+D GENES KO
#
KEGG Orthology (KO) - Halorubrum lacusprofundi
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:hla00010]
D Hlac_0043 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D Hlac_2287 phosphoglucose isomerase (PGI) K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Hlac_2458 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D Hlac_2459 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D Hlac_1274 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Hlac_0683 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Hlac_2371 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Hlac_1672 glyceraldehyde-3-phosphate dehydrogenase, type II K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D Hlac_2372 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Hlac_1851 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Hlac_1825 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Hlac_0562 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Hlac_0592 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Hlac_0731 dehydrogenase E1 component K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0139 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0140 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Hlac_0141 catalytic domain of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Hlac_0928 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Hlac_0927 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Hlac_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Hlac_1808 Alcohol dehydrogenase GroES domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3048 Alcohol dehydrogenase zinc-binding domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0317 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_2236 phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00020 Citrate cycle (TCA cycle) [PATH:hla00020]
D Hlac_0723 2-methylcitrate synthase/citrate synthase II K01647 CS; citrate synthase [EC:2.3.3.1]
D Hlac_0098 aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Hlac_3040 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Hlac_2330 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0928 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Hlac_0927 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Hlac_2208 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Hlac_2207 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Hlac_2589 acetyl-CoA hydrolase/transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D Hlac_1990 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Hlac_1989 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Hlac_1987 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Hlac_1988 succinate dehydrogenase, subunit D (membrane anchor protein) K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Hlac_2205 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Hlac_2236 phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D Hlac_0731 dehydrogenase E1 component K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0139 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0140 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Hlac_0141 catalytic domain of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:hla00030]
D Hlac_2287 phosphoglucose isomerase (PGI) K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Hlac_0117 NAD-dependent epimerase/dehydratase K19243 azf; NAD+ dependent glucose-6-phosphate dehydrogenase [EC:1.1.1.388]
D Hlac_2457 NAD-dependent epimerase/dehydratase K19243 azf; NAD+ dependent glucose-6-phosphate dehydrogenase [EC:1.1.1.388]
D Hlac_1605 6-phosphogluconate dehydrogenase NAD-binding K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D Hlac_2632 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Hlac_2141 deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D Hlac_1418 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_2270 PfkB domain protein K26208 E2.7.1.239; alpha-D-ribose-1-phosphate 5-kinase (ATP) [EC:2.7.1.239]
D Hlac_2269 translation initiation factor, aIF-2BII family K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D Hlac_2178 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Hlac_0151 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D Hlac_2860 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D Hlac_1022 short-chain dehydrogenase/reductase SDR K00034 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D Hlac_0797 Alcohol dehydrogenase GroES domain protein K22969 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D Hlac_0165 glucose-methanol-choline oxidoreductase K19813 gdh; glucose dehydrogenase [EC:1.1.5.9]
D Hlac_1300 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D Hlac_2579 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D Hlac_0463 PfkB domain protein K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D Hlac_2870 PfkB domain protein K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D Hlac_1370 aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D Hlac_1050 aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D Hlac_1464 aldehyde ferredoxin oxidoreductase K03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]
D Hlac_0380 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Hlac_2459 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D Hlac_1274 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Hlac_2458 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
C 00040 Pentose and glucuronate interconversions [PATH:hla00040]
D Hlac_2037 Cupin 2 conserved barrel domain protein K26933 kdgF; unsaturated pyranuronate lyase [EC:4.2.99.25]
D Hlac_2239 Mannonate dehydratase K01686 uxuA; mannonate dehydratase [EC:4.2.1.8]
D Hlac_2419 oxidoreductase domain protein K14273 xdh; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) [EC:1.1.1.179]
D Hlac_2241 oxidoreductase domain protein K24442 xacA; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) [EC:1.1.1.424]
D Hlac_1560 oxidoreductase domain protein K24442 xacA; D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) [EC:1.1.1.424]
D Hlac_2242 Mandelate racemase/muconate lactonizing protein K14275 xad; D-xylonate dehydratase [EC:4.2.1.82]
D Hlac_2243 fumarylacetoacetate (FAA) hydrolase K14259 kdaD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141]
D Hlac_2240 Aldehyde Dehydrogenase K19588 dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
C 00051 Fructose and mannose metabolism [PATH:hla00051]
D Hlac_2162 PfkB domain protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_2458 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D Hlac_2459 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D Hlac_1274 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Hlac_0683 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:hla00052]
D Hlac_3491 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_0168 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_1073 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_1074 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_1104 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_0043 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D Hlac_2868 Glycoside hydrolase family 42 domain protein K12308 bgaB; beta-galactosidase [EC:3.2.1.23]
D Hlac_2869 Alpha-galactosidase-like protein K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]
D Hlac_2866 Mandelate racemase/muconate lactonizing protein K01684 dgoD; galactonate dehydratase [EC:4.2.1.6]
D Hlac_1300 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D Hlac_2579 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D Hlac_2493 Glycosyl hydrolase family 32 domain protein K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
