+C Peptidases and inhibitors KO #

  Peptidases and Inhibitors - Escherichia coli O139:H28 E24377A (ETEC)

% ! AAspartic peptidases B Family A1: pepsin family B Family A2: retropepsin family B Family A5: thermopsin family B Family A8: signal peptidase II family C EcE24377A_0027 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36] B Family A22: presenilin family B Family A24: type IV prepilin peptidase family C EcE24377A_3430 type IV prepilin peptidase family protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] C EcE24377A_3806 peptidase, A24 (type IV prepilin peptidase) family K02506 hofD; leader peptidase HopD [EC:3.4.23.43] B Family A25: gpr protease family B Family A26: omptin family B Family A28 B Family A31: HybD endopeptidase family C EcE24377A_1090 hyaD; hydrogenase 1 maturation peptidase HyaD K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-] C EcE24377A_3462 hybD; hydrogenase 2 maturation peptidase K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-] C EcE24377A_3005 hycI; hydrogenase maturation peptidase HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] B Family A36 # ACysteine peptidases B Family C1: papain family B Family C2: calpain family B Family C3: picornain family B Family C4: NIa protease family B Family C5 B Family C9 B Family C10: streptopain family B Family C11: clostripain family B Family C12: ubiquitin C-terminal hydrolase family B Family C13: legumain family B Family C14: caspase family B Family C15: pyroglutamyl peptidase I family B Family C16 B Family C19: ubiquitin-specific protease family B Family C25: gingipain family B Family C26: gamma-glutamyl hydrolase family C EcE24377A_2791 guaA; GMP synthase (glutamine-hydrolyzing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C EcE24377A_1508 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase K09473 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94] B Family C27 B Family C30 B Family C37 B Family C39 B Family C40 C EcE24377A_2473 NlpC/P60 family protein K13694 mepS; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13] C EcE24377A_1868 NlpC/P60 family protein K19303 mepH; murein DD-endopeptidase [EC:3.4.-.-] C EcE24377A_1927 lipoprotein, NlpC/P60 family K13695 nlpC; probable lipoprotein NlpC B Family C44 C EcE24377A_2606 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C EcE24377A_3700 gltB; glutamate synthase (NADPH), large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] C EcE24377A_4244 glmS; glutamine-fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C EcE24377A_0699 asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] B Family C45 B Family C46: hedgehog family B Family C47: staphopain family B Family C48: Ulp1 endopeptidase family B Family C50: separase family B Family C54: Aut2 peptidase family B Family C55: YopJ protease family B Family C56: PfpI endopeptidase family C EcE24377A_2198 hchA; chaperone protein HchA K05523 hchA; D-lactate dehydratase / protein deglycase [EC:4.2.1.130 3.5.1.124] C EcE24377A_3636 intracellular peptidase, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124] C EcE24377A_0456 thiJ; protein ThiJ K03152 thiJ; protein deglycase [EC:3.5.1.124] B Family C57: vaccinia virus I7 peptidase family B Family C58 B Family C59 B Family C60 B Family C63 B Family C64 B Family C65 B Family C67 B Family C69 B Family C70 B Family C75 B Family C76 B Family C78 B Family C79 C EcE24377A_2566 conserved hypothetical protein K18015 elaD; deubiquitinase [EC:3.4.22.-] B Family C82 C EcE24377A_2272 ErfK/YbiS/YcfS/YnhG family protein K16291 erfK; L,D-transpeptidase ErfK/SrfK C EcE24377A_1894 LysM domain/ErfK/YbiS/YcfS/YnhG family protein K19234 ynhG; L,D-transpeptidase YnhG C EcE24377A_0889 ybiS; YbiS protein K19235 ybiS; L,D-transpeptidase YbiS C EcE24377A_1235 LysM domain/ErfK/YbiS/YcfS/YnhG family protein K19236 ycfS; L,D-transpeptidase YcfS C EcE24377A_1024 putative peptidoglycan binding domain K21470 ycbB; L,D-transpeptidase YcbB B Family C83 B Family C85 B Family C86 B Family C88 B Family C89 B Family C97 B Family C98 B Family C110 # AGlutamic peptidases B Family G1 B Family G4 B Family G5: prenyl protease 2 family # AMetallo peptidases B Family M1 C EcE24377A_1033 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] B Family M2 B Family M3 C EcE24377A_3980 prlC; oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70] C EcE24377A_1747 dcp; peptidyl-dipeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5] B Family M4: thermolysin family B Family M5: