+E Ubiquitin system KO
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Ubiquitin System - Echinococcus granulosus (hydatid tapeworm)
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C EGR_00261 40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C EGR_06107 Ubiquitin K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C EGR_01284 NEDD8 protein K12158 NEDD8; ubiquitin-like protein Nedd8
C EGR_06119 Small ubiquitin-related modifier 2-A K12160 SUMO; small ubiquitin-related modifier
C EGR_04935 Gamma-aminobutyric acid receptor-associated protein-like protein K08341 GABARAP; GABA(A) receptor-associated protein
C EGR_07077 Gamma-aminobutyric acid receptor-associated protein-like protein K08341 GABARAP; GABA(A) receptor-associated protein
C EGR_05279 Autophagy-related protein K08336 ATG12; ubiquitin-like protein ATG12
C EGR_02681 Ubiquitin-related modifier K12161 URM1; ubiquitin related modifier 1
C EGR_06445 Ubiquitin-fold modifier K12162 UFM1; ubiquitin-fold modifier 1
C EGR_02761 AN1-type zinc finger and ubiquitin domain-containing protein K12163 ZFAND4; AN1-type zinc finger protein 4
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AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C EGR_05361 Ubiquitin-like modifier-activating enzyme K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C EGR_01484 SUMO-activating enzyme subunit K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C EGR_06411 SUMO-activating enzyme subunit 2 K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C EGR_06855 NEDD8-activating enzyme E1 regulatory subunit K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C EGR_01038 Ubiquitin-like modifier-activating enzyme K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C EGR_01222 Ubiquitin-like modifier-activating enzyme K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C EGR_03233 Autophagy-related protein 7 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
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AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C EGR_01393 Ubiquitin-conjugating enzyme E2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C EGR_03030 Ubiquitin-conjugating enzyme E2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C EGR_09373 Ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C EGR_08951 Ubiquitin-conjugating enzyme E2 D2 K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C EGR_02968 Ubiquitin-conjugating enzyme E2 K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C EGR_06083 Ubiquitin-conjugating enzyme E2 K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C EGR_07110 Ubiquitin-conjugating enzyme E2 G2 K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C EGR_01623 Ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C EGR_07045 Ubiquitin-conjugating enzyme E2 J2 K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C EGR_00343 Ubiquitin-conjugating enzyme K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C EGR_00906 Ubiquitin-conjugating enzyme E2 L3 K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C EGR_05250 Ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C EGR_02098 Ubiquitin-conjugating enzyme E2 R1 K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C EGR_00999 Ubiquitin-conjugating enzyme E2 K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C EGR_05277 inhibitor of apoptosis (iap) domain family member K10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]
B UBL-conjugating enzymes
C EGR_02516 SUMO-conjugating enzyme UBC9 K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C EGR_00111 NEDD8-conjugating enzyme UBE2F K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C EGR_01194 Autophagy-related protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C EGR_04440 Autophagy-related protein K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C EGR_04287 Ubiquitin-fold modifier-conjugating enzyme K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C EGR_08420 Ubiquitin-protein ligase E3B K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C EGR_05702 Signal recognition particle protein K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C EGR_08548 putative E3 ubiquitin-protein ligase TRIP12 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C EGR_10270 E3 ubiquitin-protein ligase NEDD4-like protein K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C EGR_05226 E3 ubiquitin-protein ligase hyd K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C EGR_09698 G2/M phase-specific E3 ubiquitin-protein ligase K22371 G2H3; G2/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]
C EGR_02355 putative E3 ubiquitin-protein ligase HERC4 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C HECT type E3 associated proteins
B U-box type E3
C EGR_09835 Ubiquitin conjugation factor E4 A K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C EGR_04595 STIP1y and U box-containing protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C EGR_05547 Peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C EGR_04047 Pre-mRNA-processing factor K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D EGR_05763 Ribosomal protein S6 kinase beta-1 K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D EGR_02348 E3 ubiquitin-protein ligase CBL K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
C Ligand of Numb proteins