C 00053 Ascorbate and aldarate metabolism [PATH:hla00053]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_2243 fumarylacetoacetate (FAA) hydrolase K14259 kdaD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141]
D Hlac_2240 Aldehyde Dehydrogenase K19588 dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
C 00500 Starch and sucrose metabolism [PATH:hla00500]
D Hlac_2493 Glycosyl hydrolase family 32 domain protein K01193 INV; beta-fructofuranosidase [EC:3.2.1.26]
D Hlac_2488 glycoside hydrolase family 68 K00692 sacB; levansucrase [EC:2.4.1.10]
D Hlac_0587 alpha amylase catalytic region K05343 treS; maltose alpha-D-glucosyltransferase / alpha-amylase [EC:5.4.99.16 3.2.1.1]
D Hlac_1504 alpha amylase catalytic region K01208 cd; cyclomaltodextrinase / maltogenic alpha-amylase / neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]
D Hlac_0545 glucan 14-alpha-glucosidase K01178 SGA1; glucoamylase [EC:3.2.1.3]
D Hlac_1505 4-alpha-glucanotransferase K00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]
D Hlac_0621 glycosyl transferase group 1 K16148 glgM; alpha-maltose-1-phosphate synthase [EC:2.4.1.342]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_0043 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D Hlac_2287 phosphoglucose isomerase (PGI) K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Hlac_2162 PfkB domain protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:hla00520]
D Hlac_2162 PfkB domain protein K00847 E2.7.1.4; fructokinase [EC:2.7.1.4]
D Hlac_1079 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Hlac_1084 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D Hlac_1083 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D Hlac_2874 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D Hlac_0043 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_1075 NAD-dependent epimerase/dehydratase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D Hlac_3491 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_0168 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_1073 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_1074 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_1104 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D Hlac_2287 phosphoglucose isomerase (PGI) K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00620 Pyruvate metabolism [PATH:hla00620]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Hlac_0928 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Hlac_0927 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Hlac_0731 dehydrogenase E1 component K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0139 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0140 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Hlac_0141 catalytic domain of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Hlac_1808 Alcohol dehydrogenase GroES domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3048 Alcohol dehydrogenase zinc-binding domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_0562 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Hlac_2540 Carbamoyl-phosphate synthase L chain ATP-binding K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D Hlac_1419 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_2589 acetyl-CoA hydrolase/transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D Hlac_0317 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Hlac_0211 Glyoxalase/bleomycin resistance protein/dioxygenase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D Hlac_1002 Glyoxalase/bleomycin resistance protein/dioxygenase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D Hlac_0383 beta-lactamase domain protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D Hlac_1525 malate dehydrogenase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Hlac_2205 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D Hlac_2311 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D Hlac_2236 phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D Hlac_0592 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0876 pyruvate carboxyltransferase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:hla00630]
D Hlac_2153 isocitrate lyase and phosphorylmutase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Hlac_0723 2-methylcitrate synthase/citrate synthase II K01647 CS; citrate synthase [EC:2.3.3.1]
D Hlac_0098 aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Hlac_3040 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_1013 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Hlac_2540 Carbamoyl-phosphate synthase L chain ATP-binding K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D Hlac_2536 carboxyl transferase K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D Hlac_2537 conserved hypothetical protein K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D Hlac_0510 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Hlac_1182 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_1016 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_2501 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D Hlac_1626 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D Hlac_2065 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D Hlac_1119 SPP-like hydrolase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D Hlac_1765 aminotransferase class V K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D Hlac_0912 ferredoxin-dependent glutamate synthase K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D Hlac_2374 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Hlac_2034 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Hlac_1611 glycine cleavage system P-protein K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D Hlac_1610 glycine cleavage system P-protein K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D Hlac_1240 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_0332 folate-binding protein YgfZ K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_1612 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D Hlac_0380 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Hlac_2109 iron-containing alcohol dehydrogenase K26209 K26209; glycolaldehyde reductase [EC:1.1.1.-]
D Hlac_2267 HAD-superfamily hydrolase, subfamily IA, variant 1 K26210 E3.1.3.109; ribulose-1,5-bisphosphate 5-phosphatase [EC:3.1.3.109]
D Hlac_2268 class II aldolase/adducin family protein K01636 K01636; ribulose 1-phosphate aldolase [EC:4.1.2.-]
D Hlac_0151 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D Hlac_2860 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase K01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]
D Hlac_1251 formyl transferase domain protein K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D Hlac_2285 Acetamidase/Formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
C 00640 Propanoate metabolism [PATH:hla00640]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0317 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Hlac_2540 Carbamoyl-phosphate synthase L chain ATP-binding K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D Hlac_2536 carboxyl transferase K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D Hlac_2537 conserved hypothetical protein K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D Hlac_2199 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1054 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1013 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Hlac_0510 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Hlac_1182 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_1016 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_2207 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Hlac_2208 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Hlac_0967 methylglyoxal synthase K01734 mgsA; methylglyoxal synthase [EC:4.2.3.3]
