+D GENES KO
#
KEGG Orthology (KO) - Candidatus Hydrogenisulfobacillus filiaventi
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:hfv00010]
D R50_1124 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D R50_1123 tal; Transaldolase K13810 tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
D R50_0617 glpX; fructose 1,6-bisphosphatase class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D R50_1401 fba; Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D R50_1599 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D R50_2222 tpiA; triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D R50_2224 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D R50_2223 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D R50_2221 pgm; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D R50_2474 gpmI; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D R50_2220 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D R50_0996 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D R50_2116 ppdK; Pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D R50_0058 pps; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D R50_2473 pdhA; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D R50_2472 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D R50_2471 putative Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_0484 2-oxoglutarate oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D R50_0483 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D R50_0411 adhA; putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
C 00020 Citrate cycle (TCA cycle) [PATH:hfv00020]
D R50_0370 mmgD; bifunctional citrate synthase/2-methylcitrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D R50_1331 citA; citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1]
D R50_1285 citB; aconitate hydratase (bifunctional aconitase) K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D R50_0847 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D R50_0566 odhA; 2-oxoglutarate dehydrogenase, E1 subunit K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D R50_0567 odhB; 2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit) K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_0484 2-oxoglutarate oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D R50_0483 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D R50_0851 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D R50_0850 sucC; Succinate--CoA ligase [ADP-forming] subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D R50_1456 sdhA; Succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D R50_1457 sdhB; Succinate dehydrogenase, iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D R50_1459 sdhC; Succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D R50_1458 conserved membrane protein of unknown function K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D R50_0666 fumC; Fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D R50_0667 putative Fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D R50_2473 pdhA; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D R50_2472 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D R50_2471 putative Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:hfv00030]
D R50_1123 tal; Transaldolase K13810 tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
D R50_0450 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D R50_1121 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D R50_1119 pgl; Putative 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]
D R50_1122 yqeC; Putative 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D R50_1689 rpe; ribulose-5-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D R50_1691 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D R50_1692 tal; Transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D R50_0628 rpiB; D-ribose 5-phosphate epimerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D R50_2470 putative phosphoketolase K01621 xfp; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]
D R50_2541 deoC; Deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D R50_0659 rbsK; Ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15]
D R50_1166 deoB; 1,5-phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_2625 prs; phosphoribosylpyrophosphate synthetase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D R50_1128 putative Gluconokinase K25031 gntK; gluconokinase [EC:2.7.1.12]
D R50_1401 fba; Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D R50_1599 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D R50_0617 glpX; fructose 1,6-bisphosphatase class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
C 00040 Pentose and glucuronate interconversions [PATH:hfv00040]
D R50_0333 tuaD; UDP-glucose 6-dehydrogenase TuaD K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D R50_2593 yngB; putative UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D R50_1689 rpe; ribulose-5-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D R50_0086 putative Xylulokinase K00854 xylB; xylulokinase [EC:2.7.1.17]
D R50_0561 putative D-ribulose kinase K22935 XK1; D-ribulokinase [EC:2.7.1.47]
D R50_2767 Class II aldolase family protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:hfv00051]
D R50_1330 PfkB domain-containing protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_2594 Mannose-1-phosphate guanylyltransferase (GDP) K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D R50_0160 putative Mannose-1-phosphate guanylyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D R50_2767 Class II aldolase family protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D R50_0617 glpX; fructose 1,6-bisphosphatase class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D R50_1401 fba; Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D R50_1599 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D R50_2222 tpiA; triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D R50_0628 rpiB; D-ribose 5-phosphate epimerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D R50_0040 putative PTS sugar transporter subunit IIA K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
C 00052 Galactose metabolism [PATH:hfv00052]
D R50_0336 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D R50_0832 exoB; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D R50_2315 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D R50_2593 yngB; putative UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_1124 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D R50_0197 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9]
C 00053 Ascorbate and aldarate metabolism
D R50_0333 tuaD; UDP-glucose 6-dehydrogenase TuaD K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
C 00500 Starch and sucrose metabolism [PATH:hfv00500]
D R50_2593 yngB; putative UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D R50_0408 putative Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21]
D R50_2682 bglB; Thermostable beta-glucosidase B K05350 bglB; beta-glucosidase [EC:3.2.1.21]
D R50_0128 Glyco_hydro_57 domain-containing protein K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1]
D R50_1814 nplT; Neopullulanase K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]
D R50_0451 Glucan 1,4-alpha-glucosidase K01178 SGA1; glucoamylase [EC:3.2.1.3]
D R50_1566 otsA; Trehalose-6-phosphate synthase K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347]
D R50_1567 Trehalose-6-phosphate phosphatase K01087 otsB; trehalose 6-phosphate phosphatase [EC:3.1.3.12]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_1124 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D R50_1123 tal; Transaldolase K13810 tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
D R50_1330 PfkB domain-containing protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00620 Pyruvate metabolism [PATH:hfv00620]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_0484 2-oxoglutarate oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D R50_0483 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D R50_2473 pdhA; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D R50_2472 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D R50_2471 putative Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_0411 adhA; putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D R50_2476 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D R50_2475 ptb; phosphate BCFA and butyryl coenzyme A transferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D R50_0996 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D R50_1141 accC; acetyl-CoA carboxylase subunit (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D R50_1804 putative Acylphosphate phosphohydrolase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D R50_0122 putative D-lactate dehydrogenase (cytochrome) K00102 LDHD; D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4]
D R50_0849 maeB; NADP-dependent malic enzyme (conversion of malate into pyruvate, anabolic) K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D R50_0666 fumC; Fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D R50_0667 putative Fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D R50_1538 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D R50_2116 ppdK; Pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D R50_0058 pps; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D R50_0812 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D R50_2652 cimA; (R)-citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D R50_0465 nifV; Homocitrate synthase K02594 nifV; homocitrate synthase NifV [EC:2.3.3.14]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:hfv00630]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D R50_0370 mmgD; bifunctional citrate synthase/2-methylcitrate synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D R50_1331 citA; citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1]
D R50_1285 citB; aconitate hydratase (bifunctional aconitase) K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_0121 Glycolate dehydrogenase, iron-sulfur subunit GlcF K11473 glcF; glycolate dehydrogenase iron-sulfur subunit [EC:1.1.99.14]
D R50_0264 putative Ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D R50_1596 cbbL; Ribulose bisphosphate carboxylase large chain K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D R50_1688 cbbL; Ribulose bisphosphate carboxylase large chain K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D R50_1595 cbbS; Ribulose bisphosphate carboxylase small chain K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D R50_1687 cbbS; Ribulose bisphosphate carboxylase small chain K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D R50_1125 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2306 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_1415 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D R50_1419 gcvT; aminomethyltransferase (glycine cleavage system protein T) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_0686 putative Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_0694 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1174 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1418 gcvH; glycine cleavage complex lipoylprotein K02437 gcvH; glycine cleavage system H protein
D R50_2343 gcvH; Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_2713 Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D R50_1117 purU; formyltetrahydrofolate hydrolase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D R50_1821 fmdA; Formamidase K01455 fmdA; formamidase [EC:3.5.1.49]
C 00640 Propanoate metabolism [PATH:hfv00640]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2476 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D R50_2475 ptb; phosphate BCFA and butyryl coenzyme A transferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D R50_2758 bkdAA; branched-chain alpha-keto acid dehydrogenase E1 subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D R50_2759 bkdAA; branched-chain alpha-keto acid dehydrogenase E1 subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D R50_2757 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D R50_2756 bkdB; branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase) K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_1141 accC; acetyl-CoA carboxylase subunit (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_0850 sucC; Succinate--CoA ligase [ADP-forming] subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D R50_0851 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D R50_0369 mmgE; 2-methylcitrate dehydratase (promiscuous) K01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]
D R50_1285 citB; aconitate hydratase (bifunctional aconitase) K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D R50_0368 mmgF; 2-methylisocitrate lyase K03417 prpB; methylisocitrate lyase [EC:4.1.3.30]
C 00650 Butanoate metabolism [PATH:hfv00650]
D R50_0922 gcdC; Glutaconyl-CoA decarboxylase subunit gamma K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D R50_1456 sdhA; Succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D R50_1457 sdhB; Succinate dehydrogenase, iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D R50_1459 sdhC; Succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D R50_1458 conserved membrane protein of unknown function K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_0059 gabD; putative succinate-semialdehyde dehydrogenase [NADP(+)] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D R50_0484 2-oxoglutarate oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D R50_0483 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D R50_0814 ilvB; acetohydroxy-acid synthase (large subunit) K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:hfv00660]
D R50_0814 ilvB; acetohydroxy-acid synthase (large subunit) K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D R50_0850 sucC; Succinate--CoA ligase [ADP-forming] subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D R50_0851 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D R50_1801 leuC; 3-isopropylmalate dehydratase (large subunit) K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D R50_1800 leuD; 3-isopropylmalate dehydratase (small subunit) K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D R50_0813 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:hfv00562]
D R50_0568 Phosphoesterase K01114 plc; phospholipase C [EC:3.1.4.3]
D R50_2222 tpiA; triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00566 Sulfoquinovose metabolism [PATH:hfv00566]
D R50_0584 agl; UDP-sulfoquinovose synthase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D R50_2388 mgtA; GDP-mannose-dependent alpha-mannosyltransferase K06119 SQD2; sulfoquinovosyltransferase [EC:2.4.1.-]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:hfv00190]
D R50_1842 nuoA; NADH:quinone oxidoreductase subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D R50_1841 nuoB; NADH:quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D R50_2353 nuoB; NADH:quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D R50_1840 nuoC; NADH:quinone oxidoreductase subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D R50_1839 nuoD; NADH:quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D R50_2355 nuoD; NADH:quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D R50_1838 NuoE; NADH:quinone oxidoreductase subunit E K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D R50_1551 putative NADH-quinone oxidoreductase subunit F 2 K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D R50_1837 nuoF; NADH:ubiquinone oxidoreductase subunit F K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D R50_1910 NADH dehydrogenase K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D R50_1836 putative NADH-quinone oxidoreductase subunit G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D R50_1835 nuoH; NADH:ubiquinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D R50_2356 nuoH; NADH:ubiquinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D R50_1834 nuoI; NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D R50_2357 nuoI; NADH:quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D R50_1833 nuoJ; NADH-quinone oxidoreductase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D R50_2358 nuoJ; NADH:quinone oxidoreductase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D R50_1832 nuoK; NADH:ubiquinone oxidoreductase subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D R50_2362 protein of unknown function K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D R50_1831 nuoL; NADH-quinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D R50_2359 nuoL; NADH:ubiquinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D R50_1830 NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D R50_1829 nuoN; NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D R50_2361 NADH-ubiquinone oxidoreductase chain N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D R50_2352 nuoA; NADH:quinone oxidoreductase subunit A K05574 ndhC; NAD(P)H-quinone oxidoreductase subunit 3 [EC:7.1.1.2]
D R50_2360 nuoM; NADH:quinone oxidoreductase subunit M K05575 ndhD; NAD(P)H-quinone oxidoreductase subunit 4 [EC:7.1.1.2]
D R50_1456 sdhA; Succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D R50_1457 sdhB; Succinate dehydrogenase, iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D R50_1459 sdhC; Succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D R50_1458 conserved membrane protein of unknown function K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D R50_1001 Rieske domain-containing protein K03886 qcrA; quinol---cytochrome c reductase iron-sulfur subunit, bacillus type [EC:7.1.1.8]
D R50_1002 qcrB; menaquinol:cytochrome c oxidoreductase (cytochrome b subunit) K03887 qcrB; quinol---cytochrome c reductase cytochrome b subunit, bacillus type [EC:7.1.1.8]
D R50_1003 Cytochrome c domain-containing protein K03888 qcrC; quinol---cytochrome c reductase cytochrome c subunit, bacillus type [EC:7.1.1.8]
D R50_1635 ctaB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D R50_0035 Cytochrome C oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D R50_1638 ctaD; Cytochrome C oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D R50_1639 ctaC; Cytochrome C oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D R50_1633 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA K02259 COX15; heme a synthase [EC:1.17.99.9]
D R50_0764 conserved membrane protein of unknown function K02829 qoxD; cytochrome aa3-600 menaquinol oxidase subunit IV [EC:7.1.1.5]
D R50_0765 qoxC; cytochrome aa3-600 quinol oxidase (subunit III) K02828 qoxC; cytochrome aa3-600 menaquinol oxidase subunit III [EC:7.1.1.5]
D R50_0766 qoxB; cytochrome aa3-600 quinol oxidase (subunit I) K02827 qoxB; cytochrome aa3-600 menaquinol oxidase subunit I [EC:7.1.1.5]
D R50_0767 qoxA; Quinol oxidase subunit 2 K02826 qoxA; cytochrome aa3-600 menaquinol oxidase subunit II [EC:7.1.1.5]
D R50_0789 cydA; cytochrome bb' ubiquinol oxidase (subunit I) K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_0890 cydA; cytochrome bb' ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_0944 cydA; cytochrome bb' ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_1315 cydA; cytochrome bb' ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_0891 cydB; cytochrome bb' ubiquinol oxidase (subunit II) K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_0945 cydB; cytochrome bb' ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_1033 membrane protein of unknown function K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_1316 cydB; cytochrome bb' ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_0636 atpA; ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D R50_0638 atpD; ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D R50_0637 atpG; ATP synthase subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D R50_0635 atpH; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D R50_0639 atpC; ATP synthase subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D R50_0632 atpB; ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D R50_0634 atpF; ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D R50_0633 atpE; ATP synthase subunit c K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D R50_1484 yloB; Calcium-transporting ATPase K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1]
D R50_2536 Pirin K01535 PMA1; H+-transporting ATPase [EC:7.1.2.1]
D R50_1287 ppa; Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D R50_2297 Inorganic pyrophospatase PpaX K06019 ppaX; pyrophosphatase PpaX [EC:3.6.1.1]
D R50_2582 conserved membrane protein of unknown function
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:hfv00710]
D R50_0264 putative Ribulose-bisphosphate carboxylase K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D R50_1596 cbbL; Ribulose bisphosphate carboxylase large chain K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D R50_1688 cbbL; Ribulose bisphosphate carboxylase large chain K01601 rbcL; ribulose-bisphosphate carboxylase large chain [EC:4.1.1.39]
D R50_1595 cbbS; Ribulose bisphosphate carboxylase small chain K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D R50_1687 cbbS; Ribulose bisphosphate carboxylase small chain K01602 rbcS; ribulose-bisphosphate carboxylase small chain [EC:4.1.1.39]
D R50_2223 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D R50_2224 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D R50_1401 fba; Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D R50_1599 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D R50_0617 glpX; fructose 1,6-bisphosphatase class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D R50_1691 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D R50_0628 rpiB; D-ribose 5-phosphate epimerase K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D R50_1690 prk; Phosphoribulokinase K00855 PRK; phosphoribulokinase [EC:2.7.1.19]
D R50_2222 tpiA; triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D R50_1689 rpe; ribulose-5-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D R50_1692 tal; Transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D R50_1123 tal; Transaldolase K13810 tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
D R50_1538 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D R50_2116 ppdK; Pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:hfv00720]
D R50_0058 pps; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D R50_2116 ppdK; Pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D R50_1538 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D R50_0666 fumC; Fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D R50_0667 putative Fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D R50_1456 sdhA; Succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D R50_1457 sdhB; Succinate dehydrogenase, iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D R50_1459 sdhC; Succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D R50_1458 conserved membrane protein of unknown function K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D R50_0851 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D R50_0850 sucC; Succinate--CoA ligase [ADP-forming] subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D R50_0484 2-oxoglutarate oxidoreductase, alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D R50_0483 2-oxoacid:ferredoxin oxidoreductase 1, subunit beta K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D R50_0847 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D R50_1285 citB; aconitate hydratase (bifunctional aconitase) K27802 acnA; aconitate hydratase A / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]
D R50_1141 accC; acetyl-CoA carboxylase subunit (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D R50_1145 folD; methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D R50_0939 cooS; Putative carbon monoxide dehydrogenase small subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D R50_2475 ptb; phosphate BCFA and butyryl coenzyme A transferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D R50_2476 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:hfv00680]
D R50_1893 fdhA; Glutathione-independent formaldehyde dehydrogenase K00148 fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46]
D R50_0939 cooS; Putative carbon monoxide dehydrogenase small subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
D R50_1415 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D R50_2220 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D R50_1538 Phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D R50_1401 fba; Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D R50_1599 fba; Fructose-bisphosphate aldolase K01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]
D R50_0617 glpX; fructose 1,6-bisphosphatase class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D R50_2476 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D R50_2475 ptb; phosphate BCFA and butyryl coenzyme A transferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_0058 pps; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D R50_2221 pgm; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D R50_2474 gpmI; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D R50_0472 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D R50_1629 xecG; Phosphosulfolactate synthase K08097 comA; phosphosulfolactate synthase [EC:4.4.1.19]
D R50_1628 comB; putative 2-phosphosulfolactate phosphatase K05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71]
C 00910 Nitrogen metabolism [PATH:hfv00910]
D R50_1821 fmdA; Formamidase K01455 fmdA; formamidase [EC:3.5.1.49]
D R50_1493 Major facilitator superfamily MFS_1 K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D R50_1496 Nitrate/nitrite transporter K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D R50_1501 narG; nitrate reductase (alpha subunit) K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D R50_1500 narH; nitrate reductase (beta subunit) K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D R50_1498 narI; nitrate reductase (gamma subunit) K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-]
D R50_1317 nirK; Nitrite reductase (NO-forming) K00368 nirK; nitrite reductase (NO-forming) [EC:1.7.2.1]
D R50_0576 norB; Nitric oxide reductase K04561 norB; nitric oxide reductase subunit B [EC:1.7.2.5]
D R50_0458 nifD; Nitrogenase molybdenum-iron protein alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D R50_0457 nifK; Nitrogenase molybdenum-iron protein beta chain K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D R50_0459 nifH; Nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D R50_0919 gudB; Glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D R50_1125 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2306 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_0395 Glutamine amidotransferase type-2 domain-containing protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D R50_1497 Carbonic anhydrase (modular protein) K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:hfv00920]
D R50_2692 Glycine/betaine ABC transporter substrate-binding protein K15551 tauA; taurine transport system substrate-binding protein
D R50_2693 tauC; taurine transporter subunit; membrane component of ABC superfamily K15552 tauC; taurine transport system permease protein
D R50_0555 soeA; Sulfite dehydrogenase subunit A K21307 soeA; sulfite dehydrogenase (quinone) subunit SoeA [EC:1.8.5.6]
