+F Repair protein KO
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DNA Repair and Recombination Proteins - Halomonas sp. 'Soap Lake #7'
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D B2G49_19810 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E B2G49_08190 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E B2G49_21245 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E B2G49_06685 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D B2G49_05365 thiamin phosphate synthase superfamily K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B2G49_14030 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D B2G49_09000 6-O-methylguanine DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D B2G49_19810 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D B2G49_11165 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E B2G49_08190 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E B2G49_18710 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E B2G49_21245 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E B2G49_15045 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E B2G49_14005 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E B2G49_06685 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E B2G49_05605 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E B2G49_18770 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E B2G49_06165 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E B2G49_01885 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E B2G49_14135 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E B2G49_19345 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E B2G49_12775 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E B2G49_21565 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E B2G49_19740 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E B2G49_07045 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E B2G49_10295 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E B2G49_05525 DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B2G49_18515 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B2G49_21565 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E B2G49_19345 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E B2G49_12775 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F B2G49_19955 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F B2G49_19960 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F B2G49_20115 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F B2G49_18675 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F B2G49_08720 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E B2G49_12910 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E B2G49_04935 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E B2G49_14215 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E B2G49_00755 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E B2G49_17655 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E B2G49_13865 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E B2G49_19060 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E B2G49_13685 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E B2G49_08660 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E B2G49_05505 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E B2G49_00225 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E B2G49_06645 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E B2G49_07600 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E B2G49_12350 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E B2G49_10270 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E B2G49_19345 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E B2G49_12775 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E B2G49_05525 DNA helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B2G49_18515 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E B2G49_19750 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E B2G49_12190 restriction endonuclease subunit M K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E B2G49_11450 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E B2G49_11440 exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E B2G49_11455 exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E B2G49_12900 recombinase RecA K03553 recA; recombination protein RecA
E B2G49_07105 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E B2G49_07110 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E B2G49_07100 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E B2G49_21850 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E B2G49_14215 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E B2G49_02420 chromosome segregation protein SMC K03546 sbcC; DNA repair protein SbcC/Rad50
E B2G49_14235 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E B2G49_02415 exonuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E B2G49_12900 recombinase RecA K03553 recA; recombination protein RecA
E B2G49_21190 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E B2G49_19065 DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E B2G49_06330 AAA family ATPase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E B2G49_18635 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E B2G49_14135 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E B2G49_05675 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E B2G49_10260 recombination protein RecR K06187 recR; recombination protein RecR
E B2G49_20815 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E B2G49_06755 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E B2G49_07105 Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E B2G49_07110 Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E B2G49_07100 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E B2G49_20255 subtype I-C CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
E B2G49_21890 ATP-dependent helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E B2G49_02420 chromosome segregation protein SMC K03546 sbcC; DNA repair protein SbcC/Rad50
E B2G49_14235 hypothetical protein K03546 sbcC; DNA repair protein SbcC/Rad50
E B2G49_02415 exonuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F B2G49_06765 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F B2G49_19070 DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F B2G49_08750 DNA topoisomerase I subunit omega K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F B2G49_18590 DNA-binding protein HU K05787 hupA; DNA-binding protein HU-alpha
F B2G49_07775 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F B2G49_14135 DHH family phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F B2G49_05675 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F B2G49_10260 recombination protein RecR K06187 recR; recombination protein RecR
F B2G49_19345 DNA ligase B K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F B2G49_12775 ligA; DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F B2G49_06570 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F B2G49_07815 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F B2G49_10335 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F B2G49_14215 exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F B2G49_13535 recombinase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F B2G49_14705 DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F B2G49_19740 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F B2G49_07045 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D B2G49_13045 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D B2G49_03690 DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D B2G49_07485 DNA polymerase V subunit UmuC K03502 umuC; DNA polymerase V
D B2G49_21365 hypothetical protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D B2G49_03695 SOS mutagenesis protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D B2G49_07490 peptidase S24 K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D B2G49_12900 recombinase RecA K03553 recA; recombination protein RecA
D B2G49_08145 repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D B2G49_20815 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D B2G49_19750 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D B2G49_12895 recombinase RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D B2G49_18785 DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D B2G49_05620 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D B2G49_05365 thiamin phosphate synthase superfamily K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D B2G49_14030 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D B2G49_19725 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D B2G49_05560 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D B2G49_05565 class 1b ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024