+F Repair protein KO
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DNA Repair and Recombination Proteins - Egretta garzetta (little egret)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 104122707 MGMT; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 104123694 ALKBH2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 K10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]
D 104134097 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D 104135401 ASCC3; activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 104123391 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 104123842 UNG; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 104132738 TDG; G/T mismatch-specific thymine DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 104135746 MPG; DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 104126284 MUTYH; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 104121779 MBD4; methyl-CpG-binding domain protein 4 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E 104130726 NEIL1; endonuclease 8-like 1 K10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]
E 104127274 NEIL2; endonuclease 8-like 2 K10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]
E 104129421 NEIL3; endonuclease 8-like 3 K10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]
E 104127739 NTHL1; endonuclease III-like protein 1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
F 104126572 POLD3; LOW QUALITY PROTEIN: DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 104129954 POLE; DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 104135016 POLE2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 104124031 POLE3; DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E 104130352 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 104124460 FEN1; flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E 104135297 POLB; DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 104131912 LIG3; LOW QUALITY PROTEIN: DNA ligase 3 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 104135668 TDP1; tyrosyl-DNA phosphodiesterase 1 K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 104123062 APTX; aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 104129250 APLF; aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 104131756 HMGB1; high mobility group protein B1 K10802 HMGB1; high mobility group protein B1
E 104125636 POLL; DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 104134588 PARP1; poly [ADP-ribose] polymerase 1 K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 104134718 PARP4; LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 4 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E 104126665 PARP3; poly [ADP-ribose] polymerase 3 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 104126701 XPC; DNA repair protein complementing XP-C cells K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 104131838 RAD23B; UV excision repair protein RAD23 homolog B K10839 RAD23; UV excision repair protein RAD23
F 104127986 centrin-2-like K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F 104124096 CUL4B; cullin-4B K10609 CUL4; cullin 4
F 104132460 CUL4A; cullin-4A K10609 CUL4; cullin 4
F 104125248 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 104134072 DDB2; DNA damage-binding protein 2 isoform X1 K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 104122670 POLR2B; DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 104130328 POLR2C; DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 104126905 POLR2D; DNA-directed RNA polymerase II subunit RPB4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 104127392 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 104134228 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 104132990 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 104122290 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 104131428 POLR2I; DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 104125876 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 104124096 CUL4B; cullin-4B K10609 CUL4; cullin 4
F 104132460 CUL4A; cullin-4A K10609 CUL4; cullin 4
F 104125248 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
F 104128370 ERCC8; DNA excision repair protein ERCC-8 isoform X1 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 104129040 ERCC6; DNA excision repair protein ERCC-6 K10841 ERCC6; DNA excision repair protein ERCC-6
F 104135963 UVSSA; UV-stimulated scaffold protein A K23720 UVSSA; UV-stimulated scaffold protein A
D TFIIH complex
E 104133726 ERCC3; TFIIH basal transcription factor complex helicase XPB subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 104123211 GTF2H1; general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 104135074 GTF2H2; general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 104130126 GTF2H3; general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 104131178 GTF2H5; general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 104124877 CDK7; cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 104128364 CCNH; cyclin-H K06634 CCNH; cyclin H
E 104131456 MNAT1; CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 104131935 RPA1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
E 104132574 RPA2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 104128674 RPA3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D Other NER factors
E 104133497 XPA; DNA repair protein complementing XP-A cells K10847 XPA; DNA-repair protein complementing XP-A cells
E 104126979 ERCC4; LOW QUALITY PROTEIN: DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 104126055 DNA repair protein complementing XP-G cells homolog K10846 ERCC5; DNA excision repair protein ERCC-5
E 104132257 MMS19; MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 104135464 CUL3; cullin-3 K03869 CUL3; cullin 3
E 104130057 CUL5; cullin-5 K10612 CUL5; cullin 5
E 104122378 TCEB1; transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 104129029 TCEB2; LOW QUALITY PROTEIN: transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