C 00650 Butanoate metabolism [PATH:hla00650]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_2460 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D Hlac_1117 Enoyl-CoA hydratase/isomerase K01715 crt; enoyl-CoA hydratase [EC:4.2.1.17]
D Hlac_1990 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Hlac_1989 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Hlac_1987 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Hlac_1988 succinate dehydrogenase, subunit D (membrane anchor protein) K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Hlac_2199 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1054 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1582 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Hlac_2589 acetyl-CoA hydrolase/transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Hlac_0928 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Hlac_0927 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Hlac_2313 Hydroxymethylglutaryl-coenzyme A synthase domain protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Hlac_1101 pyruvate carboxyltransferase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D Hlac_1536 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0875 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0874 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
C 00660 C5-Branched dibasic acid metabolism [PATH:hla00660]
D Hlac_1536 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0875 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0874 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Hlac_2207 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Hlac_2208 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Hlac_0588 pyruvate carboxyltransferase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D Hlac_1102 3-isopropylmalate dehydratase K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_0872 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_1103 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_0871 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_0870 isocitrate/isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:hla00562]
D Hlac_1794 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Hlac_0052 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Hlac_0683 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:hla00190]
D Hlac_0704 NADH-ubiquinone/plastoquinone oxidoreductase chain 3 K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D Hlac_0705 NADH-quinone oxidoreductase, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D Hlac_0706 NADH-ubiquinone oxidoreductase chain 49kDa K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D Hlac_0707 respiratory-chain NADH dehydrogenase subunit 1 K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D Hlac_0708 NADH-quinone oxidoreductase, chain I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D Hlac_0710 NADH dehydrogenase-like complex, subunit J2 K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D Hlac_0711 NADH-ubiquinone oxidoreductase chain 4L K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D Hlac_0712 proton-translocating NADH-quinone oxidoreductase, chain L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D Hlac_0713 proton-translocating NADH-quinone oxidoreductase, chain M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D Hlac_0714 proton-translocating NADH-quinone oxidoreductase, chain N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D Hlac_0937 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D Hlac_1990 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Hlac_1989 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Hlac_1987 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Hlac_1988 succinate dehydrogenase, subunit D (membrane anchor protein) K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Hlac_2407 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_2852 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_0791 conserved hypothetical protein K02277 coxD; cytochrome c oxidase subunit IV [EC:7.1.1.9]
D Hlac_2853 cytochrome c oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D Hlac_2413 cytochrome c oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D Hlac_0786 cytochrome c oxidase subunit I K15408 coxAC; cytochrome c oxidase subunit I+III [EC:7.1.1.9]
D Hlac_2412 cytochrome c oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D Hlac_0785 cytochrome c oxidase, subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D Hlac_1803 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9]
D Hlac_1116 hypothetical protein K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D Hlac_0281 ATP synthase, A subunit K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D Hlac_0282 H+transporting two-sector ATPase alpha/beta subunit central region K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D Hlac_0279 ATP synthase A1, C subunit K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D Hlac_0283 V-type ATPase, D subunit K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D Hlac_0278 H+transporting two-sector ATPase E subunit K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D Hlac_0280 Vacuolar H+transporting two-sector ATPase F subunit K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D Hlac_0275 ATP synthase H subunit K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D Hlac_0276 V-type ATPase 116 kDa subunit K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D Hlac_0277 H+transporting two-sector ATPase C subunit K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D Hlac_0304 Inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:hla00710]
D Hlac_2372 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Hlac_2371 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Hlac_1672 glyceraldehyde-3-phosphate dehydrogenase, type II K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D Hlac_2459 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D Hlac_2458 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D Hlac_2632 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D Hlac_0683 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D Hlac_2311 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D Hlac_2236 phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D Hlac_1525 malate dehydrogenase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:hla00720]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Hlac_0592 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Hlac_2311 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Hlac_2205 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D Hlac_1990 succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D Hlac_1989 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D Hlac_1987 succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D Hlac_1988 succinate dehydrogenase, subunit D (membrane anchor protein) K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D Hlac_2208 succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D Hlac_2207 succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D Hlac_1743 3-hydroxyacyl-CoA dehydrogenase NAD-binding K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0928 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D Hlac_0927 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D Hlac_2330 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D Hlac_0098 aconitate hydratase K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Hlac_3040 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D Hlac_1013 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Hlac_1182 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_1016 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_0510 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Hlac_1237 formate-tetrahydrofolate ligase FTHFS K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D Hlac_1624 tetrahydrofolate dehydrogenase/cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:hla00680]
