+C Secretion system KO
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Secretion System - Escherichia coli O157:H7 TW14359 (EHEC)
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AType I secretion system
B alpha-Hemolysin/cyclolysin transporter
C ECSP_6019 hlyB; hemolysin transport protein K11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB/CyaB
C ECSP_6020 hlyD; hemolysin transport protein K11003 hlyD; membrane fusion protein, hemolysin D
C ECSP_4014 tolC; transport channel K12340 tolC; outer membrane protein
B RTX toxin transporter
C ECSP_4014 tolC; transport channel K12340 tolC; outer membrane protein
B Multiple protein transporter
C ECSP_4014 tolC; transport channel K12340 tolC; outer membrane protein
B Adhesin protein transporter
C ECSP_0558 putative cytoplasmic membrane export protein K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB
C ECSP_0559 putative membrane spanning export protein K12542 lapC; membrane fusion protein, adhesin transport system
C ECSP_0554 putative outer membrane export protein K12543 lapE; outer membrane protein, adhesin transport system
B RaxAB-RaxC type I secretion system protein
C ECSP_4014 tolC; transport channel K12340 tolC; outer membrane protein
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AType II secretion system
B General secretion pathway protein
C ECSP_6002 etpC; type II secretion protein K02452 gspC; general secretion pathway protein C
C ECSP_6003 etpD; type II secretion protein K02453 gspD; general secretion pathway protein D
C ECSP_6004 etpE; type II secretion protein K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
C ECSP_6005 etpF; type II secretion protein K02455 gspF; general secretion pathway protein F
C ECSP_6006 etpG; type II secretion protein K02456 gspG; general secretion pathway protein G
C ECSP_6007 etpH; type II secretion protein K02457 gspH; general secretion pathway protein H
C ECSP_6008 etpI; type II secretion protein K02458 gspI; general secretion pathway protein I
C ECSP_6009 etpJ; type II secretion protein K02459 gspJ; general secretion pathway protein J
C ECSP_6010 etpK; type II secretion protein K02460 gspK; general secretion pathway protein K
C ECSP_6011 etpL; type II secretion protein K02461 gspL; general secretion pathway protein L
C ECSP_6012 etpM; type II secretion protein K02462 gspM; general secretion pathway protein M
C ECSP_6013 etpN; type II secretion protein K02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-]
C ECSP_6014 etpO; type II secretion protein K02465 gspS; general secretion pathway protein S
B Pilin secretion/fimbrial assembly protein
C ECSP_3921 yggR; predicted transporter K02669 pilT; twitching motility protein PilT
B Tight adherence (Tad) export apparatus
B Toxin co-regulated pilus biosynthesis protein
B MSHA pilus biogenesis protein
B Type IVa pilus homolog protein
C ECSP_3778 ppdA; conserved protein K02679 ppdA; prepilin peptidase dependent protein A
C ECSP_3777 ppdB; conserved protein K02680 ppdB; prepilin peptidase dependent protein B
C ECSP_3775 ppdC; predicted protein K02681 ppdC; prepilin peptidase dependent protein C
C ECSP_0109 hcpA; type IV major pilin subunit K02682 ppdD; prepilin peptidase dependent protein D
C ECSP_0108 hcpB; conserved protein with nucleoside triphosphate hydrolase domain K02504 hofB; protein transport protein HofB
C ECSP_0107 hcpC; assembly protein in type IV pilin biogenesis, transmembrane protein K02505 hofC; protein transport protein HofC
C ECSP_4344 yrfD; predicted pilus assembly protein K12288 hofM; pilus assembly protein HofM
C ECSP_4343 yrfC; predicted fimbrial assembly protein K12289 hofN; pilus assembly protein HofN
C ECSP_4342 yrfB; hypothetical protein K12290 hofO; pilus assembly protein HofO
C ECSP_4341 yrfA; predicted protein K12291 hofP; pilus assembly protein HofP
C ECSP_4340 hofQ; predicted fimbrial transporter K02507 hofQ; protein transport protein HofQ
C ECSP_3921 yggR; predicted transporter K02669 pilT; twitching motility protein PilT
C ECSP_3923 yggT; predicted inner membrane protein K02221 yggT; YggT family protein
B Archaeal flagellar protein
B Competence-related DNA transformation transporter (DNA-T) core components
C ECSP_0510 ybaV; conserved protein K02237 comEA; competence protein ComEA