C March proteins
D EGR_05581 E3 ubiquitin-protein ligase 3-Mar K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D EGR_04457 E3 ubiquitin-protein ligase 5-Mar K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D EGR_02722 E3 ubiquitin-protein ligase 6-Mar K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D EGR_00288 Transcriptional repressor NF-X1 K12236 NFX1; transcriptional repressor NF-X1
C Pellino proteins
D EGR_02230 Protein pellino K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
C RBR proteins
D EGR_05629 E3 ubiquitin-protein ligase parkin K04556 PARK2; parkin [EC:2.3.2.31]
D EGR_03441 Protein ariadne-2 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D EGR_00450 E3 ubiquitin-protein ligase K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D EGR_05977 E3 ubiquitin-protein ligase RNF14 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
C TRAF proteins
C TRIM/RBCC proteins
D EGR_08269 Tripartite motif-containing protein 3 K11997 TRIM2_3; tripartite motif-containing protein 2/3
D EGR_02524 E3 ubiquitin-protein ligase TRIM37 K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
C UBR box proteins
D EGR_06170 E3 ubiquitin-protein ligase UBR3 K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D EGR_09233 Protein purity of essence K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D EGR_08657 Putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D EGR_02949 Autocrine motility factor receptor, isoform K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D EGR_08264 BRCA1-associated protein K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D EGR_00294 E3 ubiquitin-protein ligase CCNB1IP1 K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D EGR_02957 CCR4-NOT transcription complex subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D EGR_09346 E3 ubiquitin-protein ligase KCMF1 K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D EGR_07894 E3 ubiquitin-protein ligase LRSAM1 K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D EGR_02798 RING finger protein K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D EGR_08474 E3 ubiquitin-protein ligase mind-bomb K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D EGR_08533 E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D EGR_08536 E3 ubiquitin-protein ligase MYLIP K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D EGR_07030 E3 ubiquitin-protein ligase RING2 K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D EGR_00769 RING finger protein K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D EGR_09137 RING finger protein K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D EGR_06081 E3 ubiquitin-protein ligase K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D EGR_00731 RING finger protein K15698 RNF121_175; RING finger protein 121/175
D EGR_04472 Protein TRC8 K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D EGR_06705 RING finger protein K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D EGR_01943 RING finger protein K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D EGR_01294 U4/U6.U5 tri-snRNP-associated protein K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D EGR_05959 E3 ubiquitin-protein ligase SHPRH K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D EGR_07051 E3 ubiquitin-protein ligase synoviolin K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D EGR_03322 Transmembrane protein K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D EGR_01701 TRAF-interacting protein K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D EGR_03295 Zinc finger protein 598 K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D EGR_01583 Zinc finger SWIM domain-containing protein 2 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
B Atypical E3
C EGR_03908 Interferon regulatory factor 2-binding protein 2-A K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C EGR_00452 E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
B Multi subunit type E3
C SCF complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E EGR_02169 S-phase kinase-associated protein K03094 SKP1; S-phase kinase-associated protein 1
E EGR_02171 S-phase kinase-associated protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E EGR_09165 F-box/WD repeat-containing protein K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E EGR_03788 F-box/WD repeat-containing protein K10260 FBXW7; F-box and WD-40 domain protein 7
E EGR_04669 F-box/WD repeat-containing protein 9 K10265 FBXW9; F-box and WD-40 domain protein 9
E EGR_01685 F-box/LRR-repeat protein 2 K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E EGR_01016 F-box/LRR-repeat protein K10270 FBXL4; F-box and leucine-rich repeat protein 4
E EGR_02623 F-box only protein 32 K10305 FBXO25_32; F-box protein 25/32
E EGR_00248 F-box only protein K10306 FBXO28; F-box protein 28
E EGR_00534 F-box only protein K10312 FBXO36; F-box protein 36
E EGR_08645 F-box only protein 38 K10313 FBXO38; F-box protein 38
E EGR_03594 F-box only protein 42 K10317 FBXO42; F-box protein 42
E EGR_04791 F-box only protein 47 K10321 FBXO47; F-box protein 47
C Cul2 complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E EGR_02636 Cullin-2 K03870 CUL2; cullin 2
D Adoptor protein
E EGR_10345 Transcription elongation factor B polypeptide K03872 ELOC; elongin-C
