+D GENES KO
#
KEGG Orthology (KO) - Halalkaliarchaeum sp. AArc-CO
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:haaa00010]
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D AArcCO_0213 porA2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D AArcCO_0214 porB2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
C 00020 Citrate cycle (TCA cycle) [PATH:haaa00020]
D AArcCO_0213 porA2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D AArcCO_0214 porB2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D AArcCO_0215 porG2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D AArcCO_0212 Ferredoxin K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:haaa00030]
D AArcCO_0262 wcaG; Nucleoside-diphosphate-sugar epimerase K19243 azf; NAD+ dependent glucose-6-phosphate dehydrogenase [EC:1.1.1.388]
D AArcCO_0113 rpiA; Ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D AArcCO_0152 rbsK; Sugar kinase, ribokinase family K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D AArcCO_0011 Aldehyde:ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
C 00040 Pentose and glucuronate interconversions
C 00051 Fructose and mannose metabolism
C 00052 Galactose metabolism
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism
C 00520 Amino sugar and nucleotide sugar metabolism
C 00620 Pyruvate metabolism [PATH:haaa00620]
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D AArcCO_0213 porA2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D AArcCO_0214 porB2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:haaa00630]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AArcCO_0133 pucG; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
C 00640 Propanoate metabolism
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00650 Butanoate metabolism [PATH:haaa00650]
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D AArcCO_0213 porA2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D AArcCO_0214 porB2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D AArcCO_0282 pksG; 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00660 C5-Branched dibasic acid metabolism
C 00562 Inositol phosphate metabolism
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:haaa00190]
D AArcCO_0036 ntpA; Archaeal/vacuolar-type H+-ATPase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D AArcCO_0037 ntpB; Archaeal/vacuolar-type H+-ATPase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D AArcCO_0034 ntpC; Archaeal/vacuolar-type H+-ATPase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D AArcCO_0038 ntpD; Archaeal/vacuolar-type H+-ATPase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D AArcCO_0033 ntpE; Archaeal/vacuolar-type H+-ATPase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D AArcCO_0035 ntpG; Archaeal/vacuolar-type H+-ATPase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D AArcCO_0030 ntpF; Archaeal/vacuolar-type H+-ATPase subunit H K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D AArcCO_0031 ntpI; Archaeal/vacuolar-type H+-ATPase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D AArcCO_0032 ntpK; Archaeal/vacuolar-type H+-ATPase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D AArcCO_0073 ppa; Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:haaa00710]
D AArcCO_0113 rpiA; Ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:haaa00720]
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AArcCO_0213 porA2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D AArcCO_0214 porB2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D AArcCO_0215 porG2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00177 korC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]
D AArcCO_0212 Ferredoxin K00176 korD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]
C 00680 Methane metabolism [PATH:haaa00680]
D AArcCO_0133 pucG; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D AArcCO_0216 hdrA; Heterodisulfide reductase, subunit A or related polyferredoxin K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D AArcCO_0060 serB; Phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 00910 Nitrogen metabolism
D AArcCO_0179 Hydroxylamine reductase, 6Fe-6S prismane cluster-containing protein K05601 hcp; hydroxylamine reductase [EC:1.7.99.1]
C 00920 Sulfur metabolism [PATH:haaa00920]
D AArcCO_0203 cysH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase or related enzyme K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D AArcCO_0237 met2; Homoserine acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:haaa00061]
D AArcCO_0200 fabG; Short-chain alcohol dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
D AArcCO_0293 caiA; Acyl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism
C 00564 Glycerophospholipid metabolism [PATH:haaa00564]
