+D Receptor KO
#
G Protein-Coupled Receptors - Eurypyga helias (sunbittern)
%
!
ARhodopsin family
B Biogenic amine
C Acetylcholine (muscarinic)
D 104515306 CHRM2; muscarinic acetylcholine receptor M2 K04130 CHRM2; muscarinic acetylcholine receptor M2
D 104517052 CHRM3; muscarinic acetylcholine receptor M3 K04131 CHRM3; muscarinic acetylcholine receptor M3
D 104516753 CHRM4; muscarinic acetylcholine receptor M4 isoform X1 K04132 CHRM4; muscarinic acetylcholine receptor M4
D 104505351 CHRM5; muscarinic acetylcholine receptor M5 K04133 CHRM5; muscarinic acetylcholine receptor M5
C Adrenaline
D 104511722 ADRA1A; alpha-1A adrenergic receptor K04135 ADRA1A; adrenergic receptor alpha-1A
D 104504672 ADRA1B; alpha-1B adrenergic receptor K04136 ADRA1B; adrenergic receptor alpha-1B
D 104505305 alpha-1D adrenergic receptor-like K04137 ADRA1D; adrenergic receptor alpha-1D
D 104502699 ADRA2A; alpha-2A adrenergic receptor K04138 ADRA2A; adrenergic receptor alpha-2A
D 104505043 ADRA2C; alpha-2C adrenergic receptor K04140 ADRA2C; adrenergic receptor alpha-2C
D 104509344 ADRB2; beta-2 adrenergic receptor K04142 ADRB2; adrenergic receptor beta-2
C Dopamine
D 104505407 DRD1; D(1A) dopamine receptor K04144 DRD1; dopamine receptor D1
D 104502756 DRD2; D(2) dopamine receptor isoform X1 K04145 DRD2; dopamine receptor D2
D 104517208 DRD3; D(3) dopamine receptor K04146 DRD3; dopamine receptor D3
D 104513748 D(1) dopamine receptor-like K05840 DRD5; dopamine receptor D5
D 104503507 DRD5; D(1B) dopamine receptor K05840 DRD5; dopamine receptor D5
D 104503873 D(1C) dopamine receptor-like K05840 DRD5; dopamine receptor D5
C Dopamine and ecdysteroid
C Histamine
D 104508636 HRH1; histamine H1 receptor K04149 HRH1; histamine receptor H1
D 104505172 histamine H2 receptor-like K04150 HRH2; histamine receptor H2
D 104505130 HRH2; histamine H2 receptor K04150 HRH2; histamine receptor H2
D 104503173 histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 104510063 LOW QUALITY PROTEIN: histamine H3 receptor-like K04151 HRH3; histamine receptor H3
D 104503437 HRH3; histamine H3 receptor K04151 HRH3; histamine receptor H3
C Octopamine and tryamine
C Serotonin
D 104502436 HTR1E; 5-hydroxytryptamine receptor 1E K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104502800 HTR1D; 5-hydroxytryptamine receptor 1D K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104509638 HTR1B; 5-hydroxytryptamine receptor 1B K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104506601 HTR1F; 5-hydroxytryptamine receptor 1F K04153 HTR1; 5-hydroxytryptamine receptor 1
D 104512563 HTR2A; 5-hydroxytryptamine receptor 2A K04157 HTR2; 5-hydroxytryptamine receptor 2
D 104514218 HTR2C; 5-hydroxytryptamine receptor 2C isoform X1 K04157 HTR2; 5-hydroxytryptamine receptor 2
D 104505466 5-hydroxytryptamine receptor 2B-like K04157 HTR2; 5-hydroxytryptamine receptor 2
D 104508963 HTR4; 5-hydroxytryptamine receptor 4 K04160 HTR4; 5-hydroxytryptamine receptor 4
D 104514748 HTR5A; 5-hydroxytryptamine receptor 5A K04161 HTR5; 5-hydroxytryptamine receptor 5
D 104515415 5-hydroxytryptamine receptor 5A-like K04161 HTR5; 5-hydroxytryptamine receptor 5
D 104514714 HTR6; 5-hydroxytryptamine receptor 6 K04162 HTR6; 5-hydroxytryptamine receptor 6
D 104508137 5-hydroxytryptamine receptor 7-like K04163 HTR7; 5-hydroxytryptamine receptor 7
D 104505190 5-hydroxytryptamine receptor 7 K04163 HTR7; 5-hydroxytryptamine receptor 7
C Trace amine
D 104508550 LOW QUALITY PROTEIN: trace amine-associated receptor 5-like K05051 TAAR; trace amine associated receptor
D 104502834 trace amine-associated receptor 1-like K05051 TAAR; trace amine associated receptor
B Peptide
C Adrenomedullin (G10D)
D 104513429 GPR182; G-protein coupled receptor 182 K04242 ADMR; adrenomedullin receptor
C Adropin
D 104513153 GPR19; probable G-protein coupled receptor 19 K04316 GPR19; G protein-coupled receptor 19
C Apelin
C Anaphylatoxin
D 104512635 C3a anaphylatoxin chemotactic receptor-like K04009 C3AR1; C3a anaphylatoxin chemotactic receptor
C Angiotensin
D 104514126 AGTR1; type-1 angiotensin II receptor K04166 AGTR1; angiotensin II receptor type 1
