+D	GENES	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a> &nbsp; KEGG Orthology (KO) - Halomicrobium mukohataei JP60 </h2>
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A09100 Metabolism
B
B  09101 Carbohydrate metabolism
C    00010 Glycolysis / Gluconeogenesis [PATH:halz00010]
D      E5139_15695 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_13425 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_09750 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      E5139_01835 class 1 fructose-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      E5139_00605 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_01830 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_02445 fructose-bisphosphate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      E5139_14980 tpiA; triose-phosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D      E5139_06445 gap; type I glyceraldehyde-3-phosphate dehydrogenase	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      E5139_05775 type II glyceraldehyde-3-phosphate dehydrogenase	K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D      E5139_05800 phosphoglycerate kinase	K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D      E5139_10595 2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D      E5139_00275 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      E5139_15690 pyk; pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      E5139_02260 ppsA; phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      E5139_06545 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      E5139_06550 alpha-ketoacid dehydrogenase subunit beta	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      E5139_06555 2-oxo acid dehydrogenase subunit E2	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      E5139_02680 2-oxoacid:acceptor oxidoreductase subunit alpha	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      E5139_02685 2-oxoacid:ferredoxin oxidoreductase subunit beta	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_14590 CoA-binding protein	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C    00020 Citrate cycle (TCA cycle) [PATH:halz00020]
D      E5139_07365 citrate synthase	K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D      E5139_10665 NADP-dependent isocitrate dehydrogenase	K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_02680 2-oxoacid:acceptor oxidoreductase subunit alpha	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      E5139_02685 2-oxoacid:ferredoxin oxidoreductase subunit beta	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      E5139_00865 sucD; succinate--CoA ligase subunit alpha	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      E5139_00870 sucC; ADP-forming succinate--CoA ligase subunit beta	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      E5139_13535 FAD-binding protein	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_10360 FAD-dependent oxidoreductase	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_13530 succinate dehydrogenase/fumarate reductase iron-sulfur subunit	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      E5139_13520 sdhC; succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      E5139_13525 succinate dehydrogenase	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      E5139_01185 class II fumarate hydratase	K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      E5139_06545 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      E5139_06550 alpha-ketoacid dehydrogenase subunit beta	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      E5139_06555 2-oxo acid dehydrogenase subunit E2	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C    00030 Pentose phosphate pathway [PATH:halz00030]
D      E5139_09750 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      E5139_06035 NAD(P)-dependent oxidoreductase	K19243 azf; NAD+ dependent glucose-6-phosphate dehydrogenase [EC:1.1.1.388]
D      E5139_00465 lactonase family protein	K07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31]
D      E5139_05320 6-phosphogluconate dehydrogenase	K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D      E5139_08845 rpiA; ribose-5-phosphate isomerase RpiA	K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D      E5139_10750 deoC; deoxyribose-phosphate aldolase	K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D      E5139_01005 phosphopentomutase/phosphoglucosamine mutase	K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_01120 carbohydrate kinase family protein	K26208 E2.7.1.239; alpha-D-ribose-1-phosphate 5-kinase (ATP) [EC:2.7.1.239]
D      E5139_01105 ribose 1,5-bisphosphate isomerase	K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D      E5139_07720 prs; ribose-phosphate diphosphokinase	K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D      E5139_09315 eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D      E5139_14495 glucose dehydrogenase	K22969 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D      E5139_15020 GMC family oxidoreductase	K19813 gdh; glucose dehydrogenase [EC:1.1.5.9]
D      E5139_14415 mandelate racemase/muconate lactonizing enzyme family protein	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      E5139_04890 mandelate racemase/muconate lactonizing enzyme family protein	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      E5139_15685 sugar kinase	K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D      E5139_05170 sugar kinase	K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D      E5139_15975 DUF4147 domain-containing protein	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      E5139_00605 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_01830 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_02445 fructose-bisphosphate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      E5139_01835 class 1 fructose-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
C    00040 Pentose and glucuronate interconversions [PATH:halz00040]
D      E5139_10655 cupin domain-containing protein	K26933 kdgF; unsaturated pyranuronate lyase [EC:4.2.99.25]
D      E5139_10305 UDP-glucose/GDP-mannose dehydrogenase family protein	K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D      E5139_04580 Gfo/Idh/MocA family oxidoreductase	K14273 xdh; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) [EC:1.1.1.179]
D      E5139_15810 Gfo/Idh/MocA family oxidoreductase	K24442 xacA; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) [EC:1.1.1.424]
C    00051 Fructose and mannose metabolism [PATH:halz00051]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_08285 mannose-1-phosphate guanylyltransferase	K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D      E5139_01835 class 1 fructose-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      E5139_00600 hypothetical protein	K27475 khk; ketohexokinase [EC:2.7.1.3]
D      E5139_00595 1-phosphofructokinase	K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]
D      E5139_00605 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_01830 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_02445 fructose-bisphosphate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      E5139_14980 tpiA; triose-phosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C    00052 Galactose metabolism [PATH:halz00052]
D      E5139_06595 NAD(P)-dependent oxidoreductase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      E5139_13320 NAD-dependent epimerase/dehydratase family protein	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_15695 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_13425 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_16015 DUF4981 domain-containing protein	K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D      E5139_03790 dgoD; galactonate dehydratase	K01684 dgoD; galactonate dehydratase [EC:4.2.1.6]
D      E5139_03890 dgoD; galactonate dehydratase	K01684 dgoD; galactonate dehydratase [EC:4.2.1.6]
D      E5139_03900 dgoD; galactonate dehydratase	K01684 dgoD; galactonate dehydratase [EC:4.2.1.6]
D      E5139_14415 mandelate racemase/muconate lactonizing enzyme family protein	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      E5139_04890 mandelate racemase/muconate lactonizing enzyme family protein	K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D      E5139_12810 sucrose-6-phosphate hydrolase	K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D      E5139_14445 alpha-glucosidase	K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]
D      E5139_03575 alpha-glucosidase	K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]
D      E5139_03580 alpha-glucosidase	K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]
C    00053 Ascorbate and aldarate metabolism [PATH:halz00053]
D      E5139_10305 UDP-glucose/GDP-mannose dehydrogenase family protein	K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00500 Starch and sucrose metabolism [PATH:halz00500]
D      E5139_12810 sucrose-6-phosphate hydrolase	K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D      E5139_12805 glycoside hydrolase family 68 protein	K00692 sacB; levansucrase [EC:2.4.1.10]
D      E5139_04340 glycoside hydrolase family 13 protein	K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]
D      E5139_14445 alpha-glucosidase	K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]
D      E5139_03575 alpha-glucosidase	K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]
D      E5139_03580 alpha-glucosidase	K01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]
D      E5139_04345 alpha-amylase	K00701 cgt; cyclomaltodextrin glucanotransferase [EC:2.4.1.19]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_15695 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_13425 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_09750 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C    00520 Amino sugar and nucleotide sugar metabolism [PATH:halz00520]
D      E5139_01885 PKD domain-containing protein	K01183 E3.2.1.14; chitinase [EC:3.2.1.14]
D      E5139_01890 PKD domain-containing protein	K01183 E3.2.1.14; chitinase [EC:3.2.1.14]
D      E5139_02975 PKD domain-containing protein	K01183 E3.2.1.14; chitinase [EC:3.2.1.14]
D      E5139_10600 lysozyme	K13381 chiA; bifunctional chitinase/lysozyme [EC:3.2.1.14 3.2.1.17]
D      E5139_03100 nagZ; beta-N-acetylhexosaminidase	K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D      E5139_10660 PKD domain-containing protein	K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
D      E5139_13335 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      E5139_11275 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      E5139_08830 glmM; phosphoglucosamine mutase	K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D      E5139_13460 glucose-1-phosphate thymidylyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D      E5139_03725 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D      E5139_03720 nucleotide sugar dehydrogenase	K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D      E5139_13270 nucleotide sugar dehydrogenase	K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D      E5139_13240 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	K13019 wbpI; UDP-GlcNAc3NAcA epimerase [EC:5.1.3.23]
D      E5139_10505 SDR family NAD(P)-dependent oxidoreductase	K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-]
D      E5139_10440 neuB; N-acetylneuraminate synthase	K18430 legI; N,N'-diacetyllegionaminate synthase [EC:2.5.1.101]
D      E5139_10485 acylneuraminate cytidylyltransferase family protein	K18431 legF; CMP-N,N'-diacetyllegionaminic acid synthase [EC:2.7.7.82]
D      E5139_15695 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_13425 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_10305 UDP-glucose/GDP-mannose dehydrogenase family protein	K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D      E5139_06595 NAD(P)-dependent oxidoreductase	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      E5139_13320 NAD-dependent epimerase/dehydratase family protein	K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D      E5139_09750 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      E5139_08285 mannose-1-phosphate guanylyltransferase	K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D      E5139_13305 DegT/DnrJ/EryC1/StrS aminotransferase family protein	K13010 per; perosamine synthetase [EC:2.6.1.102]
C    00620 Pyruvate metabolism [PATH:halz00620]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      E5139_02680 2-oxoacid:acceptor oxidoreductase subunit alpha	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      E5139_02685 2-oxoacid:ferredoxin oxidoreductase subunit beta	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      E5139_06545 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      E5139_06550 alpha-ketoacid dehydrogenase subunit beta	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      E5139_06555 2-oxo acid dehydrogenase subunit E2	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_15690 pyk; pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      E5139_00145 acetyl-CoA carboxylase biotin carboxylase subunit	K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D      E5139_15160 acylphosphatase	K01512 acyP; acylphosphatase [EC:3.6.1.7]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_14590 CoA-binding protein	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      E5139_08990 VOC family protein	K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D      E5139_12850 glyoxalase	K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D      E5139_15865 MBL fold metallo-hydrolase	K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D      E5139_09080 MBL fold metallo-hydrolase	K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D      E5139_11895 NADP-dependent malic enzyme	K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      E5139_01185 class II fumarate hydratase	K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D      E5139_15750 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      E5139_02260 ppsA; phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_00545 2-isopropylmalate synthase	K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C    00630 Glyoxylate and dicarboxylate metabolism [PATH:halz00630]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      E5139_07365 citrate synthase	K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_08095 MaoC family dehydratase	K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D      E5139_01715 mce; methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      E5139_02190 acyl dehydratase	K14449 mch; 2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
D      E5139_00145 acetyl-CoA carboxylase biotin carboxylase subunit	K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D      E5139_00135 acyl-CoA carboxylase subunit beta	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      E5139_14545 acyl-CoA carboxylase subunit beta	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      E5139_14550 hypothetical protein	K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D      E5139_01315 cobalamin B12-binding domain-containing protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      E5139_13970 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_01725 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_02180 methylaspartate mutase subunit E	K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D      E5139_02175 methylaspartate mutase subunit S	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      E5139_02185 methylaspartate ammonia-lyase	K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D      E5139_02170 CoA transferase	K19280 mct; succinyl-CoA:mesaconate CoA transferase [EC:2.8.3.26]
D      E5139_02195 citrate lyase subunit beta	K19281 mcl; beta-methylmalyl-CoA/(S)-malyl-CoA lyase [EC:4.1.3.24]
D      E5139_11175 HAD family hydrolase	K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D      E5139_13565 HAD family hydrolase	K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D      E5139_12065 HAD family hydrolase	K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D      E5139_12160 HAD-IIB family hydrolase	K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D      E5139_01130 rbcL; type III ribulose-bisphosphate carboxylase	K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D      E5139_02915 gltB; glutamate synthase large subunit	K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D      E5139_06725 glnA; type I glutamate--ammonia ligase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      E5139_01740 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_14215 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_12600 aminomethyl-transferring glycine dehydrogenase subunit GcvPA	K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D      E5139_12605 glycine dehydrogenase subunit 2	K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D      E5139_04625 aminomethyl transferase family protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_12585 gcvT; glycine cleavage system aminomethyltransferase GcvT	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_12590 gcvH; glycine cleavage system protein GcvH	K02437 gcvH; glycine cleavage system H protein
D      E5139_15975 DUF4147 domain-containing protein	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      E5139_09315 eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D      E5139_10260 formyltetrahydrofolate deformylase	K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
C    00640 Propanoate metabolism [PATH:halz00640]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_14590 CoA-binding protein	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      E5139_00145 acetyl-CoA carboxylase biotin carboxylase subunit	K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D      E5139_00135 acyl-CoA carboxylase subunit beta	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      E5139_14545 acyl-CoA carboxylase subunit beta	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      E5139_14550 hypothetical protein	K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D      E5139_14175 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      E5139_01715 mce; methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      E5139_01315 cobalamin B12-binding domain-containing protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      E5139_13970 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_01725 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_00870 sucC; ADP-forming succinate--CoA ligase subunit beta	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      E5139_00865 sucD; succinate--CoA ligase subunit alpha	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      E5139_04905 CoA-acylating methylmalonate-semialdehyde dehydrogenase	K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D      E5139_07365 citrate synthase	K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D      E5139_06125 methylglyoxal synthase	K01734 mgsA; methylglyoxal synthase [EC:4.2.3.3]
C    00650 Butanoate metabolism [PATH:halz00650]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_01825 3-hydroxybutyryl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      E5139_00680 3-hydroxyacyl-CoA dehydrogenase family protein	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      E5139_08095 MaoC family dehydratase	K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D      E5139_08115 phaC; class III poly(R)-hydroxyalkanoic acid synthase subunit PhaC	K03821 phaC; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaC [EC:2.3.1.304]
D      E5139_08110 poly(R)-hydroxyalkanoic acid synthase subunit	K22881 phaE; poly[(R)-3-hydroxyalkanoate] polymerase subunit PhaE
D      E5139_13535 FAD-binding protein	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_10360 FAD-dependent oxidoreductase	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_13530 succinate dehydrogenase/fumarate reductase iron-sulfur subunit	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      E5139_13520 sdhC; succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      E5139_13525 succinate dehydrogenase	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      E5139_14175 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      E5139_09800 succinate-semialdehyde dehydrogenase (NADP(+))	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      E5139_02680 2-oxoacid:acceptor oxidoreductase subunit alpha	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      E5139_02685 2-oxoacid:ferredoxin oxidoreductase subunit beta	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      E5139_11820 hydroxymethylglutaryl-CoA synthase family protein	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      E5139_04910 thiamine pyrophosphate-binding protein	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00550 ilvB; biosynthetic-type acetolactate synthase large subunit	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00555 ilvN; acetolactate synthase small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C    00660 C5-Branched dibasic acid metabolism [PATH:halz00660]
D      E5139_04910 thiamine pyrophosphate-binding protein	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00550 ilvB; biosynthetic-type acetolactate synthase large subunit	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00555 ilvN; acetolactate synthase small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D      E5139_00870 sucC; ADP-forming succinate--CoA ligase subunit beta	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      E5139_00865 sucD; succinate--CoA ligase subunit alpha	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      E5139_02185 methylaspartate ammonia-lyase	K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D      E5139_02180 methylaspartate mutase subunit E	K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D      E5139_02175 methylaspartate mutase subunit S	K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D      E5139_02195 citrate lyase subunit beta	K19281 mcl; beta-methylmalyl-CoA/(S)-malyl-CoA lyase [EC:4.1.3.24]
D      E5139_02190 acyl dehydratase	K14449 mch; 2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
D      E5139_03450 2-isopropylmalate synthase	K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D      E5139_00570 leuC; 3-isopropylmalate dehydratase large subunit	K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D      E5139_00575 leuD; 3-isopropylmalate dehydratase small subunit	K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D      E5139_00585 NAD-dependent isocitrate dehydrogenase	K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C    00562 Inositol phosphate metabolism [PATH:halz00562]
D      E5139_14245 inositol monophosphatase	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      E5139_03845 inositol monophosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      E5139_04885 sugar phosphate isomerase/epimerase	K03335 iolE; inosose dehydratase [EC:4.2.1.44]
D      E5139_04905 CoA-acylating methylmalonate-semialdehyde dehydrogenase	K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D      E5139_14980 tpiA; triose-phosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B  09102 Energy metabolism
C    00190 Oxidative phosphorylation [PATH:halz00190]
D      E5139_12700 NADH-quinone oxidoreductase subunit A	K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D      E5139_12705 NADH-quinone oxidoreductase subunit B	K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D      E5139_12710 NADH-quinone oxidoreductase subunit C	K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D      E5139_04235 NADH-quinone oxidoreductase subunit D	K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D      E5139_12715 NADH-quinone oxidoreductase subunit H	K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D      E5139_12720 NADH-quinone oxidoreductase subunit I	K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D      E5139_12725 hypothetical protein	K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D      E5139_12735 nuoK; NADH-quinone oxidoreductase subunit NuoK	K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D      E5139_12740 nuoL; NADH-quinone oxidoreductase subunit L	K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D      E5139_12750 NADH-quinone oxidoreductase subunit N	K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D      E5139_13750 NADH dehydrogenase FAD-containing subunit	K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D      E5139_00985 NAD(P)/FAD-dependent oxidoreductase	K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D      E5139_13535 FAD-binding protein	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_10360 FAD-dependent oxidoreductase	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_13530 succinate dehydrogenase/fumarate reductase iron-sulfur subunit	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      E5139_13520 sdhC; succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      E5139_13525 succinate dehydrogenase	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      E5139_01280 cyoE; protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
D      E5139_12905 heme-copper oxidase subunit III	K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D      E5139_02025 cytochrome-c oxidase	K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D      E5139_16715 b(o/a)3-type cytochrome-c oxidase subunit 1	K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D      E5139_12965 cytochrome-c oxidase	K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D      E5139_13990 cytochrome c oxidase subunit I	K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D      E5139_01275 coxB; cytochrome c oxidase subunit II	K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D      E5139_16720 cytochrome C oxidase subunit II	K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D      E5139_11905 cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      E5139_12550 cytochrome ubiquinol oxidase subunit I	K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D      E5139_12555 cytochrome d ubiquinol oxidase subunit II	K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D      E5139_09570 ATP synthase subunit A	K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D      E5139_09575 V-type ATP synthase subunit B	K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D      E5139_09560 V-type ATP synthase subunit C	K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D      E5139_09595 V-type ATP synthase subunit D	K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D      E5139_09555 V-type ATP synthase subunit E	K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D      E5139_09565 V-type ATP synthase subunit F	K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D      E5139_09540 ahaH; ATP synthase archaeal subunit H	K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D      E5139_09545 V-type ATP synthase subunit I	K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D      E5139_09550 hypothetical protein	K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D      E5139_02570 inorganic diphosphatase	K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D      E5139_12095 ppk1; polyphosphate kinase 1	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C    00195 Photosynthesis
C    00196 Photosynthesis - antenna proteins
C    00710 Carbon fixation by Calvin cycle [PATH:halz00710]
D      E5139_01130 rbcL; type III ribulose-bisphosphate carboxylase	K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D      E5139_05800 phosphoglycerate kinase	K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D      E5139_06445 gap; type I glyceraldehyde-3-phosphate dehydrogenase	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      E5139_05775 type II glyceraldehyde-3-phosphate dehydrogenase	K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D      E5139_00605 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_01830 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_01835 class 1 fructose-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      E5139_08845 rpiA; ribose-5-phosphate isomerase RpiA	K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D      E5139_14980 tpiA; triose-phosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D      E5139_15750 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      E5139_11895 NADP-dependent malic enzyme	K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C    00720 Other carbon fixation pathways [PATH:halz00720]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      E5139_02260 ppsA; phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      E5139_15750 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      E5139_01185 class II fumarate hydratase	K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D      E5139_13535 FAD-binding protein	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_10360 FAD-dependent oxidoreductase	K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D      E5139_13530 succinate dehydrogenase/fumarate reductase iron-sulfur subunit	K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D      E5139_13520 sdhC; succinate dehydrogenase, cytochrome b556 subunit	K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D      E5139_13525 succinate dehydrogenase	K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D      E5139_00865 sucD; succinate--CoA ligase subunit alpha	K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D      E5139_00870 sucC; ADP-forming succinate--CoA ligase subunit beta	K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D      E5139_13475 3-hydroxyacyl-CoA dehydrogenase	K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_02680 2-oxoacid:acceptor oxidoreductase subunit alpha	K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D      E5139_02685 2-oxoacid:ferredoxin oxidoreductase subunit beta	K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D      E5139_10665 NADP-dependent isocitrate dehydrogenase	K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D      E5139_02190 acyl dehydratase	K14449 mch; 2-methylfumaryl-CoA hydratase [EC:4.2.1.148]
D      E5139_01715 mce; methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      E5139_13970 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_01725 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_01315 cobalamin B12-binding domain-containing protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      E5139_14205 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C    00680 Methane metabolism [PATH:halz00680]
D      E5139_01740 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_14215 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_15975 DUF4147 domain-containing protein	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      E5139_00275 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      E5139_15750 phosphoenolpyruvate carboxylase	K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      E5139_00605 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_01830 aldolase	K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D      E5139_02445 fructose-bisphosphate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      E5139_01835 class 1 fructose-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      E5139_12200 methenyltetrahydromethanopterin cyclohydrolase	K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D      E5139_04990 5,10-methylenetetrahydromethanopterin reductase	K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D      E5139_02260 ppsA; phosphoenolpyruvate synthase	K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D      E5139_10595 2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D      E5139_07140 phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_04290 C-terminal binding protein	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_07270 serB; phosphoserine phosphatase SerB	K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D      E5139_10245 cofH; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofH	K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D      E5139_10230 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG	K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D      E5139_10225 cofC; 2-phospho-L-lactate guanylyltransferase	K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D      E5139_00175 2-phospho-L-lactate transferase	K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D      E5139_04995 coenzyme F420-0:L-glutamate ligase	K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D      E5139_02250 mfnA; tyrosine decarboxylase MfnA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C    00910 Nitrogen metabolism [PATH:halz00910]
D      E5139_15485 nitrate reductase	K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D      E5139_15480 respiratory nitrate reductase subunit beta	K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D      E5139_05435 ferredoxin--nitrite reductase	K00366 nirA; ferredoxin-nitrite reductase [EC:1.7.7.1]
D      E5139_08240 nirK; nitrite reductase, copper-containing	K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D      E5139_13015 cytochrome B	K04561 norB; nitric oxide reductase subunit B [EC:1.7.2.5]
D      E5139_02815 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_02910 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_16755 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_06725 glnA; type I glutamate--ammonia ligase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      E5139_02915 gltB; glutamate synthase large subunit	K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D      E5139_06395 carbonic anhydrase	K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C    00920 Sulfur metabolism [PATH:halz00920]
