+D Protein KO
#
Membrane Trafficking - Fomitiporia mediterranea
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
D FOMMEDRAFT_154625 hypothetical protein K28063 ESYT; extended synaptotagmin
D FOMMEDRAFT_19642 tricalbin K28063 ESYT; extended synaptotagmin
C Septins
D FOMMEDRAFT_140075 cell division control/GTP binding protein K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D FOMMEDRAFT_123385 kinase-like protein K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D FOMMEDRAFT_124022 PLC-like phosphodiesterase K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
D FOMMEDRAFT_142749 phospholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D FOMMEDRAFT_97626 phospholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D FOMMEDRAFT_98391 SAICAR synthase-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D FOMMEDRAFT_128967 Pkinase-domain-containing protein K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D FOMMEDRAFT_142113 Pkinase-domain-containing protein K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D FOMMEDRAFT_85951 Pkinase-domain-containing protein K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D FOMMEDRAFT_139224 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D FOMMEDRAFT_112973 Pkinase-domain-containing protein K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D FOMMEDRAFT_88295 EF-hand K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D FOMMEDRAFT_107155 GTP-binding protein SAS1 K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D FOMMEDRAFT_131228 calmodulin-A K02183 CALM; calmodulin
D FOMMEDRAFT_29313 myosin regulatory light chain cdc4 K02183 CALM; calmodulin
D FOMMEDRAFT_23207 hypothetical protein K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D FOMMEDRAFT_115452 Sec1-like protein K15292 STXBP1; syntaxin-binding protein 1
D FOMMEDRAFT_166920 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
D FOMMEDRAFT_22059 DNase I-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D FOMMEDRAFT_115702 TBC-domain-containing protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D FOMMEDRAFT_134232 TPR-like protein K13342 PEX5; peroxin-5
D FOMMEDRAFT_85296 TPR-like protein K13342 PEX5; peroxin-5
D FOMMEDRAFT_90072 FAD/NAD-binding domain-containing protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D FOMMEDRAFT_145173 rab-protein geranylgeranyltransferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D FOMMEDRAFT_128159 terpenoid cyclases/Protein prenyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D FOMMEDRAFT_170459 terpenoid cyclases/Protein prenyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D FOMMEDRAFT_106015 hypothetical protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D FOMMEDRAFT_26993 small GTPase Cdc42 K04393 CDC42; cell division control protein 42
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D FOMMEDRAFT_82797 hypothetical protein K19983 EXOC1; exocyst complex component 1
D FOMMEDRAFT_152861 hypothetical protein K17637 EXOC2; exocyst complex component 2
D FOMMEDRAFT_137669 exocyst complex component Sec6 K06110 EXOC3; exocyst complex component 3
D FOMMEDRAFT_111516 exocyst complex protein K19984 EXOC5; exocyst complex component 5
D FOMMEDRAFT_135388 exocyst complex component, sec15 subunit K19985 EXOC6; exocyst complex component 6
D FOMMEDRAFT_18097 hypothetical protein K07195 EXOC7; exocyst complex component 7
D FOMMEDRAFT_23599 hypothetical protein K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D FOMMEDRAFT_17446 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D FOMMEDRAFT_24741 hypothetical protein K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D FOMMEDRAFT_135863 hypothetical protein K19877 CHS5; chitin biosynthesis protein CHS5
D FOMMEDRAFT_103596 chaps-domain-containing protein K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D FOMMEDRAFT_168848 hypothetical protein K12481 RBSN; rabenosyn-5
D FOMMEDRAFT_109644 scamp-domain-containing protein K19995 SCAMP; secretory carrier-associated membrane protein
D FOMMEDRAFT_143979 CRAL/TRIO domain-containing protein K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D FOMMEDRAFT_119156 t-SNARE K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D FOMMEDRAFT_107983 t-SNARE K08489 STX16; syntaxin 16
C Stx-cisGolgi
D FOMMEDRAFT_120827 integral membrane protein sed5 K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
D FOMMEDRAFT_126341 hypothetical protein K08492 STX18; syntaxin 18
B SNAP-25[N] (Qb)
C Vti1
D FOMMEDRAFT_19834 vesicle transport v-snare protein vti1 K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D FOMMEDRAFT_105633 v-SNARE protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D FOMMEDRAFT_108042 golgi SNAP receptor complex member bos1 K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
D FOMMEDRAFT_113253 Sec20-domain-containing protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
C STX8
D FOMMEDRAFT_130934 hypothetical protein K08501 STX8; syntaxin 8
D FOMMEDRAFT_133388 syntaxin K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D FOMMEDRAFT_155443 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D FOMMEDRAFT_106221 synaptosome-associated proteinsynaptosomal-associated protein 25 K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D FOMMEDRAFT_101864 synaptobrevin K08513 VAMP4; vesicle-associated membrane protein 4
D FOMMEDRAFT_25062 VAMP/synaptobrevin-like protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D FOMMEDRAFT_101900 vesicle membrane protein with acyltransferase activity K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D FOMMEDRAFT_21347 protein transport protein Sec22 K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D FOMMEDRAFT_166920 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D FOMMEDRAFT_115452 Sec1-like protein K15292 STXBP1; syntaxin-binding protein 1
D FOMMEDRAFT_106423 Sly1 vesicle trafficking sec1-like protein K19998 SCFD1; sec1 family domain-containing protein 1
C Palmitoyltransferases
D FOMMEDRAFT_114357 zf-DHHC-domain-containing protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
C Others