D Hlac_1837 Alcohol dehydrogenase GroES domain protein K00148 fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46]
D Hlac_1238 formate dehydrogenase, alpha subunit K22516 fdhA; formate dehydrogenase (coenzyme F420) alpha subunit [EC:1.17.98.3 1.8.98.6]
D Hlac_2034 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Hlac_1765 aminotransferase class V K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D Hlac_0380 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Hlac_1825 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Hlac_2311 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Hlac_2459 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D Hlac_1274 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Hlac_2458 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D Hlac_1693 methenyltetrahydromethanopterin cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D Hlac_1680 Luciferase-like monooxygenase K00320 mer; 5,10-methylenetetrahydromethanopterin reductase [EC:1.5.98.2]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D Hlac_0592 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D Hlac_1851 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Hlac_2722 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_0393 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_2730 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D Hlac_2018 Radical SAM domain protein K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D Hlac_1894 Radical SAM domain protein K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D Hlac_1893 protein of unknown function DUF121 K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D Hlac_2334 LPPG domain protein containing protein K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D Hlac_1679 F420-dependent oxidoreductase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D Hlac_0591 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00910 Nitrogen metabolism [PATH:hla00910]
D Hlac_2285 Acetamidase/Formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
D Hlac_1404 major facilitator superfamily MFS_1 K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D Hlac_1335 DMSO reductase family type II enzyme, molybdopterin subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D Hlac_1336 DMSO reductase family type II enzyme, iron-sulfur subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D Hlac_1405 molybdopterin oxidoreductase K00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-]
D Hlac_0864 nitrite and sulphite reductase 4Fe-4S region K00366 nirA; ferredoxin-nitrite reductase [EC:1.7.7.1]
D Hlac_1407 nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00366 nirA; ferredoxin-nitrite reductase [EC:1.7.7.1]
D Hlac_1902 cytochrome b subunit of nitric oxide reductase K04561 norB; nitric oxide reductase subunit B [EC:1.7.2.5]
D Hlac_1165 cytochrome c oxidase subunit II K00376 nosZ; nitrous-oxide reductase [EC:1.7.2.4]
D Hlac_0802 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_1201 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_2374 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Hlac_0912 ferredoxin-dependent glutamate synthase K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D Hlac_1847 carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:hla00920]
D Hlac_2149 ABC-type nitrate/sulfonate/bicarbonate transport systems protein K15553 ssuA; sulfonate transport system substrate-binding protein
D Hlac_2148 binding-protein-dependent transport systems inner membrane component K15554 ssuC; sulfonate transport system permease protein
D Hlac_2147 ABC transporter related K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Hlac_1047 NADPH-dependent FMN reductase K00299 ssuE; FMN reductase [EC:1.5.1.38]
D Hlac_1106 phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D Hlac_3035 5'-Nucleotidase domain protein K17224 soxB; S-sulfosulfanyl-L-cysteine sulfohydrolase [EC:3.1.6.20]
D Hlac_2417 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D Hlac_1027 DoxX family protein K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D Hlac_0953 DoxX family protein K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D Hlac_0083 DoxX family protein K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D Hlac_1687 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1258 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1954 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1358 Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 cysK; cysteine synthase [EC:2.5.1.47]
D Hlac_2550 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D Hlac_1046 Luciferase-like monooxygenase K17228 sfnG; dimethylsulfone monooxygenase [EC:1.14.14.35]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:hla00061]
D Hlac_2540 Carbamoyl-phosphate synthase L chain ATP-binding K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D Hlac_2582 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Hlac_2212 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:hla00071]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_1850 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D Hlac_0221 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D Hlac_1498 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D Hlac_1318 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D Hlac_2578 acyl-CoA dehydrogenase domain protein K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D Hlac_2212 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Hlac_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Hlac_1808 Alcohol dehydrogenase GroES domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3048 Alcohol dehydrogenase zinc-binding domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis [PATH:hla00100]
D Hlac_1206 Squalene/phytoene synthase K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:hla00561]
D Hlac_0380 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1458 dihydroxyacetone kinase, DhaK subunit K05878 dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121]
D Hlac_1459 dihydroxyacetone kinase, L subunit K05879 dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121]
D Hlac_1460 dihydroxyacetone kinase, phosphotransfer subunit K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121]
D Hlac_1122 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D Hlac_1228 glycosyl transferase group 1 K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D Hlac_1075 NAD-dependent epimerase/dehydratase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D Hlac_2869 Alpha-galactosidase-like protein K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]
C 00564 Glycerophospholipid metabolism [PATH:hla00564]
D Hlac_1123 glycerol-3-phosphate dehydrogenase, anaerobic, A subunit K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D Hlac_1124 fumarate reductase/succinate dehydrogenase flavoprotein domain protein K00112 glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
D Hlac_1125 glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 glpC; glycerol-3-phosphate dehydrogenase subunit C
D Hlac_2518 phosphatidylserine decarboxylase-related K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D Hlac_0521 CDP-alcohol phosphatidyltransferase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D Hlac_2403 phospholipase D/Transphosphatidylase K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
