+F Repair protein KO
#
DNA Repair and Recombination Proteins - Folsomia candida
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 110860538 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D 110845488 activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
C BER (base exicision repair)
D DNA glycosylases
E 110851825 uncharacterized protein LOC110851825 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110858922 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110859143 AT-rich interactive domain-containing protein 1B-like K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E 110854703 uncharacterized protein LOC110854703 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 110861535 N-glycosylase/DNA lyase-like K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 110851166 endonuclease III-like protein 1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 110852854 recombination repair protein 1-like K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E 110862814 DNA-(apurinic or apyrimidinic site) lyase 2-like K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 110852860 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 110848366 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 110848412 DNA polymerase delta small subunit-like K02328 POLD2; DNA polymerase delta subunit 2
F 110847982 DNA polymerase delta subunit 2-like isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
F 110852809 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
F 110846479 uncharacterized protein LOC110846479 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F 110842609 DNA polymerase epsilon catalytic subunit A-like K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 110845226 DNA polymerase epsilon subunit 2-like K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 110848791 DNA polymerase epsilon subunit 3-like K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E 110848142 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 110851403 flap endonuclease 1-like K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E 110859298 DNA repair protein XRCC1-like K10803 XRCC1; DNA-repair protein XRCC1
D Other BER factors
E 110853072 probable tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 110855993 uncharacterized protein F21D5.5-like K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 110851183 high mobility group protein DSP1-like K10802 HMGB1; high mobility group protein B1
E 110852331 poly [ADP-ribose] polymerase 1-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 110851751 poly [ADP-ribose] polymerase-like K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E 110852166 poly [ADP-ribose] polymerase 2-like K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 110850628 DNA repair protein complementing XP-C cells homolog K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 110846188 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 110848901 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 110844599 cullin-4B-like K10609 CUL4; cullin 4
F 110844766 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 110853733 DNA damage-binding protein 2-like K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 110856304 DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 110856691 DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 110858786 DNA-directed RNA polymerase II subunit RPB1-like K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 110855890 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 110854205 DNA-directed RNA polymerase II subunit RPB2-like K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 110863512 DNA-directed RNA polymerase II subunit RPB3-like K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 110846247 DNA-directed RNA polymerase II subunit RPB4-like K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 110861498 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 110846564 DNA-directed RNA polymerases I, II, and III subunit RPABC2-like K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 110843593 DNA-directed RNA polymerase II subunit RPB7-like K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 110843124 DNA-directed RNA polymerases I, II, and III subunit RPABC3-like isoform X1 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 110854149 DNA-directed RNA polymerase II subunit RPB9-like K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 110856194 DNA-directed RNA polymerase II subunit RPB11-like K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
E Cul4-CSA complex
F 110848901 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 110844599 cullin-4B-like K10609 CUL4; cullin 4
F 110844766 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
F 110853842 DNA excision repair protein ERCC-8-like K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 110844241 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
F 110844226 UV-stimulated scaffold protein A-like K23720 UVSSA; UV-stimulated scaffold protein A
F 110852031 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 110855824 DNA excision repair protein haywire-like K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 110843072 TFIIH basal transcription factor complex helicase XPD subunit-like K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 110844561 general transcription factor IIH subunit 1-like K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 110852529 general transcription factor IIH subunit 2-like K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 110846386 general transcription factor IIH subunit 3-like K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 110856157 general transcription factor IIH subunit 4-like K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 110841809 cyclin-dependent kinase 7-like K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 110845429 cyclin-H-like K06634 CCNH; cyclin H
E 110863581 CDK-activating kinase assembly factor MAT1-like K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 110841823 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 110844251 replication protein A 32 kDa subunit-B-like K10739 RFA2; replication factor A2
E 110861523 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Other NER factors
E 110842522 DNA repair protein complementing XP-A cells-like K10847 XPA; DNA-repair protein complementing XP-A cells
E 110863375 DNA excision repair protein ERCC-1-like K10849 ERCC1; DNA excision repair protein ERCC-1
