+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Gymnogyps californianus (California condor)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 127013430 mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 127014537 mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 127014500 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 127021112 cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 127020572 RNA guanine-N7 methyltransferase activating subunit isoform X1 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 127027818 nuclear cap-binding protein subunit 1 isoform X1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 127029009 nuclear cap-binding protein subunit 1-like K12882 NCBP1; nuclear cap-binding protein subunit 1
E 127019610 nuclear cap-binding protein subunit 2 isoform X1 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 127020208 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 127021199 cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 127016635 cleavage and polyadenylation specificity factor subunit 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 127028187 cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 127029561 pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 127016561 cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 127014469 cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 127022226 cleavage and polyadenylation specificity factor subunit 4 isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 127024177 putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 127015475 pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 127019711 pre-mRNA 3'-end-processing factor FIP1-like K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 127020115 pre-mRNA 3' end processing protein WDR33 K15542 PFS2; polyadenylation factor subunit 2
E 127021600 WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 127014111 serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 127022875 serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 127024697 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 127023315 cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 127017300 cleavage stimulation factor subunit 3 isoform X1 K14408 CSTF3; cleavage stimulation factor subunit 3
D U7-dependent histone pre-mRNA processing factors
E 127023363 small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 127023069 small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 127026258 small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 127029369 small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 127025385 small nuclear ribonucleoprotein G isoform X1 K11099 SNRPG; small nuclear ribonucleoprotein G
E 127025151 U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 127021901 U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 127016561 cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 127014469 cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 127015420 uncharacterized protein LOC127015420 K18710 SLBP; histone RNA hairpin-binding protein
E 127015878 histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 127014377 LOW QUALITY PROTEIN: CASP8-associated protein 2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 127024387 transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
D N6-methyltransferase complex
E 127016164 N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 127013338 N(6)-adenine-specific methyltransferase METTL4 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 127018547 RNA N6-adenosine-methyltransferase METTL16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 127015285 pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 127012753 protein virilizer homolog K22910 VIRMA; protein virilizer
E 127021480 LOW QUALITY PROTEIN: putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 127026261 RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 127014392 zinc finger CCCH domain-containing protein 13 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 127029586 E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 127014206 poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 127017431 poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 127027443 poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 127018451 LOW QUALITY PROTEIN: BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 127029577 RNA-binding protein 26 isoform X1 K13192 RBM26; RNA-binding protein 26
E 127021172 alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 127022367 RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 127024701 TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 127024462 probable ATP-dependent RNA helicase DHX40 isoform X1 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 127019635 DNA/RNA-binding protein KIN17 isoform X1 K13102 KIN; DNA/RNA-binding protein KIN17
D 127018169 tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 127022353 methyltransferase-like protein 22 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 127014929 terminal nucleotidyltransferase 5A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 127029380 terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 127019749 LOW QUALITY PROTEIN: terminal nucleotidyltransferase 5D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 127016952 zinc finger CCCH domain-containing protein 14 isoform X1 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 127019171 protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 127024023 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 127014657 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 127021650 LOW QUALITY PROTEIN: coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 127026406 protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 127028365 histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 127016784 pinin K13114 PNN; pinin
E 127022317 RNA-binding protein with serine-rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 127024944 serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 127013085 THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 127019486 THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E 127024023 THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 127022779 THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 127021507 THO complex subunit 7 homolog isoform X1 K13176 THOC7; THO complex subunit 7
E 127026919 chromatin target of PRMT1 protein K28424 CHTOP; chromatin target of PRMT1 protein
D TREX-2 complex
E 127029631 PCI domain-containing protein 2 isoform X1 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 127013574 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 127012925 transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 127019537 centrin-2 K10840 CETN2; centrin-2
E 127027091 centrin-3 K16466 CETN3; centrin-3
E 127018177 LOW QUALITY PROTEIN: germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 127018993 nucleoprotein TPR K09291 TPR; nucleoprotein TPR
E 127023393 mRNA export factor RAE1 isoform X1 K14298 RAE1; mRNA export factor
E 127021626 protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 127020800 nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 127024105 nuclear pore complex protein Nup85 isoform X1 K14304 NUP85; nuclear pore complex protein Nup85
