        6634873 elongation factor 1-gamma	K03233 EEF1G; elongation factor 1-gamma 
E        6630583 RNA-binding protein squid isoform X3	K03102 SQD; squid 
E        6631175 uncharacterized protein LOC6631175	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
D      Other mRNA localization factors
E        6632709 synaptic functional regulator FMR1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        6634884 cytoplasmic FMR1-interacting protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        6623897 caprin homolog	K18743 CAPRIN1; caprin-1 
E        6628977 CUGBP Elav-like family member 2 isoform X1	K02177 BRU; bruno 
E        6635821 maternal protein exuperantia	K18745 EXU; maternal protein exuperantia 
E        6624329 Y-box factor homolog	K09276 YBX1; Y-box-binding protein 1 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        6634679 5'-3' exoribonuclease 1 isoform X1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        6624789 protein argonaute-2 isoform X1	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        6636939 eukaryotic translation initiation factor 4E1	K03259 EIF4E; translation initiation factor 4E 
E        6622052 eukaryotic translation initiation factor 4E1	K03259 EIF4E; translation initiation factor 4E 
E        6623437 eukaryotic translation initiation factor 4E1 isoform X2	K03259 EIF4E; translation initiation factor 4E 
E        6623452 eukaryotic translation initiation factor 4E1 isoform X1	K03259 EIF4E; translation initiation factor 4E 
E        6633154 ATP-dependent RNA helicase bel isoform X1	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        6627420 ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        6622638 protein LSM14 homolog B-A isoform X7	K18749 LSM14; protein LSM14 
E        6624329 Y-box factor homolog	K09276 YBX1; Y-box-binding protein 1 
E        6631544 LIM domain-containing protein jub isoform X2	K16682 AJUBA; LIM domain-containing protein 
E        26530794 putative helicase MOV-10	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        6625383 putative helicase MOV-10 isoform X1	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        6625327 putative helicase MOV-10	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        6623463 transportin-1	K18752 TNPO1; transportin-1 
E        6633975 protein SMG5	K11125 SMG5; protein SMG5 
E        6631147 telomerase-binding protein EST1A	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        6634642 protein TIS11	K15308 TTP; tristetraprolin 
E        26531534 protein lin-28 homolog	K18754 LIN28; protein lin-28 
E        6629686 uncharacterized protein LOC6629686 isoform X1	K04533 HD; huntingtin 
E        6634170 protein bicaudal C	K18756 BICC1; protein bicaudal C 
E        6630296 heterogeneous nuclear ribonucleoprotein A1 isoform X2	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        6630586 heterogeneous nuclear ribonucleoprotein 87F	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        6629485 cAMP-dependent protein kinase catalytic subunit 2 isoform X1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        6634186 cAMP-dependent protein kinase catalytic subunit 1	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        6630909 la-related protein 1 isoform X1	K18757 LARP1; la-related protein 1 
E        6629399 AF4/FMR2 family member 4	K18757 LARP1; la-related protein 1 
E        6630289 ataxin-2 homolog isoform X1	K23625 ATXN2_2L; ataxin 2/2L 
D      P-body specific factors
E        6625226 mRNA-decapping enzyme 1B	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        6626448 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        26530673 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        6627820 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        6623361 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        6635886 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        116650883 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        6627705 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        6622859 kinesin light chain isoform X2	K10407 KLC; kinesin light chain 
E        6624817 unconventional myosin-Va isoform X1	K10357 MYO5; myosin V 
E        6629611 tubulin alpha chain	K07374 TUBA; tubulin alpha 
E        6630704 tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        6635266 tubulin alpha-2 chain isoform X1	K07374 TUBA; tubulin alpha 
E        6623346 tubulin alpha-4 chain	K07374 TUBA; tubulin alpha 
E        6631175 uncharacterized protein LOC6631175	K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
E        6636213 protein Gawky isoform X1	K18412 TNRC6; trinucleotide repeat-containing gene 6 protein 
E        6636462 CCR4-NOT transcription complex subunit 1 isoform X2	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        6627427 general negative regulator of transcription subunit 2	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        6632398 regulator of gene activity isoform X2	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        6627486 LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 3	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        6624261 CCR4-NOT transcription complex subunit 7 isoform X1	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        6624990 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        6623148 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        6632733 protein PAT1 homolog 1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
E        6622180 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        6627915 enhancer of mRNA-decapping protein 4 homolog isoform X1	K12616 EDC4; enhancer of mRNA-decapping protein 4 
E        6626947 RING finger protein nhl-1 isoform X3	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        6635939 protein wech	K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27] 
E        6629797 DNA-directed RNA polymerase II subunit RPB7	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        6636748 YTH domain-containing family protein	K20102 YTHDF; YTH domain-containing family protein 
D      Stress granule specific factors
E        6631151 nucleolysin TIA-1 isoform X2	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        6631153 nucleolysin TIA-1 isoform X1	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        6635011 nucleolysin TIAR isoform X2	K13201 TIA1; nucleolysin TIA-1/TIAR 
E        6625213 polyadenylate-binding protein	K13126 PABPC; polyadenylate-binding protein 
E        6632709 synaptic functional regulator FMR1 isoform X1	K15516 FMR; fragile X mental retardation protein 
E        6630584 ras GTPase-activating protein-binding protein 2	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        6624363 eukaryotic translation initiation factor 2A	K15026 EIF2A; translation initiation factor 2A 