D R50_0556 soeB; Sulfite dehydrogenase subunit B K21308 soeB; sulfite dehydrogenase (quinone) subunit SoeB
D R50_0557 Anaerobic dimethyl sulfoxide reductase chain C K21309 soeC; sulfite dehydrogenase (quinone) subunit SoeC
D R50_0046 Pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D R50_0721 Pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D R50_0892 Pyr_redox_2 domain-containing protein K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D R50_1037 protein of unknown function K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D R50_2332 Sulfide-quinone oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D R50_2695 NADH dehydrogenase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D R50_0249 sor; Sulfur oxygenase/reductase K16952 sor; sulfur oxygenase/reductase [EC:1.13.11.55]
D R50_1684 sor; Sulfur oxygenase/reductase K16952 sor; sulfur oxygenase/reductase [EC:1.13.11.55]
D R50_2558 Thiosulfate dehydrogenase [quinone] small subunit K16936 doxA; thiosulfate dehydrogenase (quinone) small subunit [EC:1.8.5.2]
D R50_2559 Thiosulfate dehydrogenase [quinone] large subunit K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D R50_2562 tth; Tetrathionate hydrolase K27925 tetH; tetrathionate hydrolase [EC:3.12.1.-]
D R50_0703 Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D R50_1277 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D R50_1328 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D R50_0737 metXA; Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D R50_0413 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D R50_0742 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:hfv00061]
D R50_1141 accC; acetyl-CoA carboxylase subunit (biotin carboxylase subunit) K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D R50_1610 acpA; acyl carrier protein K02078 acpP; acyl carrier protein
D R50_1612 fabD; malonyl CoA:acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_2602 Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_1614 fabHA; beta-ketoacyl-acyl carrier protein synthase III 1 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D R50_1609 fabF; beta-ketoacyl-acyl carrier protein synthase II (involved in pimelate synthesis) K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D R50_2601 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D R50_1611 fabG; beta-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_2750 Short-chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_0866 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D R50_0443 NADH:quinone reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D R50_2604 Enoyl-(acyl-carrier-protein) reductase [NADPH] K10780 fabL; enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104]
D R50_1570 Long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:hfv00071]
D R50_1570 Long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D R50_0411 adhA; putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis [PATH:hfv00074]
D R50_1794 acpS; Holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D R50_1610 acpA; acyl carrier protein K02078 acpP; acyl carrier protein
D R50_1612 fabD; malonyl CoA:acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_2602 Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:hfv00561]
D R50_2713 Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D R50_2686 dhaK; dihydroxyacetone kinase, N-terminal domain K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121]
D R50_2687 dhaL; dihydroxyacetone kinase, C-terminal domain K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121]
D R50_1615 plsX; phosphate:acyl-ACP acyltransferase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D R50_1767 plsY; Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D R50_1211 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D R50_2123 Diacylglycerol kinase K00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D R50_0409 Diacylglycerol kinase K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D R50_0822 Galactosyldiacylglycerol synthase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
D R50_1156 Galactosyldiacylglycerol synthase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
D R50_0584 agl; UDP-sulfoquinovose synthase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D R50_2388 mgtA; GDP-mannose-dependent alpha-mannosyltransferase K06119 SQD2; sulfoquinovosyltransferase [EC:2.4.1.-]
C 00564 Glycerophospholipid metabolism [PATH:hfv00564]
D R50_1214 gpsA; Glycerol-3-phosphate dehydrogenase [NAD(P)+] 1 K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D R50_1767 plsY; Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D R50_1211 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D R50_2123 Diacylglycerol kinase K00901 dgkA; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D R50_0409 Diacylglycerol kinase K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D R50_0568 Phosphoesterase K01114 plc; phospholipase C [EC:3.1.4.3]
D R50_1254 Phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D R50_1372 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
C 00565 Ether lipid metabolism
D R50_0568 Phosphoesterase K01114 plc; phospholipase C [EC:3.1.4.3]
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:hfv00230]
D R50_1016 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D R50_1162 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D R50_1166 deoB; 1,5-phosphopentomutase K01839 deoB; phosphopentomutase [EC:5.4.2.7]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_2625 prs; phosphoribosylpyrophosphate synthetase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D R50_1756 purF; glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D R50_1752 purD; Phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D R50_1754 purN; Phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D R50_1757 purL; Phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D R50_1759 purS; Phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D R50_1758 purQ; phosphoribosylformylglycinamidine synthetase subunit I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D R50_1755 purM; phosphoribosylaminoimidazole synthetase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D R50_1605 purK; N5-carboxyaminoimidazole ribonucleotide synthase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D R50_1606 purE; N5-carboxyaminoimidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D R50_1760 purC; phosphoribosylaminoimidazole succinocarboxamide synthetase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D R50_1761 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D R50_1753 purH; fused phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D R50_1235 surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D R50_0972 Polyphenol oxidase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D R50_1764 hprT; hypoxanthine-guanine phosphoribosyltransferase K00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]
D R50_1773 guaB; inosine-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D R50_1226 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D R50_2210 rdgB; deoxyinosine/deoxyxanthosine triphosphate pyrophosphatase, promiscuous (subunit A) K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D R50_0419 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A K13481 xdhA; xanthine dehydrogenase small subunit [EC:1.17.1.4]
D R50_0420 Xanthine dehydrogenase, molybdenum binding subunit K13482 xdhB; xanthine dehydrogenase large subunit [EC:1.17.1.4]
D R50_1763 guaA; GMP synthetase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D R50_0051 putative Guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D R50_0273 nrdA; Ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D R50_0272 nrdB; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D R50_0180 Ribonucleotide reductase of class III (anaerobic), large subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D R50_2051 Ribonucleotide reductase of class III (anaerobic), large subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D R50_1864 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 dgt; dGTPase [EC:3.1.5.1]
D R50_1466 rsh; GTP pyrophosphokinase (RelA/SpoT) K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D R50_2768 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D R50_0431 ade; Adenine deaminase K01486 ade; adenine deaminase [EC:3.5.4.2]
D R50_1364 pdeB; 2'3' and 3'5' cyclic nucleotide monophosphates phosphodiesterase involved in biofilm formation K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D R50_2430 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D R50_2259 ureC; Urease (alpha subunit) K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D R50_2260 ureB; Urease (beta subunit) K01429 ureB; urease subunit beta [EC:3.5.1.5]
D R50_2261 ureA; Urease (gamma subunit) K01430 ureA; urease subunit gamma [EC:3.5.1.5]
C 00240 Pyrimidine metabolism [PATH:hfv00240]
D R50_0986 pyrAB; pyrimidine-specific carbamoyl-phosphate synthetase (large subunit) K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D R50_0985 pyrAA; pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit) K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D R50_0983 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D R50_0984 pyrC; Dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D R50_0988 pyrD; dihydroorotate dehydrogenase (catalytic subunit) K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]
D R50_0987 pyrK; Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit K02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit
D R50_0990 pyrE; Orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D R50_0989 pyrF; Orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D R50_1251 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D R50_1226 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D R50_2187 yhdE; putative septum formation protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D R50_2663 pyrG; CTP synthetase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D R50_1210 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D R50_1235 surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D R50_0629 upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D R50_0982 pyrR; transcriptional attenuator and uracil phosphoribosyltransferase activity K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D R50_1364 pdeB; 2'3' and 3'5' cyclic nucleotide monophosphates phosphodiesterase involved in biofilm formation K09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]
D R50_0660 Inosine-uridine preferring nucleoside hydrolase K01250 rihA; pyrimidine-specific ribonucleoside hydrolase [EC:3.2.2.-]
D R50_0801 pdp; Pyrimidine-nucleoside phosphorylase K00756 pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]
D R50_2538 cdd; Cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D R50_0180 Ribonucleotide reductase of class III (anaerobic), large subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D R50_2051 Ribonucleotide reductase of class III (anaerobic), large subunit K21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]
D R50_0489 dcd; dCTP deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D R50_0273 nrdA; Ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D R50_0272 nrdB; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D R50_2645 tmk; Thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D R50_0577 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D R50_2085 Thymidine kinase (modular protein) K00857 tdk; thymidine kinase [EC:2.7.1.21]
D R50_1540 thyX; Flavin-dependent thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D R50_0428 Dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D R50_0427 Acyltransferase K01431 UPB1; beta-ureidopropionase [EC:3.5.1.6]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:hfv00250]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_2597 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D R50_1391 asnO; Asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D R50_2113 Asparagine synthetase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D R50_1164 ald; L-alanine dehydrogenase (NAD-dependent) K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D R50_2300 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D R50_2299 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D R50_2768 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D R50_1761 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D R50_0983 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_0059 gabD; putative succinate-semialdehyde dehydrogenase [NADP(+)] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D R50_0395 Glutamine amidotransferase type-2 domain-containing protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D R50_0919 gudB; Glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D R50_2657 rocA; delta-1-pyrroline-5 carboxylate dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D R50_1125 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2306 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_0986 pyrAB; pyrimidine-specific carbamoyl-phosphate synthetase (large subunit) K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D R50_0985 pyrAA; pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit) K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D R50_1758 purQ; phosphoribosylformylglycinamidine synthetase subunit I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D R50_1815 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D R50_1756 purF; glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:hfv00260]
D R50_1522 dapG; aspartokinase I (alpha and beta subunits) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_2607 lysCA; aspartokinase II alpha subunit (aa 1->408) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_1523 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D R50_1136 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D R50_1353 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D R50_1415 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D R50_2713 Glycerate kinase K00865 glxK; glycerate 2-kinase [EC:2.7.1.165]
D R50_2221 pgm; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D R50_2474 gpmI; phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D R50_0472 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D R50_1419 gcvT; aminomethyltransferase (glycine cleavage system protein T) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_0686 putative Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_0694 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1174 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1418 gcvH; glycine cleavage complex lipoylprotein K02437 gcvH; glycine cleavage system H protein
D R50_2343 gcvH; Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_0413 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D R50_0742 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D R50_2628 tdcB; L-threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D R50_1662 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D R50_1663 trpB; tryptophan synthase (beta subunit) K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:hfv00270]
D R50_0703 Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D R50_1277 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D R50_1328 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D R50_0413 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D R50_0742 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D R50_2705 5,10-methylenetetrahydrofolate reductase / Homolog of homocysteine-binding domain K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
D R50_2703 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D R50_2704 metE; Methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D R50_0643 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D R50_1225 speD; S-adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D R50_0291 speE; Polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16]
D R50_2747 speE; spermidine synthase; polyamine metabolism K00797 speE; spermidine synthase [EC:2.5.1.16]
D R50_0972 Polyphenol oxidase K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D R50_0432 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D R50_1230 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D R50_1228 putative 6-oxopurine nucleoside phosphorylase K19696 mtiP; 5'-methylthioinosine phosphorylase [EC:2.4.2.44]
D R50_0215 mtnA; methylthioribose-1-phosphate isomerase (methionine salvage pathway) K08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]
D R50_0393 mtnE; Transaminase MtnE K08969 mtnE; L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase [EC:2.6.1.117]
D R50_1697 mdeA; L-methionine gamma-lyase K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11]
D R50_1918 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2019 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_1229 S-inosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D R50_1522 dapG; aspartokinase I (alpha and beta subunits) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_2607 lysCA; aspartokinase II alpha subunit (aa 1->408) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_1523 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D R50_1136 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D R50_0737 metXA; Homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D R50_2549 metY; O-acetyl-L-homoserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D R50_0816 ilvE; Putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_2305 ilvE; putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0848 mdh; Malate dehydrogenase (NAD-dependent) K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D R50_0472 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:hfv00280]
D R50_0816 ilvE; Putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_2305 ilvE; putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_1159 bcd; branched-chain amino acid dehydrogenase K00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]
D R50_2758 bkdAA; branched-chain alpha-keto acid dehydrogenase E1 subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D R50_2759 bkdAA; branched-chain alpha-keto acid dehydrogenase E1 subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D R50_2757 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D R50_2756 bkdB; branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase) K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2397 acdA; Acyl-CoA dehydrogenase K11410 acdH; short-chain 2-methylacyl-CoA dehydrogenase [EC:1.3.8.5]
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_2298 PGD; 6-phosphogluconate dehydrogenase
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:hfv00290]
D R50_2628 tdcB; L-threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D R50_1801 leuC; 3-isopropylmalate dehydratase (large subunit) K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D R50_1800 leuD; 3-isopropylmalate dehydratase (small subunit) K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D R50_0813 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D R50_0814 ilvB; acetohydroxy-acid synthase (large subunit) K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D R50_0811 ilvC; acetohydroxy-acid isomeroreductase (NADP-dependent) K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D R50_0815 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D R50_0816 ilvE; Putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_2305 ilvE; putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_1159 bcd; branched-chain amino acid dehydrogenase K00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]
D R50_0812 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D R50_2652 cimA; (R)-citramalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:hfv00300]
D R50_1136 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D R50_1522 dapG; aspartokinase I (alpha and beta subunits) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_2607 lysCA; aspartokinase II alpha subunit (aa 1->408) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_1523 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D R50_2526 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D R50_1474 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D R50_2301 argD; N-acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D R50_1022 dapF; Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D R50_2527 dapL; LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D R50_1189 lysA; meso-2,6-diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D R50_0662 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_0956 murE; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_2505 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_0957 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:hfv00310]
D R50_0567 odhB; 2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit) K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_1223 patA; Putrescine aminotransferase K09251 patA; putrescine aminotransferase [EC:2.6.1.82]
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_0059 gabD; putative succinate-semialdehyde dehydrogenase [NADP(+)] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D R50_0997 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
C 00220 Arginine biosynthesis [PATH:hfv00220]
D R50_2406 argF; Ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D R50_2300 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D R50_2299 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D R50_2409 rocF; Arginase K01476 rocF; arginase [EC:3.5.3.1]
D R50_2259 ureC; Urease (alpha subunit) K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D R50_2260 ureB; Urease (beta subunit) K01429 ureB; urease subunit beta [EC:3.5.1.5]
D R50_2261 ureA; Urease (gamma subunit) K01430 ureA; urease subunit gamma [EC:3.5.1.5]
D R50_1758 purQ; phosphoribosylformylglycinamidine synthetase subunit I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D R50_1125 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2306 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_0986 pyrAB; pyrimidine-specific carbamoyl-phosphate synthetase (large subunit) K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D R50_0985 pyrAA; pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit) K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D R50_0919 gudB; Glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0391 GCN5-related N-acetyltransferase K00619 argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
D R50_2303 argJ; ornithine acetyltransferase; amino-acid acetyltransferase K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D R50_2302 argB; Acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D R50_2304 argC; N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D R50_2301 argD; N-acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:hfv00330]
D R50_1005 conserved protein of unknown function K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D R50_2748 pdaD; Pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D R50_2262 speB; putative agmatinase 2 K01480 speB; agmatinase [EC:3.5.3.11]
D R50_2746 speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D R50_0291 speE; Polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16]
D R50_2747 speE; spermidine synthase; polyamine metabolism K00797 speE; spermidine synthase [EC:2.5.1.16]
D R50_1225 speD; S-adenosylmethionine decarboxylase K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D R50_1223 patA; Putrescine aminotransferase K09251 patA; putrescine aminotransferase [EC:2.6.1.82]
D R50_0075 putative oxidoreductase OrdL K09471 puuB; gamma-glutamylputrescine oxidase [EC:1.4.3.-]
D R50_2409 rocF; Arginase K01476 rocF; arginase [EC:3.5.3.1]
D R50_0734 proC; Pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D R50_2420 fadM; Proline dehydrogenase 1 K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D R50_2657 rocA; delta-1-pyrroline-5 carboxylate dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D R50_1542 proB; Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D R50_1541 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0997 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
C 00340 Histidine metabolism [PATH:hfv00340]
D R50_0730 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D R50_0724 hisIE; bifunctional phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase K11755 hisIE; phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
D R50_0726 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D R50_0727 hisH; Imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D R50_0725 hisF; imidazole glycerol phosphate synthase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D R50_0728 hisB; imidazoleglycerol-phosphate dehydratase [Mn(II)-dependent] K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D R50_0081 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0732 hisC; Histidinol-phosphate aminotransferase 2 K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0729 hisD; Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D R50_1799 Glutamate formimidoyltransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
C 00350 Tyrosine metabolism [PATH:hfv00350]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0081 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0732 hisC; Histidinol-phosphate aminotransferase 2 K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0411 adhA; putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D R50_0059 gabD; putative succinate-semialdehyde dehydrogenase [NADP(+)] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism [PATH:hfv00360]
D R50_2590 paaA; Phenylacetic acid degradation protein K02609 paaA; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA [EC:1.14.13.149]
D R50_2589 Phenylacetate-CoA oxygenase, PaaI subunit K02611 paaC; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaC [EC:1.14.13.149]
D R50_2588 Phenylacetate-CoA oxygenase, PaaJ subunit K02612 paaD; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0081 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0732 hisC; Histidinol-phosphate aminotransferase 2 K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0997 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
C 00380 Tryptophan metabolism
D R50_0567 odhB; 2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit) K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:hfv00400]
D R50_1659 aroF; Phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D R50_1420 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D R50_1414 yqhS; 3-dehydroquinate dehydratase, type II K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D R50_1421 aroK; Shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D R50_1657 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvoylshikimate-3-phosphate synthase) K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D R50_1422 aroF; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D R50_1668 trpE; anthranilate synthase K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D R50_1667 pabA; 4-amino-4-deoxychorismate synthase; anthranilate synthase (subunit II) K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D R50_1666 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D R50_1664 trpF; N-(5'-phosphoribosyl)anthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D R50_1665 trpC; Indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D R50_1662 trpA; Tryptophan synthase alpha chain K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D R50_1663 trpB; tryptophan synthase (beta subunit) K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D R50_1209 aroH; chorismate mutase K06208 aroH; chorismate mutase [EC:5.4.99.5]