C ECSP_1017 ycaI; conserved inner membrane protein K02238 comEC; competence protein ComEC
B Competence-related DNA transformation transporter (DNA-T) related proteins
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AType III secretion system
B Type III secretion core apparatus
C ECSP_4690 escC; type III needle complex subunit K03219 yscC; type III secretion protein C
C ECSP_4673 escD; LEE-encoded type III secretion system component K03220 yscD; type III secretion protein D
C ECSP_3816 eprI; type III secretion apparatus protein EprI K03221 yscF; type III secretion protein F
C ECSP_4667 escF; LEE-encoded type III secretion system component K03221 yscF; type III secretion protein F
C ECSP_4688 escJ; LEE-encoded type III secretion system factor K03222 yscJ; type III secretion protein J
C ECSP_4683 escN; LEE-encoded type III secretion system factor K03224 yscN; ATP synthase in type III secretion protein N [EC:7.4.2.8]
C ECSP_3823 epaO; type III secretion apparatus protein K03225 yscQ; type III secretion protein Q
C ECSP_4698 escR; LEE-encoded type III secretion system factor K03226 yscR; type III secretion protein R
C ECSP_4697 escS; LEE-encoded type III secretion system factor K03227 yscS; type III secretion protein S
C ECSP_4696 escT; LEE-encoded type III secretion system factor K03228 yscT; type III secretion protein T
C ECSP_4695 escU; LEE-encoded type III secretion system factor K03229 yscU; type III secretion protein U
C ECSP_3828 eivA; type III secretion apparatus protein K03230 yscV; type III secretion protein V
C ECSP_4684 escV; LEE-encoded type III secretion system factor K03230 yscV; type III secretion protein V
C ECSP_3830 eivG; type III secretion apparatus protein K22504 invG; type III secretion system outer membrane ring protein
C ECSP_3814 eprK; putative lipoprotein of type III secretion apparatus K22505 prgK; type III secretion system inner membrane ring protein
C ECSP_3827 eivC; type III secretion apparatus protein K22506 spaL; type III secretion system ATPase [EC:7.4.2.8]
C ECSP_3822 epaP; putative integral membrane protein-component of typeIII secretion apparatus K22507 spaP; type III secretion system export apparatus protein
C ECSP_3821 epaQ; type III secretion apparatus protein K22508 spaQ; type III secretion system export apparatus protein
C ECSP_3819 epaS; putative integral membrane protein-component of type III secretion apparatus K22510 spaS; type III secretion system export apparatus switch protein
C ECSP_3829 eivE; putative secreted protein K22511 invE; type III secretion system protein
B Type III secretion related proteins
C ECSP_3826 eivI; type III secretion apparatus protein K22513 spaM; type III secretion system protein
C ECSP_3824 eivJ; type III secretion apparatus protein K22514 spaN; type III secretion system protein
C ECSP_3815 eprJ; putative Type III secretion apparatus protein K22487 prgJ; type III secretion system protein
B Flagellar export apparatus
C ECSP_2453 flhA; predicted flagellar export pore protein K02400 flhA; flagellar biosynthesis protein FlhA
C ECSP_0263 Flagellar component K02400 flhA; flagellar biosynthesis protein FlhA
C ECSP_2454 flhB; predicted flagellar export pore protein K02401 flhB; flagellar biosynthesis protein FlhB
C ECSP_2542 fliF; flagellar basal-body MS-ring and collar protein K02409 fliF; flagellar M-ring protein FliF
C ECSP_2544 fliH; flagellar biosynthesis protein K02411 fliH; flagellar assembly protein FliH
C ECSP_2545 fliI; flagellum-specific ATP synthase K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]
C ECSP_2550 fliN; flagellar motor switching and energizing component K02417 fliN; flagellar motor switch protein FliN
C ECSP_2551 fliO; flagellar biosynthesis protein K02418 fliO; flagellar protein FliO/FliZ
C ECSP_2552 fliP; flagellar biosynthesis protein K02419 fliP; flagellar biosynthesis protein FliP
C ECSP_2553 fliQ; flagellar biosynthesis protein K02420 fliQ; flagellar biosynthesis protein FliQ
C ECSP_2554 fliR; flagellar export pore protein K02421 fliR; flagellar biosynthesis protein FliR
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AType IV secretion system
B Conjugal DNA-protein transfer (VirB/D) protein
B DNA uptake competence system protein
B Conjugal transfer pilus assembly protein