E EGR_03761 Transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
D Target recognizing subunit
E EGR_03784 Peptidylprolyl isomerase-like protein K10348 LRR1; LRR-repeat protein 1
E EGR_08916 Peptidylprolyl isomerase-like 5 K10348 LRR1; LRR-repeat protein 1
E EGR_09655 hypothetical protein K25805 FEM1A_C; protein fem-1 homolog A/C
E EGR_08603 hypothetical protein K10350 ZYG11; Zyg-11 protein
C Cul3 complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E EGR_04583 Cullin-3 K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E EGR_04339 Kelch-like protein 3 K10443 KLHL2_3; kelch-like protein 2/3
E EGR_02296 Kelch-like protein K10448 KLHL10; kelch-like protein 10
E EGR_05746 Kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E EGR_06672 Kelch-like protein K10448 KLHL10; kelch-like protein 10
E EGR_08559 Kelch-like protein K10450 KLHL12; kelch-like protein 12
E EGR_09367 Kelch-like protein K10450 KLHL12; kelch-like protein 12
E EGR_04320 Kelch-like protein K10455 KLHL18; kelch-like protein 18
E EGR_07468 Kelch-like protein K10455 KLHL18; kelch-like protein 18
E EGR_08186 hypothetical protein K10455 KLHL18; kelch-like protein 18
E EGR_00710 Kelch-like ECH-associated protein K10456 KLHL19; kelch-like protein 19
E EGR_09927 Ectoderm-neural cortex protein K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E EGR_00259 BTB/POZ domain-containing protein K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E EGR_00263 BTB/POZ domain-containing protein K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E EGR_07241 BTB/POZ domain-containing protein 6 K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E EGR_02381 BTB/POZ domain-containing protein 9 K10481 BTBD9; BTB/POZ domain-containing protein 9
E EGR_06554 Germ cell-less protein-like protein K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E EGR_03424 BTB/POZ domain-containing protein KCTD16 K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E EGR_04966 BTB and MATH domain-containing protein 43 K10523 SPOP; speckle-type POZ protein
E EGR_08274 BTB and MATH domain-containing protein 43 K10523 SPOP; speckle-type POZ protein
C Cul4 complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E EGR_00401 Cullin-4A K10609 CUL4; cullin 4
D Adoptor protein
E EGR_05525 DNA damage-binding protein K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E EGR_03397 Protein cereblon K11793 CRBN; cereblon
E EGR_10256 hypothetical protein K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E EGR_03750 Denticleless protein K11790 DTL; denticleless
E EGR_05804 DDB1- and CUL4-associated factor K11795 DCAF6; DDB1- and CUL4-associated factor 6
E EGR_09760 DDB1- and CUL4-associated factor K11805 DCAF7; DDB1- and CUL4-associated factor 7
E EGR_04553 DDB1- and CUL4-associated factor K11801 DCAF11; DDB1- and CUL4-associated factor 11
E EGR_00672 DDB1- and CUL4-associated factor 12-like protein K11803 DCAF12; DDB1- and CUL4-associated factor 12
E EGR_00562 DDB1- and CUL4-associated factor K11806 DCAF13; DDB1- and CUL4-associated factor 13
E EGR_06846 PH-interacting protein K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E EGR_06332 WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
C Cul5 complex
D Ring finger protein
D Cullin
E EGR_02007 Cullin-5 K10612 CUL5; cullin 5
D Adoptor protein
E EGR_10345 Transcription elongation factor B polypeptide K03872 ELOC; elongin-C
E EGR_03761 Transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
D Target recognizing subunit
E EGR_02159 Suppressor of cytokine signaling 7 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E EGR_04527 Suppressor of cytokine signaling 7 K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E EGR_00493 Ankyrin repeat and SOCS box protein K10335 ASB13; ankyrin repeat and SOCS box protein 13
E EGR_08362 WD repeat and SOCS box-containing protein K10341 WSB1; WD repeat and SOCS box-containing protein 1
C Cul7 complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E EGR_02169 S-phase kinase-associated protein K03094 SKP1; S-phase kinase-associated protein 1
E EGR_02171 S-phase kinase-associated protein K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E EGR_00753 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E EGR_04378 RING-box protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
D Cullin
E EGR_06231 Vacuolar protein sorting-associated protein K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E EGR_06054 Cell division cycle protein K03363 CDC20; cell division cycle 20, cofactor of APC complex
E EGR_09407 Fizzy-related protein K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E EGR_08136 Anaphase-promoting complex subunit K03348 APC1; anaphase-promoting complex subunit 1
E EGR_06125 Cell division cycle protein K03350 APC3; anaphase-promoting complex subunit 3
E EGR_06021 Anaphase-promoting complex subunit 4 K03351 APC4; anaphase-promoting complex subunit 4
E EGR_05088 Cell division cycle protein K03353 APC6; anaphase-promoting complex subunit 6
E EGR_04212 Anaphase-promoting complex subunit K03357 APC10; anaphase-promoting complex subunit 10
C BRCC complex
D EGR_00173 putative NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D EGR_05978 BRCA1-associated RING domain protein K10683 BARD1; BRCA1-associated RING domain protein 1
D EGR_07517 DNA repair protein RAD51 K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
C CTLH complex
