+F Repair protein KO
#
DNA Repair and Recombination Proteins - Fulvia fulva
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CLAFUR5_07556 uncharacterized protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CLAFUR5_04668 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D CLAFUR5_14317 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E CLAFUR5_12688 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CLAFUR5_04044 G/U mismatch-specific uracil DNA glycosylase K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E CLAFUR5_08331 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E CLAFUR5_00181 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E CLAFUR5_08826 Apurinic-apyrimidinic endonuclease 1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E CLAFUR5_14201 DNA-(apurinic or apyrimidinic site) endonuclease 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F CLAFUR5_03510 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F CLAFUR5_10931 DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
E DNA polymerase epsilon complex
F CLAFUR5_12615 DNA polymerase epsilon catalytic subunit A K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F CLAFUR5_09219 DNA polymerase epsilon subunit B K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
E CLAFUR5_08152 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E CLAFUR5_09801 Flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E CLAFUR5_00223 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
D Other BER factors
E CLAFUR5_03493 Aprataxin-like protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CLAFUR5_02139 Poly [ADP-ribose] polymerase 2 K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F CLAFUR5_08356 DNA repair protein rhp42 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F CLAFUR5_00089 DNA repair protein rhp41 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F CLAFUR5_03313 UV excision repair protein rhp23 K10839 RAD23; UV excision repair protein RAD23
F CLAFUR5_08562 uncharacterized protein K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F CLAFUR5_07092 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CLAFUR5_02513 Cullin-4B K10609 CUL4; cullin 4
F CLAFUR5_11465 DNA damage-binding protein 1A K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F CLAFUR5_00675 DNA repair protein rhp7 K15082 RAD7; DNA repair protein RAD7
F CLAFUR5_07285 DNA repair protein RAD16 K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F CLAFUR5_04361 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F CLAFUR5_11724 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F CLAFUR5_02210 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F CLAFUR5_00590 DNA-directed RNA polymerase II subunit rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F CLAFUR5_08934 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F CLAFUR5_01178 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F CLAFUR5_00790 DNA-directed RNA polymerase II subunit rpb7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F CLAFUR5_11549 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F CLAFUR5_06043 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F CLAFUR5_07201 DNA-directed RNA polymerase subunit N K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F CLAFUR5_10088 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F CLAFUR5_04988 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F CLAFUR5_01276 DNA-directed RNA polymerases II, IV and V subunit 12 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F CLAFUR5_07092 E3 ubiquitin-protein ligase RBX1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F CLAFUR5_02513 Cullin-4B K10609 CUL4; cullin 4
F CLAFUR5_11465 DNA damage-binding protein 1A K10610 DDB1; DNA damage-binding protein 1
F CLAFUR5_12339 DNA excision repair protein ckn1 K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F CLAFUR5_10446 DNA repair protein rhp26 K10841 ERCC6; DNA excision repair protein ERCC-6
F CLAFUR5_04150 Transcription elongation factor 1 K25829 ELOF1; transcription elongation factor 1
F CLAFUR5_07126 Transcription elongation factor 1 K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E CLAFUR5_07500 General transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E CLAFUR5_09291 General transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E CLAFUR5_06520 General transcription and DNA repair factor IIH subunit tcf-29 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E CLAFUR5_03283 General transcription and DNA repair factor IIH subunit ssl1 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E CLAFUR5_11527 General transcription and DNA repair factor IIH subunit tfb4 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E CLAFUR5_10007 General transcription and DNA repair factor IIH subunit TFB2 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E CLAFUR5_04141 General transcription and DNA repair factor IIH subunit TFB5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E CLAFUR5_04836 Serine/threonine-protein kinase crk1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E CLAFUR5_07281 Cyclin CCL1 K06634 CCNH; cyclin H