D R50_1658 Arogenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D R50_0817 Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0081 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0732 hisC; Histidinol-phosphate aminotransferase 2 K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:hfv00410]
D R50_0492 panD; Aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_1201 panC; Pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D R50_0428 Dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D R50_0427 Acyltransferase K01431 UPB1; beta-ureidopropionase [EC:3.5.1.6]
C 00430 Taurine and hypotaurine metabolism [PATH:hfv00430]
D R50_1164 ald; L-alanine dehydrogenase (NAD-dependent) K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D R50_0919 gudB; Glutamate dehydrogenase K00260 gudB; glutamate dehydrogenase [EC:1.4.1.2]
D R50_2475 ptb; phosphate BCFA and butyryl coenzyme A transferase K00625 pta; phosphate acetyltransferase [EC:2.3.1.8]
D R50_2476 ackA; Acetate kinase K00925 ackA; acetate kinase [EC:2.7.2.1]
D R50_0893 protein of unknown function
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:hfv00450]
D R50_2705 5,10-methylenetetrahydrofolate reductase / Homolog of homocysteine-binding domain K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
D R50_2703 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D R50_2704 metE; Methionine synthase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D R50_1697 mdeA; L-methionine gamma-lyase K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11]
D R50_1429 sufS; cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D R50_1471 trxB; Thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D R50_2735 Pyr_redox_2 domain-containing protein K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D R50_0656 selD; Selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D R50_0858 selA; L-seryl-tRNA(Sec) selenium transferase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D R50_2638 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:hfv00460]
D R50_0408 putative Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21]
D R50_2682 bglB; Thermostable beta-glucosidase B K05350 bglB; beta-glucosidase [EC:3.2.1.21]
D R50_1415 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D R50_1821 fmdA; Formamidase K01455 fmdA; formamidase [EC:3.5.1.49]
C 00470 D-Amino acid metabolism [PATH:hfv00470]
D R50_1792 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D R50_0997 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D R50_2463 ddl; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D R50_1758 purQ; phosphoribosylformylglycinamidine synthetase subunit I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D R50_1489 murI; Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D R50_1007 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D R50_1022 dapF; Diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D R50_1189 lysA; meso-2,6-diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
C 00480 Glutathione metabolism [PATH:hfv00480]
D R50_1693 pxpA; oxoprolinase subunit A K07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9]
D R50_1362 pepA; putative cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D R50_0847 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D R50_1122 yqeC; Putative 6-phosphogluconate dehydrogenase K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D R50_0450 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D R50_1121 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D R50_0291 speE; Polyamine aminopropyltransferase K00797 speE; spermidine synthase [EC:2.5.1.16]
D R50_2747 speE; spermidine synthase; polyamine metabolism K00797 speE; spermidine synthase [EC:2.5.1.16]
B
B 09107 Glycan biosynthesis and metabolism
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:hfv00520]
D R50_2292 yfeU; putative PTS component; possibly regulatory K07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126]
D R50_2626 glmU; bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D R50_0320 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D R50_0962 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D R50_1772 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D R50_0961 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D R50_2666 Beta-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D R50_0039 agaA; N-acetylgalactosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
D R50_2290 putative BcrAD_BadFG domain-containing protein K18676 gspK; glucosamine kinase [EC:2.7.1.8]
D R50_1816 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D R50_1815 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D R50_1330 PfkB domain-containing protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D R50_1123 tal; Transaldolase K13810 tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9]
D R50_1124 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_2593 yngB; putative UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D R50_0333 tuaD; UDP-glucose 6-dehydrogenase TuaD K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D R50_0584 agl; UDP-sulfoquinovose synthase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D R50_0336 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D R50_0832 exoB; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D R50_2315 UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D R50_0197 UDP-galactopyranose mutase K01854 glf; UDP-galactopyranose mutase [EC:5.4.99.9]
D R50_0040 putative PTS sugar transporter subunit IIA K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D R50_0160 putative Mannose-1-phosphate guanylyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D R50_2594 Mannose-1-phosphate guanylyltransferase (GDP) K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D R50_0203 oleS; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
C 00541 Biosynthesis of various nucleotide sugars [PATH:hfv00541]
D R50_2626 glmU; bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D R50_2696 Gfo/Idh/MocA family oxidoreductase K13020 wlbA; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335]
D R50_0320 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D R50_1082 Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_1084 Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_2323 gmhA; Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_2325 Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_2593 yngB; putative UTP-glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D R50_0333 tuaD; UDP-glucose 6-dehydrogenase TuaD K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D R50_0203 oleS; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D R50_0201 spsJ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0334 NAD-dependent dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0202 spsL; putative dTDP-4-deoxyrhamnose-3,5-epimerase (cell surface and spore coat) K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D R50_0399 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D R50_0160 putative Mannose-1-phosphate guanylyltransferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D R50_2594 Mannose-1-phosphate guanylyltransferase (GDP) K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
D R50_0341 putative Glycosyl transferase group 1 K02840 waaB; UDP-D-galactose:(glucosyl)LPS alpha-1,6-D-galactosyltransferase [EC:2.4.1.-]
C 00542 O-Antigen repeat unit biosynthesis
C 00550 Peptidoglycan biosynthesis [PATH:hfv00550]
D R50_0962 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D R50_1772 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D R50_0961 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D R50_1774 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D R50_1007 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D R50_0662 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_0956 murE; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_2505 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_2463 ddl; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D R50_0957 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D R50_1253 uppS; undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D R50_0367 uppP; Undecaprenyl-diphosphatase 1 K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1382 uppP; Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1490 Phosphoesterase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_0958 mraY; phospho-N-acetylmuramoyl-pentapeptide undecaprenyl phosphate (C55P) transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D R50_0960 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D R50_1591 Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D R50_0959 spoVE; factor for spore cortex peptidoglycan synthesis (stage V sporulation) K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_2179 rodA; Peptidoglycan glycosyltransferase RodA K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_2486 Cell division protein FtsI (Peptidoglycan synthetase) K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D R50_0954 Cell division protein FtsI (Peptidoglycan synthetase) K08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein)
D R50_0955 Cell division protein FtsI (Peptidoglycan synthetase) K08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein)
D R50_0579 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1167 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1375 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1472 putative Lipid II isoglutaminyl synthase (glutamine-hydrolyzing) subunit MurT K23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
D R50_0744 protein of unknown function K07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]
C 00552 Teichoic acid biosynthesis [PATH:hfv00552]
D R50_0367 uppP; Undecaprenyl-diphosphatase 1 K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1382 uppP; Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1490 Phosphoesterase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_0822 Galactosyldiacylglycerol synthase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
D R50_1156 Galactosyldiacylglycerol synthase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:hfv00543]
D R50_0703 Serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:hfv00730]
D R50_0748 thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D R50_0819 thiD; Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D R50_1333 FAD-dependent glycine oxidase-like protein K03153 thiO; glycine oxidase [EC:1.4.3.19]
D R50_1149 dxs; 1-deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D R50_1335 thiG; hydroxyethylthiazole phosphate synthetase (thiamine biosynthesis) K03149 thiG; thiazole synthase [EC:2.8.1.10]
D R50_0820 thiE; Thiamine-phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D R50_1337 thiE; Thiamine-phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D R50_1781 thiL; Thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D R50_1676 rsgA; Small ribosomal subunit biogenesis GTPase RsgA K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D R50_2430 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:hfv00740]
D R50_2521 ribBA; fused 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D R50_2519 ribDG; fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino) uracil reductase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D R50_2522 ribH; 6,7-dimethyl-8-ribityllumazine synthase, beta subunit K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D R50_2520 ribE; Riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D R50_1269 FMN adenylyltransferase,Riboflavin kinase K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D R50_1016 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D R50_1162 ADP-ribose pyrophosphatase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C 00750 Vitamin B6 metabolism [PATH:hfv00750]
D R50_1353 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D R50_0009 pdxS; glutamine amidotransferase for pyridoxal phosphate synthesis; pyridoxal 5'-phosphate synthase complex, synthase subunit K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D R50_0010 pdxT; glutamine amidotransferase for pyridoxal phosphate synthesis; pyridoxal 5'-phosphate synthase complex, glutamine amidotransferase subunit PdxT K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:hfv00760]
D R50_2597 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D R50_2598 nadA; Quinolinate synthase A K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D R50_2596 nadC; nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase) K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D R50_1206 Nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D R50_1235 surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D R50_2169 nadD; putative nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D R50_0912 nadE; Glutamine-dependent NAD(+) synthetase K01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
D R50_2251 pncA; Nicotinamidase K08281 pncA; nicotinamidase/pyrazinamidase [EC:3.5.1.19 3.5.1.-]
D R50_1151 nadK; NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D R50_0059 gabD; putative succinate-semialdehyde dehydrogenase [NADP(+)] K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:hfv00770]
D R50_0814 ilvB; acetohydroxy-acid synthase (large subunit) K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D R50_0811 ilvC; acetohydroxy-acid isomeroreductase (NADP-dependent) K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D R50_0815 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D R50_0775 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D R50_0774 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D R50_1201 panC; Pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D R50_2517 coaX; Type III pantothenate kinase K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D R50_1026 coaBC; Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D R50_1623 coaD; phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D R50_1133 coaE; dephosphocoenzyme A kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D R50_1794 acpS; Holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D R50_0816 ilvE; Putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_2305 ilvE; putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_0428 Dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D R50_0427 Acyltransferase K01431 UPB1; beta-ureidopropionase [EC:3.5.1.6]
D R50_0492 panD; Aspartate 1-decarboxylase K01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]
C 00780 Biotin metabolism [PATH:hfv00780]
D R50_1609 fabF; beta-ketoacyl-acyl carrier protein synthase II (involved in pimelate synthesis) K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D R50_2601 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D R50_1611 fabG; beta-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_2750 Short-chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_0866 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D R50_2532 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D R50_2533 bioK; L-lysine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D R50_2534 bioD; ATP-dependent dethiobiotin synthetase BioD K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D R50_0115 bioB; biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
D R50_2523 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:hfv00785]
D R50_2754 lipB; Octanoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D R50_2755 lipA; lipoyl synthase (lipoic acid synthetase) K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D R50_2340 Elp3 domain-containing protein K09711 lipS1; lipoyl synthase
D R50_2341 Radical SAM protein K24689 lipS2; lipoyl synthase
D R50_1395 Lipoate-protein ligase A K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D R50_0683 Lipoate-protein ligase A K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D R50_2342 Biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D R50_2344 Ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2473 pdhA; Pyruvate dehydrogenase E1 component subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D R50_2472 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D R50_2471 putative Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D R50_0566 odhA; 2-oxoglutarate dehydrogenase, E1 subunit K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D R50_0567 odhB; 2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit) K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D R50_2758 bkdAA; branched-chain alpha-keto acid dehydrogenase E1 subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D R50_2759 bkdAA; branched-chain alpha-keto acid dehydrogenase E1 subunit K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D R50_2757 bkdAB; branched-chain alpha-keto acid dehydrogenase E1 subunit K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D R50_2756 bkdB; branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase) K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D R50_1419 gcvT; aminomethyltransferase (glycine cleavage system protein T) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D R50_0686 putative Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_0694 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1174 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1418 gcvH; glycine cleavage complex lipoylprotein K02437 gcvH; glycine cleavage system H protein
D R50_2343 gcvH; Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:hfv00790]
D R50_2102 folE; GTP cyclohydrolase FolE2 K09007 folE2; GTP cyclohydrolase IB [EC:3.5.4.16]
D R50_2524 7,8-dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D R50_2525 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D R50_2189 Dihydrofolate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D R50_2521 ribBA; fused 3,4-dihydroxy-2-butanone 4-phosphate synthase and GTP cyclohydrolase II K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D R50_1699 Para-aminobenzoate synthase, aminase component K01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]
D R50_1700 Aminodeoxychorismate lyase K02619 pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38]
D R50_1388 putative 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D R50_1865 Lactamase_B domain-containing protein K06897 K06897; 7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase [EC:2.5.1.105]
D R50_1683 moaA; GTP 3',8-cyclase K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D R50_1771 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D R50_2285 moaE; molybdopterin synthase (large subunit) K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D R50_2404 Molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D R50_2518 moeA; Molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D R50_2402 mobA; putative molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
D R50_2552 Nucleotidyltransferase family protein
C 00670 One carbon pool by folate [PATH:hfv00670]
D R50_1145 folD; methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D R50_1415 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D R50_1754 purN; Phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D R50_1753 purH; fused phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D R50_1799 Glutamate formimidoyltransferase K00603 fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
D R50_1419 gcvT; aminomethyltransferase (glycine cleavage system protein T) K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D R50_2705 5,10-methylenetetrahydrofolate reductase / Homolog of homocysteine-binding domain K24042 yitJ; methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
D R50_1540 thyX; Flavin-dependent thymidylate synthase K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D R50_1117 purU; formyltetrahydrofolate hydrolase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D R50_0643 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D R50_1229 S-inosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_0686 putative Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_0694 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1174 gcvH; Glycine cleavage system H protein 3 K02437 gcvH; glycine cleavage system H protein
D R50_1418 gcvH; glycine cleavage complex lipoylprotein K02437 gcvH; glycine cleavage system H protein
D R50_2343 gcvH; Glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D R50_0413 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
D R50_0742 mccB; Cystathionine gamma-lyase K17217 mccB; cystathionine gamma-lyase / homocysteine desulfhydrase [EC:4.4.1.1 4.4.1.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:hfv00860]
D R50_2670 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D R50_0852 hemA; Glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D R50_2288 hemL; glutamate-1-semialdehyde aminotransferase (aminomutase) K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D R50_2619 hemL; Glutamate-1-semialdehyde 2,1-aminomutase 1 K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D R50_0856 hemB; delta-aminolevulinic acid dehydratase (porphobilinogen synthase) K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D R50_0854 hemC; porphobilinogen deaminase (hydroxymethylbilane synthase) K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D R50_0093 hemE; uroporphyrinogen III decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D R50_0091 Protoporphyrinogen oxidase K00231 PPOX; protoporphyrinogen/coproporphyrinogen III oxidase [EC:1.3.3.4 1.3.3.15]
D R50_0092 hemH; Ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D R50_1549 Heme-dependent peroxidase K00435 hemQ; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
D R50_0855 putative Uroporphyrinogen-III synthase K13542 cobA-hemD; uroporphyrinogen III methyltransferase / synthase [EC:2.1.1.107 4.2.1.75]
D R50_0154 Radical SAM domain heme biosynthesis protein K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D R50_1635 ctaB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D R50_1633 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA K02259 COX15; heme a synthase [EC:1.17.99.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:hfv00130]
D R50_0707 Usp domain-containing protein K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D R50_0885 Methyltransferase type 12 K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D R50_0752 putative Salicylate biosynthesis isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D R50_0753 menD; 2-oxoglutarate decarboxylase and 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D R50_0754 menH; Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase K08680 menH; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [EC:4.2.99.20]
D R50_0114 menC; o-succinylbenzoate synthase K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D R50_0750 menE; 2-succinylbenzoate--CoA ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D R50_0749 menB; dihydroxynapthoic acid synthetase K01661 menB; naphthoate synthase [EC:4.1.3.36]
D R50_0751 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D R50_1825 NAD(P)H dehydrogenase (quinone) K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:hfv00900]
D R50_1149 dxs; 1-deoxyxylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D R50_1256 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D R50_2489 ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K12506 ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]
D R50_2631 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D R50_1258 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D R50_1855 ispH; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D R50_2653 Hydroxymethylglutaryl-CoA reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D R50_1148 ispA; farnesyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D R50_1828 Octaprenyl-diphosphate synthase K24873 hepT; heptaprenyl diphosphate synthase component 2 [EC:2.5.1.30]
D R50_1253 uppS; undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D R50_1691 tktA; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:hfv00523]
D R50_0203 oleS; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D R50_0201 spsJ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0334 NAD-dependent dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0202 spsL; putative dTDP-4-deoxyrhamnose-3,5-epimerase (cell surface and spore coat) K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D R50_0399 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D R50_0752 putative Salicylate biosynthesis isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C 01055 Biosynthesis of vancomycin group antibiotics
D R50_0201 spsJ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0334 NAD-dependent dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids [PATH:hfv00946]
D R50_0408 putative Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21]
D R50_2682 bglB; Thermostable beta-glucosidase B K05350 bglB; beta-glucosidase [EC:3.2.1.21]
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis [PATH:hfv00332]
D R50_1542 proB; Glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D R50_1541 proA; gamma-glutamyl phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:hfv00261]
D R50_1522 dapG; aspartokinase I (alpha and beta subunits) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_2607 lysCA; aspartokinase II alpha subunit (aa 1->408) K00928 lysC; aspartate kinase [EC:2.7.2.4]
D R50_1523 asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D R50_2526 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D R50_1474 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:hfv00521]
D R50_1124 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D R50_0613 algC; Phosphomannomutase/phosphoglucomutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D R50_0203 oleS; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D R50_0201 spsJ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0334 NAD-dependent dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0202 spsL; putative dTDP-4-deoxyrhamnose-3,5-epimerase (cell surface and spore coat) K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D R50_0399 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D R50_1124 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis [PATH:hfv00525]
D R50_0203 oleS; Glucose-1-phosphate thymidylyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D R50_0201 spsJ; dTDP-glucose 4,6-dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D R50_0334 NAD-dependent dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:hfv00401]
D R50_1658 Arogenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0081 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0732 hisC; Histidinol-phosphate aminotransferase 2 K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D R50_1668 trpE; anthranilate synthase K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D R50_1667 pabA; 4-amino-4-deoxychorismate synthase; anthranilate synthase (subunit II) K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D R50_1612 fabD; malonyl CoA:acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_2602 Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_1611 fabG; beta-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_2750 Short-chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_0866 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00975 Biosynthesis of various siderophores
C 00998 Biosynthesis of various antibiotics
