+F Repair protein KO
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DNA Repair and Recombination Proteins - Geobacter pickeringii
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E GPICK_01310 single-stranded DNA-binding protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E GPICK_07965 endonuclease III K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E GPICK_08880 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D GPICK_01460 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GPICK_05605 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GPICK_11880 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GPICK_07895 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D GPICK_04265 6-O-methylguanine DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E GPICK_01310 single-stranded DNA-binding protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E GPICK_11045 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E GPICK_07965 endonuclease III K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E GPICK_13605 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E GPICK_04365 5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E GPICK_08880 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E GPICK_13720 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E GPICK_03690 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E GPICK_11280 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E GPICK_13670 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E GPICK_00675 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E GPICK_04390 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E GPICK_14770 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E GPICK_14815 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E GPICK_00380 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GPICK_11270 ATP-dependent DNA helicase Rep K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GPICK_13670 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E GPICK_11280 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F GPICK_03295 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F GPICK_03300 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F GPICK_03450 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F GPICK_10355 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F GPICK_16400 helicase K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E GPICK_06525 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E GPICK_13625 DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E GPICK_09185 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E GPICK_07260 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E GPICK_07265 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E GPICK_10780 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E GPICK_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E GPICK_10215 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E GPICK_10320 ATPase AAA K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E GPICK_09710 exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E GPICK_15670 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E GPICK_11280 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E GPICK_00380 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GPICK_11270 ATP-dependent DNA helicase Rep K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E GPICK_02130 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E GPICK_06990 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E GPICK_06985 exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E GPICK_01415 recombinase RecA K03553 recA; recombination protein RecA
E GPICK_05160 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E GPICK_05165 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E GPICK_05155 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E GPICK_15225 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E GPICK_01415 recombinase RecA K03553 recA; recombination protein RecA
E GPICK_15060 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E GPICK_00015 DNA replication protein RecF K03629 recF; DNA replication and repair protein RecF
E GPICK_09815 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E GPICK_03690 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E GPICK_13565 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E GPICK_15660 recombinase RecR K06187 recR; recombination protein RecR
E GPICK_05395 DNA recombination protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E GPICK_01350 exonuclease K03554 rdgC; recombination associated protein RdgC
E GPICK_05160 ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E GPICK_05165 ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E GPICK_05155 Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E GPICK_09665 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
E GPICK_10870 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F GPICK_00025 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F GPICK_00020 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F GPICK_12560 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F GPICK_02095 transcriptional regulator HU subunit alpha K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F GPICK_03690 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F GPICK_13565 DNA recombination protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F GPICK_15660 recombinase RecR K06187 recR; recombination protein RecR
F GPICK_11280 NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F GPICK_01275 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F GPICK_08480 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F GPICK_08285 DNA-binding protein K05788 ihfB; integration host factor subunit beta
F GPICK_03750 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F GPICK_11235 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F GPICK_00675 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F GPICK_04390 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F GPICK_14770 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D GPICK_09195 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D GPICK_01415 recombinase RecA K03553 recA; recombination protein RecA
D GPICK_09205 LexA family transcriptional regulator K01356 lexA; repressor LexA [EC:3.4.21.88]
D GPICK_05395 DNA recombination protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D GPICK_02130 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D GPICK_01425 recombinase RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D GPICK_14510 helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D GPICK_01460 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GPICK_05605 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GPICK_11880 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D GPICK_07895 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D GPICK_05040 ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D GPICK_06250 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
C Others
D GPICK_07870 phosphoesterase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024