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Transfer RNA Biogenesis - Hyperthermus butylicus
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
D Hbut_1308 ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Hbut_0556 RNase P, Rpp14 family K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Hbut_0555 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Hbut_1593 conserved archaeal protein K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D Hbut_0661 Metal-dependent hydrolase of beta lactamase, ElaC K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D Hbut_0518 universally conserved protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D Hbut_0516 uncharacterized conserved protein K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
D Hbut_1581 elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hbut_0779 Bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Hbut_1425 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Hbut_1241 Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Hbut_1110 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Hbut_1178 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
C Other AARSs
D Hbut_1607 Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hbut_0050 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Hbut_0966 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Hbut_1249 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Hbut_1188 Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Hbut_0879 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Hbut_0954 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Hbut_0887 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Hbut_0888 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Hbut_0889 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Hbut_0947 Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D Hbut_0781 universally conserved protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Hbut_1214 predicted metal-dependent hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D Hbut_0648 Metal-dependent hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D Hbut_1092 conserved archaeal protein K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
C Methyltransferases
D Hbut_0460 N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D Hbut_0720 Methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Hbut_0088 methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Hbut_1352 tRNA methyltransferase K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Hbut_0736 universally conserved protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Hbut_1116 conserved archaeal protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D Hbut_0026 conserved archaeal protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D Hbut_1144 conserved archaeal protein K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
C Psudouridine synthases
D Hbut_1329 predicted pseudouridine synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Hbut_0628 putative tRNA pseudouridine synthase D, TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D Hbut_1661 predicted pseudouridylate synthase K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
C Thiolation factors
C KEOPS/EKC complex
D Hbut_0433 predicted serine/threonine kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Hbut_0434 Metal-dependent protease, possible chaperone activity, QR17 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D Hbut_0770 universally conserved protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Hbut_0427 RNA binding protein, THUMP domain K06963 TAN1; tRNA acetyltransferase TAN1
D Hbut_1190 hypothetical protein K06963 TAN1; tRNA acetyltransferase TAN1
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D Hbut_1548 universally conserved protein K09006 K09006; RNA-free ribonuclease P [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D Hbut_0661 Metal-dependent hydrolase of beta lactamase, ElaC K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D Hbut_0014 tRNA nucleotidyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
B tRNA spricing factors
C tRNA splicing endonucleases
D Hbut_0045 General archaeal splicing enzyme K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D Hbut_0955 hypothetical protein K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
C tRNA splicing ligases
D Hbut_0518 universally conserved protein K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D Hbut_0388 2'-5' RNA ligase, Lig T K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D Hbut_1373 RNA:NAD 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Hbut_1241 Leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Hbut_0055 Lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Hbut_0779 Bifunctional aminoacyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D Hbut_0889 Tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Hbut_0947 Tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Hbut_0966 Threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Hbut_1425 Isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Hbut_1607 Alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hbut_0879 Valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Hbut_1110 Methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Hbut_1249 Seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Hbut_1188 Cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Hbut_0542 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hbut_1178 Arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Hbut_0887 Phenylalanyl-tRNA synthetase alpha chain K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Hbut_0888 Phenylalanyl-tRNA synthetase beta chain K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Hbut_0954 Histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Hbut_0034 Aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
C Trans-editing factors
D Hbut_0781 universally conserved protein K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Hbut_1214 predicted metal-dependent hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D Hbut_0648 Metal-dependent hydrolase K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferases
C Methyltransferases
D Hbut_1655 rRNA methylase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D Hbut_0870 hypothetical protein K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D Hbut_0736 universally conserved protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D Hbut_0777 hypothetical protein K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D Hbut_1559 predicted tRNA and rRNA cytosine-C5-methylase K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D Hbut_0079 conserved archaeal protein K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]
D Hbut_1654 conserved archaeal protein K16318 trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256]
D Hbut_0330 predicted DNA modification methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D Hbut_1137 conserved archaeal protein K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
C Psudouridine synthases
D Hbut_1329 predicted pseudouridine synthase K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Hbut_0628 putative tRNA pseudouridine synthase D, TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
C Thiolation factors
D Hbut_0094 predicted ATPase of the PP-loop superfamily K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
D Hbut_0591 predicted ATPase of the PP-loop superfamily K21947 ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]
C KEOPS/EKC complex
D Hbut_0433 predicted serine/threonine kinase K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D Hbut_0434 Metal-dependent protease, possible chaperone activity, QR17 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
C Other tRNA modification factors
D Hbut_1045 predicted PP-loop superfamily ATPase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Hbut_0178 6-pyruvoyl-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Hbut_0179 Organic radical activating enzyme, NrdG K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Hbut_0469 Queuine/archaeosine tRNA-ribosyltransferase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D Hbut_0566 probable thiamine biosynthesis protein, ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Hbut_0008 nucleic acid binding protein with Zn ribbon domain - conserved archaeal protein K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D Hbut_0953 predicted P-loop ATPase fused to an acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D Hbut_0612 predicted P-loop ATPase fused to an acetyltransferase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D Hbut_1153 P-loop ATPase K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D Hbut_0770 universally conserved protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
B tRNA degradation factors
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: February 29, 2024