D 104510678 AGTR2; type-2 angiotensin II receptor K04167 AGTR2; angiotensin II receptor type 2
C BigLEN
D 104511567 GPR171; LOW QUALITY PROTEIN: probable G-protein coupled receptor 171 K08441 GPR171; G protein-coupled receptor 171
C Bombesin
D 104504285 NMBR; neuromedin-B receptor K04168 NMBR; neuromedin B receptor
D 104511479 GRPR; gastrin-releasing peptide receptor K04169 GRPR; gastrin-releasing peptide receptor
D 104502493 BRS3; bombesin receptor subtype-3 K04170 BRS3; bombesin receptor subtype-3
C Bradykinin
D 104516894 BDKRB1; B1 bradykinin receptor K03915 BDKRB1; bradykinin receptor B1
D 104516893 BDKRB2; B2 bradykinin receptor K03916 BDKRB2; bradykinin receptor B2
C Cholecystokinin
C Endothelin
D 104508101 EDNRA; endothelin-1 receptor isoform X1 K04197 EDNRA; endothelin receptor type A
D 104504387 endothelin B receptor K04198 EDNRB; endothelin receptor type B
D 104506357 endothelin B receptor-like K04198 EDNRB; endothelin receptor type B
C fMet-Leu-Phe
C Follicle stimulating hormone (FSH)
D 104511054 FSHR; follicle-stimulating hormone receptor K04247 FSHR; follicle stimulating hormone receptor
C Galanin
D 104513332 GALR2; galanin receptor type 2 K04231 GALR2; galanin receptor 2
D 104505025 galanin receptor type 2-like K04231 GALR2; galanin receptor 2
D 104505206 galanin receptor type 2-like K04232 GALR3; galanin receptor 3
C Ghrelin
D 104513114 GHSR; growth hormone secretagogue receptor type 1 K04284 GHSR; growth hormone secretagogue receptor
D 104513964 LOW QUALITY PROTEIN: growth hormone secretagogue receptor type 1-like K04284 GHSR; growth hormone secretagogue receptor
C Gonadotropin-releasing hormone (GnRH)
D 104508031 GNRHR; gonadotropin-releasing hormone receptor K04280 GNRHR; gonadotropin-releasing hormone receptor
C Lutropin-choriogonadotropic hormone
D 104506844 LHCGR; lutropin-choriogonadotropic hormone receptor K04248 LHCGR; lutropin-choriogonadotropic hormone receptor
C Melanin-concentrating hormone (MCH)
D 104509997 MCHR1; melanin-concentrating hormone receptor 1 K04320 MCHR1; melanin-concentrating hormone receptor 1
D 104514023 MCHR2; LOW QUALITY PROTEIN: melanin-concentrating hormone receptor 2 K05054 MCHR2; melanin-concentrating hormone receptor 2
C Melanocortin
D 104507870 MC2R; LOW QUALITY PROTEIN: adrenocorticotropic hormone receptor K04200 MC2R; melanocortin 2 receptor
D 104512308 MC3R; melanocortin receptor 3 K04201 MC3R; melanocortin 3 receptor
D 104505081 MC4R; melanocortin receptor 4 K04202 MC4R; melanocortin 4 receptor
D 104507869 MC5R; melanocortin receptor 5 K04203 MC5R; melanocortin 5 receptor
C Motilin
D 104506494 MLNR; LOW QUALITY PROTEIN: motilin receptor K05266 MLNR; motilin receptor
C Neuromedin U
D 104512565 NMUR1; LOW QUALITY PROTEIN: neuromedin-U receptor 1 K05052 NMUR1; neuromedin U receptor 1
D 104508777 NMUR2; neuromedin-U receptor 2 K05053 NMUR2; neuromedin U receptor 2
C Neuropeptide FF
D 104503491 NPFFR1; neuropeptide FF receptor 1 K04240 NPFFR1; neuropeptide FF receptor 1
D 104502628 NPFFR2; neuropeptide FF receptor 2 K08375 NPFFR2; neuropeptide FF receptor 2
C Neuropeptide S
D 104512283 NPSR1; neuropeptide S receptor K08376 NPSR1; neuropeptide S receptor
C Neuropeptide W / neuropeptide B
D 104510612 NPBWR1; neuropeptides B/W receptor type 1 K05268 NPBWR1; neuropeptides B/W receptor 1
D 104513651 NPBWR2; neuropeptides B/W receptor type 2 K08377 NPBWR2; neuropeptides B/W receptor 2
C Neuropeptide Y
D 104502433 NPY1R; neuropeptide Y receptor type 1 K04204 NPY1R; neuropeptide Y receptor type 1
D 104506268 neuropeptide Y receptor type 2-like K04205 NPY2R; neuropeptide Y receptor type 2
D 104504240 NPY2R; neuropeptide Y receptor type 2 K04205 NPY2R; neuropeptide Y receptor type 2
D 104516414 neuropeptide Y receptor type 4-like K04206 NPY4R; neuropeptide Y receptor type 4
D 104515923 NPY5R; neuropeptide Y receptor type 5 K04207 NPY5R; neuropeptide Y receptor type 5
D 104516781 neuropeptide Y receptor type 6-like K04208 NPY6R; neuropeptide Y receptor type 6
D 104514894 GPR83; probable G-protein coupled receptor 83 K04210 GPR83; G protein-coupled receptor 83
C Neurotensin