D FOMMEDRAFT_88907 AAA-domain-containing protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D FOMMEDRAFT_121611 vesicular-fusion protein SEC17 K15296 NAPA; alpha-soluble NSF attachment protein
D FOMMEDRAFT_82758 lipid binding protein K17919 SNX4; sorting nexin-4
D FOMMEDRAFT_115887 hypothetical protein K21996 SNX41_42; sorting nexin-41/42
D FOMMEDRAFT_23020 GPP34-domain-containing protein K15620 GOLPH3; golgi phosphoprotein 3
D FOMMEDRAFT_164470 AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D FOMMEDRAFT_22319 hypothetical protein K14012 NSFL1C; UBX domain-containing protein 1
D FOMMEDRAFT_50534 SEP-domain-containing protein K14012 NSFL1C; UBX domain-containing protein 1
D FOMMEDRAFT_171056 hypothetical protein K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D FOMMEDRAFT_115867 clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D FOMMEDRAFT_112306 dynamin protein dnm1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D FOMMEDRAFT_83249 Adaptor protein complex AP-2 alpha subunit K11824 AP2A; AP-2 complex subunit alpha
D FOMMEDRAFT_104422 Adaptor protein complex beta subunit K11825 AP2B1; AP-2 complex subunit beta-1
D FOMMEDRAFT_88067 clathrin adaptor, mu subunit K11826 AP2M1; AP-2 complex subunit mu-1
D FOMMEDRAFT_169601 clathrin coat assembly protein ap17 K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D FOMMEDRAFT_91102 ENTH-domain-containing protein K12471 EPN; epsin
D FOMMEDRAFT_124323 hypothetical protein K12472 EPS15; epidermal growth factor receptor substrate 15
D FOMMEDRAFT_150228 ANTH-domain-containing protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D FOMMEDRAFT_122221 BAR-domain-containing protein K12562 AMPH; amphiphysin
D FOMMEDRAFT_149578 hypothetical protein K17923 SNX9_18_33; sorting nexin-9/18/33
D FOMMEDRAFT_141675 hypothetical protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D FOMMEDRAFT_145486 hypothetical protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D FOMMEDRAFT_124771 heat shock protein HSS1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D FOMMEDRAFT_18191 heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D FOMMEDRAFT_98391 SAICAR synthase-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D FOMMEDRAFT_131011 hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D FOMMEDRAFT_85186 hypothetical protein K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D FOMMEDRAFT_22059 DNase I-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D FOMMEDRAFT_148036 inositol polyphosphate phosphatase K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D FOMMEDRAFT_128984 hypothetical protein K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D FOMMEDRAFT_78450 kinase-like protein K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D FOMMEDRAFT_117411 HECT-domain-containing protein K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D FOMMEDRAFT_145882 hypothetical protein K20040 HIP1R; huntingtin-interacting protein 1-related protein
D FOMMEDRAFT_96000 Calreticulin-domain-containing protein K08054 CANX; calnexin
D FOMMEDRAFT_20978 adaptin ear-binding coat-associated protein 1 NECAP-1 K20069 NECAP1_2; adaptin ear-binding coat-associated protein 1/2
D FOMMEDRAFT_129070 zf-DHHC-domain-containing protein K20031 ZDHHC6; palmitoyltransferase ZDHHC6 [EC:2.3.1.225]
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D FOMMEDRAFT_112306 dynamin protein dnm1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D FOMMEDRAFT_171362 hypothetical protein K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
C GRAF1-dependent endocytosis
D FOMMEDRAFT_26993 small GTPase Cdc42 K04393 CDC42; cell division control protein 42
D FOMMEDRAFT_29893 ARF/SAR K07937 ARF1_2; ADP-ribosylation factor 1/2
C Arf6-dependent endocytosis
D FOMMEDRAFT_168107 CPS1 protein K07941 ARF6; ADP-ribosylation factor 6
C RhoA-dependent endocytosis
D FOMMEDRAFT_96248 small GTPase-binding protein K04513 RHOA; Ras homolog gene family, member A
D FOMMEDRAFT_112306 dynamin protein dnm1 K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D FOMMEDRAFT_106001 hypothetical protein K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D FOMMEDRAFT_102614 ras protein K07827 KRAS; GTPase KRas
D FOMMEDRAFT_106970 ras protein K07827 KRAS; GTPase KRas
D FOMMEDRAFT_158201 ras-1 K07827 KRAS; GTPase KRas
D FOMMEDRAFT_26993 small GTPase Cdc42 K04393 CDC42; cell division control protein 42
C Kinases
D FOMMEDRAFT_138537 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D FOMMEDRAFT_105874 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
C Phospholipase C
D FOMMEDRAFT_124022 PLC-like phosphodiesterase K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
C Sorting nexins
D FOMMEDRAFT_101108 hypothetical protein K17917 SNX1_2; sorting nexin-1/2
D FOMMEDRAFT_149578 hypothetical protein K17923 SNX9_18_33; sorting nexin-9/18/33
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D FOMMEDRAFT_122221 BAR-domain-containing protein K12562 AMPH; amphiphysin
D FOMMEDRAFT_122666 BAR-domain-containing protein K20120 BIN3; bridging integrator 3
C F-BAR proteins
D FOMMEDRAFT_114603 hypothetical protein K20121 FNBP1; formin-binding protein 1
D FOMMEDRAFT_100931 RhoGAP-domain-containing protein K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D FOMMEDRAFT_143148 ras-domain-containing protein K07888 RAB5B; Ras-related protein Rab-5B
C Rab associated proteins
D FOMMEDRAFT_144395 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D FOMMEDRAFT_168848 hypothetical protein K12481 RBSN; rabenosyn-5
D FOMMEDRAFT_22059 DNase I-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D FOMMEDRAFT_138537 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D FOMMEDRAFT_123012 hypothetical protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D FOMMEDRAFT_97667 vacuolar protein sorting-associated protein 45 K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D FOMMEDRAFT_29893 ARF/SAR K07937 ARF1_2; ADP-ribosylation factor 1/2
D FOMMEDRAFT_168107 CPS1 protein K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D FOMMEDRAFT_165785 ArfGap-domain-containing protein K12486 SMAP; stromal membrane-associated protein
