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Transfer RNA Biogenesis - Escherichia coli O55:H7 CB9615 (EPEC)
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D G2583_2809 rbn; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D G2583_3780 cca; TRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D G2583_4120 rtcB; RtcB protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D G2583_2934 gltX; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D G2583_0198 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D G2583_0027 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D G2583_0805 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D G2583_2650 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D G2583_0841 glnS; Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D G2583_2328 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D G2583_4956 lysU; Lysyl-tRNA synthetase, heat inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D G2583_3543 lysS; Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D G2583_2318 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D G2583_3345 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D G2583_1165 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D G2583_2166 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D G2583_1130 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D G2583_0646 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D G2583_5088 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D G2583_3038 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D G2583_2161 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D G2583_2160 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D G2583_2032 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D G2583_4081 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D G2583_4688 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D G2583_1363 hinT; hypothetical protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D G2583_3619 trmI; tRNA (Guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D G2583_0199 yaeB; hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
C Psudouridine synthases
D G2583_2855 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D G2583_3891 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D G2583_3393 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D G2583_3060 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D G2583_4001 rimN; Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D G2583_4998 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D G2583_4495 mnmE; tRNA modification GTPase trmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D G2583_4537 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D G2583_2210 selD; Selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
D G2583_5044 cysQ; PAPS (adenosine 3-phosphate 5-phosphosulfate) 3(2),5-bisphosphate nucleotidase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
C Other tRNA degradation factors
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AProkaryotic type
B 5'processing factors
C Ribonucrease P
D G2583_4493 rnpA; Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D G2583_3845 rnpB; rnpB K01978 rnpB; M1 RNA
B 3'processing and CCA adding factors
C 3'processing factors
D G2583_2809 rbn; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D G2583_2047 rnt; Ribonuclease T K03683 rnt; ribonuclease T [EC:3.1.13.-]
D G2583_4379 rph; Ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D G2583_0775 rna; Ribonuclease I K01169 rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]
D G2583_1628 rnb; Exoribonuclease 2 K01147 rnb; exoribonuclease II [EC:3.1.13.1]
D G2583_2251 rnd; Ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D G2583_3780 cca; TRNA nucleotidyltransferase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D G2583_4120 rtcB; RtcB protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D G2583_0151 ligT; hypothetical protein K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D G2583_5133 yjiI; Putative uncharacterized protein yjiI K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D G2583_5250 yjjK; Uncharacterized ABC transporter ATP-binding protein yjjK K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D G2583_0805 leuS; Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D G2583_0198 proS; Prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D G2583_2032 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D G2583_4081 trpS; Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D G2583_2166 thrS; Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D G2583_0027 ileS; Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D G2583_4956 lysU; Lysyl-tRNA synthetase, heat inducible K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D G2583_3543 lysS; Lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D G2583_3345 alaS; Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D G2583_5088 valS; Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D G2583_2650 metG; Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D G2583_1130 serS; Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D G2583_2318 aspS; Aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D G2583_4301 glyQ; Glycyl-tRNA synthetase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D G2583_4300 glyS; Glycyl-tRNA synthetase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D G2583_0646 cysS; Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D G2583_2934 gltX; Glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D G2583_0841 glnS; Glutaminyl-tRNA synthetase K01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]
D G2583_2328 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D G2583_2161 pheS; Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D G2583_2160 pheT; Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D G2583_3038 hisS; Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D G2583_1165 asnS; Asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D G2583_0148 yadB; Glutamyl-Q tRNA(Asp) synthetase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
C Trans-editing factors
D G2583_4688 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D G2583_0593 ybaK; hypothetical protein K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
D G2583_2234 yeaK; hypothetical protein K19055 prdX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D G2583_3090 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
D G2583_4873 dusA; tRNA-dihydrouridine synthase A K05539 dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]
D G2583_3979 dusB; tRNA-dihydrouridine synthase B K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D G2583_2677 dusC; tRNA-dihydrouridine synthase C K05541 dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]
C Methylthiotransferases
D G2583_0824 miaB; UPF0004 protein yleA K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D G2583_2322 cmoA; tRNA (cmo5U34)-methyltransferase K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D G2583_2323 cmoB; tRNA (mo5U34)-methyltransferase K15257 cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]
D G2583_1156 smtA; SmtA protein K06219 smtA; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]
D G2583_5262 yjtD; RNA methyltransferase, TrmH family, group 1 K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D G2583_4780 trmA; tRNA (uracil-5-)-methyltransferase (tRNA(M-5-U54)-methyltransferase) K00557 trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]
D G2583_3619 trmI; tRNA (Guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D G2583_3189 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D G2583_4495 mnmE; tRNA modification GTPase trmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D G2583_3163 yfiF; rRNA methylase K03214 yfiF; RNA methyltransferase, TrmH family [EC:2.1.1.-]
D G2583_4387 trmH; tRNA guanosine-2'-O-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D G2583_3062 trmJ; tRNA (cytidine/uridine-2'-O-)-methyltransferase trmJ K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D G2583_4345 yibK; RNA methyltransferase, TrmH family, group 2 K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D G2583_0199 yaeB; hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D G2583_3157 yfiC; Putative enzyme K15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]
C Psudouridine synthases
D G2583_2855 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D G2583_3891 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D G2583_3443 truC; tRNA pseudouridine synthase C K06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]
D G2583_3393 truD; tRNA pseudouridine synthase D K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D G2583_0061 rluA; Ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D G2583_1409 mnmA; Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D G2583_1694 ttcA; C32 tRNA thiolase K14058 ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA
D G2583_4173 sirA; Sulfurtransferase tusA K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D G2583_4048 yheL; sulfur relay protein TusD/DsrH K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D G2583_4049 yheM; hypothetical protein K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D G2583_4050 yheN; Sulfurtransferase tusD K07235 tusD; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]
D G2583_1204 yccK; Sulfurtransferase tusE K11179 tusE; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]
D G2583_3058 iscA; Iron-binding protein iscA K13628 iscA; iron-sulfur cluster assembly protein
D G2583_3060 iscS; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D G2583_3551 ygfZ; tRNA-modifying protein ygfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D G2583_4537 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D G2583_4998 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D G2583_2861 mnmC; UPF0209 protein yfcK K15461 mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]
D G2583_0514 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D G2583_0556 queC; Queuosine biosynthesis protein queC K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D G2583_3415 sscR; Putative 6-pyruvoyl tetrahydrobiopterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D G2583_3426 ygcF; hypothetical protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D G2583_3447 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase (7-cyano-7-carbaguanine reductase) (PreQ(0) reductase) K06879 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D G2583_4993 yjeS; hypothetical protein K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D G2583_2210 selD; Selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D G2583_0623 ybbB; tRNA 2-selenouridine synthase K06917 selU; tRNA 2-selenouridine synthase [EC:2.9.1.3]
D G2583_0515 tgt; Queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D G2583_0535 thiI; Thiamine biosynthesis protein thiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D G2583_0191 tilS; tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidine synthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D G2583_2997 ypfI; hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D G2583_2255 yeaZ; Glycoprotease family protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D G2583_4001 rimN; Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D G2583_3788 ygjD; Probable O-sialoglycoprotein endopeptidase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D G2583_4995 yjeE; UPF0079 ATP-binding protein yjeE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D G2583_3466 ygdL; Putative enzyme K22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase
B tRNA degradation factors
C G2583_5006 rnr; Putative enzyme K12573 rnr; ribonuclease R [EC:3.1.13.1]
C G2583_3888 pnp; Polynucleotide phosphorylase/polyadenylase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024