D      E5139_03910 recombination protein RecJ	K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D      E5139_02860 phosphoadenosine phosphosulfate reductase family protein	K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D      E5139_10925 twin-arginine translocation signal domain-containing protein	K21307 soeA; sulfite dehydrogenase (quinone) subunit SoeA [EC:1.8.5.6]
D      E5139_15440 DoxX family protein	K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D      E5139_05140 DoxX family protein	K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D      E5139_08890 sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      E5139_08895 sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      E5139_13505 cysE; serine O-acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      E5139_14685 PLP-dependent cysteine synthase family protein	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      E5139_09845 cysK; cysteine synthase A	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      E5139_08660 metX; homoserine O-acetyltransferase	K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D      E5139_16210 dimethyl sulfoxide reductase	K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D      E5139_16205 4Fe-4S dicluster domain-containing protein	K00184 dmsB; dimethyl sulfoxide reductase iron-sulfur subunit
D      E5139_16200 molybdopterin oxidoreductase	K00185 dmsC; dimethyl sulfoxide reductase membrane subunit
B
B  09103 Lipid metabolism
C    00061 Fatty acid biosynthesis [PATH:halz00061]
D      E5139_00145 acetyl-CoA carboxylase biotin carboxylase subunit	K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D      E5139_15800 3-oxoacyl-ACP synthase	K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D      E5139_08120 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_14540 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_08275 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_07860 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C    00062 Fatty acid elongation
C    00071 Fatty acid degradation [PATH:halz00071]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_06860 thiolase family protein	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D      E5139_13480 acyl-CoA dehydrogenase	K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D      E5139_08775 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00073 Cutin, suberine and wax biosynthesis
C    00074 Mycolic acid biosynthesis
C    00100 Steroid biosynthesis [PATH:halz00100]
D      E5139_07670 squalene/phytoene synthase	K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C    00120 Primary bile acid biosynthesis
C    00121 Secondary bile acid biosynthesis
C    00140 Steroid hormone biosynthesis
C    00561 Glycerolipid metabolism [PATH:halz00561]
D      E5139_15975 DUF4147 domain-containing protein	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_15710 glpK; glycerol kinase GlpK	K00864 glpK; glycerol kinase [EC:2.7.1.30]
D      E5139_11410 glycosyltransferase family 2 protein	K19003 mgdA; 1,2-diacylglycerol 3-beta-glucosyltransferase [EC:2.4.1.336]
D      E5139_13105 glycosyltransferase	K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
C    00564 Glycerophospholipid metabolism [PATH:halz00564]
D      E5139_00130 FAD-dependent oxidoreductase	K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D      E5139_15720 glpA; anaerobic glycerol-3-phosphate dehydrogenase subunit A	K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D      E5139_15725 glpB; glycerol-3-phosphate dehydrogenase subunit GlpB	K00112 glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
D      E5139_15730 anaerobic glycerol-3-phosphate dehydrogenase subunit C	K00113 glpC; glycerol-3-phosphate dehydrogenase subunit C
D      E5139_04925 glycerophosphodiester phosphodiesterase	K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D      E5139_02930 NAD(P)-dependent glycerol-1-phosphate dehydrogenase	K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D      E5139_02350 putative phosphoglycerol geranylgeranyltransferase	K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D      E5139_04750 heptaprenylglyceryl phosphate synthase	K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D      E5139_08705 CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase	K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D      E5139_15090 phosphatidylcholine/phosphatidylserine synthase	K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D      E5139_02700 NAD(P)/FAD-dependent oxidoreductase	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D      E5139_14170 NAD(P)/FAD-dependent oxidoreductase	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D      E5139_02875 geranylgeranyl reductase family protein	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
D      E5139_12890 NAD(P)/FAD-dependent oxidoreductase	K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C    00565 Ether lipid metabolism
C    00600 Sphingolipid metabolism [PATH:halz00600]
D      E5139_16015 DUF4981 domain-containing protein	K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D      E5139_10660 PKD domain-containing protein	K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C    00590 Arachidonic acid metabolism
C    00591 Linoleic acid metabolism
C    00592 alpha-Linolenic acid metabolism [PATH:halz00592]
D      E5139_06860 thiolase family protein	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C    01040 Biosynthesis of unsaturated fatty acids
B
B  09104 Nucleotide metabolism
C    00230 Purine metabolism [PATH:halz00230]
D      E5139_10380 NUDIX hydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      E5139_06170 NUDIX hydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      E5139_06175 NUDIX hydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      E5139_01005 phosphopentomutase/phosphoglucosamine mutase	K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_07720 prs; ribose-phosphate diphosphokinase	K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D      E5139_13620 purF; amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D      E5139_14715 purD; phosphoribosylamine--glycine ligase	K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D      E5139_03005 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D      E5139_12945 purL; phosphoribosylformylglycinamidine synthase subunit PurL	K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D      E5139_10280 purS; phosphoribosylformylglycinamidine synthase subunit PurS	K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D      E5139_10285 purQ; phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      E5139_01025 phosphoribosylformylglycinamidine cyclo-ligase	K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D      E5139_12685 5-(carboxyamino)imidazole ribonucleotide synthase	K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D      E5139_12695 purE; 5-(carboxyamino)imidazole ribonucleotide mutase	K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D      E5139_10255 phosphoribosylaminoimidazolesuccinocarboxamide synthase	K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D      E5139_03020 purB; adenylosuccinate lyase	K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D      E5139_07700 IMP cyclohydrolase	K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
D      E5139_01630 purine phosphoribosyltransferase family protein	K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D      E5139_14900 surE; 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      E5139_14915 guaB; IMP dehydrogenase	K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D      E5139_00395 nucleoside-diphosphate kinase	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D      E5139_09055 non-canonical purine NTP pyrophosphatase	K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D      E5139_08780 hypothetical protein	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      E5139_10130 guaA; glutamine-hydrolyzing GMP synthase subunit GuaA	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      E5139_03470 GMP synthase subunit A	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      E5139_10760 nucleoside phosphorylase	K26212 K26212; guanosine phosphorylase [EC:2.4.2.15]
D      E5139_11950 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      E5139_16610 ribonucleoside-diphosphate reductase subunit alpha	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      E5139_16615 ribonucleotide reductase	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      E5139_15840 ribonucleoside-diphosphate reductase	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      E5139_14660 cyaB; class IV adenylate cyclase	K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D      E5139_06635 adenylosuccinate synthase	K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D      E5139_14015 adenylosuccinate synthase	K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D      E5139_11805 adenylate kinase	K00939 adk; adenylate kinase [EC:2.7.4.3]
D      E5139_15000 adenylate kinase	K18532 AK6; adenylate kinase [EC:2.7.4.3]
D      E5139_03880 metallophosphoesterase	K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]
D      E5139_10690 HIT domain-containing protein	K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D      E5139_15970 DUF2437 domain-containing protein	K16856 ugl; ureidoglycolate lyase [EC:4.3.2.3]
C    00240 Pyrimidine metabolism [PATH:halz00240]
D      E5139_11280 carB; carbamoyl-phosphate synthase large subunit	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      E5139_10470 ATP-grasp domain-containing protein	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      E5139_10890 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D      E5139_14640 pyrB; aspartate carbamoyltransferase	K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D      E5139_14645 aspartate carbamoyltransferase regulatory subunit	K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D      E5139_04355 dihydroorotase	K01465 URA4; dihydroorotase [EC:3.5.2.3]
D      E5139_06485 quinone-dependent dihydroorotate dehydrogenase	K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D      E5139_07425 orotate phosphoribosyltransferase	K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D      E5139_12125 pyrF; orotidine-5'-phosphate decarboxylase	K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D      E5139_09630 UMP kinase	K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D      E5139_00395 nucleoside-diphosphate kinase	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D      E5139_10125 pyrG; CTP synthase (glutamine hydrolyzing)	K01937 pyrG; CTP synthase [EC:6.3.4.2]
D      E5139_11795 cytidylate kinase	K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D      E5139_09810 uridine kinase	K00876 udk; uridine kinase [EC:2.7.1.48]
D      E5139_14900 surE; 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      E5139_02395 HAD family hydrolase	K08723 yjjG; pyrimidine 5'-nucleotidase [EC:3.1.3.-]
D      E5139_00995 nucleoside phosphorylase	K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D      E5139_07555 upp; uracil phosphoribosyltransferase	K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D      E5139_01000 cdd; cytidine deaminase	K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D      E5139_03430 dCTP deaminase	K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D      E5139_11950 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      E5139_16610 ribonucleoside-diphosphate reductase subunit alpha	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      E5139_16615 ribonucleotide reductase	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      E5139_15840 ribonucleoside-diphosphate reductase	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      E5139_10210 dTMP kinase	K00943 tmk; dTMP kinase [EC:2.7.4.9]
D      E5139_06135 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D      E5139_02300 thyA; thymidylate synthase	K00560 thyA; thymidylate synthase [EC:2.1.1.45]
B
B  09105 Amino acid metabolism
C    00250 Alanine, aspartate and glutamate metabolism [PATH:halz00250]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_10615 FAD-dependent oxidoreductase	K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D      E5139_10670 asparaginase	K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D      E5139_13050 asparagine synthetase B	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      E5139_08050 alanine dehydrogenase	K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D      E5139_07030 argininosuccinate synthase	K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D      E5139_07035 argH; argininosuccinate lyase	K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D      E5139_06635 adenylosuccinate synthase	K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D      E5139_14015 adenylosuccinate synthase	K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D      E5139_03020 purB; adenylosuccinate lyase	K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D      E5139_14640 pyrB; aspartate carbamoyltransferase	K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D      E5139_14645 aspartate carbamoyltransferase regulatory subunit	K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D      E5139_14175 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      E5139_09800 succinate-semialdehyde dehydrogenase (NADP(+))	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D      E5139_02815 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_02910 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_16755 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_06725 glnA; type I glutamate--ammonia ligase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      E5139_11280 carB; carbamoyl-phosphate synthase large subunit	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      E5139_10470 ATP-grasp domain-containing protein	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      E5139_10890 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D      E5139_10285 purQ; phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      E5139_13335 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      E5139_11275 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      E5139_13620 purF; amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C    00260 Glycine, serine and threonine metabolism [PATH:halz00260]
D      E5139_06970 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      E5139_00080 asd; aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      E5139_05610 homoserine dehydrogenase	K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D      E5139_11340 homoserine kinase	K00872 thrB; homoserine kinase [EC:2.7.1.39]
D      E5139_07385 pyridoxal-phosphate dependent enzyme	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_15085 thrC; threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_07090 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_01700 pyridoxal-phosphate dependent enzyme	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_13400 low specificity L-threonine aldolase	K01620 ltaE; threonine aldolase [EC:4.1.2.48]
D      E5139_01740 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_14215 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_15975 DUF4147 domain-containing protein	K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D      E5139_10595 2,3-bisphosphoglycerate-independent phosphoglycerate mutase	K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D      E5139_07140 phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_04290 C-terminal binding protein	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_07270 serB; phosphoserine phosphatase SerB	K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D      E5139_12600 aminomethyl-transferring glycine dehydrogenase subunit GcvPA	K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D      E5139_12605 glycine dehydrogenase subunit 2	K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D      E5139_04625 aminomethyl transferase family protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_12585 gcvT; glycine cleavage system aminomethyltransferase GcvT	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_12590 gcvH; glycine cleavage system protein GcvH	K02437 gcvH; glycine cleavage system H protein
D      E5139_07345 threonine ammonia-lyase	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      E5139_16080 threonine/serine dehydratase	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      E5139_02450 tryptophan synthase subunit alpha	K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D      E5139_02455 trpB; tryptophan synthase subunit beta	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      E5139_06070 trpB; tryptophan synthase subunit beta	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      E5139_16515 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D      E5139_16520 aspartate aminotransferase family protein	K13745 ddc; L-2,4-diaminobutyrate decarboxylase [EC:4.1.1.86]
C    00270 Cysteine and methionine metabolism [PATH:halz00270]
D      E5139_13505 cysE; serine O-acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      E5139_14685 PLP-dependent cysteine synthase family protein	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      E5139_09845 cysK; cysteine synthase A	K01738 cysK; cysteine synthase [EC:2.5.1.47]
D      E5139_00625 methionine synthase	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      E5139_00630 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      E5139_14665 methionine adenosyltransferase	K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D      E5139_15275 spermidine synthase	K00797 speE; spermidine synthase [EC:2.5.1.16]
D      E5139_06950 amidohydrolase	K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D      E5139_13540 5'-deoxyadenosine deaminase	K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D      E5139_05510 DNA cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      E5139_06960 adenosylhomocysteinase	K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D      E5139_06970 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      E5139_00080 asd; aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      E5139_05610 homoserine dehydrogenase	K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D      E5139_11340 homoserine kinase	K00872 thrB; homoserine kinase [EC:2.7.1.39]
D      E5139_08660 metX; homoserine O-acetyltransferase	K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D      E5139_07260 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D      E5139_08655 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase	K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D      E5139_01920 aminodeoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_08720 branched-chain amino acid transaminase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_08890 sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      E5139_08895 sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      E5139_07185 malate dehydrogenase	K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D      E5139_07140 phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_04290 C-terminal binding protein	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C    00280 Valine, leucine and isoleucine degradation [PATH:halz00280]
D      E5139_01920 aminodeoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_08720 branched-chain amino acid transaminase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_13480 acyl-CoA dehydrogenase	K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D      E5139_06860 thiolase family protein	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D      E5139_00145 acetyl-CoA carboxylase biotin carboxylase subunit	K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D      E5139_00135 acyl-CoA carboxylase subunit beta	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      E5139_14545 acyl-CoA carboxylase subunit beta	K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D      E5139_14550 hypothetical protein	K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D      E5139_01715 mce; methylmalonyl-CoA epimerase	K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D      E5139_01315 cobalamin B12-binding domain-containing protein	K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D      E5139_13970 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_01725 methylmalonyl-CoA mutase	K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D      E5139_01095 NAD(P)-dependent oxidoreductase	K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D      E5139_04905 CoA-acylating methylmalonate-semialdehyde dehydrogenase	K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_11820 hydroxymethylglutaryl-CoA synthase family protein	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C    00290 Valine, leucine and isoleucine biosynthesis [PATH:halz00290]
D      E5139_07345 threonine ammonia-lyase	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      E5139_16080 threonine/serine dehydratase	K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D      E5139_03450 2-isopropylmalate synthase	K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D      E5139_00570 leuC; 3-isopropylmalate dehydratase large subunit	K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D      E5139_00575 leuD; 3-isopropylmalate dehydratase small subunit	K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D      E5139_00585 NAD-dependent isocitrate dehydrogenase	K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D      E5139_04910 thiamine pyrophosphate-binding protein	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00550 ilvB; biosynthetic-type acetolactate synthase large subunit	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00555 ilvN; acetolactate synthase small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D      E5139_00560 ilvC; ketol-acid reductoisomerase	K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D      E5139_09895 ilvD; dihydroxy-acid dehydratase	K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D      E5139_01920 aminodeoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_08720 branched-chain amino acid transaminase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_00545 2-isopropylmalate synthase	K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C    00300 Lysine biosynthesis [PATH:halz00300]
D      E5139_05610 homoserine dehydrogenase	K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D      E5139_06970 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      E5139_00080 asd; aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      E5139_03085 4-hydroxy-tetrahydrodipicolinate synthase	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      E5139_13725 dihydrodipicolinate synthase family protein	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      E5139_03080 dapB; 4-hydroxy-tetrahydrodipicolinate reductase	K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D      E5139_03070 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D      E5139_03055 M20 family metallopeptidase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D      E5139_03060 lysA; diaminopimelate decarboxylase	K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D      E5139_07040 lysW; lysine biosynthesis protein LysW	K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D      E5139_07055 acetylglutamate/acetylaminoadipate kinase	K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D      E5139_07050 N-acetyl-gamma-glutamyl-phosphate reductase	K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D      E5139_07060 aspartate aminotransferase family protein	K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D      E5139_07065 [LysW]-lysine hydrolase	K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C    00310 Lysine degradation [PATH:halz00310]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_08775 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_09800 succinate-semialdehyde dehydrogenase (NADP(+))	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00220 Arginine biosynthesis [PATH:halz00220]
D      E5139_07070 argF; ornithine carbamoyltransferase	K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D      E5139_07030 argininosuccinate synthase	K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D      E5139_07035 argH; argininosuccinate lyase	K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D      E5139_00970 rocF; arginase	K01476 rocF; arginase [EC:3.5.3.1]
D      E5139_10285 purQ; phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      E5139_06725 glnA; type I glutamate--ammonia ligase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      E5139_11280 carB; carbamoyl-phosphate synthase large subunit	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      E5139_10470 ATP-grasp domain-containing protein	K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D      E5139_10890 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D      E5139_02815 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_02910 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_16755 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_04730 M20 family peptidase	K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
D      E5139_07040 lysW; lysine biosynthesis protein LysW	K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D      E5139_07045 RimK family alpha-L-glutamate ligase	K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60]
D      E5139_07055 acetylglutamate/acetylaminoadipate kinase	K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D      E5139_07050 N-acetyl-gamma-glutamyl-phosphate reductase	K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D      E5139_07060 aspartate aminotransferase family protein	K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D      E5139_07065 [LysW]-lysine hydrolase	K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C    00330 Arginine and proline metabolism [PATH:halz00330]
D      E5139_07885 creatininase family protein	K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D      E5139_06055 creatininase family protein	K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D      E5139_03520 hydantoinase/oxoprolinase family protein	K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D      E5139_03515 hydantoinase B/oxoprolinase family protein	K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D      E5139_09705 pyruvoyl-dependent arginine decarboxylase	K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D      E5139_11145 agmatinase	K01480 speB; agmatinase [EC:3.5.3.11]
D      E5139_15275 spermidine synthase	K00797 speE; spermidine synthase [EC:2.5.1.16]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_02770 GNAT family N-acetyltransferase	K00657 speG; diamine N-acetyltransferase [EC:2.3.1.57]
D      E5139_00970 rocF; arginase	K01476 rocF; arginase [EC:3.5.3.1]
D      E5139_16815 proC; pyrroline-5-carboxylate reductase	K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D      E5139_08710 proline dehydrogenase	K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C    00340 Histidine metabolism [PATH:halz00340]
D      E5139_06940 ATP phosphoribosyltransferase	K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D      E5139_05880 hisE; phosphoribosyl-ATP diphosphatase	K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D      E5139_07450 hisI; phosphoribosyl-AMP cyclohydrolase	K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D      E5139_07475 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase	K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D      E5139_06760 hisH; imidazole glycerol phosphate synthase subunit HisH	K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D      E5139_12935 hisF; imidazole glycerol phosphate synthase subunit HisF	K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D      E5139_07490 hisB; imidazoleglycerol-phosphate dehydratase HisB	K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D      E5139_15005 histidinol-phosphate transaminase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      E5139_11840 histidinol-phosphatase	K04486 E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]
D      E5139_15380 hisD; histidinol dehydrogenase	K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00350 Tyrosine metabolism [PATH:halz00350]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_15005 histidinol-phosphate transaminase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      E5139_02250 mfnA; tyrosine decarboxylase MfnA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D      E5139_09800 succinate-semialdehyde dehydrogenase (NADP(+))	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C    00360 Phenylalanine metabolism [PATH:halz00360]
D      E5139_01825 3-hydroxybutyryl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      E5139_00680 3-hydroxyacyl-CoA dehydrogenase family protein	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_15005 histidinol-phosphate transaminase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      E5139_06885 katG; catalase/peroxidase HPI	K03782 katG; catalase-peroxidase [EC:1.11.1.21]
D      E5139_08090 alpha/beta hydrolase	K05714 mhpC; 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase [EC:3.7.1.14]
C    00380 Tryptophan metabolism [PATH:halz00380]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_08775 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_06885 katG; catalase/peroxidase HPI	K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C    00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:halz00400]
D      E5139_02445 fructose-bisphosphate aldolase	K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D      E5139_02440 3-dehydroquinate synthase II	K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D      E5139_02430 type I 3-dehydroquinate dehydratase	K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D      E5139_01940 shikimate dehydrogenase	K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D      E5139_14865 shikimate kinase	K00891 aroK; shikimate kinase [EC:2.7.1.71]
D      E5139_00490 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase	K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D      E5139_00485 aroC; chorismate synthase	K01736 aroC; chorismate synthase [EC:4.2.3.5]
D      E5139_01930 pabB; aminodeoxychorismate synthase, component I	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      E5139_11965 trpE; anthranilate synthase component I	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      E5139_01925 aminodeoxychorismate/anthranilate synthase component II	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      E5139_11960 aminodeoxychorismate/anthranilate synthase component II	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      E5139_11975 trpD; anthranilate phosphoribosyltransferase	K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D      E5139_11055 anthranilate phosphoribosyltransferase	K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D      E5139_11970 phosphoribosylanthranilate isomerase	K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D      E5139_02460 indole-3-glycerol-phosphate synthase	K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D      E5139_02450 tryptophan synthase subunit alpha	K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D      E5139_02455 trpB; tryptophan synthase subunit beta	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      E5139_06070 trpB; tryptophan synthase subunit beta	K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D      E5139_14870 chorismate mutase	K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D      E5139_14910 prephenate dehydrogenase	K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D      E5139_08075 pheA; prephenate dehydratase	K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_15005 histidinol-phosphate transaminase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B  09106 Metabolism of other amino acids
C    00410 beta-Alanine metabolism [PATH:halz00410]
D      E5139_02250 mfnA; tyrosine decarboxylase MfnA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D      E5139_14175 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D      E5139_03325 phosphopantothenate/pantothenate synthetase	K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D      E5139_04905 CoA-acylating methylmalonate-semialdehyde dehydrogenase	K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
C    00430 Taurine and hypotaurine metabolism [PATH:halz00430]
D      E5139_04745 ggt; gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      E5139_08050 alanine dehydrogenase	K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C    00440 Phosphonate and phosphinate metabolism
D      E5139_06850 MBL fold metallo-hydrolase	K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C    00450 Selenocompound metabolism [PATH:halz00450]
D      E5139_00625 methionine synthase	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      E5139_00630 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase	K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D      E5139_09385 cysteine desulfurase	K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D      E5139_15200 thioredoxin reductase	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      E5139_02800 NAD(P)/FAD-dependent oxidoreductase	K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D      E5139_02240 metG; methionine--tRNA ligase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C    00460 Cyanoamino acid metabolism [PATH:halz00460]
D      E5139_04745 ggt; gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      E5139_10670 asparaginase	K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D      E5139_01740 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_14215 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C    00470 D-Amino acid metabolism [PATH:halz00470]
D      E5139_10285 purQ; phosphoribosylformylglycinamidine synthase I	K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D      E5139_10050 DUF1611 domain-containing protein	K26272 dgcN; D-glutamate N-acetyltransferase [EC:2.3.1.312]
