+F Repair protein KO
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DNA Repair and Recombination Proteins - Eremothecium cymbalariae
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E Ecym_4090 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Ecym_2637 Hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Ecym_7413 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E Ecym_6193 hypothetical protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F Ecym_5625 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F Ecym_4733 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
F Ecym_1380 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F Ecym_1099 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F Ecym_2806 Hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F Ecym_4295 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F Ecym_6281 hypothetical protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E Ecym_7458 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E Ecym_7411 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
D Other BER factors
E Ecym_3064 Hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F Ecym_7223 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F Ecym_3572 Hypothetical protein K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F Ecym_2029 Hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E NER4 complex
F Ecym_4751 hypothetical protein K15082 RAD7; DNA repair protein RAD7
F Ecym_3458 Hypothetical protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F Ecym_8065 Hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F Ecym_4538 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F Ecym_4382 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F Ecym_5193 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F Ecym_5335 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F Ecym_2818 Hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F Ecym_4540 hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F Ecym_8331 Hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F Ecym_2205 Hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F Ecym_8313 Hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F Ecym_6409 hypothetical protein K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F Ecym_2029 Hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
E Other TCR factor
F Ecym_1369 hypothetical protein K10841 ERCC6; DNA excision repair protein ERCC-6
F Ecym_7366 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E Ecym_4025 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E Ecym_3517 Hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E Ecym_3216 Hypothetical protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E Ecym_3480 Hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E Ecym_5535 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E Ecym_3371 Hypothetical protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E Ecym_7122 hypothetical protein K06634 CCNH; cyclin H
E Ecym_4115 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E Ecym_6168 hypothetical protein K07466 RFA1; replication factor A1
E Ecym_2034 Hypothetical protein K10739 RFA2; replication factor A2
D Other NER factors
E Ecym_2122 Hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E Ecym_8154 Hypothetical protein K10849 ERCC1; DNA excision repair protein ERCC-1
E Ecym_5112 hypothetical protein K10846 ERCC5; DNA excision repair protein ERCC-5
E Ecym_5405 hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E Ecym_1442 hypothetical protein K03869 CUL3; cullin 3
E Ecym_2544 Hypothetical protein K03872 ELOC; elongin-C
E Ecym_6480 hypothetical protein K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Ecym_2796 Hypothetical protein K08735 MSH2; DNA mismatch repair protein MSH2
E Ecym_6039 hypothetical protein K08736 MSH3; DNA mismatch repair protein MSH3
E Ecym_3519 Hypothetical protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E Ecym_6072 hypothetical protein K10864 PMS1; DNA mismatch repair protein PMS1
E Ecym_3383 Hypothetical protein K08734 MLH1; DNA mismatch repair protein MLH1
E Ecym_5379 hypothetical protein K10858 PMS2; DNA mismatch repair protein PMS2
E Ecym_2384 Hypothetical protein K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E Ecym_5625 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E Ecym_4733 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
E Ecym_1380 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E Ecym_6168 hypothetical protein K07466 RFA1; replication factor A1
E Ecym_2034 Hypothetical protein K10739 RFA2; replication factor A2
D RFC (replication factor C)
E Ecym_8322 Hypothetical protein K10754 RFC1; replication factor C subunit 1
E Ecym_2792 Hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E Ecym_3150 Hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E Ecym_3534 Hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
E Ecym_7452 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E Ecym_7458 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E Ecym_1331 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E Ecym_4649 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E Ecym_6250 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E Ecym_1108 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E Ecym_4761 hypothetical protein K10868 XRS2; DNA repair protein XRS2
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E Ecym_6250 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E Ecym_1108 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E Ecym_4690 hypothetical protein K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E Ecym_4690 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E Ecym_5546 hypothetical protein K10957 RAD55; DNA repair protein RAD55
E Ecym_5304 hypothetical protein K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E Ecym_4110 hypothetical protein K10873 RAD52; DNA repair and recombination protein RAD52
E Ecym_3280 Hypothetical protein K10959 RAD59; DNA repair protein RAD59
D Rad54 family proteins
E Ecym_6118 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E Ecym_2678 Hypothetical protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E Ecym_2138 Hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E Ecym_2138 Hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E Ecym_4154 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E Ecym_1401 hypothetical protein K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E Ecym_6168 hypothetical protein K07466 RFA1; replication factor A1
E Ecym_2034 Hypothetical protein K10739 RFA2; replication factor A2