D R50_1610 acpA; acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:hfv00999]
D R50_0643 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D R50_0408 putative Beta-glucosidase K05350 bglB; beta-glucosidase [EC:3.2.1.21]
D R50_2682 bglB; Thermostable beta-glucosidase B K05350 bglB; beta-glucosidase [EC:3.2.1.21]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:hfv00362]
D R50_0012 Carboxymuconolactone decarboxylase family protein K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D R50_0922 gcdC; Glutaconyl-CoA decarboxylase subunit gamma K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
C 00627 Aminobenzoate degradation
D R50_1804 putative Acylphosphate phosphohydrolase K01512 acyP; acylphosphatase [EC:3.6.1.7]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:hfv00625]
D R50_0411 adhA; putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D R50_0457 nifK; Nitrogenase molybdenum-iron protein beta chain K02591 nifK; nitrogenase molybdenum-iron protein beta chain [EC:1.18.6.1]
D R50_0459 nifH; Nitrogenase iron protein K02588 nifH; nitrogenase iron protein NifH
D R50_0458 nifD; Nitrogenase molybdenum-iron protein alpha chain K02586 nifD; nitrogenase molybdenum-iron protein alpha chain [EC:1.18.6.1]
D R50_1893 fdhA; Glutathione-independent formaldehyde dehydrogenase K00148 fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
D R50_1432 (2Fe-2S)-binding protein K16304 cmtAd; p-cumate 2,3-dioxygenase ferredoxin component
C 00633 Nitrotoluene degradation [PATH:hfv00633]
D R50_2282 hhyL; Hydrogenase large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D R50_2283 hhyS; Hydrogenase small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D R50_0939 cooS; Putative carbon monoxide dehydrogenase small subunit K00198 cooS; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4]
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation [PATH:hfv00791]
D R50_1286 Amidase domain-containing protein K19837 atzE; 1-carboxybiuret hydrolase [EC:3.5.1.131]
D R50_2259 ureC; Urease (alpha subunit) K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D R50_2260 ureB; Urease (beta subunit) K01429 ureB; urease subunit beta [EC:3.5.1.5]
D R50_2261 ureA; Urease (gamma subunit) K01430 ureA; urease subunit gamma [EC:3.5.1.5]
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:hfv00626]
D R50_0411 adhA; putative alcohol dehydrogenase AdhA K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:hfv03020]
D R50_2459 rpoB; RNA polymerase (beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D R50_2458 rpoC; RNA polymerase (beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D R50_2423 rpoA; RNA polymerase (alpha subunit) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D R50_1025 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
D R50_0474 DNA excision repair protein ERCC-3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:hfv03010]
D R50_RRNA2 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA4 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA6 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA8 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_1212 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D R50_1249 rpsB; ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D R50_2445 rpsC; ribosomal protein S3 (BS3) K02982 RP-S3; small subunit ribosomal protein S3
D R50_2424 rpsD; ribosomal protein S4 (BS4) K02986 RP-S4; small subunit ribosomal protein S4
D R50_2434 rpsE; ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D R50_2774 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D R50_2455 rpsG; ribosomal protein S7 (BS7) K02992 RP-S7; small subunit ribosomal protein S7
D R50_2437 rpsH; ribosomal protein S8 (BS8) K02994 RP-S8; small subunit ribosomal protein S8
D R50_2413 rpsI; ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D R50_2452 rpsJ; ribosomal protein S10 (BS13); transcription antitermination factor K02946 RP-S10; small subunit ribosomal protein S10
D R50_2425 rpsK; ribosomal protein S11 (BS11) K02948 RP-S11; small subunit ribosomal protein S11
D R50_2456 rpsL; ribosomal protein S12 (BS12) K02950 RP-S12; small subunit ribosomal protein S12
D R50_2426 rpsM; ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D R50_2438 rpsNA; ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D R50_1270 rpsO; ribosomal protein S15 (BS18) K02956 RP-S15; small subunit ribosomal protein S15
D R50_1585 rpsP; ribosomal protein S16 (BS17) K02959 RP-S16; small subunit ribosomal protein S16
D R50_2442 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D R50_2772 rpsR; ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D R50_2447 rpsS; ribosomal protein S19 (BS19) K02965 RP-S19; small subunit ribosomal protein S19
D R50_2145 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D R50_2133 rpsU; ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D R50_2465 rplA; ribosomal protein L1 (BL1) K02863 RP-L1; large subunit ribosomal protein L1
D R50_2448 rplB; ribosomal protein L2 (BL2) K02886 RP-L2; large subunit ribosomal protein L2
D R50_2451 rplC; ribosomal protein L3 (BL3) K02906 RP-L3; large subunit ribosomal protein L3
D R50_2450 rplD; ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D R50_2439 rplE; ribosomal protein L5 (BL6) K02931 RP-L5; large subunit ribosomal protein L5
D R50_2436 rplF; ribosomal protein L6 (BL8) K02933 RP-L6; large subunit ribosomal protein L6
D R50_2457 Putative ribosomal protein L7Ae-like K07590 RP-L7A; large subunit ribosomal protein L7A
D R50_2771 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D R50_2461 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D R50_2466 rplK; ribosomal protein L11 (BL11) K02867 RP-L11; large subunit ribosomal protein L11
D R50_2460 rplL; ribosomal protein L12 (BL9) K02935 RP-L7; large subunit ribosomal protein L7/L12
D R50_2414 rplM; ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D R50_2441 rplNA; ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D R50_2432 rplO; ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D R50_2444 rplP; ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D R50_2422 rplQ; ribosomal protein L17 (BL15) K02879 RP-L17; large subunit ribosomal protein L17
D R50_2435 rplR; ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D R50_1582 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D R50_0901 rplT; ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D R50_2174 rplU; ribosomal protein L21 (BL20) K02888 RP-L21; large subunit ribosomal protein L21
D R50_2446 rplV; ribosomal protein L22 (BL17) K02890 RP-L22; large subunit ribosomal protein L22
D R50_2449 rplW; ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D R50_2440 rplX; ribosomal protein L24 (BL23) K02895 RP-L24; large subunit ribosomal protein L24
D R50_2172 rpmA; ribosomal protein L27 (BL24) K02899 RP-L27; large subunit ribosomal protein L27
D R50_1672 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D R50_2443 rpmC; ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D R50_2433 rpmD; ribosomal protein L30 (BL27) K02907 RP-L30; large subunit ribosomal protein L30
D R50_0622 rpmEA; ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D R50_1617 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D R50_0900 rpmI; ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
C 00970 Aminoacyl-tRNA biosynthesis [PATH:hfv00970]
D R50_TRNA10 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D R50_TRNA15 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D R50_TRNA23 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D R50_TRNA2 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA4 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA40 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA42 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA31 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D R50_TRNA18 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D R50_TRNA21 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D R50_TRNA16 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D R50_TRNA51 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D R50_TRNA11 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D R50_TRNA50 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D R50_TRNA14 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA20 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA37 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA55 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA39 tRNA-His K14226 tRNA-His; tRNA His
D R50_TRNA29 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA30 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA47 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA49 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA24 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA27 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA28 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA38 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA48 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA12 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D R50_TRNA6 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D R50_TRNA32 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA44 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA7 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA8 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA19 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D R50_TRNA25 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA26 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA35 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA41 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA3 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D R50_TRNA52 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D R50_TRNA53 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D R50_TRNA43 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D R50_TRNA46 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D R50_TRNA54 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D R50_TRNA13 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D R50_TRNA45 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D R50_TRNA17 tRNA-Val K14237 tRNA-Val; tRNA Val
D R50_TRNA22 tRNA-Val K14237 tRNA-Val; tRNA Val
D R50_TRNA33 tRNA-Val K14237 tRNA-Val; tRNA Val
D R50_TRNA9 tRNA-Sec K14238 tRNA-Sec; tRNA Sec
D R50_2670 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D R50_1744 gatA; glutamyl-tRNA(Gln) amidotransferase (subunit A) K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D R50_1743 gatB; glutamyl-tRNA(Gln) amidotransferase (subunit B) K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D R50_1745 gatC; glutamyl-tRNA(Gln) amidotransferase (subunit C) K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D R50_1449 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D R50_1464 aspS; aspartyl-tRNA synthetase, promiscuous (also recognizes tRNAasn) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D R50_1377 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D R50_2119 glyQ; glycyl-tRNA synthetase (alpha subunit) K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D R50_2118 glyS; Glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D R50_0896 thrZ; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D R50_0011 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D R50_0858 selA; L-seryl-tRNA(Sec) selenium transferase K01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]
D R50_2485 cysS; dual cysteinyl-tRNA synthetase; cysteine persulfide synthase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D R50_2638 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D R50_1681 fmt; Methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D R50_2190 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D R50_2154 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D R50_0977 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D R50_2512 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D R50_2745 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D R50_1259 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D R50_2202 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D R50_0903 pheS; phenylalanyl-tRNA synthetase (alpha subunit) K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D R50_0904 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D R50_0908 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D R50_2462 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
D R50_1608 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:hfv03060]
D R50_2431 secY; preprotein translocase subunit K03076 secY; preprotein translocase subunit SecY
D R50_2468 Preprotein translocase subunit SecE (TC 3.A.5.1.1) K03073 secE; preprotein translocase subunit SecE
D R50_2217 secG; preprotein translocase subunit K03075 secG; preprotein translocase subunit SecG
D R50_0918 protein of unknown function K03210 yajC; preprotein translocase subunit YajC
D R50_2786 membrane protein of unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase
D R50_0650 secA; translocase binding subunit (ATPase) K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D R50_1586 ffh; signal recognition particle-like (SRP) GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D R50_1588 ftsY; signal recognition particle (docking protein) K03110 ftsY; fused signal recognition particle receptor
D R50_0746 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_1063 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_2650 Twin-arginine translocation protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_0829 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
D R50_0281 Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D R50_1581 Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D R50_0978 lspA; Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D R50_2335 protein of unknown function K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D R50_2336 exported protein of unknown function K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
D R50_0083 Heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D R50_2152 SHSP domain-containing protein K13993 HSP20; HSP20 family protein
D R50_2391 putative Heat shock protein Hsp20, HSP20 family protein K13993 HSP20; HSP20 family protein
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:hfv04122]
D R50_0467 putative sulfur-carrier protein (modular protein) K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D R50_0798 protein of unknown function K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D R50_0797 putative DrsE domain-containing protein K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D R50_1454 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D R50_2285 moaE; molybdopterin synthase (large subunit) K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D R50_1683 moaA; GTP 3',8-cyclase K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D R50_0460 putative Sulfur carrier protein CysO K03636 moaD; sulfur-carrier protein
D R50_2286 MoaD/ThiS family protein K03636 moaD; sulfur-carrier protein
D R50_1334 ThiF domain-containing protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D R50_0461 ttuC; Sulfur carrier protein adenylyltransferase K21147 moeZR; sulfur-carrier protein adenylyltransferase/sulfurtransferase [EC:2.7.7.80 2.7.7.- 2.8.1.11 2.8.1.-]
D R50_1771 moaC; molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D R50_1336 Thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein
C 03050 Proteasome
C 03018 RNA degradation [PATH:hfv03018]
D R50_2220 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D R50_1271 pnpA; polynucleotide phosphorylase (PNPase) K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D R50_2216 rnr; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D R50_1368 Cold-shock DEAD-box protein A K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D R50_0619 rho; transcriptional terminator Rho K03628 rho; transcription termination factor Rho
D R50_1387 rnjA; ribonuclease J1 K12574 rnj; ribonuclease J [EC:3.1.-.-]
D R50_1655 dnaK; molecular chaperone, ATP-dependent K04043 dnaK; molecular chaperone DnaK
D R50_1768 groEL; chaperonin large subunit K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:hfv03030]
D R50_0784 dnaE; Error-prone DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_1009 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_2676 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D R50_0003 Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2036 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2769 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D R50_2115 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D R50_2773 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50_0697 rnhA; Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D R50_1579 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D R50_1129 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D R50_1748 ligA; DNA ligase (NAD-dependent) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:hfv03410]
D R50_2728 nth; Endonuclease III (modular protein) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D R50_1441 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D R50_2363 Putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D R50_1130 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D R50_1494 putative DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D R50_2734 G:T/U mismatch-specific uracil/thymine DNA-glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
D R50_1783 udg; Type-4 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D R50_0410 nfo; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D R50_1129 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D R50_1467 conserved protein of unknown function K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D R50_1748 ligA; DNA ligase (NAD-dependent) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:hfv03420]
D R50_2623 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D R50_1849 uvrA; excinuclease ABC (subunit A) K03701 uvrA; excinuclease ABC subunit A
D R50_1850 uvrB; excinuclease ABC (subunit B) K03702 uvrB; excinuclease ABC subunit B
D R50_1848 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D R50_1749 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D R50_1129 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D R50_1748 ligA; DNA ligase (NAD-dependent) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D R50_0474 DNA excision repair protein ERCC-3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
C 03430 Mismatch repair [PATH:hfv03430]
D R50_1357 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D R50_0907 mutS; Endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D R50_1356 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D R50_1749 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D R50_1146 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D R50_1996 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D R50_1147 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D R50_1995 protein of unknown function K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D R50_1467 conserved protein of unknown function K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D R50_2773 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50_0784 dnaE; Error-prone DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_1009 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_0003 Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2036 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2676 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D R50_1748 ligA; DNA ligase (NAD-dependent) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D R50_0436 mjaIIIM; Modification methylase MjaIII K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2006 protein of unknown function K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2029 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C 03440 Homologous recombination [PATH:hfv03440]
D R50_1467 conserved protein of unknown function K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D R50_2773 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50_0004 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D R50_2120 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D R50_2674 recR; recA filament-DNA complex stabilisation factor K06187 recR; recombination protein RecR
D R50_1367 recA; multifunctional SOS repair factor K03553 recA; recombination protein RecA
D R50_1129 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D R50_0916 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D R50_0917 ruvB; Holliday junction DNA helicase, ATP-dependent component K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D R50_0915 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D R50_1669 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D R50_0784 dnaE; Error-prone DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_1009 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_0003 Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2036 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2676 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D R50_1027 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining [PATH:hfv03450]
D R50_1195 ku; Non-homologous end joining protein Ku K10979 ku; DNA end-binding protein Ku
D R50_1197 ATP-dependent DNA ligase clustered with Ku protein, LigD K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus and Alphavirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03273 Virion - Lassa virus and SFTS virus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:hfv02010]
D R50_1645 Metal-binding protein K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D R50_1646 membrane protein of unknown function K15496 wtpB; molybdate/tungstate transport system permease protein
D R50_2692 Glycine/betaine ABC transporter substrate-binding protein K15551 tauA; taurine transport system substrate-binding protein
D R50_2693 tauC; taurine transporter subunit; membrane component of ABC superfamily K15552 tauC; taurine transport system permease protein
D R50_1647 protein of unknown function K11084 phnT; 2-aminoethylphosphonate transport system ATP-binding protein
D R50_0758 LacI family transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein
D R50_0834 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) K10439 rbsB; ribose transport system substrate-binding protein
D R50_0757 ABC transporter permease K10440 rbsC; ribose transport system permease protein
D R50_0836 rbsC; ribose ABC transporter (permease) K10440 rbsC; ribose transport system permease protein
D R50_0835 rbsA; ribose ABC transporter (ATP-binding protein) K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]
D R50_0837 rbsD; D-ribose pyranase K06726 rbsD; D-ribose pyranase [EC:5.4.99.62]
D R50_0756 frcA; Fructose import ATP-binding protein FrcA K10554 frcA; fructose transport system ATP-binding protein
D R50_2230 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) K02037 pstC; phosphate transport system permease protein
D R50_2228 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) K02038 pstA; phosphate transport system permease protein
D R50_2227 pstBB; phosphate ABC transporter (ATP-binding protein) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D R50_1685 Biotin transporter K03523 bioY; biotin transport system substrate-specific component
D R50_0188 Transport permease protein K09690 wzm; homopolymeric O-antigen transport system permease protein
D R50_0189 ABC transporter domain-containing protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D R50_1479 ccmA; Heme ABC exporter ATP-binding protein CcmA K20490 nisF; lantibiotic transport system ATP-binding protein
D R50_1477 putative Cytochrome c-type biogenesis protein CcmC, heme lyase for CcmE K02195 ccmC; heme exporter protein C
D R50_1478 ABC transporter involved in cytochrome c biogenesis, CcmB subunit K02194 ccmB; heme exporter protein B
D R50_1320 Nitrous oxide reductase maturation transmembrane protein NosY K19341 nosY; Cu-processing system permease protein
D R50_1321 ABC transporter-like protein K19340 nosF; Cu-processing system ATP-binding protein
D R50_1851 Cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D R50_1852 ftsE; cell-division signal transducer (ATP-binding protein) K09812 ftsE; cell division transport system ATP-binding protein
D R50_0947 Transport ATP-binding protein CydC K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D R50_0946 Transport ATP-binding protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
D R50_0375 Macrolide export ATP-binding/permease protein MacB K05685 macB; macrolide transport system ATP-binding/permease protein [EC:7.6.2.-]
C 02060 Phosphotransferase system (PTS) [PATH:hfv02060]
D R50_0037 Phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D R50_0038 HPr family phosphocarrier protein K02784 ptsH; phosphocarrier protein HPr
D R50_0040 putative PTS sugar transporter subunit IIA K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
C 03070 Bacterial secretion system [PATH:hfv03070]
D R50_2468 Preprotein translocase subunit SecE (TC 3.A.5.1.1) K03073 secE; preprotein translocase subunit SecE
D R50_2217 secG; preprotein translocase subunit K03075 secG; preprotein translocase subunit SecG
D R50_2431 secY; preprotein translocase subunit K03076 secY; preprotein translocase subunit SecY
D R50_0918 protein of unknown function K03210 yajC; preprotein translocase subunit YajC
D R50_2786 membrane protein of unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase
D R50_0650 secA; translocase binding subunit (ATPase) K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D R50_1588 ftsY; signal recognition particle (docking protein) K03110 ftsY; fused signal recognition particle receptor
D R50_1586 ffh; signal recognition particle-like (SRP) GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D R50_0746 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_1063 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_2650 Twin-arginine translocation protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_0829 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:hfv02020]
D R50_2231 PAS domain-containing sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D R50_2575 putative Phosphate regulon transcriptional regulatory protein PhoB K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
D R50_0526 Flagellin K02406 fliC; flagellin
D R50_0498 Flagellar motor rotation protein MotA K02556 motA; chemotaxis protein MotA
D R50_1246 Osmosensitive K+ channel histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D R50_1245 kdpE; DNA-binding response regulator in two-component regulatory system with KdpD K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D R50_0096 kdpA; potassium translocating ATPase, subunit A K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
D R50_0097 kdpB; potassium translocating ATPase, subunit B K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
D R50_0098 kdpC; potassium translocating ATPase, subunit C K01548 kdpC; potassium-transporting ATPase KdpC subunit
D R50_1633 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA K02259 COX15; heme a synthase [EC:1.17.99.9]
D R50_0001 dnaA; chromosomal replication initiator informational ATPase K02313 dnaA; chromosomal replication initiator protein
D R50_2206 mprA; Response regulator MprA K11521 manR; two-component system, OmpR family, manganese sensing response regulator
D R50_1479 ccmA; Heme ABC exporter ATP-binding protein CcmA K20490 nisF; lantibiotic transport system ATP-binding protein