D      E5139_10055 dipeptide epimerase	K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
D      E5139_07865 N-acylamino acid racemase	K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
D      E5139_03060 lysA; diaminopimelate decarboxylase	K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C    00480 Glutathione metabolism [PATH:halz00480]
D      E5139_04745 ggt; gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D      E5139_11470 NAD(P)/FAD-dependent oxidoreductase	K03423 E1.8.1.13; bis-gamma-glutamylcystine reductase [EC:1.8.1.13]
D      E5139_10665 NADP-dependent isocitrate dehydrogenase	K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D      E5139_05320 6-phosphogluconate dehydrogenase	K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D      E5139_15275 spermidine synthase	K00797 speE; spermidine synthase [EC:2.5.1.16]
B
B  09107 Glycan biosynthesis and metabolism
C    00510 N-Glycan biosynthesis
C    00513 Various types of N-glycan biosynthesis
C    00512 Mucin type O-glycan biosynthesis
C    00515 Mannose type O-glycan biosynthesis
C    00514 Other types of O-glycan biosynthesis
C    00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C    00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C    00533 Glycosaminoglycan biosynthesis - keratan sulfate
C    00531 Glycosaminoglycan degradation
C    00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C    00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C    00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C    00604 Glycosphingolipid biosynthesis - ganglio series
C    00511 Other glycan degradation [PATH:halz00511]
D      E5139_16015 DUF4981 domain-containing protein	K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D      E5139_10660 PKD domain-containing protein	K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C    00540 Lipopolysaccharide biosynthesis
C    00542 O-Antigen repeat unit biosynthesis
C    00541 O-Antigen nucleotide sugar biosynthesis
C    00550 Peptidoglycan biosynthesis
C    00552 Teichoic acid biosynthesis [PATH:halz00552]
D      E5139_11255 undecaprenyl-diphosphate phosphatase	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C    00571 Lipoarabinomannan (LAM) biosynthesis
C    00572 Arabinogalactan biosynthesis - Mycobacterium
C    00543 Exopolysaccharide biosynthesis [PATH:halz00543]
D      E5139_13505 cysE; serine O-acetyltransferase	K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D      E5139_10415 sugar transferase	K13656 gumD; undecaprenyl-phosphate glucose phosphotransferase [EC:2.7.8.31]
B
B  09108 Metabolism of cofactors and vitamins
C    00730 Thiamine metabolism [PATH:halz00730]
D      E5139_14620 thiC; phosphomethylpyrimidine synthase ThiC	K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D      E5139_05105 thiD; bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D      E5139_14670 tRNA sulfurtransferase	K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D      E5139_03335 thiazole biosynthesis protein	K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D      E5139_05285 thiE; thiamine phosphate synthase	K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D      E5139_09645 thiL; thiamine-phosphate kinase	K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D      E5139_11805 adenylate kinase	K00939 adk; adenylate kinase [EC:2.7.4.3]
C    00740 Riboflavin metabolism [PATH:halz00740]
D      E5139_00445 GTP cyclohydrolase IIa	K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D      E5139_15210 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase	K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D      E5139_08735 ribB; 3,4-dihydroxy-2-butanone-4-phosphate synthase	K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D      E5139_12675 6,7-dimethyl-8-ribityllumazine synthase	K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D      E5139_05900 riboflavin synthase	K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D      E5139_08740 DUF120 domain-containing protein	K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D      E5139_12660 FAD synthase	K14656 ribL; FAD synthetase [EC:2.7.7.2]
D      E5139_10380 NUDIX hydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      E5139_06170 NUDIX hydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D      E5139_06175 NUDIX hydrolase	K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C    00750 Vitamin B6 metabolism [PATH:halz00750]
D      E5139_04610 aldo/keto reductase	K05275 E1.1.1.65; pyridoxine 4-dehydrogenase [EC:1.1.1.65]
D      E5139_07385 pyridoxal-phosphate dependent enzyme	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_15085 thrC; threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_07090 threonine synthase	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_01700 pyridoxal-phosphate dependent enzyme	K01733 thrC; threonine synthase [EC:4.2.3.1]
D      E5139_11365 pdxS; pyridoxal 5'-phosphate synthase lyase subunit PdxS	K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D      E5139_05890 pdxT; pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C    00760 Nicotinate and nicotinamide metabolism [PATH:halz00760]
D      E5139_10615 FAD-dependent oxidoreductase	K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D      E5139_10620 nadA; quinolinate synthase NadA	K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D      E5139_10610 nadC; carboxylating nicotinate-nucleotide diphosphorylase	K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D      E5139_04590 nicotinate phosphoribosyltransferase	K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D      E5139_14900 surE; 5'/3'-nucleotidase SurE	K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D      E5139_03230 nicotinamide-nucleotide adenylyltransferase	K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D      E5139_08980 NAD+ synthase	K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D      E5139_09015 nadE; NAD(+) synthase	K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D      E5139_02080 CinA family protein	K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D      E5139_00895 NAD-dependent protein deacylase	K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D      E5139_11435 NAD(+)/NADH kinase	K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D      E5139_02705 ATP-NAD kinase	K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D      E5139_09800 succinate-semialdehyde dehydrogenase (NADP(+))	K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C    00770 Pantothenate and CoA biosynthesis [PATH:halz00770]
D      E5139_04910 thiamine pyrophosphate-binding protein	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00550 ilvB; biosynthetic-type acetolactate synthase large subunit	K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D      E5139_00555 ilvN; acetolactate synthase small subunit	K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D      E5139_00560 ilvC; ketol-acid reductoisomerase	K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D      E5139_09895 ilvD; dihydroxy-acid dehydratase	K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D      E5139_13575 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase	K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D      E5139_08675 ketopantoate reductase family protein	K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D      E5139_03315 sugar kinase	K06982 pok; pantoate kinase [EC:2.7.1.169]
D      E5139_03325 phosphopantothenate/pantothenate synthetase	K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D      E5139_01555 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D      E5139_14345 phosphopantetheine adenylyltransferase	K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D      E5139_06810 DUF359 domain-containing protein	K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D      E5139_01920 aminodeoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_08720 branched-chain amino acid transaminase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_02250 mfnA; tyrosine decarboxylase MfnA	K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00780 Biotin metabolism [PATH:halz00780]
D      E5139_08120 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_14540 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_08275 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_07860 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_14605 8-amino-7-oxononanoate synthase	K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D      E5139_14600 bioD; dethiobiotin synthase	K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D      E5139_14610 transcriptional regulator	K25570 bioU; 8-amino-7-oxononanoate carboxylating dehydrogenase [EC:2.6.1.121]
D      E5139_14615 bioB; biotin synthase BioB	K01012 bioB; biotin synthase [EC:2.8.1.6]
D      E5139_00150 biotin--[acetyl-CoA-carboxylase] ligase	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C    00785 Lipoic acid metabolism [PATH:halz00785]
D      E5139_06535 lipA; lipoyl synthase	K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D      E5139_04350 lipoate--protein ligase family protein	K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D      E5139_04230 lipoate--protein ligase family protein	K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_06545 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D      E5139_06550 alpha-ketoacid dehydrogenase subunit beta	K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D      E5139_06555 2-oxo acid dehydrogenase subunit E2	K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D      E5139_12600 aminomethyl-transferring glycine dehydrogenase subunit GcvPA	K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D      E5139_12605 glycine dehydrogenase subunit 2	K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D      E5139_04625 aminomethyl transferase family protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_12585 gcvT; glycine cleavage system aminomethyltransferase GcvT	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_12590 gcvH; glycine cleavage system protein GcvH	K02437 gcvH; glycine cleavage system H protein
C    00790 Folate biosynthesis [PATH:halz00790]
D      E5139_06115 folE; GTP cyclohydrolase I FolE	K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D      E5139_01150 folP; dihydropteroate synthase	K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D      E5139_02970 folP; dihydropteroate synthase	K24102 folCP; dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
D      E5139_02305 dihydrofolate reductase	K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D      E5139_10590 dihydrofolate reductase	K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D      E5139_06105 6-pyruvoyl tetrahydropterin synthase family protein	K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D      E5139_11185 4a-hydroxytetrahydrobiopterin dehydratase	K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D      E5139_06110 7-carboxy-7-deazaguanine synthase QueE	K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D      E5139_06120 queC; 7-cyano-7-deazaguanine synthase QueC	K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D      E5139_11040 GTP cyclohydrolase I FolE2	K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D      E5139_06040 hypothetical protein	K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D      E5139_01145 DUF115 domain-containing protein	K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D      E5139_09900 GHMP kinase	K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D      E5139_10900 moaA; GTP 3',8-cyclase MoaA	K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D      E5139_15635 moaA; GTP 3',8-cyclase MoaA	K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D      E5139_07750 moaC; cyclic pyranopterin monophosphate synthase MoaC	K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D      E5139_07760 molybdopterin synthase	K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D      E5139_07745 molybdenum cofactor biosynthesis protein MoaB	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      E5139_10160 molybdopterin-binding protein	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      E5139_15640 molybdopterin molybdotransferase MoeA	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      E5139_15645 molybdopterin biosynthesis protein	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      E5139_11170 molybdopterin-binding protein	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      E5139_02100 molybdenum cofactor guanylyltransferase	K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C    00670 One carbon pool by folate [PATH:halz00670]
D      E5139_02305 dihydrofolate reductase	K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D      E5139_10590 dihydrofolate reductase	K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D      E5139_14205 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D      E5139_01740 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_14215 serine hydroxymethyltransferase	K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D      E5139_03005 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D      E5139_04625 aminomethyl transferase family protein	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_12585 gcvT; glycine cleavage system aminomethyltransferase GcvT	K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D      E5139_02300 thyA; thymidylate synthase	K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D      E5139_10260 formyltetrahydrofolate deformylase	K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D      E5139_11490 5-formyltetrahydrofolate cyclo-ligase	K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C    00830 Retinol metabolism
C    00860 Porphyrin metabolism [PATH:halz00860]
D      E5139_00330 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      E5139_11190 glutamyl-tRNA reductase	K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D      E5139_07735 glutamate-1-semialdehyde 2,1-aminomutase	K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D      E5139_07790 hemB; porphobilinogen synthase	K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D      E5139_08700 hemC; hydroxymethylbilane synthase	K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D      E5139_08690 uroporphyrinogen-III synthase	K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D      E5139_09425 heme-binding protein	K25033 chdC; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
D      E5139_08695 cobA; uroporphyrinogen-III C-methyltransferase	K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D      E5139_11195 bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase	K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D      E5139_11050 Lrp/AsnC family transcriptional regulator	K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D      E5139_11200 Lrp/AsnC family transcriptional regulator	K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D      E5139_13035 radical SAM/SPASM domain-containing protein	K22226 ahbC; Fe-coproporphyrin III synthase
D      E5139_11520 radical SAM protein	K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D      E5139_01280 cyoE; protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
D      E5139_11905 cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      E5139_14035 hypothetical protein	K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D      E5139_12450 ferredoxin	K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D      E5139_12485 cobalt-factor II C(20)-methyltransferase	K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D      E5139_12465 cobJ; precorrin-3B C(17)-methyltransferase	K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D      E5139_12470 cobalt-precorrin-2 C(20)-methyltransferase	K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D      E5139_12480 cobalt-precorrin-4/precorrin-4 C(11)-methyltransferase	K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D      E5139_12475 cbiG; cobalt-precorrin 5A hydrolase	K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D      E5139_12490 cbiT; precorrin-6Y C5,15-methyltransferase (decarboxylating) subunit CbiT	K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D      E5139_12405 cobalt-precorrin-7 (C(5))-methyltransferase	K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D      E5139_12410 precorrin isomerase	K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D      E5139_12395 cobyrinic acid a,c-diamide synthase	K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D      E5139_12415 cobN; cobaltochelatase subunit CobN	K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D      E5139_12635 cob(I)yrinic acid a,c-diamide adenosyltransferase	K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D      E5139_03985 cob(I)yrinic acid a,c-diamide adenosyltransferase	K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D      E5139_12390 cobyric acid synthase	K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D      E5139_04010 cobD; cobalamin biosynthesis protein CobD	K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D      E5139_03990 adenosylcobinamide amidohydrolase	K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90]
D      E5139_04000 cobalamin biosynthesis protein CobY	K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D      E5139_04005 cobS; adenosylcobinamide-GDP ribazoletransferase	K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D      E5139_03995 pyridoxal phosphate-dependent class II aminotransferase	K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D      E5139_12420 VWA domain-containing protein	K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1]
C    00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:halz00130]
D      E5139_03530 isochorismate synthase	K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D      E5139_15820 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase	K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D      E5139_14390 o-succinylbenzoate synthase	K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D      E5139_14385 acyl--CoA ligase	K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D      E5139_14405 1,4-dihydroxy-2-naphthoyl-CoA synthase	K01661 menB; naphthoate synthase [EC:4.1.3.36]
D      E5139_14395 1,4-dihydroxy-2-naphthoate polyprenyltransferase	K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B  09109 Metabolism of terpenoids and polyketides
C    00900 Terpenoid backbone biosynthesis [PATH:halz00900]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_11820 hydroxymethylglutaryl-CoA synthase family protein	K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D      E5139_10630 hmgA; hydroxymethylglutaryl-CoA reductase (NADPH)	K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D      E5139_00305 mvk; mevalonate kinase	K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D      E5139_13780 diphosphomevalonate decarboxylase	K17942 pmd; phosphomevalonate decarboxylase [EC:4.1.1.99]
D      E5139_00310 isopentenyl phosphate kinase family protein	K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D      E5139_10965 isopentenyl-diphosphate Delta-isomerase	K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D      E5139_00325 polyprenyl synthetase family protein	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      E5139_09505 polyprenyl synthetase family protein	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      E5139_10860 undecaprenyl diphosphate synthase family protein	K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D      E5139_10865 uppS; di-trans,poly-cis-decaprenylcistransferase	K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C    00902 Monoterpenoid biosynthesis
C    00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:halz00909]
D      E5139_07670 squalene/phytoene synthase	K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C    00904 Diterpenoid biosynthesis
C    00906 Carotenoid biosynthesis [PATH:halz00906]
D      E5139_04670 phytoene/squalene synthase family protein	K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D      E5139_09965 prenyltransferase	K20616 lyeJ; lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) [EC:2.5.1.150]
D      E5139_09960 crtI; phytoene desaturase	K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D      E5139_11545 crtI; phytoene desaturase	K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D      E5139_09970 carotenoid biosynthesis protein	K08977 cruF; bisanhydrobacterioruberin hydratase [EC:4.2.1.161]
D      E5139_09585 lycopene cyclase domain-containing protein	K22502 crtY; lycopene beta-cyclase [EC:5.5.1.19]
C    00905 Brassinosteroid biosynthesis
C    00981 Insect hormone biosynthesis
C    00908 Zeatin biosynthesis
C    00903 Limonene degradation
C    00907 Pinene, camphor and geraniol degradation [PATH:halz00907]
D      E5139_06860 thiolase family protein	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C    01052 Type I polyketide structures
C    00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C    01051 Biosynthesis of ansamycins
C    01059 Biosynthesis of enediyne antibiotics
D      E5139_11860 CRTAC1 family protein	K21162 sgcE4; enediyne biosynthesis protein E4
C    01056 Biosynthesis of type II polyketide backbone
C    01057 Biosynthesis of type II polyketide products
C    00253 Tetracycline biosynthesis
C    00523 Polyketide sugar unit biosynthesis [PATH:halz00523]
D      E5139_09245 glucose-1-phosphate thymidylyltransferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_01710 NDP-sugar synthase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_11270 nucleotidyl transferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_10310 sugar nucleotidyltransferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_13460 glucose-1-phosphate thymidylyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D      E5139_09260 rfbB; dTDP-glucose 4,6-dehydratase	K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D      E5139_09240 dTDP-4-dehydrorhamnose 3,5-epimerase	K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D      E5139_09255 rfbD; dTDP-4-dehydrorhamnose reductase	K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C    01054 Nonribosomal peptide structures
C    01053 Biosynthesis of siderophore group nonribosomal peptides
D      E5139_03530 isochorismate synthase	K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C    01055 Biosynthesis of vancomycin group antibiotics
D      E5139_09260 rfbB; dTDP-glucose 4,6-dehydratase	K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B  09110 Biosynthesis of other secondary metabolites
C    00940 Phenylpropanoid biosynthesis
C    00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C    00941 Flavonoid biosynthesis
C    00944 Flavone and flavonol biosynthesis
C    00942 Anthocyanin biosynthesis
C    00943 Isoflavonoid biosynthesis
C    00946 Degradation of flavonoids
C    00901 Indole alkaloid biosynthesis
C    00403 Indole diterpene alkaloid biosynthesis
C    00950 Isoquinoline alkaloid biosynthesis
C    00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C    00996 Biosynthesis of various alkaloids
C    00232 Caffeine metabolism
C    00965 Betalain biosynthesis
C    00966 Glucosinolate biosynthesis
C    00402 Benzoxazinoid biosynthesis
C    00311 Penicillin and cephalosporin biosynthesis
C    00332 Carbapenem biosynthesis
C    00261 Monobactam biosynthesis [PATH:halz00261]
D      E5139_06970 aspartate kinase	K00928 lysC; aspartate kinase [EC:2.7.2.4]
D      E5139_00080 asd; aspartate-semialdehyde dehydrogenase	K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D      E5139_03085 4-hydroxy-tetrahydrodipicolinate synthase	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      E5139_13725 dihydrodipicolinate synthase family protein	K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D      E5139_03080 dapB; 4-hydroxy-tetrahydrodipicolinate reductase	K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C    00331 Clavulanic acid biosynthesis
C    00521 Streptomycin biosynthesis [PATH:halz00521]
D      E5139_15695 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_13425 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_07440 glmM; phosphoglucosamine mutase	K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D      E5139_14245 inositol monophosphatase	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      E5139_03845 inositol monophosphatase family protein	K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D      E5139_09245 glucose-1-phosphate thymidylyltransferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_01710 NDP-sugar synthase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_11270 nucleotidyl transferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_10310 sugar nucleotidyltransferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_13460 glucose-1-phosphate thymidylyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D      E5139_09260 rfbB; dTDP-glucose 4,6-dehydratase	K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D      E5139_09240 dTDP-4-dehydrorhamnose 3,5-epimerase	K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D      E5139_09255 rfbD; dTDP-4-dehydrorhamnose reductase	K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C    00524 Neomycin, kanamycin and gentamicin biosynthesis
D      E5139_15695 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
D      E5139_13425 ROK family protein	K25026 glk; glucokinase [EC:2.7.1.2]
C    00525 Acarbose and validamycin biosynthesis [PATH:halz00525]
D      E5139_09245 glucose-1-phosphate thymidylyltransferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_01710 NDP-sugar synthase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_11270 nucleotidyl transferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_10310 sugar nucleotidyltransferase	K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D      E5139_13460 glucose-1-phosphate thymidylyltransferase	K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D      E5139_09260 rfbB; dTDP-glucose 4,6-dehydratase	K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C    00401 Novobiocin biosynthesis [PATH:halz00401]
D      E5139_14910 prephenate dehydrogenase	K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_15005 histidinol-phosphate transaminase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C    00404 Staurosporine biosynthesis
C    00405 Phenazine biosynthesis
D      E5139_01930 pabB; aminodeoxychorismate synthase, component I	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      E5139_11965 trpE; anthranilate synthase component I	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      E5139_01925 aminodeoxychorismate/anthranilate synthase component II	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      E5139_11960 aminodeoxychorismate/anthranilate synthase component II	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C    00333 Prodigiosin biosynthesis
D      E5139_08120 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_14540 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_08275 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_07860 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C    00254 Aflatoxin biosynthesis
C    00998 Biosynthesis of various antibiotics
C    00999 Biosynthesis of various plant secondary metabolites [PATH:halz00999]
D      E5139_14665 methionine adenosyltransferase	K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D      E5139_01940 shikimate dehydrogenase	K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C    00997 Biosynthesis of various other secondary metabolites
B
B  09111 Xenobiotics biodegradation and metabolism
C    00362 Benzoate degradation [PATH:halz00362]
D      E5139_08785 alpha/beta fold hydrolase	K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24]
D      E5139_06860 thiolase family protein	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D      E5139_08775 acyl-CoA dehydrogenase	K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D      E5139_01825 3-hydroxybutyryl-CoA dehydrogenase	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      E5139_00680 3-hydroxyacyl-CoA dehydrogenase family protein	K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C    00627 Aminobenzoate degradation
D      E5139_15160 acylphosphatase	K01512 acyP; acylphosphatase [EC:3.6.1.7]
C    00364 Fluorobenzoate degradation
C    00625 Chloroalkane and chloroalkene degradation [PATH:halz00625]
D      E5139_14845 aldehyde dehydrogenase family protein	K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C    00361 Chlorocyclohexane and chlorobenzene degradation
C    00623 Toluene degradation
C    00622 Xylene degradation
C    00633 Nitrotoluene degradation
D      E5139_13945 2-oxoacid:acceptor oxidoreductase subunit alpha	K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D      E5139_13950 2-ketoglutarate ferredoxin oxidoreductase subunit beta	K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C    00642 Ethylbenzene degradation
D      E5139_06860 thiolase family protein	K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C    00643 Styrene degradation
C    00791 Atrazine degradation
C    00930 Caprolactam degradation
C    00363 Bisphenol degradation
C    00621 Dioxin degradation
C    00626 Naphthalene degradation
C    00624 Polycyclic aromatic hydrocarbon degradation
C    00365 Furfural degradation
C    00984 Steroid degradation
C    00980 Metabolism of xenobiotics by cytochrome P450
C    00982 Drug metabolism - cytochrome P450
C    00983 Drug metabolism - other enzymes
B
B  09112 Not included in regular maps
C    09113 Global maps only
#
A09120 Genetic Information Processing
B
B  09121 Transcription
C    03020 RNA polymerase [PATH:halz03020]
D      E5139_05690 rpoB; DNA-directed RNA polymerase subunit B	K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D      E5139_05695 DNA-directed RNA polymerase subunit B''	K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D      E5139_05685 DNA-directed RNA polymerase subunit A'	K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D      E5139_05680 rpoA2; DNA-directed RNA polymerase subunit A''	K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D      E5139_00240 DNA-directed RNA polymerase subunit D	K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D      E5139_12920 DNA-directed RNA polymerase subunit L	K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D      E5139_06820 DNA-directed RNA polymerase	K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D      E5139_00655 RNA polymerase Rpb4 family protein	K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D      E5139_05700 DNA-directed RNA polymerase subunit H	K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D      E5139_00270 DNA-directed RNA polymerase subunit K	K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D      E5139_00265 DNA-directed RNA polymerase subunit N	K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D      E5139_03390 DNA-directed RNA polymerase subunit P	K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C    03022 Basal transcription factors [PATH:halz03022]
D      E5139_15190 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_02415 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_00685 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_08415 transcription initiation factor IIB family protein	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_13075 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_06785 TATA-box-binding protein	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      E5139_14785 transcription factor	K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D      E5139_02965 helicase	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      E5139_02150 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_07280 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C    03040 Spliceosome
B
B  09122 Translation
C    03010 Ribosome [PATH:halz03010]
D      E5139_00280 30S ribosomal protein S2	K02967 RP-S2; small subunit ribosomal protein S2
D      E5139_12290 30S ribosomal protein S3	K02982 RP-S3; small subunit ribosomal protein S3
D      E5139_00230 30S ribosomal protein S4	K02986 RP-S4; small subunit ribosomal protein S4
D      E5139_12360 30S ribosomal protein S5	K02988 RP-S5; small subunit ribosomal protein S5
D      E5139_05665 30S ribosomal protein S7	K02992 RP-S7; small subunit ribosomal protein S7
D      E5139_12335 30S ribosomal protein S8	K02994 RP-S8; small subunit ribosomal protein S8
D      E5139_00260 30S ribosomal protein S9	K02996 RP-S9; small subunit ribosomal protein S9
D      E5139_05600 30S ribosomal protein S10	K02946 RP-S10; small subunit ribosomal protein S10
D      E5139_02610 30S ribosomal protein S10	K02946 RP-S10; small subunit ribosomal protein S10
D      E5139_00235 30S ribosomal protein S11	K02948 RP-S11; small subunit ribosomal protein S11
D      E5139_05670 30S ribosomal protein S12	K02950 RP-S12; small subunit ribosomal protein S12
D      E5139_00225 30S ribosomal protein S13	K02952 RP-S13; small subunit ribosomal protein S13
D      E5139_12330 30S ribosomal protein S14	K02954 RP-S14; small subunit ribosomal protein S14
D      E5139_13810 30S ribosomal protein S15	K02956 RP-S15; small subunit ribosomal protein S15
D      E5139_12305 30S ribosomal protein S17	K02961 RP-S17; small subunit ribosomal protein S17
D      E5139_12280 30S ribosomal protein S19	K02965 RP-S19; small subunit ribosomal protein S19
D      E5139_13795 30S ribosomal protein S3ae	K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D      E5139_12320 30S ribosomal protein S4e	K02987 RP-S4e; small subunit ribosomal protein S4e
D      E5139_04565 30S ribosomal protein S6e	K02991 RP-S6e; small subunit ribosomal protein S6e
D      E5139_12105 30S ribosomal protein S8e	K02995 RP-S8e; small subunit ribosomal protein S8e
D      E5139_00195 30S ribosomal protein S17e	K02962 RP-S17e; small subunit ribosomal protein S17e
D      E5139_09655 30S ribosomal protein S19e	K02966 RP-S19e; small subunit ribosomal protein S19e