E CLAFUR5_00721 RNA polymerase II transcription factor B subunit 3 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E CLAFUR5_09807 Replication factor A protein 1 K07466 RFA1; replication factor A1
E CLAFUR5_11041 Replication factor A protein 2 K10739 RFA2; replication factor A2
E CLAFUR5_02807 Replication factor A protein 3 K10740 RPA3; replication factor A3
D Other NER factors
E CLAFUR5_06914 DNA repair protein RAD14 K10847 XPA; DNA-repair protein complementing XP-A cells
E CLAFUR5_00653 Mating-type switching protein swi10 K10849 ERCC1; DNA excision repair protein ERCC-1
E CLAFUR5_01952 DNA repair protein rad16 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E CLAFUR5_01615 DNA repair protein rad13 K10846 ERCC5; DNA excision repair protein ERCC-5
E CLAFUR5_00223 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CLAFUR5_01636 MMS19 nucleotide excision repair K15075 MET18; DNA repair/transcription protein MET18/MMS19
E CLAFUR5_08902 Cullin-3 K03869 CUL3; cullin 3
E CLAFUR5_11298 Elongin-C K03872 ELOC; elongin-C
E CLAFUR5_09200 uncharacterized protein K15077 ELA1; elongin-A
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E CLAFUR5_09392 DNA mismatch repair protein msh-2 K08735 MSH2; DNA mismatch repair protein MSH2
E CLAFUR5_12366 DNA mismatch repair protein MSH3 K08736 MSH3; DNA mismatch repair protein MSH3
E CLAFUR5_02015 DNA mismatch repair protein msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E CLAFUR5_11551 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E CLAFUR5_02465 Mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
E CLAFUR5_13733 DNA mismatch repair protein MLH3 K08739 MLH3; DNA mismatch repair protein MLH3
D DNA polymerase delta complex
E CLAFUR5_03510 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E CLAFUR5_10931 DNA polymerase delta subunit 4 K03505 POLD4; DNA polymerase delta subunit 4
D RPA (replication factor A)
E CLAFUR5_09807 Replication factor A protein 1 K07466 RFA1; replication factor A1
E CLAFUR5_11041 Replication factor A protein 2 K10739 RFA2; replication factor A2
E CLAFUR5_02807 Replication factor A protein 3 K10740 RPA3; replication factor A3
D RFC (replication factor C)
E CLAFUR5_00600 Replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E CLAFUR5_03647 Replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E CLAFUR5_07906 Replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E CLAFUR5_02060 Replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
E CLAFUR5_06648 Replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E CLAFUR5_08152 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E CLAFUR5_12810 Exodeoxyribonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E CLAFUR5_00223 DNA ligase 1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E CLAFUR5_09195 DNA damage-binding protein CMR1 K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E CLAFUR5_11193 Double-strand break repair protein mus-23 K10865 MRE11; double-strand break repair protein MRE11
E CLAFUR5_11902 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
E CLAFUR5_11193 Double-strand break repair protein mus-23 K10865 MRE11; double-strand break repair protein MRE11
E CLAFUR5_11902 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E CLAFUR5_01236 DNA repair protein rhp51 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E CLAFUR5_01236 DNA repair protein rhp51 K04482 RAD51; DNA repair protein RAD51
E CLAFUR5_03835 DNA repair protein rhp57 K10958 RAD57; DNA repair protein RAD57
D Rad52 family proteins
E CLAFUR5_13480 DNA repair and recombination protein rhm52 K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E CLAFUR5_09300 DNA repair protein rhp54 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E CLAFUR5_03678 DNA repair and recombination protein RAD54B K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E CLAFUR5_13188 ATP-dependent DNA helicase hus2/rqh1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E CLAFUR5_13188 ATP-dependent DNA helicase hus2/rqh1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CLAFUR5_01323 DNA topoisomerase 3 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CLAFUR5_12629 RecQ-mediated genome instability protein 1 K15364 NCE4; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E CLAFUR5_09807 Replication factor A protein 1 K07466 RFA1; replication factor A1
E CLAFUR5_11041 Replication factor A protein 2 K10739 RFA2; replication factor A2
E CLAFUR5_02807 Replication factor A protein 3 K10740 RPA3; replication factor A3
D Protein phosphatase 4