D EGR_00972 hypothetical protein K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D EGR_01006 Ran-binding protein K23334 RANBP9_10; Ran-binding protein 9/10
D EGR_09901 Ran-binding protein K23334 RANBP9_10; Ran-binding protein 9/10
D EGR_00694 Macrophage erythroblast attacher K18624 MAEA; macrophage erythroblast attacher
D EGR_02740 hypothetical protein K23335 GID4; glucose-induced degradation protein 4
D EGR_06473 hypothetical protein K23338 GID8; glucose-induced degradation protein 8
D EGR_02373 hypothetical protein K23339 YPEL5; protein yippee-like 5
C ERAD complex
D EGR_02949 Autocrine motility factor receptor, isoform K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D EGR_06325 Transmembrane and ubiquitin-like domain-containing protein 2 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D EGR_09495 Erlin-1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D EGR_02949 Autocrine motility factor receptor, isoform K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
C STUB1-CHIC2 complex
D EGR_04595 STIP1y and U box-containing protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
D EGR_07512 Cysteine-rich hydrophobic domain-containing protein K28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D EGR_08192 Cullin-associated NEDD8-dissociated protein K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D EGR_02950 DDRGK domain-containing protein K23344 DDRGK1; DDRGK domain-containing protein 1
D EGR_06772 Parkin coregulated gene protein K26163 PACRG; parkin coregulated gene protein
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D EGR_02941 Ubiquitin hydrolase isozyme L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D EGR_08494 Ubiquitin hydrolase isozyme L5 K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D EGR_09342 Ubiquitin hydrolase K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D EGR_09338 Ubiquitin hydrolase K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D EGR_00859 Ubiquitin hydrolase K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D EGR_06708 Ubiquitin hydrolase K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D EGR_10155 ubiquitin hydrolase K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D EGR_06950 Ubiquitin hydrolase K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D EGR_03720 Ubiquitin hydrolase K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D EGR_06954 Ubiquitin hydrolase K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D EGR_06860 Ubiquitin hydrolase K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D EGR_05858 Ubiquitin hydrolase K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D EGR_09782 Ubiquitin hydrolase K21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]
D EGR_08914 Ubiquitin hydrolase K11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12]
C OTU
D EGR_09231 Ubiquitin thioesterase K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D EGR_08701 OTU domain-containing protein 3 K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D EGR_09348 OTU domain-containing protein 6B K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D EGR_05096 Ubiquitin thioesterase zranb1-A K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
D EGR_05103 Ubiquitin thioesterase zranb1-A K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D EGR_09510 Ataxin-3 K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D EGR_03587 Josephin-2 K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D EGR_00514 hypothetical protein K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D EGR_00803 hypothetical protein K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D EGR_00173 putative NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D EGR_00174 hypothetical protein K03030 PSMD14; 26S proteasome regulatory subunit N11
D EGR_04971 26S proteasome non-ATPase regulatory subunit K03030 PSMD14; 26S proteasome regulatory subunit N11
D EGR_04511 STAM-binding protein-like protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D EGR_06775 PPPDE peptidase domain-containing protein K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
D EGR_00173 putative NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
B UBL-specific proteases (ULPs)
C EGR_06624 Sentrin-specific protease K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C EGR_05831 Sentrin-specific protease 7 K08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]
C EGR_02941 Ubiquitin hydrolase isozyme L3 K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C EGR_02214 S-formylglutathione hydrolase K22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]
C COP9 signalosome (CSN) complex
D EGR_09838 COP9 signalosome complex subunit K12175 GPS1; COP9 signalosome complex subunit 1
D EGR_04079 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D EGR_02738 COP9 signalosome complex subunit 3 K12177 COPS3; COP9 signalosome complex subunit 3
D EGR_04703 COP9 signalosome complex subunit 4 K12178 COPS4; COP9 signalosome complex subunit 4
D EGR_01372 COP9 signalosome complex subunit K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D EGR_05227 COP9 signalosome complex subunit 6 K12179 COPS6; COP9 signalosome complex subunit 6
D EGR_06047 COP9 signalosome complex subunit 7b K12180 COPS7; COP9 signalosome complex subunit 7
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 27, 2025