C Opioid
D 104513194 OPRK1; kappa-type opioid receptor K04214 OPRK1; kappa-type opioid receptor
D 104504839 mu-type opioid receptor K04215 OPRM1; mu-type opioid receptor
D 104513650 OPRL1; nociceptin receptor K04216 OPRL1; nociceptin receptor
C Orexigenic neuropeptide QRFP
D 104509152 QRFPR; pyroglutamylated RFamide peptide receptor K08378 QRFPR; pyroglutamylated RFamide peptide receptor
C Orexin
D 104503901 orexin receptor type 2-like K04239 HCRTR2; hypocretin (orexin) receptor 2
C Oxytocin
D 104510759 OXTR; oxytocin receptor K04229 OXTR; oxytocin receptor
C Prokineticin
D 104516976 prokineticin receptor 2 K08380 PROKR2; prokineticin receptor 2
C Prolactin-releasing peptide (PrRP)
D 104506997 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
D 104507731 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
D 104514554 prolactin-releasing peptide receptor-like K04314 PRLHR; prolactin releasing hormone receptor
C Prosaposin
D 104505205 GPR37L1; prosaposin receptor GPR37L1 K04244 GPR37L1; prosaposin receptor
C Relaxin
D 104507775 RXFP1; relaxin receptor 1 K04306 RXFP1; relaxin family peptide receptor 1
D 104507427 LOW QUALITY PROTEIN: relaxin receptor 1-like K04307 RXFP2; relaxin family peptide receptor 2
D 104511450 RXFP3; LOW QUALITY PROTEIN: relaxin-3 receptor 1 K08397 RXFP3; relaxin family peptide receptor 3
C Somatostatin
D 104503852 SSTR1; somatostatin receptor type 1 K04217 SSTR1; somatostatin receptor 1
D 104507014 SSTR2; somatostatin receptor type 2 K04218 SSTR2; somatostatin receptor 2
D 104505421 SSTR3; somatostatin receptor type 3 K04219 SSTR3; somatostatin receptor 3
D 104505496 SSTR4; somatostatin receptor type 4 K04220 SSTR4; somatostatin receptor 4
D 104514534 SSTR5; somatostatin receptor type 5 K04221 SSTR5; somatostatin receptor 5
C Tachykinin
D 104514030 substance-P receptor-like K04222 TACR1; tachykinin receptor 1
D 104515746 TACR2; substance-K receptor K04223 TACR2; tachykinin receptor 2
D 104508172 neuromedin-K receptor-like K04224 TACR3; tachykinin receptor 3
C Thrombin
D 104514289 F2R; proteinase-activated receptor 1 K03914 F2R; coagulation factor II (thrombin) receptor
D 104506857 F2RL1; proteinase-activated receptor 2 K04234 F2RL1; coagulation factor II (thrombin) receptor-like 1
D 104515566 F2RL2; proteinase-activated receptor 3 K04235 F2RL2; coagulation factor II (thrombin) receptor-like 2
D 104515288 F2RL3; proteinase-activated receptor 4 K04236 F2RL3; coagulation factor II (thrombin) receptor-like 3
C Thyrotropin
D 104508827 TSHR; thyrotropin receptor K04249 TSHR; thyrotropin receptor
C Thyrotropin-releasing hormone (TRH)
D 104504166 thyrotropin-releasing hormone receptor-like K04282 TRHR; thyrotropin-releasing hormone receptor
D 104503107 TRHR; thyrotropin-releasing hormone receptor K04282 TRHR; thyrotropin-releasing hormone receptor
C Urotensin II
D 104512586 urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 104513270 LOW QUALITY PROTEIN: urotensin-2 receptor-like K04241 UTS2R; urotensin 2 receptor
D 104516306 UTS2R; urotensin-2 receptor K04241 UTS2R; urotensin 2 receptor
C Vasopressin
D 104514385 AVPR1B; vasopressin V1b receptor K04227 AVPR1B; arginine vasopressin receptor 1B
D 104517322 [Arg8]-vasotocin receptor-like K04228 AVPR2; arginine vasopressin receptor 2
C Neuropeptide receptors
B Chemokine
C CC Chemokine
D 104504326 CCR4; C-C chemokine receptor type 4 K04179 CCR4; C-C chemokine receptor type 4
D 104504643 C-C chemokine receptor type 5-like K04180 CCR5; C-C chemokine receptor type 5
D 104503139 C-C chemokine receptor type 5-like K04180 CCR5; C-C chemokine receptor type 5
D 104511633 CCR6; C-C chemokine receptor type 6 K04181 CCR6; C-C chemokine receptor type 6
D 104513950 LOW QUALITY PROTEIN: C-C chemokine receptor type 7-like K04182 CCR7; C-C chemokine receptor type 7
D 104512541 LOW QUALITY PROTEIN: C-C chemokine receptor type 8-like K04183 CCR8; C-C chemokine receptor type 8
D 104512971 CCR8; C-C chemokine receptor type 8 K04183 CCR8; C-C chemokine receptor type 8
D 104509187 LOW QUALITY PROTEIN: C-C chemokine receptor type 9-like K04184 CCR9; C-C chemokine receptor type 9