D AArcCO_0174 fixC; Dehydrogenase (flavoprotein) K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism
D AArcCO_0051 guaA; GMP synthase, PP-ATPase domain/subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AArcCO_0253 guaA2; GMP synthase - Glutamine amidotransferase domain K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C 00240 Pyrimidine metabolism [PATH:haaa00240]
D AArcCO_0050 pyrG; CTP synthase (UTP-ammonia lyase) K01937 pyrG; CTP synthase [EC:6.3.4.2]
D AArcCO_0049 upp; Uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:haaa00250]
D AArcCO_0133 pucG; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D AArcCO_0204 proC; Alanine dehydrogenase/(1)-pyrroline-2-carboxylate reductase ProC K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D AArcCO_0048 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D AArcCO_0047 argH; Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
C 00260 Glycine, serine and threonine metabolism [PATH:haaa00260]
D AArcCO_0195 thrC; Threonine synthase and cysteate synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D AArcCO_0133 pucG; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D AArcCO_0060 serB; Phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D AArcCO_0197 metC; Cystathionine beta-lyase/cystathionine gamma-synthase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
C 00270 Cysteine and methionine metabolism [PATH:haaa00270]
D AArcCO_0197 metC; Cystathionine beta-lyase/cystathionine gamma-synthase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D AArcCO_0092 ssnA; Cytosine deaminase or related metal-dependent hydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D AArcCO_0141 sam1; S-adenosylhomocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D AArcCO_0237 met2; Homoserine acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D AArcCO_0236 met17; O-acetylhomoserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D AArcCO_0078 ilvE; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0182 ilvE2; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0189 mdh; Malate/lactate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00280 Valine, leucine and isoleucine degradation [PATH:haaa00280]
D AArcCO_0078 ilvE; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0182 ilvE2; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0208 porD; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00188 vorD; 2-oxoisovalerate ferredoxin oxidoreductase delta subunit [EC:1.2.7.7]
D AArcCO_0282 pksG; 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:haaa00290]
D AArcCO_0078 ilvE; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0182 ilvE2; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00300 Lysine biosynthesis [PATH:haaa00300]
D AArcCO_0228 argE2; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D AArcCO_0046 lysW; Lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D AArcCO_0043 argB; Acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D AArcCO_0044 argC; Acetylglutamate semialdehyde dehydrogenase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D AArcCO_0042 argD; Ornithine/acetylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D AArcCO_0041 argE; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00310 Lysine degradation
D AArcCO_0293 caiA; Acyl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
C 00220 Arginine biosynthesis [PATH:haaa00220]
D AArcCO_0040 argF; Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D AArcCO_0048 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D AArcCO_0047 argH; Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D AArcCO_0046 lysW; Lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D AArcCO_0045 rimK; Glutathione synthase/glutaminyl transferase/alpha-L-glutamate ligase K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60]
D AArcCO_0043 argB; Acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D AArcCO_0044 argC; Acetylglutamate semialdehyde dehydrogenase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D AArcCO_0042 argD; Ornithine/acetylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D AArcCO_0041 argE; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00330 Arginine and proline metabolism
C 00340 Histidine metabolism [PATH:haaa00340]
D AArcCO_0150 hisI; Phosphoribosyl-ATP pyrophosphohydrolase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D AArcCO_0096 hisH; Glutamine amidotransferase K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D AArcCO_0017 hutH; Histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]
C 00350 Tyrosine metabolism
C 00360 Phenylalanine metabolism
C 00380 Tryptophan metabolism
D AArcCO_0293 caiA; Acyl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis
D AArcCO_0080 trpE; Anthranilate/para-aminobenzoate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D AArcCO_0079 pabA; Anthranilate/para-aminobenzoate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