D      E5139_09030 rps24e; 30S ribosomal protein S24e	K02974 RP-S24e; small subunit ribosomal protein S24e
D      E5139_01675 30S ribosomal protein S27e	K02978 RP-S27e; small subunit ribosomal protein S27e
D      E5139_09035 30S ribosomal protein S27ae	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D      E5139_00385 30S ribosomal protein S28e	K02979 RP-S28e; small subunit ribosomal protein S28e
D      E5139_14070 50S ribosomal protein L1	K02863 RP-L1; large subunit ribosomal protein L1
D      E5139_12275 50S ribosomal protein L2	K02886 RP-L2; large subunit ribosomal protein L2
D      E5139_12260 50S ribosomal protein L3	K02906 RP-L3; large subunit ribosomal protein L3
D      E5139_12325 50S ribosomal protein L5	K02931 RP-L5; large subunit ribosomal protein L5
D      E5139_12340 50S ribosomal protein L6	K02933 RP-L6; large subunit ribosomal protein L6
D      E5139_14065 50S ribosomal protein L10	K02864 RP-L10; large subunit ribosomal protein L10
D      E5139_14075 50S ribosomal protein L11	K02867 RP-L11; large subunit ribosomal protein L11
D      E5139_14060 50S ribosomal protein P1	K02869 RP-L12; large subunit ribosomal protein L12
D      E5139_00255 50S ribosomal protein L13	K02871 RP-L13; large subunit ribosomal protein L13
D      E5139_12310 50S ribosomal protein L14	K02874 RP-L14; large subunit ribosomal protein L14
D      E5139_12370 50S ribosomal protein L15	K02876 RP-L15; large subunit ribosomal protein L15
D      E5139_12355 50S ribosomal protein L18	K02881 RP-L18; large subunit ribosomal protein L18
D      E5139_12285 50S ribosomal protein L22	K02890 RP-L22; large subunit ribosomal protein L22
D      E5139_12270 50S ribosomal protein L23	K02892 RP-L23; large subunit ribosomal protein L23
D      E5139_12315 50S ribosomal protein L24	K02895 RP-L24; large subunit ribosomal protein L24
D      E5139_12295 rpmC; 50S ribosomal protein L29	K02904 RP-L29; large subunit ribosomal protein L29
D      E5139_12365 rpmD; 50S ribosomal protein L30	K02907 RP-L30; large subunit ribosomal protein L30
D      E5139_12265 50S ribosomal protein L4	K02930 RP-L4e; large subunit ribosomal protein L4e
D      E5139_00380 50S ribosomal protein L7ae	K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D      E5139_06420 50S ribosomal protein L16	K02866 RP-L10e; large subunit ribosomal protein L10e
D      E5139_04675 50S ribosomal protein L15e	K02877 RP-L15e; large subunit ribosomal protein L15e
D      E5139_00250 50S ribosomal protein L18e	K02883 RP-L18e; large subunit ribosomal protein L18e
D      E5139_12350 50S ribosomal protein L19e	K02885 RP-L19e; large subunit ribosomal protein L19e
D      E5139_00660 50S ribosomal protein L21e	K02889 RP-L21e; large subunit ribosomal protein L21e
D      E5139_09340 50S ribosomal protein L31e	K02910 RP-L31e; large subunit ribosomal protein L31e
D      E5139_12345 50S ribosomal protein L32e	K02912 RP-L32e; large subunit ribosomal protein L32e
D      E5139_13625 50S ribosomal protein L37e	K02922 RP-L37e; large subunit ribosomal protein L37e
D      E5139_03395 50S ribosomal protein L37ae	K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D      E5139_09345 50S ribosomal protein L39e	K02924 RP-L39e; large subunit ribosomal protein L39e
D      E5139_06775 50S ribosomal protein L40e	K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D      E5139_01670 50S ribosomal protein L44e	K02929 RP-L44e; large subunit ribosomal protein L44e
D      E5139_09330 50S ribosomal protein L18a	K02944 RP-LX; large subunit ribosomal protein LX
D      E5139_16035 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_06470 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_13370 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_13375 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_06460 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_16030 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_13380 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_06455 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_16025 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
C    00970 Aminoacyl-tRNA biosynthesis [PATH:halz00970]
D      E5139_13845 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      E5139_06465 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      E5139_05595 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      E5139_07910 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_05980 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_00720 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_13155 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_05950 tRNA-Asn	K14220 tRNA-Asn; tRNA Asn
D      E5139_05705 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      E5139_05710 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      E5139_06450 tRNA-Cys	K14222 tRNA-Cys; tRNA Cys
D      E5139_01910 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      E5139_07685 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      E5139_13465 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      E5139_00015 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      E5139_12245 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      E5139_00100 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      E5139_06645 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      E5139_08315 tRNA-His	K14226 tRNA-His; tRNA His
D      E5139_11020 tRNA-Ile	K14227 tRNA-Ile; tRNA Ile
D      E5139_13550 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_11120 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_14255 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_00245 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_14355 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_05860 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      E5139_15060 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      E5139_01635 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      E5139_05945 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      E5139_06325 tRNA-Phe	K14231 tRNA-Phe; tRNA Phe
D      E5139_08350 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      E5139_11785 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      E5139_10410 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      E5139_00220 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_00460 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_03485 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_07360 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_08960 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      E5139_00430 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      E5139_12885 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      E5139_13545 tRNA-Trp	K14235 tRNA-Trp; tRNA Trp
D      E5139_04130 tRNA-Tyr	K14236 tRNA-Tyr; tRNA Tyr
D      E5139_11980 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      E5139_05365 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      E5139_12760 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      E5139_00330 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      E5139_13085 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D      E5139_02295 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D      E5139_13080 gatC; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D      E5139_11380 gatD; Glu-tRNA(Gln) amidotransferase subunit GatD	K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D      E5139_01175 gatE; Glu-tRNA(Gln) amidotransferase subunit GatE	K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D      E5139_08795 alanine--tRNA ligase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      E5139_02485 aspS; aspartate--tRNA(Asn) ligase	K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D      E5139_07150 glyS; glycine--tRNA ligase	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      E5139_10105 thrS; threonine--tRNA ligase	K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D      E5139_06900 serS; serine--tRNA ligase	K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D      E5139_14045 cysteine--tRNA ligase	K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D      E5139_02240 metG; methionine--tRNA ligase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D      E5139_10805 valine--tRNA ligase	K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D      E5139_07665 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_06585 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_08460 isoleucine--tRNA ligase	K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D      E5139_09625 lysine--tRNA ligase	K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D      E5139_09615 arginine--tRNA ligase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      E5139_02900 proline--tRNA ligase	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      E5139_09670 histidine--tRNA ligase	K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D      E5139_06495 phenylalanine--tRNA ligase subunit alpha	K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D      E5139_06490 phenylalanine--tRNA ligase subunit beta	K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D      E5139_00090 tyrosine--tRNA ligase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      E5139_06500 tryptophan--tRNA ligase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C    03013 Nucleocytoplasmic transport
C    03015 mRNA surveillance pathway
C    03008 Ribosome biogenesis in eukaryotes
B
B  09123 Folding, sorting and degradation
C    03060 Protein export [PATH:halz03060]
D      E5139_12375 secY; preprotein translocase subunit SecY	K03076 secY; preprotein translocase subunit SecY
D      E5139_09770 preprotein translocase subunit SecD	K03072 secD; preprotein translocase subunit SecD
D      E5139_09765 protein translocase subunit SecF	K03074 secF; preprotein translocase subunit SecF
D      E5139_09305 signal recognition particle protein	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D      E5139_13130 ffs; signal recognition particle sRNA	K01983 ffs; SRP RNA
D      E5139_09320 ftsY; signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      E5139_01965 protein translocase SEC61 complex subunit gamma	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D      E5139_01240 signal recognition particle protein Srp19	K03105 SRP19; signal recognition particle subunit SRP19
D      E5139_02130 ArsA family ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      E5139_16575 arsenic-transporting ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      E5139_00715 twin-arginine translocase TatA/TatE family subunit	K03116 tatA; sec-independent protein translocase protein TatA
D      E5139_08145 preprotein translocase subunit TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      E5139_08150 preprotein translocase subunit TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      E5139_10070 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      E5139_08060 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      E5139_07245 S26 family signal peptidase	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C    04141 Protein processing in endoplasmic reticulum
C    04130 SNARE interactions in vesicular transport
C    04120 Ubiquitin mediated proteolysis
C    04122 Sulfur relay system [PATH:halz04122]
D      E5139_08890 sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      E5139_08895 sulfurtransferase	K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D      E5139_16270 sulfurtransferase TusA family protein	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      E5139_16780 hypothetical protein	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      E5139_07760 molybdopterin synthase	K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D      E5139_10900 moaA; GTP 3',8-cyclase MoaA	K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D      E5139_15635 moaA; GTP 3',8-cyclase MoaA	K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D      E5139_11370 MoaD/ThiS family protein	K03636 moaD; sulfur-carrier protein
D      E5139_07750 moaC; cyclic pyranopterin monophosphate synthase MoaC	K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D      E5139_07745 molybdenum cofactor biosynthesis protein MoaB	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      E5139_10160 molybdopterin-binding protein	K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D      E5139_14670 tRNA sulfurtransferase	K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D      E5139_08875 MoaD/ThiS family protein	K03154 thiS; sulfur carrier protein
C    03050 Proteasome [PATH:halz03050]
D      E5139_01790 AAA family ATPase	K03420 psmR; proteasome regulatory subunit
D      E5139_09695 AAA family ATPase	K03420 psmR; proteasome regulatory subunit
D      E5139_15135 psmA; archaeal proteasome endopeptidase complex subunit alpha	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      E5139_03420 psmA; archaeal proteasome endopeptidase complex subunit alpha	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      E5139_03415 psmB; archaeal proteasome endopeptidase complex subunit beta	K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C    03018 RNA degradation [PATH:halz03018]
D      E5139_00275 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      E5139_04655 RNB domain-containing ribonuclease	K12573 rnr; ribonuclease R [EC:3.1.13.1]
D      E5139_00320 ribonuclease J	K12574 rnj; ribonuclease J [EC:3.1.-.-]
D      E5139_01505 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK
D      E5139_16085 grpE; nucleotide exchange factor GrpE	K04043 dnaK; molecular chaperone DnaK
D      E5139_12095 ppk1; polyphosphate kinase 1	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
B
B  09124 Replication and repair
C    03030 DNA replication [PATH:halz03030]
D      E5139_10845 DNA primase	K02316 dnaG; DNA primase [EC:2.7.7.101]
D      E5139_02585 ribonuclease HI family protein	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      E5139_01655 reverse transcriptase-like protein	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      E5139_09775 ribonuclease HII	K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D      E5139_08595 ligA; NAD-dependent DNA ligase LigA	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      E5139_01750 hypothetical protein	K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D      E5139_07250 DNA-directed DNA polymerase II small subunit	K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D      E5139_06995 DNA-directed DNA polymerase II large subunit	K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D      E5139_08380 AAA family ATPase	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      E5139_15545 priS; DNA primase small subunit PriS	K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D      E5139_08125 priL; DNA primase regulatory subunit PriL	K18882 priL; DNA primase large subunit
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
D      E5139_08235 DNA polymerase sliding clamp	K04802 PCNA; proliferating cell nuclear antigen
D      E5139_08805 replication factor C small subunit	K04801 rfcS; replication factor C small subunit
D      E5139_09410 AAA family ATPase	K04801 rfcS; replication factor C small subunit
D      E5139_11910 replication factor C large subunit	K04800 rfcL; replication factor C large subunit
D      E5139_13700 DUF2075 domain-containing protein	K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D      E5139_01190 flap endonuclease-1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      E5139_00920 ATP-dependent DNA ligase	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C    03410 Base excision repair [PATH:halz03410]
D      E5139_15165 8-oxoguanine DNA glycosylase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D      E5139_13195 endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      E5139_02625 endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      E5139_02760 nth; endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      E5139_05500 hypothetical protein	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D      E5139_14140 A/G-specific adenine glycosylase	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D      E5139_08235 DNA polymerase sliding clamp	K04802 PCNA; proliferating cell nuclear antigen
D      E5139_01190 flap endonuclease-1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      E5139_00920 ATP-dependent DNA ligase	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D      E5139_13490 DNA-3-methyladenine glycosylase 2 family protein	K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D      E5139_06765 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      E5139_00480 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      E5139_00125 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      E5139_04220 deoxyribonuclease IV	K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D      E5139_08475 DHH family phosphoesterase	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      E5139_08595 ligA; NAD-dependent DNA ligase LigA	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C    03420 Nucleotide excision repair [PATH:halz03420]
D      E5139_04875 uvrA; excinuclease ABC subunit UvrA	K03701 uvrA; excinuclease ABC subunit A
D      E5139_08930 uvrB; excinuclease ABC subunit UvrB	K03702 uvrB; excinuclease ABC subunit B
D      E5139_08535 excinuclease ABC subunit C	K03703 uvrC; excinuclease ABC subunit C
D      E5139_05920 ATP-dependent helicase	K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D      E5139_08595 ligA; NAD-dependent DNA ligase LigA	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      E5139_02965 helicase	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      E5139_02150 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_07280 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
D      E5139_08235 DNA polymerase sliding clamp	K04802 PCNA; proliferating cell nuclear antigen
D      E5139_00920 ATP-dependent DNA ligase	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C    03430 Mismatch repair [PATH:halz03430]
D      E5139_05075 mutS; DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      E5139_05115 mutS; DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      E5139_15285 DNA mismatch repair protein	K07456 mutS2; DNA mismatch repair protein MutS2
D      E5139_08190 endonuclease MutS2	K07456 mutS2; DNA mismatch repair protein MutS2
D      E5139_05165 mutL; DNA mismatch repair endonuclease MutL	K03572 mutL; DNA mismatch repair protein MutL
D      E5139_05920 ATP-dependent helicase	K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D      E5139_08475 DHH family phosphoesterase	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      E5139_08595 ligA; NAD-dependent DNA ligase LigA	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      E5139_05585 DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      E5139_08235 DNA polymerase sliding clamp	K04802 PCNA; proliferating cell nuclear antigen
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
D      E5139_00920 ATP-dependent DNA ligase	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C    03440 Homologous recombination [PATH:halz03440]
D      E5139_08475 DHH family phosphoesterase	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      E5139_06945 hypothetical protein	K04067 priC; primosomal replication protein N''
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
C    03450 Non-homologous end-joining
D      E5139_01190 flap endonuclease-1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C    03460 Fanconi anemia pathway
B
B  09126 Chromosome
C    03082 ATP-dependent chromatin remodeling
C    03083 Polycomb repressive complex
B
B  09125 Information processing in viruses
C    03230 Viral genome structure
C    03240 Viral replication
C    03250 Viral life cycle - HIV-1 [PATH:halz03250]
D      E5139_11080 peptidylprolyl isomerase	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      E5139_06815 DNA-directed RNA polymerase, subunit E''	K15171 SUPT4H1; transcription elongation factor SPT4
D      E5139_01970 transcription elongation factor Spt5	K15172 SUPT5H; transcription elongation factor SPT5
C    03260 Virion - Human immunodeficiency virus
C    03271 Virion - Rotavirus
C    03262 Virion - Coronavirus
C    03261 Virion - Influenza virus
C    03263 Virion - Enterovirus
C    03264 Virion - Flavivirus
C    03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C    03272 Virion - Hepatitis viruses
C    03266 Virion - Herpesvirus
C    03268 Virion - Orthopoxvirus
C    03267 Virion - Adenovirus
C    03259 Virion - Bacteriophages T4 and T7
C    03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B  09131 Membrane transport
C    02010 ABC transporters [PATH:halz02010]
D      E5139_10185 sulfate ABC transporter substrate-binding protein	K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D      E5139_10180 ABC transporter permease subunit	K15496 wtpB; molybdate/tungstate transport system permease protein
D      E5139_10175 ABC transporter ATP-binding protein	K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D      E5139_14530 extracellular solute-binding protein	K02012 afuA; iron(III) transport system substrate-binding protein
D      E5139_14525 iron ABC transporter permease	K02011 afuB; iron(III) transport system permease protein
D      E5139_14520 ABC transporter ATP-binding protein	K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D      E5139_12780 thiamine ABC transporter substrate-binding protein	K02064 thiB; thiamine transport system substrate-binding protein
D      E5139_12785 iron ABC transporter permease	K02063 thiP; thiamine transport system permease protein
D      E5139_12790 ABC transporter ATP-binding protein	K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D      E5139_14480 ABC transporter ATP-binding protein	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_07890 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_12220 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_16010 ABC transporter ATP-binding protein	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_04330 ABC transporter ATP-binding protein	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_04325 extracellular solute-binding protein	K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D      E5139_04320 sugar ABC transporter permease	K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D      E5139_04315 ABC transporter permease subunit	K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D      E5139_15995 extracellular solute-binding protein	K10188 lacE; lactose/L-arabinose transport system substrate-binding protein
D      E5139_16000 sugar ABC transporter permease	K10189 lacF; lactose/L-arabinose transport system permease protein
D      E5139_16005 carbohydrate ABC transporter permease	K10190 lacG; lactose/L-arabinose transport system permease protein
D      E5139_14465 extracellular solute-binding protein	K10236 thuE; trehalose/maltose transport system substrate-binding protein
D      E5139_14470 sugar ABC transporter permease	K10237 thuF; trehalose/maltose transport system permease protein
D      E5139_14475 carbohydrate ABC transporter permease	K10238 thuG; trehalose/maltose transport system permease protein
D      E5139_08250 BMP family ABC transporter substrate-binding protein	K07335 bmpA; basic membrane protein A and related proteins
D      E5139_03105 BMP family ABC transporter substrate-binding protein	K07335 bmpA; basic membrane protein A and related proteins
D      E5139_03115 ABC transporter permease	K23535 nupB; general nucleoside transport system permease protein
D      E5139_03120 ABC transporter permease	K23536 nupC; general nucleoside transport system permease protein
D      E5139_03110 ABC transporter ATP-binding protein	K23537 nupA; general nucleoside transport system ATP-binding protein
D      E5139_00140 extracellular solute-binding protein	K17315 gtsA; glucose/mannose transport system substrate-binding protein
D      E5139_12235 carbohydrate ABC transporter substrate-binding protein	K17315 gtsA; glucose/mannose transport system substrate-binding protein
D      E5139_12230 sugar ABC transporter permease	K17316 gtsB; glucose/mannose transport system permease protein
D      E5139_12225 carbohydrate ABC transporter permease	K17317 gtsC; glucose/mannose transport system permease protein
D      E5139_04945 ABC transporter substrate-binding protein	K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
D      E5139_04940 sugar ABC transporter permease	K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein
D      E5139_04935 carbohydrate ABC transporter permease	K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein
D      E5139_04930 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10]
D      E5139_12085 PstS family phosphate ABC transporter substrate-binding protein	K02040 pstS; phosphate transport system substrate-binding protein
D      E5139_05070 PstS family phosphate ABC transporter substrate-binding protein	K02040 pstS; phosphate transport system substrate-binding protein
D      E5139_12080 pstC; phosphate ABC transporter permease subunit PstC	K02037 pstC; phosphate transport system permease protein
D      E5139_05065 pstC; phosphate ABC transporter permease subunit PstC	K02037 pstC; phosphate transport system permease protein
D      E5139_12075 pstA; phosphate ABC transporter permease PstA	K02038 pstA; phosphate transport system permease protein
D      E5139_05060 pstA; phosphate ABC transporter permease PstA	K02038 pstA; phosphate transport system permease protein
D      E5139_12070 pstB; phosphate ABC transporter ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      E5139_05055 phosphate ABC transporter ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      E5139_15775 ABC transporter substrate-binding protein	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      E5139_15790 branched-chain amino acid ABC transporter permease	K01997 livH; branched-chain amino acid transport system permease protein
D      E5139_15795 branched-chain amino acid ABC transporter permease	K01998 livM; branched-chain amino acid transport system permease protein
D      E5139_15780 ABC transporter ATP-binding protein	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      E5139_15785 ABC transporter ATP-binding protein	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      E5139_16440 zinc ABC transporter substrate-binding protein	K09815 znuA; zinc transport system substrate-binding protein
D      E5139_08215 zinc ABC transporter substrate-binding protein	K09815 znuA; zinc transport system substrate-binding protein
D      E5139_16450 metal ABC transporter permease	K09816 znuB; zinc transport system permease protein
D      E5139_08205 metal ABC transporter permease	K09816 znuB; zinc transport system permease protein
D      E5139_16445 metal ABC transporter ATP-binding protein	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      E5139_08210 metal ABC transporter ATP-binding protein	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      E5139_04770 metal transporter	K02009 cbiN; cobalt/nickel transport protein
D      E5139_04775 metal transporter	K02007 cbiM; cobalt/nickel transport system permease protein
D      E5139_04765 cbiQ; cobalt ECF transporter T component CbiQ	K02008 cbiQ; cobalt/nickel transport system permease protein
D      E5139_04760 energy-coupling factor ABC transporter ATP-binding protein	K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D      E5139_05660 BioY family transporter	K03523 bioY; biotin transport system substrate-specific component
D      E5139_05650 energy-coupling factor transporter transmembrane protein EcfT	K16783 bioN; biotin transport system permease protein
D      E5139_05655 ABC transporter ATP-binding protein	K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D      E5139_05030 hypothetical protein	K19341 nosY; Cu-processing system permease protein
D      E5139_05040 copper-binding protein	K07218 nosD; nitrous oxidase accessory protein
D      E5139_05035 ABC transporter ATP-binding protein	K19340 nosF; Cu-processing system ATP-binding protein
D      E5139_10430 ABC transporter ATP-binding protein	K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
C    02060 Phosphotransferase system (PTS)
D      E5139_00595 1-phosphofructokinase	K00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]
C    03070 Bacterial secretion system [PATH:halz03070]
D      E5139_09770 preprotein translocase subunit SecD	K03072 secD; preprotein translocase subunit SecD
D      E5139_09765 protein translocase subunit SecF	K03074 secF; preprotein translocase subunit SecF
D      E5139_12375 secY; preprotein translocase subunit SecY	K03076 secY; preprotein translocase subunit SecY
D      E5139_09320 ftsY; signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      E5139_09305 signal recognition particle protein	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D      E5139_00715 twin-arginine translocase TatA/TatE family subunit	K03116 tatA; sec-independent protein translocase protein TatA
D      E5139_08145 preprotein translocase subunit TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      E5139_08150 preprotein translocase subunit TatC	K03118 tatC; sec-independent protein translocase protein TatC
B
B  09132 Signal transduction
C    02020 Two-component system [PATH:halz02020]
D      E5139_12085 PstS family phosphate ABC transporter substrate-binding protein	K02040 pstS; phosphate transport system substrate-binding protein
D      E5139_05070 PstS family phosphate ABC transporter substrate-binding protein	K02040 pstS; phosphate transport system substrate-binding protein
D      E5139_15555 PDZ domain-containing protein	K04771 degP; serine protease Do [EC:3.4.21.107]
D      E5139_06285 histidine kinase	K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
D      E5139_11905 cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
D      E5139_12805 glycoside hydrolase family 68 protein	K00692 sacB; levansucrase [EC:2.4.1.10]
D      E5139_02820 CoA ester lyase	K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D      E5139_00185 triphosphoribosyl-dephospho-CoA synthase	K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D      E5139_15485 nitrate reductase	K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D      E5139_15480 respiratory nitrate reductase subunit beta	K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D      E5139_07775 P-II family nitrogen regulator	K04751 glnB; nitrogen regulatory protein P-II 1
D      E5139_06725 glnA; type I glutamate--ammonia ligase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_04540 protein-glutamate O-methyltransferase CheR	K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D      E5139_15715 extracellular solute-binding protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_15245 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_02420 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_15430 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11295 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11325 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_02805 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11900 PAS domain-containing protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_08245 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_04690 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_00695 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_14420 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_08610 HAMP domain-containing protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_04525 purine-binding chemotaxis protein CheW	K03408 cheW; purine-binding chemotaxis protein CheW
D      E5139_04535 chemotaxis protein CheA	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      E5139_04475 response regulator	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      E5139_04530 chemotaxis response regulator protein-glutamate methylesterase	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      E5139_12550 cytochrome ubiquinol oxidase subunit I	K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D      E5139_12555 cytochrome d ubiquinol oxidase subunit II	K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D      E5139_03725 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D      E5139_03720 nucleotide sugar dehydrogenase	K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D      E5139_13270 nucleotide sugar dehydrogenase	K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
C    04010 MAPK signaling pathway
C    04013 MAPK signaling pathway - fly
C    04016 MAPK signaling pathway - plant
C    04011 MAPK signaling pathway - yeast
C    04012 ErbB signaling pathway
C    04014 Ras signaling pathway
C    04015 Rap1 signaling pathway
C    04310 Wnt signaling pathway
C    04330 Notch signaling pathway
C    04340 Hedgehog signaling pathway
C    04341 Hedgehog signaling pathway - fly
C    04350 TGF-beta signaling pathway
C    04390 Hippo signaling pathway
C    04391 Hippo signaling pathway - fly
C    04392 Hippo signaling pathway - multiple species
C    04370 VEGF signaling pathway
C    04371 Apelin signaling pathway
C    04630 JAK-STAT signaling pathway
C    04064 NF-kappa B signaling pathway
C    04668 TNF signaling pathway
C    04066 HIF-1 signaling pathway
C    04068 FoxO signaling pathway
C    04020 Calcium signaling pathway
C    04070 Phosphatidylinositol signaling system
C    04072 Phospholipase D signaling pathway
C    04071 Sphingolipid signaling pathway
C    04024 cAMP signaling pathway
C    04022 cGMP-PKG signaling pathway
C    04151 PI3K-Akt signaling pathway
C    04152 AMPK signaling pathway
C    04150 mTOR signaling pathway
C    04075 Plant hormone signal transduction
B
B  09133 Signaling molecules and interaction
C    04080 Neuroactive ligand-receptor interaction
C    04060 Cytokine-cytokine receptor interaction
C    04061 Viral protein interaction with cytokine and cytokine receptor
C    04512 ECM-receptor interaction
C    04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B  09141 Transport and catabolism