mycolysin family B Family M6: immune inhibitor A family B Family M7: snapalysin family B Family M8: leishmanolysin family B Family M9 B Family M10 B Family M12: astacin/adamalysin family B Family M13: neprilysin family B Family M14: carboxypeptidase A family B Family M15: zinc D-Ala-D-Ala carboxypeptidase family C EcE24377A_1677 ddpX; D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] C EcE24377A_1278 conserved hypothetical protein K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-] B Family M16: pitrilysin family C EcE24377A_3141 ptrA; protease III K01407 ptrA; protease III [EC:3.4.24.55] C EcE24377A_1684 pqqL; peptidase, M16B family K07263 pqqL; zinc protease [EC:3.4.24.-] B Family M17: leucyl aminopeptidase family C EcE24377A_4832 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] C EcE24377A_2807 pepB; peptidase B K07751 pepB; PepB aminopeptidase [EC:3.4.11.23] B Family M18 B Family M19: membrane dipeptidase family B Family M20 C EcE24377A_2751 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C EcE24377A_1290 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] C EcE24377A_0269 pepD; aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-] C EcE24377A_1550 abgA; aminobenzoyl-glutamate utilization protein A K12940 abgA; aminobenzoyl-glutamate utilization protein A C EcE24377A_1549 abgB; aminobenzoyl-glutamate utilization protein B K12941 abgB; aminobenzoyl-glutamate utilization protein B C EcE24377A_0554 allC; allantoate amidohydrolase K02083 allC; allantoate deiminase [EC:3.5.3.9] B Family M23 C EcE24377A_2086 metalloprotease, opacity-associated protein A family K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] B Family M24 C EcE24377A_0171 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C EcE24377A_4366 pepQ; Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] C EcE24377A_3236 pepP; Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] C EcE24377A_2675 ypdF; aminopeptidase YpdF K08326 ypdF; aminopeptidase [EC:3.4.11.-] B Family M26 B Family M27 B Family M28: aminopeptidase Y family C EcE24377A_3054 iap; alkaline phosphatase isozyme conversion peptidase K09612 iap; alkaline phosphatase isozyme conversion protein [EC:3.4.11.-] B Family M29: aminopeptidase T family B Family M32: carboxypeptidase Taq family B Family M34: anthrax lethal factor family B Family M35: deuterolysin family B Family M36: fungalysin family B Family M38: beta-aspartyl dipeptidase family C EcE24377A_4927 iadA; beta-aspartyl peptidase K01305 iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-] B Family M41: FtsH endopeptidase family C EcE24377A_3663 hflB; ATP-dependent metallopeptidase HflB K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] B Family M42: glutamyl aminopeptidase family C EcE24377A_4428 aminopeptidase K18530 frvX; putative aminopeptidase FrvX [EC:3.4.11.-] B Family M43: cytophagalysin family B Family M44 B Family M48: Ste24 endopeptidase family C EcE24377A_2058 M48B family peptidase K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] C EcE24377A_1006 peptidase, M48B family K07387 K07387; metalloprotease [EC:3.4.24.-] C EcE24377A_3270 peptidase, M48B family K07387 K07387; metalloprotease [EC:3.4.24.-] C EcE24377A_2776 peptidase, M48 family K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-] B Family M49: dipeptidyl-peptidase III family B Family M50: S2P protease family C EcE24377A_0180 rseP; RIP metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] B Family M54 B Family M55: DppA aminopeptidase family B Family M56 B Family M67 B Family M72 B Family M73 B Family M74 C EcE24377A_2623 mepA; penicillin-insensitive murein endopeptidase K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-] B Family M80 B Family M82 B Family M85 B Family M88 B Family M90 C EcE24377A_2259 conserved hypothetical protein K09933 mtfA; MtfA peptidase B Family M98 # AAsparagine peptide lyases B Family N1 B Family N8 # AMixed peptidases B Family P1: DmpA aminopeptidase family B Family P2 # ASerine peptidases B Family S1: chymotrypsin family C EcE24377A_1805 peptidase, S1A (chymotrypsin) family K04775 ydgD; protease YdgD [EC:3.4.21.-] C EcE24377A_0166 degP; protease Do K04771 degP; serine protease Do [EC:3.4.21.107] C EcE24377A_3717 degQ; serine peptidase DegQ K04772 degQ; serine protease DegQ [EC:3.4.21.-] C EcE24377A_3718 degS; periplasmic serine peptidase DegS K04691 hhoB; serine protease DegS [EC:3.4.21.