+F Repair protein KO
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DNA Repair and Recombination Proteins - Daktulosphaira vitifoliae (grape phylloxera)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 126898594 DNA oxidative demethylase ALKBH2-like K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 126901508 activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 126909491 activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 126905460 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 126905461 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 126895434 single-strand selective monofunctional uracil DNA glycosylase-like isoform X1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 126901414 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 126907170 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 126894160 DNA-(apurinic or apyrimidinic site) endonuclease K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 126895494 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 126907747 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
F 126894109 uncharacterized protein LOC126894109 K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 126902885 DNA polymerase epsilon catalytic subunit 1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 126897239 DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 126893926 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 126906271 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 126905409 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 126907295 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 126900760 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 126904672 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 126897484 DNA ligase 3 isoform X1 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 126910325 probable tyrosyl-DNA phosphodiesterase isoform X1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 126895298 aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 126896306 uncharacterized protein F21D5.5 isoform X1 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 126894551 high mobility group protein DSP1-like K10802 HMGB1; high mobility group protein B1
E 126894513 poly [ADP-ribose] polymerase K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 126899467 DNA repair protein complementing XP-C cells K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 126906201 UV excision repair protein RAD23 homolog A K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 126903840 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 126893484 cullin-4B K10609 CUL4; cullin 4
F 126905339 DNA damage-binding protein 1 isoform X1 K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 126899343 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 126899792 DNA-directed RNA polymerase II subunit RPB1-like isoform X1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 126903306 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 126894998 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 126902214 DNA-directed RNA polymerase II subunit Rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 126903044 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 126905738 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 126899025 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 126895818 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 126905148 DNA-directed RNA polymerase II subunit RPB9 isoform X1 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 126905372 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 126904901 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 126910283 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 126903840 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 126893484 cullin-4B K10609 CUL4; cullin 4
F 126905339 DNA damage-binding protein 1 isoform X1 K10610 DDB1; DNA damage-binding protein 1
F 126899775 DNA excision repair protein ERCC-8-like K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 126905095 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
F 126901606 UV-stimulated scaffold protein A-like K23720 UVSSA; UV-stimulated scaffold protein A
F 126900736 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 126899134 general transcription and DNA repair factor IIH helicase subunit XPB isoform X1 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 126902305 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 126894209 general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 126903062 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 126905560 general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 126903630 general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 126896843 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 126902911 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 126894660 cyclin-H K06634 CCNH; cyclin H
E 126904450 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 126906113 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 126897775 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 126898430 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 126901630 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 126902708 uncharacterized protein LOC126902708 K10740 RPA3; replication factor A3
E 126900287 uncharacterized protein LOC126900287 isoform X1 K10740 RPA3; replication factor A3
D Other NER factors
E 126904661 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 126896806 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 126896416 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 126900760 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 126904278 cullin-3-B-like K03869 CUL3; cullin 3
E 126897786 cullin-3 K03869 CUL3; cullin 3
E 126900179 cullin-5 K10612 CUL5; cullin 5
E 126901643 elongin-C K03872 ELOC; elongin-C
E 126900845 elongin-B K03873 ELOB; elongin-B
E 126905747 transcription elongation factor B polypeptide 3 isoform X1 K15076 ELOA; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 126895377 DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E 126895620 DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 126907899 DNA mismatch repair protein Mlh1 isoform X1 K08734 MLH1; DNA mismatch repair protein MLH1
E 126897075 mismatch repair endonuclease PMS2 isoform X1 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 126895494 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 126907747 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
E 126894109 uncharacterized protein LOC126894109 K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 126906113 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 126897775 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 126898430 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 126901630 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 126902708 uncharacterized protein LOC126902708 K10740 RPA3; replication factor A3
E 126900287 uncharacterized protein LOC126900287 isoform X1 K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 126900924 replication factor C subunit 1 isoform X1 K10754 RFC1; replication factor C subunit 1
E 126893670 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
E 126895816 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
E 126900765 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 126902239 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
E 126900430 replication factor C subunit 3 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 126905409 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 126900125 exonuclease 1 isoform X1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 126894551 high mobility group protein DSP1-like K10802 HMGB1; high mobility group protein B1
E 126900760 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 126910323 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 126907243 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 126903759 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
E 126898829 BRISC complex subunit FAM175B-like K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 126899947 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 126907581 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D BRCA1-C complex
E 126907243 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 126903759 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E 126901586 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 126901586 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 126895617 DNA repair protein RAD51 homolog 3-like isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 126902283 DNA repair protein RAD51 homolog 4-like K10871 RAD51L3; RAD51-like protein 3
E 126895920 DNA repair protein XRCC2 K10879 XRCC2; DNA-repair protein XRCC2
E 126893725 DNA repair protein XRCC3-like isoform X1 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 126904329 DNA repair and recombination protein RAD54-like isoform X1 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 126893618 DNA repair and recombination protein RAD54B-like isoform X1 K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 126906395 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 126902966 bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN-like isoform X1 K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 126906998 recQ-like DNA helicase Blm K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 126897665 recQ-like DNA helicase Blm isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 126905178 ATP-dependent DNA helicase Q4 isoform X1 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 126900518 ATP-dependent DNA helicase Q5-like K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 126906998 recQ-like DNA helicase Blm K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 126897665 recQ-like DNA helicase Blm isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 126906385 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 126907035 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 126895041 recQ-mediated genome instability protein 1-like isoform X1 K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E 126906113 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 126897775 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 126898430 replication protein A 70 kDa DNA-binding subunit-like K07466 RFA1; replication factor A1