C    04144 Endocytosis
C    04145 Phagosome
C    04142 Lysosome
C    04146 Peroxisome
C    04140 Autophagy - animal
C    04138 Autophagy - yeast
C    04136 Autophagy - other
C    04137 Mitophagy - animal
C    04139 Mitophagy - yeast
C    04148 Efferocytosis
D      E5139_00970 rocF; arginase	K01476 rocF; arginase [EC:3.5.3.1]
B
B  09143 Cell growth and death
C    04110 Cell cycle
C    04111 Cell cycle - yeast
C    04112 Cell cycle - Caulobacter
C    04113 Meiosis - yeast
C    04114 Oocyte meiosis
C    04210 Apoptosis
C    04214 Apoptosis - fly
C    04215 Apoptosis - multiple species
C    04216 Ferroptosis
C    04217 Necroptosis
C    04115 p53 signaling pathway
C    04218 Cellular senescence
B
B  09144 Cellular community - eukaryotes
C    04510 Focal adhesion
C    04520 Adherens junction
C    04530 Tight junction
C    04540 Gap junction
C    04550 Signaling pathways regulating pluripotency of stem cells
B
B  09145 Cellular community - prokaryotes
C    02024 Quorum sensing [PATH:halz02024]
D      E5139_01930 pabB; aminodeoxychorismate synthase, component I	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      E5139_11965 trpE; anthranilate synthase component I	K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D      E5139_01925 aminodeoxychorismate/anthranilate synthase component II	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      E5139_11960 aminodeoxychorismate/anthranilate synthase component II	K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D      E5139_15890 extracellular solute-binding protein	K02055 ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein
D      E5139_15895 ABC transporter permease subunit	K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D      E5139_15900 ABC transporter permease subunit	K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D      E5139_15905 ABC transporter ATP-binding protein	K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D      E5139_15775 ABC transporter substrate-binding protein	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      E5139_15790 branched-chain amino acid ABC transporter permease	K01997 livH; branched-chain amino acid transport system permease protein
D      E5139_15795 branched-chain amino acid ABC transporter permease	K01998 livM; branched-chain amino acid transport system permease protein
D      E5139_15780 ABC transporter ATP-binding protein	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      E5139_15785 ABC transporter ATP-binding protein	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      E5139_04380 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_11115 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_09120 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_03570 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_03870 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_04375 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_11110 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_09125 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_03565 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_05830 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_03865 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_04370 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_11105 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_09130 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_03560 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_05825 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_03860 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_04385 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_11100 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_09135 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_03555 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_05820 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_03855 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_05815 ATP-binding cassette domain-containing protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      E5139_01495 PKD domain-containing protein	K14645 K14645; serine protease [EC:3.4.21.-]
D      E5139_00980 peptidase S8/S53 subtilisin kexin sedolisin	K14645 K14645; serine protease [EC:3.4.21.-]
D      E5139_12375 secY; preprotein translocase subunit SecY	K03076 secY; preprotein translocase subunit SecY
D      E5139_09320 ftsY; signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      E5139_09305 signal recognition particle protein	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C    05111 Biofilm formation - Vibrio cholerae
C    02025 Biofilm formation - Pseudomonas aeruginosa
C    02026 Biofilm formation - Escherichia coli
B
B  09142 Cell motility
C    02030 Bacterial chemotaxis [PATH:halz02030]
D      E5139_15715 extracellular solute-binding protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_15245 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_02420 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_15430 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11295 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11325 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_02805 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11900 PAS domain-containing protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_08245 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_04690 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_00695 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_14420 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_08610 HAMP domain-containing protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_04535 chemotaxis protein CheA	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      E5139_04525 purine-binding chemotaxis protein CheW	K03408 cheW; purine-binding chemotaxis protein CheW
D      E5139_04475 response regulator	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      E5139_04470 chemotaxis protein CheA	K03410 cheC; chemotaxis protein CheC
D      E5139_07765 chemotaxis protein CheC	K03410 cheC; chemotaxis protein CheC
D      E5139_13925 chemotaxis protein CheC	K03410 cheC; chemotaxis protein CheC
D      E5139_15010 chemotaxis protein CheC	K03410 cheC; chemotaxis protein CheC
D      E5139_04530 chemotaxis response regulator protein-glutamate methylesterase	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      E5139_04465 chemotaxis protein CheD	K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D      E5139_04540 protein-glutamate O-methyltransferase CheR	K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
C    02040 Flagellar assembly
C    04814 Motor proteins
C    04820 Cytoskeleton in muscle cells
D      E5139_00275 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C    04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B  09151 Immune system
C    04640 Hematopoietic cell lineage
C    04610 Complement and coagulation cascades
C    04611 Platelet activation
C    04613 Neutrophil extracellular trap formation
C    04620 Toll-like receptor signaling pathway
C    04624 Toll and Imd signaling pathway
C    04621 NOD-like receptor signaling pathway
C    04622 RIG-I-like receptor signaling pathway
C    04623 Cytosolic DNA-sensing pathway
C    04625 C-type lectin receptor signaling pathway
C    04650 Natural killer cell mediated cytotoxicity
C    04612 Antigen processing and presentation
C    04660 T cell receptor signaling pathway
C    04658 Th1 and Th2 cell differentiation
C    04659 Th17 cell differentiation
C    04657 IL-17 signaling pathway
C    04662 B cell receptor signaling pathway
C    04664 Fc epsilon RI signaling pathway
C    04666 Fc gamma R-mediated phagocytosis
C    04670 Leukocyte transendothelial migration
C    04672 Intestinal immune network for IgA production
C    04062 Chemokine signaling pathway
B
B  09152 Endocrine system
C    04911 Insulin secretion
C    04910 Insulin signaling pathway
C    04922 Glucagon signaling pathway
C    04923 Regulation of lipolysis in adipocytes
C    04920 Adipocytokine signaling pathway
C    03320 PPAR signaling pathway
C    04929 GnRH secretion
C    04912 GnRH signaling pathway
C    04913 Ovarian steroidogenesis
C    04915 Estrogen signaling pathway
C    04914 Progesterone-mediated oocyte maturation
C    04917 Prolactin signaling pathway
C    04921 Oxytocin signaling pathway
C    04926 Relaxin signaling pathway
C    04935 Growth hormone synthesis, secretion and action
C    04918 Thyroid hormone synthesis
C    04919 Thyroid hormone signaling pathway
C    04928 Parathyroid hormone synthesis, secretion and action
C    04916 Melanogenesis
C    04924 Renin secretion
C    04614 Renin-angiotensin system
C    04925 Aldosterone synthesis and secretion
C    04927 Cortisol synthesis and secretion
B
B  09153 Circulatory system
C    04260 Cardiac muscle contraction
C    04261 Adrenergic signaling in cardiomyocytes
C    04270 Vascular smooth muscle contraction
B
B  09154 Digestive system
C    04970 Salivary secretion
C    04971 Gastric acid secretion
C    04972 Pancreatic secretion
C    04976 Bile secretion
C    04973 Carbohydrate digestion and absorption
C    04974 Protein digestion and absorption
C    04975 Fat digestion and absorption
C    04979 Cholesterol metabolism
C    04977 Vitamin digestion and absorption
C    04980 Cobalamin transport and metabolism [PATH:halz04980]
D      E5139_12635 cob(I)yrinic acid a,c-diamide adenosyltransferase	K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D      E5139_01320 meaB; methylmalonyl Co-A mutase-associated GTPase MeaB	K07588 MMAA; GTPase [EC:3.6.5.-]
C    04978 Mineral absorption
B
B  09155 Excretory system
C    04962 Vasopressin-regulated water reabsorption
C    04960 Aldosterone-regulated sodium reabsorption
C    04961 Endocrine and other factor-regulated calcium reabsorption
C    04964 Proximal tubule bicarbonate reclamation
C    04966 Collecting duct acid secretion
B
B  09156 Nervous system
C    04724 Glutamatergic synapse
C    04727 GABAergic synapse
C    04725 Cholinergic synapse
C    04728 Dopaminergic synapse
C    04726 Serotonergic synapse
C    04720 Long-term potentiation
C    04730 Long-term depression
C    04723 Retrograde endocannabinoid signaling
C    04721 Synaptic vesicle cycle
C    04722 Neurotrophin signaling pathway
B
B  09157 Sensory system
C    04744 Phototransduction
C    04745 Phototransduction - fly
C    04740 Olfactory transduction
C    04742 Taste transduction
C    04750 Inflammatory mediator regulation of TRP channels
B
B  09158 Development and regeneration
C    04320 Dorso-ventral axis formation
C    04360 Axon guidance
C    04361 Axon regeneration
C    04380 Osteoclast differentiation
B
B  09149 Aging
C    04211 Longevity regulating pathway
C    04212 Longevity regulating pathway - worm
C    04213 Longevity regulating pathway - multiple species
B
B  09159 Environmental adaptation
C    04710 Circadian rhythm
C    04713 Circadian entrainment
C    04711 Circadian rhythm - fly
C    04712 Circadian rhythm - plant
C    04714 Thermogenesis
C    04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B  09161 Cancer: overview
C    05200 Pathways in cancer
C    05202 Transcriptional misregulation in cancer
C    05206 MicroRNAs in cancer
C    05205 Proteoglycans in cancer
C    05204 Chemical carcinogenesis - DNA adducts
C    05207 Chemical carcinogenesis - receptor activation
C    05208 Chemical carcinogenesis - reactive oxygen species
C    05203 Viral carcinogenesis
C    05230 Central carbon metabolism in cancer
C    05231 Choline metabolism in cancer
C    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B  09162 Cancer: specific types
C    05210 Colorectal cancer
C    05212 Pancreatic cancer
C    05225 Hepatocellular carcinoma
C    05226 Gastric cancer
C    05214 Glioma
C    05216 Thyroid cancer
C    05221 Acute myeloid leukemia
C    05220 Chronic myeloid leukemia
C    05217 Basal cell carcinoma
C    05218 Melanoma
C    05211 Renal cell carcinoma
C    05219 Bladder cancer
C    05215 Prostate cancer
C    05213 Endometrial cancer
C    05224 Breast cancer
C    05222 Small cell lung cancer
C    05223 Non-small cell lung cancer
B
B  09172 Infectious disease: viral
C    05166 Human T-cell leukemia virus 1 infection
C    05170 Human immunodeficiency virus 1 infection
C    05161 Hepatitis B
C    05160 Hepatitis C
C    05171 Coronavirus disease - COVID-19
C    05164 Influenza A
C    05162 Measles
C    05168 Herpes simplex virus 1 infection
C    05163 Human cytomegalovirus infection
C    05167 Kaposi sarcoma-associated herpesvirus infection
C    05169 Epstein-Barr virus infection
C    05165 Human papillomavirus infection
B
B  09171 Infectious disease: bacterial
C    05110 Vibrio cholerae infection
C    05120 Epithelial cell signaling in Helicobacter pylori infection
C    05130 Pathogenic Escherichia coli infection
C    05132 Salmonella infection
C    05131 Shigellosis
C    05135 Yersinia infection
C    05133 Pertussis
C    05134 Legionellosis
C    05150 Staphylococcus aureus infection
C    05152 Tuberculosis
C    05100 Bacterial invasion of epithelial cells
B
B  09174 Infectious disease: parasitic
C    05146 Amoebiasis
C    05144 Malaria
C    05145 Toxoplasmosis
C    05140 Leishmaniasis
C    05142 Chagas disease
C    05143 African trypanosomiasis
B
B  09163 Immune disease
C    05310 Asthma
C    05322 Systemic lupus erythematosus
C    05323 Rheumatoid arthritis
C    05320 Autoimmune thyroid disease
C    05321 Inflammatory bowel disease
C    05330 Allograft rejection
C    05332 Graft-versus-host disease
C    05340 Primary immunodeficiency
B
B  09164 Neurodegenerative disease
C    05010 Alzheimer disease
C    05012 Parkinson disease
C    05014 Amyotrophic lateral sclerosis
C    05016 Huntington disease
C    05017 Spinocerebellar ataxia
C    05020 Prion disease
C    05022 Pathways of neurodegeneration - multiple diseases
B
B  09165 Substance dependence
C    05030 Cocaine addiction
C    05031 Amphetamine addiction
C    05032 Morphine addiction
C    05033 Nicotine addiction
C    05034 Alcoholism
B
B  09166 Cardiovascular disease
C    05417 Lipid and atherosclerosis
C    05418 Fluid shear stress and atherosclerosis
C    05410 Hypertrophic cardiomyopathy
C    05412 Arrhythmogenic right ventricular cardiomyopathy
C    05414 Dilated cardiomyopathy
C    05415 Diabetic cardiomyopathy
C    05416 Viral myocarditis
B
B  09167 Endocrine and metabolic disease
C    04930 Type II diabetes mellitus
C    04940 Type I diabetes mellitus
C    04950 Maturity onset diabetes of the young
C    04936 Alcoholic liver disease
C    04932 Non-alcoholic fatty liver disease
C    04931 Insulin resistance
C    04933 AGE-RAGE signaling pathway in diabetic complications
C    04934 Cushing syndrome
B
B  09175 Drug resistance: antimicrobial
C    01501 beta-Lactam resistance [PATH:halz01501]
D      E5139_03100 nagZ; beta-N-acetylhexosaminidase	K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
C    01502 Vancomycin resistance
C    01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:halz01503]
D      E5139_15555 PDZ domain-containing protein	K04771 degP; serine protease Do [EC:3.4.21.107]
D      E5139_11080 peptidylprolyl isomerase	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
B
B  09176 Drug resistance: antineoplastic
C    01521 EGFR tyrosine kinase inhibitor resistance
C    01524 Platinum drug resistance
C    01523 Antifolate resistance
C    01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B  09181 Protein families: metabolism
C    01000 Enzymes [BR:halz01000]
C    01001 Protein kinases [BR:halz01001]
D      E5139_09040 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase	K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D      E5139_06685 serine protein kinase RIO	K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D      E5139_04275 serine/threonine protein phosphatase	K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D      E5139_02835 FHA domain-containing protein	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16135 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16140 serine/threonine-protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16310 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16315 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16320 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16330 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16335 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16375 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16380 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_16405 serine/threonine protein kinase	K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D      E5139_06285 histidine kinase	K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
D      E5139_08155 HAMP domain-containing histidine kinase	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_04215 histidine kinase	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_13470 PAS domain S-box protein	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_14285 two-component sensor histidine kinase	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_04535 chemotaxis protein CheA	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C    01009 Protein phosphatases and associated proteins [BR:halz01009]
D      E5139_15180 translation initiation factor IF-2 subunit beta	K03238 EIF2S2; translation initiation factor 2 subunit 2
D      E5139_09780 translation initiation factor IF-2 subunit beta	K03238 EIF2S2; translation initiation factor 2 subunit 2
D      E5139_06960 adenosylhomocysteinase	K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D      E5139_16285 serine/threonine-protein phosphatase	K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
D      E5139_02830 serine/threonine-protein phosphatase	K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
D      E5139_07270 serB; phosphoserine phosphatase SerB	K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C    01002 Peptidases and inhibitors [BR:halz01002]
D      E5139_07455 prepilin peptidase	K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D      E5139_08780 hypothetical protein	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      E5139_10130 guaA; glutamine-hydrolyzing GMP synthase subunit GuaA	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      E5139_03470 GMP synthase subunit A	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D      E5139_13620 purF; amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D      E5139_02915 gltB; glutamate synthase large subunit	K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D      E5139_13335 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      E5139_11275 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D      E5139_13050 asparagine synthetase B	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D      E5139_00785 DJ-1/PfpI family protein	K05520 yhbO; deglycase [EC:3.5.1.124]
D      E5139_12870 artA; archaeosortase A	K24447 artA; archaeosortase A [EC:3.4.22.-]
D      E5139_10650 CPBP family intramembrane metalloprotease	K07052 K07052; CAAX protease family protein
D      E5139_08505 CPBP family intramembrane metalloprotease	K07052 K07052; CAAX protease family protein
D      E5139_03155 CPBP family intramembrane metalloprotease	K07052 K07052; CAAX protease family protein
D      E5139_03220 CPBP family intramembrane metalloprotease	K07052 K07052; CAAX protease family protein
D      E5139_09745 CPBP family intramembrane metalloprotease	K07052 K07052; CAAX protease family protein
D      E5139_09690 pepF; oligoendopeptidase F	K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D      E5139_03480 oligoendopeptidase F family protein	K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D      E5139_03055 M20 family metallopeptidase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D      E5139_02880 amidohydrolase	K12940 abgA; aminobenzoyl-glutamate utilization protein A
D      E5139_10680 type II methionyl aminopeptidase	K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D      E5139_00495 aminopeptidase P family protein	K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D      E5139_04575 aminopeptidase	K19689 ampS; aminopeptidase [EC:3.4.11.-]
D      E5139_07305 aminopeptidase	K19689 ampS; aminopeptidase [EC:3.4.11.-]
D      E5139_04700 carboxypeptidase M32	K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D      E5139_03290 hypothetical protein	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      E5139_09155 htpX; zinc metalloprotease HtpX	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      E5139_05150 protease	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      E5139_13090 peptidase M48 Ste24p	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D      E5139_04820 archaemetzincin family Zn-dependent metalloprotease	K06974 amzA; archaemetzincin [EC:3.4.-.-]
D      E5139_03015 PrsW family intramembrane metalloprotease	K24131 prsW; protease PrsW [EC:3.4.-.-]
D      E5139_05895 PrsW family intramembrane metalloprotease	K24131 prsW; protease PrsW [EC:3.4.-.-]
D      E5139_15555 PDZ domain-containing protein	K04771 degP; serine protease Do [EC:3.4.21.107]
D      E5139_01495 PKD domain-containing protein	K14645 K14645; serine protease [EC:3.4.21.-]
D      E5139_00980 peptidase S8/S53 subtilisin kexin sedolisin	K14645 K14645; serine protease [EC:3.4.21.-]
D      E5139_03225 lonB; ATP-dependent protease LonB	K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D      E5139_10070 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      E5139_08060 signal peptidase I	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      E5139_07245 S26 family signal peptidase	K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D      E5139_11060 alpha/beta fold hydrolase	K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
D      E5139_01415 sppA; signal peptide peptidase SppA	K04773 sppA; protease IV [EC:3.4.21.-]
D      E5139_04285 S49 family peptidase	K04773 sppA; protease IV [EC:3.4.21.-]
D      E5139_02105 rhomboid family intramembrane serine protease	K07059 K07059; rhomboid family protein
D      E5139_15135 psmA; archaeal proteasome endopeptidase complex subunit alpha	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      E5139_03420 psmA; archaeal proteasome endopeptidase complex subunit alpha	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      E5139_03415 psmB; archaeal proteasome endopeptidase complex subunit beta	K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D      E5139_10670 asparaginase	K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D      E5139_04745 ggt; gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C    01003 Glycosyltransferases [BR:halz01003]
D      E5139_15590 aglJ; S-layer glycoprotein N-glycosyltransferase AglJ	K23684 aglJ; dolichol-phosphate hexosyltransferase [EC:2.4.1.-]
D      E5139_01060 glycosyltransferase family 2 protein	K22844 aglG; glucosyl-dolichyl phosphate glucuronosyltransferase [EC:2.4.1.356]
D      E5139_02410 glycosyltransferase	K23683 aglD; glycosyltransferase AglD [EC:2.4.1.-]
D      E5139_10540 hypothetical protein	K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
D      E5139_01055 oligosaccharyl transferase, archaeosortase A system-associated	K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D      E5139_06400 DUF2029 domain-containing protein	K13669 pimE; alpha-1,2-mannosyltransferase [EC:2.4.1.-]
D      E5139_11410 glycosyltransferase family 2 protein	K19003 mgdA; 1,2-diacylglycerol 3-beta-glucosyltransferase [EC:2.4.1.336]
D      E5139_13105 glycosyltransferase	K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D      E5139_12805 glycoside hydrolase family 68 protein	K00692 sacB; levansucrase [EC:2.4.1.10]
D      E5139_10415 sugar transferase	K13656 gumD; undecaprenyl-phosphate glucose phosphotransferase [EC:2.7.8.31]
D      E5139_02490 glycosyl transferase family 2	K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]
C    01005 Lipopolysaccharide biosynthesis proteins [BR:halz01005]
C    01011 Peptidoglycan biosynthesis and degradation proteins [BR:halz01011]
D      E5139_11255 undecaprenyl-diphosphate phosphatase	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D      E5139_12870 artA; archaeosortase A	K24447 artA; archaeosortase A [EC:3.4.22.-]
C    01004 Lipid biosynthesis proteins [BR:halz01004]
D      E5139_15800 3-oxoacyl-ACP synthase	K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D      E5139_08120 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_14540 beta-ketoacyl-ACP reductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_08275 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_07860 SDR family oxidoreductase	K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D      E5139_13415 acetyl-CoA synthetase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_13980 acs; acetate--CoA ligase	K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D      E5139_14590 CoA-binding protein	K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D      E5139_15760 long-chain fatty acid--CoA ligase	K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C    01008 Polyketide biosynthesis proteins [BR:halz01008]
D      E5139_11860 CRTAC1 family protein	K21162 sgcE4; enediyne biosynthesis protein E4
C    01006 Prenyltransferases [BR:halz01006]
D      E5139_00325 polyprenyl synthetase family protein	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      E5139_09505 polyprenyl synthetase family protein	K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D      E5139_10860 undecaprenyl diphosphate synthase family protein	K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D      E5139_07670 squalene/phytoene synthase	K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
D      E5139_04670 phytoene/squalene synthase family protein	K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D      E5139_14395 1,4-dihydroxy-2-naphthoate polyprenyltransferase	K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D      E5139_01280 cyoE; protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
C    01007 Amino acid related enzymes [BR:halz01007]
D      E5139_09625 lysine--tRNA ligase	K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D      E5139_00330 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      E5139_00090 tyrosine--tRNA ligase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      E5139_06500 tryptophan--tRNA ligase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      E5139_14045 cysteine--tRNA ligase	K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D      E5139_09615 arginine--tRNA ligase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      E5139_02240 metG; methionine--tRNA ligase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D      E5139_08460 isoleucine--tRNA ligase	K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D      E5139_10805 valine--tRNA ligase	K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D      E5139_07665 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_06585 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_02485 aspS; aspartate--tRNA(Asn) ligase	K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D      E5139_09670 histidine--tRNA ligase	K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D      E5139_07150 glyS; glycine--tRNA ligase	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      E5139_06900 serS; serine--tRNA ligase	K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D      E5139_02900 proline--tRNA ligase	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      E5139_10105 thrS; threonine--tRNA ligase	K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D      E5139_08795 alanine--tRNA ligase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      E5139_06495 phenylalanine--tRNA ligase subunit alpha	K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D      E5139_06490 phenylalanine--tRNA ligase subunit beta	K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D      E5139_01390 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_12670 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_02090 pyridoxal phosphate-dependent aminotransferase	K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D      E5139_13890 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	K10907 K10907; aminotransferase [EC:2.6.1.-]
D      E5139_15005 histidinol-phosphate transaminase	K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D      E5139_14605 8-amino-7-oxononanoate synthase	K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D      E5139_07060 aspartate aminotransferase family protein	K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D      E5139_14175 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D      E5139_16515 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D      E5139_07735 glutamate-1-semialdehyde 2,1-aminomutase	K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D      E5139_01920 aminodeoxychorismate lyase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_08720 branched-chain amino acid transaminase	K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D      E5139_13305 DegT/DnrJ/EryC1/StrS aminotransferase family protein	K13010 per; perosamine synthetase [EC:2.6.1.102]
C    00199 Cytochrome P450
C    00194 Photosynthesis proteins
B
B  09182 Protein families: genetic information processing
C    03000 Transcription factors [BR:halz03000]
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
D      E5139_05510 DNA cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      E5139_06785 TATA-box-binding protein	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      E5139_00590 DeoR/GlpR transcriptional regulator	K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
D      E5139_13955 Lrp/AsnC family transcriptional regulator	K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D      E5139_12860 MarR family transcriptional regulator	K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D      E5139_07895 IclR family transcriptional regulator	K21827 arcR; IclR family transcriptional regulator, arginine deiminase pathway regulator
D      E5139_15030 helix-turn-helix transcriptional regulator	K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D      E5139_12175 winged helix-turn-helix transcriptional regulator	K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D      E5139_16585 winged helix-turn-helix transcriptional regulator	K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D      E5139_10030 metalloregulator ArsR/SmtB family transcription factor	K07721 K07721; ArsR family transcriptional regulator
D      E5139_09920 transcriptional regulator	K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D      E5139_03435 helix-turn-helix domain-containing protein	K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D      E5139_05935 PadR family transcriptional regulator	K23305 gvpE; PadR family transcriptional regulator, activator of gas vesicle formation
D      E5139_00770 metal-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      E5139_01905 metal-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      E5139_16245 metal-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      E5139_05220 metal-dependent transcriptional regulator	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D      E5139_00150 biotin--[acetyl-CoA-carboxylase] ligase	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D      E5139_07480 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_13260 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_14460 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_14500 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_11035 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_03535 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_04335 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_14150 TrmB family transcriptional regulator	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_04210 hypothetical protein	K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D      E5139_03380 PAS domain S-box protein	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      E5139_06590 PAS domain S-box protein	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      E5139_16765 PAS domain S-box protein	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      E5139_02990 PAS domain S-box protein	K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D      E5139_10905 bacterio-opsin activator	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      E5139_16220 bacterio-opsin activator	K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D      E5139_14450 orotate phosphoribosyltransferase-like protein	K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D      E5139_10190 LysR family transcriptional regulator	K02019 modE; molybdate transport system regulatory protein
D      E5139_07410 transcriptional regulator	K07728 K07728; putative transcriptional regulator
D      E5139_05415 transcriptional regulator	K07729 K07729; putative transcriptional regulator
D      E5139_13435 winged helix-turn-helix transcriptional regulator	K07730 K07730; putative transcriptional regulator
D      E5139_11845 helix-turn-helix domain-containing protein	K07731 K07731; putative transcriptional regulator
D      E5139_04780 nikR; nickel-responsive transcriptional regulator NikR	K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D      E5139_12610 CopG family ribbon-helix-helix protein	K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D      E5139_16620 nrdR; transcriptional repressor NrdR	K07738 nrdR; transcriptional repressor NrdR
C    03021 Transcription machinery [BR:halz03021]
D      E5139_15190 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_02415 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_00685 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_08415 transcription initiation factor IIB family protein	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_13075 transcription initiation factor IIB	K03124 TFIIB; transcription initiation factor TFIIB