D 104515300 ACKR2; atypical chemokine receptor 2 K04187 ACKR2; atypical chemokine receptor 2
C CXC Chemokine
D 104512119 C-X-C chemokine receptor type 2-like K05050 CXCR2; C-X-C chemokine receptor type 2
D 104510132 CXCR4; C-X-C chemokine receptor type 4 K04189 CXCR4; C-X-C chemokine receptor type 4
D 104513828 CXCR5; C-X-C chemokine receptor type 5 K04190 CXCR5; C-X-C chemokine receptor type 5
D 104509973 CXCR6; C-X-C chemokine receptor type 6 K04191 CXCR6; C-X-C chemokine receptor type 6
D 104512663 ACKR3; atypical chemokine receptor 3 K04304 CXCR7; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
D 104505384 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 104507682 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
D 104503043 G-protein coupled receptor 35-like K04276 CXCR8; C-X-C chemokine receptor type 8
C CX3C Chemokine
D 104506862 CX3CR1; CX3C chemokine receptor 1 K04192 CX3CR1; CX3C chemokine receptor 1
C C Chemokine
D 104509574 XCR1; chemokine XC receptor 1 K04193 XCR1; XC chemokine receptor 1
C Chemokine like
D 104509761 chemokine-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 104511169 CMKLR1; chemokine-like receptor 1 K04245 CMKLR1; chemokine-like receptor 1
D 104514095 GPR1; G-protein coupled receptor 1 K04310 GPR1; G protein-coupled receptor 1
D 104506468 GPR15; G-protein coupled receptor 15 K08403 GPR15; G protein-coupled receptor 15
B Base and nucleoside
C Purine / pyrimidine
D 104505349 P2RY1; P2Y purinoceptor 1 K04270 P2RY1; P2Y purinoceptor 1
D 104510520 P2Y purinoceptor 1-like K04270 P2RY1; P2Y purinoceptor 1
D 104507609 P2Y purinoceptor 2-like K04269 P2RY2; P2Y purinoceptor 2
D 104509555 P2Y purinoceptor 4-like K04271 P2RY4; P2Y purinoceptor 4
D 104515184 P2RY6; P2Y purinoceptor 6 K04272 P2RY6; P2Y purinoceptor 6
D 104507818 P2RY8; P2Y purinoceptor 8 K08386 P2RY8; P2Y purinoceptor 8
D 104509299 P2RY12; P2Y purinoceptor 12 K04298 P2RY12; P2Y purinoceptor 12
D 104509298 P2RY13; LOW QUALITY PROTEIN: P2Y purinoceptor 13 K08388 P2RY13; P2Y purinoceptor 13
D 104511565 P2RY14; P2Y purinoceptor 14 K04299 P2RY14; P2Y purinoceptor 14
D 104515187 SUCNR1; succinate receptor 1 K10042 SUCNR1; succinate receptor 1
C Adenosine
D 104514468 ADORA1; LOW QUALITY PROTEIN: adenosine receptor A1 K04265 ADORA1; adenosine receptor A1
D 104505125 ADORA2A; adenosine receptor A2a K04266 ADORA2A; adenosine receptor A2a
D 104509249 ADORA2B; adenosine receptor A2b K04267 ADORA2B; adenosine receptor A2b
D 104504860 ADORA3; adenosine receptor A3 K04268 ADORA3; adenosine receptor A3
B Lipid
C Arachidonylglycine
D 104503045 GPR18; N-arachidonyl glycine receptor K08410 GPR18; N-arachidonyl glycine receptor
C Bile acid
C Cysteinyl leukotriene
D 104505797 CYSLTR1; cysteinyl leukotriene receptor 1 K04322 CYSLTR1; cysteinyl leukotriene receptor 1
D 104516124 CYSLTR2; cysteinyl leukotriene receptor 2 K04323 CYSLTR2; cysteinyl leukotriene receptor 2
C Free fatty acid
C HETE and oxoETE
C Leukotriene
D 104510282 leukotriene B4 receptor 1-like K04296 LTB4R1; leukotriene B4 receptor 1
C Lysophosphatidic acid
D 104514174 LPAR1; lysophosphatidic acid receptor 1 K04289 LPAR1; lysophosphatidic acid receptor 1
D 104513990 LPAR2; lysophosphatidic acid receptor 2 K04291 LPAR2; lysophosphatidic acid receptor 2
D 104512576 LPAR3; lysophosphatidic acid receptor 3 K04294 LPAR3; lysophosphatidic acid receptor 3
D 104509591 LPAR4; lysophosphatidic acid receptor 4 isoform X1 K04275 LPAR4; lysophosphatidic acid receptor 4
D 104506888 LPAR5; lysophosphatidic acid receptor 5 K08390 LPAR5; lysophosphatidic acid receptor 5
D 104512354 LPAR6; lysophosphatidic acid receptor 6 K04273 LPAR6; lysophosphatidic acid receptor 6
D 104515481 lysophosphatidic acid receptor 6-like K04273 LPAR6; lysophosphatidic acid receptor 6
D 104513039 GPR87; LOW QUALITY PROTEIN: G-protein coupled receptor 87 K08389 GPR87; G protein-coupled receptor 87
C Lysophosphatidylinositol
D 104516731 G-protein coupled receptor 55-like K08413 GPR55; G protein-coupled receptor 55
C Lysophosphatidylserine
D 104517311 GPR34; probable G-protein coupled receptor 34 K08383 GPR34; G protein-coupled receptor 34