E 104134969 TCEB3; transcription elongation factor B polypeptide 3 K15076 ELOA; elongin-A
E 104126239 transcription elongation factor B polypeptide 3-like K15076 ELOA; elongin-A
E 104123073 UBAP2L; ubiquitin-associated protein 2-like K26545 UBAP2; ubiquitin-associated protein 2
E 104133868 UBAP2; ubiquitin-associated protein 2 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 104134601 MSH2; DNA mismatch repair protein Msh2 K08735 MSH2; DNA mismatch repair protein MSH2
E 104128349 MSH3; DNA mismatch repair protein Msh3 K08736 MSH3; DNA mismatch repair protein MSH3
E 104134625 MSH6; DNA mismatch repair protein Msh6 isoform X1 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 104130550 PMS1; LOW QUALITY PROTEIN: PMS1 protein homolog 1 K10864 PMS1; DNA mismatch repair protein PMS1
E 104128243 MLH1; DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 104135815 PMS2; LOW QUALITY PROTEIN: mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
E 104133225 MLH3; DNA mismatch repair protein Mlh3 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 104126572 POLD3; LOW QUALITY PROTEIN: DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 104131935 RPA1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
E 104132574 RPA2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 104128674 RPA3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 104128496 RFC1; replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 104131890 RFC2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 104123300 RFC4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E 104131360 RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 104129922 RFC5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 104130352 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 104131527 EXO1; LOW QUALITY PROTEIN: exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 104131756 HMGB1; high mobility group protein B1 K10802 HMGB1; high mobility group protein B1
E 104122479 WDR76; WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 104131715 MRE11A; double-strand break repair protein MRE11A K10865 MRE11; double-strand break repair protein MRE11
E 104133508 RAD50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 104125806 NBN; nibrin K10867 NBN; nibrin
D BRCA1-core complex
E 104134710 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 104124163 BARD1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 104134710 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 104127332 FAM175A; BRCA1-A complex subunit Abraxas K20774 FAM175A; BRCA1-A complex subunit Abraxas
E 104128863 UIMC1; BRCA1-A complex subunit RAP80 K20775 UIMC1; BRCA1-A complex subunit RAP80
E 104126856 uncharacterized protein LOC104126856 K20776 BABAM; BRISC and BRCA1-A complex member 1
E 104135631 BRE; BRCA1-A complex subunit BRE K12173 BRE; BRCA1-A complex subunit BRE
E 104124805 BRCC3; lys-63-specific deubiquitinase BRCC36 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 104134710 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 104121836 BRIP1; Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 104127534 TOPBP1; DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 104134710 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 104134129 RBBP8; DNA endonuclease RBBP8 K20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]
E 104131715 MRE11A; double-strand break repair protein MRE11A K10865 MRE11; double-strand break repair protein MRE11
E 104133508 RAD50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 104125806 NBN; nibrin K10867 NBN; nibrin
D BRCA complex
E 104134710 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 104131391 BRCA2; breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
E 104134546 PALB2; partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2
E 104130072 RAD51; DNA repair protein RAD51 homolog 1 isoform X1 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 104130072 RAD51; DNA repair protein RAD51 homolog 1 isoform X1 K04482 RAD51; DNA repair protein RAD51
E 104122071 RAD51B; DNA repair protein RAD51 homolog 2 K10869 RAD51L1; RAD51-like protein 1
E 104121842 RAD51C; DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 104131813 RAD51D; DNA repair protein RAD51 homolog 4 K10871 RAD51L3; RAD51-like protein 3
E 104131000 XRCC2; DNA repair protein XRCC2 K10879 XRCC2; DNA-repair protein XRCC2
E 104130010 XRCC3; DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E 104129745 RAD52; DNA repair protein RAD52 homolog K10873 RAD52; DNA repair and recombination protein RAD52
E 104131091 RDM1; RAD52 motif-containing protein 1 K10874 RDM1; RAD52 motif-containing protein 1
D Rad54 family proteins
E 104126278 RAD54L; DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 104126767 RAD54L2; LOW QUALITY PROTEIN: helicase ARIP4 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E 104125856 RAD54B; DNA repair and recombination protein RAD54B K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 104135128 RECQL; ATP-dependent DNA helicase Q1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 104134361 WRN; Werner syndrome ATP-dependent helicase K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 104122473 BLM; Bloom syndrome protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 104125319 RECQL5; ATP-dependent DNA helicase Q5 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 104122473 BLM; Bloom syndrome protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 104128950 TOP3B; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 104135758 TOP3A; DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 104135553 RMI1; recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E 104131935 RPA1; replication protein A 70 kDa DNA-binding subunit isoform X1 K07466 RFA1; replication factor A1