D      E5139_06785 TATA-box-binding protein	K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D      E5139_14785 transcription factor	K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D      E5139_02965 helicase	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      E5139_02150 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_07280 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_06815 DNA-directed RNA polymerase, subunit E''	K15171 SUPT4H1; transcription elongation factor SPT4
D      E5139_01970 transcription elongation factor Spt5	K15172 SUPT5H; transcription elongation factor SPT5
D      E5139_05675 NusA-like transcription termination signal-binding factor	K02600 nusA; transcription termination/antitermination protein NusA
D      E5139_05685 DNA-directed RNA polymerase subunit A'	K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D      E5139_05680 rpoA2; DNA-directed RNA polymerase subunit A''	K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D      E5139_05690 rpoB; DNA-directed RNA polymerase subunit B	K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D      E5139_05695 DNA-directed RNA polymerase subunit B''	K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D      E5139_00240 DNA-directed RNA polymerase subunit D	K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D      E5139_06820 DNA-directed RNA polymerase	K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D      E5139_00655 RNA polymerase Rpb4 family protein	K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D      E5139_05700 DNA-directed RNA polymerase subunit H	K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D      E5139_00270 DNA-directed RNA polymerase subunit K	K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D      E5139_12920 DNA-directed RNA polymerase subunit L	K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D      E5139_00265 DNA-directed RNA polymerase subunit N	K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D      E5139_03390 DNA-directed RNA polymerase subunit P	K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D      E5139_03165 transcription factor S	K03057 tfs; transcription factor S
D      E5139_09940 transcription factor S	K03057 tfs; transcription factor S
D      E5139_02690 DNA-directed RNA polymerase subunit M	K03057 tfs; transcription factor S
C    03019 Messenger RNA biogenesis [BR:halz03019]
D      E5139_06815 DNA-directed RNA polymerase, subunit E''	K15171 SUPT4H1; transcription elongation factor SPT4
D      E5139_01970 transcription elongation factor Spt5	K15172 SUPT5H; transcription elongation factor SPT5
D      E5139_12020 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_13590 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_13745 mRNA surveillance protein pelota	K06965 PELO; protein pelota
D      E5139_09605 prf1; peptide chain release factor 1	K03265 ETF1; peptide chain release factor subunit 1
D      E5139_05605 tuf; translation elongation factor EF-1 subunit alpha	K03231 EEF1A; elongation factor 1-alpha
D      E5139_12180 GTP-binding protein	K03231 EEF1A; elongation factor 1-alpha
D      E5139_00320 ribonuclease J	K12574 rnj; ribonuclease J [EC:3.1.-.-]
D      E5139_04655 RNB domain-containing ribonuclease	K12573 rnr; ribonuclease R [EC:3.1.13.1]
D      E5139_00275 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      E5139_01505 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK
D      E5139_16085 grpE; nucleotide exchange factor GrpE	K04043 dnaK; molecular chaperone DnaK
D      E5139_12095 ppk1; polyphosphate kinase 1	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D      E5139_08340 DEAD/DEAH box helicase	K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C    03041 Spliceosome
C    03011 Ribosome [BR:halz03011]
D      E5139_13795 30S ribosomal protein S3ae	K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D      E5139_12320 30S ribosomal protein S4e	K02987 RP-S4e; small subunit ribosomal protein S4e
D      E5139_04565 30S ribosomal protein S6e	K02991 RP-S6e; small subunit ribosomal protein S6e
D      E5139_12105 30S ribosomal protein S8e	K02995 RP-S8e; small subunit ribosomal protein S8e
D      E5139_00195 30S ribosomal protein S17e	K02962 RP-S17e; small subunit ribosomal protein S17e
D      E5139_09655 30S ribosomal protein S19e	K02966 RP-S19e; small subunit ribosomal protein S19e
D      E5139_09030 rps24e; 30S ribosomal protein S24e	K02974 RP-S24e; small subunit ribosomal protein S24e
D      E5139_01675 30S ribosomal protein S27e	K02978 RP-S27e; small subunit ribosomal protein S27e
D      E5139_09035 30S ribosomal protein S27ae	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D      E5139_00385 30S ribosomal protein S28e	K02979 RP-S28e; small subunit ribosomal protein S28e
D      E5139_12265 50S ribosomal protein L4	K02930 RP-L4e; large subunit ribosomal protein L4e
D      E5139_00380 50S ribosomal protein L7ae	K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D      E5139_06420 50S ribosomal protein L16	K02866 RP-L10e; large subunit ribosomal protein L10e
D      E5139_04675 50S ribosomal protein L15e	K02877 RP-L15e; large subunit ribosomal protein L15e
D      E5139_00250 50S ribosomal protein L18e	K02883 RP-L18e; large subunit ribosomal protein L18e
D      E5139_12350 50S ribosomal protein L19e	K02885 RP-L19e; large subunit ribosomal protein L19e
D      E5139_00660 50S ribosomal protein L21e	K02889 RP-L21e; large subunit ribosomal protein L21e
D      E5139_09340 50S ribosomal protein L31e	K02910 RP-L31e; large subunit ribosomal protein L31e
D      E5139_12345 50S ribosomal protein L32e	K02912 RP-L32e; large subunit ribosomal protein L32e
D      E5139_13625 50S ribosomal protein L37e	K02922 RP-L37e; large subunit ribosomal protein L37e
D      E5139_03395 50S ribosomal protein L37ae	K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D      E5139_09345 50S ribosomal protein L39e	K02924 RP-L39e; large subunit ribosomal protein L39e
D      E5139_06775 50S ribosomal protein L40e	K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D      E5139_01670 50S ribosomal protein L44e	K02929 RP-L44e; large subunit ribosomal protein L44e
D      E5139_00280 30S ribosomal protein S2	K02967 RP-S2; small subunit ribosomal protein S2
D      E5139_12290 30S ribosomal protein S3	K02982 RP-S3; small subunit ribosomal protein S3
D      E5139_00230 30S ribosomal protein S4	K02986 RP-S4; small subunit ribosomal protein S4
D      E5139_12360 30S ribosomal protein S5	K02988 RP-S5; small subunit ribosomal protein S5
D      E5139_05665 30S ribosomal protein S7	K02992 RP-S7; small subunit ribosomal protein S7
D      E5139_12335 30S ribosomal protein S8	K02994 RP-S8; small subunit ribosomal protein S8
D      E5139_00260 30S ribosomal protein S9	K02996 RP-S9; small subunit ribosomal protein S9
D      E5139_05600 30S ribosomal protein S10	K02946 RP-S10; small subunit ribosomal protein S10
D      E5139_02610 30S ribosomal protein S10	K02946 RP-S10; small subunit ribosomal protein S10
D      E5139_00235 30S ribosomal protein S11	K02948 RP-S11; small subunit ribosomal protein S11
D      E5139_05670 30S ribosomal protein S12	K02950 RP-S12; small subunit ribosomal protein S12
D      E5139_00225 30S ribosomal protein S13	K02952 RP-S13; small subunit ribosomal protein S13
D      E5139_12330 30S ribosomal protein S14	K02954 RP-S14; small subunit ribosomal protein S14
D      E5139_13810 30S ribosomal protein S15	K02956 RP-S15; small subunit ribosomal protein S15
D      E5139_12305 30S ribosomal protein S17	K02961 RP-S17; small subunit ribosomal protein S17
D      E5139_12280 30S ribosomal protein S19	K02965 RP-S19; small subunit ribosomal protein S19
D      E5139_14070 50S ribosomal protein L1	K02863 RP-L1; large subunit ribosomal protein L1
D      E5139_12275 50S ribosomal protein L2	K02886 RP-L2; large subunit ribosomal protein L2
D      E5139_12260 50S ribosomal protein L3	K02906 RP-L3; large subunit ribosomal protein L3
D      E5139_12325 50S ribosomal protein L5	K02931 RP-L5; large subunit ribosomal protein L5
D      E5139_12340 50S ribosomal protein L6	K02933 RP-L6; large subunit ribosomal protein L6
D      E5139_14065 50S ribosomal protein L10	K02864 RP-L10; large subunit ribosomal protein L10
D      E5139_14075 50S ribosomal protein L11	K02867 RP-L11; large subunit ribosomal protein L11
D      E5139_00255 50S ribosomal protein L13	K02871 RP-L13; large subunit ribosomal protein L13
D      E5139_12310 50S ribosomal protein L14	K02874 RP-L14; large subunit ribosomal protein L14
D      E5139_12370 50S ribosomal protein L15	K02876 RP-L15; large subunit ribosomal protein L15
D      E5139_12355 50S ribosomal protein L18	K02881 RP-L18; large subunit ribosomal protein L18
D      E5139_12285 50S ribosomal protein L22	K02890 RP-L22; large subunit ribosomal protein L22
D      E5139_12270 50S ribosomal protein L23	K02892 RP-L23; large subunit ribosomal protein L23
D      E5139_12315 50S ribosomal protein L24	K02895 RP-L24; large subunit ribosomal protein L24
D      E5139_12295 rpmC; 50S ribosomal protein L29	K02904 RP-L29; large subunit ribosomal protein L29
D      E5139_12365 rpmD; 50S ribosomal protein L30	K02907 RP-L30; large subunit ribosomal protein L30
D      E5139_14060 50S ribosomal protein P1	K02869 RP-L12; large subunit ribosomal protein L12
D      E5139_09330 50S ribosomal protein L18a	K02944 RP-LX; large subunit ribosomal protein LX
D      E5139_13380 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_06455 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_16025 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_16035 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_06470 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_13370 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_13375 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_06460 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_16030 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
C    03009 Ribosome biogenesis [BR:halz03009]
D      E5139_01685 RNA-protein complex protein Nop10	K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D      E5139_06680 RNA-processing protein	K06961 KRR1; ribosomal RNA assembly protein
D      E5139_06685 serine protein kinase RIO	K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D      E5139_04275 serine/threonine protein phosphatase	K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D      E5139_15000 adenylate kinase	K18532 AK6; adenylate kinase [EC:2.7.4.3]
D      E5139_06925 DUF367 family protein	K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D      E5139_04830 ribosome biogenesis/translation initiation ATPase RLI	K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D      E5139_05865 GTP-binding protein	K06943 NOG1; nucleolar GTP-binding protein
D      E5139_12300 ribonuclease P protein component 1	K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D      E5139_15130 ribonuclease P	K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D      E5139_15115 ribonuclease P	K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D      E5139_09335 translation initiation factor IF-6	K03264 EIF6; translation initiation factor 6
D      E5139_09165 hypothetical protein	K07562 NMD3; 60S ribosomal export protein NMD3
D      E5139_15140 ribosome assembly factor SBDS	K14574 SDO1; ribosome maturation protein SDO1
D      E5139_12020 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_13590 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_07235 GTP-binding protein	K03595 era; GTPase
D      E5139_00380 50S ribosomal protein L7ae	K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D      E5139_01235 H/ACA RNA-protein complex protein Gar1	K07569 gar1; RNA-binding protein
D      E5139_05675 NusA-like transcription termination signal-binding factor	K02600 nusA; transcription termination/antitermination protein NusA
D      E5139_00645 16S ribosomal RNA methyltransferase A	K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D      E5139_08255 TRAM domain-containing protein	K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D      E5139_10850 GNAT family N-acetyltransferase	K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D      E5139_06150 rimI; ribosomal-protein-alanine N-acetyltransferase	K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D      E5139_06435 RimK family alpha-L-glutamate ligase	K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D      E5139_14230 bacteriocin biosynthesis protein SagD	K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor
D      E5139_15150 hflX; GTPase HflX	K03665 hflX; GTPase
D      E5139_07610 threonylcarbamoyl-AMP synthase	K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D      E5139_13115 YhbY family RNA-binding protein	K07574 yhbY; RNA-binding protein
D      E5139_01355 ychF; redox-regulated ATPase YchF	K06942 ychF; ribosome-binding ATPase
D      E5139_09830 ychF; redox-regulated ATPase YchF	K06942 ychF; ribosome-binding ATPase
D      E5139_04860 DUF402 domain-containing protein	K22469 fau-1; probable ribonuclease FAU-1 [EC:3.1.26.-]
C    03016 Transfer RNA biogenesis [BR:halz03016]
D      E5139_12300 ribonuclease P protein component 1	K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D      E5139_15130 ribonuclease P	K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D      E5139_15115 ribonuclease P	K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D      E5139_13110 ribonuclease P	K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D      E5139_08515 rnz; ribonuclease Z	K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D      E5139_02775 RNA-splicing ligase RtcB	K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D      E5139_05605 tuf; translation elongation factor EF-1 subunit alpha	K03231 EEF1A; elongation factor 1-alpha
D      E5139_12180 GTP-binding protein	K03231 EEF1A; elongation factor 1-alpha
D      E5139_00330 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      E5139_02900 proline--tRNA ligase	K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D      E5139_08460 isoleucine--tRNA ligase	K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D      E5139_07665 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_06585 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_02240 metG; methionine--tRNA ligase	K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D      E5139_09615 arginine--tRNA ligase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      E5139_08795 alanine--tRNA ligase	K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D      E5139_07150 glyS; glycine--tRNA ligase	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      E5139_10105 thrS; threonine--tRNA ligase	K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D      E5139_06900 serS; serine--tRNA ligase	K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D      E5139_14045 cysteine--tRNA ligase	K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D      E5139_10805 valine--tRNA ligase	K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D      E5139_09670 histidine--tRNA ligase	K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D      E5139_06495 phenylalanine--tRNA ligase subunit alpha	K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D      E5139_06490 phenylalanine--tRNA ligase subunit beta	K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D      E5139_00090 tyrosine--tRNA ligase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      E5139_06500 tryptophan--tRNA ligase	K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D      E5139_01950 hypothetical protein	K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D      E5139_08430 HIT family protein	K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D      E5139_10740 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase	K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D      E5139_06745 tRNA (guanine(26)-N(2))-dimethyltransferase	K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D      E5139_12880 class I SAM-dependent methyltransferase family protein	K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D      E5139_03150 tRNA (adenine-N1)-methyltransferase	K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D      E5139_00095 class I SAM-dependent methyltransferase	K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D      E5139_09205 4-demethylwyosine synthase TYW1	K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D      E5139_09175 class I SAM-dependent methyltransferase family protein	K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D      E5139_09685 truA; tRNA pseudouridine(38-40) synthase TruA	K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D      E5139_11790 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5	K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D      E5139_03410 truD; tRNA pseudouridine(13) synthase TruD	K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D      E5139_11240 tRNA pseudouridine(54/55) synthase Pus10	K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D      E5139_14100 tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3	K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D      E5139_07610 threonylcarbamoyl-AMP synthase	K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D      E5139_04595 rnpB; RNase P RNA component	K01978 rnpB; M1 RNA
D      E5139_05955 CCA tRNA nucleotidyltransferase	K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D      E5139_06505 endA; tRNA-intron lyase	K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D      E5139_09365 thpR; RNA 2',3'-cyclic phosphodiesterase	K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D      E5139_09625 lysine--tRNA ligase	K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D      E5139_02485 aspS; aspartate--tRNA(Asn) ligase	K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D      E5139_10395 trmY; tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY	K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D      E5139_06790 methyltransferase domain-containing protein	K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D      E5139_14765 tRNA (cytidine(56)-2'-O)-methyltransferase	K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D      E5139_01425 RsmB/NOP family class I SAM-dependent RNA methyltransferase	K22446 K22446; tRNA (cytosine49-C5)-methyltransferase [EC:2.1.1.-]
D      E5139_16270 sulfurtransferase TusA family protein	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      E5139_16780 hypothetical protein	K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D      E5139_15390 iron-sulfur cluster assembly accessory protein	K13628 iscA; iron-sulfur cluster assembly protein
D      E5139_09040 bifunctional N(6)-L-threonylcarbamoyladenine synthase/serine/threonine protein kinase	K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D      E5139_06625 KEOPS complex component	K09119 cgi121; KEOPS complex subunit Cgi121
D      E5139_03385 rpo operon protein	K09741 pcc1; KEOPS complex subunit Pcc1
D      E5139_06120 queC; 7-cyano-7-deazaguanine synthase QueC	K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D      E5139_06105 6-pyruvoyl tetrahydropterin synthase family protein	K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D      E5139_06110 7-carboxy-7-deazaguanine synthase QueE	K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D      E5139_10325 tgtA; tRNA guanosine(15) transglycosylase TgtA	K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D      E5139_14670 tRNA sulfurtransferase	K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D      E5139_07405 DUF1743 domain-containing protein	K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D      E5139_00375 tRNA(Met) cytidine acetyltransferase	K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D      E5139_04655 RNB domain-containing ribonuclease	K12573 rnr; ribonuclease R [EC:3.1.13.1]
D      E5139_03610 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D      E5139_00050 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D      E5139_04630 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
C    03012 Translation factors [BR:halz03012]
D      E5139_06690 eif1A; translation initiation factor eIF-1A	K03236 EIF1A; translation initiation factor 1A
D      E5139_05270 translation initiation factor IF-1A	K03236 EIF1A; translation initiation factor 1A
D      E5139_06290 yciH; stress response translation initiation inhibitor YciH	K03113 EIF1; translation initiation factor 1
D      E5139_01680 translation initiation factor IF-2 subunit alpha	K03237 EIF2S1; translation initiation factor 2 subunit 1
D      E5139_15180 translation initiation factor IF-2 subunit beta	K03238 EIF2S2; translation initiation factor 2 subunit 2
D      E5139_09780 translation initiation factor IF-2 subunit beta	K03238 EIF2S2; translation initiation factor 2 subunit 2
D      E5139_06830 translation initiation factor IF-2 subunit gamma	K03242 EIF2S3; translation initiation factor 2 subunit 3
D      E5139_15520 translation initiation factor eIF-2B	K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
D      E5139_11150 translation initiation factor IF-5A	K03263 EIF5A; translation initiation factor 5A
D      E5139_09720 infB; translation initiation factor IF-2	K03243 EIF5B; translation initiation factor 5B
D      E5139_09335 translation initiation factor IF-6	K03264 EIF6; translation initiation factor 6
D      E5139_05605 tuf; translation elongation factor EF-1 subunit alpha	K03231 EEF1A; elongation factor 1-alpha
D      E5139_12180 GTP-binding protein	K03231 EEF1A; elongation factor 1-alpha
D      E5139_00665 elongation factor 1-beta	K03232 EEF1B; elongation factor 1-beta
D      E5139_05640 elongation factor EF-2	K03234 EEF2; elongation factor 2
D      E5139_15600 dph2; diphthamide biosynthesis enzyme Dph2	K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D      E5139_01400 diphthine--ammonia ligase	K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D      E5139_09605 prf1; peptide chain release factor 1	K03265 ETF1; peptide chain release factor subunit 1
D      E5139_00640 methyltransferase domain-containing protein	K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D      E5139_03425 peptidyl-tRNA hydrolase	K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C    03110 Chaperones and folding catalysts [BR:halz03110]
D      E5139_01505 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK
D      E5139_16085 grpE; nucleotide exchange factor GrpE	K04043 dnaK; molecular chaperone DnaK
D      E5139_03245 thermosome subunit	K22447 cct; archaeal chaperonin
D      E5139_06675 thermosome subunit	K22447 cct; archaeal chaperonin
D      E5139_08020 thermosome subunit	K22447 cct; archaeal chaperonin
D      E5139_16340 hypothetical protein	K22447 cct; archaeal chaperonin
D      E5139_01525 dnaJ; molecular chaperone DnaJ	K03686 dnaJ; molecular chaperone DnaJ
D      E5139_15815 molecular chaperone DnaJ	K03686 dnaJ; molecular chaperone DnaJ
D      E5139_01500 grpE; nucleotide exchange factor GrpE	K03687 GRPE; molecular chaperone GrpE
D      E5139_06440 Hsp20/alpha crystallin family protein	K13993 HSP20; HSP20 family protein
D      E5139_08070 Hsp20/alpha crystallin family protein	K13993 HSP20; HSP20 family protein
D      E5139_08575 Hsp20 family protein	K13993 HSP20; HSP20 family protein
D      E5139_02375 Hsp20/alpha crystallin family protein	K13993 HSP20; HSP20 family protein
D      E5139_11165 Hsp20/alpha crystallin family protein	K13993 HSP20; HSP20 family protein
D      E5139_09325 pfdA; prefoldin subunit alpha	K04797 pfdA; prefoldin alpha subunit
D      E5139_03365 prefoldin subunit beta	K04798 pfdB; prefoldin beta subunit
D      E5139_15555 PDZ domain-containing protein	K04771 degP; serine protease Do [EC:3.4.21.107]
D      E5139_10940 cytoplasmic chaperone TorD family protein	K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D      E5139_16195 molecular chaperone	K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D      E5139_01495 PKD domain-containing protein	K14645 K14645; serine protease [EC:3.4.21.-]
D      E5139_00980 peptidase S8/S53 subtilisin kexin sedolisin	K14645 K14645; serine protease [EC:3.4.21.-]
D      E5139_10660 PKD domain-containing protein	K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
D      E5139_11080 peptidylprolyl isomerase	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      E5139_14655 peptidylprolyl isomerase	K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D      E5139_04845 thioredoxin	K03671 TXN; thioredoxin
D      E5139_16810 trxA; thioredoxin	K03671 TXN; thioredoxin
D      E5139_05080 thioredoxin family protein	K03671 TXN; thioredoxin
D      E5139_13390 glutaredoxin	K07390 grxD; monothiol glutaredoxin
C    04131 Membrane trafficking [BR:halz04131]
D      E5139_00395 nucleoside-diphosphate kinase	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D      E5139_12020 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_13590 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_03400 TMEM165/GDT1 family protein	K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D      E5139_02130 ArsA family ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      E5139_16575 arsenic-transporting ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      E5139_01965 protein translocase SEC61 complex subunit gamma	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D      E5139_06445 gap; type I glyceraldehyde-3-phosphate dehydrogenase	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      E5139_15690 pyk; pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      E5139_05605 tuf; translation elongation factor EF-1 subunit alpha	K03231 EEF1A; elongation factor 1-alpha
D      E5139_12180 GTP-binding protein	K03231 EEF1A; elongation factor 1-alpha
C    04121 Ubiquitin system [BR:halz04121]
D      E5139_06775 50S ribosomal protein L40e	K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D      E5139_09035 30S ribosomal protein S27ae	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C    03051 Proteasome [BR:halz03051]
D      E5139_15135 psmA; archaeal proteasome endopeptidase complex subunit alpha	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      E5139_03420 psmA; archaeal proteasome endopeptidase complex subunit alpha	K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D      E5139_03415 psmB; archaeal proteasome endopeptidase complex subunit beta	K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D      E5139_01790 AAA family ATPase	K03420 psmR; proteasome regulatory subunit
D      E5139_09695 AAA family ATPase	K03420 psmR; proteasome regulatory subunit
C    03032 DNA replication proteins [BR:halz03032]
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
D      E5139_02585 ribonuclease HI family protein	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      E5139_01655 reverse transcriptase-like protein	K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D      E5139_08235 DNA polymerase sliding clamp	K04802 PCNA; proliferating cell nuclear antigen
D      E5139_13700 DUF2075 domain-containing protein	K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D      E5139_01190 flap endonuclease-1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      E5139_00920 ATP-dependent DNA ligase	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D      E5139_05510 DNA cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      E5139_01685 RNA-protein complex protein Nop10	K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D      E5139_10845 DNA primase	K02316 dnaG; DNA primase [EC:2.7.7.101]
D      E5139_12190 cell division control protein Cdc6	K10725 cdc6A; archaeal cell division control protein 6
D      E5139_08175 ORC1-type DNA replication protein	K10725 cdc6A; archaeal cell division control protein 6
D      E5139_07240 cell division control protein Cdc6	K10725 cdc6A; archaeal cell division control protein 6
D      E5139_16130 AAA family ATPase	K10725 cdc6A; archaeal cell division control protein 6
D      E5139_08380 AAA family ATPase	K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D      E5139_15545 priS; DNA primase small subunit PriS	K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D      E5139_08125 priL; DNA primase regulatory subunit PriL	K18882 priL; DNA primase large subunit
D      E5139_15550 DNA replication complex GINS family protein	K09723 ginS; DNA replication factor GINS
D      E5139_09775 ribonuclease HII	K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D      E5139_08595 ligA; NAD-dependent DNA ligase LigA	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      E5139_01750 hypothetical protein	K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D      E5139_06995 DNA-directed DNA polymerase II large subunit	K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D      E5139_07250 DNA-directed DNA polymerase II small subunit	K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D      E5139_11910 replication factor C large subunit	K04800 rfcL; replication factor C large subunit
D      E5139_08805 replication factor C small subunit	K04801 rfcS; replication factor C small subunit
D      E5139_09410 AAA family ATPase	K04801 rfcS; replication factor C small subunit
D      E5139_05585 DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      E5139_00955 gyrA; DNA gyrase subunit A	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D      E5139_00950 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D      E5139_00940 DNA topoisomerase IV subunit A	K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D      E5139_00945 DNA topoisomerase VI subunit B	K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D      E5139_06510 DUF91 domain-containing protein	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D      E5139_02320 DNA topoisomerase I	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C    03036 Chromosome and associated proteins [BR:halz03036]
D      E5139_05510 DNA cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      E5139_12255 hypothetical protein	K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D      E5139_05965 aldolase	K24450 hmf; DNA-binding protein
D      E5139_14580 DNA starvation/stationary phase protection protein	K04047 dps; starvation-inducible DNA-binding protein
D      E5139_05225 DNA starvation/stationary phase protection protein	K04047 dps; starvation-inducible DNA-binding protein
D      E5139_02280 smc; chromosome segregation protein SMC	K03529 smc; chromosome segregation protein
D      E5139_02275 segregation/condensation protein A	K05896 scpA; segregation and condensation protein A
D      E5139_01955 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      E5139_04145 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      E5139_14635 cobyrinic acid ac-diamide synthase	K03609 minD; septum site-determining protein MinD
D      E5139_03975 chromosome partitioning protein ParA	K03609 minD; septum site-determining protein MinD
D      E5139_08410 chromosome partitioning protein ParA	K03609 minD; septum site-determining protein MinD
D      E5139_09610 septum site-determining protein MinD	K03609 minD; septum site-determining protein MinD
D      E5139_12825 ParA family protein	K03496 parA; chromosome partitioning protein
D      E5139_10950 Mrp/NBP35 family ATP-binding protein	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      E5139_15455 DUF2249 domain-containing protein	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      E5139_00210 Mrp/NBP35 family ATP-binding protein	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      E5139_13160 Fic family protein	K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
C    03400 DNA repair and recombination proteins [BR:halz03400]
D      E5139_02465 methylated-DNA--[protein]-cysteine S-methyltransferase	K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D      E5139_16705 deoxyribodipyrimidine photo-lyase/cryptochrome family protein	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D      E5139_15850 deoxyribodipyrimidine photo-lyase	K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D      E5139_05500 hypothetical protein	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D      E5139_14140 A/G-specific adenine glycosylase	K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D      E5139_15165 8-oxoguanine DNA glycosylase	K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D      E5139_13195 endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      E5139_02625 endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      E5139_02760 nth; endonuclease III	K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D      E5139_08235 DNA polymerase sliding clamp	K04802 PCNA; proliferating cell nuclear antigen
D      E5139_01190 flap endonuclease-1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      E5139_00920 ATP-dependent DNA ligase	K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D      E5139_02965 helicase	K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D      E5139_02150 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_07280 ATP-dependent DNA helicase	K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D      E5139_05970 single-stranded DNA binding protein	K07466 RFA1; replication factor A1
D      E5139_15100 NUDIX domain-containing protein	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D      E5139_14200 NUDIX hydrolase	K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D      E5139_06135 deoxyuridine 5'-triphosphate nucleotidohydrolase	K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D      E5139_00745 cryptochrome/photolyase family protein	K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D      E5139_06765 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      E5139_00480 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      E5139_00125 uracil-DNA glycosylase	K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D      E5139_13490 DNA-3-methyladenine glycosylase 2 family protein	K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D      E5139_04220 deoxyribonuclease IV	K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D      E5139_02110 endonuclease V	K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D      E5139_08475 DHH family phosphoesterase	K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D      E5139_08595 ligA; NAD-dependent DNA ligase LigA	K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D      E5139_04875 uvrA; excinuclease ABC subunit UvrA	K03701 uvrA; excinuclease ABC subunit A
