+C Kinase KO
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Protein Kinases - Escherichia coli BL21(DE3)
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ASerine/threonine kinases: AGC group
B PKA family
B PKG family
B PKC family [OT]
B PKN family
B AUR family [OT]
B PDK1 family
B AKT/PKB family
B SGK family [OT]
B RSK family [OT]
B NDR family
B MAST family [OT]
B YANK family
B DMPK family [OT]
B GRK family [OT]
B Other
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ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
B CAMK2 family
B CAMKL family
B DAPK family
B DCAMKL family
B MAPKAPK family [OT]
B MLCK family
B PHK family
B PIM family [OT]
B PKD family
B PSK family
B RAD53 family
B Trio family [OT]
B TSSK family
B CDPK family
B CASK family
B Trbl family
B Other
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ASerine/threonine kinases: CK1 group
B CK1 family [OT]
B TTBK family
B VRK family
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ASerine/threonine kinases: CMGC group
B CDK family
B MAPK family [OT]
B GSK family [OT]
B CLK family
B CDKL family
B DYRK family [OT]
B RCK family [OT]
B SRPK family [OT]
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ASerine/threonine kinases: STE group
B STE7 family
B STE20 family
B STE11 family
B Other
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ASerine/threonine kinases: TKL group
B IRAK family
B LISK family [OT]
B LRRK family
B MLK family
B RAF family [OT]
B RIPK family [OT]
B Other
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ASerine/threonine kinases: Other
B RGC family [OT]
B BUB family
B Bud32 family
B CAMKK family
B CDC7 family
B CK2 family
B Haspin family
B IKK family [OT]
B IRE family
B MOS family
B NAK family [OT]
B NEK family
B NKF1 family
B NKF2 family
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
B PEK family [OT]
B PLK family [OT]
B SCY1 family [OT]
B Slob family
B TBCK family
B TLK family
B TOPK family
B TTK family
B ULK family [OT]
B VPS15 family
B WEE family
B Wnk family
B ABC1 family
B Alpha family [OT]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
B PIKK family [OT]
B RIO family [OT]
B TAF1 family
B TIF1 family [OT]
B Other
B Bacterial family
C ECD_01469 hipA; inactivating GltX kinase facilitating persister formation; toxin of HipAB TA pair; autokinase K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
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AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
B TGFBR2 family [OT]
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AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
B INSR family [OT]
B PDGFR family [OT]
B FGFR family [OT]
B VEGFR family [OT]
B MET family
B TRK family [OT]
B EPH family [OT]
B AXL family
B ALK family
B TIE family
B ROR family
B DDR family
B RET family
B ROS family
B CCK family
B RYK family
B MUSK family
B LMR family [OT]
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ANon-receptor tyrosine kinases
B ABL family
B ACK family
B CSK family
B FAK family
B FES family
B JAK family [OT]
B SRC family
B TEC family
B SYK family
B Other
B Bacterial
C ECD_00984 etk; tyrosine-protein kinase, role in O-antigen capsule formation K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
C ECD_01966 wzc; colanic acid production tyrosine-protein kinase; autokinase; Ugd phosphorylase K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
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AHistidine kinases
B OmpR family
C ECD_00348 phoR; sensory histidine kinase in two-component regulatory system with PhoB K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C ECD_01127 phoQ; sensory histidine kinase in two-component regulatory system with PhoP K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C ECD_03256 envZ; sensory histidine kinase in two-component regulatory system with OmpR K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C ECD_01578 rstB; sensory histidine kinase of RstAB two-component system K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C ECD_03797 cpxA; sensory histidine kinase in two-component regulatory system with CpxR K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C ECD_04275 creC; sensory histidine kinase in two-component regulatory system with CreB or PhoB K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C ECD_01983 baeS; sensory histidine kinase in two-component regulatory system with BaeR K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C ECD_03983 basS; sensory histidine kinase in two-component regulatory system with BasR K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
C ECD_00531 cusS; copper-sensing histidine kinase in two-component regulatory system with CusR K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C ECD_02898 qseC; quorum sensing sensory histidine kinase in two-component regulatory system with QseB K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C ECD_00652 kdpD; fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C ECD_00996 torS; hybrid sensory histidine kinase in two-component regulatory system with TorR K07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
C ECD_03075 arcB; aerobic respiration control sensor histidine protein kinase, cognate to two-component response regulators ArcA and RssB K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
C ECD_01883 yedV; putative sensory kinase in two-component regulatory system with YedW K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
B NarL family
C ECD_01200 narX; sensory histidine kinase in two-component regulatory system with NarL K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C ECD_02360 narQ; sensory histidine kinase in two-component regulatory system with NarP K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
C ECD_03552 uhpB; sensory histidine kinase in two-component regulatory sytem with UhpA K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
C ECD_02145 rcsC; hybrid sensory kinase in two-component regulatory system with RcsB and YojN K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C ECD_02631 barA; hybrid sensory histidine kinase, in two-component regulatory system with UvrY K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C ECD_02280 evgS; hybrid sensory histidine kinase in two-component regulatory system with EvgA K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
B Spo family [OT]
B CitB family [OT]
C ECD_00589 citA; sensory histidine kinase in two-component regulatory system with CitB K07700 dpiB; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
B LytTR family [OT]
C ECD_02055 yehU; inner membrane putative sensory kinase in two-component system with YehT K27882 btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]
C ECD_02290 ypdA; sensor kinase regulating yhjX; pyruvate-responsive YpdAB two-component system K27884 pyrS; two-component system, LytTR family, high-concentration pyruvate sensor kinase [EC:2.7.13.3]
B NtrC family
C ECD_03754 glnL; sensory histidine kinase in two-component regulatory system with GlnG K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C ECD_03880 zraS; sensory histidine kinase in two-component regulatory system with ZraR K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C ECD_02146 atoS; sensory histidine kinase in two-component regulatory system with AtoC K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
C ECD_02448 glrK; sensor protein kinase regulating glmY sRNA in two-component system with response regulator GlrR K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
B CheA family [OT]
C ECD_01859 cheA; fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 5, 2025
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Classification taken and modified from Hanks (2003)