E CLAFUR5_06360 uncharacterized protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E CLAFUR5_01613 Structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E CLAFUR5_12737 Structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E CLAFUR5_09977 Non-structural maintenance of chromosomes element 1 K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E CLAFUR5_00078 uncharacterized protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E CLAFUR5_05613 uncharacterized protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E CLAFUR5_00070 Putative 26S proteasome complex subunit sem-1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E CLAFUR5_07114 uncharacterized protein K10991 SWI5; DNA repair protein Swi5/Sae3
E CLAFUR5_12081 uncharacterized protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E CLAFUR5_07520 Structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E CLAFUR5_03057 uncharacterized protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E CLAFUR5_11672 Flap endonuclease GEN 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E CLAFUR5_13308 Flap endonuclease 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E CLAFUR5_01474 Chromatin modification-related protein eaf3 K11339 MORF4L1; mortality factor 4-like protein 1
E CLAFUR5_12843 uncharacterized protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E CLAFUR5_08427 DNA-dependent metalloprotease WSS1 K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
E CLAFUR5_08416 ATP-dependent DNA helicase mph1 K14635 MPH1; ATP-dependent DNA helicase MPH1 [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E CLAFUR5_05517 ATP-dependent DNA helicase II subunit 1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E CLAFUR5_01725 ATP-dependent DNA helicase II subunit 2 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E CLAFUR5_11193 Double-strand break repair protein mus-23 K10865 MRE11; double-strand break repair protein MRE11
E CLAFUR5_11902 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E CLAFUR5_03884 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E CLAFUR5_06928 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E CLAFUR5_06096 DNA polymerase type-X family protein pol4 K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
E CLAFUR5_01275 DNA polymerase lambda K10981 POL4; DNA polymerase IV [EC:2.7.7.7]
D Other NHEJ factors
E CLAFUR5_03493 Aprataxin-like protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E CLAFUR5_04662 uncharacterized protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E CLAFUR5_01360 uncharacterized protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
E CLAFUR5_00542 Centromere protein S K11511 APITD1; centromere protein S
D Bloom's syndrome complex (BTR)
E CLAFUR5_13188 ATP-dependent DNA helicase hus2/rqh1 K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E CLAFUR5_01323 DNA topoisomerase 3 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E CLAFUR5_12629 RecQ-mediated genome instability protein 1 K15364 NCE4; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
E CLAFUR5_08030 Fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E CLAFUR5_01236 DNA repair protein rhp51 K04482 RAD51; DNA repair protein RAD51
E CLAFUR5_08375 DNA replication checkpoint protein tel2 K11137 TELO2; telomere length regulation protein
E CLAFUR5_11458 UBP9-binding protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E CLAFUR5_10885 Guanine nucleotide-binding protein negative regulator 1 K23314 WRAP53; telomerase Cajal body protein 1
E CLAFUR5_06814 uncharacterized protein K24752 WDR70; WD repeat-containing protein 70
E CLAFUR5_09195 DNA damage-binding protein CMR1 K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D CLAFUR5_05940 N-acetyltransferase eso1 K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D CLAFUR5_00987 Triacylglycerol lipase ptl1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D CLAFUR5_00364 DNA polymerase kappa K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D CLAFUR5_09309 DNA repair protein rev1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D CLAFUR5_14519 DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D CLAFUR5_11829 Ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D CLAFUR5_11190 Postreplication repair E3 ubiquitin-protein ligase rad18 K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D CLAFUR5_02357 DNA repair protein RAD5 K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D CLAFUR5_01307 Helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CLAFUR5_01308 Putative matrix-associated actin-dependent regulator of chromatin K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D CLAFUR5_01123 Ubiquitin-conjugating enzyme variant MMS2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D CLAFUR5_01956 Ubiquitin-conjugating enzyme E2 35 K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D CLAFUR5_08152 Proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D CLAFUR5_13136 HMG box-containing protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D CLAFUR5_09974 DNA repair protein rad9 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D CLAFUR5_03387 Checkpoint protein hus1 K10903 HUS1; HUS1 checkpoint protein
