+F Repair protein KO
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DNA Repair and Recombination Proteins - Endozoicomonas sp. SCSIO W0465
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MJO57_18995 DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E MJO57_20810 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MJO57_28975 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MJO57_08235 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
E MJO57_02015 helix-hairpin-helix domain-containing protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MJO57_10460 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJO57_11380 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJO57_22455 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJO57_01195 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MJO57_18995 DNA photolyase family protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D MJO57_29130 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E MJO57_20810 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MJO57_28975 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MJO57_06595 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MJO57_06125 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MJO57_08235 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MJO57_15650 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MJO57_00295 nfo; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E MJO57_23335 nfi; deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E MJO57_13315 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MJO57_10860 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MJO57_04215 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MJO57_32290 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MJO57_06910 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E MJO57_13670 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E MJO57_15600 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E MJO57_19040 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJO57_32110 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJO57_32290 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MJO57_10860 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MJO57_04215 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MJO57_06270 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MJO57_06275 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MJO57_03930 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MJO57_31175 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MJO57_14820 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MJO57_12415 hypothetical protein K03555 mutS; DNA mismatch repair protein MutS
E MJO57_17515 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E MJO57_02975 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MJO57_23085 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E MJO57_13180 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MJO57_05065 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MJO57_17775 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MJO57_00010 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MJO57_16830 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E MJO57_06730 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MJO57_19710 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MJO57_15750 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MJO57_18880 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MJO57_10860 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MJO57_04215 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MJO57_19040 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJO57_32110 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MJO57_07175 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_07295 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_21655 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_28240 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_28780 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_31075 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_00500 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MJO57_01300 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MJO57_13370 recB; exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E MJO57_13375 recC; exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E MJO57_13365 recD; exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MJO57_22050 ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E MJO57_11870 recA; recombinase RecA K03553 recA; recombination protein RecA
E MJO57_20375 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MJO57_20370 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MJO57_20380 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MJO57_20940 RusA family crossover junction endodeoxyribonuclease K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E MJO57_25040 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MJO57_23085 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E MJO57_29385 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E MJO57_29380 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MJO57_11870 recA; recombinase RecA K03553 recA; recombination protein RecA
E MJO57_09175 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MJO57_00015 recF; DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E MJO57_31150 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MJO57_13315 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MJO57_13465 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MJO57_18870 recR; recombination mediator RecR K06187 recR; recombination protein RecR
E MJO57_06950 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MJO57_11460 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E MJO57_00505 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E MJO57_01315 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E MJO57_20375 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MJO57_20370 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MJO57_20380 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E MJO57_21015 DEAD/DEAH box helicase K19789 radD; DNA repair protein RadD
E MJO57_00215 DEAD/DEAH box helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E MJO57_29385 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E MJO57_29380 sbcD; exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MJO57_13610 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MJO57_00020 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F MJO57_14745 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F MJO57_28275 HU family DNA-binding protein K05787 hupA; DNA-binding protein HU-alpha
F MJO57_14045 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
F MJO57_17435 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MJO57_13315 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MJO57_13465 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MJO57_18870 recR; recombination mediator RecR K06187 recR; recombination protein RecR
F MJO57_10860 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F MJO57_04215 hypothetical protein K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F MJO57_24935 fis; DNA-binding transcriptional regulator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F MJO57_22725 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F MJO57_13645 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F MJO57_23085 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F MJO57_22860 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MJO57_19335 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MJO57_06910 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F MJO57_13670 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
F MJO57_28310 H-NS histone family protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MJO57_13305 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MJO57_11400 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D MJO57_00995 Y-family DNA polymerase K03502 umuC; DNA polymerase V
D MJO57_11405 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D MJO57_00970 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D MJO57_11870 recA; recombinase RecA K03553 recA; recombination protein RecA
D MJO57_14770 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D MJO57_06950 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MJO57_11610 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D MJO57_01415 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D MJO57_07175 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_07295 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_21655 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_28240 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_28780 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_31075 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_00500 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_01300 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MJO57_07875 recombination regulator RecX K03565 recX; regulatory protein
D MJO57_28615 recombination regulator RecX K03565 recX; regulatory protein
D MJO57_00960 recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MJO57_04930 rep; DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D MJO57_20730 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MJO57_10460 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJO57_11380 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJO57_22455 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MJO57_01195 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MJO57_08145 nrdA; ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MJO57_08150 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024