D Hlac_0655 3-dehydroquinate synthase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D Hlac_0199 geranylgeranylglyceryl phosphate synthase family protein K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D Hlac_2079 UbiA prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D Hlac_0350 protein of unknown function DUF46 K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D Hlac_0607 CDP-alcohol phosphatidyltransferase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D Hlac_0926 FAD dependent oxidoreductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism [PATH:hla00600]
D Hlac_2869 Alpha-galactosidase-like protein K07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism [PATH:hla00592]
D Hlac_1850 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:hla00230]
D Hlac_2467 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D Hlac_0092 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D Hlac_1418 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_2178 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D Hlac_1477 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Hlac_1295 phosphoribosylamine/glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D Hlac_1553 phosphoribosylglycinamide synthetase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D Hlac_0925 phosphoribosylglycinamide formyltransferase K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D Hlac_0471 phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D Hlac_1250 phosphoribosylformylglycinamidine synthase, purS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D Hlac_1249 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Hlac_0862 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D Hlac_0700 phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D Hlac_0703 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D Hlac_1700 SAICAR synthetase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D Hlac_0924 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Hlac_2704 IMP cyclohydrolase K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
D Hlac_0254 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Hlac_1118 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Hlac_1292 Survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Hlac_2324 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Hlac_1209 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Hlac_1766 IMP dehydrogenase/GMP reductase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Hlac_1845 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Hlac_0603 protein of unknown function DUF84 K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73]
D Hlac_2200 Ham1 family protein K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D Hlac_0571 GMP synthase, small subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Hlac_0721 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Hlac_2593 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Hlac_2318 purine or other phosphorylase family 1 K26212 K26212; guanosine phosphorylase [EC:2.4.2.15]
D Hlac_2375 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Hlac_2944 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Hlac_2945 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Hlac_0805 adenylyl cyclase CyaB K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D Hlac_1323 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Hlac_1912 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Hlac_1343 nucleotide kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D Hlac_3318 hypothetical protein K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]
D Hlac_2053 histidine triad (HIT) protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
C 00240 Pyrimidine metabolism [PATH:hla00240]
D Hlac_1720 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Hlac_2325 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Hlac_1285 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Hlac_1284 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D Hlac_2077 dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D Hlac_0019 dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D Hlac_0584 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D Hlac_1586 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D Hlac_2386 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D Hlac_1845 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Hlac_2594 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D Hlac_1254 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D Hlac_1813 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D Hlac_1557 uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48]
D Hlac_1292 Survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Hlac_2324 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Hlac_0938 purine or other phosphorylase family 1 K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D Hlac_2717 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D Hlac_0939 cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D Hlac_0445 deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D Hlac_2375 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Hlac_2944 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Hlac_2945 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Hlac_1888 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D Hlac_0097 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Hlac_1567 thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
D Hlac_2166 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D Hlac_3269 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1099 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1507 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D Hlac_3270 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:hla00250]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_2272 Asparaginase/glutaminase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D Hlac_2332 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D Hlac_0611 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D Hlac_1765 aminotransferase class V K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D Hlac_0439 ornithine cyclodeaminase/mu-crystallin K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D Hlac_2619 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Hlac_2618 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Hlac_1323 adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D Hlac_0924 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D Hlac_1285 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D Hlac_1284 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D Hlac_2199 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1054 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1582 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Hlac_0802 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_1201 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_3373 Aldehyde Dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D Hlac_2374 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Hlac_1720 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Hlac_2325 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Hlac_1249 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Hlac_1079 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Hlac_1477 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:hla00260]
D Hlac_2743 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Hlac_1745 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Hlac_0155 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Hlac_2302 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D Hlac_0942 Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 thrC; threonine synthase [EC:4.2.3.1]