D CLAFUR5_04327 DNA damage checkpoint control protein rad1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D CLAFUR5_00170 Cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D CLAFUR5_03647 Replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D CLAFUR5_07906 Replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D CLAFUR5_02060 Replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D CLAFUR5_06648 Replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D CLAFUR5_04327 DNA damage checkpoint control protein rad1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D CLAFUR5_10733 Topoisomerase 1-associated factor 1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D CLAFUR5_10498 Chromosome segregation in meiosis protein 3 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D CLAFUR5_04682 uncharacterized protein K11272 MRC1; mediator of replication checkpoint protein 1
C Triple T complex
D CLAFUR5_08375 DNA replication checkpoint protein tel2 K11137 TELO2; telomere length regulation protein
D CLAFUR5_06413 TEL2-interacting protein 1 K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D CLAFUR5_06843 uncharacterized protein K23388 UBL4; ubiquitin-like protein 4
D CLAFUR5_07142 Golgi to ER traffic protein 4 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D CLAFUR5_10583 uncharacterized protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D CLAFUR5_02993 Serine/threonine-protein kinase tel1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D CLAFUR5_13969 Serine/threonine-protein kinase chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D CLAFUR5_05096 putative serine/threonine-protein kinase FhkC K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D CLAFUR5_09112 M-phase inducer phosphatase K02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]
D CLAFUR5_04638 14-3-3 family protein ArtA K06630 YWHAE; 14-3-3 protein epsilon
D CLAFUR5_04944 uncharacterized protein K06630 YWHAE; 14-3-3 protein epsilon
D CLAFUR5_09402 Mitosis inhibitor protein kinase wee1 K03114 SWE1; mitosis inhibitor protein kinase SWE1 [EC:2.7.11.1]
D CLAFUR5_02274 Fork head 1 K24664 FKH; forkhead protein FKH
D CLAFUR5_13353 Vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
D CLAFUR5_01648 Telomere maintenance protein SDE2 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D CLAFUR5_09111 rDNA transcriptional regulator pol5 K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D CLAFUR5_00574 DNA cross-link repair 1A protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D CLAFUR5_09651 Exonuclease V K17815 EXO5; exonuclease V [EC:3.1.-.-]
D CLAFUR5_04486 Nuclease S1 K05986 NUCS; nuclease S1 [EC:3.1.30.1]
D CLAFUR5_12927 Nuclease S1 K05986 NUCS; nuclease S1 [EC:3.1.30.1]
C Helicases
D CLAFUR5_04113 DNA excision repair protein ERCC-6-like 2 K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D CLAFUR5_11233 Pre-mRNA-splicing factor cef1 K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D CLAFUR5_11937 Pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D CLAFUR5_01635 Pre-mRNA-splicing factor prp46 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D CLAFUR5_03758 uncharacterized protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAFUR5_12437 Nudix hydrolase 1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAFUR5_08004 putative deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CLAFUR5_13557 putative deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CLAFUR5_13777 Ribonucleoside-diphosphate reductase large chain K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D CLAFUR5_03274 Ribonucleoside-diphosphate reductase small chain K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D CLAFUR5_07556 uncharacterized protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D CLAFUR5_04668 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D CLAFUR5_14317 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E CLAFUR5_12688 Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E CLAFUR5_13684 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E CLAFUR5_00181 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E CLAFUR5_00411 ATP-dependent DNA helicase srs2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E CLAFUR5_00411 ATP-dependent DNA helicase srs2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D CLAFUR5_03758 uncharacterized protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAFUR5_12437 Nudix hydrolase 1 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D CLAFUR5_08004 putative deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D CLAFUR5_13557 putative deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024