+F Repair protein KO
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DNA Repair and Recombination Proteins - Klebsiella aerogenes KCTC 2190
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EAE_18130 O-6-alkylguanine-DNA:cysteine-protein methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EAE_14095 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E EAE_00985 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EAE_03195 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EAE_17920 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D EAE_11305 nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EAE_06400 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EAE_18130 O-6-alkylguanine-DNA:cysteine-protein methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EAE_24195 bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D EAE_14095 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D EAE_24190 alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E EAE_00985 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EAE_03695 G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E EAE_03195 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EAE_06020 3-methyl-adenine DNA glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E EAE_06375 formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EAE_14140 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E EAE_17920 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E EAE_21605 exonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E EAE_24010 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E EAE_08200 endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E EAE_02805 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E EAE_00345 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E EAE_06430 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E EAE_07315 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E EAE_08510 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E EAE_14465 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E EAE_23020 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E EAE_21570 nucleotide excision repair endonuclease K05984 cho; excinuclease Cho [EC:3.1.25.-]
E EAE_07910 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EAE_07315 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E EAE_00345 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E EAE_06430 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F EAE_08125 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F EAE_08130 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F EAE_04830 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F EAE_06440 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F EAE_16485 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E EAE_01780 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E EAE_09305 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E EAE_02155 DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E EAE_23340 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E EAE_00670 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E EAE_12580 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E EAE_22775 exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E EAE_11715 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E EAE_07030 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E EAE_09760 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E EAE_13885 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E EAE_16405 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E EAE_11850 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E EAE_12990 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E EAE_10540 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E EAE_22770 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E EAE_00345 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E EAE_06430 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E EAE_07910 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EAE_08515 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E EAE_05150 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E EAE_23105 very short patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E EAE_02100 recB; exonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E EAE_02110 recC; exonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E EAE_02095 recD; exonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E EAE_01520 recA; recombinase A K03553 recA; recombination protein RecA
E EAE_22855 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E EAE_22850 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E EAE_22860 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E EAE_21155 endodeoxyribonuclease RUS K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E EAE_22385 endodeoxyribonuclease RUS K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E EAE_07580 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E EAE_09445 primosomal replication protein N K02686 priB; primosomal replication protein N
E EAE_12975 primosomal replication protein N'' K04067 priC; primosomal replication protein N''
E EAE_10475 primosomal protein DnaI K02317 dnaT; DNA replication protein DnaT
E EAE_23340 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E EAE_12425 exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E EAE_12430 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E EAE_01520 recA; recombinase A K03553 recA; recombination protein RecA
E EAE_10615 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E EAE_07025 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E EAE_06455 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E EAE_02805 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E EAE_00920 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E EAE_13000 recR; recombination protein RecR K06187 recR; recombination protein RecR
E EAE_01140 recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E EAE_12415 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E EAE_22855 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E EAE_22850 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E EAE_22860 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E EAE_24115 type III restriction protein res subunit K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E EAE_12425 exonuclease subunit SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E EAE_12430 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E EAE_09785 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F EAE_24230 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F EAE_07020 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F EAE_21345 DNA topoisomerase I subunit omega K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F EAE_08210 transcriptional regulator HU subunit alpha K05787 hupA; DNA-binding protein HU-alpha
F EAE_12780 transcriptional regulator HU subunit beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F EAE_21230 putative entero exodeoxyribonuclease VIII K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F EAE_02805 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F EAE_00920 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F EAE_13000 recR; recombination protein RecR K06187 recR; recombination protein RecR
F EAE_00345 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F EAE_06430 ligB; NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F EAE_04725 fis; global DNA-binding transcriptional dual regulator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F EAE_17005 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F EAE_15160 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F EAE_23340 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F EAE_07935 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EAE_08510 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F EAE_14465 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F EAE_16885 global DNA-binding transcriptional dual regulator H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D EAE_11930 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D EAE_20980 umuC; DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D EAE_21900 umuC; DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D EAE_22145 umuC; DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D EAE_21895 DNA polymerase V subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D EAE_01520 recA; recombinase A K03553 recA; recombination protein RecA
D EAE_08430 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D EAE_01140 recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D EAE_11080 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D EAE_08515 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D EAE_16285 DNA-damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D EAE_01515 recX; recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D EAE_07755 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D EAE_15375 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D EAE_14575 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D EAE_22565 putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D EAE_11305 nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EAE_06400 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D EAE_01425 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D EAE_24240 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D EAE_01430 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D EAE_24245 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025