D 104509605 putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 104509613 P2RY10; LOW QUALITY PROTEIN: putative P2Y purinoceptor 10 K04274 P2RY10; P2Y purinoceptor 10
D 104509621 GPR174; probable G-protein coupled receptor 174 K08391 GPR174; G protein-coupled receptor 174
C Oleoylethanolamide
D 104513339 GPR119; glucose-dependent insulinotropic receptor K08424 GPR119; glucose-dependent insulinotropic receptor
C Prostaglandin
D 104511465 LOW QUALITY PROTEIN: prostaglandin F2-alpha receptor-like K04262 PTGFR; prostaglandin F receptor
C Prostacyclin
C Sphingolipid
D 104514847 S1PR1; sphingosine 1-phosphate receptor 1 K04288 S1PR1; sphingosine 1-phosphate receptor 1
D 104508666 S1PR2; sphingosine 1-phosphate receptor 2 K04292 S1PR2; sphingosine 1-phosphate receptor 2
D 104511252 S1PR3; sphingosine 1-phosphate receptor 3 K04290 S1PR3; sphingosine 1-phosphate receptor 3
D 104508971 S1PR4; sphingosine 1-phosphate receptor 4 K04293 S1PR4; sphingosine 1-phosphate receptor 4
C Thromboxane
D 104512782 LOW QUALITY PROTEIN: thromboxane A2 receptor-like K04264 TBXA2R; thromboxane A2 receptor
B Vision
C Opsin
D 104509731 RHO; rhodopsin K04250 RHO; rhodopsin
D 104514959 green-sensitive opsin K04250 RHO; rhodopsin
D 104508157 OPN3; opsin-3 K04256 OPN3; c-opsin
D 104504990 pinopsin-like K04256 OPN3; c-opsin
D 104504248 opsin-VA-like K04256 OPN3; c-opsin
D 104513688 melanopsin-A-like K04255 OPN4; r-opsin
D 104514063 melanopsin-like K04255 OPN4; r-opsin
D 104507801 OPN5; opsin-5 K08385 OPN5; G0-opsin
D 104512929 opsin-5-like K08385 OPN5; G0-opsin
D 104513974 opsin-5-like K08385 OPN5; G0-opsin
D 104512902 RRH; visual pigment-like receptor peropsin K04253 RRH; visual pigment-like receptor peropsin
D 104511108 RGR; RPE-retinal G protein-coupled receptor K04254 RGR; retinal G protein coupled receptor
B Others
C Alpha-ketoglutarate
D 104509778 2-oxoglutarate receptor 1-like K08419 OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1
D 104509788 LOW QUALITY PROTEIN: 2-oxoglutarate receptor 1-like K08419 OXGR1; oxoglutarate (alpha-ketoglutarate) receptor 1
C Cannabinoid
D 104505672 CNR1; cannabinoid receptor 1 isoform X1 K04277 CNR1; cannabinoid receptor 1
D 104503168 CNR2; cannabinoid receptor 2 K04278 CNR2; cannabinoid receptor 2
C Estrogen
D 104505600 GPER1; G-protein coupled estrogen receptor 1 K04246 GPER1; G-protein coupled estrogen receptor 1
C Hydroxy-carboxylic acid
C L-Tryptophan and L-Phenylalanine
D 104508687 GPR139; probable G-protein coupled receptor 139 K08428 GPR139; G protein-coupled receptor 139
C Mas proto-oncogene and Mas-related (MRGs)
D 104505821 proto-oncogene Mas-like K04303 MAS1; proto-oncogene Mas
C Melatonin
D 104509108 MTNR1A; melatonin receptor type 1A K04285 MTNR1A; melatonin receptor type 1A
D 104505358 melatonin receptor type 1C-like K04285 MTNR1A; melatonin receptor type 1A
D 104511074 MTNR1B; melatonin receptor type 1B K04286 MTNR1B; melatonin receptor type 1B
C Oxysterol
D 104505399 GPR183; G-protein coupled receptor 183 K04305 EBI2; Epstein-Barr virus induced gene 2
D 104511524 G-protein coupled receptor 183-like K04305 EBI2; Epstein-Barr virus induced gene 2
C Platelet activating factor
D 104515827 PTAFR; platelet-activating factor receptor K04279 PTAFR; platelet-activating factor receptor
C Proton-sensing GPCRs
D 104505790 GPR65; psychosine receptor K08416 GPR65; psychosine receptor
D 104508820 GPR68; ovarian cancer G-protein coupled receptor 1 K08408 GPR68; ovarian cancer G-protein coupled receptor 1
D 104510139 GPR132; probable G-protein coupled receptor 132 K08426 GPR132; G protein-coupled receptor 132
C R-spondin
D 104509441 LGR4; leucine-rich repeat-containing G-protein coupled receptor 4 K04309 LGR4; leucine-rich repeat-containing G protein-coupled receptor 4
D 104509895 LGR5; leucine-rich repeat-containing G-protein coupled receptor 5 K04308 LGR5; leucine-rich repeat-containing G protein-coupled receptor 5
D 104516347 LGR6; leucine-rich repeat-containing G-protein coupled receptor 6 K08399 LGR6; leucine-rich repeat-containing G protein-coupled receptor 6
C Super conserved receptor expressed in brain (SREB)