D FOMMEDRAFT_133996 hypothetical protein K12494 PSD; PH and SEC7 domain-containing protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D FOMMEDRAFT_134792 hypothetical protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D FOMMEDRAFT_30102 hypothetical protein K21842 EFR3; protein EFR3
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D FOMMEDRAFT_143148 ras-domain-containing protein K07888 RAB5B; Ras-related protein Rab-5B
D FOMMEDRAFT_122462 ras-domain-containing protein K07897 RAB7A; Ras-related protein Rab-7A
D FOMMEDRAFT_19344 hypothetical protein K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D FOMMEDRAFT_19740 vacuolar protein sorting-associated protein 35 K18468 VPS35; vacuolar protein sorting-associated protein 35
D FOMMEDRAFT_144988 Metallo-dependent phosphatase K18467 VPS29; vacuolar protein sorting-associated protein 29
D FOMMEDRAFT_168445 vacuolar protein sorting-associated protein 26 K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D FOMMEDRAFT_141270 HOOK-domain-containing protein K16536 HOOK3; protein HOOK3
C FERRY complex
C Rab associated proteins
D FOMMEDRAFT_133178 hypothetical protein K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D FOMMEDRAFT_138537 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D FOMMEDRAFT_17969 N-terminal nucleophile aminohydrolase K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D FOMMEDRAFT_104560 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D FOMMEDRAFT_124804 RabGAP/TBC K20168 TBC1D15; TBC1 domain family member 15
D FOMMEDRAFT_90072 FAD/NAD-binding domain-containing protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D FOMMEDRAFT_145173 rab-protein geranylgeranyltransferase K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D FOMMEDRAFT_128159 terpenoid cyclases/Protein prenyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D FOMMEDRAFT_170459 terpenoid cyclases/Protein prenyltransferase K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D FOMMEDRAFT_102375 TBC-domain-containing protein K20176 SGSM3; small G protein signaling modulator 3
D FOMMEDRAFT_23020 GPP34-domain-containing protein K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D FOMMEDRAFT_114506 Arl8a protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D FOMMEDRAFT_104889 acyl-CoA N-acyltransferase K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D FOMMEDRAFT_166473 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D FOMMEDRAFT_165802 hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D FOMMEDRAFT_107311 ubiquitin binding protein K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D FOMMEDRAFT_74561 hypothetical protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D FOMMEDRAFT_153369 UEV-domain-containing protein K12183 TSG101; ESCRT-I complex subunit TSG101
D FOMMEDRAFT_159986 VPS28-domain-containing protein K12184 VPS28; ESCRT-I complex subunit VPS28
D FOMMEDRAFT_93414 VPS28-domain-containing protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D FOMMEDRAFT_170739 winged helix DNA-binding domain-containing protein K12188 SNF8; ESCRT-II complex subunit VPS22
D FOMMEDRAFT_137803 ESCRT-II complex, vps25 subunit K12189 VPS25; ESCRT-II complex subunit VPS25
D FOMMEDRAFT_105283 hypothetical protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D FOMMEDRAFT_21931 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D FOMMEDRAFT_145117 vacuolar sorting protein DID4 K12191 CHMP2A; charged multivesicular body protein 2A
D FOMMEDRAFT_89532 vacuolar sorting protein Vps24 K12193 VPS24; charged multivesicular body protein 3
D FOMMEDRAFT_158374 hypothetical protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D FOMMEDRAFT_21472 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D FOMMEDRAFT_167148 hypothetical protein K12195 CHMP6; charged multivesicular body protein 6
D FOMMEDRAFT_109799 Snf7-domain-containing protein K15053 CHMP7; charged multivesicular body protein 7
D FOMMEDRAFT_19504 AAA-domain-containing protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D FOMMEDRAFT_167300 DUF605-domain-containing protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D FOMMEDRAFT_144555 BRO1-domain-containing protein K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D FOMMEDRAFT_162532 hypothetical protein K20177 VPS3; vacuolar protein sorting-associated protein 3
D FOMMEDRAFT_85939 lateendosome to vacuole transport-family protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D FOMMEDRAFT_20927 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D FOMMEDRAFT_94513 vacuolar protein sorting-associated protein 16 K20180 VPS16; vacuolar protein sorting-associated protein 16
D FOMMEDRAFT_133407 DigA protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D FOMMEDRAFT_167077 Sec1-like protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D FOMMEDRAFT_20927 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D FOMMEDRAFT_94513 vacuolar protein sorting-associated protein 16 K20180 VPS16; vacuolar protein sorting-associated protein 16
D FOMMEDRAFT_133407 DigA protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D FOMMEDRAFT_167077 Sec1-like protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D FOMMEDRAFT_117970 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D FOMMEDRAFT_22080 vacuolar assembling protein VPS41 K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D FOMMEDRAFT_106015 hypothetical protein K24155 DMXL; rabconnectin-3a
D FOMMEDRAFT_23709 WD40 repeat-like protein K24738 WDR7; rabconnectin-3b
C RAVE complex
D FOMMEDRAFT_106015 hypothetical protein K24155 DMXL; rabconnectin-3a
D FOMMEDRAFT_26674 ubiquitin-protein ligase K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D FOMMEDRAFT_95562 Adaptor protein complex AP-3 delta subunit K12396 AP3D; AP-3 complex subunit delta
D FOMMEDRAFT_131430 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D FOMMEDRAFT_126082 clathrin adaptor, mu subunit K12398 AP3M; AP-3 complex subunit mu
D FOMMEDRAFT_106994 Adaptor protein complex sigma subunit K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Lysosomal membrane proteins
C Others
D FOMMEDRAFT_94969 DUF254-domain-containing protein K20195 MON1; vacuolar fusion protein MON1