C ECSP_3861 dsbC; protein disulfide isomerase II K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
B Pertussis toxin exporter
B Cag pathogenicity island (PAI) protein
B Icm/Dot secretion system protein
B Trb secretion system protein
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AType V secretion system
B Autotransporter-1 (AT-1) family
C ECSP_0370 putative beta-barrel outer membrane protein K12678 aidA-I; autotransporter family porin
C ECSP_1995 ydeK; predicted lipoprotein K12678 aidA-I; autotransporter family porin
C ECSP_3106 yfaL; adhesin K07279 yfaL; autotransporter family porin
C ECSP_6096 espP; putative exoprotein-precursor K12684 esp; serine protease autotransporter [EC:3.4.21.-]
C ECSP_1883 autotransporter-1 (AT-1) family protein K12516 bigA; putative surface-exposed virulence protein
C ECSP_1882 hypothetical protein K12516 bigA; putative surface-exposed virulence protein
C ECSP_1319 cah; calcium-binding autotransporter K12687 flu; antigen 43
B Autotransporter-2 (AT-2) family
B Two-partner secretion (TPS) family
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AType VI secretion system
B Imp/Vas secretion system core components
C ECSP_0223 putative macrophage toxin K11891 impL; type VI secretion system protein ImpL
C ECSP_0227 predicted protein K11892 impK; type VI secretion system protein ImpK
C ECSP_0228 predicted protein K11893 impJ; type VI secretion system protein ImpJ
C ECSP_0231 predicted protein K11895 impH; type VI secretion system protein ImpH
C ECSP_0232 predicted protein K11896 impG; type VI secretion system protein ImpG
C ECSP_0234 predicted protein K11900 impC; type VI secretion system protein ImpC
C ECSP_0236 predicted protein K11901 impB; type VI secretion system protein ImpB
C ECSP_0238 predicted protein K11903 hcp; type VI secretion system secreted protein Hcp
C ECSP_0240 predicted protein K11904 vgrG; type VI secretion system secreted protein VgrG
C ECSP_0621 predicted protein K11904 vgrG; type VI secretion system secreted protein VgrG
C ECSP_1938 vgrE; hypothetical protein K11904 vgrG; type VI secretion system secreted protein VgrG
C ECSP_0233 predicted protein K11905 K11905; type VI secretion system protein
C ECSP_0229 predicted protein K11906 vasD; type VI secretion system protein VasD
C ECSP_0226 clpV; Hsp100/Clp ATPase K11907 vasG; type VI secretion system protein VasG
C ECSP_0224 ImpA domain protein K11910 vasJ; type VI secretion system protein VasJ
C ECSP_0222 predicted protein K11911 vasL; type VI secretion system protein VasL
B Imp/Vas secretion system related proteins
C ECSP_0230 predicted protein K11894 impI; type VI secretion system protein ImpI
C ECSP_0225 predicted protein K11909 vasI; type VI secretion system protein VasI
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AType VII secretion system
B ESX secretion system protein
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AChaperone-usher system
B Type 1 pilus assembly protein
C ECSP_1205 putative pilin subunit K07345 fimA; major type 1 subunit fimbrin (pilin)
C ECSP_1992 fmlA; major subunit of F9 fimbriae K07345 fimA; major type 1 subunit fimbrin (pilin)
C ECSP_5398 fimA; major type 1 subunit fimbrin (pilin) K07345 fimA; major type 1 subunit fimbrin (pilin)
C ECSP_4777 lpfA2; putative major fimbrial subunit K07345 fimA; major type 1 subunit fimbrin (pilin)
C ECSP_1991 fmlB; F9 fimbriae chaperone K07346 fimC; fimbrial chaperone protein
C ECSP_5400 fimC; periplasmic chaperone, required for type 1 fimbriae K07346 fimC; fimbrial chaperone protein
C ECSP_1044 ycbR; predicted periplasmic pilin chaperone K07346 fimC; fimbrial chaperone protein
C ECSP_1204 putative chaperone K07346 fimC; fimbrial chaperone protein
C ECSP_4541 lpfB; putative fimbrial chaperone K07346 fimC; fimbrial chaperone protein
C ECSP_1990 fmlC; F9 fimbriae usher protein K07347 fimD; outer membrane usher protein
C ECSP_1203 putative usher protein K07347 fimD; outer membrane usher protein
C ECSP_0140 htrE; putative fimbrial usher protein K07347 fimD; outer membrane usher protein
C ECSP_2908 yehB; predicted outer membrane protein K07347 fimD; outer membrane usher protein
C ECSP_5401 fimD; outer membrane usher protein, type 1 fimbrial synthesis K07347 fimD; outer membrane usher protein