D 104508714 GPR27; probable G-protein coupled receptor 27 K04301 SREB1; super conserved receptor expressed in brain 1
D 104509281 GPR85; probable G-protein coupled receptor 85 K04302 SREB2; super conserved receptor expressed in brain 2
C Trissin
C Orphan GPCRs / unclassified GPCRs
D 104514713 LOW QUALITY PROTEIN: G-protein coupled receptor 12-like K04311 GPR3; G protein-coupled receptor 3
D 104502764 G-protein coupled receptor 6-like K04313 GPR6; G protein-coupled receptor 6
D 104506949 GPR12; G-protein coupled receptor 12 K04315 GPR12; G protein-coupled receptor 12
D 104509922 GPR17; uracil nucleotide/cysteinyl leukotriene receptor K08404 GPR17; G protein-coupled receptor 17
D 104512285 GPR20; G-protein coupled receptor 20 K04317 GPR20; G protein-coupled receptor 20
D 104511895 GPR21; probable G-protein coupled receptor 21 K04318 GPR21; G protein-coupled receptor 21
D 104505532 GPR22; probable G-protein coupled receptor 22 K04319 GPR22; G protein-coupled receptor 22
D 104502931 G-protein coupled receptor 26-like K08411 GPR26; G protein-coupled receptor 26
D 104511984 GPR26; G-protein coupled receptor 26 K08411 GPR26; G protein-coupled receptor 26
D 104513564 G-protein coupled receptor 39-like K08412 GPR39; G protein-coupled receptor 39
D 104506178 GPR39; G-protein coupled receptor 39 K08412 GPR39; G protein-coupled receptor 39
D 104513831 GPR52; probable G-protein coupled receptor 52 K08407 GPR52; G protein-coupled receptor 52
D 104508947 LOW QUALITY PROTEIN: probable G-protein coupled receptor K08414 GPR61; G protein-coupled receptor 61
D 104503423 GPR63; probable G-protein coupled receptor 63 K04321 GPR63; G protein-coupled receptor 63
D 104503487 GPR82; probable G-protein coupled receptor 82 K08420 GPR82; G protein-coupled receptor 82
D 104513155 GPR141; probable G-protein coupled receptor 141 K08429 GPR141; G protein-coupled receptor 141
D 104503341 GPR146; probable G-protein coupled receptor 146 K08431 GPR146; G protein-coupled receptor 146
D 104507380 GPR148; probable G-protein coupled receptor 148 K08432 GPR148; G protein-coupled receptor 148
D 104516315 GPR149; probable G-protein coupled receptor 149 K08433 GPR149; G protein-coupled receptor 149
D 104513397 GPR160; probable G-protein coupled receptor 160 K08438 GPR160; G protein-coupled receptor 160
D 104503257 GPR161; G-protein coupled receptor 161 K08439 GPR161; G protein-coupled receptor 161
D 104516209 GPR162; LOW QUALITY PROTEIN: probable G-protein coupled receptor 162 K08440 GPR162; G protein-coupled receptor 162
D 104503358 GPR176; probable G-protein coupled receptor 176 K08442 GPR176; G protein-coupled receptor 176
#
ASecretin receptor family
B Calcium-regulating peptide
C Calcitonin
D 104510378 CALCRL; calcitonin gene-related peptide type 1 receptor K04577 CALCRL; calcitonin receptor-like
C Parathyroid hormone
B Hypothalamic hormone
C Corticotropin-releasing hormone (CRH)
D 104512215 corticotropin-releasing factor receptor 1 isoform X1 K04578 CRHR1; corticotropin releasing hormone receptor 1
C Growth hormone-releasing hormone (GHRH)
D 104516615 GHRHR; growth hormone-releasing hormone receptor K04584 GHRHR; growth hormone releasing hormone receptor
B Pancreatic peptide
C Glucagon
D 104513205 GLP1R; glucagon-like peptide 1 receptor K04581 GLP1R; glucagon-like peptide 1 receptor
D 104504151 glucagon-like peptide 2 receptor K04582 GLP2R; glucagon-like peptide 2 receptor
D 104514177 glucagon receptor-like K04583 GCGR; glucagon receptor
B Gut peptide
C Gastric inhibitory peptide (GIP)
C Vasoactive intestinal polypeptide (VIP) and pituitary adenyl cyclase-activating peptide (PACAP)
D 104502717 vasoactive intestinal polypeptide receptor-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 104516292 VIPR1; vasoactive intestinal polypeptide receptor 1 K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 104511521 LOW QUALITY PROTEIN: vasoactive intestinal polypeptide receptor 1-like K04589 VIPR1; vasoactive intestinal peptide receptor 1
D 104507189 VIPR2; vasoactive intestinal polypeptide receptor 2 K04590 VIPR2; vasoactive intestinal peptide receptor 2