D Protein phosphatase 4
E Ecym_5547 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E Ecym_6445 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E Ecym_2625 Hypothetical protein K22803 SMC5; structural maintenance of chromosomes protein 5
E Ecym_5344 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E Ecym_5076 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E Ecym_1358 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E Ecym_4745 hypothetical protein K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E Ecym_5634 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E Ecym_3485 Hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E Ecym_2318 Hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E Ecym_5526 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E Ecym_8301 Hypothetical protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E Ecym_3061 Hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E Ecym_4260 hypothetical protein K15079 SLX4; structure-specific endonuclease subunit SLX4
E Ecym_2570 Hypothetical protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E Ecym_8391 Hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E Ecym_7036 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E Ecym_6392 hypothetical protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E Ecym_4473 hypothetical protein K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
E Ecym_5069 hypothetical protein K15080 SAW1; single-strand annealing weakened protein 1
E Ecym_2336 Hypothetical protein K26124 RTT101; cullin 8
E Ecym_1440 hypothetical protein K26122 MMS22; E3 ubiquitin-protein ligase substrate receptor MMS22
E Ecym_7210 hypothetical protein K26123 MMS1; E3 ubiquitin-protein ligase linker protein MMS1
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E Ecym_4620 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E Ecym_2476 Hypothetical protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E Ecym_6250 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E Ecym_1108 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E Ecym_4761 hypothetical protein K10868 XRS2; DNA repair protein XRS2
D DNA Ligase 4 complex
E Ecym_3131 Hypothetical protein K10983 NEJ1; non-homologous end-joining protein 1
D X-family DNA polymerases
E Ecym_1342 hypothetical protein K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E Ecym_5333 hypothetical protein K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E Ecym_2138 Hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E Ecym_4154 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E Ecym_1401 hypothetical protein K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E Ecym_4690 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E Ecym_4418 hypothetical protein K11137 TELO2; telomere length regulation protein
E Ecym_5334 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E Ecym_6429 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E Ecym_4649 hypothetical protein K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Ecym_5052 hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D Ecym_2378 Hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
D Ecym_5378 hypothetical protein K03508 POLZ2; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D Ecym_3077 Hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D Ecym_2490 Hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D Ecym_2230 Hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D Ecym_5563 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D Ecym_7458 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
D Ecym_5010 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D Ecym_3515 Hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D Ecym_2792 Hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D Ecym_3150 Hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D Ecym_3534 Hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D Ecym_7452 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D Ecym_5010 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
D Ecym_3102 Hypothetical protein K02544 MEC3; G2-specific checkpoint protein
D Ecym_2218 Hypothetical protein K06663 DDC1; DNA damage checkpoint protein
C FPC (fork protection complex)
D Ecym_1083 hypothetical protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D Ecym_2288 Hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D Ecym_1008 hypothetical protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D Ecym_4418 hypothetical protein K11137 TELO2; telomere length regulation protein
C BAG6-UBL4A-GET4 complex
D Ecym_3129 Hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D Ecym_6307 hypothetical protein K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D Ecym_5624 hypothetical protein K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D Ecym_2303 Hypothetical protein K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D Ecym_3513 Hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D Ecym_2397 Hypothetical protein K02831 RAD53; ser/thr/tyr protein kinase RAD53 [EC:2.7.11.-]
D Ecym_4141 hypothetical protein K06661 RAD9; DNA repair protein RAD9
D Ecym_8129 Hypothetical protein K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D Ecym_5006 hypothetical protein K24663 NDD1; nuclear division defective protein 1
D Ecym_5396 hypothetical protein K24664 FKH; forkhead protein FKH
D Ecym_2804 Hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
D Ecym_3009 Hypothetical protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D Ecym_6059 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D Ecym_1188 hypothetical protein K17815 EXO5; exonuclease V [EC:3.1.-.-]
C Helicases
C PSO4 complex
D Ecym_8406 Hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D Ecym_6234 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D Ecym_2401 Hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D Ecym_4403 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Ecym_4318 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D Ecym_8305 Hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D Ecym_6011 hypothetical protein K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E Ecym_4090 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Ecym_6188 hypothetical protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Ecym_2637 Hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Ecym_6343 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E Ecym_6343 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D Ecym_4403 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024