D      E5139_08930 uvrB; excinuclease ABC subunit UvrB	K03702 uvrB; excinuclease ABC subunit B
D      E5139_08535 excinuclease ABC subunit C	K03703 uvrC; excinuclease ABC subunit C
D      E5139_05920 ATP-dependent helicase	K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D      E5139_05075 mutS; DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      E5139_05115 mutS; DNA mismatch repair protein MutS	K03555 mutS; DNA mismatch repair protein MutS
D      E5139_15285 DNA mismatch repair protein	K07456 mutS2; DNA mismatch repair protein MutS2
D      E5139_08190 endonuclease MutS2	K07456 mutS2; DNA mismatch repair protein MutS2
D      E5139_05165 mutL; DNA mismatch repair endonuclease MutL	K03572 mutL; DNA mismatch repair protein MutL
D      E5139_05585 DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      E5139_06945 hypothetical protein	K04067 priC; primosomal replication protein N''
D      E5139_01770 DNA double-strand break repair Rad50 ATPase	K03546 sbcC; DNA repair protein SbcC/Rad50
D      E5139_01775 exonuclease SbcCD subunit D	K03547 sbcD; DNA repair protein SbcD/Mre11
D      E5139_16420 exonuclease V subunit beta	K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D      E5139_16415 hypothetical protein	K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D      E5139_01465 cas1b; type I-B CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1
D      E5139_09100 radA; DNA repair and recombination protein RadA	K04483 radA; DNA repair protein RadA
D      E5139_12050 radB; DNA repair and recombination protein RadB	K04484 radB; DNA repair protein RadB
D      E5139_07625 nucleoid-structuring protein H-NS	K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D      E5139_06620 ATP-dependent DNA helicase	K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D      E5139_00955 gyrA; DNA gyrase subunit A	K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D      E5139_00950 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B	K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D      E5139_06510 DUF91 domain-containing protein	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D      E5139_02320 DNA topoisomerase I	K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D      E5139_14970 dinB; DNA polymerase IV	K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D      E5139_02205 polX; DNA polymerase/3'-5' exonuclease PolX	K02347 polX; DNA polymerase (family X)
D      E5139_15250 DEAD/DEAH box helicase	K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D      E5139_13720 ATP-dependent helicase	K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D      E5139_11950 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      E5139_16610 ribonucleoside-diphosphate reductase subunit alpha	K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D      E5139_16615 ribonucleotide reductase	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      E5139_15840 ribonucleoside-diphosphate reductase	K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D      E5139_03910 recombination protein RecJ	K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D      E5139_03190 hypothetical protein	K22585 nreA; DNA repair protein NreA
C    03029 Mitochondrial biogenesis [BR:halz03029]
D      E5139_12300 ribonuclease P protein component 1	K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D      E5139_15130 ribonuclease P	K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D      E5139_15115 ribonuclease P	K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D      E5139_07235 GTP-binding protein	K03595 era; GTPase
D      E5139_00090 tyrosine--tRNA ligase	K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D      E5139_07665 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_06585 leucine--tRNA ligase	K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D      E5139_07150 glyS; glycine--tRNA ligase	K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D      E5139_09615 arginine--tRNA ligase	K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D      E5139_13085 gatA; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D      E5139_02295 gatB; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D      E5139_13080 gatC; Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D      E5139_01505 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK
D      E5139_16085 grpE; nucleotide exchange factor GrpE	K04043 dnaK; molecular chaperone DnaK
D      E5139_01500 grpE; nucleotide exchange factor GrpE	K03687 GRPE; molecular chaperone GrpE
D      E5139_01525 dnaJ; molecular chaperone DnaJ	K03686 dnaJ; molecular chaperone DnaJ
D      E5139_15815 molecular chaperone DnaJ	K03686 dnaJ; molecular chaperone DnaJ
D      E5139_13390 glutaredoxin	K07390 grxD; monothiol glutaredoxin
D      E5139_10950 Mrp/NBP35 family ATP-binding protein	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      E5139_15455 DUF2249 domain-containing protein	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      E5139_00210 Mrp/NBP35 family ATP-binding protein	K03593 mrp; ATP-binding protein involved in chromosome partitioning
D      E5139_01280 cyoE; protoheme IX farnesyltransferase	K02257 COX10; heme o synthase [EC:2.5.1.141]
D      E5139_11905 cytochrome oxidase assembly	K02259 COX15; heme a synthase [EC:1.17.99.9]
B
B  09183 Protein families: signaling and cellular processes
C    02000 Transporters [BR:halz02000]
D      E5139_10430 ABC transporter ATP-binding protein	K11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]
D      E5139_05280 ABC transporter ATP-binding protein	K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D      E5139_05350 ABC transporter ATP-binding protein	K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D      E5139_10185 sulfate ABC transporter substrate-binding protein	K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D      E5139_10180 ABC transporter permease subunit	K15496 wtpB; molybdate/tungstate transport system permease protein
D      E5139_10175 ABC transporter ATP-binding protein	K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D      E5139_14530 extracellular solute-binding protein	K02012 afuA; iron(III) transport system substrate-binding protein
D      E5139_14525 iron ABC transporter permease	K02011 afuB; iron(III) transport system permease protein
D      E5139_14520 ABC transporter ATP-binding protein	K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D      E5139_12780 thiamine ABC transporter substrate-binding protein	K02064 thiB; thiamine transport system substrate-binding protein
D      E5139_12785 iron ABC transporter permease	K02063 thiP; thiamine transport system permease protein
D      E5139_12790 ABC transporter ATP-binding protein	K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D      E5139_15890 extracellular solute-binding protein	K02055 ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein
D      E5139_15895 ABC transporter permease subunit	K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D      E5139_15900 ABC transporter permease subunit	K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D      E5139_15905 ABC transporter ATP-binding protein	K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D      E5139_14480 ABC transporter ATP-binding protein	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_07890 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_12220 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_16010 ABC transporter ATP-binding protein	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_04330 ABC transporter ATP-binding protein	K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D      E5139_04325 extracellular solute-binding protein	K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D      E5139_04320 sugar ABC transporter permease	K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D      E5139_04315 ABC transporter permease subunit	K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D      E5139_00140 extracellular solute-binding protein	K17315 gtsA; glucose/mannose transport system substrate-binding protein
D      E5139_12235 carbohydrate ABC transporter substrate-binding protein	K17315 gtsA; glucose/mannose transport system substrate-binding protein
D      E5139_12230 sugar ABC transporter permease	K17316 gtsB; glucose/mannose transport system permease protein
D      E5139_12225 carbohydrate ABC transporter permease	K17317 gtsC; glucose/mannose transport system permease protein
D      E5139_14465 extracellular solute-binding protein	K10236 thuE; trehalose/maltose transport system substrate-binding protein
D      E5139_14470 sugar ABC transporter permease	K10237 thuF; trehalose/maltose transport system permease protein
D      E5139_14475 carbohydrate ABC transporter permease	K10238 thuG; trehalose/maltose transport system permease protein
D      E5139_15995 extracellular solute-binding protein	K10188 lacE; lactose/L-arabinose transport system substrate-binding protein
D      E5139_16000 sugar ABC transporter permease	K10189 lacF; lactose/L-arabinose transport system permease protein
D      E5139_16005 carbohydrate ABC transporter permease	K10190 lacG; lactose/L-arabinose transport system permease protein
D      E5139_04945 ABC transporter substrate-binding protein	K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
D      E5139_04940 sugar ABC transporter permease	K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein
D      E5139_04935 carbohydrate ABC transporter permease	K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein
D      E5139_04930 ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10]
D      E5139_08250 BMP family ABC transporter substrate-binding protein	K07335 bmpA; basic membrane protein A and related proteins
D      E5139_03105 BMP family ABC transporter substrate-binding protein	K07335 bmpA; basic membrane protein A and related proteins
D      E5139_03115 ABC transporter permease	K23535 nupB; general nucleoside transport system permease protein
D      E5139_03120 ABC transporter permease	K23536 nupC; general nucleoside transport system permease protein
D      E5139_03110 ABC transporter ATP-binding protein	K23537 nupA; general nucleoside transport system ATP-binding protein
D      E5139_07880 sugar ABC transporter substrate-binding protein	K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D      E5139_07875 sugar ABC transporter permease	K02025 ABC.MS.P; multiple sugar transport system permease protein
D      E5139_07870 carbohydrate ABC transporter permease	K02026 ABC.MS.P1; multiple sugar transport system permease protein
D      E5139_12085 PstS family phosphate ABC transporter substrate-binding protein	K02040 pstS; phosphate transport system substrate-binding protein
D      E5139_05070 PstS family phosphate ABC transporter substrate-binding protein	K02040 pstS; phosphate transport system substrate-binding protein
D      E5139_12080 pstC; phosphate ABC transporter permease subunit PstC	K02037 pstC; phosphate transport system permease protein
D      E5139_05065 pstC; phosphate ABC transporter permease subunit PstC	K02037 pstC; phosphate transport system permease protein
D      E5139_12075 pstA; phosphate ABC transporter permease PstA	K02038 pstA; phosphate transport system permease protein
D      E5139_05060 pstA; phosphate ABC transporter permease PstA	K02038 pstA; phosphate transport system permease protein
D      E5139_12070 pstB; phosphate ABC transporter ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      E5139_05055 phosphate ABC transporter ATP-binding protein	K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D      E5139_15775 ABC transporter substrate-binding protein	K01999 livK; branched-chain amino acid transport system substrate-binding protein
D      E5139_15790 branched-chain amino acid ABC transporter permease	K01997 livH; branched-chain amino acid transport system permease protein
D      E5139_15795 branched-chain amino acid ABC transporter permease	K01998 livM; branched-chain amino acid transport system permease protein
D      E5139_15780 ABC transporter ATP-binding protein	K01995 livG; branched-chain amino acid transport system ATP-binding protein
D      E5139_15785 ABC transporter ATP-binding protein	K01996 livF; branched-chain amino acid transport system ATP-binding protein
D      E5139_11585 transporter substrate-binding domain-containing protein	K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D      E5139_11570 amino acid ABC transporter permease	K02029 ABC.PA.P; polar amino acid transport system permease protein
D      E5139_11580 amino acid ABC transporter permease	K02029 ABC.PA.P; polar amino acid transport system permease protein
D      E5139_04380 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_11115 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_09120 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_03570 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_03870 ABC transporter substrate-binding protein	K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D      E5139_04375 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_11110 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_09125 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_03565 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_05830 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_03865 ABC transporter permease	K02033 ABC.PE.P; peptide/nickel transport system permease protein
D      E5139_04370 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_11105 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_09130 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_03560 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_05825 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_03860 ABC transporter permease	K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D      E5139_04385 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_11100 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_09135 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_03555 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_05820 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_03855 ABC transporter ATP-binding protein	K02031 ddpD; peptide/nickel transport system ATP-binding protein
D      E5139_05815 ATP-binding cassette domain-containing protein	K02032 ddpF; peptide/nickel transport system ATP-binding protein
D      E5139_15325 ABC transporter substrate-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_16560 Fe3+-hydroxamate ABC transporter substrate-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_04680 cobalamin-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_16770 ABC transporter substrate-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_00855 ABC transporter substrate-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_05255 Fe3+-hydroxamate ABC transporter substrate-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_16425 ABC transporter substrate-binding protein	K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D      E5139_15345 iron ABC transporter permease	K02015 ABC.FEV.P; iron complex transport system permease protein
D      E5139_05250 hypothetical protein	K02015 ABC.FEV.P; iron complex transport system permease protein
D      E5139_15340 ABC transporter ATP-binding protein	K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D      E5139_01245 PGF-CTERM sorting domain-containing protein	K25034 btuF; cobalamin transport system substrate-binding protein
D      E5139_01250 btuC; vitamin B12 ABC transporter permease BtuC	K25027 btuC; cobalamin transport system permease protein
D      E5139_01255 ATP-binding cassette domain-containing protein	K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]
D      E5139_16440 zinc ABC transporter substrate-binding protein	K09815 znuA; zinc transport system substrate-binding protein
D      E5139_08215 zinc ABC transporter substrate-binding protein	K09815 znuA; zinc transport system substrate-binding protein
D      E5139_16450 metal ABC transporter permease	K09816 znuB; zinc transport system permease protein
D      E5139_08205 metal ABC transporter permease	K09816 znuB; zinc transport system permease protein
D      E5139_16445 metal ABC transporter ATP-binding protein	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      E5139_08210 metal ABC transporter ATP-binding protein	K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D      E5139_04770 metal transporter	K02009 cbiN; cobalt/nickel transport protein
D      E5139_04765 cbiQ; cobalt ECF transporter T component CbiQ	K02008 cbiQ; cobalt/nickel transport system permease protein
D      E5139_04775 metal transporter	K02007 cbiM; cobalt/nickel transport system permease protein
D      E5139_04760 energy-coupling factor ABC transporter ATP-binding protein	K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D      E5139_05660 BioY family transporter	K03523 bioY; biotin transport system substrate-specific component
D      E5139_05650 energy-coupling factor transporter transmembrane protein EcfT	K16783 bioN; biotin transport system permease protein
D      E5139_05655 ABC transporter ATP-binding protein	K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D      E5139_05030 hypothetical protein	K19341 nosY; Cu-processing system permease protein
D      E5139_05040 copper-binding protein	K07218 nosD; nitrous oxidase accessory protein
D      E5139_05035 ABC transporter ATP-binding protein	K19340 nosF; Cu-processing system ATP-binding protein
D      E5139_01305 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_02390 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_06235 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_08590 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_06575 hypothetical protein	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_07120 hypothetical protein	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_07130 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_07520 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_00835 ABC transporter permease	K01992 ABC-2.P; ABC-2 type transport system permease protein
D      E5139_01985 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_07535 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_01300 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_02385 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_06570 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_06240 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_07115 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_07125 ATP-binding cassette domain-containing protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_08585 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_00805 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_00845 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_15745 ABC transporter ATP-binding protein	K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D      E5139_10730 ABC transporter permease	K02004 ABC.CD.P; putative ABC transport system permease protein
D      E5139_03295 ABC transporter permease	K02004 ABC.CD.P; putative ABC transport system permease protein
D      E5139_10725 ABC transporter ATP-binding protein	K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D      E5139_03300 ABC transporter ATP-binding protein	K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D      E5139_03620 ABC transporter ATP-binding protein	K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D      E5139_01865 ABC transporter ATP-binding protein	K09013 sufC; Fe-S cluster assembly ATP-binding protein
D      E5139_06605 MATE family efflux transporter	K26937 dinF; MATE family, multidrug efflux pump
D      E5139_06715 MATE family efflux transporter	K26937 dinF; MATE family, multidrug efflux pump
D      E5139_16555 MATE family efflux transporter	K26937 dinF; MATE family, multidrug efflux pump
D      E5139_12155 MATE family efflux transporter	K26937 dinF; MATE family, multidrug efflux pump
D      E5139_11085 MFS transporter	K05820 hcaT; MFS transporter, PPP family, 3-phenylpropionic acid transporter
D      E5139_11220 MFS transporter	K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein
D      E5139_15705 aquaporin family protein	K02440 glpF; glycerol uptake facilitator
D      E5139_10770 potassium channel protein	K10716 kch; voltage-gated potassium channel
D      E5139_11075 potassium channel protein	K10716 kch; voltage-gated potassium channel
D      E5139_07780 ammonium transporter	K03320 amt; ammonium transporter, Amt family
D      E5139_02840 VWA domain-containing protein	K07114 yfbK; Ca-activated chloride channel homolog
D      E5139_11355 mechanosensitive ion channel family protein	K05802 mscK; potassium-dependent mechanosensitive channel
D      E5139_13120 mechanosensitive ion channel family protein	K03442 mscS; small conductance mechanosensitive channel
D      E5139_13915 mechanosensitive ion channel family protein	K03442 mscS; small conductance mechanosensitive channel
D      E5139_06095 mechanosensitive ion channel	K22044 ybiO; moderate conductance mechanosensitive channel
D      E5139_09455 hypothetical protein	K07244 K07244; mgtE-like transporter
D      E5139_09460 ABC transporter permease	K07244 K07244; mgtE-like transporter
D      E5139_14050 corA; magnesium/cobalt transporter CorA	K03284 corA; magnesium transporter
D      E5139_05725 crcB; fluoride efflux transporter CrcB	K06199 crcB; fluoride exporter
D      E5139_05730 crcB; fluoride efflux transporter CrcB	K06199 crcB; fluoride exporter
D      E5139_07595 HlyC/CorC family transporter	K03699 tlyC; magnesium and cobalt exporter, CNNM family
D      E5139_06980 HlyC/CorC family transporter	K03699 tlyC; magnesium and cobalt exporter, CNNM family
D      E5139_06065 pyrrolo-quinoline quinone	K17713 bamB; outer membrane protein assembly factor BamB
D      E5139_10635 pyrrolo-quinoline quinone	K17713 bamB; outer membrane protein assembly factor BamB
D      E5139_11825 pyrrolo-quinoline quinone	K17713 bamB; outer membrane protein assembly factor BamB
D      E5139_12130 hypothetical protein	K17713 bamB; outer membrane protein assembly factor BamB
D      E5139_05620 hypothetical protein	K21449 ata; trimeric autotransporter adhesin
D      E5139_09955 ZIP family metal transporter	K07238 TC.ZIP; zinc transporter, ZIP family
D      E5139_09355 ZIP family metal transporter	K07238 TC.ZIP; zinc transporter, ZIP family
D      E5139_05310 ZIP family metal transporter	K07238 TC.ZIP; zinc transporter, ZIP family
D      E5139_14165 multidrug efflux SMR transporter	K03297 emrE; small multidrug resistance pump
D      E5139_01945 sodium:calcium antiporter	K07301 yrbG; cation:H+ antiporter
D      E5139_10250 sodium:calcium antiporter	K07301 yrbG; cation:H+ antiporter
D      E5139_16160 inorganic phosphate transporter	K16331 ylnA; sulfate permease
D      E5139_09290 cation acetate symporter	K14393 actP; cation/acetate symporter
D      E5139_07165 potassium transporter TrkA	K07228 khtT; K+:H+ antiporter subunit KhtT
D      E5139_07160 cation:proton antiporter	K26732 khtU; K+:H+ antiporter subunit KhtU
D      E5139_12500 TrkH family potassium uptake protein	K03498 trkH; trk/ktr system potassium uptake protein
D      E5139_11140 TrkA family potassium uptake protein	K03499 trkA; trk/ktr system potassium uptake protein
D      E5139_09095 TrkA family potassium uptake protein	K03499 trkA; trk/ktr system potassium uptake protein
D      E5139_12505 trkA; Trk system potassium transporter TrkA	K03499 trkA; trk/ktr system potassium uptake protein
D      E5139_07420 NCS2 family permease	K06901 pbuG; adenine/guanine/hypoxanthine permease
D      E5139_09925 divalent metal cation transporter	K03322 mntH; manganese transport protein
D      E5139_02130 ArsA family ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      E5139_16575 arsenic-transporting ATPase	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D      E5139_12165 arsB; ACR3 family arsenite efflux transporter	K03325 ACR3; arsenite transporter
D      E5139_01575 DUF4040 domain-containing protein	K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D      E5139_01580 cation:proton antiporter	K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D      E5139_01585 cation:proton antiporter	K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D      E5139_01590 monovalent cation/H+ antiporter subunit D family protein	K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D      E5139_01595 monovalent cation/H+ antiporter subunit D family protein	K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D      E5139_01600 Na(+)/H(+) antiporter subunit D	K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D      E5139_01560 monovalent cation/H+ antiporter subunit E	K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D      E5139_01565 cation:proton antiporter	K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D      E5139_01570 monovalent cation/H(+) antiporter subunit G	K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D      E5139_05290 AEC family transporter	K13936 mdcF; malonate transporter and related proteins
D      E5139_02270 AEC family transporter	K24180 mleP; malate permease and related proteins
D      E5139_16635 AzlD domain-containing protein	K26606 azlD; branched chain amino acid efflux pump
D      E5139_03400 TMEM165/GDT1 family protein	K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D      E5139_06630 hypothetical protein	K08970 rcnA; nickel/cobalt transporter (NicO) family protein
D      E5139_15485 nitrate reductase	K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D      E5139_15480 respiratory nitrate reductase subunit beta	K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D      E5139_16210 dimethyl sulfoxide reductase	K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D      E5139_16205 4Fe-4S dicluster domain-containing protein	K00184 dmsB; dimethyl sulfoxide reductase iron-sulfur subunit
D      E5139_16200 molybdopterin oxidoreductase	K00185 dmsC; dimethyl sulfoxide reductase membrane subunit
D      E5139_09160 tryptophan-rich sensory protein	K05770 TSPO; translocator protein
C    02044 Secretion system [BR:halz02044]
D      E5139_04495 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_04500 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_04505 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_15610 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_04460 flagella E	K23986 flaCE; archaeal flagellar protein FlaCE
D      E5139_04455 flagellin	K07329 flaF; archaeal flagellar protein FlaF
D      E5139_04450 flagellar protein G	K07330 flaG; archaeal flagellar protein FlaG
D      E5139_04445 ATPase	K07331 flaH; archaeal flagellar protein FlaH
D      E5139_13885 secretion system protein	K07332 flaI; archaeal flagellar protein FlaI
D      E5139_00910 type II secretion system protein	K07332 flaI; archaeal flagellar protein FlaI
D      E5139_02545 type II secretion protein	K07332 flaI; archaeal flagellar protein FlaI
D      E5139_04435 flaJ; archaellar assembly protein FlaJ	K07333 flaJ; archaeal flagellar protein FlaJ
D      E5139_13880 flagella assembly protein j	K07333 flaJ; archaeal flagellar protein FlaJ
D      E5139_00915 type II secretion system protein	K07333 flaJ; archaeal flagellar protein FlaJ
D      E5139_07455 prepilin peptidase	K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D      E5139_09770 preprotein translocase subunit SecD	K03072 secD; preprotein translocase subunit SecD
D      E5139_09765 protein translocase subunit SecF	K03074 secF; preprotein translocase subunit SecF
D      E5139_12375 secY; preprotein translocase subunit SecY	K03076 secY; preprotein translocase subunit SecY
D      E5139_09305 signal recognition particle protein	K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D      E5139_09320 ftsY; signal recognition particle-docking protein FtsY	K03110 ftsY; fused signal recognition particle receptor
D      E5139_01965 protein translocase SEC61 complex subunit gamma	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D      E5139_01240 signal recognition particle protein Srp19	K03105 SRP19; signal recognition particle subunit SRP19
D      E5139_00715 twin-arginine translocase TatA/TatE family subunit	K03116 tatA; sec-independent protein translocase protein TatA
D      E5139_08145 preprotein translocase subunit TatC	K03118 tatC; sec-independent protein translocase protein TatC
D      E5139_08150 preprotein translocase subunit TatC	K03118 tatC; sec-independent protein translocase protein TatC
C    02042 Bacterial toxins [BR:halz02042]
D      E5139_07595 HlyC/CorC family transporter	K03699 tlyC; magnesium and cobalt exporter, CNNM family
D      E5139_06980 HlyC/CorC family transporter	K03699 tlyC; magnesium and cobalt exporter, CNNM family
C    02022 Two-component system [BR:halz02022]
D      E5139_06285 histidine kinase	K07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]
D      E5139_08155 HAMP domain-containing histidine kinase	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_04215 histidine kinase	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_13470 PAS domain S-box protein	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_14285 two-component sensor histidine kinase	K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D      E5139_06835 response regulator	K02483 K02483; two-component system, OmpR family, response regulator
D      E5139_04535 chemotaxis protein CheA	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      E5139_04475 response regulator	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      E5139_04530 chemotaxis response regulator protein-glutamate methylesterase	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C    02035 Bacterial motility proteins [BR:halz02035]
D      E5139_04535 chemotaxis protein CheA	K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D      E5139_04525 purine-binding chemotaxis protein CheW	K03408 cheW; purine-binding chemotaxis protein CheW
D      E5139_04470 chemotaxis protein CheA	K03410 cheC; chemotaxis protein CheC
D      E5139_07765 chemotaxis protein CheC	K03410 cheC; chemotaxis protein CheC
D      E5139_13925 chemotaxis protein CheC	K03410 cheC; chemotaxis protein CheC
D      E5139_15010 chemotaxis protein CheC	K03410 cheC; chemotaxis protein CheC
D      E5139_04465 chemotaxis protein CheD	K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D      E5139_04540 protein-glutamate O-methyltransferase CheR	K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D      E5139_04530 chemotaxis response regulator protein-glutamate methylesterase	K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D      E5139_04475 response regulator	K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D      E5139_15715 extracellular solute-binding protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_15245 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_02420 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_15430 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11295 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11325 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_02805 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_11900 PAS domain-containing protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_08245 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_04690 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_00695 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_14420 methyl-accepting chemotaxis protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_08610 HAMP domain-containing protein	K03406 mcp; methyl-accepting chemotaxis protein
D      E5139_16745 globin-coupled sensor protein	K06595 hemAT; heam-based aerotactic trancducer
D      E5139_04495 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_04500 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_04505 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_15610 flagellin	K07325 flaB; archaeal flagellin FlaB
D      E5139_04460 flagella E	K23986 flaCE; archaeal flagellar protein FlaCE
D      E5139_04455 flagellin	K07329 flaF; archaeal flagellar protein FlaF
D      E5139_04450 flagellar protein G	K07330 flaG; archaeal flagellar protein FlaG
D      E5139_04445 ATPase	K07331 flaH; archaeal flagellar protein FlaH
D      E5139_13885 secretion system protein	K07332 flaI; archaeal flagellar protein FlaI
D      E5139_00910 type II secretion system protein	K07332 flaI; archaeal flagellar protein FlaI
D      E5139_02545 type II secretion protein	K07332 flaI; archaeal flagellar protein FlaI
D      E5139_04435 flaJ; archaellar assembly protein FlaJ	K07333 flaJ; archaeal flagellar protein FlaJ
D      E5139_13880 flagella assembly protein j	K07333 flaJ; archaeal flagellar protein FlaJ
D      E5139_00915 type II secretion system protein	K07333 flaJ; archaeal flagellar protein FlaJ
D      E5139_07455 prepilin peptidase	K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C    03037 Cilium and associated proteins
C    04812 Cytoskeleton proteins [BR:halz04812]
D      E5139_01955 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      E5139_04145 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      E5139_05740 cell division protein	K22222 cetZ; tubulin-like protein CetZ
D      E5139_10215 cell division protein	K22222 cetZ; tubulin-like protein CetZ
D      E5139_02560 cell division protein	K22222 cetZ; tubulin-like protein CetZ
D      E5139_14635 cobyrinic acid ac-diamide synthase	K03609 minD; septum site-determining protein MinD
D      E5139_03975 chromosome partitioning protein ParA	K03609 minD; septum site-determining protein MinD
D      E5139_08410 chromosome partitioning protein ParA	K03609 minD; septum site-determining protein MinD
D      E5139_09610 septum site-determining protein MinD	K03609 minD; septum site-determining protein MinD
D      E5139_12825 ParA family protein	K03496 parA; chromosome partitioning protein
C    04147 Exosome [BR:halz04147]