D Hlac_1608 Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 thrC; threonine synthase [EC:4.2.3.1]
D Hlac_2719 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D Hlac_1281 aromatic amino acid beta-eliminating lyase/threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48]
D Hlac_2034 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Hlac_1765 aminotransferase class V K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
D Hlac_0380 MOFRL domain protein K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D Hlac_1851 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D Hlac_2722 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_0393 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_2730 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D Hlac_1611 glycine cleavage system P-protein K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D Hlac_1610 glycine cleavage system P-protein K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D Hlac_1240 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_0332 folate-binding protein YgfZ K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_1612 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D Hlac_1546 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D Hlac_0289 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D Hlac_0349 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D Hlac_1273 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D Hlac_1272 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D Hlac_1048 aminotransferase class-III K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D Hlac_1051 creatinase K15783 doeA; ectoine hydrolase [EC:3.5.4.44]
C 00270 Cysteine and methionine metabolism [PATH:hla00270]
D Hlac_1358 Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 cysK; cysteine synthase [EC:2.5.1.47]
D Hlac_1546 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D Hlac_1763 Pyridoxal-5'-phosphate-dependent protein beta subunit K17216 mccA; cystathionine beta-synthase (O-acetyl-L-serine) [EC:2.5.1.134]
D Hlac_2107 Cobalamin-independent synthase MetE domain protein K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D Hlac_2108 Methionine synthase vitamin-B12 independent K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D Hlac_1394 S-adenosylmethionine synthetase (MAT) K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Hlac_0422 methylthioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D Hlac_0061 amidohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D Hlac_2201 amidohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D Hlac_0059 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D Hlac_2743 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Hlac_1745 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Hlac_0155 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Hlac_2550 homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D Hlac_2642 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D Hlac_2551 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D Hlac_0461 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0353 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_1687 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1258 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1954 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_2649 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D Hlac_2722 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_0393 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:hla00280]
D Hlac_0461 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0353 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0221 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D Hlac_1498 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D Hlac_1318 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D Hlac_1850 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D Hlac_2540 Carbamoyl-phosphate synthase L chain ATP-binding K11263 bccA; acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
D Hlac_2536 carboxyl transferase K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D Hlac_2537 conserved hypothetical protein K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D Hlac_1013 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D Hlac_0510 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D Hlac_1182 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_1016 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1101 pyruvate carboxyltransferase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_2313 Hydroxymethylglutaryl-coenzyme A synthase domain protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:hla00290]
D Hlac_0289 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D Hlac_0349 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D Hlac_0588 pyruvate carboxyltransferase K09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]
D Hlac_1102 3-isopropylmalate dehydratase K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_0872 3-isopropylmalate dehydratase, large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_1103 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_0871 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D Hlac_0870 isocitrate/isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D Hlac_1536 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0875 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0874 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Hlac_0873 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D Hlac_1247 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D Hlac_0461 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0353 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0876 pyruvate carboxyltransferase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:hla00300]
D Hlac_0155 homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D Hlac_2743 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Hlac_1745 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Hlac_0556 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D Hlac_0667 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D Hlac_0668 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D Hlac_0669 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D Hlac_3448 peptidase M20 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D Hlac_2425 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D Hlac_0672 peptidase M20 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D Hlac_0671 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D Hlac_0670 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D Hlac_2617 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D Hlac_2614 acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D Hlac_2615 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D Hlac_2613 acetylornithine and succinylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D Hlac_2612 N-acetyl-ornithine/N-acetyl-lysine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00310 Lysine degradation [PATH:hla00310]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_2578 acyl-CoA dehydrogenase domain protein K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_1582 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D Hlac_2590 FAD dependent oxidoreductase K15736 lhgO; (S)-2-hydroxyglutarate dehydrogenase [EC:1.1.5.13]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:hla00220]
D Hlac_2611 ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D Hlac_2619 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Hlac_2618 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Hlac_0934 arginase K01476 rocF; arginase [EC:3.5.3.1]