D R50_1158 spo0A; response regulator, phosphorylated in response to complex YlbF/YmcA/YaaT K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
D R50_0849 maeB; NADP-dependent malic enzyme (conversion of malate into pyruvate, anabolic) K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D R50_2252 putative Histidine kinase K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
D R50_2253 Two component transcriptional regulator, LytTR family K07705 lytT; two-component system, LytTR family, response regulator LytT
D R50_1501 narG; nitrate reductase (alpha subunit) K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D R50_1500 narH; nitrate reductase (beta subunit) K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D R50_1498 narI; nitrate reductase (gamma subunit) K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-]
D R50_1499 narJ; Nitrate reductase molybdenum cofactor assembly chaperone K00373 narJ; nitrate reductase molybdenum cofactor assembly chaperone NarJ/NarW
D R50_0532 csrA; Translational regulator CsrA K03563 csrA; carbon storage regulator
D R50_0780 putative Sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
D R50_0779 Two component transcriptional regulator, LuxR family K07693 desR; two-component system, NarL family, response regulator DesR
D R50_0591 conserved protein of unknown function K02651 flp; pilus assembly protein Flp/PilA
D R50_0592 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D R50_0377 conserved protein of unknown function K02282 cpaE; pilus assembly protein CpaE
D R50_0593 Pilus assembly protein CpaE K02282 cpaE; pilus assembly protein CpaE
D R50_0594 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1708 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1954 T2SP_E domain-containing protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1966 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_0381 Flp pilus assembly protein TadB K12510 tadB; tight adherence protein B
D R50_0595 Flp pilus assembly protein TadB K12510 tadB; tight adherence protein B
D R50_1125 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2306 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2283 hhyS; Hydrogenase small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D R50_2282 hhyL; Hydrogenase large subunit K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D R50_1066 hynC; Cytochrome b subunit K03620 hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit
D R50_0562 CheR-type methyltransferase domain-containing protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D R50_0385 CheW-like domain-containing protein K03408 cheW; purine-binding chemotaxis protein CheW
D R50_0386 Signal transduction histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D R50_0441 cheY; regulator of chemotaxis and motility K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D R50_0563 cheB; Protein-glutamate methylesterase/protein-glutamine glutaminase 1 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D R50_0940 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D R50_0789 cydA; cytochrome bb' ubiquinol oxidase (subunit I) K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_0890 cydA; cytochrome bb' ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_0944 cydA; cytochrome bb' ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_1315 cydA; cytochrome bb' ubiquinol oxidase, subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D R50_0891 cydB; cytochrome bb' ubiquinol oxidase (subunit II) K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_0945 cydB; cytochrome bb' ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_1033 membrane protein of unknown function K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_1316 cydB; cytochrome bb' ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D R50_1297 ptpA; Low molecular weight protein-tyrosine-phosphatase K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
D R50_0320 UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04082 Neuroactive ligand signaling
C 04081 Hormone signaling
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecule (CAM) interaction
C 04517 IgSF CAM signaling
C 04518 Integrin signaling
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome [PATH:hfv04146]
D R50_1570 Long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D R50_0847 icd; isocitrate dehydrogenase K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D R50_0733 sodB; Superoxide dismutase [Fe] K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D R50_2409 rocF; Arginase K01476 rocF; arginase [EC:3.5.3.1]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:hfv02024]
D R50_1668 trpE; anthranilate synthase K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D R50_1667 pabA; 4-amino-4-deoxychorismate synthase; anthranilate synthase (subunit II) K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D R50_1245 kdpE; DNA-binding response regulator in two-component regulatory system with KdpD K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D R50_1570 Long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D R50_0940 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D R50_2519 ribDG; fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino) uracil reductase K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D R50_1218 SBP_bac_5 domain-containing protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D R50_1216 appB; oligopeptide ABC transporter (permease) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D R50_1217 ABC transmembrane type-1 domain-containing protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D R50_1747 dppD; dipeptide ABC transporter (ATP-binding subunit) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D R50_1746 appF; oligopeptide ABC transporter (ATP-binding protein) K02032 ddpF; peptide/nickel transport system ATP-binding protein
D R50_2786 membrane protein of unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase
D R50_2468 Preprotein translocase subunit SecE (TC 3.A.5.1.1) K03073 secE; preprotein translocase subunit SecE
D R50_2217 secG; preprotein translocase subunit K03075 secG; preprotein translocase subunit SecG
D R50_2431 secY; preprotein translocase subunit K03076 secY; preprotein translocase subunit SecY
D R50_0918 protein of unknown function K03210 yajC; preprotein translocase subunit YajC
D R50_0650 secA; translocase binding subunit (ATPase) K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D R50_1588 ftsY; signal recognition particle (docking protein) K03110 ftsY; fused signal recognition particle receptor
D R50_1586 ffh; signal recognition particle-like (SRP) GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D R50_1158 spo0A; response regulator, phosphorylated in response to complex YlbF/YmcA/YaaT K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
D R50_0568 Phosphoesterase K01114 plc; phospholipase C [EC:3.1.4.3]
D R50_1479 ccmA; Heme ABC exporter ATP-binding protein CcmA K20490 nisF; lantibiotic transport system ATP-binding protein
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis [PATH:hfv02030]
D R50_0758 LacI family transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein
D R50_0834 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) K10439 rbsB; ribose transport system substrate-binding protein
D R50_0386 Signal transduction histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D R50_0385 CheW-like domain-containing protein K03408 cheW; purine-binding chemotaxis protein CheW
D R50_0441 cheY; regulator of chemotaxis and motility K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D R50_0440 Chemotaxis protein CheC --inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D R50_0563 cheB; Protein-glutamate methylesterase/protein-glutamine glutaminase 1 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D R50_0562 CheR-type methyltransferase domain-containing protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D R50_0504 fliG; flagellar motor switching and energizing component K02410 fliG; flagellar motor switch protein FliG
D R50_0530 Flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM
D R50_0438 Flagellar motor switch protein FliM K02417 fliN; flagellar motor switch protein FliN
D R50_0531 FliMN_C domain-containing protein K02417 fliN; flagellar motor switch protein FliN
D R50_0498 Flagellar motor rotation protein MotA K02556 motA; chemotaxis protein MotA
D R50_0499 Flagellar motor rotation protein MotB K02557 motB; chemotaxis protein MotB
C 02040 Flagellar assembly [PATH:hfv02040]
D R50_0502 Flagellar hook-basal body complex protein FliE K02408 fliE; flagellar hook-basal body complex protein FliE
D R50_0503 Flagellar M-ring protein K02409 fliF; flagellar M-ring protein FliF
D R50_0504 fliG; flagellar motor switching and energizing component K02410 fliG; flagellar motor switch protein FliG
D R50_0506 fliI; flagellar-specific ATPase subunit of export apparatus K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]
D R50_0530 Flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM
D R50_0438 Flagellar motor switch protein FliM K02417 fliN; flagellar motor switch protein FliN
D R50_0531 FliMN_C domain-containing protein K02417 fliN; flagellar motor switch protein FliN
D R50_0515 Flagellar protein (modular protein) K02418 fliO; flagellar protein FliO/FliZ
D R50_0516 fliP; component of the flagellar export machinery K02419 fliP; flagellar biosynthesis protein FliP
D R50_0517 fliQ; flagellar biosynthesis protein K02420 fliQ; flagellar biosynthesis protein FliQ
D R50_0518 Flagellar biosynthesis protein FliR K02421 fliR; flagellar biosynthesis protein FliR
D R50_0520 flhA; component of the flagellar export machinery K02400 flhA; flagellar biosynthesis protein FlhA
D R50_0519 Flagellar biosynthesis protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB
D R50_0500 Flagellar basal body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB
D R50_0501 flgC; flagellar component of cell-proximal portion of basal-body rod K02388 flgC; flagellar basal-body rod protein FlgC
D R50_0511 Flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD
D R50_0513 Flagellar hook protein flgE K02390 flgE; flagellar hook protein FlgE
D R50_0523 Flagellar basal-body rod protein flgG K02391 flgF; flagellar basal-body rod protein FlgF
D R50_0524 Flagellar basal body protein K02392 flgG; flagellar basal-body rod protein FlgG
D R50_0535 Flagellar hook-associated protein flgK K02396 flgK; flagellar hook-associated protein 1
D R50_0534 Flagellar hook-associated protein flgL K02397 flgL; flagellar hook-associated protein 3 FlgL
D R50_0526 Flagellin K02406 fliC; flagellin
D R50_0527 Flagellar hook-associated protein fliD K02407 fliD; flagellar hook-associated protein 2
D R50_0498 Flagellar motor rotation protein MotA K02556 motA; chemotaxis protein MotA
D R50_0499 Flagellar motor rotation protein MotB K02557 motB; chemotaxis protein MotB
D R50_2114 sigA; RNA polymerase major sigma-43 factor (sigma-A) K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D R50_2220 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04981 Folate transport and metabolism
D R50_1415 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
C 04382 Cornified envelope formation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:hfv01501]
D R50_2666 Beta-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D R50_1591 Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D R50_2486 Cell division protein FtsI (Peptidoglycan synthetase) K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
C 01502 Vancomycin resistance [PATH:hfv01502]
D R50_2463 ddl; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D R50_1792 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D R50_0957 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D R50_0958 mraY; phospho-N-acetylmuramoyl-pentapeptide undecaprenyl phosphate (C55P) transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D R50_0960 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:hfv01503]
D R50_2410 MurNAc-LAA domain-containing protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:hfv01000]
C 01001 Protein kinases [BR:hfv01001]
D R50_1677 Serine/threonine protein kinase PrkC, regulator of stationary phase K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D R50_2231 PAS domain-containing sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D R50_1246 Osmosensitive K+ channel histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D R50_1509 putative Histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D R50_0780 putative Sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
D R50_2252 putative Histidine kinase K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
D R50_0386 Signal transduction histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:hfv01009]
D R50_1229 S-inosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D R50_1678 prpC; multitarget phosphorylated protein phosphatase K20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]
C 01002 Peptidases and inhibitors [BR:hfv01002]
D R50_0978 lspA; Lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D R50_1649 gpr; Germination protease K06012 gpr; spore protease [EC:3.4.24.78]
D R50_1067 hupD; Hydrogenase maturation protein K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D R50_2270 Hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D R50_1763 guaA; GMP synthetase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D R50_1789 Peptidase C26 K07010 K07010; putative glutamine amidotransferase
D R50_1756 purF; glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D R50_0395 Glutamine amidotransferase type-2 domain-containing protein K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D R50_1815 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D R50_1391 asnO; Asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D R50_2113 Asparagine synthetase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D R50_0397 Protease I K05520 yhbO; deglycase [EC:3.5.1.124]
D R50_1896 Intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124]
D R50_1362 pepA; putative cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D R50_1363 putative Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D R50_2429 mapA; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D R50_2576 ftsH; ATP-dependent cytoplasmic membrane protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D R50_2699 ftsH; ATP-dependent cytoplasmic membrane protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D R50_2659 htpX; Protease HtpX homolog K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D R50_2176 Peptidase M50 K06402 spoIVFB; stage IV sporulation protein FB [EC:3.4.24.-]
D R50_1257 Membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D R50_0924 Peptidase M55 K16203 dppA1; D-amino peptidase [EC:3.4.11.-]
D R50_0579 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1167 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1375 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_2200 clpP; ATP-dependent Clp protease proteolytic subunit; Maxwell's demon K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D R50_2196 lonA; class III heat-shock ATP-dependent LonA protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D R50_2770 ATP-dependent protease LonB-like Type I K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D R50_2197 lonB; spore-specific ATP-dependent protease LonB K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D R50_1620 protein of unknown function K07177 K07177; Lon-like protease
D R50_1345 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D R50_0281 Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D R50_1581 Signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D R50_2335 protein of unknown function K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D R50_2336 exported protein of unknown function K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D R50_2380 tri; Tricorn protease homolog 1 K08676 tri; tricorn protease [EC:3.4.21.-]
D R50_1157 Stage IV sporulation protein B K06399 spoIVB; stage IV sporulation protein B [EC:3.4.21.116]
D R50_1574 clpQ; two-component ATP-dependent protease (N-terminal serine protease) K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
C 01003 Glycosyltransferases [BR:hfv01003]
D R50_0603 ppm; Polyprenol monophosphomannose synthase K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
D R50_0822 Galactosyldiacylglycerol synthase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
D R50_1156 Galactosyldiacylglycerol synthase K03429 ugtP; processive 1,2-diacylglycerol beta-glucosyltransferase [EC:2.4.1.315]
D R50_2388 mgtA; GDP-mannose-dependent alpha-mannosyltransferase K06119 SQD2; sulfoquinovosyltransferase [EC:2.4.1.-]
D R50_1591 Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D R50_0959 spoVE; factor for spore cortex peptidoglycan synthesis (stage V sporulation) K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_2179 rodA; Peptidoglycan glycosyltransferase RodA K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_1566 otsA; Trehalose-6-phosphate synthase K00697 otsA; trehalose 6-phosphate synthase [EC:2.4.1.15 2.4.1.347]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:hfv01005]
D R50_0341 putative Glycosyl transferase group 1 K02840 waaB; UDP-D-galactose:(glucosyl)LPS alpha-1,6-D-galactosyltransferase [EC:2.4.1.-]
D R50_1082 Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_1084 Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_2323 gmhA; Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
D R50_2325 Phosphoheptose isomerase K03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:hfv01011]
D R50_0962 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D R50_1772 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D R50_0961 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D R50_1774 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D R50_1007 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D R50_0662 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_0956 murE; UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_2505 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D R50_2463 ddl; D-alanine--D-alanine ligase K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D R50_1792 alr; Alanine racemase K01775 alr; alanine racemase [EC:5.1.1.1]
D R50_1489 murI; Glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D R50_0958 mraY; phospho-N-acetylmuramoyl-pentapeptide undecaprenyl phosphate (C55P) transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D R50_0960 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D R50_0367 uppP; Undecaprenyl-diphosphatase 1 K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1382 uppP; Undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1490 Phosphoesterase K19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]
D R50_1565 murJ; putative lipid II flippase MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D R50_1591 Multimodular transpeptidase-transglycosylase K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D R50_2486 Cell division protein FtsI (Peptidoglycan synthetase) K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D R50_0954 Cell division protein FtsI (Peptidoglycan synthetase) K08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein)
D R50_0955 Cell division protein FtsI (Peptidoglycan synthetase) K08384 spoVD; stage V sporulation protein D (sporulation-specific penicillin-binding protein)
D R50_0579 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1167 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_1375 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D R50_0959 spoVE; factor for spore cortex peptidoglycan synthesis (stage V sporulation) K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_2179 rodA; Peptidoglycan glycosyltransferase RodA K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_1134 Soluble lytic murein transglycosylase precursor K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D R50_1446 mltG; Endolytic murein transglycosylase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
D R50_1354 putative Gamma-D-glutamyl-meso-diaminopimelate peptidase K27245 sleB; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D R50_2410 MurNAc-LAA domain-containing protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:hfv01004]
D R50_1612 fabD; malonyl CoA:acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_2602 Malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D R50_1614 fabHA; beta-ketoacyl-acyl carrier protein synthase III 1 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D R50_1609 fabF; beta-ketoacyl-acyl carrier protein synthase II (involved in pimelate synthesis) K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D R50_2601 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D R50_1611 fabG; beta-ketoacyl-acyl carrier protein reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_2750 Short-chain dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D R50_0866 fabI; Enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D R50_0443 NADH:quinone reductase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D R50_2604 Enoyl-(acyl-carrier-protein) reductase [NADPH] K10780 fabL; enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104]
D R50_0085 acs; acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_2648 Acetyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D R50_1570 Long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D R50_1615 plsX; phosphate:acyl-ACP acyltransferase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D R50_1767 plsY; Glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D R50_1211 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:hfv01006]
D R50_1148 ispA; farnesyl diphosphate synthase K13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D R50_1828 Octaprenyl-diphosphate synthase K24873 hepT; heptaprenyl diphosphate synthase component 2 [EC:2.5.1.30]
D R50_1253 uppS; undecaprenyl pyrophosphate synthase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D R50_1355 miaA; delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D R50_0751 menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D R50_1635 ctaB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:hfv01007]
D R50_2670 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D R50_0908 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D R50_2462 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D R50_2485 cysS; dual cysteinyl-tRNA synthetase; cysteine persulfide synthase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D R50_2745 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D R50_2638 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D R50_0977 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D R50_2190 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D R50_2154 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D R50_2512 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D R50_1464 aspS; aspartyl-tRNA synthetase, promiscuous (also recognizes tRNAasn) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D R50_1377 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D R50_2202 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D R50_2119 glyQ; glycyl-tRNA synthetase (alpha subunit) K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D R50_2118 glyS; Glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D R50_0011 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D R50_1259 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D R50_0896 thrZ; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D R50_1449 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D R50_0903 pheS; phenylalanyl-tRNA synthetase (alpha subunit) K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D R50_0904 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D R50_1006 aspC; Aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D R50_0393 mtnE; Transaminase MtnE K08969 mtnE; L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase [EC:2.6.1.117]
D R50_2527 dapL; LL-diaminopimelate aminotransferase K10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]
D R50_0081 Histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_0732 hisC; Histidinol-phosphate aminotransferase 2 K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D R50_2532 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D R50_2301 argD; N-acetylornithine aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D R50_1392 gabT; 4-aminobutyrate aminotransferase K07250 gabT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase / 5-aminovalerate transaminase [EC:2.6.1.19 2.6.1.22 2.6.1.48]
D R50_1223 patA; Putrescine aminotransferase K09251 patA; putrescine aminotransferase [EC:2.6.1.82]
D R50_2533 bioK; L-lysine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D R50_2288 hemL; glutamate-1-semialdehyde aminotransferase (aminomutase) K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D R50_2619 hemL; Glutamate-1-semialdehyde 2,1-aminomutase 1 K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D R50_0997 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D R50_0816 ilvE; Putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D R50_2305 ilvE; putative branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:hfv00194]
D R50_0639 atpC; ATP synthase subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D R50_0638 atpD; ATP synthase subunit beta K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D R50_0637 atpG; ATP synthase subunit gamma K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D R50_0636 atpA; ATP synthase subunit alpha K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D R50_0635 atpH; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D R50_0634 atpF; ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D R50_0633 atpE; ATP synthase subunit c K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D R50_0632 atpB; ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:hfv03000]
D R50_1918 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2019 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_0263 rbcR; RuBisCO operon transcriptional regulator K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D R50_1593 rbcR; RuBisCO operon transcriptional regulator K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D R50_0642 spoIIID; transcriptional regulator (stage III sporulation) K06283 spoIIID; putative DeoR family transcriptional regulator, stage III sporulation protein D
D R50_0755 HTH lacI-type domain-containing protein K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D R50_0833 Ribose operon repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D R50_0041 dasR; HTH-type transcriptional repressor DasR K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
D R50_1765 MerR family transcriptional regulator K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
D R50_1656 protein of unknown function K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D R50_2561 MerR family transcriptional regulator K21902 yfmP; MerR family transcriptional regulator, repressor of the yfmOP operon
D R50_0607 Transcriptional repressor K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D R50_2405 fur; transcriptional regulator for iron transport and metabolism K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D R50_1784 Fur family transcriptional regulator K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D R50_0940 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D R50_0133 ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D R50_2540 ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D R50_0138 Transcriptional regulator K21885 cmtR; ArsR family transcriptional regulator, cadmium/lead-responsive transcriptional repressor
