+F Repair protein KO
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DNA Repair and Recombination Proteins - Anaerobutyricum hallii
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E EHLA_0281 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EHLA_0183 HhH-GPD superfamily base excision DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EHLA_2849 HhH-GPD superfamily base excision DNA repair protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E EHLA_2498 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E EHLA_1783 Superfamilies 1 and 2 helicase ATP-binding type-2 domain profile. K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D EHLA_0583 Nudix hydrolase domain profile. K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_2551 NUDIX hydrolase domain K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_2621 NUDIX hydrolase domain K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_0733 NUDIX hydrolase domain K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_1530 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D EHLA_2767 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E EHLA_0281 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EHLA_0183 HhH-GPD superfamily base excision DNA repair protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EHLA_2498 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E EHLA_0139 AP endonuclease 1 K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E EHLA_0267 deoxyribonuclease IV (phage-T4-induced) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E EHLA_1049 recJ: single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E EHLA_2439 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E EHLA_1121 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E EHLA_2622 adenosinetriphosphatase K03701 uvrA; excinuclease ABC subunit A
E EHLA_2623 UvrABC system, subunit B K03702 uvrB; excinuclease ABC subunit B
E EHLA_0319 UvrABC system, subunit C K03703 uvrC; excinuclease ABC subunit C
E EHLA_0812 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EHLA_2119 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EHLA_1121 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E EHLA_2439 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F EHLA_2916 DNA-directed RNA polymerase K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F EHLA_2915 DNA-directed RNA polymerase K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F EHLA_2782 DNA-directed RNA polymerase K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F EHLA_0619 DNA-directed RNA polymerase K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F EHLA_3143 DNA helicase K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E EHLA_2146 MutS domain V K03555 mutS; DNA mismatch repair protein MutS
E EHLA_2975 adenosinetriphosphatase K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E EHLA_2145 Ribosomal protein S5 domain 2-type fold, subgroup K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E EHLA_1240 exodeoxyribonuclease VII K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E EHLA_1241 exodeoxyribonuclease VII K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E EHLA_0313 DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E EHLA_2426 DNA-directed DNA polymerase K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E EHLA_0002 DNA-directed DNA polymerase K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E EHLA_1816 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E EHLA_0024 DNA polymerase III, delta subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E EHLA_3220 DNA-directed DNA polymerase K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E EHLA_2439 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E EHLA_0812 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EHLA_2119 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EHLA_0180 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
E EHLA_1476 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
E EHLA_2069 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
E EHLA_2601 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
E EHLA_3314 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E EHLA_2769 UvrD-like helicase C-terminal domain K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E EHLA_0948 AAA+ ATPase domain K03553 recA; recombination protein RecA
E EHLA_1777 DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E EHLA_1776 DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E EHLA_0622 Type III restriction enzyme, res subunit K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E EHLA_1023 Putative exonuclease SbcCD, C subunit K03546 sbcC; DNA repair protein SbcC/Rad50
E EHLA_1024 Type 5 capsule protein repressor C-terminal domain K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E EHLA_0948 AAA+ ATPase domain K03553 recA; recombination protein RecA
E EHLA_1662 Subunit ChlI of Mg-chelatase K04485 radA; DNA repair protein RadA/Sms
E EHLA_0004 DNA-binding, RecF, conserved site K03629 recF; DNA replication and repair protein RecF
E EHLA_1190 DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E EHLA_2533 Putative ATP-dependent DNA helicase recG C-terminal K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E EHLA_1744 ATP-dependent DNA helicase RecG, C-terminal domain K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E EHLA_1049 recJ: single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E EHLA_1299 Nucleic acid-binding, OB-fold K03584 recO; DNA repair protein RecO (recombination protein O)
E EHLA_3222 Toprim domain K06187 recR; recombination protein RecR
E EHLA_1247 P-loop containing nucleoside triphosphate hydrolase K03631 recN; DNA repair protein RecN (Recombination protein N)
E EHLA_0615 Holliday junction resolvase RecU [recU]. K03700 recU; recombination protein U
E EHLA_1777 DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E EHLA_1776 DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E EHLA_0939 DNA helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E EHLA_0938 DNA helicase K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E EHLA_1971 cas1: CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E EHLA_1636 cas1: CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E EHLA_2337 cas1: CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E EHLA_1023 Putative exonuclease SbcCD, C subunit K03546 sbcC; DNA repair protein SbcC/Rad50
E EHLA_1024 Type 5 capsule protein repressor C-terminal domain K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F EHLA_0006 DNA topoisomerase (ATP-hydrolysing) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F EHLA_0718 DNA topoisomerase (ATP-hydrolysing) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F EHLA_0005 DNA topoisomerase (ATP-hydrolysing) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F EHLA_0717 DNA topoisomerase (ATP-hydrolysing) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F EHLA_1327 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F EHLA_3065 Bacterial DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F EHLA_1049 recJ: single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F EHLA_1299 Nucleic acid-binding, OB-fold K03584 recO; DNA repair protein RecO (recombination protein O)
F EHLA_3222 Toprim domain K06187 recR; recombination protein RecR
F EHLA_2439 DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F EHLA_0197 DNA helicase/RNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EHLA_2622 adenosinetriphosphatase K03701 uvrA; excinuclease ABC subunit A
F EHLA_2623 UvrABC system, subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D EHLA_2151 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D EHLA_2547 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D EHLA_1424 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D EHLA_1512 DNA polymerase, Y-family, little finger domain K03502 umuC; DNA polymerase V
D EHLA_1579 DNA polymerase type-Y, HhH motif K03502 umuC; DNA polymerase V
C Other SOS response factors
D EHLA_0948 AAA+ ATPase domain K03553 recA; recombination protein RecA
D EHLA_1720 Repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D EHLA_1425 Peptidase S24/S26A/S26B/S26C K01356 lexA; repressor LexA [EC:3.4.21.88]
D EHLA_1247 P-loop containing nucleoside triphosphate hydrolase K03631 recN; DNA repair protein RecN (Recombination protein N)
D EHLA_0180 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
D EHLA_1476 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
D EHLA_2069 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
D EHLA_2601 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
D EHLA_3314 Nucleic acid-binding, OB-fold K03111 ssb; single-strand DNA-binding protein
D EHLA_0949 Regulatory protein RecX [recX]. K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D EHLA_0583 Nudix hydrolase domain profile. K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_2551 NUDIX hydrolase domain K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_2621 NUDIX hydrolase domain K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_0733 NUDIX hydrolase domain K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EHLA_1530 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D EHLA_2767 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D EHLA_1109 DHHA1 domain K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024