D FOMMEDRAFT_170050 cysteine proteinase K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D FOMMEDRAFT_75427 Mov34/MPN/PAD-1 K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D FOMMEDRAFT_86688 Mov34-domain-containing protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D FOMMEDRAFT_132448 vacuolar protein sorting 55 K28212 LEPROT; OB-RGRP/VPS55 family protein
D FOMMEDRAFT_18306 hypothetical protein K23481 VPS1; vacuolar protein sorting-associated protein 1
D FOMMEDRAFT_82576 SPRY-domain-containing protein K28544 SSH4; SSH4 family protein
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D FOMMEDRAFT_19409 ras-domain-containing protein K07880 RAB4B; Ras-related protein Rab-4B
C Rab4 associated proteins
D FOMMEDRAFT_168848 hypothetical protein K12481 RBSN; rabenosyn-5
D FOMMEDRAFT_82758 lipid binding protein K17919 SNX4; sorting nexin-4
D FOMMEDRAFT_126556 hypothetical protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D FOMMEDRAFT_30574 WD40 repeat-like protein K14004 SEC13; protein transport protein SEC13
D FOMMEDRAFT_135388 exocyst complex component, sec15 subunit K19985 EXOC6; exocyst complex component 6
D FOMMEDRAFT_84895 RabGAP/TBC K20242 EVI5; ecotropic viral integration site 5 protein
D FOMMEDRAFT_133514 RabGAP/TBC K20167 TBC1D14; TBC1 domain family member 14
D FOMMEDRAFT_23020 GPP34-domain-containing protein K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D FOMMEDRAFT_22059 DNase I-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D FOMMEDRAFT_144395 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D FOMMEDRAFT_102949 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D FOMMEDRAFT_111191 Vps52-domain-containing protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D FOMMEDRAFT_108090 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D FOMMEDRAFT_129814 F-actin capping protein, alpha subunit K10364 CAPZA; F-actin-capping protein subunit alpha
D FOMMEDRAFT_117353 F-actin capping protein, beta subunit K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
D FOMMEDRAFT_144988 Metallo-dependent phosphatase K18467 VPS29; vacuolar protein sorting-associated protein 29
C Others
D FOMMEDRAFT_146573 hypothetical protein K24964 BLTP1; Bridge-like lipid transfer protein family member 1
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D FOMMEDRAFT_23020 GPP34-domain-containing protein K15620 GOLPH3; golgi phosphoprotein 3
D FOMMEDRAFT_167584 kinesin-domain-containing protein K10402 KIF20; kinesin family member 20
D FOMMEDRAFT_115702 TBC-domain-containing protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D FOMMEDRAFT_132793 galactose oxidase K20285 RABEPK; Rab9 effector protein with kelch motifs
D FOMMEDRAFT_83288 dynactin K04648 DCTN1; dynactin 1
D FOMMEDRAFT_22059 DNase I-like protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D FOMMEDRAFT_133320 vacuolar protein sorting-associated protein vps13 K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D FOMMEDRAFT_29893 ARF/SAR K07937 ARF1_2; ADP-ribosylation factor 1/2
D FOMMEDRAFT_135304 ARF/SAR K07942 ARL1; ADP-ribosylation factor-like protein 1
D FOMMEDRAFT_167968 P-loop containing nucleoside triphosphate hydrolase protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D FOMMEDRAFT_126649 ArfGap-domain-containing protein K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D FOMMEDRAFT_114090 ArfGap-domain-containing protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D FOMMEDRAFT_165785 ArfGap-domain-containing protein K12486 SMAP; stromal membrane-associated protein
D FOMMEDRAFT_88337 Sec7-domain-containing protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D FOMMEDRAFT_145161 Sec7-domain-containing protein K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D FOMMEDRAFT_145857 hypothetical protein K20288 COG1; conserved oligomeric Golgi complex subunit 1
D FOMMEDRAFT_140733 COG complex component K20289 COG2; conserved oligomeric Golgi complex subunit 2
D FOMMEDRAFT_107953 Sec34-domain-containing protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D FOMMEDRAFT_103809 COG4-domain-containing protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D FOMMEDRAFT_146834 hypothetical protein K20292 COG5; conserved oligomeric Golgi complex subunit 5
D FOMMEDRAFT_79627 oligomeric complex COG6 K20293 COG6; conserved oligomeric Golgi complex subunit 6
D FOMMEDRAFT_114459 hypothetical protein K20294 COG7; conserved oligomeric Golgi complex subunit 7
D FOMMEDRAFT_154557 Dor1-domain-containing protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D FOMMEDRAFT_102949 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D FOMMEDRAFT_111191 Vps52-domain-containing protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D FOMMEDRAFT_108090 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D FOMMEDRAFT_26558 Vps54-domain-containing protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D FOMMEDRAFT_167891 TRAPP complex subunit bet5 K20300 TRAPPC1; trafficking protein particle complex subunit 1
D FOMMEDRAFT_125407 Sedlin K20301 TRAPPC2; trafficking protein particle complex subunit 2
D FOMMEDRAFT_125678 transport protein particle complex subunit K20301 TRAPPC2; trafficking protein particle complex subunit 2
D FOMMEDRAFT_124908 transport protein particle complex subunit K20302 TRAPPC3; trafficking protein particle complex subunit 3
D FOMMEDRAFT_124513 TRAPP complex subunit Trs23 K20303 TRAPPC4; trafficking protein particle complex subunit 4
D FOMMEDRAFT_140377 TRAPP complex subunit trs31 K20280 TRAPPC5; trafficking protein particle complex subunit 5
D FOMMEDRAFT_122410 transport protein particle component K20304 TRAPPC6; trafficking protein particle complex subunit 6
D FOMMEDRAFT_106503 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D FOMMEDRAFT_104469 Trs120-domain-containing protein K20306 TRAPPC9; trafficking protein particle complex subunit 9
D FOMMEDRAFT_79224 hypothetical protein K20307 TRAPPC10; trafficking protein particle complex subunit 10