E 127014563 nucleoporin Nup43 isoform X1 K14305 NUP43; nuclear pore complex protein Nup43
E 127029354 nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 127016131 nucleoporin p54 isoform X1 K14308 NUP54; nuclear pore complex protein Nup54
E 127019481 nuclear pore glycoprotein p62-like isoform X1 K14306 NUP62; nuclear pore complex protein Nup62
E 127019482 nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 127024433 nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 127021221 nuclear pore complex protein Nup93 K14309 NUP93; nuclear pore complex protein Nup93
E 127029699 nuclear pore complex protein Nup98-Nup96 isoform X1 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 127024440 nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 127014312 nuclear pore complex protein Nup133 isoform X1 K14300 NUP133; nuclear pore complex protein Nup133
E 127023615 nucleoporin NUP188 K14311 NUP188; nuclear pore complex protein Nup188
E 127013740 nuclear pore complex protein Nup153 K14296 NUP153; nuclear pore complex protein Nup153
E 127027083 nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 127028948 LOW QUALITY PROTEIN: nuclear pore complex protein Nup155-like K14312 NUP155; nuclear pore complex protein Nup155
E 127016455 nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 127018267 nucleoporin NUP35 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 127018688 nuclear pore complex protein Nup205 isoform X1 K14310 NUP205; nuclear pore complex protein Nup205
E 127021448 nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 127023612 nuclear pore complex protein Nup214 K14317 NUP214; nuclear pore complex protein Nup214
E 127024571 nuclear envelope pore membrane protein POM 121 K14316 POM121; nuclear pore complex protein Nup121
E 127020039 nucleoporin p58/p45 isoform X1 K14307 NUPL1; nucleoporin p58/p45
E 127012953 nucleoporin NUP42 isoform X1 K14321 NUPL2; nucleoporin-like protein 2
E 127019376 nucleoporin NDC1 K14315 NDC1; nucleoporin NDC1
E 127013120 nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 127029393 ranBP2-like and GRIP domain-containing protein 4 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 127020087 sentrin-specific protease 2 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 127027091 centrin-3 K16466 CETN3; centrin-3
E 127023780 mRNA export factor GLE1 K18723 GLE1; nucleoporin GLE1
E 127019667 NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 127022911 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 127020410 acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 127025591 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 127025679 ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 127019036 ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 127027128 ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 127028719 LOW QUALITY PROTEIN: ELAV-like protein 3 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 127022131 FAS-associated factor 2 K18726 FAF2; FAS-associated factor 2
E 127027123 transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 127017100 protein N-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 127014102 exportin-1 K14290 XPO1; exportin-1
E 127025217 exportin-7 isoform X1 K18460 XPO7; exportin-7
E 127022017 ran-binding protein 17 K24115 RANBP17; Ran-binding protein 17
E 127025275 ran GTPase-activating protein 1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 127024521 TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 127015458 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 127020033 eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 127019916 eukaryotic initiation factor 4A-II isoform X1 K03257 EIF4A; translation initiation factor 4A
E 127016494 eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 127024792 eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 127024309 eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 127025332 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 127017770 eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 127022110 eukaryotic translation initiation factor 4E-binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 127022906 eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 127014316 protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 127016610 protein angel homolog 1 isoform X1 K18729 ANGEL; protein angel
E 127019520 fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 127020285 RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 127021815 cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 127029708 cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 127022171 gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 127015597 transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 127015949 cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127017908 cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127020477 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127022134 cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127029552 ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 127020377 GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 127023189 polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 127025061 polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 127029921 polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 127027426 polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 127028864 polyadenylate-binding protein-interacting protein 1-like isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 127015774 polyadenylate-binding protein-interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 127022105 polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 127028197 LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 2B-like K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 127017080 deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 127019502 malignant T-cell-amplified sequence 1 isoform X1 K07575 MCTS; malignant T-cell-amplified sequence
E 127022850 density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 127015935 C->U-editing enzyme APOBEC-1-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 127017784 APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 127018728 heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 127022830 RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 127024311 RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 127025545 DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 127014962 HBS1-like protein K14416 HBS1; elongation factor 1 alpha-like protein
E 127027465 protein pelota homolog K06965 PELO; protein pelota
E 127021318 embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 127024718 LOW QUALITY PROTEIN: ATP-dependent RNA helicase DDX19B-like K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 127025787 ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 127025021 regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 127020574 la-related protein 6 K18733 LARP6; la-related protein 6
E 127025595 la-related protein 6-like K18733 LARP6; la-related protein 6
E 127022008 transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 127025351 transcriptional activator protein Pur-beta isoform X1 K21799 PURB; transcriptional activator protein Pur-beta