E 104132574 RPA2; replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 104128674 RPA3; replication protein A 14 kDa subunit K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 104132893 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 104132178 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 104132675 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 104135347 SMEK1; serine/threonine-protein phosphatase 4 regulatory subunit 3A K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 104128040 SMEK2; serine/threonine-protein phosphatase 4 regulatory subunit 3B K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 104127805 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 104129274 AP5M1; AP-5 complex subunit mu-1 K19023 AP5M1; AP-5 complex subunit mu-1
E 104132597 AP5Z1; AP-5 complex subunit zeta-1 K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 104123220 SMC5; structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 104128934 SMC6; structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 104127174 FAM84A; LOW QUALITY PROTEIN: protein FAM84A K22805 FAM84A; protein FAM84A
E 104131348 NSMCE1; non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 104134440 NSMCE2; E3 SUMO-protein ligase NSE2 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 104128552 melanoma-associated antigen G1-like K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 104123676 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A K22825 NSMCE4; non-structural maintenance of chromosomes element 4
E 104135911 ANKRD32; ankyrin repeat domain-containing protein 32 K26126 SLF1; SMC5-SMC6 complex localization factor protein 1
E 104125630 FAM178A; protein FAM178A K26127 SLF2; SMC5-SMC6 complex localization factor protein 2
D Other HR factors
E 104125343 EME1; crossover junction endonuclease EME1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 104127387 EME2; probable crossover junction endonuclease EME2 K10883 EME2; crossover junction endonuclease EME2
E 104122109 EXD2; exonuclease 3'-5' domain-containing protein 2 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 104122246 SWI5; DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3
E 104130438 SFR1; swi5-dependent recombination DNA repair protein 1 homolog K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E 104121975 SLX4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4 K10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
E 104128935 GEN1; flap endonuclease GEN homolog 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 104132090 SPG11; spatacsin K19026 SPG11; spatacsin
E 104122101 ZFYVE26; zinc finger FYVE domain-containing protein 26 K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 104124181 RAD51AP1; RAD51-associated protein 1 K20778 RAD51AP1; RAD51-associated protein 1
E 104132101 MORF4L1; mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 104125377 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 104126198 FIGNL1; fidgetin-like protein 1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 104126875 SPIDR; DNA repair-scaffolding protein K22806 SPIDR; DNA repair-scaffolding protein
E 104134442 FAM84B; protein FAM84B K22810 FAM84B; protein FAM84B
E 104132620 BRAT1; BRCA1-associated ATM activator 1 K23112 BRAT1; BRCA1-associated ATM activator 1
E 104131314 protein C21orf2 K23456 CFAP410; cilla- and flagella-associated protein
E 104124408 hepatoma-derived growth factor-related protein 2 K25065 HDGFL2; hepatoma-derived growth factor-related protein 2
E 104121910 ZSWIM7; LOW QUALITY PROTEIN: zinc finger SWIM domain-containing protein 7 K25770 ZSWIM7; zinc finger SWIM domain-containing protein 7
E 104124766 protein EMSY K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 104128200 HSF2BP; LOW QUALITY PROTEIN: heat shock factor 2-binding protein K25791 HSF2BP; heat shock factor 2-binding protein
E 104135393 MMS22L; LOW QUALITY PROTEIN: protein MMS22-like K26125 MMS22L; protein MMS22-like
E 104134454 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
E 104135580 PARPBP; PCNA-interacting partner K27412 PARPBP; PCNA-interacting partner
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 104134255 XRCC6; X-ray repair cross-complementing protein 6 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 104133728 XRCC5; LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 104126877 DNA-dependent protein kinase catalytic subunit-like K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
E 104127679 PRKDC; DNA-dependent protein kinase catalytic subunit K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 104131715 MRE11A; double-strand break repair protein MRE11A K10865 MRE11; double-strand break repair protein MRE11
E 104133508 RAD50; DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 104129965 LIG4; DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 104128380 XRCC4; DNA repair protein XRCC4 K10886 XRCC4; DNA-repair protein XRCC4
E 104132402 NHEJ1; non-homologous end-joining factor 1 K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
E 104125636 POLL; DNA polymerase lambda K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 104129169 DNTT; DNA nucleotidylexotransferase K00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]
E 104135297 POLB; DNA polymerase beta K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 104123062 APTX; aprataxin isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 104129250 APLF; aprataxin and PNK-like factor K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 104132392 DCLRE1C; LOW QUALITY PROTEIN: protein artemis K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 104128629 TDP2; tyrosyl-DNA phosphodiesterase 2 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 104125220 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 104128294 PWWP domain-containing protein MUM1 K23386 PWWP3; PWWP domain-containing DNA repair factor 3
E 104122005 FAM35A; LOW QUALITY PROTEIN: protein FAM35A K26129 SHLD2; shieldin complex subunit 2
C FA (Fanconi anemia) pathway
D FA core complex
E 104122433 FANCA; Fanconi anemia group A protein K10888 FANCA; fanconi anemia group A protein