C 00430 Taurine and hypotaurine metabolism [PATH:haaa00430]
D AArcCO_0131 ggt; Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D AArcCO_0204 proC; Alanine dehydrogenase/(1)-pyrroline-2-carboxylate reductase ProC K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:haaa00450]
D AArcCO_0197 metC; Cystathionine beta-lyase/cystathionine gamma-synthase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D AArcCO_0114 csdA; Selenocysteine lyase/Cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
C 00460 Cyanoamino acid metabolism [PATH:haaa00460]
D AArcCO_0131 ggt; Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C 00470 D-Amino acid metabolism
C 00480 Glutathione metabolism [PATH:haaa00480]
D AArcCO_0131 ggt; Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D AArcCO_0151 lpd; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component or related enzyme K03423 E1.8.1.13; bis-gamma-glutamylcystine reductase [EC:1.8.1.13]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism
C 00740 Riboflavin metabolism [PATH:haaa00740]
D AArcCO_0121 ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D AArcCO_0122 CTP-dependent Riboflavin kinase K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D AArcCO_0147 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:haaa00750]
D AArcCO_0195 thrC; Threonine synthase and cysteate synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D AArcCO_0149 pdx2; putative glutamine amidotransferase involved inpyridoxine biosynthesis K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism
C 00770 Pantothenate and CoA biosynthesis
D AArcCO_0078 ilvE; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0182 ilvE2; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00780 Biotin metabolism [PATH:haaa00780]
D AArcCO_0200 fabG; Short-chain alcohol dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00785 Lipoic acid metabolism [PATH:haaa00785]
D AArcCO_0108 lplA; Lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
C 00790 Folate biosynthesis [PATH:haaa00790]
D AArcCO_0007 mptA; Fe(2+)-dependent GTP cyclohydrolase K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D AArcCO_0132 mobA; Molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:haaa00860]
D AArcCO_0087 hemB; Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D AArcCO_0058 hemC; Porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D AArcCO_0059 hemD; Uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D AArcCO_0288 cobB; Cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:haaa00130]
D AArcCO_0147 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D AArcCO_0134 rspA; L-alanine-DL-glutamate epimerase or related enzyme of enolase superfamily K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D AArcCO_0135 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:haaa00900]
D AArcCO_0282 pksG; 3-hydroxy-3-methylglutaryl CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D AArcCO_0145 putative aconitase K25517 acnX1; phosphomecalonate degydratase large subunit [EC:4.2.1.182]
D AArcCO_0146 Swiveling domain associated with predicted aconitase K09128 acnX2; phosphomecalonate degydratase small subunit [EC:4.2.1.182]
D AArcCO_0144 ubiD; 3-polyprenyl-4-hydroxybenzoate decarboxylase or related decarboxylase K25518 E4.1.1.126; anhydromevalonate phosphate decarboxylase [EC:4.1.1.126]
D AArcCO_0147 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D AArcCO_0080 trpE; Anthranilate/para-aminobenzoate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D AArcCO_0079 pabA; Anthranilate/para-aminobenzoate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D AArcCO_0200 fabG; Short-chain alcohol dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
D AArcCO_0293 caiA; Acyl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
C 00627 Aminobenzoate degradation
D AArcCO_0147 ubiX; 3-polyprenyl-4-hydroxybenzoate decarboxylase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
D AArcCO_0209 porA; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0257 porA3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D AArcCO_0210 porB; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0256 porB3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D AArcCO_0207 porG; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0259 porG3; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D AArcCO_0258 porD2; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase
C 03022 Basal transcription factors [PATH:haaa03022]
D AArcCO_0021 sua7; Transcription initiation factor TFIIB, Brf1 subunit/Transcription initiation factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D AArcCO_0069 sua7-2; Transcription initiation factor TFIIB, Brf1 subunit/Transcription initiation factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D AArcCO_0190 dinG; Rad3-related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:haaa03010]