E 127017311 polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 127026368 zinc finger CCCH domain-containing protein 11A isoform X1 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 127020596 protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 127022012 eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 127022304 eukaryotic peptide chain release factor GTP-binding subunit ERF3A K03267 ERF3; peptide chain release factor subunit 3
E 127025416 regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 127029353 regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 127019670 regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 127020311 regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 127015565 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 127021867 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 127015842 protein phosphatase 2, regulatory subunit B, gamma isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 127017675 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 127021878 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 127025285 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 127016700 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 127020120 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 127029382 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 127013970 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 127014093 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 127016917 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 127017434 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 127022647 serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 127026955 nonsense-mediated mRNA decay factor SMG5 isoform X1 K11125 SMG5; protein SMG5
E 127024590 telomerase-binding protein EST1A K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 127018857 nonsense-mediated mRNA decay factor SMG7 isoform X1 K14409 SMG7; protein SMG7
E 127024607 nonsense-mediated mRNA decay factor SMG8 K18734 SMG8; protein SMG8
E 127020377 GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 127020428 selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 127027174 selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 127029749 GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 127027379 pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 127020420 unconventional myosin-Vc K10357 MYO5; myosin V
E 127020447 unconventional myosin-Va K10357 MYO5; myosin V
E 127025711 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 127027250 unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 127018936 protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
E 127021469 protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 127016350 piRNA biogenesis protein EXD1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 127020794 actin, cytoplasmic type 5 isoform X1 K05692 ACTB_G1; actin beta/gamma 1
E 127022299 actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 127013719 myelin basic protein K17269 MBP; myelin basic protein
E 127029880 vimentin K07606 VIM; vimentin
E 127021057 metallothionein-1 K14739 MT1_2; metallothionein 1/2
E 127013024 myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 127025615 embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 127023030 T-box-containing protein TBX6L K10180 TBX6; T-box protein 6
E 127017941 nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 127019038 far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 127023634 far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 127015324 elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 127023179 elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 127012887 heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 127020223 arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 127012574 double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 127023178 double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 127013540 insulin-like growth factor 2 mRNA-binding protein 3 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 127025459 polypyrimidine tract-binding protein 1 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 127015949 cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127017908 cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127020477 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127022134 cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 127019520 fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 127020285 RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 127021815 cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 127029708 cytoplasmic FMR1-interacting protein 1 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 127012593 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 127018194 poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 127021406 poly(rC)-binding protein 4 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 127016371 caprin-1 isoform X1 K18743 CAPRIN1; caprin-1
E 127019697 caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 127024717 Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 127019935 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 127012527 protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 127025012 protein argonaute-3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 127025197 protein argonaute-4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 127025198 protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 127015458 eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 127020033 eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 127025416 regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 127029552 ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 127025799 probable ATP-dependent RNA helicase DDX6 isoform X1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 127020595 RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 127025504 RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 127027025 LOW QUALITY PROTEIN: RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 127027559 LOW QUALITY PROTEIN: RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 127012729 LOW QUALITY PROTEIN: fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 127020958 protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 127023284 protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 127024717 Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 127013775 LIM domain-containing protein 1 isoform X1 K16682 AJUBA; LIM domain-containing protein
E 127021251 LOW QUALITY PROTEIN: Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 127015935 C->U-editing enzyme APOBEC-1-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 127026125 helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 127025155 proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 127027082 transportin-1 K18752 TNPO1; transportin-1
E 127029094 LOW QUALITY PROTEIN: transportin-1-like K18752 TNPO1; transportin-1
E 127022647 serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 127026955 nonsense-mediated mRNA decay factor SMG5 isoform X1 K11125 SMG5; protein SMG5
E 127024590 telomerase-binding protein EST1A K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 127018857 nonsense-mediated mRNA decay factor SMG7 isoform X1 K14409 SMG7; protein SMG7