D Hlac_1249 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Hlac_2374 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Hlac_1720 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D Hlac_2325 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D Hlac_0802 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_1201 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_1412 GCN5-related N-acetyltransferase K00619 argA; amino-acid N-acetyltransferase [EC:2.3.1.1]
D Hlac_0829 peptidase M20 K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
D Hlac_2920 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
D Hlac_2664 peptidase M20 K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
D Hlac_2617 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D Hlac_2616 lysine biosynthesis enzyme LysX K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60]
D Hlac_2614 acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D Hlac_2615 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D Hlac_2613 acetylornithine and succinylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D Hlac_2612 N-acetyl-ornithine/N-acetyl-lysine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00330 Arginine and proline metabolism [PATH:hla00330]
D Hlac_1389 Creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D Hlac_0915 Creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D Hlac_0080 Creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D Hlac_2010 Pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D Hlac_1577 agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_2915 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1866 Acetamidase/Formamidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_0934 arginase K01476 rocF; arginase [EC:3.5.3.1]
D Hlac_0351 Proline dehydrogenase K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D Hlac_1150 Proline dehydrogenase K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D Hlac_3373 Aldehyde Dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:hla00340]
D Hlac_2637 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D Hlac_0369 phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D Hlac_2182 phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D Hlac_2699 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D Hlac_0375 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D Hlac_0547 imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D Hlac_2701 imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D Hlac_1344 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Hlac_1354 histidinol phosphate phosphatase HisJ family K04486 E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]
D Hlac_2478 histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00350 Tyrosine metabolism [PATH:hla00350]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_1344 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Hlac_0591 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Hlac_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Hlac_1808 Alcohol dehydrogenase GroES domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3048 Alcohol dehydrogenase zinc-binding domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_1582 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism [PATH:hla00360]
D Hlac_2460 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_1344 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Hlac_1548 catalase/peroxidase HPI K03782 katG; catalase-peroxidase [EC:1.11.1.21]
D Hlac_2915 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1866 Acetamidase/Formamidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00380 Tryptophan metabolism [PATH:hla00380]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_2578 acyl-CoA dehydrogenase domain protein K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_2915 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1866 Acetamidase/Formamidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1548 catalase/peroxidase HPI K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:hla00400]
D Hlac_1274 predicted phospho-2-dehydro-3-deoxyheptonate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D Hlac_1277 3-dehydroquinate synthase K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D Hlac_0600 dehydroquinase class I K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D Hlac_0456 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D Hlac_1876 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D Hlac_0687 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D Hlac_1114 chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D Hlac_1941 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Hlac_0459 Chorismate binding-like protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Hlac_0460 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Hlac_1942 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Hlac_1939 anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D Hlac_0088 glycosyl transferase family 3 K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D Hlac_1940 N-(5'phosphoribosyl)anthranilate isomerase (PRAI) K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D Hlac_1271 Indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D Hlac_1273 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D Hlac_1272 tryptophan synthase, beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D Hlac_1875 Chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D Hlac_1779 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D Hlac_0264 prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_1344 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:hla00410]
D Hlac_0591 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Hlac_2199 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1054 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1180 Protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D Hlac_3269 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1099 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1507 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D Hlac_3270 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
C 00430 Taurine and hypotaurine metabolism [PATH:hla00430]
D Hlac_2090 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Hlac_0439 ornithine cyclodeaminase/mu-crystallin K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D Hlac_0665 acetaldehyde dehydrogenase (acetylating) NAD-dependent K15515 sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81]
C 00440 Phosphonate and phosphinate metabolism
D Hlac_2544 PhnP-like protein K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:hla00450]
D Hlac_2107 Cobalamin-independent synthase MetE domain protein K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D Hlac_2108 Methionine synthase vitamin-B12 independent K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D Hlac_1546 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D Hlac_2248 cysteine desulfurase, SufS subfamily K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D Hlac_2304 aminotransferase class V K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D Hlac_1021 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Hlac_0323 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Hlac_0542 thioredoxin reductase-like protein K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Hlac_1741 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D Hlac_0447 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:hla00460]
D Hlac_2090 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Hlac_2272 Asparaginase/glutaminase K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D Hlac_2332 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D Hlac_2034 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Hlac_2285 Acetamidase/Formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