D      E5139_00275 phosphopyruvate hydratase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D      E5139_06445 gap; type I glyceraldehyde-3-phosphate dehydrogenase	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D      E5139_05800 phosphoglycerate kinase	K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D      E5139_15690 pyk; pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40]
D      E5139_11080 peptidylprolyl isomerase	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D      E5139_05605 tuf; translation elongation factor EF-1 subunit alpha	K03231 EEF1A; elongation factor 1-alpha
D      E5139_12180 GTP-binding protein	K03231 EEF1A; elongation factor 1-alpha
D      E5139_05640 elongation factor EF-2	K03234 EEF2; elongation factor 2
D      E5139_01505 dnaK; molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK
D      E5139_16085 grpE; nucleotide exchange factor GrpE	K04043 dnaK; molecular chaperone DnaK
D      E5139_09750 glucose-6-phosphate isomerase	K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D      E5139_01190 flap endonuclease-1	K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D      E5139_14915 guaB; IMP dehydrogenase	K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D      E5139_09035 30S ribosomal protein S27ae	K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D      E5139_12020 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_13590 AAA family ATPase	K13525 VCP; transitional endoplasmic reticulum ATPase
D      E5139_08430 HIT family protein	K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D      E5139_01335 3-ketoacyl-CoA thiolase	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_14560 thiolase family protein	K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D      E5139_06960 adenosylhomocysteinase	K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D      E5139_11805 adenylate kinase	K00939 adk; adenylate kinase [EC:2.7.4.3]
D      E5139_01630 purine phosphoribosyltransferase family protein	K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D      E5139_07035 argH; argininosuccinate lyase	K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D      E5139_07030 argininosuccinate synthase	K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D      E5139_01835 class 1 fructose-bisphosphatase	K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D      E5139_15710 glpK; glycerol kinase GlpK	K00864 glpK; glycerol kinase [EC:2.7.1.30]
D      E5139_06725 glnA; type I glutamate--ammonia ligase	K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D      E5139_07790 hemB; porphobilinogen synthase	K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D      E5139_11185 4a-hydroxytetrahydrobiopterin dehydratase	K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D      E5139_07140 phosphoglycerate dehydrogenase	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_04290 C-terminal binding protein	K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D      E5139_08085 lpdA; dihydrolipoyl dehydrogenase	K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D      E5139_09510 electron transfer flavoprotein subunit alpha/FixB family protein	K03522 fixB; electron transfer flavoprotein alpha subunit
D      E5139_02815 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_02910 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_16755 Glu/Leu/Phe/Val dehydrogenase	K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D      E5139_14980 tpiA; triose-phosphate isomerase	K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C    02048 Prokaryotic defense system [BR:halz02048]
D      E5139_01465 cas1b; type I-B CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1
D      E5139_01470 cas2; CRISPR-associated endonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2
D      E5139_01455 CRISPR-associated endonuclease Cas3''	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D      E5139_01460 Dna2/Cas4 domain-containing protein	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D      E5139_07615 hypothetical protein	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D      E5139_01435 cas6; CRISPR-associated endoribonuclease Cas6	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D      E5139_01445 cas7b; type I-B CRISPR-associated protein Cas7/Csh2	K19115 csh2; CRISPR-associated protein Csh2
D      E5139_01450 cas5b; type I-B CRISPR-associated protein Cas5	K19116 cas5h; CRISPR-associated protein Cas5h
D      E5139_05585 DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D      E5139_05510 DNA cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D      E5139_02425 site-specific DNA-methyltransferase	K24451 zim; modification methylase
D      E5139_02345 AAA family ATPase	K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]
D      E5139_16360 restriction endonuclease	K07448 mrr; restriction system protein
D      E5139_05085 type II toxin-antitoxin system PemK/MazF family toxin	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D      E5139_00880 type II toxin-antitoxin system PemK/MazF family toxin	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D      E5139_11005 type II toxin-antitoxin system RelE/ParE family toxin	K06218 relE; mRNA interferase RelE/StbE
D      E5139_08950 type II toxin-antitoxin system RelE/ParE family toxin	K06218 relE; mRNA interferase RelE/StbE
D      E5139_16365 Fic family protein	K07341 doc; death on curing protein
D      E5139_03610 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D      E5139_00050 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D      E5139_04630 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D      E5139_01955 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      E5139_04145 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ
D      E5139_00330 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D      E5139_09735 NOB1 family endonuclease	K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C    04030 G protein-coupled receptors [BR:halz04030]
D      E5139_09580 rhodopsin	K04641 bop; bacteriorhodopsin
D      E5139_00690 sensory rhodopsin-2	K04643 sop; sensory rhodopsin
D      E5139_08605 rhodopsin	K04643 sop; sensory rhodopsin
C    04050 Cytokine receptors
C    04054 Pattern recognition receptors
C    03310 Nuclear receptors
C    04040 Ion channels
C    04031 GTP-binding proteins
C    04052 Cytokines and neuropeptides
C    04515 Cell adhesion molecules
C    04090 CD molecules
C    01504 Antimicrobial resistance genes [BR:halz01504]
C    00535 Proteoglycans
C    00536 Glycosaminoglycan binding proteins
C    00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C    04091 Lectins
C    04990 Domain-containing proteins not elsewhere classified
B
B  09185 Viral protein families
C    03200 Viral proteins
C    03210 Viral fusion proteins
B
B  09184 RNA family
C    03100 Non-coding RNAs [BR:halz03100]
D      E5139_13845 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      E5139_06465 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      E5139_05595 tRNA-Ala	K14218 tRNA-Ala; tRNA Ala
D      E5139_07910 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_05980 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_00720 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_13155 tRNA-Arg	K14219 tRNA-Arg; tRNA Arg
D      E5139_05950 tRNA-Asn	K14220 tRNA-Asn; tRNA Asn
D      E5139_05705 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      E5139_05710 tRNA-Asp	K14221 tRNA-Asp; tRNA Asp
D      E5139_06450 tRNA-Cys	K14222 tRNA-Cys; tRNA Cys
D      E5139_01910 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      E5139_07685 tRNA-Gln	K14223 tRNA-Gln; tRNA Gln
D      E5139_13465 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      E5139_00015 tRNA-Glu	K14224 tRNA-Glu; tRNA Glu
D      E5139_12245 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      E5139_00100 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      E5139_06645 tRNA-Gly	K14225 tRNA-Gly; tRNA Gly
D      E5139_08315 tRNA-His	K14226 tRNA-His; tRNA His
D      E5139_11020 tRNA-Ile	K14227 tRNA-Ile; tRNA Ile
D      E5139_13550 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_11120 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_14255 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_00245 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_14355 tRNA-Leu	K14228 tRNA-Leu; tRNA Leu
D      E5139_05860 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      E5139_15060 tRNA-Lys	K14229 tRNA-Lys; tRNA Lys
D      E5139_01635 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      E5139_05945 tRNA-Met	K14230 tRNA-Met; tRNA Met
D      E5139_06325 tRNA-Phe	K14231 tRNA-Phe; tRNA Phe
D      E5139_08350 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      E5139_11785 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      E5139_10410 tRNA-Pro	K14232 tRNA-Pro; tRNA Pro
D      E5139_00220 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_00460 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_03485 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_07360 tRNA-Ser	K14233 tRNA-Ser; tRNA Ser
D      E5139_08960 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      E5139_00430 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      E5139_12885 tRNA-Thr	K14234 tRNA-Thr; tRNA Thr
D      E5139_13545 tRNA-Trp	K14235 tRNA-Trp; tRNA Trp
D      E5139_04130 tRNA-Tyr	K14236 tRNA-Tyr; tRNA Tyr
D      E5139_11980 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      E5139_05365 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      E5139_12760 tRNA-Val	K14237 tRNA-Val; tRNA Val
D      E5139_16035 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_06470 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_13370 16S ribosomal RNA	K01977 16SrRNA; 16S ribosomal RNA
D      E5139_13375 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_06460 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_16030 23S ribosomal RNA	K01980 23SrRNA; 23S ribosomal RNA
D      E5139_13380 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_06455 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_16025 rrf; 5S ribosomal RNA	K01985 5SrRNA; 5S ribosomal RNA
D      E5139_13130 ffs; signal recognition particle sRNA	K01983 ffs; SRP RNA
D      E5139_04595 rnpB; RNase P RNA component	K01978 rnpB; M1 RNA
#
A09190 Not Included in Pathway or Brite
B
B  09191 Unclassified: metabolism
C    99980 Enzymes with EC numbers
D      E5139_06375 aldo/keto reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      E5139_03370 aldo/keto reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      E5139_01515 aldo/keto reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      E5139_15950 aldo/keto reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      E5139_09010 aldo/keto reductase	K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D      E5139_14840 PQQ-dependent sugar dehydrogenase	K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]
D      E5139_14780 PQQ-dependent sugar dehydrogenase	K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]
D      E5139_04915 TIGR03557 family F420-dependent LLM class oxidoreductase	K15510 fgd1; coenzyme F420-dependent glucose-6-phosphate dehydrogenase [EC:1.1.98.2]
D      E5139_08995 aldo/keto reductase	K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D      E5139_00830 aldo/keto reductase	K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D      E5139_04800 npdG; NADPH-dependent F420 reductase	K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D      E5139_00055 NAD(P)/FAD-dependent oxidoreductase	K00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]
D      E5139_00355 flavoprotein	K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D      E5139_13205 NAD/FAD-dependent oxidoreductase	K18208 RNLS; renalase [EC:1.6.3.5]
D      E5139_14090 FAD-dependent oxidoreductase	K18208 RNLS; renalase [EC:1.6.3.5]
D      E5139_06080 NADP-dependent oxidoreductase	K00359 qorA; NADPH:quinone reductase [EC:1.6.5.5]
D      E5139_04245 msrA; peptide-methionine (S)-S-oxide reductase MsrA	K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D      E5139_00410 msrB; peptide-methionine (R)-S-oxide reductase MsrB	K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D      E5139_06415 glutathione S-transferase family protein	K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D      E5139_13610 thioredoxin-dependent thiol peroxidase	K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D      E5139_08065 peroxiredoxin	K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D      E5139_07175 redoxin domain-containing protein	K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D      E5139_02765 redoxin domain-containing protein	K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D      E5139_04965 redoxin domain-containing protein	K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D      E5139_00710 redoxin domain-containing protein	K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D      E5139_07605 redoxin domain-containing protein	K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D      E5139_14955 redoxin domain-containing protein	K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D      E5139_11550 beta-carotene 15,15'-dioxygenase	K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]
D      E5139_09590 brp-like protein 2	K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]
D      E5139_16535 lysine 6-monooxygenase	K27501 alcA; putrescine N-hydroxylase [EC:1.14.13.252]
D      E5139_12170 low molecular weight phosphatase family protein	K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D      E5139_16590 hypothetical protein	K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D      E5139_05745 protein-L-isoaspartate O-methyltransferase	K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D      E5139_05755 protein-L-isoaspartate(D-aspartate) O-methyltransferase	K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D      E5139_12875 diphthine synthase	K20215 dph5; diphthine synthase [EC:2.1.1.98]
D      E5139_15385 GNAT family N-acetyltransferase	K22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57]
D      E5139_08135 sugar O-acetyltransferase	K00661 maa; maltose O-acetyltransferase [EC:2.3.1.79]
D      E5139_09805 deoxyhypusine synthase	K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D      E5139_08855 larB; nickel pincer cofactor biosynthesis protein LarB	K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D      E5139_10320 tRNA-ribosyltransferase	K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D      E5139_10295 TIGR01210 family radical SAM protein	K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D      E5139_14375 diadenylate cyclase	K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D      E5139_04685 moeB; molybdopterin-synthase adenylyltransferase MoeB	K22837 ubaA; SAMP-activating enzyme [EC:2.7.7.100]
D      E5139_14995 CDP-alcohol phosphatidyltransferase family protein	K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D      E5139_04250 acyl-CoA thioesterase	K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D      E5139_06195 DUF91 domain-containing protein	K07503 nucS; endonuclease [EC:3.1.-.-]
D      E5139_15990 glycosyl hydrolase family 88	K18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]
D      E5139_07855 RidA family protein	K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D      E5139_07350 RidA family protein	K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D      E5139_06305 MoxR family ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      E5139_09985 MoxR family ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      E5139_03490 MoxR family ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      E5139_13695 MoxR family ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      E5139_03765 MoxR family ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      E5139_08625 AAA family ATPase	K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D      E5139_03235 S-adenosyl-l-methionine hydroxide adenosyltransferase	K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D      E5139_07095 lanM; type 2 lantipeptide synthetase LanM	K27862 lanM; class II lanthipeptide synthase [EC:3.13.2.4]
D      E5139_15155 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D      E5139_16020 DNRLRE domain-containing protein	K01727 hysA; hyaluronate lyase [EC:4.2.2.1]
D      E5139_08160 larE; ATP-dependent sacrificial sulfur transferase LarE	K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37]
D      E5139_12030 larC; nickel pincer cofactor biosynthesis protein LarC	K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D      E5139_16730 heavy metal translocating P-type ATPase	K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D      E5139_16055 cation-translocating P-type ATPase	K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C    99981 Carbohydrate metabolism
C    99982 Energy metabolism
D      E5139_06615 ferredoxin	K05337 fer; ferredoxin
D      E5139_12460 ferredoxin	K05337 fer; ferredoxin
D      E5139_09435 SUF system NifU family Fe-S cluster assembly protein	K04488 iscU; nitrogen fixation protein NifU and related proteins
D      E5139_16145 AAA family ATPase	K04748 norQ; nitric oxide reductase NorQ protein
D      E5139_15500 (2Fe-2S)-binding protein	K15878 K15878; rieske iron-sulfur protein
D      E5139_15495 cytochrome bc complex cytochrome b subunit	K15879 narC; cytochrome b-561
D      E5139_00345 electron transfer flavoprotein subunit beta/FixA family protein	K03521 fixA; electron transfer flavoprotein beta subunit
D      E5139_09515 electron transfer flavoprotein subunit beta/FixA family protein	K03521 fixA; electron transfer flavoprotein beta subunit
D      E5139_15395 dodecin domain-containing protein	K09165 K09165; dodecin
C    99983 Lipid metabolism
C    99984 Nucleotide metabolism
C    99985 Amino acid metabolism
C    99986 Glycan metabolism
D      E5139_08680 flippase-like domain-containing protein	K07027 K07027; glycosyltransferase 2 family protein
D      E5139_09650 flippase-like domain-containing protein	K07027 K07027; glycosyltransferase 2 family protein
C    99987 Cofactor metabolism
C    99988 Secondary metabolism
C    99999 Others
D      E5139_10400 ring-cleaving dioxygenase	K15975 K15975; glyoxalase family protein
D      E5139_11235 ring-cleaving dioxygenase	K15975 K15975; glyoxalase family protein
D      E5139_14400 DoxX family membrane protein	K15977 K15977; putative oxidoreductase
D      E5139_15630 phospholipase	K06999 K06999; phospholipase/carboxylesterase
D      E5139_10405 phospholipase	K06999 K06999; phospholipase/carboxylesterase
B
B  09192 Unclassified: genetic information processing
C    99973 Transcription
D      E5139_14990 TIGR00270 family protein	K03627 MBF1; putative transcription factor
D      E5139_06390 cold-shock protein	K03704 cspA; cold shock protein
D      E5139_10870 cold-shock protein	K03704 cspA; cold shock protein
D      E5139_10875 cold-shock protein	K03704 cspA; cold shock protein
D      E5139_04980 cold-shock protein	K03704 cspA; cold shock protein
D      E5139_09790 cold-shock protein	K03704 cspA; cold shock protein
D      E5139_13630 Like-Sm ribonucleoprotein core	K04796 RUXX; small nuclear ribonucleoprotein
D      E5139_02670 transcriptional regulator	K07743 K07743; transcriptional regulator
D      E5139_09020 HTH domain-containing protein	K07744 K07744; transcriptional regulator
D      E5139_00975 HTH domain-containing protein	K07744 K07744; transcriptional regulator
C    99974 Translation
D      E5139_00650 DUF655 domain-containing protein	K07572 K07572; putative nucleotide binding protein
D      E5139_05175 MBL fold metallo-hydrolase	K07577 K07577; putative mRNA 3-end processing factor
D      E5139_01730 MBL fold metallo-hydrolase	K07577 K07577; putative mRNA 3-end processing factor
D      E5139_15565 methyltransferase domain-containing protein	K07579 K07579; putative methylase
D      E5139_00670 DUF1610 domain-containing protein	K07580 K07580; Zn-ribbon RNA-binding protein
D      E5139_15110 RNA-binding protein	K07581 K07581; RNA-binding protein
D      E5139_09665 alpha hydrolase	K07585 K07585; tRNA methyltransferase
C    99975 Protein processing
D      E5139_12795 hydrogenase expression protein	K04655 hypE; hydrogenase expression/formation protein HypE
D      E5139_03140 pseudouridine synthase	K07398 K07398; conserved protein with predicted RNA binding PUA domain
D      E5139_07705 NifU family protein	K07400 nfuA; Fe/S biogenesis protein NfuA
D      E5139_01295 SelT/SelW/SelH family protein	K07401 K07401; selenoprotein W-related protein
C    99976 Replication and repair
D      E5139_08860 GIY-YIG nuclease family protein	K07461 K07461; putative endonuclease
D      E5139_01480 IS200/IS605-like element ISHmu6 family transposase	K07491 rayT; REP-associated tyrosine transposase
D      E5139_00510 IS200/IS605-like element ISHmu5 family transposase	K07491 rayT; REP-associated tyrosine transposase
D      E5139_06010 IS200/IS605-like element ISHmu3 family transposase	K07491 rayT; REP-associated tyrosine transposase
D      E5139_01475 transposase	K07496 K07496; putative transposase
D      E5139_13340 transposase	K07496 K07496; putative transposase
D      E5139_06000 transposase	K07496 K07496; putative transposase
D      E5139_14855 transposase	K07496 K07496; putative transposase
D      E5139_11480 transposase	K07496 K07496; putative transposase
D      E5139_16350 transposase	K07496 K07496; putative transposase
D      E5139_12840 transposase	K07496 K07496; putative transposase
D      E5139_00515 transposase	K07496 K07496; putative transposase
D      E5139_03650 IS6-like element ISHmu2 family transposase	K07498 K07498; putative transposase
C    99979 Viral proteins
C    99998 Others
D      E5139_11945 PspA/IM30 family protein	K03969 pspA; phage shock protein A
D      E5139_10115 PspA/IM30 family protein	K03969 pspA; phage shock protein A
B
B  09193 Unclassified: signaling and cellular processes
C    99977 Transport
D      E5139_11495 formate transporter	K21990 yfdC; formate-nitrite transporter family protein
D      E5139_08540 amino acid permease	K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D      E5139_07465 inorganic phosphate transporter	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      E5139_07590 inorganic phosphate transporter	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      E5139_16800 inorganic phosphate transporter	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      E5139_07675 inorganic phosphate transporter	K03306 TC.PIT; inorganic phosphate transporter, PiT family
D      E5139_10830 sodium:solute symporter family protein	K03307 TC.SSS; solute:Na+ symporter, SSS family
D      E5139_00120 sodium-dependent transporter	K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D      E5139_03840 sodium-dependent transporter	K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D      E5139_15355 Na+-dependent transporter	K03453 TC.BASS; bile acid:Na+ symporter, BASS family
C    99978 Cell growth
D      E5139_14310 AbrB family transcriptional regulator	K06415 spoVR; stage V sporulation protein R
C    99993 Cell motility
D      E5139_04550 chemotaxis protein CheF1	K09156 cheF; taxis protein CheF
D      E5139_04555 hypothetical protein	K09156 cheF; taxis protein CheF
D      E5139_11260 hypothetical protein	K09156 cheF; taxis protein CheF
D      E5139_11265 chemotaxis protein CheF1	K09156 cheF; taxis protein CheF
D      E5139_06410 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      E5139_01605 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      E5139_01615 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      E5139_05325 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      E5139_10820 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      E5139_15525 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
D      E5139_09530 type IV pilin	K23255 pilA; archaeal type IV pilus assembly protein PilA
C    99995 Signaling proteins
D      E5139_14295 serine protein kinase PrkA	K07180 prkA; serine protein kinase
D      E5139_11430 KaiC domain-containing protein	K08482 kaiC; circadian clock protein KaiC
D      E5139_09660 DNA-binding protein	K06875 PDCD5; programmed cell death protein 5
C    99992 Structural proteins
D      E5139_12865 PGF-CTERM sorting domain-containing protein	K26284 csg; S-layer glycoprotein
C    99994 Others
D      E5139_12055 phoU; phosphate signaling complex protein PhoU	K02039 phoU; phosphate transport system protein
D      E5139_12060 phoU; phosphate signaling complex protein PhoU	K02039 phoU; phosphate transport system protein
D      E5139_05040 copper-binding protein	K07218 nosD; nitrous oxidase accessory protein
D      E5139_15645 molybdopterin biosynthesis protein	K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D      E5139_05020 nitrous oxide reductase accessory protein NosL	K19342 nosL; copper chaperone NosL
B
B  09194 Poorly characterized
C    99996 General function prediction only
D      E5139_04790 PIN domain-containing protein	K06865 K06865; ATPase
D      E5139_11500 DEAD/DEAH box helicase	K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D      E5139_06380 group 1 truncated hemoglobin	K06886 glbN; hemoglobin
D      E5139_10475 HAD family hydrolase	K07025 K07025; putative hydrolase of the HAD superfamily
D      E5139_09485 HAD family hydrolase	K07025 K07025; putative hydrolase of the HAD superfamily
D      E5139_01870 sufB; Fe-S cluster assembly protein SufB	K09014 sufB; Fe-S cluster assembly protein SufB
D      E5139_16045 sufB; Fe-S cluster assembly protein SufB	K09014 sufB; Fe-S cluster assembly protein SufB
D      E5139_01875 sufD; Fe-S cluster assembly protein SufD	K09015 sufD; Fe-S cluster assembly protein SufD
D      E5139_12510 deoxyribonuclease	K07049 K07049; TatD-related deoxyribonuclease
D      E5139_07500 YihY/virulence factor BrkB family protein	K07058 K07058; membrane protein
D      E5139_15360 YihY/virulence factor BrkB family protein	K07058 K07058; membrane protein
D      E5139_03050 phosphoribosyltransferase	K07100 K07100; putative phosphoribosyl transferase
D      E5139_11025 fxsA; membrane protein FxsA	K07113 fxsA; UPF0716 protein FxsA
D      E5139_14055 hypothetical protein	K08971 K08971; putative membrane protein
D      E5139_04735 DUF368 domain-containing protein	K08974 K08974; putative membrane protein
D      E5139_07900 DUF373 family protein	K08975 K08975; putative membrane protein
D      E5139_01410 DUF373 family protein	K08975 K08975; putative membrane protein
D      E5139_01310 DUF420 domain-containing protein	K08976 K08976; putative membrane protein
D      E5139_13615 DUF420 domain-containing protein	K08976 K08976; putative membrane protein
D      E5139_03475 DUF2070 family protein	K08979 K08979; putative membrane protein
D      E5139_13710 hypothetical protein	K08981 K08981; putative membrane protein
D      E5139_16490 hypothetical protein	K08982 K08982; putative membrane protein
C    99997 Function unknown
D      E5139_01420 proteasome assembly chaperone family protein	K06869 K06869; uncharacterized protein
D      E5139_14595 phosphotransacetylase family protein	K06873 K06873; uncharacterized protein
D      E5139_00165 HD domain-containing protein	K06885 K06885; uncharacterized protein
D      E5139_11030 thioredoxin domain-containing protein	K06888 K06888; uncharacterized protein
D      E5139_14705 thioredoxin domain-containing protein	K06888 K06888; uncharacterized protein
D      E5139_13450 ATP-binding protein	K06921 K06921; uncharacterized protein
D      E5139_13145 CoA-binding protein	K06929 K06929; uncharacterized protein
D      E5139_07000 DNA-binding protein	K06934 K06934; uncharacterized protein
D      E5139_03275 YkgJ family cysteine cluster protein	K06940 K06940; uncharacterized protein
D      E5139_09950 hypothetical protein	K06940 K06940; uncharacterized protein
D      E5139_02650 HD domain-containing protein	K06950 K06950; uncharacterized protein
D      E5139_15230 metallophosphoesterase	K06953 K06953; uncharacterized protein
D      E5139_01395 metallophosphoesterase	K06953 K06953; uncharacterized protein
D      E5139_13910 BtpA/SgcQ family protein	K06971 K06971; uncharacterized protein
D      E5139_13515 succinylglutamate desuccinylase/aspartoacylase family protein	K06987 K06987; uncharacterized protein
D      E5139_07380 succinylglutamate desuccinylase/aspartoacylase family protein	K06987 K06987; uncharacterized protein
D      E5139_15435 pyridoxamine 5'-phosphate oxidase family protein	K07005 K07005; uncharacterized protein
D      E5139_15920 pyridoxamine 5'-phosphate oxidase family protein	K07005 K07005; uncharacterized protein
D      E5139_15370 pyridoxamine 5'-phosphate oxidase family protein	K07005 K07005; uncharacterized protein
D      E5139_10120 alpha/beta hydrolase	K07018 K07018; uncharacterized protein
D      E5139_13395 beta-CASP ribonuclease aCPSF1	K07041 K07041; uncharacterized protein
D      E5139_02885 beta-CASP ribonuclease aCPSF1	K07041 K07041; uncharacterized protein
D      E5139_03250 amidohydrolase	K07045 K07045; uncharacterized protein
D      E5139_11675 PIN domain-containing protein	K07065 K07065; uncharacterized protein
D      E5139_16105 PIN domain-containing protein	K07065 K07065; uncharacterized protein
D      E5139_07575 TAXI family TRAP transporter solute-binding subunit	K07080 K07080; uncharacterized protein
D      E5139_02035 permease	K07089 K07089; uncharacterized protein
D      E5139_15650 permease	K07089 K07089; uncharacterized protein
D      E5139_12775 sulfite exporter TauE/SafE family protein	K07090 K07090; uncharacterized protein
D      E5139_05780 metallophosphoesterase family protein	K07095 K07095; uncharacterized protein
D      E5139_05010 metallophosphoesterase family protein	K07095 K07095; uncharacterized protein
D      E5139_07295 metallophosphoesterase	K07095 K07095; uncharacterized protein
D      E5139_04420 recombinase RecJ	K07097 K07097; uncharacterized protein
D      E5139_07430 phosphoribosyltransferase	K07101 K07101; uncharacterized protein
D      E5139_07495 amino acid-binding protein	K07103 K07103; uncharacterized protein
D      E5139_16790 YeeE/YedE family protein	K07112 K07112; uncharacterized protein
D      E5139_16795 YeeE/YedE family protein	K07112 K07112; uncharacterized protein
D      E5139_09065 SDR family oxidoreductase	K07124 K07124; uncharacterized protein
D      E5139_07845 radical SAM protein	K07129 K07129; uncharacterized protein
D      E5139_04970 MOSC domain-containing protein	K07140 K07140; MOSC domain-containing protein
D      E5139_06845 DUF418 domain-containing protein	K07148 K07148; uncharacterized protein
D      E5139_06825 twitching motility protein PilT	K07158 K07158; uncharacterized protein
D      E5139_01690 proteasome assembly chaperone family protein	K07159 K07159; uncharacterized protein
D      E5139_07225 hypothetical protein	K07163 K07163; uncharacterized protein
D      E5139_03340 bifunctional nuclease family protein	K08999 K08999; uncharacterized protein
D      E5139_03455 DUF192 domain-containing protein	K09005 K09005; uncharacterized protein
D      E5139_05360 DUF192 domain-containing protein	K09005 K09005; uncharacterized protein
D      E5139_09090 DUF99 family protein	K09120 K09120; uncharacterized protein
D      E5139_02210 hypothetical protein	K09122 K09122; uncharacterized protein
D      E5139_09380 DUF424 domain-containing protein	K09148 K09148; uncharacterized protein
D      E5139_06710 DUF460 domain-containing protein	K09150 K09150; uncharacterized protein
D      E5139_06245 DUF552 domain-containing protein	K09152 K09152; uncharacterized protein
D      E5139_00190 DUF447 family protein	K09154 K09154; uncharacterized protein
D      E5139_00110 HD domain-containing protein	K09163 K09163; uncharacterized protein
D      E5139_06640 DUF1684 domain-containing protein	K09164 K09164; uncharacterized protein
D      E5139_00815 DUF2071 domain-containing protein	K09166 K09166; uncharacterized protein
D      E5139_00820 DUF2071 domain-containing protein	K09166 K09166; uncharacterized protein
D      E5139_13715 hypothetical protein	K09167 K09167; uncharacterized protein
D      E5139_13775 YqcI/YcgG family protein	K09190 K09190; uncharacterized protein
D      E5139_04815 hypothetical protein	K09713 K09713; uncharacterized protein
D      E5139_13245 DUF354 domain-containing protein	K09726 K09726; uncharacterized protein
D      E5139_15195 DUF357 domain-containing protein	K09728 K09728; uncharacterized protein
D      E5139_14275 UPF0179 family protein	K09730 K09730; uncharacterized protein
D      E5139_01010 DUF555 domain-containing protein	K09731 K09731; uncharacterized protein
D      E5139_15170 DUF555 domain-containing protein	K09731 K09731; uncharacterized protein
D      E5139_09490 coaE operon protein	K09736 K09736; uncharacterized protein
D      E5139_02630 DUF371 domain-containing protein	K09738 K09738; uncharacterized protein
D      E5139_07230 DUF2073 domain-containing protein	K09743 K09743; uncharacterized protein
D      E5139_01485 DUF790 family protein	K09744 K09744; uncharacterized protein
D      E5139_15225 hypothetical protein	K09746 K09746; uncharacterized protein
D      E5139_08300 DNA-binding protein	K09746 K09746; uncharacterized protein
D      E5139_14265 DUF309 domain-containing protein	K09763 K09763; uncharacterized protein
D      E5139_14305 YeaH/YhbH family protein	K09786 K09786; uncharacterized protein
D      E5139_14020 Trm112 family protein	K09791 K09791; uncharacterized protein
D      E5139_16735 sulfite exporter TauE/SafE family protein	K09792 K09792; uncharacterized protein
D      E5139_00370 DUF456 domain-containing protein	K09793 K09793; uncharacterized protein
D      E5139_01795 DUF541 domain-containing protein	K09807 K09807; uncharacterized protein
D      E5139_06255 DUF541 domain-containing protein	K09807 K09807; uncharacterized protein
D      E5139_07820 DUF2309 domain-containing protein	K09822 K09822; uncharacterized protein
D      E5139_07635 DUF2237 domain-containing protein	K09966 K09966; uncharacterized protein
D      E5139_08165 exonuclease	K07502 yprB; uncharacterized protein
!
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#Last updated: September 21, 2024