E 110846254 DNA repair endonuclease XPF-like K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 110859972 DNA repair protein complementing XP-G cells homolog K10846 ERCC5; DNA excision repair protein ERCC-5
E 110854261 MMS19 nucleotide excision repair protein homolog isoform X1 K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 110862416 cullin-3-like isoform X1 K03869 CUL3; cullin 3
E 110843918 cullin-3-A-like K03869 CUL3; cullin 3
E 110854322 cullin-5-like K10612 CUL5; cullin 5
E 110842121 elongin-C K03872 ELOC; elongin-C
E 110847556 elongin-B-like K03873 ELOB; elongin-B
E 110846237 transcription elongation factor B polypeptide 3-like K15076 ELOA; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 110845892 DNA mismatch repair protein Msh2-like K08735 MSH2; DNA mismatch repair protein MSH2
E 110851254 DNA mismatch repair protein Msh6-like K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 110862605 DNA mismatch repair protein Mlh1-like K08734 MLH1; DNA mismatch repair protein MLH1
E 110858656 mismatch repair endonuclease PMS2-like K10858 PMS2; DNA mismatch repair protein PMS2
E 110844022 mismatch repair endonuclease pms1-like K08739 MLH3; DNA mismatch repair protein MLH3
E 110854040 DNA mismatch repair protein Mlh3-like K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E 110852860 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 110848366 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 110848412 DNA polymerase delta small subunit-like K02328 POLD2; DNA polymerase delta subunit 2
E 110847982 DNA polymerase delta subunit 2-like isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
E 110852809 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E 110846479 uncharacterized protein LOC110846479 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E 110841823 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 110844251 replication protein A 32 kDa subunit-B-like K10739 RFA2; replication factor A2
E 110861523 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 110849337 replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 110852026 LOW QUALITY PROTEIN: replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 110862325 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
E 110848312 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 110848926 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
E 110860501 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 110848142 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
E 110844361 exonuclease 1-like isoform X1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 110851183 high mobility group protein DSP1-like K10802 HMGB1; high mobility group protein B1
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 110851732 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 110842929 nibrin-like K10867 NBN; nibrin
D BRCA1-core complex
E 110847665 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
D BRCA1-B complex
E 110843548 Fanconi anemia group J protein homolog K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 110847580 Fanconi anemia group J protein homolog K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 110848059 DNA topoisomerase 2-binding protein 1-like K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 110851732 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 110842929 nibrin-like K10867 NBN; nibrin
D BRCA complex
E 110854824 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
E 110859168 DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 110854824 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
E 110859168 DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
E 110845609 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 110847995 DNA repair protein RAD51 homolog 4-like K10871 RAD51L3; RAD51-like protein 3
E 110842847 DNA repair protein XRCC3 homolog isoform X1 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 110853157 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 110853758 helicase ARIP4-like K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
D RecQ family DNA helicases
E 110851930 ATP-dependent DNA helicase Q1-like K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 110845832 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110863067 ATP-dependent DNA helicase Q4-like K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 110845832 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110848408 DNA topoisomerase 3-alpha-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110850696 DNA topoisomerase 3-beta-1-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110853839 recQ-mediated genome instability protein 1-like K10990 RMI1; RecQ-mediated genome instability protein 1
E 110862145 uncharacterized protein LOC110862145 K15365 RMI2; RecQ-mediated genome instability protein 2
D RPA (replication factor A)
E 110841823 replication protein A 70 kDa DNA-binding subunit-like isoform X1 K07466 RFA1; replication factor A1
E 110844251 replication protein A 32 kDa subunit-B-like K10739 RFA2; replication factor A2
E 110861523 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 110860705 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 110855799 serine/threonine-protein phosphatase 4 regulatory subunit 1-like K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 110860531 serine/threonine-protein phosphatase 4 regulatory subunit 2-like K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 110844440 serine/threonine-protein phosphatase 4 regulatory subunit 3A-like isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E 110843958 structural maintenance of chromosomes protein 5-like K22803 SMC5; structural maintenance of chromosomes protein 5
E 110848505 structural maintenance of chromosomes protein 6-like K22804 SMC6; structural maintenance of chromosomes protein 6
E 110852886 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 110848199 uncharacterized protein LOC110848199 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 110845199 uncharacterized protein LOC110845199 K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 110844519 E3 SUMO-protein ligase MMS21-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E 110852092 EP300-interacting inhibitor of differentiation 3-like K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E 110854566 crossover junction endonuclease EME1-like K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 110843870 crossover junction endonuclease MUS81-like K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 110848095 26S proteasome complex subunit SEM1-like K10881 SHFM1; 26 proteasome complex subunit DSS1