D R50_0581 mntR; transcriptional regulator (hydrogen peroxide sensing, allosterically regulated by Mn2+) K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
D R50_2523 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D R50_2629 purR; transcriptional regulator of the purine biosynthesis operon (PurR-pRpp) K09685 purR; HTH-type transcriptional regulator, purine operon repressor
D R50_2737 putative Fis family transcriptional regulator K06714 rocR; arginine utilization regulatory protein
D R50_1827 rex; Redox-sensing transcriptional repressor Rex K01926 rex; redox-sensing transcriptional repressor
D R50_1572 codY; transcriptional regulator, GTP and BCAA-dependent K03706 codY; transcriptional pleiotropic repressor
D R50_1791 RHH_1 domain-containing protein K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI
D R50_0234 csoR; Copper-sensing transcriptional repressor CsoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D R50_2244 Metal-sensitive transcriptional regulator K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D R50_2096 AbrB family transcriptional regulator K06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes
D R50_2640 AbrB family transcriptional regulator K06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes
D R50_2621 spoVT; transcriptional regulator of sporulation / germination K04769 spoVT; AbrB family transcriptional regulator, stage V sporulation protein T
D R50_2783 parB; site-specific DNA-binding protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D R50_1152 argR; transcriptional regulator (AhrC(ArgR)-arginine) K03402 argR; transcriptional regulator of arginine metabolism
D R50_2139 hrcA; Heat-inducible transcription repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor
D R50_2498 ctsR; transcriptional regulator of class III stress genes K03708 ctsR; transcriptional regulator of stress and heat shock response
D R50_0982 pyrR; transcriptional attenuator and uracil phosphoribosyltransferase activity K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D R50_1702 nrdR; negative regulator of transcription of ribonucleotide reductase nrd genes and operons K07738 nrdR; transcriptional repressor NrdR
D R50_1724 nrdR; negative regulator of transcription of ribonucleotide reductase nrd genes and operons K07738 nrdR; transcriptional repressor NrdR
D R50_0951 mraZ; inhibitor of RsmH and transcriptional regulator K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:hfv03021]
D R50_0474 DNA excision repair protein ERCC-3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D R50_2423 rpoA; RNA polymerase (alpha subunit) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D R50_2459 rpoB; RNA polymerase (beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D R50_2458 rpoC; RNA polymerase (beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D R50_1025 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D R50_2114 sigA; RNA polymerase major sigma-43 factor (sigma-A) K03086 rpoD; RNA polymerase primary sigma factor
D R50_1340 RNA polymerase sigma-70 factor, ECF subfamily K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily
D R50_2239 RNA polymerase sigma factor K03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily
D R50_0968 sigE; RNA polymerase sporulation-specific sigma-29 factor (sigma-E) K03091 sigE_F_G; RNA polymerase sigma-E/F/G factor
D R50_0969 sigG; RNA polymerase sporulation-specific sigma factor (sigma-G) K03091 sigE_F_G; RNA polymerase sigma-E/F/G factor
D R50_1183 sigF; RNA polymerase sporulation-specific sigma factor (sigma-F) K03091 sigE_F_G; RNA polymerase sigma-E/F/G factor
D R50_1438 sigK; RNA polymerase sigma-28 factor K03091 sigE_F_G; RNA polymerase sigma-E/F/G factor
D R50_0218 sigH; RNA polymerase sigma-H factor K27000 sigH; RNA polymerase sigma-H factor
D R50_2483 sigH; RNA polymerase sigma-30 factor (sigma(H)) K27000 sigH; RNA polymerase sigma-H factor
D R50_1263 nusA; transcription translation coupling factor involved in Rho-dependent transcription termination K02600 nusA; transcription termination/antitermination protein NusA
D R50_1143 nusB; Transcription antitermination protein NusB K03625 nusB; transcription antitermination protein NusB
D R50_2467 nusG; RNA polymerase elongation pause factor K02601 nusG; transcription termination/antitermination protein NusG
D R50_2513 greA; transcription elongation factor resolving backtracking / stalling K03624 greA; transcription elongation factor GreA
D R50_0619 rho; transcriptional terminator Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:hfv03019]
D R50_2175 Cytoplasmic axial filament protein CafA and Ribonuclease G K08301 rng; ribonuclease G [EC:3.1.26.-]
D R50_1608 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D R50_1387 rnjA; ribonuclease J1 K12574 rnj; ribonuclease J [EC:3.1.-.-]
D R50_2216 rnr; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D R50_1368 Cold-shock DEAD-box protein A K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D R50_2220 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D R50_1271 pnpA; polynucleotide phosphorylase (PNPase) K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D R50_0619 rho; transcriptional terminator Rho K03628 rho; transcription termination factor Rho
D R50_1655 dnaK; molecular chaperone, ATP-dependent K04043 dnaK; molecular chaperone DnaK
D R50_1768 groEL; chaperonin large subunit K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D R50_0532 csrA; Translational regulator CsrA K03563 csrA; carbon storage regulator
D R50_1846 yvcJ; GTPase possibly involved in regulator sRNA degradation K06958 rapZ; RNase adapter protein RapZ
C 03041 Spliceosome
C 03011 Ribosome [BR:hfv03011]
D R50_1212 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D R50_1249 rpsB; ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D R50_2445 rpsC; ribosomal protein S3 (BS3) K02982 RP-S3; small subunit ribosomal protein S3
D R50_2424 rpsD; ribosomal protein S4 (BS4) K02986 RP-S4; small subunit ribosomal protein S4
D R50_2434 rpsE; ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D R50_2774 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D R50_2455 rpsG; ribosomal protein S7 (BS7) K02992 RP-S7; small subunit ribosomal protein S7
D R50_2437 rpsH; ribosomal protein S8 (BS8) K02994 RP-S8; small subunit ribosomal protein S8
D R50_2413 rpsI; ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D R50_2452 rpsJ; ribosomal protein S10 (BS13); transcription antitermination factor K02946 RP-S10; small subunit ribosomal protein S10
D R50_2425 rpsK; ribosomal protein S11 (BS11) K02948 RP-S11; small subunit ribosomal protein S11
D R50_2456 rpsL; ribosomal protein S12 (BS12) K02950 RP-S12; small subunit ribosomal protein S12
D R50_2426 rpsM; ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D R50_2438 rpsNA; ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D R50_1270 rpsO; ribosomal protein S15 (BS18) K02956 RP-S15; small subunit ribosomal protein S15
D R50_1585 rpsP; ribosomal protein S16 (BS17) K02959 RP-S16; small subunit ribosomal protein S16
D R50_2442 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D R50_2772 rpsR; ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D R50_2447 rpsS; ribosomal protein S19 (BS19) K02965 RP-S19; small subunit ribosomal protein S19
D R50_2145 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D R50_2133 rpsU; ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D R50_2465 rplA; ribosomal protein L1 (BL1) K02863 RP-L1; large subunit ribosomal protein L1
D R50_2448 rplB; ribosomal protein L2 (BL2) K02886 RP-L2; large subunit ribosomal protein L2
D R50_2451 rplC; ribosomal protein L3 (BL3) K02906 RP-L3; large subunit ribosomal protein L3
D R50_2450 rplD; ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D R50_2439 rplE; ribosomal protein L5 (BL6) K02931 RP-L5; large subunit ribosomal protein L5
D R50_2436 rplF; ribosomal protein L6 (BL8) K02933 RP-L6; large subunit ribosomal protein L6
D R50_2771 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D R50_2461 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D R50_2466 rplK; ribosomal protein L11 (BL11) K02867 RP-L11; large subunit ribosomal protein L11
D R50_2460 rplL; ribosomal protein L12 (BL9) K02935 RP-L7; large subunit ribosomal protein L7/L12
D R50_2414 rplM; ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D R50_2441 rplNA; ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D R50_2432 rplO; ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D R50_2444 rplP; ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D R50_2422 rplQ; ribosomal protein L17 (BL15) K02879 RP-L17; large subunit ribosomal protein L17
D R50_2435 rplR; ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D R50_1582 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D R50_0901 rplT; ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D R50_2174 rplU; ribosomal protein L21 (BL20) K02888 RP-L21; large subunit ribosomal protein L21
D R50_2446 rplV; ribosomal protein L22 (BL17) K02890 RP-L22; large subunit ribosomal protein L22
D R50_2449 rplW; ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D R50_2440 rplX; ribosomal protein L24 (BL23) K02895 RP-L24; large subunit ribosomal protein L24
D R50_2172 rpmA; ribosomal protein L27 (BL24) K02899 RP-L27; large subunit ribosomal protein L27
D R50_1672 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D R50_2443 rpmC; ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D R50_2433 rpmD; ribosomal protein L30 (BL27) K02907 RP-L30; large subunit ribosomal protein L30
D R50_0622 rpmEA; ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D R50_1617 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D R50_0900 rpmI; ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D R50_2457 Putative ribosomal protein L7Ae-like K07590 RP-L7A; large subunit ribosomal protein L7A
D R50_RRNA2 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA4 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA6 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA8 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
C 03009 Ribosome biogenesis [BR:hfv03009]
D R50_1608 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D R50_2121 era; maturation of 16S RNA and assembly of 30S ribosomal subunit GTPase K03595 era; GTPase
D R50_2170 obgE; ppGpp-binding GTPase involved in cell partitioning, DNA repair and ribosome assembly K03979 obgE; GTPase [EC:3.6.5.-]
D R50_1263 nusA; transcription translation coupling factor involved in Rho-dependent transcription termination K02600 nusA; transcription termination/antitermination protein NusA
D R50_1143 nusB; Transcription antitermination protein NusB K03625 nusB; transcription antitermination protein NusB
D R50_2467 nusG; RNA polymerase elongation pause factor K02601 nusG; transcription termination/antitermination protein NusG
D R50_2635 rsmA; Ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D R50_1680 Ribosomal RNA small subunit methyltransferase B K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D R50_2785 rsmG; Ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D R50_0952 rsmH; 16S rRNA m4C1402 methyltransferase K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D R50_2641 rsmI; Ribosomal RNA small subunit methyltransferase I K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D R50_1150 yqxC; putative 2'-O-ribose RNA methyltransferase K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D R50_2484 23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D R50_2763 rlmH; Ribosomal RNA large subunit methyltransferase H K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D R50_2669 LSU m5C1962 methyltransferase RlmI K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D R50_1679 rlmN; 23S rRNA m2A2503 methyltransferase and tRNA A37 C2 methyltransferase K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D R50_1742 RNA methyltransferase, TrmA family K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D R50_1205 Ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D R50_0979 rluD; pseudouridylate synthase K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D R50_0664 Ribosomal-protein-S18p-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D R50_1778 rimI; ribosomal protein S18 alanine N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D R50_1584 rimM; Ribosome maturation factor RimM K02860 rimM; 16S rRNA processing protein RimM
D R50_1373 rimO; Ribosomal protein S12 methylthiotransferase RimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
D R50_2136 prmA; Ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
D R50_2175 Cytoplasmic axial filament protein CafA and Ribonuclease G K08301 rng; ribonuclease G [EC:3.1.26.-]
D R50_1447 pre-16S ribosomal RNA maturation enzyme (modular protein) K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D R50_1368 Cold-shock DEAD-box protein A K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D R50_1676 rsgA; Small ribosomal subunit biogenesis GTPase RsgA K06949 rsgA; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]
D R50_1213 der; GTPase essential for ribosome 50S subunit assembly (maturation of the 50S subunit central protoberance) K03977 engA; GTPase
D R50_1580 Ribosome biogenesis GTPase A K14540 rbgA; ribosome biogenesis GTPase A
D R50_0626 tsaC; tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; threonine-dependent ADP-forming ATPase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D R50_1466 rsh; GTP pyrophosphokinase (RelA/SpoT) K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D R50_1267 rbfA; pre-ribosomal (17S) RNA binding factor A K02834 rbfA; ribosome-binding factor A
D R50_2124 rnrY; endonuclease involved in 70S ribosomes quality control K07042 ybeY; probable rRNA maturation factor
D R50_0647 hpf; Ribosome hibernation promotion factor K05808 hpf; ribosome hibernation promoting factor
D R50_2289 ychF; Ribosome-binding ATPase YchF K06942 ychF; ribosome-binding ATPase
D R50_1618 conserved protein of unknown function K07040 yceD; DUF177 domain-containing protein
C 03016 Transfer RNA biogenesis [BR:hfv03016]
D R50_2411 putative PolyA_pol domain-containing protein K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
D R50_2670 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D R50_1259 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D R50_0977 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D R50_2154 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D R50_2638 metS; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D R50_2745 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D R50_2512 lysS; lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D R50_1464 aspS; aspartyl-tRNA synthetase, promiscuous (also recognizes tRNAasn) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D R50_1449 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D R50_1377 asnS; asparaginyl-tRNA synthetase K01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]
D R50_0896 thrZ; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D R50_0011 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D R50_2485 cysS; dual cysteinyl-tRNA synthetase; cysteine persulfide synthase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D R50_2190 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D R50_2202 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D R50_0903 pheS; phenylalanyl-tRNA synthetase (alpha subunit) K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D R50_0904 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D R50_0908 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D R50_2462 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D R50_1465 dtd; gly-tRNA(Ala) deacylase / D-Tyr-tRNATyr deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D R50_2134 Uncharacterized HIT-like protein aq_141 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D R50_1243 miaB; tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase K06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D R50_2421 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D R50_1268 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D R50_0626 tsaC; tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; threonine-dependent ADP-forming ATPase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D R50_1355 miaA; delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D R50_0656 selD; Selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D R50_2788 rnpA; Ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D R50_MISCRNA171 RNaseP_bact_a K01978 rnpB; RNase P catalytic RNA component
D R50_2211 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D R50_2119 glyQ; glycyl-tRNA synthetase (alpha subunit) K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D R50_2118 glyS; Glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D R50_2678 tadA; tRNA specific adenosine A34 deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D R50_1577 trmFO; tRNA:m(5)U-54 methyltransferase K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D R50_1583 trmD; tRNA(m1G37)methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D R50_0998 trmL; tRNA (cytidine(34)-2'-O)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D R50_0902 RNA methyltransferase K03437 spoU; RNA methyltransferase, TrmH family
D R50_1454 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D R50_0467 putative sulfur-carrier protein (modular protein) K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D R50_0798 protein of unknown function K07237 tusB; tRNA 2-thiouridine synthesizing protein B
D R50_0797 putative DrsE domain-containing protein K07236 tusC; tRNA 2-thiouridine synthesizing protein C
D R50_2584 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D R50_1779 putative Inactive homolog of metal-dependent proteases, molecular chaperone K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D R50_1776 tsaD; tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; glycation binding protein K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D R50_1780 ATPase YjeE, predicted to have essential role in cell wall biosynthesis K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D R50_2216 rnr; Ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D R50_1271 pnpA; polynucleotide phosphorylase (PNPase) K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:hfv03012]
D R50_1266 infB; Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D R50_0899 infC; initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D R50_1250 tsf; Elongation factor Ts K02357 tsf; elongation factor Ts
D R50_2453 tufA; elongation factor Tu K02358 tuf; elongation factor Tu
D R50_2454 fusA; elongation factor G K02355 fusA; elongation factor G
D R50_1470 selB; Selenocysteine-specific elongation factor K03833 selB; selenocysteine-specific elongation factor
D R50_0623 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D R50_1252 frr; ribosome recycling factor K02838 frr; ribosome recycling factor
D R50_0624 prmC; Release factor glutamine methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D R50_2624 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D R50_2427 infA; initiation factor IF-I K02518 infA; translation initiation factor IF-1
D R50_1412 efp; elongation factor P K02356 efp; elongation factor P
D R50_0651 prfB; Peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:hfv03110]
D R50_1653 clpB; protein disaggregation chaperone K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D R50_2495 clpC; class III stress response-related ATPase, AAA+ superfamily; Maxwell's demon K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC
D R50_2199 clpX; protein unfolding ATPase required for presentation of proteins to proteases; Maxwell's demon K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D R50_1573 clpY; two-component ATP-dependent protease (ATPase and chaperone) K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D R50_1655 dnaK; molecular chaperone, ATP-dependent K04043 dnaK; molecular chaperone DnaK
D R50_1768 groEL; chaperonin large subunit K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D R50_1654 Molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D R50_2137 dnaJ; co-factor of molecular chaperone K03686 dnaJ; molecular chaperone DnaJ
D R50_1673 hslO; 33 kDa chaperonin K04083 hslO; molecular chaperone Hsp33
D R50_2138 grpE; Protein GrpE K03687 GRPE; molecular chaperone GrpE
D R50_0083 Heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D R50_2152 SHSP domain-containing protein K13993 HSP20; HSP20 family protein
D R50_2391 putative Heat shock protein Hsp20, HSP20 family protein K13993 HSP20; HSP20 family protein
D R50_1769 groES; chaperonin small subunit K04078 groES; chaperonin GroES
D R50_2191 groS; 10 kDa chaperonin K04078 groES; chaperonin GroES
D R50_2576 ftsH; ATP-dependent cytoplasmic membrane protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D R50_2699 ftsH; ATP-dependent cytoplasmic membrane protease K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D R50_0632 atpB; ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D R50_1072 hypA; Hydrogenase maturation factor K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D R50_2277 hypA; Hydrogenase maturation factor K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D R50_2276 HypB; Hydrogen maturation factor K04652 hypB; hydrogenase nickel incorporation protein HypB
D R50_2622 Peptidylprolyl isomerase K07533 prsA; foldase protein PrsA [EC:5.2.1.8]
D R50_1461 trxA; thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:hfv04131]
D R50_1226 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D R50_1370 AAA domain-containing protein K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D R50_2234 membrane protein of unknown function K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D R50_2224 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D R50_0996 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:hfv03032]
D R50_0697 rnhA; Ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D R50_1918 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2019 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2617 hbs; non-specific DNA-binding protein HBsu K03530 hupB; DNA-binding protein HU-beta
D R50_0001 dnaA; chromosomal replication initiator informational ATPase K02313 dnaA; chromosomal replication initiator protein
D R50_2769 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D R50_2115 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D R50_2773 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50_0784 dnaE; Error-prone DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_1009 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_0003 Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2036 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2676 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D R50_1579 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D R50_1129 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D R50_1748 ligA; DNA ligase (NAD-dependent) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D R50_0436 mjaIIIM; Modification methylase MjaIII K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2006 protein of unknown function K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2029 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_0008 gyrA; DNA gyrase (subunit A) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D R50_0007 gyrB; DNA gyrase (subunit B) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D R50_1578 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:hfv03036]
D R50_1918 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2019 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_1608 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D R50_2617 hbs; non-specific DNA-binding protein HBsu K03530 hupB; DNA-binding protein HU-beta
D R50_0001 dnaA; chromosomal replication initiator informational ATPase K02313 dnaA; chromosomal replication initiator protein
D R50_1589 smc; Chromosome partition protein Smc K03529 smc; chromosome segregation protein
D R50_1192 scpB; Segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D R50_0965 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA
D R50_1852 ftsE; cell-division signal transducer (ATP-binding protein) K09812 ftsE; cell division transport system ATP-binding protein
D R50_1381 Cell division protein FtsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D R50_0959 spoVE; factor for spore cortex peptidoglycan synthesis (stage V sporulation) K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_1851 Cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D R50_0966 ftsZ; cell-division initiation protein K03531 ftsZ; cell division protein FtsZ
D R50_0905 Cell division protein ZapA K09888 zapA; cell division protein ZapA
D R50_2410 MurNAc-LAA domain-containing protein K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D R50_0609 minC; putative septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D R50_2182 minC; Septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D R50_2181 minD; ATPase activator of MinC K03609 minD; septum site-determining protein MinD
D R50_2180 minE; Cell division topological specificity factor K03608 minE; cell division topological specificity factor
D R50_0976 divIVA; cell-division initiation protein K04074 divIVA; cell division initiation protein
D R50_0974 sepF; Cell division protein SepF K09772 sepF; cell division inhibitor SepF
D R50_2185 mreB; cell-shape determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D R50_2184 Cell shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D R50_2179 rodA; Peptidoglycan glycosyltransferase RodA K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_2784 parA; chromosome partitioning protein; transcriptional regulator K03496 parA; chromosome partitioning protein
D R50_2783 parB; site-specific DNA-binding protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D R50_2785 rsmG; Ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D R50_1577 trmFO; tRNA:m(5)U-54 methyltransferase K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D R50_1165 ripX; site-specific tyrosine recombinase for chromosome partitioning K04763 xerD; integrase/recombinase XerD
D R50_0589 mrp; Iron-sulfur cluster carrier protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D R50_2195 engB; putative GTP-binding protein EngB K03978 engB; GTP-binding protein
D R50_1844 whiA; Putative sporulation transcription regulator WhiA K09762 whiA; cell division protein WhiA
C 03400 DNA repair and recombination proteins [BR:hfv03400]
D R50_2731 putative Methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D R50_2363 Putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D R50_1441 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D R50_2728 nth; Endonuclease III (modular protein) K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D R50_0474 DNA excision repair protein ERCC-3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D R50_0711 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50_1241 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D R50_0577 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D R50_2734 G:T/U mismatch-specific uracil/thymine DNA-glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