-] B Family S3: togavirin family B Family S6 B Family S7: flavivirin family B Family S8: subtilisin family B Family S9: prolyl oligopeptidase family C EcE24377A_2073 prtB; oligopeptidase B K01354 ptrB; oligopeptidase B [EC:3.4.21.83] B Family S10 B Family S11: D-Ala-D-Ala carboxypeptidase A family C EcE24377A_0657 dacA; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C EcE24377A_0910 dacC; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C EcE24377A_2301 dacD; serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C EcE24377A_2424 pbpG; penicillin-binding protein 7 K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-] B Family S12: D-Ala-D-Ala carboxypeptidase B family C EcE24377A_0398 ampH; penicillin-binding protein AmpH K18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase [EC:3.4.16.4 3.4.21.-] C EcE24377A_2716 beta-lactamase K21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4] B Family S13: D-Ala-D-Ala peptidase C family C EcE24377A_3667 dacB; D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] B Family S14: ClpP endopeptidase family C EcE24377A_0473 clpP; ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] B Family S15 B Family S16: lon protease family C EcE24377A_0475 lon; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] C EcE24377A_1069 peptidase, S16 (lon protease) family K04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-] B Family S21: assemblin family B Family S24: LexA family C EcE24377A_4596 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88] C EcE24377A_1328 umuD; protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-] B Family S26: signal peptidase I family C EcE24377A_2854 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] B Family S28 B Family S31 B Family S32 B Family S33 B Family S41: C-terminal processing peptidase family C EcE24377A_2059 prc; C-terminal processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] B Family S45 B Family S49: protease IV family C EcE24377A_1990 sppA; protease 4 K04773 sppA; protease IV [EC:3.4.21.-] C EcE24377A_1471 sohB; peptidase, S49 (protease IV) family K04774 sohB; serine protease SohB [EC:3.4.21.-] B Family S50 B Family S51 C EcE24377A_4565 pepE; dipeptidase E K05995 pepE; dipeptidase E [EC:3.4.13.21] B Family S53 B Family S54: Rhomboid family C EcE24377A_3900 peptidase, S54 (rhomboid) family K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105] B Family S55: SpoIVB peptidase family B Family S62 B Family S66 C EcE24377A_1337 ldcA; muramoyltetrapeptide carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] B Family S77: phage prohead processing peptidase family B Family S78 # AThreonine peptidases B Family T1: proteasome family C EcE24377A_4468 hslV; ATP-dependent protease HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] B Family T2 C EcE24377A_0899 L-asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] B Family T3: gamma-glutamyltransferase family C EcE24377A_3924 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] # APeptidases of unknown catalytic type B Family U32 C EcE24377A_2375 peptidase, U32 family K08303 prtC; U32 family peptidase [EC:3.4.-.-] C EcE24377A_1614 peptidase, U32 family K24847 rlhA; 23S rRNA 5-hydroxycytidine C2501 synthase C EcE24377A_3641 peptidase, U32 family K24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15] C EcE24377A_3640 peptidase, U32 family K24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15] B Family U62 C EcE24377A_4805 pmbA; protein PmbA K03592 pmbA; PmbA protein C EcE24377A_3727 tldD; protein TldD K03568 tldD; TldD protein # APeptidase inhibitors B Family I1: Kazal family B Family I2: Kunitz - BPTI family B Family I4: serpin family B Family I11: ecotin family C EcE24377A_2508 eco; ecotin K08276 eco; ecotin B Family I17: WAP-type family B Family I25: cystatin family B Family I27: calpastatin family B Family I32: IAP family B Family I34: IA3 family B Family I35: timp family B Family I39: alpha2M family C EcE24377A_2523 alpha-2-macroglobulin family protein K06894 yfhM; alpha-2-macroglobulin C EcE24377A_2804 alpha-2-macroglobulin domain protein K06894 yfhM; alpha-2-macroglobulin B Family I47: latexin family B Family I49: proSAAS family B Family I51: IC family B Family I57: staphostatin B family B Family I63 B Family I80 B Family I87 C EcE24377A_4733 hflC; HflC protein K04087 hflC; modulator of FtsH protease HflC C EcE24377A_4732 hflK; HflK protein K04088 hflK; modulator of FtsH protease HflK B Family I93 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 20, 2025 #
Classification taken and modified from MEROPS