E 110861764 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 110849742 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 110842219 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 110857712 deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 110852801 fidgetin-like protein 1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 110848761 uncharacterized protein LOC110848761 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein
E 110853184 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 110845974 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 110852182 X-ray repair cross-complementing protein 6-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 110843047 DNA-dependent protein kinase catalytic subunit-like K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 110851732 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E 110860598 DNA ligase 4-like K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
D Other NHEJ factors
E 110852919 protein artemis-like K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E 110842397 tyrosyl-DNA phosphodiesterase 2-like K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 110849979 tyrosyl-DNA phosphodiesterase 2-like isoform X1 K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E 110859954 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 110848345 uncharacterized protein LOC110848345 K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 110861719 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
E 110859636 structural maintenance of chromosomes flexible hinge domain-containing protein 1-like K23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
C FA (Fanconi anemia) pathway
D FA core complex
E 110855857 Fanconi anemia group A protein homolog K10888 FANCA; fanconi anemia group A protein
E 110844554 E3 ubiquitin-protein ligase FANCL-like isoform X1 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E 110859893 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 110845832 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 110848408 DNA topoisomerase 3-alpha-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110850696 DNA topoisomerase 3-beta-1-like K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 110853839 recQ-mediated genome instability protein 1-like K10990 RMI1; RecQ-mediated genome instability protein 1
E 110862145 uncharacterized protein LOC110862145 K15365 RMI2; RecQ-mediated genome instability protein 2
D FANCD2-I complex
E 110847458 uncharacterized protein LOC110847458 K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 110843548 Fanconi anemia group J protein homolog K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E 110847580 Fanconi anemia group J protein homolog K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 110841681 fanconi-associated nuclease 1-like K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 110854824 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
E 110859168 DNA repair protein RAD51 homolog 1-like K04482 RAD51; DNA repair protein RAD51
E 110845609 DNA repair protein RAD51 homolog 3-like K10870 RAD51L2; RAD51-like protein 2
E 110853614 WD repeat-containing protein 48-like K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 110847788 serine/threonine-protein phosphatase 6 catalytic subunit-like K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
E 110844946 E3 ubiquitin-protein ligase CHFR-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 110843566 E3 ubiquitin-protein ligase HERC2-like K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 110858411 telomerase Cajal body protein 1-like K23314 WRAP53; telomerase Cajal body protein 1
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 110855902 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 110860060 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 110860129 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 110863434 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 110863111 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 110855868 DNA polymerase eta-like K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 110858005 DNA polymerase kappa-like K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D 110843154 DNA repair protein REV1-like K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 110842958 DNA polymerase zeta catalytic subunit-like K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D 110844087 ubiquitin-conjugating enzyme E2 2-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110851798 ubiquitin-conjugating enzyme E2-17 kDa-like K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110850717 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 110846273 ubiquitin-conjugating enzyme E2 variant 2-like K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 110858075 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 110848142 proliferating cell nuclear antigen-like K04802 PCNA; proliferating cell nuclear antigen
D 110861791 sprT-like domain-containing protein Spartan K24051 SPRTN; SprT-like domain-contaning protein Spartan
B Check point factors
C Rad9-Hus1-Rad1 complex
D 110850708 cell cycle checkpoint control protein RAD9B-like K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 110844550 checkpoint protein HUS1-like K10903 HUS1; HUS1 checkpoint protein
D 110851236 uncharacterized protein LOC110851236 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 110846456 cell cycle checkpoint protein RAD17-like K06662 HRAD17; cell cycle checkpoint protein
D 110862325 replication factor C subunit 4-like K10755 RFC2_4; replication factor C subunit 2/4
D 110848312 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 110848926 replication factor C subunit 3-like K10756 RFC3_5; replication factor C subunit 3/5
D 110860501 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 110851236 uncharacterized protein LOC110851236 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 110856215 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 110856354 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 110842525 protein TIPIN homolog K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D 110853569 uncharacterized protein LOC110853569 K20403 TTI1; TELO2-interacting protein 1
