+F Repair protein KO
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DNA Repair and Recombination Proteins - Halomonas chromatireducens
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LOKO_01531 ogt_2; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LOKO_03272 ogt_3; Methylated-DNA--protein-cysteine methyltransferase, constitutive K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LOKO_00156 phrB; Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LOKO_02053 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LOKO_00562 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LOKO_00807 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E LOKO_02385 bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D LOKO_01288 nudG; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOKO_02110 Bifunctional NMN adenylyltransferase/Nudix hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOKO_03008 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D LOKO_01531 ogt_2; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LOKO_03272 ogt_3; Methylated-DNA--protein-cysteine methyltransferase, constitutive K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D LOKO_01513 ada; Bifunctional transcriptional activator/DNA repair enzyme Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D LOKO_00156 phrB; Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E LOKO_02053 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E LOKO_01530 alkA; DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E LOKO_00562 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E LOKO_03302 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E LOKO_03003 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E LOKO_01594 nei; Endonuclease 8 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E LOKO_00807 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E LOKO_02268 exoA; Exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LOKO_02090 xthA; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E LOKO_01522 nfo; Endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E LOKO_02408 nfi; Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E LOKO_03309 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E LOKO_02447 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E LOKO_00572 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E LOKO_00143 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E LOKO_01867 uvrB_2; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E LOKO_00926 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E LOKO_00958 DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOKO_02292 uvrD_2; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOKO_02150 uvrD_1; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOKO_00572 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E LOKO_02447 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F LOKO_00110 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F LOKO_00111 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F LOKO_00141 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F LOKO_02275 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F LOKO_00929 mfd_1; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E LOKO_02920 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E LOKO_00838 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E LOKO_03290 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E LOKO_02852 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E LOKO_00962 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E LOKO_02966 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E LOKO_01085 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E LOKO_03061 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E LOKO_00945 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E LOKO_02468 polC_2; DNA polymerase III PolC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LOKO_00666 polC_1; DNA polymerase III PolC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LOKO_02123 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LOKO_01484 recD_2; RecBCD enzyme subunit RecD K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E LOKO_02609 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E LOKO_02447 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E LOKO_00958 DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOKO_02292 uvrD_2; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOKO_02150 uvrD_1; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E LOKO_00145 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E LOKO_01483 recB_2; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E LOKO_00371 recB_1; RecBCD enzyme subunit RecB K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E LOKO_01482 recC_2; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E LOKO_00372 recC_1; RecBCD enzyme subunit RecC K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E LOKO_00370 recD_1; RecBCD enzyme subunit RecD K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E LOKO_00690 recombinase A K03553 recA; recombination protein RecA
E LOKO_01852 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LOKO_01853 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LOKO_01851 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E LOKO_02939 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E LOKO_03290 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E LOKO_02410 sbcC; Nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E LOKO_02409 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E LOKO_00690 recombinase A K03553 recA; recombination protein RecA
E LOKO_00549 hypothetical protein K04485 radA; DNA repair protein RadA/Sms
E LOKO_01084 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E LOKO_02281 recG_2; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E LOKO_03309 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E LOKO_02077 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E LOKO_02607 recR; Recombination protein RecR K06187 recR; recombination protein RecR
E LOKO_03442 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E LOKO_01621 rdgC; Recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E LOKO_01852 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E LOKO_01853 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E LOKO_01851 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E LOKO_00606 type I restriction enzyme EcoKI subunit R K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E LOKO_02410 sbcC; Nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E LOKO_02409 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E LOKO_00653 ykoV_1; putative DNA repair protein YkoV K10979 ku; DNA end-binding protein Ku
E LOKO_00654 ykoV_2; putative DNA repair protein YkoV K10979 ku; DNA end-binding protein Ku
E LOKO_00656 Putative DNA ligase-like protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F LOKO_01619 gyrA_2; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F LOKO_01083 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F LOKO_01268 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F LOKO_02283 hup; DNA-binding protein HU K05787 hupA; DNA-binding protein HU-alpha
F LOKO_01402 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F LOKO_03309 recJ; Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F LOKO_02077 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F LOKO_02607 recR; Recombination protein RecR K06187 recR; recombination protein RecR
F LOKO_02447 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F LOKO_01216 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F LOKO_00431 ihfA; Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F LOKO_00917 ihfB; Integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F LOKO_03290 sbcB; Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F LOKO_00074 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F LOKO_00143 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F LOKO_01867 uvrB_2; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
F LOKO_02043 DNA binding protein, nucleoid-associated K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D LOKO_02039 dinB_2; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D LOKO_00813 dinB_1; DNA polymerase IV K03502 umuC; DNA polymerase V
D LOKO_02487 dinB_3; DNA polymerase IV K03502 umuC; DNA polymerase V
D LOKO_00812 lexA_1; LexA repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D LOKO_02486 lexA_3; LexA repressor K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D LOKO_00690 recombinase A K03553 recA; recombination protein RecA
D LOKO_02038 lexA_2; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D LOKO_02871 lexA_4; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D LOKO_03442 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D LOKO_01441 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D LOKO_00145 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D LOKO_00689 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D LOKO_00415 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D LOKO_02087 dinG; putative ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D LOKO_01288 nudG; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOKO_02110 Bifunctional NMN adenylyltransferase/Nudix hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D LOKO_03008 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D LOKO_01687 nrdZ; Ribonucleoside-diphosphate reductase NrdZ K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LOKO_03343 nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D LOKO_03344 nrdB; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024