D FOMMEDRAFT_138064 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D FOMMEDRAFT_137814 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D FOMMEDRAFT_157307 DUF974-domain-containing protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D FOMMEDRAFT_100643 Adaptor protein complex AP-1 gamma subunit K12391 AP1G1; AP-1 complex subunit gamma-1
D FOMMEDRAFT_145580 Adaptor protein complex beta subunit K12392 AP1B1; AP-1 complex subunit beta-1
D FOMMEDRAFT_20772 clathrin adaptor, mu subunit K12393 AP1M; AP-1 complex subunit mu
D FOMMEDRAFT_89784 Adaptor protein complex sigma subunit K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D FOMMEDRAFT_95562 Adaptor protein complex AP-3 delta subunit K12396 AP3D; AP-3 complex subunit delta
D FOMMEDRAFT_131430 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D FOMMEDRAFT_126082 clathrin adaptor, mu subunit K12398 AP3M; AP-3 complex subunit mu
D FOMMEDRAFT_106994 Adaptor protein complex sigma subunit K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D FOMMEDRAFT_71660 VHS-domain-containing protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D FOMMEDRAFT_145569 clathrin-coated vesicle protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D FOMMEDRAFT_142749 phospholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D FOMMEDRAFT_97626 phospholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D FOMMEDRAFT_134792 hypothetical protein K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D FOMMEDRAFT_98391 SAICAR synthase-like protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D FOMMEDRAFT_105874 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D FOMMEDRAFT_112301 hypothetical protein K20318 SYS1; protein SYS1
D FOMMEDRAFT_98389 vacuole protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D FOMMEDRAFT_117622 TMS membrane protein/tumor differentially expressed protein K23544 SERINC1; serine incorporator 1
D FOMMEDRAFT_85303 Phox-like protein K17918 SNX3_12; sorting nexin-3/12
D FOMMEDRAFT_143983 hypothetical protein K17922 SNX8; sorting nexin-8
D FOMMEDRAFT_142756 hypothetical protein K26678 MON2; protein MON2
D FOMMEDRAFT_170958 hypothetical protein K26680 DOP1; protein dopey
D FOMMEDRAFT_20875 hypothetical protein K27894 HID1; protein HID1
D FOMMEDRAFT_106469 Golgi apparatus membrane protein TVP23 K26752 TVP23; golgi apparatus membrane protein TVP23
D FOMMEDRAFT_117170 hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D FOMMEDRAFT_169552 Golgi apparatus membrane protein TVP38 K26753 TVP38; golgi apparatus membrane protein TVP38
D FOMMEDRAFT_18306 hypothetical protein K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D FOMMEDRAFT_141443 ARF/SAR K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D FOMMEDRAFT_30574 WD40 repeat-like protein K14004 SEC13; protein transport protein SEC13
D FOMMEDRAFT_138994 WD40 repeat-like protein K14005 SEC31; protein transport protein SEC31
D FOMMEDRAFT_130391 copii coat protein K14006 SEC23; protein transport protein SEC23
D FOMMEDRAFT_113318 CPII coat sec24 protein K14007 SEC24; protein transport protein SEC24
D FOMMEDRAFT_113703 hypothetical protein K14007 SEC24; protein transport protein SEC24
D FOMMEDRAFT_158342 WD40 repeat-like protein K14003 PREB; prolactin regulatory element-binding protein
D FOMMEDRAFT_139329 hypothetical protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D FOMMEDRAFT_167891 TRAPP complex subunit bet5 K20300 TRAPPC1; trafficking protein particle complex subunit 1
D FOMMEDRAFT_125407 Sedlin K20301 TRAPPC2; trafficking protein particle complex subunit 2
D FOMMEDRAFT_125678 transport protein particle complex subunit K20301 TRAPPC2; trafficking protein particle complex subunit 2
D FOMMEDRAFT_124908 transport protein particle complex subunit K20302 TRAPPC3; trafficking protein particle complex subunit 3
D FOMMEDRAFT_124513 TRAPP complex subunit Trs23 K20303 TRAPPC4; trafficking protein particle complex subunit 4
D FOMMEDRAFT_140377 TRAPP complex subunit trs31 K20280 TRAPPC5; trafficking protein particle complex subunit 5
D FOMMEDRAFT_122410 transport protein particle component K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D FOMMEDRAFT_158326 supernatant protein factor C-terminal domain-containing protein K20347 TMED2; p24 family protein beta-1
C PDI family proteins
D FOMMEDRAFT_169574 thioredoxin-domain-containing protein K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D FOMMEDRAFT_89124 protein disulfide isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D FOMMEDRAFT_112230 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D FOMMEDRAFT_138554 protein disulfide isomerase K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D FOMMEDRAFT_18002 GTP-binding protein ypt1 K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
D FOMMEDRAFT_20086 ER to Golgi transport-related protein K20359 RABAC1; PRA1 family protein 1
D FOMMEDRAFT_170559 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D FOMMEDRAFT_123289 RabGAP/TBC K20360 TBC1D22; TBC1 domain family member 2
D FOMMEDRAFT_107994 protein transporter yif1 K20362 YIF1; protein transport protein YIF1
D FOMMEDRAFT_88518 Yos1-like protein K22939 IER3IP1; immediate early response 3-interacting protein 1
D FOMMEDRAFT_101773 hypothetical protein K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D FOMMEDRAFT_164846 hypothetical protein K10082 LMAN2; lectin, mannose-binding 2
D FOMMEDRAFT_136669 seven-hairpin glycosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D FOMMEDRAFT_149844 seven-hairpin glycosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D FOMMEDRAFT_143158 glycoside hydrolase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D FOMMEDRAFT_17283 DUF1692-domain-containing protein K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D FOMMEDRAFT_143544 endoplasmic reticulum-derived transport vesicle ERV46 K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D FOMMEDRAFT_116822 cornichon K20368 CNIH; protein cornichon
D FOMMEDRAFT_17775 SURF4-domain-containing protein K20369 ERV29; ER-derived vesicles protein
D FOMMEDRAFT_166523 heat shock protein 70 K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D FOMMEDRAFT_170806 chaperone protein BipA K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D FOMMEDRAFT_128332 coatomer subunit alpha-2 K05236 COPA; coatomer subunit alpha