D AArcCO_0089 rpl31a; Ribosomal protein L31E K02910 RP-L31e; large subunit ribosomal protein L31e
D AArcCO_0088 rpl39; Ribosomal protein L39E K02924 RP-L39e; large subunit ribosomal protein L39e
D AArcCO_0235 hypothetical protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D AArcCO_0176 rpl20a; Ribosomal protein L20A (L18A) K02944 RP-LX; large subunit ribosomal protein LX
C 00970 Aminoacyl-tRNA biosynthesis [PATH:haaa00970]
D AArcCO_0223 valS; Valyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AArcCO_0123 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AArcCO_0175 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:haaa03060]
D AArcCO_0056 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D AArcCO_0178 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D AArcCO_0002 lepB; Signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system
C 03050 Proteasome
C 03018 RNA degradation
D AArcCO_0294 vacB; Exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:haaa03030]
D AArcCO_0070 rnhA; Ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D AArcCO_0003 hys2; Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D AArcCO_0143 Archaeal DNA polymerase II, large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D AArcCO_0028 mcm2; putative ATPase involved in replication control,Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
D AArcCO_0289 holB; ATPase involved in DNA replication HolB, large subunit K04800 rfcL; replication factor C large subunit
C 03410 Base excision repair [PATH:haaa03410]
D AArcCO_0107 nfo; Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D AArcCO_0099 recJ; Single-stranded DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:haaa03420]
D AArcCO_0188 uvrC; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D AArcCO_0190 dinG; Rad3-related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
C 03430 Mismatch repair [PATH:haaa03430]
D AArcCO_0181 mutS; Mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS
D AArcCO_0225 mutS2; DNA structure-specific ATPase involved in suppression of recombination, MutS family K07456 mutS2; DNA mismatch repair protein MutS2
D AArcCO_0099 recJ; Single-stranded DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
C 03440 Homologous recombination [PATH:haaa03440]
D AArcCO_0099 recJ; Single-stranded DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:haaa02010]
D AArcCO_0173 tbpA; ABC-type thiamine transport system, periplasmic component K02064 thiB; thiamine transport system substrate-binding protein
D AArcCO_0172 thiP; ABC-type Fe3+ transport system, permease component K02063 thiP; thiamine transport system permease protein
D AArcCO_0171 malK; ABC-type sugar transport system, ATPase component K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D AArcCO_0093 phnD; ABC-type phosphate/phosphonate transport system,periplasmic component K02044 phnD; phosphonate transport system substrate-binding protein
D AArcCO_0095 phnE; ABC-type phosphate/phosphonate transport system,permease component K02042 phnE; phosphonate transport system permease protein
D AArcCO_0094 phnC; ABC-type phosphate/phosphonate transport system,ATPase component K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D AArcCO_0277 ABC-2 family transporter K19341 nosY; Cu-processing system permease protein
D AArcCO_0278 ccmA2; ABC-type multidrug transport system, ATPase component K19340 nosF; Cu-processing system ATP-binding protein
D AArcCO_0279 Lipoprotein NosD family K07218 nosD; nitrous oxidase accessory protein
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:haaa03070]
D AArcCO_0178 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D AArcCO_0056 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
B
B 09132 Signal transduction
C 02020 Two-component system
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:haaa02024]
D AArcCO_0080 trpE; Anthranilate/para-aminobenzoate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D AArcCO_0079 pabA; Anthranilate/para-aminobenzoate synthase component II K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D AArcCO_0120 ddpA; ABC-type transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D AArcCO_0178 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
D AArcCO_0056 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:haaa01000]
C 01001 Protein kinases
C 01009 Protein phosphatases and associated proteins [BR:haaa01009]
D AArcCO_0274 gcd7; Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain K03238 EIF2S2; translation initiation factor 2 subunit 2
D AArcCO_0141 sam1; S-adenosylhomocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D AArcCO_0060 serB; Phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:haaa01002]