E 126901630 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 126902708 uncharacterized protein LOC126902708 K10740 RPA3; replication factor A3
E 126900287 uncharacterized protein LOC126900287 isoform X1 K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 126902624 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 126895880 serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 126906903 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 126902108 serine/threonine-protein phosphatase 4 regulatory subunit 4-like K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
D SMC5-SMC6 complex
E 126906911 structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 126896343 structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 126901974 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 126908100 uncharacterized protein LOC126908100 K22823 NSMCE3; non-structural maintenance of chromosomes element 3
D Other HR factors
E 126907092 crossover junction endonuclease EME1-like K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 126901355 exonuclease 3'-5' domain-containing protein 2 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 126901992 crossover junction endonuclease MUS81 isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 126904274 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 126908516 structure-specific endonuclease subunit slx1 isoform X1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 126894339 flap endonuclease GEN-like K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 126895512 mortality factor 4-like protein 1 isoform X1 K11339 MORF4L1; mortality factor 4-like protein 1
E 126907712 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 126900495 fidgetin-like protein 1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 126903859 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 126900756 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 126907304 X-ray repair cross-complementing protein 5 isoform X1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
D MRX complex
E 126907243 double-strand break repair protein MRE11 isoform X1 K10865 MRE11; double-strand break repair protein MRE11
E 126903759 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 126896409 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
D Other NHEJ factors
E 126895298 aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
C FA (Fanconi anemia) pathway
D FA core complex
E 126899251 E3 ubiquitin-protein ligase FANCL-like K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E 126904185 protein deadpan-like isoform X1 K06054 HES1; hairy and enhancer of split 1
E 126906421 transcription factor HES-1-like isoform X1 K06054 HES1; hairy and enhancer of split 1
E 126894775 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 126906998 recQ-like DNA helicase Blm K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 126897665 recQ-like DNA helicase Blm isoform X1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 126906385 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 126907035 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 126895041 recQ-mediated genome instability protein 1-like isoform X1 K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E 126900800 Fanconi anemia group D2 protein isoform X1 K10891 FANCD2; fanconi anemia group D2 protein
E 126900963 Fanconi anemia group I protein-like isoform X1 K10895 FANCI; fanconi anemia group I protein
E 126897219 Fanconi anemia group I protein-like isoform X1 K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 126907581 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 126901586 DNA repair protein RAD51 homolog 1 K04482 RAD51; DNA repair protein RAD51
E 126895617 DNA repair protein RAD51 homolog 3-like isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 126906269 ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 126900811 WD repeat-containing protein 48 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 126901065 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 126904601 serine/threonine-protein phosphatase 6 regulatory subunit 3-B K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
D Ubiquitin ligases
E 126895053 E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 126908411 telomerase Cajal body protein 1 isoform X1 K23314 WRAP53; telomerase Cajal body protein 1
E 126896865 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
E 126910323 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 126905165 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 126895155 DNA repair protein Rev1 isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
D 126901915 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 126899173 ubiquitin-conjugating enzyme E2-17 kDa-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 126900734 ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 126895855 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 126905409 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 126897215 DNA-dependent metalloprotease dvc-1 K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 126905386 putative uncharacterized protein DDB_G0282133 isoform X1 K26957 GCNA; germ cell nuclear acidic protein
D 126905399 uncharacterized protein LOC126905399 K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 126900823 cell cycle checkpoint control protein RAD9A K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 126898544 checkpoint protein HUS1 isoform X1 K10903 HUS1; HUS1 checkpoint protein
D 126902292 cell cycle checkpoint protein RAD1-like isoform X1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 126900590 cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D 126893670 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 126895816 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 126900765 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 126902239 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D 126900430 replication factor C subunit 3 isoform X1 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 126902292 cell cycle checkpoint protein RAD1-like isoform X1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 126904119 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
C Triple T complex
D 126900521 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 126896717 TELO2-interacting protein 2-like K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 126902922 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 126895892 Golgi to ER traffic protein 4 homolog isoform X1 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 126896163 serine/threonine-protein kinase ATR isoform X1 K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 126895771 serine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 126904583 serine/threonine-protein kinase grp isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 126902282 serine/threonine-protein kinase Chk2-like isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 126906625 M-phase inducer phosphatase-like isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 126896198 14-3-3 protein zeta isoform X1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 126899327 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 126900427 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon
D 126901284 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 126908387 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 126897309 plastin-3 K17336 PLS3; plastin-3
D 126906084 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 126896823 vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 126901528 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 126895492 DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
C Nucleases
C Helicases
D 126895237 helicase POLQ-like isoform X1 K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D 126906973 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 126897406 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 126895249 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 126895217 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 126905334 uncharacterized protein LOC126905334 isoform X1 K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 126902262 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 126906950 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126908901 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126908941 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126909364 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126900339 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126906781 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 126906782 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 126907153 ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 126905460 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 126895434 single-strand selective monofunctional uracil DNA glycosylase-like isoform X1 K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 126905461 DNA-3-methyladenine glycosylase-like K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 126907170 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 126907340 single-stranded DNA-binding protein, mitochondrial isoform X1 K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 126907340 single-stranded DNA-binding protein, mitochondrial isoform X1 K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 126906950 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126908901 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126908941 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126909364 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 126900339 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024