D FOMMEDRAFT_128909 coatomer protein K17301 COPB1; coatomer subunit beta
D FOMMEDRAFT_30346 coatomer protein K17302 COPB2; coatomer subunit beta'
D FOMMEDRAFT_120967 coatomer subunit gamma K17267 COPG; coatomer subunit gamma
D FOMMEDRAFT_82189 hypothetical protein K20471 COPD; coatomer subunit delta
D FOMMEDRAFT_73853 hypothetical protein K17268 COPE; coatomer subunit epsilon
D FOMMEDRAFT_16644 coatomer protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D FOMMEDRAFT_167339 Sec39-domain-containing protein K20473 NBAS; neuroblastoma-amplified sequence
D FOMMEDRAFT_167449 hypothetical protein K20474 RINT1; RAD50-interacting protein 1
D FOMMEDRAFT_115831 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
C Golgi to ER traffic proteins (GET)
D FOMMEDRAFT_156408 hypothetical protein K22384 GET1; tail-anchored protein insertion receptor
D FOMMEDRAFT_155641 hypothetical protein K22386 GET2; GET complex subunit GET2
D FOMMEDRAFT_107218 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D FOMMEDRAFT_77375 cytoplasmic protein K23387 GET4; golgi to ER traffic protein 4
D FOMMEDRAFT_98302 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
C Rab GTPases
C Rab associated proteins
D FOMMEDRAFT_106856 RIC1-domain-containing protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D FOMMEDRAFT_146445 Rgp1-domain-containing protein K20477 RGP1; RAB6A-GEF complex partner protein 2
D FOMMEDRAFT_150785 ER lumen protein retaining receptor K10949 KDELR; ER lumen protein retaining receptor
D FOMMEDRAFT_168848 hypothetical protein K12481 RBSN; rabenosyn-5
D FOMMEDRAFT_123289 RabGAP/TBC K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D FOMMEDRAFT_167188 hypothetical protein K20456 OSBP; oxysterol-binding protein 1
D FOMMEDRAFT_121479 hypothetical protein K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D FOMMEDRAFT_167663 oxysterol-binding protein family K22285 OSBPL8; oxysterol-binding protein-related protein 8
D FOMMEDRAFT_120223 Oxysterol-binding protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D FOMMEDRAFT_146816 hypothetical protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D FOMMEDRAFT_141115 Yip1 domain family protein K22940 YIPF1_2; protein YIPF1/2
D FOMMEDRAFT_84798 Yip1-domain-containing protein K20363 YIPF5_7; protein YIPF5/7
D FOMMEDRAFT_102821 Yip1-domain-containing protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D FOMMEDRAFT_105424 DUF1620-domain-containing protein K23562 EMC1; ER membrane protein complex subunit 1
D FOMMEDRAFT_103279 TPR-like protein K23563 EMC2; ER membrane protein complex subunit 2
D FOMMEDRAFT_110811 transmembrane protein K23564 EMC3; ER membrane protein complex subunit 3
D FOMMEDRAFT_166505 endoplasmic reticulum protein K23565 EMC4; ER membrane protein complex subunit 4
D FOMMEDRAFT_73630 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D FOMMEDRAFT_142240 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D FOMMEDRAFT_81026 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
D FOMMEDRAFT_66242 UPF0172-domain-containing protein K23569 EMC8_9; ER membrane protein complex subunit 8/9
D FOMMEDRAFT_147942 hypothetical protein K23570 EMC10; ER membrane protein complex subunit 10
C SEC61 complex
D FOMMEDRAFT_124084 SecY protein K10956 SEC61A; protein transport protein SEC61 subunit alpha
D FOMMEDRAFT_116220 Pre protein translocase Sec Sec61-beta subunit K09481 SEC61B; protein transport protein SEC61 subunit beta
D FOMMEDRAFT_113874 secE/sec61-gamma protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D FOMMEDRAFT_110762 DUF1682-domain-containing protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D FOMMEDRAFT_125597 PGAP1-domain-containing protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D FOMMEDRAFT_139440 Per1-like protein K23553 PGAP3; post-GPI attachment to proteins factor 3
D FOMMEDRAFT_156561 Metallo-dependent phosphatase K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D FOMMEDRAFT_20254 Metallo-dependent phosphatase K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D FOMMEDRAFT_106423 Sly1 vesicle trafficking sec1-like protein K19998 SCFD1; sec1 family domain-containing protein 1
D FOMMEDRAFT_28052 hypothetical protein K20724 TMEM33; transmembrane protein 33
D FOMMEDRAFT_167388 hypothetical protein K23554 GRAMD4; GRAM domain-containing protein 4
D FOMMEDRAFT_149324 VAMP-associated protein K06096 VAPA; vesicle-associated membrane protein-associated protein A
D FOMMEDRAFT_131589 Arv1-domain-containing protein K21848 ARV1; lipid intermediate transporter
D FOMMEDRAFT_156347 hypothetical protein K21848 ARV1; lipid intermediate transporter
D FOMMEDRAFT_128778 beta-glucan synthesis-associated protein K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D FOMMEDRAFT_169152 beta-glucan synthesis-associated K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D FOMMEDRAFT_21392 beta-glucan synthesis-associated K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D FOMMEDRAFT_25073 beta-glucan synthesis-associated K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D FOMMEDRAFT_90323 glycoside hydrolase family 16 protein K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D FOMMEDRAFT_97318 glycoside hydrolase family 16 protein K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D FOMMEDRAFT_23020 GPP34-domain-containing protein K15620 GOLPH3; golgi phosphoprotein 3
D FOMMEDRAFT_170500 hypothetical protein K23292 LNPK; endoplasmic reticulum junction formation protein lunapark
D FOMMEDRAFT_107724 Got1-domain-containing protein K26683 GOLT1; vesicle transport protein GOT1
D FOMMEDRAFT_20195 root hair defective 3 GTP-binding protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D FOMMEDRAFT_144283 hypothetical protein K21357 ULK1; serine/threonine-protein kinase ULK1 [EC:2.7.11.1]
D FOMMEDRAFT_130907 hypothetical protein K08331 ATG13; autophagy-related protein 13
D FOMMEDRAFT_170826 DUF1649-domain-containing protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D FOMMEDRAFT_108769 kinase-like protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D FOMMEDRAFT_130907 hypothetical protein K08331 ATG13; autophagy-related protein 13
