+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Hydrogenobaculum sp. HO</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    HydHO_1173 CRISPR-associated protein, Cas1 family	K15342 cas1; CRISP-associated protein Cas1 
C    HydHO_0402 CRISPR-associated protein Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    HydHO_1174 CRISPR-associated protein, Cas2 family	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      HydHO_1171 CRISPR-associated helicase, Cas3 family	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
D      HydHO_0669 CRISPR-associated helicase Cas3	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
D      HydHO_0666 hypothetical protein	K19088 cst1; CRISPR-associated protein Cst1 
D      HydHO_0667 CRISPR-associated autoregulator, Cst2 family	K19075 cst2; CRISPR-associated protein Cst2 
D      HydHO_1169 CRISPR-associated autoregulator, Cst2 family	K19075 cst2; CRISPR-associated protein Cst2 
D      HydHO_0401 CRISPR-associated protein Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_1172 CRISPR-associated exonuclease, Cas4 family	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_1170 CRISPR-associated protein Cas5 family	K19090 cas5t; CRISPR-associated protein Cas5t 
D      HydHO_0668 CRISPR-associated protein Cas5	K19090 cas5t; CRISPR-associated protein Cas5t 
D      HydHO_0665 CRISPR-associated protein Cas6	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] 
C    Subtype I-B factors
D      HydHO_0401 CRISPR-associated protein Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_1172 CRISPR-associated exonuclease, Cas4 family	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
C    Subtype I-C factors
D      HydHO_0401 CRISPR-associated protein Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_1172 CRISPR-associated exonuclease, Cas4 family	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
C    Subtype I-D factors
D      HydHO_0401 CRISPR-associated protein Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_1172 CRISPR-associated exonuclease, Cas4 family	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_0665 CRISPR-associated protein Cas6	K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-] 
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
D      HydHO_0401 CRISPR-associated protein Cas4	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
D      HydHO_1172 CRISPR-associated exonuclease, Cas4 family	K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1] 
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    HydHO_0110 type I site-specific deoxyribonuclease, HsdR family	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    HydHO_0108 restriction modification system DNA specificity domain containing protein	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    HydHO_0106 type I restriction-modification system, M subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
D      HydHO_1288 HipA N-terminal domain protein	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
D      HydHO_1287 helix-turn-helix protein	K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB 
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      HydHO_0156 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      HydHO_0358 cell shape determining protein, MreB/Mrl family	K03569 mreB; rod shape-determining protein MreB and related proteins 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    HydHO_1328 Cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023