D R50_1783 udg; Type-4 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D R50_1494 putative DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D R50_1130 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D R50_0410 nfo; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D R50_1467 conserved protein of unknown function K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D R50_1748 ligA; DNA ligase (NAD-dependent) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D R50_1129 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D R50_1849 uvrA; excinuclease ABC (subunit A) K03701 uvrA; excinuclease ABC subunit A
D R50_1850 uvrB; excinuclease ABC (subunit B) K03702 uvrB; excinuclease ABC subunit B
D R50_1848 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D R50_1749 pcrA; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D R50_2459 rpoB; RNA polymerase (beta subunit) K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D R50_2458 rpoC; RNA polymerase (beta' subunit) K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D R50_2423 rpoA; RNA polymerase (alpha subunit) K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D R50_1025 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D R50_2623 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D R50_1357 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D R50_0907 mutS; Endonuclease MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D R50_1356 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D R50_1146 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D R50_1996 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D R50_1147 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D R50_1995 protein of unknown function K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D R50_0784 dnaE; Error-prone DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_1009 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D R50_0003 Beta sliding clamp K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2036 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D R50_2676 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D R50_2773 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50_0436 mjaIIIM; Modification methylase MjaIII K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2006 protein of unknown function K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2029 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_1917 Very-short-patch mismatch repair endonuclease (G-T specific) K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
D R50_1367 recA; multifunctional SOS repair factor K03553 recA; recombination protein RecA
D R50_0916 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D R50_0917 ruvB; Holliday junction DNA helicase, ATP-dependent component K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D R50_0915 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D R50_1027 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D R50_0004 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D R50_1669 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D R50_2120 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D R50_2674 recR; recA filament-DNA complex stabilisation factor K06187 recR; recombination protein RecR
D R50_1153 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D R50_0074 cas1; CRISPR-associated endonuclease Cas1 2 K15342 cas1; CRISP-associated protein Cas1
D R50_1195 ku; Non-homologous end joining protein Ku K10979 ku; DNA end-binding protein Ku
D R50_1197 ATP-dependent DNA ligase clustered with Ku protein, LigD K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D R50_0008 gyrA; DNA gyrase (subunit A) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D R50_0007 gyrB; DNA gyrase (subunit B) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D R50_1578 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D R50_2617 hbs; non-specific DNA-binding protein HBsu K03530 hupB; DNA-binding protein HU-beta
D R50_1345 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D R50_1366 recX; Regulatory protein RecX K03565 recX; regulatory protein
D R50_1234 DinG family ATP-dependent helicase YoaA K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D R50_0273 nrdA; Ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D R50_0272 nrdB; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:hfv03029]
D R50_1266 infB; Translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D R50_0899 infC; initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D R50_1250 tsf; Elongation factor Ts K02357 tsf; elongation factor Ts
D R50_2453 tufA; elongation factor Tu K02358 tuf; elongation factor Tu
D R50_2454 fusA; elongation factor G K02355 fusA; elongation factor G
D R50_2121 era; maturation of 16S RNA and assembly of 30S ribosomal subunit GTPase K03595 era; GTPase
D R50_0908 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D R50_2154 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D R50_1464 aspS; aspartyl-tRNA synthetase, promiscuous (also recognizes tRNAasn) K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D R50_2745 argS; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D R50_1744 gatA; glutamyl-tRNA(Gln) amidotransferase (subunit A) K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D R50_1743 gatB; glutamyl-tRNA(Gln) amidotransferase (subunit B) K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D R50_1745 gatC; glutamyl-tRNA(Gln) amidotransferase (subunit C) K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D R50_2773 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D R50_1655 dnaK; molecular chaperone, ATP-dependent K04043 dnaK; molecular chaperone DnaK
D R50_2138 grpE; Protein GrpE K03687 GRPE; molecular chaperone GrpE
D R50_1768 groEL; chaperonin large subunit K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D R50_1769 groES; chaperonin small subunit K04078 groES; chaperonin GroES
D R50_2191 groS; 10 kDa chaperonin K04078 groES; chaperonin GroES
D R50_1654 Molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D R50_2137 dnaJ; co-factor of molecular chaperone K03686 dnaJ; molecular chaperone DnaJ
D R50_0589 mrp; Iron-sulfur cluster carrier protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D R50_1635 ctaB; Protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D R50_1633 Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA K02259 COX15; heme a synthase [EC:1.17.99.9]
D R50_2786 membrane protein of unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:hfv02000]
D R50_1698 Multidrug ABC transporter ATPase K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D R50_0947 Transport ATP-binding protein CydC K16012 cydC; ATP-binding cassette, subfamily C, bacterial CydC
D R50_0946 Transport ATP-binding protein CydD K16013 cydD; ATP-binding cassette, subfamily C, bacterial CydD
D R50_0375 Macrolide export ATP-binding/permease protein MacB K05685 macB; macrolide transport system ATP-binding/permease protein [EC:7.6.2.-]
D R50_1645 Metal-binding protein K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D R50_1646 membrane protein of unknown function K15496 wtpB; molybdate/tungstate transport system permease protein
D R50_2692 Glycine/betaine ABC transporter substrate-binding protein K15551 tauA; taurine transport system substrate-binding protein
D R50_2693 tauC; taurine transporter subunit; membrane component of ABC superfamily K15552 tauC; taurine transport system permease protein
D R50_1647 protein of unknown function K11084 phnT; 2-aminoethylphosphonate transport system ATP-binding protein
D R50_0418 ABC transporter permease K02050 ABC.SN.P; NitT/TauT family transport system permease protein
D R50_0416 ssuB; Aliphatic sulfonates import ATP-binding protein SsuB 2 K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein
D R50_2691 ssuB; aliphatic sulfonate ABC transporter (ATP-binding protein) K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein
D R50_0756 frcA; Fructose import ATP-binding protein FrcA K10554 frcA; fructose transport system ATP-binding protein
D R50_0758 LacI family transcriptional regulator K10439 rbsB; ribose transport system substrate-binding protein
D R50_0834 Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1) K10439 rbsB; ribose transport system substrate-binding protein
D R50_0757 ABC transporter permease K10440 rbsC; ribose transport system permease protein
D R50_0836 rbsC; ribose ABC transporter (permease) K10440 rbsC; ribose transport system permease protein
D R50_0835 rbsA; ribose ABC transporter (ATP-binding protein) K10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]
D R50_2230 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) K02037 pstC; phosphate transport system permease protein
D R50_2228 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) K02038 pstA; phosphate transport system permease protein
D R50_2227 pstBB; phosphate ABC transporter (ATP-binding protein) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D R50_1218 SBP_bac_5 domain-containing protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D R50_1216 appB; oligopeptide ABC transporter (permease) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D R50_1217 ABC transmembrane type-1 domain-containing protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D R50_1747 dppD; dipeptide ABC transporter (ATP-binding subunit) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D R50_1746 appF; oligopeptide ABC transporter (ATP-binding protein) K02032 ddpF; peptide/nickel transport system ATP-binding protein
D R50_1805 ylmA; Uncharacterized ABC transporter ATP-binding protein YlmA K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D R50_1685 Biotin transporter K03523 bioY; biotin transport system substrate-specific component
D R50_0188 Transport permease protein K09690 wzm; homopolymeric O-antigen transport system permease protein
D R50_0189 ABC transporter domain-containing protein K09691 wzt; homopolymeric O-antigen transport system ATP-binding protein [EC:7.5.2.14]
D R50_1479 ccmA; Heme ABC exporter ATP-binding protein CcmA K20490 nisF; lantibiotic transport system ATP-binding protein
D R50_1320 Nitrous oxide reductase maturation transmembrane protein NosY K19341 nosY; Cu-processing system permease protein
D R50_1321 ABC transporter-like protein K19340 nosF; Cu-processing system ATP-binding protein
D R50_1477 putative Cytochrome c-type biogenesis protein CcmC, heme lyase for CcmE K02195 ccmC; heme exporter protein C
D R50_1478 ABC transporter involved in cytochrome c biogenesis, CcmB subunit K02194 ccmB; heme exporter protein B
D R50_1851 Cell division protein FtsX K09811 ftsX; cell division transport system permease protein
D R50_1852 ftsE; cell-division signal transducer (ATP-binding protein) K09812 ftsE; cell division transport system ATP-binding protein
D R50_0478 Transport permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D R50_0677 ABC transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D R50_0777 Transport permease protein (modular protein) K01992 ABC-2.P; ABC-2 type transport system permease protein
D R50_0803 conserved membrane protein of unknown function K01992 ABC-2.P; ABC-2 type transport system permease protein
D R50_0477 ABC transporter domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D R50_0587 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D R50_0676 ABC transporter domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D R50_0778 nodI; Nod factor export ATP-binding protein I K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D R50_0802 ABC transporter domain-containing protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D R50_1427 sufC; sulfur mobilizing ABC protein, ATPase K09013 sufC; Fe-S cluster assembly ATP-binding protein
D R50_2218 naiP; Putative niacin/nicotinamide transporter NaiP K28762 niaP; MFS transporter, niacin uptake porter
D R50_0700 MFS domain-containing protein K08176 PHO84; MFS transporter, PHS family, inorganic phosphate transporter
D R50_2383 MFS transporter K08176 PHO84; MFS transporter, PHS family, inorganic phosphate transporter
D R50_1493 Major facilitator superfamily MFS_1 K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D R50_1496 Nitrate/nitrite transporter K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D R50_0841 MFS transporter K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D R50_1630 yitG; putative efflux transporter K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D R50_0302 MFS transporter K08223 fsr; MFS transporter, FSR family, fosmidomycin resistance protein
D R50_0037 Phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D R50_0038 HPr family phosphocarrier protein K02784 ptsH; phosphocarrier protein HPr
D R50_0040 putative PTS sugar transporter subunit IIA K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D R50_1894 aqpM; putative aquaporin AqpM K06188 aqpZ; aquaporin
D R50_2198 Ammonium transporter K03320 amt; ammonium transporter, Amt family
D R50_2776 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel K22044 ybiO; moderate conductance mechanosensitive channel
D R50_0498 Flagellar motor rotation protein MotA K02556 motA; chemotaxis protein MotA
D R50_0499 Flagellar motor rotation protein MotB K02557 motB; chemotaxis protein MotB
D R50_1014 conserved protein of unknown function K03284 corA; magnesium transporter
D R50_1222 conserved protein of unknown function K03284 corA; magnesium transporter
D R50_1822 crcB; Putative fluoride ion transporter CrcB K06199 crcB; fluoride exporter
D R50_1823 crcB; Putative fluoride ion transporter CrcB K06199 crcB; fluoride exporter
D R50_2122 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D R50_1741 Amino acid transporter, AAT family K11735 gabP; GABA permease
D R50_0583 Cobalt-zinc-cadmium resistance protein CzcD K16264 czcD; cobalt-zinc-cadmium efflux system protein
D R50_0999 Sodium:proton exchanger K07301 yrbG; cation:H+ antiporter
D R50_2366 Cell volume regulation protein A K11105 cvrA; potassium/hydrogen antiporter
D R50_2156 Chloride channel protein, CIC family K03281 clcA; chloride channel protein, CIC family
D R50_0268 Chromate transporter K07240 chrA; chromate transporter
D R50_2605 Sodium-dependent phosphate transporter K03324 yjbB; phosphate:Na+ symporter
D R50_0132 arsF; arsenite/antimonite/H+ antiporter K03893 arsB; arsenical pump membrane protein
D R50_2618 Stage V sporulation protein B K06409 spoVB; stage V sporulation protein B
D R50_1565 murJ; putative lipid II flippase MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D R50_0781 Iron transporter K22736 VIT; vacuolar iron transporter family protein
D R50_1116 conserved membrane protein of unknown function K22736 VIT; vacuolar iron transporter family protein
D R50_1545 Iron transporter K22736 VIT; vacuolar iron transporter family protein
D R50_0553 putative integral membrane protein K05595 marC; multiple antibiotic resistance protein
D R50_0959 spoVE; factor for spore cortex peptidoglycan synthesis (stage V sporulation) K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D R50_2234 membrane protein of unknown function K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D R50_1127 Ferrous iron transport permease EfeU K07243 FTR; high-affinity iron transporter
D R50_0920 yqjD; putative propionyl-CoA carboxylase beta chain K01604 mmdA; methylmalonyl-CoA decarboxylase subunit alpha [EC:7.2.4.3]
D R50_0922 gcdC; Glutaconyl-CoA decarboxylase subunit gamma K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
D R50_1521 DsbD domain-containing protein K06196 ccdA; cytochrome c-type biogenesis protein
D R50_1501 narG; nitrate reductase (alpha subunit) K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D R50_1500 narH; nitrate reductase (beta subunit) K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D R50_1498 narI; nitrate reductase (gamma subunit) K00374 narI; nitrate reductase gamma subunit [EC:1.7.5.1 1.7.99.-]
D R50_0840 Biotin attachment protein K03543 emrA; membrane fusion protein, multidrug efflux system
D R50_0842 Multidrug resistance protein (function not yet clear) K03543 emrA; membrane fusion protein, multidrug efflux system
D R50_0843 Ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D R50_1482 Cytochrome c heme lyase subunit CcmF K02198 ccmF; cytochrome c-type biogenesis protein CcmF
D R50_0599 conserved membrane protein of unknown function K00389 yidH; inner membrane protein YidH
C 02044 Secretion system [BR:hfv02044]
D R50_0592 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D R50_0377 conserved protein of unknown function K02282 cpaE; pilus assembly protein CpaE
D R50_0593 Pilus assembly protein CpaE K02282 cpaE; pilus assembly protein CpaE
D R50_0594 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1708 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1954 T2SP_E domain-containing protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1966 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_0381 Flp pilus assembly protein TadB K12510 tadB; tight adherence protein B
D R50_0595 Flp pilus assembly protein TadB K12510 tadB; tight adherence protein B
D R50_0379 conserved protein of unknown function K12513 tadE; tight adherence protein E
D R50_0591 conserved protein of unknown function K02651 flp; pilus assembly protein Flp/PilA
D R50_0975 YggT family protein K02221 yggT; YggT family protein
D R50_0520 flhA; component of the flagellar export machinery K02400 flhA; flagellar biosynthesis protein FlhA
D R50_0519 Flagellar biosynthesis protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB
D R50_0503 Flagellar M-ring protein K02409 fliF; flagellar M-ring protein FliF
D R50_0506 fliI; flagellar-specific ATPase subunit of export apparatus K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]
D R50_0438 Flagellar motor switch protein FliM K02417 fliN; flagellar motor switch protein FliN
D R50_0531 FliMN_C domain-containing protein K02417 fliN; flagellar motor switch protein FliN
D R50_0515 Flagellar protein (modular protein) K02418 fliO; flagellar protein FliO/FliZ
D R50_0516 fliP; component of the flagellar export machinery K02419 fliP; flagellar biosynthesis protein FliP
D R50_0517 fliQ; flagellar biosynthesis protein K02420 fliQ; flagellar biosynthesis protein FliQ
D R50_0518 Flagellar biosynthesis protein FliR K02421 fliR; flagellar biosynthesis protein FliR
D R50_0650 secA; translocase binding subunit (ATPase) K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D R50_2468 Preprotein translocase subunit SecE (TC 3.A.5.1.1) K03073 secE; preprotein translocase subunit SecE
D R50_2217 secG; preprotein translocase subunit K03075 secG; preprotein translocase subunit SecG
D R50_2431 secY; preprotein translocase subunit K03076 secY; preprotein translocase subunit SecY
D R50_1586 ffh; signal recognition particle-like (SRP) GTPase K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D R50_1588 ftsY; signal recognition particle (docking protein) K03110 ftsY; fused signal recognition particle receptor
D R50_0918 protein of unknown function K03210 yajC; preprotein translocase subunit YajC
D R50_2786 membrane protein of unknown function K03217 yidC; YidC/Oxa1 family membrane protein insertase
D R50_0746 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_1063 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_2650 Twin-arginine translocation protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D R50_0829 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:hfv02042]
D R50_2122 HlyC/CorC family transporter K03699 tlyC; magnesium and cobalt exporter, CNNM family
D R50_0568 Phosphoesterase K01114 plc; phospholipase C [EC:3.1.4.3]
C 02022 Two-component system [BR:hfv02022]
D R50_2231 PAS domain-containing sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D R50_2575 putative Phosphate regulon transcriptional regulatory protein PhoB K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
D R50_1246 Osmosensitive K+ channel histidine kinase KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D R50_1245 kdpE; DNA-binding response regulator in two-component regulatory system with KdpD K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D R50_2206 mprA; Response regulator MprA K11521 manR; two-component system, OmpR family, manganese sensing response regulator
D R50_1509 putative Histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D R50_0718 mtrA; DNA-binding response regulator MtrA K02483 K02483; two-component system, OmpR family, response regulator
D R50_2232 phoP; two-component response regulator K02483 K02483; two-component system, OmpR family, response regulator
D R50_0780 putative Sensor histidine kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
D R50_0779 Two component transcriptional regulator, LuxR family K07693 desR; two-component system, NarL family, response regulator DesR
D R50_1158 spo0A; response regulator, phosphorylated in response to complex YlbF/YmcA/YaaT K07699 spo0A; two-component system, response regulator, stage 0 sporulation protein A
D R50_2252 putative Histidine kinase K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
D R50_2253 Two component transcriptional regulator, LytTR family K07705 lytT; two-component system, LytTR family, response regulator LytT
D R50_0386 Signal transduction histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D R50_0441 cheY; regulator of chemotaxis and motility K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D R50_0563 cheB; Protein-glutamate methylesterase/protein-glutamine glutaminase 1 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D R50_0462 putative transcriptional regulatory protein pdtaR K22010 pdtaR; two-component system, response regulator PdtaR
C 02035 Bacterial motility proteins [BR:hfv02035]
D R50_0386 Signal transduction histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D R50_0385 CheW-like domain-containing protein K03408 cheW; purine-binding chemotaxis protein CheW
D R50_0440 Chemotaxis protein CheC --inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D R50_0562 CheR-type methyltransferase domain-containing protein K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D R50_0563 cheB; Protein-glutamate methylesterase/protein-glutamine glutaminase 1 K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D R50_0441 cheY; regulator of chemotaxis and motility K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D R50_0384 protein of unknown function K06595 hemAT; heam-based aerotactic trancducer
D R50_0506 fliI; flagellar-specific ATPase subunit of export apparatus K02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]
D R50_0515 Flagellar protein (modular protein) K02418 fliO; flagellar protein FliO/FliZ
D R50_0516 fliP; component of the flagellar export machinery K02419 fliP; flagellar biosynthesis protein FliP
D R50_0517 fliQ; flagellar biosynthesis protein K02420 fliQ; flagellar biosynthesis protein FliQ
D R50_0518 Flagellar biosynthesis protein FliR K02421 fliR; flagellar biosynthesis protein FliR
D R50_0520 flhA; component of the flagellar export machinery K02400 flhA; flagellar biosynthesis protein FlhA
D R50_0519 Flagellar biosynthesis protein FlhB K02401 flhB; flagellar biosynthesis protein FlhB
D R50_0504 fliG; flagellar motor switching and energizing component K02410 fliG; flagellar motor switch protein FliG
D R50_0530 Flagellar motor switch protein FliM K02416 fliM; flagellar motor switch protein FliM
D R50_0438 Flagellar motor switch protein FliM K02417 fliN; flagellar motor switch protein FliN
D R50_0531 FliMN_C domain-containing protein K02417 fliN; flagellar motor switch protein FliN
D R50_0503 Flagellar M-ring protein K02409 fliF; flagellar M-ring protein FliF
D R50_0502 Flagellar hook-basal body complex protein FliE K02408 fliE; flagellar hook-basal body complex protein FliE
D R50_0500 Flagellar basal body rod protein FlgB K02387 flgB; flagellar basal-body rod protein FlgB
D R50_0501 flgC; flagellar component of cell-proximal portion of basal-body rod K02388 flgC; flagellar basal-body rod protein FlgC
D R50_0511 Flagellar hook capping protein K02389 flgD; flagellar basal-body rod modification protein FlgD
D R50_0523 Flagellar basal-body rod protein flgG K02391 flgF; flagellar basal-body rod protein FlgF
D R50_0524 Flagellar basal body protein K02392 flgG; flagellar basal-body rod protein FlgG
D R50_0513 Flagellar hook protein flgE K02390 flgE; flagellar hook protein FlgE
D R50_0535 Flagellar hook-associated protein flgK K02396 flgK; flagellar hook-associated protein 1
D R50_0534 Flagellar hook-associated protein flgL K02397 flgL; flagellar hook-associated protein 3 FlgL
D R50_0526 Flagellin K02406 fliC; flagellin
D R50_0527 Flagellar hook-associated protein fliD K02407 fliD; flagellar hook-associated protein 2
D R50_0498 Flagellar motor rotation protein MotA K02556 motA; chemotaxis protein MotA
D R50_0499 Flagellar motor rotation protein MotB K02557 motB; chemotaxis protein MotB
D R50_0533 fliW; Flagellar assembly factor FliW K13626 fliW; flagellar assembly factor FliW
D R50_0521 Flagellar biosynthesis protein FlhF K02404 flhF; flagellar biosynthesis protein FlhF
D R50_0522 Site-determining protein K04562 flhG; flagellar biosynthesis protein FlhG
D R50_0591 conserved protein of unknown function K02651 flp; pilus assembly protein Flp/PilA
D R50_0592 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D R50_0377 conserved protein of unknown function K02282 cpaE; pilus assembly protein CpaE
D R50_0593 Pilus assembly protein CpaE K02282 cpaE; pilus assembly protein CpaE
D R50_0594 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1708 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1954 T2SP_E domain-containing protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D R50_1966 Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:hfv04812]
D R50_2185 mreB; cell-shape determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D R50_1993 ALP_N domain-containing protein K18640 parM; plasmid segregation protein ParM
D R50_0966 ftsZ; cell-division initiation protein K03531 ftsZ; cell division protein FtsZ
D R50_0965 ftsA; Cell division protein FtsA K03590 ftsA; cell division protein FtsA
D R50_0609 minC; putative septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D R50_2182 minC; Septum site-determining protein MinC K03610 minC; septum site-determining protein MinC
D R50_2181 minD; ATPase activator of MinC K03609 minD; septum site-determining protein MinD
D R50_2180 minE; Cell division topological specificity factor K03608 minE; cell division topological specificity factor
D R50_2784 parA; chromosome partitioning protein; transcriptional regulator K03496 parA; chromosome partitioning protein
D R50_2783 parB; site-specific DNA-binding protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:hfv04147]
D R50_2220 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D R50_2224 gapA; glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D R50_2223 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D R50_0996 pyk; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D R50_1363 putative Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D R50_0181 ahpA; biofilm-specific peroxidase; 2-cys peroxiredoxin K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D R50_1798 Peroxiredoxin 2 K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D R50_1768 groEL; chaperonin large subunit K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D R50_1655 dnaK; molecular chaperone, ATP-dependent K04043 dnaK; molecular chaperone DnaK
D R50_1773 guaB; inosine-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D R50_2453 tufA; elongation factor Tu K02358 tuf; elongation factor Tu