D 110848212 uncharacterized protein LOC110848212 K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D 110859751 large proline-rich protein bag6-like K23390 BAG6; large proline-rich protein BAG6
D 110853610 uncharacterized protein LOC110853610 K23388 UBL4; ubiquitin-like protein 4
D 110846418 Golgi to ER traffic protein 4 homolog B-like K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 110853227 serine/threonine-protein kinase ATR-like K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 110850413 serine-protein kinase ATM-like K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 110845196 serine/threonine-protein kinase Chk1-like isoform X1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 110858128 M-phase inducer phosphatase-like K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 110847971 14-3-3 protein zeta isoform X1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 110842481 14-3-3 protein epsilon isoform X1 K06630 YWHAE; 14-3-3 protein epsilon
D 110846638 plastin-1-like K17336 PLS3; plastin-3
D 110851297 plastin-3-like K17336 PLS3; plastin-3
D 110858515 protein downstream neighbor of Son-like K22422 DONSON; protein downstream neighbor of Son
D 110858044 KN motif and ankyrin repeat domain-containing protein 2-like K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 110855466 suppressor protein of bem1/bed5 double mutants-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110842726 probable spastin homolog Bm1_53365 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110856064 vacuolar protein sorting-associated protein 4A-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110855165 vacuolar protein sorting-associated protein 4-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110855199 vacuolar protein sorting-associated protein 4A-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110860986 suppressor protein of bem1/bed5 double mutants-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110859958 vacuolar protein sorting-associated protein 4A-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110859566 vacuolar protein sorting-associated protein 4A-like isoform X1 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110845575 suppressor protein of bem1/bed5 double mutants-like K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 110845094 abscission/NoCut checkpoint regulator-like K24778 ZFYVE19; abscission/NoCut checkpoint regulator
B Other factors with a suspected DNA repair function
C DNA polymerases
D 110842693 DNA polymerase theta-like K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 110848237 uncharacterized protein LOC110848237 K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D 110846379 DNA cross-link repair protein SNM1-like K15340 DCLRE1A; DNA cross-link repair 1A protein
D 110848897 endonuclease V-like K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D 110859841 uncharacterized protein LOC110859841 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
C PSO4 complex
D 110850093 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 110847738 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 110849349 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 110846100 pleiotropic regulator 1-like K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 110849332 7,8-dihydro-8-oxoguanine triphosphatase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 110849535 7,8-dihydro-8-oxoguanine triphosphatase-like K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D 110854416 8-oxo-dGDP phosphatase NUDT18-like K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 110854828 probable deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110856494 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110860732 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110855534 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110855537 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110856531 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110861249 uncharacterized protein LOC110861249 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110854471 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110850520 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110850557 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110858915 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110848067 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110853235 probable deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110851853 ribonucleoside-diphosphate reductase large subunit-like K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 110852546 ribonucleoside-diphosphate reductase small chain-like K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 110860538 methylated-DNA--protein-cysteine methyltransferase-like K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E 110851825 uncharacterized protein LOC110851825 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110858922 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 110854703 uncharacterized protein LOC110854703 K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 110851166 endonuclease III-like protein 1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 110851520 single-stranded DNA-binding protein, mitochondrial-like K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 110851520 single-stranded DNA-binding protein, mitochondrial-like K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 110854828 probable deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110856494 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110860732 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110855534 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110855537 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110856531 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110861249 uncharacterized protein LOC110861249 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110854471 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110850520 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110850557 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110858915 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110848067 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 110853235 probable deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024