D AArcCO_0051 guaA; GMP synthase, PP-ATPase domain/subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AArcCO_0253 guaA2; GMP synthase - Glutamine amidotransferase domain K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D AArcCO_0261 Exosortase K24447 artA; archaeosortase A [EC:3.4.22.-]
D AArcCO_0276 Zn-dependent dipeptidase, microsomal dipeptidasehomolog K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D AArcCO_0228 argE2; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D AArcCO_0304 htpX; Zn-dependent protease with chaperone function K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D AArcCO_0002 lepB; Signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D AArcCO_0075 glpG; Membrane associated serine protease K07059 K07059; rhomboid family protein
D AArcCO_0131 ggt; Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C 01003 Glycosyltransferases
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:haaa01011]
D AArcCO_0261 Exosortase K24447 artA; archaeosortase A [EC:3.4.22.-]
C 01004 Lipid biosynthesis proteins [BR:haaa01004]
D AArcCO_0200 fabG; Short-chain alcohol dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:haaa01006]
D AArcCO_0135 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
C 01007 Amino acid related enzymes [BR:haaa01007]
D AArcCO_0175 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AArcCO_0123 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AArcCO_0223 valS; Valyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AArcCO_0042 argD; Ornithine/acetylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D AArcCO_0078 ilvE; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0182 ilvE2; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D AArcCO_0133 pucG; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:haaa03000]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
D AArcCO_0008 Sugar-specific transcriptional regulator TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D AArcCO_0247 Transcriptional regulator, contains HTH domain K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D AArcCO_0284 putative transcriptional regulator K07731 K07731; putative transcriptional regulator
D AArcCO_0140 nikR; Transcriptional regulator, CopG/Arc/MetJ family (DNA-binding and a metal-binding domains) K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D AArcCO_0184 nikR2; Transcriptional regulator, CopG/Arc/MetJ family (DNA-binding and a metal-binding domains) K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
C 03021 Transcription machinery [BR:haaa03021]
D AArcCO_0021 sua7; Transcription initiation factor TFIIB, Brf1 subunit/Transcription initiation factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D AArcCO_0069 sua7-2; Transcription initiation factor TFIIB, Brf1 subunit/Transcription initiation factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D AArcCO_0190 dinG; Rad3-related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03019 Messenger RNA biogenesis [BR:haaa03019]
D AArcCO_0294 vacB; Exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C 03041 Spliceosome
C 03011 Ribosome [BR:haaa03011]
D AArcCO_0089 rpl31a; Ribosomal protein L31E K02910 RP-L31e; large subunit ribosomal protein L31e
D AArcCO_0088 rpl39; Ribosomal protein L39E K02924 RP-L39e; large subunit ribosomal protein L39e
D AArcCO_0235 hypothetical protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D AArcCO_0176 rpl20a; Ribosomal protein L20A (L18A) K02944 RP-LX; large subunit ribosomal protein LX
C 03009 Ribosome biogenesis [BR:haaa03009]
D AArcCO_0083 rli1; Translation initiation factor RLI1 K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D AArcCO_0168 nog1; GTP-binding protein, GTP1/Obg family K06943 NOG1; nucleolar GTP-binding protein
D AArcCO_0090 tIF6; Translation initiation factor 6 (eIF-6) K03264 EIF6; translation initiation factor 6
D AArcCO_0077 sua5; tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
C 03016 Transfer RNA biogenesis [BR:haaa03016]
D AArcCO_0223 valS; Valyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AArcCO_0123 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D AArcCO_0175 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AArcCO_0077 sua5; tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D AArcCO_0118 ligT; 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D AArcCO_0245 rsmE; RNA base methyltransferase family enzyme K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D AArcCO_0294 vacB; Exoribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C 03012 Translation factors [BR:haaa03012]
D AArcCO_0274 gcd7; Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain K03238 EIF2S2; translation initiation factor 2 subunit 2
D AArcCO_0090 tIF6; Translation initiation factor 6 (eIF-6) K03264 EIF6; translation initiation factor 6
