+C Kinase KO
#
Protein Kinases - Escherichia coli P12b
%
!
ASerine/threonine kinases: AGC group
B PKA family
B PKG family
B PKC family [OT]
B PKN family
B AUR family [OT]
B PDK1 family
B AKT/PKB family
B SGK family [OT]
B RSK family [OT]
B NDR family
B MAST family [OT]
B YANK family
B DMPK family [OT]
B GRK family [OT]
B Other
#
ASerine/threonine kinases: CAMK group
B CAMK1 family [OT]
B CAMK2 family
B CAMKL family
B DAPK family
B DCAMKL family
B MAPKAPK family [OT]
B MLCK family
B PHK family
B PIM family [OT]
B PKD family
B PSK family
B RAD53 family
B Trio family [OT]
B TSSK family
B CDPK family
B CASK family
B Trbl family
B Other
#
ASerine/threonine kinases: CK1 group
B CK1 family [OT]
B TTBK family
B VRK family
#
ASerine/threonine kinases: CMGC group
B CDK family
B MAPK family [OT]
B GSK family [OT]
B CLK family
B CDKL family
B DYRK family [OT]
B RCK family [OT]
B SRPK family [OT]
#
ASerine/threonine kinases: STE group
B STE7 family
B STE20 family
B STE11 family
B Other
#
ASerine/threonine kinases: TKL group
B IRAK family
B LISK family [OT]
B LRRK family
B MLK family
B RAF family [OT]
B RIPK family [OT]
B Other
#
ASerine/threonine kinases: Other
B RGC family [OT]
B BUB family
B Bud32 family
B CAMKK family
B CDC7 family
B CK2 family
B Haspin family
B IKK family [OT]
B IRE family
B MOS family
B NAK family [OT]
B NEK family
B NKF1 family
B NKF2 family
B NKF3 family
B NKF4 family
B NKF5 family
B NRBP family
B PEK family [OT]
B PLK family [OT]
B SCY1 family [OT]
B Slob family
B TBCK family
B TLK family
B TOPK family
B TTK family
B ULK family [OT]
B VPS15 family
B WEE family
B Wnk family
B ABC1 family
B Alpha family [OT]
B BCR family
B BRD family [OT]
B FAST family
B G11 family
B H11 family
B PDHK family [OT]
B PIKK family [OT]
B RIO family [OT]
B TAF1 family
B TIF1 family [OT]
B Other
B Bacterial family
C P12B_c1572 hipA; regulator with hipB K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
#
AReceptor serine/threonine kinases (RSTK): TKL group
B TGFBR1 family [OT]
B TGFBR2 family [OT]
#
AReceptor tyrosine kinases (RTK)
B EGFR family [OT]
B INSR family [OT]
B PDGFR family [OT]
B FGFR family [OT]
B VEGFR family [OT]
B MET family
B TRK family [OT]
B EPH family [OT]
B AXL family
B ALK family
B TIE family
B ROR family
B DDR family
B RET family
B ROS family
B CCK family
B RYK family
B MUSK family
B LMR family [OT]
#
ANon-receptor tyrosine kinases
B ABL family
B ACK family
B CSK family
B FAK family
B FES family
B JAK family [OT]
B SRC family
B TEC family
B SYK family
B Other
B Bacterial
C P12B_c2164 Protein-tyrosine kinase K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
C P12B_c0968 yccC; Tyrosine-protein kinase etk K16692 etk-wzc; tyrosine-protein kinase Etk/Wzc [EC:2.7.10.3]
#
AHistidine kinases
B OmpR family
C P12B_c0412 phoR; Signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C P12B_c1977 phoQ; sensory histidine kinase in two-compoent regulatory system with PhoP K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C P12B_c3503 envZ; Osmolarity sensor protein envZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C P12B_c1475 rstB; sensory histidine kinase in two-component regulatory system with RstA K07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]
C P12B_c4028 cpxA; two-component sensor protein K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C P12B_c4474 creC; sensory histidine kinase in two-component regulatory system with CreB or PhoB, regulator of the CreBC regulon K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C P12B_c2181 baeS; Signal transduction histidine-protein kinase baeS K07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]
C P12B_c4215 basS; integral membrane sensor signal transduction histidine kinase K07643 basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]
C P12B_c0553 cusS; Sensor kinase cusS K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C P12B_c3593 hypothetical protein K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C P12B_c3612 hypothetical protein K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C P12B_c3126 qseC; sensory histidine kinase in two-component regulatory system with QseB K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C P12B_c0666 kdpD; fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C P12B_c0980 torS; hybrid sensory histidine kinase in two-component regulatory system with TorR K07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]
C P12B_c1055 yedV; Putative sensor-like histidine kinase yedV K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
B NarL family
C P12B_c1913 narX; Nitrate/nitrite sensor protein NarX K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3]
C P12B_c2571 narQ; Signal transduction histidine kinase, nitrate/nitrite-specific K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
C P12B_c3807 uhpB; sensory histidine kinase UhpB K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
C P12B_c2307 rcsD; Hpt sensor signal transduction histidine kinase precursor K07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]
C P12B_c2310 rcsC; sensor histidine kinase/response regulator RcsC K07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]
C P12B_c2884 barA; Signal transduction histidine-protein kinase barA K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C P12B_c2487 evgS; hybrid sensory histidine kinase in two-component regulatory system with EvgA K07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]
B Spo family [OT]
B CitB family [OT]
C P12B_c0603 citA; Sensor kinase dpiB K07700 dpiB; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]
C P12B_c4228 yjdH; sensory histidine kinase DcuS K07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]
B LytTR family [OT]
C P12B_c2223 yehU; Putative regulator of cell autolysis K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C P12B_c2499 hypothetical protein K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
B NtrC family
C P12B_c4115 zraS; Signal transduction histidine kinase K07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]
C P12B_c2657 yfhK; putative 2-component sensor protein K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
B CheA family [OT]
C P12B_c1197 cheA; Chemotaxis protein histidine kinase-like kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
B Cell cycle family [OT]
B Lux family [OT]
B LuxR family [OT]
B Other
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 3, 2024
#
Classification taken and modified from Hanks (2003)