D R50_2134 Uncharacterized HIT-like protein aq_141 K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D R50_1570 Long-chain fatty acid--CoA ligase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D R50_1229 S-inosyl-L-homocysteine hydrolase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D R50_2430 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D R50_2299 argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D R50_2300 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D R50_0428 Dihydropyrimidinase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D R50_1125 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_2306 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D R50_0856 hemB; delta-aminolevulinic acid dehydratase (porphobilinogen synthase) K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D R50_1388 putative 4a-hydroxytetrahydrobiopterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D R50_0472 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D R50_1753 purH; fused phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D R50_0569 Dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_2760 lpdV; branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase) K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D R50_1177 Electron transfer flavoprotein, alpha subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D R50_0450 zwf; Glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D R50_1121 zwf; glucose-6-phosphate 1-dehydrogenase K00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]
D R50_2222 tpiA; triose phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:hfv02048]
D R50_0074 cas1; CRISPR-associated endonuclease Cas1 2 K15342 cas1; CRISP-associated protein Cas1
D R50_0072 CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D R50_0073 CRISPR-associated RecB family exonuclease Cas4a K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D R50_2566 putative DNA helicase K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D R50_0068 CRISPR-associated endoribonuclease K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D R50_0070 CRISPR-associated protein Csd2 K19115 csh2; CRISPR-associated protein Csh2
D R50_0071 conserved protein of unknown function K19116 cas5h; CRISPR-associated protein Cas5h
D R50_0359 cmr; Type III-B CRISPR module RAMP protein Cmr1 K07061 cmr1; CRISPR-associated protein Cmr1
D R50_0360 CRISPR-associated protein, Crm2 family K19076 cmr2; CRISPR-associated protein Cmr2
D R50_0361 conserved protein of unknown function K09127 cmr3; CRISPR-associated protein Cmr3
D R50_0362 Type III-B CRISPR module RAMP protein Cmr4 K09000 cmr4; CRISPR-associated protein Cmr4
D R50_0363 Type III-B CRISPR module-associated protein Cmr5 K19141 cmr5; CRISPR-associated protein Cmr5
D R50_0436 mjaIIIM; Modification methylase MjaIII K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2006 protein of unknown function K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2029 DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D R50_2477 N6_N4_Mtase domain-containing protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
D R50_1918 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2019 Cytosine-specific methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D R50_2020 cfr9IM; Modification methylase Cfr9I K00590 E2.1.1.113; site-specific DNA-methyltransferase (cytosine-N4-specific) [EC:2.1.1.113]
D R50_1790 ndoA; endoribonuclease toxin K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D R50_1791 RHH_1 domain-containing protein K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI
D R50_0966 ftsZ; cell-division initiation protein K03531 ftsZ; cell division protein FtsZ
D R50_2185 mreB; cell-shape determining protein K03569 mreB; rod shape-determining protein MreB and related proteins
D R50_2670 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D R50_0267 conserved protein of unknown function K28186 hepT; HepT family RNase toxin
D R50_0266 Nucleotidyltransferase domain-containing protein K28187 mntA; MntA family adenylyltransferase antitoxin
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hfv00537]
D R50_1363 putative Membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:hfv03100]
D R50_TRNA10 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D R50_TRNA15 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D R50_TRNA23 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D R50_TRNA2 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA4 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA40 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA42 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D R50_TRNA31 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D R50_TRNA18 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D R50_TRNA21 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D R50_TRNA16 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D R50_TRNA51 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D R50_TRNA11 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D R50_TRNA50 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D R50_TRNA14 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA20 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA37 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA55 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D R50_TRNA39 tRNA-His K14226 tRNA-His; tRNA His
D R50_TRNA29 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA30 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA47 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA49 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D R50_TRNA24 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA27 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA28 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA38 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA48 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D R50_TRNA12 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D R50_TRNA6 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D R50_TRNA32 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA44 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA7 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA8 tRNA-Met K14230 tRNA-Met; tRNA Met
D R50_TRNA19 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D R50_TRNA25 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA26 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA35 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA41 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D R50_TRNA3 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D R50_TRNA52 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D R50_TRNA53 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D R50_TRNA43 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D R50_TRNA46 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D R50_TRNA54 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D R50_TRNA13 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D R50_TRNA45 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D R50_TRNA17 tRNA-Val K14237 tRNA-Val; tRNA Val
D R50_TRNA22 tRNA-Val K14237 tRNA-Val; tRNA Val
D R50_TRNA33 tRNA-Val K14237 tRNA-Val; tRNA Val
D R50_TRNA9 tRNA-Sec K14238 tRNA-Sec; tRNA Sec
D R50_RRNA2 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA4 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA6 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_RRNA8 ribosomal RNA 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D R50_MISCRNA171 RNaseP_bact_a K01978 rnpB; RNase P catalytic RNA component
D R50_MISCRNA91 6S K28358 ssrS; RNA polymerase binding 6S RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D R50_0690 Pyr_redox_2 domain-containing protein K28385 hdrA; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit A [EC:1.8.4.17]
D R50_1171 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K28385 hdrA; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit A [EC:1.8.4.17]
D R50_0689 Heterodisulfide reductase subunit B K28386 hdrB; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit B [EC:1.8.4.17]
D R50_0693 CoB--CoM heterodisulfide reductase subunit B K28386 hdrB; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit B [EC:1.8.4.17]
D R50_1170 CCG domain-containing protein K28386 hdrB; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit B [EC:1.8.4.17]
D R50_0688 CoB--CoM heterodisulfide reductase subunit C K28387 hdrC; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit C [EC:1.8.4.17]
D R50_0692 Heterodisulfide reductase subunit C K28387 hdrC; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit C [EC:1.8.4.17]
D R50_1169 CoB--CoM heterodisulfide reductase subunit C K28387 hdrC; sulfur-oxidizing heterodisulfide reductase-like enzyme system (type I) subunit C [EC:1.8.4.17]
D R50_2729 bcp; peroxiredoxin with versatile activity K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D R50_0705 tpx; thiol peroxidase (lipid hydroperoxide reductase) K11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D R50_1065 hynB; Hydrogenase large subunit K05922 hydB; quinone-reactive Ni/Fe-hydrogenase large subunit [EC:1.12.5.1]
D R50_1064 hynA; Hydrogenase small subunit K05927 hydA; quinone-reactive Ni/Fe-hydrogenase small subunit [EC:1.12.5.1]
D R50_1913 conserved protein of unknown function K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D R50_0139 merA; Mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D R50_0699 merA; Mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D R50_1550 Ferredoxin--NADP reductase 2 K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D R50_0179 Ribonucleotide reductase of class III (anaerobic), activating protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D R50_0029 Hydrogenase-4 component F K12141 hyfF; hydrogenase-4 component F [EC:1.-.-.-]
D R50_2571 modD; Putative pyrophosphorylase ModD K03813 modD; molybdenum transport protein [EC:2.4.2.-]
D R50_2287 lgt; Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D R50_2117 ppsR; bifunctional ADP-dependent kinase-Pi-dependent pyrophosphorylase / positive regulator of gluconeogenesis K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]
D R50_2491 disA; diadenylate cyclase; DNA integrity scanning protein; cell cycle checkpoint DNA scanning protein K07067 disA; diadenylate cyclase [EC:2.7.7.85]
D R50_1818 cdaA; diadenylate cyclase K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D R50_1182 spoIIAB; anti-sigma factor (antagonist of sigma(F)) and serine kinase K06379 spoIIAB; stage II sporulation protein AB (anti-sigma F factor) [EC:2.7.11.1]
D R50_2496 mcsB; protein arginine kinase K19405 mcsB; protein arginine kinase [EC:2.7.14.1]
D R50_2551 O-acetyl-ADP-ribose deacetylase (Regulator of RNase III), contains Macro domain K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D R50_2609 Thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D R50_2592 Stage II sporulation serine phosphatase for sigma-F activation (SpoIIE) K06382 spoIIE; stage II sporulation protein E [EC:3.1.3.16]
D R50_1425 yqeG; phosphatase (active on GMP and Glc-6-P) K07015 yqeG; putative phosphatase [EC:3.1.3.-]
D R50_2125 Membrane protein containing HD superfamily hydrolase domain, YQFF ortholog K07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-]
D R50_1338 Putative deoxyribonuclease YcfH K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D R50_2637 dayD; D-amino acyl-tRNA deacylase K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D R50_0429 dag; N-acyl-D-glutamate deacylase K06015 E3.5.1.81; N-acyl-D-amino-acid deacylase [EC:3.5.1.81]
D R50_2248 def; Peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D R50_1272 NodB homology domain-containing protein K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D R50_1625 Chitooligosaccharide deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D R50_0425 8-oxoguanine deaminase K18456 E3.5.4.32; 8-oxoguanine deaminase [EC:3.5.4.32]
D R50_2480 yeaC; putative MoxR-like ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D R50_0627 ywle; Protein-arginine-phosphatase K20201 ywlE; protein arginine phosphatase [EC:3.9.1.2]
D R50_1793 nnr; ADP-dependent (S)-NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D R50_2381 putative Tetraprenyl-beta-curcumene synthase K16188 ytpB; tetraprenyl-beta-curcumene synthase [EC:4.2.3.130]
D R50_1905 dpaL; Diaminopropionate ammonia-lyase K01751 E4.3.1.15; diaminopropionate ammonia-lyase [EC:4.3.1.15]
D R50_1019 tcaB; P-type calcium transport ATPase (sporulation) K01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D R50_1908 fdhD; Sulfur carrier protein FdhD K02379 fdhD; FdhD protein
D R50_1430 sufU; iron-sulfur cluster assembly sulfur-transfer protein [Zn(2+)-dependent] K04488 iscU; nitrogen fixation protein NifU and related proteins
D R50_0454 nifX; Putative nitrogenase FeMo-cofactor carrier protein K02596 nifX; nitrogen fixation protein NifX
D R50_0452 nifZ; Nitrogenase maturation protein K02597 nifZ; nitrogen fixation protein NifZ
D R50_0464 nifB; FeMo cofactor biosynthesis protein K02585 nifB; nitrogen fixation protein NifB
D R50_0455 nifN; Nitrogenase iron-molybdenum cofactor biosynthesis protein K02592 nifN; nitrogenase molybdenum-iron protein NifN
D R50_0456 nifE; Nitrogenase iron-molybdenum cofactor biosynthesis protein K02587 nifE; nitrogenase molybdenum-cofactor synthesis protein NifE
D R50_1069 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein K02573 napG; ferredoxin-type protein NapG
D R50_1176 Electron transfer flavoprotein, beta subunit K03521 fixA; electron transfer flavoprotein beta subunit
D R50_1184 putative Dodecin K09165 K09165; dodecin
C 99983 Lipid metabolism
D R50_1613 conserved protein of unknown function K25232 fakB; fatty acid kinase fatty acid binding subunit
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D R50_0973 Pyridoxal phosphate homeostasis protein K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D R50_0646 cspD; cold-shock protein, molecular chaperone, RNA-helicase co-factor K03704 cspA; cold shock protein
D R50_1024 Putative regulatory protein Teth39_1325 K09777 remA; extracellular matrix regulatory protein A
D R50_0006 conserved protein of unknown function K24648 remB; extracellular matrix regulatory protein B
C 99974 Translation
D R50_2611 yabR; putative RNA degradation protein; polyribonucleotide nucleotidyltransferase or phosphorylase K07571 K07571; S1 RNA binding domain protein
C 99975 Protein processing
D R50_2497 Nucleotide excision repair protein, with UvrB/UvrC motif K19411 mcsA; protein arginine kinase activator
D R50_2201 tig; Trigger factor K03545 tig; trigger factor
D R50_2257 Urease accessory protein UreF K03188 ureF; urease accessory protein
D R50_2256 ureG; Urease accessory protein UreG 2 K03189 ureG; urease accessory protein
D R50_2255 UreD; Putative Urease accessory protein K03190 ureD; urease accessory protein
D R50_2212 smpB; tmRNA-binding protein K03664 smpB; SsrA-binding protein
D R50_1061 hypC; HypC/HybG/HupF family hydrogenase formation chaperone K04653 hypC; hydrogenase expression/formation protein HypC
D R50_1068 HypC; Hydrogenase accessory protein K04653 hypC; hydrogenase expression/formation protein HypC
D R50_2280 hypC; Hydrogenase accessory protein K04653 hypC; hydrogenase expression/formation protein HypC
D R50_2279 hypD; protein required for maturation of hydrogenases K04654 hypD; hydrogenase expression/formation protein HypD
D R50_0818 putative Thiamine-phosphate kinase K04655 hypE; hydrogenase expression/formation protein HypE
D R50_1062 hypE; Carbamoyltransferase, hydrogen maturation protein K04655 hypE; hydrogenase expression/formation protein HypE
D R50_2278 hypE; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein K04655 hypE; hydrogenase expression/formation protein HypE
D R50_1081 hypF; Carbamoyltransferase HypF2 K04656 hypF; hydrogenase maturation protein HypF
D R50_2326 hypF; Carbamoyltransferase HypF2 K04656 hypF; hydrogenase maturation protein HypF
D R50_2294 OsmC/Ohr family protein K07397 yhfA; putative redox protein
D R50_0421 XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase) K07402 xdhC; xanthine dehydrogenase accessory factor
C 99976 Replication and repair
D R50_0771 yneB; Resolvase YneB K07450 K07450; putative resolvase
D R50_0927 protein of unknown function K07450 K07450; putative resolvase
D R50_1109 yneB; Resolvase YneB K07450 K07450; putative resolvase
D R50_1985 protein of unknown function K07450 K07450; putative resolvase
D R50_2004 transposase K07450 K07450; putative resolvase
D R50_2556 protein of unknown function K07450 K07450; putative resolvase
D R50_2186 ysxA; conserved nucleotide-related metabolism protein K03630 radC; DNA repair protein RadC
D R50_0060 DNA recombination protein RmuC K09760 rmuC; DNA recombination protein RmuC
D R50_1004 nth; Endonuclease III K07457 K07457; endonuclease III related protein
D R50_2642 GIY-YIG domain-containing protein K07461 K07461; putative endonuclease
D R50_1546 Toprim domain-containing protein K07476 yusF; toprim domain protein
D R50_1460 AAA domain-containing protein K07478 ycaJ; putative ATPase
D R50_2092 3'-5' exonuclease K07501 K07501; 3'-5' exonuclease
D R50_2382 Polysaccharide biosynthesis protein WlaX K07501 K07501; 3'-5' exonuclease
D R50_1990 transposase K07491 rayT; REP-associated tyrosine transposase
D R50_2010 transposase K07491 rayT; REP-associated tyrosine transposase
D R50_0195 transposase K07493 K07493; putative transposase
D R50_2313 transposase K07493 K07493; putative transposase
D R50_0772 transposase K07496 K07496; putative transposase
D R50_1106 protein of unknown function K07496 K07496; putative transposase
D R50_1219 transposase K07496 K07496; putative transposase
D R50_1989 transposase K07496 K07496; putative transposase
D R50_2005 transposase K07496 K07496; putative transposase
C 99979 Viral proteins
C 99998 Others
D R50_2662 PspA/IM30 family protein K03969 pspA; phage shock protein A
D R50_2675 ebfC; nucleoid associated protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D R50_2236 Amino acid permease K03293 TC.AAT; amino acid transporter, AAT family
D R50_0447 mctP; Monocarboxylate transport permease protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D R50_2377 conserved membrane protein of unknown function K03307 TC.SSS; solute:Na+ symporter, SSS family
D R50_0430 Allantoin permease K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
D R50_1869 Allantoin permease K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
C 99978 Cell growth
D R50_1694 putative 5-oxoprolinase subunit C K06350 kipA; antagonist of KipI
D R50_1202 spmA; spore maturation protein K06373 spmA; spore maturation protein A
D R50_1203 spmB; spore maturation protein K06374 spmB; spore maturation protein B
D R50_1181 anti-sigma F factor antagonist (spoIIAA-2); anti sigma b factor antagonist RsbV K06378 spoIIAA; stage II sporulation protein AA (anti-sigma F factor antagonist)
D R50_1163 Stage II sporulation protein M (SpoIIM) K06384 spoIIM; stage II sporulation protein M
D R50_1410 Stage III sporulation protein AA K06390 spoIIIAA; stage III sporulation protein AA
D R50_1409 protein of unknown function K06391 spoIIIAB; stage III sporulation protein AB
D R50_1408 spoIIIAC; Stage III sporulation protein AC K06392 spoIIIAC; stage III sporulation protein AC
D R50_1407 Stage III sporulation protein AD K06393 spoIIIAD; stage III sporulation protein AD
D R50_1406 Stage III sporulation protein AE K06394 spoIIIAE; stage III sporulation protein AE
D R50_1403 protein of unknown function K06396 spoIIIAG; stage III sporulation protein AG
D R50_1402 conserved protein of unknown function K06397 spoIIIAH; stage III sporulation protein AH
D R50_1215 spoIVA; morphogenetic stage IV sporulation protein K06398 spoIVA; stage IV sporulation protein A
D R50_1185 spoVAC; mechanosensitive channel; stage V sporulation protein AC K06405 spoVAC; stage V sporulation protein AC
D R50_1186 spoVAD; stage V sporulation protein AD (uptake of pyridine-2,6-dicarboxylic acid) K06406 spoVAD; stage V sporulation protein AD
D R50_1187 spoVAEB; spore germinant protein K06407 spoVAE; stage V sporulation protein AE
D R50_1188 Stage V sporulation protein AE (SpoVAE) K06407 spoVAE; stage V sporulation protein AE
D R50_1525 Hydroxyacid dehydrogenase K06410 spoVFA; dipicolinate synthase subunit A
D R50_1524 spoVFB; spore dipicolinate synthase subunit B K06411 spoVFB; dipicolinate synthase subunit B
D R50_2627 spoVG; regulator required for spore cortex synthesis (stage V sporulation) K06412 spoVG; stage V sporulation protein G
D R50_1352 spoVK; mother cell sporulation ATPase K06413 spoVK; stage V sporulation protein K
D R50_1535 putative Stage V sporulation protein R K06415 spoVR; stage V sporulation protein R
D R50_1590 spoVS; regulator required for dehydratation of the spore core and assembly of the coat (stage V sporulation) K06416 spoVS; stage V sporulation protein S
D R50_1239 Small acid-soluble spore protein K06418 sspA_B_C_D; small acid-soluble spore protein A/B/C/D
D R50_1643 Small, acid-soluble spore protein alpha K06418 sspA_B_C_D; small acid-soluble spore protein A/B/C/D
D R50_1135 protein of unknown function K06423 sspF; small acid-soluble spore protein F
D R50_2127 putative stage IV sporulation protein K06438 yqfD; similar to stage IV sporulation protein
D R50_2147 Spore germination protein GerKA K06295 gerKA; spore germination protein KA
D R50_0888 putative Spore gernimation protein K06297 gerKC; spore germination protein KC
D R50_2148 Spore germination protein GerKC K06308 yfkR; spore germination protein
D R50_0889 Spore germination protein GerKA K06310 yndD; spore germination protein
C 99993 Cell motility
C 99995 Signaling proteins
D R50_1008 bipA; ribosome-associated GTPase K06207 typA; GTP-binding protein
D R50_2126 phoH; phosphate starvation-induced protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
D R50_1534 prkA; serine protein kinase (involved in sporulation) K07180 prkA; serine protein kinase
C 99992 Structural proteins
D R50_0319 protein of unknown function K07273 acm; lysozyme
D R50_0019 Biotin_lipoyl_2 domain-containing protein K02005 ABC.CD.TX; HlyD family secretion protein
D R50_1483 Cytochrome C biogenesis protein CcmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE
C 99994 Others
D R50_2226 phoU; Phosphate-specific transport system accessory protein PhoU homolog K02039 phoU; phosphate transport system protein
D R50_1322 Nitrous oxide reductase maturation protein NosD K07218 nosD; nitrous oxidase accessory protein
D R50_1319 conserved protein of unknown function K19342 nosL; copper chaperone NosL
B
B 09194 Poorly characterized
C 99996 General function prediction only
D R50_0713 csaA; molecular chaperone for secreting proteins K06878 K06878; tRNA-binding protein
D R50_0402 SSD domain-containing protein K06994 K06994; putative drug exporter of the RND superfamily
D R50_1302 SSD domain-containing protein K06994 K06994; putative drug exporter of the RND superfamily
D R50_1621 Serine protease K07001 K07001; NTE family protein
D R50_2142 Putative hydrolase of the HAD superfamily K07025 K07025; putative hydrolase of the HAD superfamily
D R50_2668 Iron-sulfur cluster insertion protein ErpA K15724 erpA; iron-sulfur cluster insertion protein
D R50_0055 putative Fe-S cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D R50_1431 sufB; FeS cluster formation scaffold protein K09014 sufB; Fe-S cluster assembly protein SufB
D R50_1428 Iron-sulfur cluster assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD
D R50_1956 Inner membrane protein K07038 K07038; inner membrane protein
D R50_1289 Ribonuclease BN K07058 K07058; membrane protein
D R50_0600 conserved membrane protein of unknown function K02862 ctaG; putative membrane protein
D R50_2161 Cytochrome c oxidase assembly protein K02862 ctaG; putative membrane protein
D R50_1902 conserved membrane protein of unknown function K01421 yhgE; putative membrane protein
D R50_1463 conserved membrane protein of unknown function K08972 K08972; putative membrane protein
D R50_1634 conserved membrane protein of unknown function K08976 K08976; putative membrane protein
D R50_0882 conserved membrane protein of unknown function K08980 K08980; putative membrane protein
D R50_0716 protein of unknown function K08982 K08982; putative membrane protein
D R50_2329 SHOCT domain-containing protein K08982 K08982; putative membrane protein
D R50_2573 protein of unknown function K08982 K08982; putative membrane protein
C 99997 Function unknown
D R50_0712 Deoxyguanosinetriphosphate triphosphohydrolase K06885 K06885; uncharacterized protein
D R50_2165 Thymidylate kinase K06888 K06888; uncharacterized protein
D R50_0151 putative membrane transporter protein K07090 K07090; uncharacterized protein
D R50_0261 putative membrane transporter protein K07090 K07090; uncharacterized protein
D R50_0442 putative membrane transporter protein K07090 K07090; uncharacterized protein
D R50_0785 putative membrane transporter protein K07090 K07090; uncharacterized protein
D R50_0791 putative membrane transporter protein K07090 K07090; uncharacterized protein
D R50_1284 putative membrane transporter protein PD_1894 K07090 K07090; uncharacterized protein
D R50_1504 putative membrane transporter protein K07090 K07090; uncharacterized protein
D R50_0685 Sulfur reduction protein DsrE K07092 K07092; uncharacterized protein
D R50_0687 DrsE domain-containing protein K07092 K07092; uncharacterized protein
D R50_1105 DrsE domain-containing protein K07092 K07092; uncharacterized protein
D R50_1175 Sulfur reduction protein DsrE K07092 K07092; uncharacterized protein
D R50_2263 Metallophosphoesterase K07096 K07096; uncharacterized protein
D R50_1299 DHHA1 domain-containing protein K07097 K07097; uncharacterized protein
D R50_1227 Metallophosphoesterase K07098 K07098; uncharacterized protein
D R50_1358 putative Transcription repressor NadR K07105 K07105; uncharacterized protein
D R50_0800 Sulf_transp domain-containing protein K07112 K07112; uncharacterized protein
D R50_2782 conserved membrane protein of unknown function K07150 K07150; uncharacterized protein
D R50_1378 Peptidase S16 K07157 K07157; uncharacterized protein
D R50_2787 ytjA; membrane protein insertion efficiency factor K08998 K08998; uncharacterized protein
D R50_1762 conserved protein of unknown function K09003 K09003; uncharacterized protein
D R50_1703 DrsE domain-containing protein K09004 K09004; uncharacterized protein
D R50_1725 DrsE domain-containing protein K09004 K09004; uncharacterized protein
D R50_0598 protein of unknown function K09005 K09005; uncharacterized protein
D R50_2132 conserved protein of unknown function K09117 K09117; uncharacterized protein
D R50_1824 conserved protein of unknown function K09137 K09137; uncharacterized protein
D R50_0825 carbon monoxide dehydrogenase G protein K09386 K09386; uncharacterized protein
D R50_0276 protein of unknown function K09700 K09700; uncharacterized protein
D R50_1154 Divergent PAP2 family protein K09775 K09775; uncharacterized protein
D R50_2634 conserved protein of unknown function K09776 K09776; uncharacterized protein
D R50_1536 conserved protein of unknown function K09786 K09786; uncharacterized protein
D R50_1587 conserved protein of unknown function K09787 K09787; uncharacterized protein
D R50_2162 Sulfite exporter TauE/SafE family protein K09792 K09792; uncharacterized protein
D R50_1601 conserved protein of unknown function K09822 K09822; uncharacterized protein
D R50_1013 conserved membrane protein of unknown function K05739 seaA; uncharacterized protein
D R50_2173 protein of unknown function K07584 ysxB; uncharacterized protein
D R50_1264 conserved exported protein of unknown function K07742 ylxR; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: January 1, 2026