C ECSP_4118 yraJ; predicted outer membrane protein K07347 fimD; outer membrane usher protein
C ECSP_4774 lpfC; fimbrial usher K07347 fimD; outer membrane usher protein
C ECSP_5402 fimF; fimbrial morphology K07348 fimF; minor fimbrial subunit
C ECSP_5403 fimG; minor subunit of type 1 fimbriae K07349 fimG; minor fimbrial subunit
C ECSP_1988 ydeR; putative F9 fimbriae protein K07349 fimG; minor fimbrial subunit
C ECSP_5404 fimH; minor fimbrial subunit, D-mannose specific adhesin K07350 fimH; minor fimbrial subunit
B P pilus assembly protein
C ECSP_3212 yfcU; putative fimbrial usher K12518 papC; outer membrane usher protein PapC
C ECSP_3211 yfcS; predicted periplasmic pilus chaperone K12519 papD; chaperone protein PapD
B Mat/Ecp fimbriae assembly protein
C ECSP_0330 ecpA; Mat fimbrillin K21964 ecpA; Mat/Ecp fimbriae major subunit
C ECSP_0329 ecpB; predicted chaperone K21965 ecpB; Mat/Ecp fimbriae periplasmic chaperone
C ECSP_0328 ecpC; predicted usher protein K21966 ecpC; Mat/Ecp fimbriae outer membrane usher protein
C ECSP_0327 yagW; predicted receptor K21967 ecpD; Mat/Ecp fimbriae adhesin
C ECSP_0326 ecpE; predicted chaperone K21968 ecpE; Mat/Ecp fimbriae periplasmic chaperone
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AExtracellular nucleation-precipitation pathway
B Curli assembly protein
C ECSP_1344 csgA; cryptic curlin major subunit K04334 csgA; major curlin subunit
C ECSP_1343 csgB; curlin nucleator protein, minor subunit in curli complex K04335 csgB; minor curlin subunit
C ECSP_1345 csgC; predicted curli production protein K04336 csgC; curli production protein
C ECSP_1340 csgE; predicted transport protein K04337 csgE; curli production assembly/transport component CsgE
C ECSP_1339 csgF; predicted transport protein K04338 csgF; curli production assembly/transport component CsgF
C ECSP_1338 csgG; curli production assembly/transport component, 2nd curli operon K06214 csgG; curli production assembly/transport component CsgG
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ASec (secretion) system
B Prokaryotic Sec-SRP core components
C ECSP_0101 secA; preprotein translocase subunit, ATPase K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
C ECSP_4606 secB; protein export chaperone K03071 secB; preprotein translocase subunit SecB
C ECSP_0473 secD; SecYEG protein translocase auxillary subunit K03072 secD; preprotein translocase subunit SecD
C ECSP_5051 secE; preprotein translocase membrane subunit K03073 secE; preprotein translocase subunit SecE
C ECSP_0474 secF; SecYEG protein translocase auxillary subunit K03074 secF; preprotein translocase subunit SecF
C ECSP_4150 secG; preprotein translocase membrane subunit K03075 secG; preprotein translocase subunit SecG
C ECSP_0100 secM; regulator of secA translation K13301 secM; secretion monitor
C ECSP_4271 secY; preprotein translocase membrane subunit K03076 secY; preprotein translocase subunit SecY
C ECSP_3555 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C ECSP_4420 ftsY; membrane-binding signal recognition particle (SRP) receptor K03110 ftsY; fused signal recognition particle receptor
C ECSP_0472 yajC; SecYEG protein translocase auxillary subunit K03210 yajC; preprotein translocase subunit YajC
C ECSP_4751 yidC; cytoplasmic insertase into membrane protein, Sec system K03217 yidC; YidC/Oxa1 family membrane protein insertase
B Prokaryotic Sec-SRP related proteins
B Eukaryotic Sec-SRP protein
C ECSP_3555 ffh; Signal Recognition Particle (SRP) component with 4.5S RNA (ffs) K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
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ATwin-arginine translocation (Tat) system
B Twin-arginine translocation (Tat) pathway protein
C ECSP_4891 tatA; component of Sec-independent translocase K03116 tatA; sec-independent protein translocase protein TatA
C ECSP_4892 tatB; component of Sec-independent translocase K03117 tatB; sec-independent protein translocase protein TatB
C ECSP_4893 tatC; component of Sec-independent translocase K03118 tatC; sec-independent protein translocase protein TatC
C ECSP_0680 tatE; component of Sec-independent translocase K03425 tatE; sec-independent protein translocase protein TatE
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 11, 2023