D 104508748 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor K04587 ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor
C Secretin
D 104509856 SCTR; secretin receptor K04588 SCTR; secretin receptor
B Others
C Receptor activity modifying protein
D 104508805 RAMP3; receptor activity-modifying protein 3 K08449 RAMP3; receptor activity modifying protein 3
C Methuselah-like proteins (MTH)
C Pigment dispersing factor (PDF)
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AAdhesion receptor family
B Cadherin EGF LAG (CELSR)
B EGF-like module-containing mucin-like hormone receptor-like (EMR)
B Latrophilin
C 104515976 LPHN2; latrophilin-2 K04593 ADGRL2; adhesion G protein-coupled receptor L2
C 104506896 ELTD1; EGF, latrophilin and seven transmembrane domain-containing protein 1 isoform X1 K04595 ADGRL4; adhesion G protein-coupled receptor L4
B Brain-specific angiogenesis inhibitor (BAI)
B Others
C 104508553 GPR123; probable G-protein coupled receptor 123 K08460 ADGRA1; adhesion G protein-coupled receptor A1
C 104511287 probable G-protein coupled receptor 125 K08460 ADGRA1; adhesion G protein-coupled receptor A1
C 104514236 GPR125; probable G-protein coupled receptor 125 K08462 ADGRA3; adhesion G protein-coupled receptor A3
C 104508726 GPR133; probable G-protein coupled receptor 133 K08465 ADGRD1; adhesion G-protein coupled receptor D1
C 104505051 LOW QUALITY PROTEIN: probable G-protein coupled receptor 144 K08466 ADGRD2; adhesion G-protein coupled receptor D2
C 104511804 probable G-protein coupled receptor 115 K08457 ADGRF4; adhesion G-protein coupled receptor F4
C 104511705 GPR116; probable G-protein coupled receptor 116 K08458 ADGRF5; adhesion G-protein coupled receptor F5
C 104511299 GPR56; G-protein coupled receptor 56 K08450 ADGRG1; adhesion G-protein coupled receptor G1
C 104504478 G-protein coupled receptor 64-like K08451 ADGRG2; adhesion G-protein coupled receptor G2
C 104511300 GPR97; probable G-protein coupled receptor 97 K08452 ADGRG3; adhesion G-protein coupled receptor G3
C 104503918 GPR126; G-protein coupled receptor 126 K08463 ADGRG6; adhesion G-protein coupled receptor G6
C 104514229 GPR128; LOW QUALITY PROTEIN: probable G-protein coupled receptor 128 K08464 ADGRG7; adhesion G-protein coupled receptor G7
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AMetabotropic glutamate receptor family
B Glutamate (metabotropic)
C 104503170 GRM1; metabotropic glutamate receptor 1 K04603 GRM1; metabotropic glutamate receptor 1
C 104516443 GRM2; metabotropic glutamate receptor 2 K04605 GRM2; metabotropic glutamate receptor 2
C 104510061 GRM3; metabotropic glutamate receptor 3 isoform X1 K04606 GRM3; metabotropic glutamate receptor 3
C 104514000 metabotropic glutamate receptor 4 K04607 GRM4; metabotropic glutamate receptor 4
C 104517301 GRM7; metabotropic glutamate receptor 7 K04609 GRM7; metabotropic glutamate receptor 7
B GABA
B Calcium-sensing
C 104507865 GPRC6A; G-protein coupled receptor family C group 6 member A K04622 GPRC6A; G protein-coupled receptor family C group 6 member A
B Orphan GPRC5
C 104506146 GPRC5A; retinoic acid-induced protein 3 K08468 GPRC5A; G protein-coupled receptor family C group 5 member A
C 104514453 GPRC5B; G-protein coupled receptor family C group 5 member B K04619 GPRC5B; G protein-coupled receptor family C group 5 member B
B Unclassified GPCRs
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AFrizzled / Smoothened family
B 104505137 frizzled-7 K02432 FZD1_7; frizzled 1/7
B 104508641 frizzled-2 K02235 FZD2; frizzled 2
B 104506981 FZD3; frizzled-3 K02329 FZD3; frizzled 3
B 104513093 FZD4; frizzled-4 K02354 FZD4; frizzled 4
B 104512719 frizzled-5-like K02375 FZD5_8; frizzled 5/8
B 104504195 FZD6; frizzled-6 K02376 FZD6; frizzled 6
B 104504306 FZD10; frizzled-10 K02842 FZD9_10; frizzled 9/10
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AOthers
B Chemoreception
C Olfactory
D 104507005 olfactory receptor 6B1-like K04257 OLFR; olfactory receptor
D 104505209 olfactory receptor 1052-like K04257 OLFR; olfactory receptor
D 104505614 olfactory receptor-like protein OLF1 K04257 OLFR; olfactory receptor
