+F Repair protein KO
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DNA Repair and Recombination Proteins - Enterococcus faecalis 7L76
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D ENT_09900 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E ENT_21400 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E ENT_13180 DNA-3-methyladenine glycosylase (3mg) K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E ENT_18710 A/G-specific DNA-adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E ENT_05810 DNA-(apurinic or apyrimidinic site) lyase/endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D ENT_05660 NUDIX domain. K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_09850 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_23230 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_29670 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_00980 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D ENT_26540 O-6-methylguanine DNA methyltransferase K13531 adaB; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D ENT_09900 Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E ENT_21400 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E ENT_24610 Uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E ENT_13180 DNA-3-methyladenine glycosylase (3mg) K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E ENT_18710 A/G-specific DNA-adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E ENT_27980 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E ENT_26530 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E ENT_22120 DNA-(apurinic or apyrimidinic site) lyase/Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E ENT_05810 DNA-(apurinic or apyrimidinic site) lyase/endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E ENT_18990 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E ENT_11420 Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E ENT_23990 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E ENT_22130 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E ENT_23380 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E ENT_23390 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E ENT_08610 Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E ENT_21560 Superfamily I DNA and RNA helicases K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ENT_24000 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ENT_22130 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E ENT_23990 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F ENT_02990 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F ENT_28700 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E ENT_29090 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E ENT_08590 MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
E ENT_27200 Mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E ENT_29080 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E ENT_21100 Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E ENT_21090 Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E ENT_30700 DNA polymerase III catalytic subunit, DnaE type K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E ENT_00570 DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E ENT_16590 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E ENT_19270 DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E ENT_19000 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E ENT_19450 DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E ENT_23990 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E ENT_21560 Superfamily I DNA and RNA helicases K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ENT_24000 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ENT_00630 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E ENT_04150 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E ENT_20470 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E ENT_03640 DNA adenine methylase (dam) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E ENT_01210 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E ENT_01220 Holliday junction DNA helicase, RuvB subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E ENT_28690 replication restart DNA helicase PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E ENT_18570 ATPase involved in DNA repair K03546 sbcC; DNA repair protein SbcC/Rad50
E ENT_18580 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E ENT_00990 DNA replication and repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E ENT_00590 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E ENT_28530 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ENT_16210 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E ENT_19300 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
E ENT_21030 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E ENT_01210 Holliday junction DNA helicase subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E ENT_01220 Holliday junction DNA helicase, RuvB subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E ENT_05350 DNA helicase/exodeoxyribonuclease V, subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E ENT_05330 DNA helicase/exodeoxyribonuclease V, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E ENT_18570 ATPase involved in DNA repair K03546 sbcC; DNA repair protein SbcC/Rad50
E ENT_18580 exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F ENT_00610 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F ENT_00600 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F ENT_22500 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F ENT_10510 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F ENT_09410 bacterial nucleoid protein Hbs K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F ENT_13780 recombinase, phage RecT family K07455 recT; recombination protein RecT
F ENT_04660 recombinase, phage RecT family K07455 recT; recombination protein RecT
F ENT_16210 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F ENT_19300 DNA replication and repair protein RecR K06187 recR; recombination protein RecR
F ENT_23990 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F ENT_16740 ATP-dependent DNA helicase, RecQ-like K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F ENT_23380 Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F ENT_23390 Excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D ENT_19200 Nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D ENT_04920 Nucleotidyltransferase/DNA polymerase involved in DNA repair K03502 umuC; DNA polymerase V
C Other SOS response factors
D ENT_21030 DNA replication and repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D ENT_00630 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ENT_04150 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ENT_20470 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D ENT_18720 Uncharacterized protein conserved in bacteria K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D ENT_15490 DnaQ family exonuclease/DinG family helicase, putative K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D ENT_05660 NUDIX domain. K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_09850 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_23230 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_29670 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ENT_00980 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D ENT_25200 ribonucleoside-diphosphate reductase class Ib beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D ENT_08230 Exopolyphosphatase-related proteins K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024