C 03110 Chaperones and folding catalysts [BR:haaa03110]
D AArcCO_0269 groEL; Chaperonin GroEL, HSP60 family K22447 cct; archaeal chaperonin
D AArcCO_0177 gim5; putative prefoldin, molecular chaperone implicated in de novo protein folding K04797 pfdA; prefoldin alpha subunit
D AArcCO_0234 trxA; Thiol-disulfide isomerase or thioredoxin K03671 TXN; thioredoxin
D AArcCO_0283 trxA2; Thiol-disulfide isomerase or thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking
C 04121 Ubiquitin system [BR:haaa04121]
D AArcCO_0235 hypothetical protein K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 03051 Proteasome
C 03032 DNA replication proteins [BR:haaa03032]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
D AArcCO_0070 rnhA; Ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D AArcCO_0001 cdc6; Cdc6-related protein, AAA superfamily ATPase K10725 cdc6A; archaeal cell division control protein 6
D AArcCO_0028 mcm2; putative ATPase involved in replication control,Cdc46/Mcm family K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D AArcCO_0143 Archaeal DNA polymerase II, large subunit K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D AArcCO_0003 hys2; Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D AArcCO_0289 holB; ATPase involved in DNA replication HolB, large subunit K04800 rfcL; replication factor C large subunit
C 03036 Chromosome and associated proteins [BR:haaa03036]
D AArcCO_0164 hht1-2; Histones H3 and H4 K24450 hmf; DNA-binding protein
D AArcCO_0271 ftsZ; Cell division GTPase K03531 ftsZ; cell division protein FtsZ
D AArcCO_0009 flhG; FleN family ATPase involved in flagellar biosynthesis K03609 minD; septum site-determining protein MinD
D AArcCO_0023 flhG2; FleN family ATPase involved in flagellar biosynthesis K03609 minD; septum site-determining protein MinD
C 03400 DNA repair and recombination proteins [BR:haaa03400]
D AArcCO_0190 dinG; Rad3-related DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D AArcCO_0163 rpa1-2; ssDNA-binding replication factor A, large subunit K07466 RFA1; replication factor A1
D AArcCO_0107 nfo; Endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D AArcCO_0076 nfi; Deoxyinosine 3'endonuclease (endonuclease V) K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D AArcCO_0099 recJ; Single-stranded DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D AArcCO_0188 uvrC; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
D AArcCO_0181 mutS; Mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS
D AArcCO_0225 mutS2; DNA structure-specific ATPase involved in suppression of recombination, MutS family K07456 mutS2; DNA mismatch repair protein MutS2
D AArcCO_0130 Holliday junction resolvase, archaeal type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D AArcCO_0062 pol4; DNA polymerase IV (family X) K02347 polX; DNA polymerase (family X)
D AArcCO_0068 Protein, predicted to be involved in DNA repair K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:haaa03029]
D AArcCO_0175 tyrS; Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D AArcCO_0223 valS; Valyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D AArcCO_0123 argS; Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:haaa02000]
D AArcCO_0173 tbpA; ABC-type thiamine transport system, periplasmic component K02064 thiB; thiamine transport system substrate-binding protein
D AArcCO_0172 thiP; ABC-type Fe3+ transport system, permease component K02063 thiP; thiamine transport system permease protein
D AArcCO_0171 malK; ABC-type sugar transport system, ATPase component K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D AArcCO_0093 phnD; ABC-type phosphate/phosphonate transport system,periplasmic component K02044 phnD; phosphonate transport system substrate-binding protein
D AArcCO_0095 phnE; ABC-type phosphate/phosphonate transport system,permease component K02042 phnE; phosphonate transport system permease protein
D AArcCO_0094 phnC; ABC-type phosphate/phosphonate transport system,ATPase component K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D AArcCO_0120 ddpA; ABC-type transport system, periplasmic component K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D AArcCO_0277 ABC-2 family transporter K19341 nosY; Cu-processing system permease protein
D AArcCO_0278 ccmA2; ABC-type multidrug transport system, ATPase component K19340 nosF; Cu-processing system ATP-binding protein
D AArcCO_0279 Lipoprotein NosD family K07218 nosD; nitrous oxidase accessory protein
D AArcCO_0158 nosY; ABC-type transport system involved in multi-copper enzyme maturation, permease component K25147 berB; beta-exotoxin I transport system permease protein
D AArcCO_0159 nosY2; ABC-type transport system involved in multi-copper enzyme maturation, permease component K25147 berB; beta-exotoxin I transport system permease protein