E 127014589 LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2 K18753 ZFP36L; butyrate response factor
E 127017149 mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 127014446 protein lin-28 homolog B isoform X1 K18754 LIN28; protein lin-28
E 127025160 protein lin-28 homolog A K18754 LIN28; protein lin-28
E 127016217 huntingtin K04533 HD; huntingtin
E 127014775 importin-8 K18755 IPO8; importin-8
E 127017781 protein bicaudal C homolog 1 K18756 BICC1; protein bicaudal C
E 127018728 heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 127019058 cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 127015444 la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 127021853 LOW QUALITY PROTEIN: la-related protein 1 K18757 LARP1; la-related protein 1
E 127023083 ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 127021580 mRNA-decapping enzyme 1A isoform X1 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 127013825 mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 127025394 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 127021614 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 127025637 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 127015978 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 127025565 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 127021136 LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 127015347 kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 127017402 kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 127020420 unconventional myosin-Vc K10357 MYO5; myosin V
E 127020447 unconventional myosin-Va K10357 MYO5; myosin V
E 127025711 unconventional myosin-Vb-like K10357 MYO5; myosin V
E 127027250 unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 127012944 tubulin alpha-4 chain K07374 TUBA; tubulin alpha
E 127012949 tubulin alpha-4 chain-like K07374 TUBA; tubulin alpha
E 127016297 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 127017065 tubulin alpha-3 chain-like isoform X1 K07374 TUBA; tubulin alpha
E 127018153 tubulin alpha-5 chain K07374 TUBA; tubulin alpha
E 127019912 tubulin alpha-3 chain isoform X1 K07374 TUBA; tubulin alpha
E 127026170 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 127029055 tubulin alpha-8 chain-like K07374 TUBA; tubulin alpha
E 127029062 LOW QUALITY PROTEIN: tubulin alpha chain-like K07374 TUBA; tubulin alpha
E 127015949 cytoplasmic polyadenylation element-binding protein 2 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127017908 cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127020477 cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127022134 cytoplasmic polyadenylation element-binding protein 4 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 127022171 gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 127015597 transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 127022292 trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 127023902 trinucleotide repeat-containing gene 6C protein K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 127029779 trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 127021346 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 127016775 CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 127022030 CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 127015403 CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 127021897 CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 127015629 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 127022108 CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 127021077 granule associated Rac and RHOG effector protein 1 isoform X1 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 127019906 DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 127015145 LOW QUALITY PROTEIN: PAN2-PAN3 deadenylation complex subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 127020374 protein Tob2 K14443 TOB; protein Tob/BTG
E 127021425 protein BTG1-like K14443 TOB; protein Tob/BTG
E 127024068 protein Tob1 K14443 TOB; protein Tob/BTG
E 127025863 protein BTG4 isoform X1 K14443 TOB; protein Tob/BTG
E 127026167 protein BTG2 K14443 TOB; protein Tob/BTG
E 127028700 protein BTG1 isoform X1 K14443 TOB; protein Tob/BTG
E 127022906 eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 127016766 protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 127020865 enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 127021061 LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 127029353 regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 127019670 regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 127020311 regulator of nonsense transcripts 3A K14328 UPF3; regulator of nonsense transcripts 3
E 127013296 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 127015326 interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 127015531 LOW QUALITY PROTEIN: zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 127024771 ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 127023220 YTH domain-containing family protein 1 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 127025156 YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
E 127029953 YTH domain-containing family protein 3 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 127017482 nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 127025290 cytotoxic granule associated RNA binding protein TIA1 isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 127023189 polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 127025061 polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 127029921 polyadenylate-binding protein 1 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 127012574 double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 127023178 double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 127019520 fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 127020285 RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 127025679 ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 127022046 ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 127015773 LOW QUALITY PROTEIN: ras GTPase-activating protein-binding protein 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 127020257 eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 127022312 eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 127019916 eukaryotic initiation factor 4A-II isoform X1 K03257 EIF4A; translation initiation factor 4A
