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Transfer RNA Biogenesis - Escherichia coli O9 HS (commensal)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D EcHS_A2414 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D EcHS_A3233 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D EcHS_A3618 rtcB; RtcB protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D EcHS_A2537 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D EcHS_A0198 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D EcHS_A0028 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D EcHS_A0694 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D EcHS_A2249 metG; methionyl tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D EcHS_A0725 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D EcHS_A1971 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D EcHS_A3049 lysS2; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D EcHS_A4370 lysS1; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D EcHS_A1959 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D EcHS_A2833 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D EcHS_A1038 asnS; asparagine tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D EcHS_A1800 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D EcHS_A0998 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D EcHS_A0601 cysS; cysteinyl tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D EcHS_A4514 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D EcHS_A2665 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D EcHS_A1794 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D EcHS_A1793 pheT; phenylalanyl-tRNA synthetase, beta-subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D EcHS_A1713 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D EcHS_A3580 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D EcHS_A4112 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D EcHS_A1226 hinT; purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D EcHS_A3121 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D EcHS_A0199 conserved hypothetical protein TIGR00104 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D EcHS_A2469 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D EcHS_A3358 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D EcHS_A2883 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D EcHS_A2681 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D EcHS_A3476 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D EcHS_A4413 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D EcHS_A3920 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D EcHS_A3957 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D EcHS_A1848 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D EcHS_A4468 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D EcHS_A3917 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D EcHS_A4778 RNase P, class A K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D EcHS_A2414 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D EcHS_A1729 rnt; ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D EcHS_A3852 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D EcHS_A0662 rna; ribonuclease I K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D EcHS_A1399 rnb; exoribonuclease II K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D EcHS_A1892 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D EcHS_A3233 cca; multifunctional CCA protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D EcHS_A3618 rtcB; RtcB protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D EcHS_A0150 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D EcHS_A4559 kptA; RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D EcHS_A4627 ABC transporter, ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D EcHS_A0694 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D EcHS_A0198 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D EcHS_A1713 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D EcHS_A3580 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D EcHS_A1800 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D EcHS_A0028 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D EcHS_A3049 lysS2; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D EcHS_A4370 lysS1; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D EcHS_A2833 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D EcHS_A4514 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D EcHS_A2249 metG; methionyl tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D EcHS_A0998 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D EcHS_A1959 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D EcHS_A3762 glyQ; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D EcHS_A3761 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D EcHS_A0601 cysS; cysteinyl tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D EcHS_A2537 gltX; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D EcHS_A0725 glnS; glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D EcHS_A1971 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D EcHS_A1794 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D EcHS_A1793 pheT; phenylalanyl-tRNA synthetase, beta-subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D EcHS_A2665 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D EcHS_A1038 asnS; asparagine tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D EcHS_A0147 gluQ; glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D EcHS_A4112 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D EcHS_A0558 YbaK/EbsC protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D EcHS_A1873 YbaK/prolyl-tRNA synthetase-associated domain protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D EcHS_A2712 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D EcHS_A4290 dusA; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D EcHS_A3453 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D EcHS_A2274 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D EcHS_A0708 miaB; tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D EcHS_A1964 putative methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D EcHS_A1965 putative methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D EcHS_A1028 smtA; SmtA protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D EcHS_A4639 RNA methyltransferase, TrmH family, group 1 K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D EcHS_A4199 trmA; tRNA (uracil-5-)-methyltransferase K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D EcHS_A3121 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D EcHS_A2766 trmD; tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D EcHS_A3920 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D EcHS_A3862 trmH; tRNA guanosine-2'-O-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D EcHS_A2684 RNA methyltransferase, TrmH family, group 1 K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D EcHS_A3818 RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D EcHS_A0199 conserved hypothetical protein TIGR00104 K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D EcHS_A2731 putative methyltransferase K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D EcHS_A2469 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D EcHS_A3358 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D EcHS_A2935 truC; tRNA pseudouridine synthase C K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D EcHS_A2883 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D EcHS_A0062 pseudouridine synthase, RluA family K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D EcHS_A1253 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D EcHS_A1461 PP-loop family protein K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D EcHS_A3669 tusA; sulfurtransferase TusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D EcHS_A3539 dsrH; sulfur relay protein TusD/DsrH K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D EcHS_A3540 tusC; sulfur relay protein TusC/DsrF K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D EcHS_A3541 tusD; sulfurtransferase TusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D EcHS_A1077 tusE; sulfurtransferase tusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D EcHS_A2679 iscA; iron-sulfur cluster assembly protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D EcHS_A2681 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D EcHS_A3057 ygfZ; tRNA-modifying protein ygfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D EcHS_A3957 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D EcHS_A4413 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D EcHS_A2475 mnmC; tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D EcHS_A0475 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D EcHS_A0521 queC; queuosine biosynthesis protein QueC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D EcHS_A2905 queD; queuosine biosynthesis protein QueD K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D EcHS_A2918 conserved hypothetical protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D EcHS_A2938 queF; 7-cyano-7-deazaguanine reductase K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D EcHS_A4409 iron-sulfur cluster binding protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D EcHS_A1848 selD; selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D EcHS_A0577 selU; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D EcHS_A0476 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D EcHS_A0495 thiI; thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D EcHS_A0190 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D EcHS_A2605 conserved hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D EcHS_A1895 glycoprotease family protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D EcHS_A3476 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D EcHS_A3244 gcp; O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D EcHS_A4410 conserved hypothetical protein TIGR00150 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D EcHS_A2956 ThiF family protein K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C EcHS_A4422 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C EcHS_A3356 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024