E 104126469 FANCB; Fanconi anemia group B protein K10889 FANCB; fanconi anemia group B protein
E 104125908 FANCC; Fanconi anemia group C protein K10890 FANCC; fanconi anemia group C protein
E 104125758 FANCE; Fanconi anemia group E protein K10892 FANCE; fanconi anemia group E protein
E 104133884 FANCG; Fanconi anemia group G protein K10894 FANCG; fanconi anemia group G protein
E 104128692 FANCL; E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 104131708 FANCM; Fanconi anemia group M protein K10896 FANCM; fanconi anemia group M protein
E 104125593 Fanconi anemia-associated protein of 24 kDa K10898 FAAP24; fanconi anemia-associated protein
E 104124985 LOW QUALITY PROTEIN: Fanconi anemia-associated protein of 100 kDa K10993 FAAP100; fanconi anemia core complex 100 kDa subunit
D FA core complex binding factors
E 104133390 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 104127092 HES1; transcription factor HES-1 K06054 HES1; hairy and enhancer of split 1
E 104133130 centromere protein S-like K11511 APITD1; centromere protein S
E 104131224 STRA13; centromere protein X K15360 STRA13; centromere protein X
E 104122009 UBE2T; ubiquitin-conjugating enzyme E2 T K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 104122473 BLM; Bloom syndrome protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 104128950 TOP3B; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 104135758 TOP3A; DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 104135553 RMI1; recQ-mediated genome instability protein 1 K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E 104126656 FANCD2; Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein
E 104123610 FANCI; Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 104134710 BRCA1; breast cancer type 1 susceptibility protein K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]
E 104131391 BRCA2; breast cancer type 2 susceptibility protein K08775 BRCA2; breast cancer 2 susceptibility protein
E 104121836 BRIP1; Fanconi anemia group J protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 104134546 PALB2; partner and localizer of BRCA2 K10897 PALB2; partner and localizer of BRCA2
D Other FA pathway factors
E 104130875 FAN1; fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 104130072 RAD51; DNA repair protein RAD51 homolog 1 isoform X1 K04482 RAD51; DNA repair protein RAD51
E 104121842 RAD51C; DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 104135931 TELO2; telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
E 104123936 USP1; ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 104130991 WDR48; WD repeat-containing protein 48 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 104134042 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 104127897 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2 K15500 PPP6R2; serine/threonine-protein phosphatase 6 regulatory subunit 2
E 104132244 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 104126129 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 104130535 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B K15503 ANKRD44; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
E 104125061 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
D Ubiquitin ligases
E 104124849 RNF8; E3 ubiquitin-protein ligase RNF8 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 104131284 RNF168; E3 ubiquitin-protein ligase RNF168 K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
E 104133059 RNF169; E3 ubiquitin-protein ligase RNF169 K20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]
E 104132372 HERC2; E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 104124009 TPRN; taperin K24164 TPRN; taperin
E 104133857 WDR70; WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70
E 104122479 WDR76; WD repeat-containing protein 76 K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 104124104 POLH; DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 104125021 POLI; DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 104124862 POLK; DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 104126378 REV1; DNA repair protein REV1 isoform X1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 104131951 REV3L; LOW QUALITY PROTEIN: DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
D 104130199 POLN; DNA polymerase nu K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 104124067 UBE2A; ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 104133456 UBE2B; ubiquitin-conjugating enzyme E2 B K10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]
D 104121774 RAD18; E3 ubiquitin-protein ligase RAD18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 104122238 HLTF; helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 104127677 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 104132331 UBE2N; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 104130352 PCNA; proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 104135580 PARPBP; PCNA-interacting partner K27412 PARPBP; PCNA-interacting partner
D 104131055 SPRTN; sprT-like domain-containing protein Spartan K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 104124294 ACRC; acidic repeat-containing protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 104122733 RAD9B; LOW QUALITY PROTEIN: cell cycle checkpoint control protein RAD9B K10995 RAD9B; cell cycle checkpoint control protein RAD9B
D 104125963 HUS1; checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
D 104133919 RAD1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 104128345 RAD17; cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D 104131890 RFC2; replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 104123300 RFC4; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 104131360 RFC3; replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 104129922 RFC5; replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 104133919 RAD1; cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 104133532 TIPIN; TIMELESS-interacting protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 104123141 CLSPN; claspin K25773 CLSPN; claspin