D 104503959 olfactory receptor 1086-like K04257 OLFR; olfactory receptor
D 104507569 olfactory receptor 14J1 K04257 OLFR; olfactory receptor
D 104508193 LOW QUALITY PROTEIN: olfactory receptor 2A2-like K04257 OLFR; olfactory receptor
D 104505311 olfactory receptor 10C1-like K04257 OLFR; olfactory receptor
D 104503937 olfactory receptor 11L1 K04257 OLFR; olfactory receptor
D 104513286 olfactory receptor 2AT4 K04257 OLFR; olfactory receptor
D 104508625 olfactory receptor 52R1-like K04257 OLFR; olfactory receptor
D 104508721 LOW QUALITY PROTEIN: olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 104508831 olfactory receptor 11L1-like K04257 OLFR; olfactory receptor
D 104509117 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 104509346 olfactory receptor 14J1-like K04257 OLFR; olfactory receptor
D 104515067 olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 104515344 olfactory receptor 1440-like K04257 OLFR; olfactory receptor
D 104515345 olfactory receptor 1019-like K04257 OLFR; olfactory receptor
D 104515346 olfactory receptor 8U9-like K04257 OLFR; olfactory receptor
D 104515347 LOW QUALITY PROTEIN: olfactory receptor 1019-like K04257 OLFR; olfactory receptor
D 104510666 putative olfactory receptor 10AC1 K04257 OLFR; olfactory receptor
D 104503442 olfactory receptor 5V1-like K04257 OLFR; olfactory receptor
D 104511041 LOW QUALITY PROTEIN: olfactory receptor 1020-like K04257 OLFR; olfactory receptor
D 104506189 olfactory receptor 14I1-like K04257 OLFR; olfactory receptor
D 104511276 olfactory receptor 4D5-like K04257 OLFR; olfactory receptor
D 104511278 olfactory receptor 4S2-like K04257 OLFR; olfactory receptor
D 104511279 olfactory receptor 4S2-like K04257 OLFR; olfactory receptor
D 104511333 olfactory receptor 2A5-like K04257 OLFR; olfactory receptor
D 104516276 olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 104516277 olfactory receptor 52I2-like K04257 OLFR; olfactory receptor
D 104506668 olfactory receptor 51G2-like K04257 OLFR; olfactory receptor
D 104506669 olfactory receptor 51E2-like K04257 OLFR; olfactory receptor
D 104504407 olfactory receptor 14C36-like K04257 OLFR; olfactory receptor
D 104516745 olfactory receptor 52K2-like K04257 OLFR; olfactory receptor
D 104506691 LOW QUALITY PROTEIN: olfactory receptor 6F1-like K04257 OLFR; olfactory receptor
D 104503667 olfactory receptor 14C36-like K04257 OLFR; olfactory receptor
D 104516983 olfactory receptor 10A7-like K04257 OLFR; olfactory receptor
D 104516984 olfactory receptor 1020-like K04257 OLFR; olfactory receptor
D 104516985 LOW QUALITY PROTEIN: olfactory receptor 11L1-like K04257 OLFR; olfactory receptor
D 104516986 LOW QUALITY PROTEIN: olfactory receptor 10A2-like K04257 OLFR; olfactory receptor
D 104516987 olfactory receptor 12D3-like K04257 OLFR; olfactory receptor
D 104516988 olfactory receptor 6B1-like K04257 OLFR; olfactory receptor
C Taste
D 104507231 taste receptor type 1 member 3 K04626 TAS1R3; taste receptor type 1 member 3
D 104504020 taste receptor type 2 member 9-like K08474 TAS2R; taste receptor type 2
C Vomeronasal pheromone
C Insect odorant and taste
C Nematode chemoreception
C Fungal mating pheromone
B Others
C Ocular albinism proteins
D 104516151 GPR143; G-protein coupled receptor 143 K08470 OA1; ocular albinism type 1 protein
C Neuronostatin
D 104506645 GPR107; protein GPR107 K22985 GPR107; G protein-coupled receptor 107
C Plant Mlo receptors
C cAMP signaling
C Bacterial rhodopsin
C Orphan GPCRs
D 104513175 TPRA1; transmembrane protein adipocyte-associated 1 K22988 TPRA1; transmembrane protein adipocyte-associated 1
D 104512955 GPR137B; integral membrane protein GPR137B isoform X1 K22989 GPR137; integral membrane protein GPR137
D 104517077 GPR137C; integral membrane protein GPR137C K22989 GPR137; integral membrane protein GPR137
D 104505645 GPR157; probable G-protein coupled receptor 157 K08467 GPR157; G protein-coupled receptor 157
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 8, 2022
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Classification taken and modified from GPCRDB