D FOMMEDRAFT_165630 hypothetical protein K08329 ATG17; autophagy-related protein 17
C PI3K complex
D FOMMEDRAFT_138537 phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D FOMMEDRAFT_123012 hypothetical protein K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D FOMMEDRAFT_140741 APG6-domain-containing protein K08334 BECN; beclin
C ATG9 transmembrane protein
D FOMMEDRAFT_26570 APG9-domain-containing protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D FOMMEDRAFT_118735 WD40 repeat-like protein K17908 WIPI1_2; autophagy-related protein 18
D FOMMEDRAFT_153115 hypothetical protein K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D FOMMEDRAFT_71712 APG12-domain-containing protein K08336 ATG12; ubiquitin-like protein ATG12
D FOMMEDRAFT_109016 ubiquitin-like conjugating enzyme K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D FOMMEDRAFT_169476 hypothetical protein K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D FOMMEDRAFT_107692 autophagy protein 5 K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D FOMMEDRAFT_109229 symbiosis-related protein K08341 GABARAP; GABA(A) receptor-associated protein
D FOMMEDRAFT_133827 hypothetical protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D FOMMEDRAFT_109016 ubiquitin-like conjugating enzyme K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D FOMMEDRAFT_167963 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D FOMMEDRAFT_166873 glycoside hydrolase family 38 protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D FOMMEDRAFT_111148 aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D FOMMEDRAFT_171549 hypothetical protein K08330 ATG11; autophagy-related protein 11
D FOMMEDRAFT_171550 kinase-like protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D FOMMEDRAFT_115887 hypothetical protein K21996 SNX41_42; sorting nexin-41/42
D FOMMEDRAFT_82758 lipid binding protein K17919 SNX4; sorting nexin-4
D FOMMEDRAFT_104178 alpha/beta-hydrolase K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D FOMMEDRAFT_119753 alpha/beta-hydrolase K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D FOMMEDRAFT_77368 alpha/beta-hydrolase K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D FOMMEDRAFT_28851 hypothetical protein K21141 ATG27; autophagy-related protein 27
D FOMMEDRAFT_19196 ARM repeat-containing protein K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D FOMMEDRAFT_171549 hypothetical protein K08330 ATG11; autophagy-related protein 11
D FOMMEDRAFT_171550 kinase-like protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D FOMMEDRAFT_23726 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D FOMMEDRAFT_167441 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D FOMMEDRAFT_168547 hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
D FOMMEDRAFT_21699 hypothetical protein K00844 HK; hexokinase [EC:2.7.1.1]
D FOMMEDRAFT_158668 Tom7-domain-containing protein K17771 TOM7; mitochondrial import receptor subunit TOM7
B Pexophagy
C Selective cargos
D FOMMEDRAFT_147078 hypothetical protein K13336 PEX3; peroxin-3
D FOMMEDRAFT_106129 hypothetical protein K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D FOMMEDRAFT_167441 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
D FOMMEDRAFT_129343 AAA-domain-containing protein K13338 PEX1; peroxin-1
D FOMMEDRAFT_109196 AAA-domain-containing protein K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D FOMMEDRAFT_167441 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
C Other aggrephagy associated proteins
D FOMMEDRAFT_164470 AAA ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
D FOMMEDRAFT_18146 histone deacetylase clr3 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
B Xenophagy
C Cargo receptors
D FOMMEDRAFT_167441 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B ER-phagy
C ER-phagy recepters
D FOMMEDRAFT_23136 translocation protein K12275 SEC62; translocation protein SEC62
C Other ER-phagy associated proteins
D FOMMEDRAFT_96000 Calreticulin-domain-containing protein K08054 CANX; calnexin
D FOMMEDRAFT_22191 cytochrome b5 K17278 PGRMC1_2; membrane-associated progesterone receptor component
D FOMMEDRAFT_85087 progesterone binding protein K17278 PGRMC1_2; membrane-associated progesterone receptor component
D FOMMEDRAFT_149324 VAMP-associated protein K06096 VAPA; vesicle-associated membrane protein-associated protein A
C ER stress-related proteins
D FOMMEDRAFT_166523 heat shock protein 70 K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D FOMMEDRAFT_170806 chaperone protein BipA K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D FOMMEDRAFT_126253 heat shock protein Hsp90 K09487 HSP90B; heat shock protein 90kDa beta
D FOMMEDRAFT_30081 ribosomal protein S5 domain 2-like protein K09487 HSP90B; heat shock protein 90kDa beta
D FOMMEDRAFT_171157 hypothetical protein K03237 EIF2S1; translation initiation factor 2 subunit 1
B Chaperone mediated autophagy (CMA)
C Selective cargos
D FOMMEDRAFT_170809 aldolase K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D FOMMEDRAFT_132275 aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D FOMMEDRAFT_132890 glyceraldehyde 3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D FOMMEDRAFT_106158 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D FOMMEDRAFT_17908 ubiquitin-domain-containing protein K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D FOMMEDRAFT_124771 heat shock protein HSS1 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D FOMMEDRAFT_18191 heat shock protein 70 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D FOMMEDRAFT_104145 HSP90-domain-containing protein K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D FOMMEDRAFT_140043 translation elongation factor K03231 EEF1A; elongation factor 1-alpha
D FOMMEDRAFT_118650 serine carboxypeptidase K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
D FOMMEDRAFT_164247 alpha/beta-hydrolase K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D FOMMEDRAFT_19196 ARM repeat-containing protein K08332 VAC8; vacuolar protein 8
C Midbophagy