E 127014657 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 127016494 eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 127024792 eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 127014138 ribosomal protein S6 kinase alpha-2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127019496 ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025060 ribosomal protein S6 kinase alpha-1 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025932 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025933 ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025934 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025935 ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025937 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025941 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025955 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025991 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127025997 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127026002 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127026004 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127026015 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127026017 ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127026018 ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127026020 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-3-like K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127029722 ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 127029189 LOW QUALITY PROTEIN: receptor of activated protein C kinase 1-like K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 127023695 TNF receptor-associated factor 2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 127015054 tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 127013007 la-related protein 4B K18763 LARP4; la-related protein 4
E 127028387 la-related protein 4 isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 127021580 mRNA-decapping enzyme 1A isoform X1 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 127013825 mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 127025799 probable ATP-dependent RNA helicase DDX6 isoform X1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 127020865 enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 127021061 LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 127016766 protein PAT1 homolog 1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 127025394 U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 127021614 U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 127025637 U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 127015978 U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 127025565 U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 127021136 LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 127019935 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 127014867 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 127025823 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 127024136 probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 127017753 exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
E 127023596 exosome complex component RRP4 isoform X1 K03679 RRP4; exosome complex component RRP4
E 127018074 exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 127028057 exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 127020926 exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 127012940 exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 127029495 exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 127015595 exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 127028490 exosome complex exonuclease RRP44 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 127020439 DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 127024919 LOW QUALITY PROTEIN: exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 127014596 nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 127021290 M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 127015600 probable ATP-dependent RNA helicase DDX60 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 127013292 terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 127020995 terminal nucleotidyltransferase 4B isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 127027717 zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 127027195 exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 127027284 tetratricopeptide repeat protein 37 K12600 SKI3; superkiller protein 3
E 127020874 WD repeat-containing protein 61 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 127015403 CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 127021897 CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 127021346 CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 127016775 CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 127022030 CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 127015629 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 127022108 CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 127018679 CCR4-NOT transcription complex subunit 9 isoform X1 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 127013111 CCR4-NOT transcription complex subunit 10 isoform X1 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 127015145 LOW QUALITY PROTEIN: PAN2-PAN3 deadenylation complex subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 127014645 poly(A)-specific ribonuclease PNLDC1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 127022439 poly(A)-specific ribonuclease PARN isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 127020002 ATP-dependent DNA/RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 127020374 protein Tob2 K14443 TOB; protein Tob/BTG
E 127021425 protein BTG1-like K14443 TOB; protein Tob/BTG
E 127024068 protein Tob1 K14443 TOB; protein Tob/BTG
E 127025863 protein BTG4 isoform X1 K14443 TOB; protein Tob/BTG
E 127026167 protein BTG2 K14443 TOB; protein Tob/BTG
E 127028700 protein BTG1 isoform X1 K14443 TOB; protein Tob/BTG
E 127015925 nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 127016318 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 127022250 ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 127025823 m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 127021499 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 127020684 iron-responsive element-binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 127024136 probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 127023373 helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 127017086 nuclear exosome regulator NRDE2 isoform X1 K26109 NRDE2; nuclear exosome regulator NRDE2
E 127016735 protein Smaug homolog 1 isoform X1 K27396 SMG; protein Smaug
E 127027294 focadhesin K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 127015181 probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 127019681 probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 127024668 probable ribonuclease ZC3H12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 127025176 LOW QUALITY PROTEIN: endoribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
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AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 127013232 ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 127025741 oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 127019680 gamma-enolase isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 127024706 alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 127014843 polyribonucleotide nucleotidyltransferase 1, mitochondrial K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 127013795 ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 127019957 ATP-dependent 6-phosphofructokinase, liver type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 127021886 stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 127018392 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 127023596 exosome complex component RRP4 isoform X1 K03679 RRP4; exosome complex component RRP4
E 127017753 exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 127012940 exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 27, 2025