D AArcCO_0157 ccmA; ABC-type multidrug transport system, ATPase component K25148 berA; beta-exotoxin I transport system ATP-binding protein
D AArcCO_0061 tlyC; Hemolysins-related protein containing CBS domains K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02044 Secretion system [BR:haaa02044]
D AArcCO_0056 ffh; Signal recognition particle GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D AArcCO_0178 ftsY; Signal recognition particle GTPase K03110 ftsY; fused signal recognition particle receptor
C 02042 Bacterial toxins [BR:haaa02042]
D AArcCO_0061 tlyC; Hemolysins-related protein containing CBS domains K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system
C 02035 Bacterial motility proteins
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:haaa04812]
D AArcCO_0271 ftsZ; Cell division GTPase K03531 ftsZ; cell division protein FtsZ
D AArcCO_0009 flhG; FleN family ATPase involved in flagellar biosynthesis K03609 minD; septum site-determining protein MinD
D AArcCO_0023 flhG2; FleN family ATPase involved in flagellar biosynthesis K03609 minD; septum site-determining protein MinD
C 04147 Exosome [BR:haaa04147]
D AArcCO_0276 Zn-dependent dipeptidase, microsomal dipeptidasehomolog K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D AArcCO_0141 sam1; S-adenosylhomocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D AArcCO_0047 argH; Argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D AArcCO_0048 argG; Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D AArcCO_0197 metC; Cystathionine beta-lyase/cystathionine gamma-synthase K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D AArcCO_0087 hemB; Delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D AArcCO_0218 fixA; Electron transfer flavoprotein, alpha and beta subunits K03522 fixB; electron transfer flavoprotein alpha subunit
C 02048 Prokaryotic defense system [BR:haaa02048]
D AArcCO_0272 CopG/MetJ, RHH domain containing DNA-binding protein, often an antitoxin in Type II toxin-antitoxin systems K07746 parD1_3_4; antitoxin ParD1/3/4
D AArcCO_0271 ftsZ; Cell division GTPase K03531 ftsZ; cell division protein FtsZ
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:haaa00537]
D AArcCO_0276 Zn-dependent dipeptidase, microsomal dipeptidasehomolog K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs
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A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D AArcCO_0307 curA; NADPH-dependent curcumin reductase CurA K00359 qorA; NADPH:quinone reductase [EC:1.6.5.5]
D AArcCO_0260 dPH5; Diphthamide biosynthesis methyltransferase K20215 dph5; diphthine synthase [EC:2.1.1.98]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D AArcCO_0290 fer; Ferredoxin K05337 fer; ferredoxin
D AArcCO_0219 fixA2; Electron transfer flavoprotein, beta subunit K03521 fixA; electron transfer flavoprotein beta subunit
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D AArcCO_0139 cspC; Cold shock protein, CspA family K03704 cspA; cold shock protein
D AArcCO_0220 cspC2; Cold shock protein, CspA family K03704 cspA; cold shock protein
C 99974 Translation
C 99975 Protein processing
C 99976 Replication and repair
D AArcCO_0110 putative endonuclease containing a URI domain K07461 K07461; putative endonuclease
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D AArcCO_0129 putative permease K07085 K07085; putative transport protein
C 99978 Cell growth
C 99993 Cell motility
C 99995 Signaling proteins
C 99992 Structural proteins
C 99994 Others
D AArcCO_0279 Lipoprotein NosD family K07218 nosD; nitrous oxidase accessory protein
B
B 09194 Poorly characterized
C 99996 General function prediction only
D AArcCO_0124 ATPase (PilT family) K06865 K06865; ATPase
D AArcCO_0240 putative metal-dependent hydrolase (urease superfamily) K07049 K07049; TatD-related deoxyribonuclease
C 99997 Function unknown
D AArcCO_0142 putative DNA-binding protein with PD1-like DNA-binding motif K06934 K06934; uncharacterized protein
D AArcCO_0267 putative permease K07089 K07089; uncharacterized protein
D AArcCO_0229 putative transporter component K07112 K07112; uncharacterized protein
D AArcCO_0230 putative transporter component K07112 K07112; uncharacterized protein
D AArcCO_0063 PIN-domain and Zn ribbon K09122 K09122; uncharacterized protein
D AArcCO_0116 Uncharacterized protein K09148 K09148; uncharacterized protein
D AArcCO_0186 putative nuclease of RNase H fold, RuvC/YqgF family K09150 K09150; uncharacterized protein
D AArcCO_0018 RPA family protein, a subunit of RPA complex in P.furiosus K09746 K09746; uncharacterized protein
D AArcCO_0224 putative secereted protein, contains kinase-interacting SIMPL domain K09807 K09807; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: September 21, 2024