D FOMMEDRAFT_167441 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D FOMMEDRAFT_23726 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D FOMMEDRAFT_164321 atypical/PIKK/FRAP protein kinase K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D FOMMEDRAFT_138645 WD40 repeat-like protein K08266 MLST8; target of rapamycin complex subunit LST8
D FOMMEDRAFT_21560 hypothetical protein K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D FOMMEDRAFT_164321 atypical/PIKK/FRAP protein kinase K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D FOMMEDRAFT_138645 WD40 repeat-like protein K08266 MLST8; target of rapamycin complex subunit LST8
D FOMMEDRAFT_135700 SIN1-domain-containing protein K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D FOMMEDRAFT_96298 hypothetical protein K08267 RICTOR; rapamycin-insensitive companion of mTOR
D FOMMEDRAFT_147945 ankyrin K25576 AVO2; target of rapamycin complex 2 subunit AVO2
C SEACIT/GATOR1 complex
D FOMMEDRAFT_20964 hypothetical protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D FOMMEDRAFT_120503 hypothetical protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D FOMMEDRAFT_126632 WD40 repeat-like protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D FOMMEDRAFT_101954 hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D FOMMEDRAFT_168027 WD40 repeat-like protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D FOMMEDRAFT_165850 WD40 repeat-like protein K14299 SEH1; nucleoporin SEH1
D FOMMEDRAFT_30574 WD40 repeat-like protein K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D FOMMEDRAFT_18002 GTP-binding protein ypt1 K07874 RAB1A; Ras-related protein Rab-1A
D FOMMEDRAFT_107155 GTP-binding protein SAS1 K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D FOMMEDRAFT_131457 serine/threonine protein phosphatase 2A K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D FOMMEDRAFT_19606 hypothetical protein K21249 UVRAG; UV radiation resistance-associated gene protein
D FOMMEDRAFT_93870 autophagy-type protein 22 K06902 UMF1; MFS transporter, UMF1 family
D FOMMEDRAFT_138660 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D FOMMEDRAFT_147956 WD40 repeat-like protein K22991 WDR45; WD repeat-containing protein 45
D FOMMEDRAFT_88895 hypothetical protein K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
D FOMMEDRAFT_21571 UPF0183-domain-containing protein K27411 PHAF1; phagosome assembly factor 1
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AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D FOMMEDRAFT_19323 NADPH oxidase isoform 1 K08008 NOX1; NADPH oxidase 1
D FOMMEDRAFT_111964 NADPH oxidase isoform 2 K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
C Nox associated proteins
B Actin-binding proteins
C Myosins
D FOMMEDRAFT_106001 hypothetical protein K10356 MYO1; myosin I
D FOMMEDRAFT_103814 myosin 5 K10357 MYO5; myosin V
C Arp2/3 complex
D FOMMEDRAFT_124546 actin-related protein ARPC3 K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D FOMMEDRAFT_122862 actin-related protein ARPC2 K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D FOMMEDRAFT_169456 actin-related protein ARPC3 K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D FOMMEDRAFT_108293 arp2/3 complex K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D FOMMEDRAFT_139721 actin-related protein ARPC5 K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D FOMMEDRAFT_99057 Actin/actin-like protein K17260 ACTR2; actin-related protein 2
D FOMMEDRAFT_103037 actin binding protein K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D FOMMEDRAFT_144346 WH1-domain-containing protein K23612 WASL; neural Wiskott-Aldrich syndrome protein
D FOMMEDRAFT_117069 hypothetical protein K20520 DBNL; drebrin-like protein
D FOMMEDRAFT_145486 hypothetical protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D FOMMEDRAFT_122221 BAR-domain-containing protein K12562 AMPH; amphiphysin
D FOMMEDRAFT_141675 hypothetical protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D FOMMEDRAFT_70409 hypothetical protein K20521 BBC1; myosin tail region-interacting protein MTI1
D FOMMEDRAFT_138398 hypothetical protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D FOMMEDRAFT_138535 SH3-domain-containing protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D FOMMEDRAFT_171255 DUF500-domain-containing protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D FOMMEDRAFT_81868 DUF500-domain-containing protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D FOMMEDRAFT_82732 hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D FOMMEDRAFT_156678 hypothetical protein K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D FOMMEDRAFT_16456 profilin K05759 PFN; profilin
D FOMMEDRAFT_119381 hypothetical protein K17261 CAP1_2; adenylyl cyclase-associated protein
D FOMMEDRAFT_104478 kinesin heavy chain K10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]
B Mucins
C Membrane bound mucins
C Secretory mucins
B MARVEL domain-containing proteins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
C Lipid droplets
D FOMMEDRAFT_111911 ras-domain-containing protein K07910 RAB18; Ras-related protein Rab-18
D FOMMEDRAFT_108604 hypothetical protein K28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D FOMMEDRAFT_95181 RhoGAP-domain-containing protein K18470 ARHGAP1; Rho GTPase-activating protein 1
D FOMMEDRAFT_101704 RhoGAP-domain-containing protein K20630 CHN1_2; chimaerin
D FOMMEDRAFT_168366 hypothetical protein K20649 ARHGAP39; Rho GTPase-activating protein 39
D FOMMEDRAFT_100931 RhoGAP-domain-containing protein K20643 RGD1; Rho GTPase-activating protein RGD1
D FOMMEDRAFT_143907 RhoGAP-domain-containing protein K08773 RALBP1; RalA-binding protein 1
C Rho guanine nucleotide exchange factors (GEFs)
D FOMMEDRAFT_144281 hypothetical protein K20705 DNMBP; dynamin-binding protein
D FOMMEDRAFT_168262 cytoplasmic protein K05727 DOCK3; dedicator of cytokinesis protein 3
D FOMMEDRAFT_104451 hypothetical protein K27817 RAP1GDS1; Rap1 GTPase-GDP dissociation stimulator 1
D FOMMEDRAFT_169942 hypothetical protein K28415 DENND11; DENN domain-containing protein 11
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 7, 2025