E        6624762 eukaryotic translation initiation factor 3 subunit B	K03253 EIF3B; translation initiation factor 3 subunit B 
E        6628915 eukaryotic initiation factor 4A isoform X1	K03257 EIF4A; translation initiation factor 4A 
E        6629839 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        26530460 eukaryotic translation initiation factor 4B isoform X2	K03258 EIF4B; translation initiation factor 4B 
E        6631945 ribosomal protein S6 kinase 2 beta	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        6628450 guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        6623792 guanine nucleotide-binding protein subunit beta-like protein	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        6631403 nuclear RNA export factor 1	K14284 NXF; nuclear RNA export factor 
E        6633570 histone deacetylase 6 isoform X1	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        6625226 mRNA-decapping enzyme 1B	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        6627420 ATP-dependent RNA helicase me31b	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        6622180 enhancer of mRNA-decapping protein 3	K12615 EDC3; enhancer of mRNA-decapping protein 3 
E        6627915 enhancer of mRNA-decapping protein 4 homolog isoform X1	K12616 EDC4; enhancer of mRNA-decapping protein 4 
E        6632733 protein PAT1 homolog 1	K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 
D      Lsm complex
E        6626448 U6 snRNA-associated Sm-like protein LSm1	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        26530673 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        6627820 U6 snRNA-associated Sm-like protein LSm4	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        6623361 U6 snRNA-associated Sm-like protein LSm5	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        6635886 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        116650883 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        6627705 U6 snRNA-associated Sm-like protein LSm7	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
D      5' exonucleases
E        6634679 5'-3' exoribonuclease 1 isoform X1	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        6629699 5'-3' exoribonuclease 2 homolog	K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        6630459 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        6624532 probable helicase with zinc finger domain	K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
C    3'-5' decay
D      Core exosome factors
E        6627753 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
E        6626078 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        6627440 exosome complex component RRP40	K03681 RRP40; exosome complex component RRP40 
E        6634363 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        6629409 exosome complex component RRP46	K12590 RRP46; exosome complex component RRP46 
E        6622965 exosome complex component MTR3	K12587 MTR3; exosome complex component MTR3 
E        6626533 exosome complex exonuclease RRP42	K12589 RRP42; exosome complex component RRP42 
E        6622359 exosome complex component rrp45	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        6630625 exosome complex exonuclease RRP44	K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] 
E        6629530 exosome component 10	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        6635635 M-phase phosphoprotein 6	K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
D      TRAMP complex
E        6633931 exosome RNA helicase MTR4	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        6630776 helicase SKI2W	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        6635793 tetratricopeptide repeat protein 37	K12600 SKI3; superkiller protein 3 
E        6632731 WD repeat-containing protein 61	K12602 WDR61; WD repeat-containing protein 61 
E        6636820 WD repeat-containing protein 61	K12602 WDR61; WD repeat-containing protein 61 
D      Ccr4-NOT complex
E        6636462 CCR4-NOT transcription complex subunit 1 isoform X2	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        6627427 general negative regulator of transcription subunit 2	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        6632398 regulator of gene activity isoform X2	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        6627486 LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 3	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        6624261 CCR4-NOT transcription complex subunit 7 isoform X1	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        6634544 CCR4-NOT transcription complex subunit 9	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        6635079 CCR4-NOT transcription complex subunit 10 isoform X2	K12607 CNOT10; CCR4-NOT transcription complex subunit 10 
D      Pan complex
E        6624990 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        6623148 PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        6630459 m7GpppX diphosphatase	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        6624532 probable helicase with zinc finger domain	K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-] 
E        6633363 uncharacterized protein LOC6633363	K26109 NRDE2; nuclear exosome regulator NRDE2 
E        6624139 protein Smaug	K27396 SMG; protein Smaug 
E        6626898 focadhesin	K27498 FOCAD; focadhesin 
C    Other degradation factors
D      RNases
E        6632646 probable ribonuclease ZC3H12B	K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-] 
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        6636328 ribonuclease 3	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
D      Helicases
D      Other RNA degradosome components
E        6627441 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        6631056 polyribonucleotide nucleotidyltransferase 1, mitochondrial	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        6626499 ATP-dependent 6-phosphofructokinase isoform X5	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        6626677 heat shock 70 kDa protein cognate 5	K04043 dnaK; molecular chaperone DnaK 
E        6627591 60 kDa heat shock protein homolog 1, mitochondrial	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        6627949 60 kDa heat shock protein homolog 2, mitochondrial	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        6634448 heat shock protein 60A	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        6626078 exosome complex component RRP4	K03679 RRP4; exosome complex component RRP4 
E        6627753 exosome complex component CSL4	K07573 CSL4; exosome complex component CSL4 
D      Cofactors
E        6634363 exosome complex component RRP41	K11600 RRP41; exosome complex component RRP41 
E        6626533 exosome complex exonuclease RRP42	K12589 RRP42; exosome complex component RRP42 
D      Others
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#Last updated: April 25, 2024