C Triple T complex
D 104135931 TELO2; telomere length regulation protein TEL2 homolog K11137 TELO2; telomere length regulation protein
D 104132584 TTI1; TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
D 104127839 TTI2; TELO2-interacting protein 2 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 104128963 GET4; Golgi to ER traffic protein 4 homolog isoform X1 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 104127113 ATR; LOW QUALITY PROTEIN: serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 104124340 ATRIP; ATR-interacting protein K10905 ATRIP; ATR interacting protein
D 104130058 ATM; LOW QUALITY PROTEIN: serine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 104129228 CHEK1; serine/threonine-protein kinase Chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 104122580 CHEK2; serine/threonine-protein kinase Chk2 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 104121808 CDC25A; M-phase inducer phosphatase 1 K06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]
D 104124947 YWHAB; 14-3-3 protein beta/alpha K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 104125880 YWHAZ; 14-3-3 protein zeta/delta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 104127160 YWHAQ; 14-3-3 protein theta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 104131907 YWHAG; 14-3-3 protein gamma K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 104130133 YWHAH; 14-3-3 protein eta K16198 YWHAG_H; 14-3-3 protein gamma/eta
D 104131928 YWHAE; 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 104124714 NAV2; LOW QUALITY PROTEIN: neuron navigator 2 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 104123149 WEE1; wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 104135585 WEE2; wee1-like protein kinase 2 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 104135482 PER2; period circadian protein homolog 2 K02633 PER2; period circadian protein 2
D 104132794 PER3; period circadian protein homolog 3 K21945 PER3; period circadian protein 3
D 104135273 mediator of DNA damage checkpoint protein 1-like K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 104124260 PLS3; plastin-3 isoform X1 K17336 PLS3; plastin-3
D 104123615 apoptosis-enhancing nuclease {ECO:0000250|UniProtKB:Q8WTP8}-like K18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]
D 104126293 PLK3; serine/threonine-protein kinase PLK3 K08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]
D 104129676 NEK5; serine/threonine-protein kinase Nek5 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 104123118 NEK1; serine/threonine-protein kinase Nek1 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 104126685 NEK4; serine/threonine-protein kinase Nek4 K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D 104122951 NEK10; serine/threonine-protein kinase Nek10 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1]
D 104127502 NEK11; serine/threonine-protein kinase Nek11 K20880 NEK11; serine/threonine-protein kinase Nek11 [EC:2.7.11.1]
D 104128167 DONSON; protein downstream neighbor of Son K22422 DONSON; protein downstream neighbor of Son
D 104123880 KANK4; KN motif and ankyrin repeat domain-containing protein 4 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 104128662 KANK1; KN motif and ankyrin repeat domain-containing protein 1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 104125060 KANK3; KN motif and ankyrin repeat domain-containing protein 3 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 104122335 CHMP4C; charged multivesicular body protein 4c K24782 CHMP4C; charged multivesicular body protein 4C
D 104122830 VPS4B; vacuolar protein sorting-associated protein 4B K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 104129689 VPS4A; vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 104134120 ZFYVE19; abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 104134585 SDE2; LOW QUALITY PROTEIN: protein SDE2 homolog K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 104126568 POLQ; DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 104131779 MYBBP1A; myb-binding protein 1A K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D 104129430 PRIMPOL; DNA-directed primase/polymerase protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D 104123618 DCLRE1A; DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D 104126810 DCLRE1B; 5' exonuclease Apollo K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D 104130588 ENDOV; endonuclease V K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 104129532 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
C Helicases
D 104127344 HELQ; helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
D 104125995 ERCC6L2; DNA excision repair protein ERCC-6-like 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D 104134406 PRPF19; LOW QUALITY PROTEIN: pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 104127020 CDC5L; cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 104124156 PLRG1; pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 104132589 NUDT1; 7,8-dihydro-8-oxoguanine triphosphatase K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 104130916 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 104122179 RRM1; ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 104125884 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
D 104127145 RRM2; ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 104122707 MGMT; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 104123391 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 104123842 UNG; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 104135746 MPG; DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 104126284 MUTYH; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E 104127739 NTHL1; endonuclease III-like protein 1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 104130916 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024