C 00470 D-Amino acid metabolism [PATH:hla00470]
D Hlac_1249 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D Hlac_1623 protein of unknown function DUF1611 K26272 dgcN; D-glutamate N-acetyltransferase [EC:2.3.1.312]
D Hlac_1622 Mandelate racemase/muconate lactonizing protein K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
D Hlac_0671 diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D Hlac_0670 diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D Hlac_2240 Aldehyde Dehydrogenase K19588 dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
C 00480 Glutathione metabolism [PATH:hla00480]
D Hlac_2090 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D Hlac_0952 glutamate--cysteine ligase GCS2 K06048 gshA; glutamate---cysteine ligase / carboxylate-amine ligase [EC:6.3.2.2 6.3.-.-]
D Hlac_2330 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D Hlac_1605 6-phosphogluconate dehydrogenase NAD-binding K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:hla00543]
D Hlac_3275 glycosyl transferase family 2 K11936 pgaC; poly-beta-1,6-N-acetyl-D-glucosamine synthase [EC:2.4.1.-]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:hla00730]
D Hlac_2988 phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D Hlac_2980 thiazole biosynthesis enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D Hlac_2151 thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D Hlac_1912 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Hlac_2986 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D Hlac_2987 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C 00740 Riboflavin metabolism [PATH:hla00740]
D Hlac_2188 GTP cyclohydrolase III K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D Hlac_0451 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D Hlac_0354 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D Hlac_0831 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D Hlac_0200 riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D Hlac_0355 protein of unknown function DUF120 K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D Hlac_2406 cytidyltransferase-related domain protein K14656 ribL; FAD synthetase [EC:2.7.7.2]
D Hlac_1047 NADPH-dependent FMN reductase K00299 ssuE; FMN reductase [EC:1.5.1.38]
D Hlac_2467 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D Hlac_0092 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C 00750 Vitamin B6 metabolism [PATH:hla00750]
D Hlac_1321 aldo/keto reductase K05275 E1.1.1.65; pyridoxine 4-dehydrogenase [EC:1.1.1.65]
D Hlac_0942 Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 thrC; threonine synthase [EC:4.2.3.1]
D Hlac_1608 Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 thrC; threonine synthase [EC:4.2.3.1]
D Hlac_2719 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D Hlac_2223 Vitamin B6 biosynthesis protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D Hlac_0370 SNO glutamine amidotransferase K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:hla00760]
D Hlac_2471 Quinolinate phosphoribosyl transferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D Hlac_1292 Survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Hlac_2324 stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D Hlac_1037 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D Hlac_0090 NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D Hlac_1563 CinA domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D Hlac_1661 ATP-NAD/AcoX kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D Hlac_0652 ATP-NAD/AcoX kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D Hlac_1098 isochorismatase hydrolase K13995 nicF; maleamate amidohydrolase [EC:3.5.1.107]
D Hlac_1582 Aldehyde Dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:hla00770]
D Hlac_1536 thiamine pyrophosphate protein domain protein TPP-binding K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0875 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D Hlac_0874 acetolactate synthase, small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D Hlac_0873 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D Hlac_1247 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D Hlac_2503 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D Hlac_0296 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D Hlac_0495 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169]
D Hlac_1180 Protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D Hlac_0837 phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D Hlac_0950 cytidyltransferase-related domain protein K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D Hlac_2394 Protein of unknown function DUF359 K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D Hlac_0461 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0353 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_3269 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1099 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1507 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D Hlac_3270 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D Hlac_0591 Pyridoxal-dependent decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:hla00780]
D Hlac_2582 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Hlac_1468 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:hla00785]
D Hlac_2099 lipoic acid synthetase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D Hlac_2127 biotin/lipoate A/B protein ligase K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D Hlac_0532 biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0731 dehydrogenase E1 component K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0139 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D Hlac_0140 Transketolase central region K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D Hlac_0141 catalytic domain of components of various dehydrogenase complexes K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D Hlac_1611 glycine cleavage system P-protein K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D Hlac_1610 glycine cleavage system P-protein K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D Hlac_1240 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_0332 folate-binding protein YgfZ K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_1612 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:hla00790]
D Hlac_1387 dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D Hlac_0325 dihydropteroate synthase K24102 folCP; dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
D Hlac_2167 dihydrofolate reductase region K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D Hlac_0438 dihydrofolate reductase region K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D Hlac_0517 conserved hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Hlac_3057 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Hlac_1646 transcriptional coactivator/pterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D Hlac_3058 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Hlac_3292 ExsB family protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Hlac_3059 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Hlac_2276 protein of unknown function DUF198 K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D Hlac_0062 Protein of unknown function DUF372 K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D Hlac_1388 protein of unknown function DUF115 K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D Hlac_2038 beta-ribofuranosylaminobenzene 5'-phosphate synthase family K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D Hlac_1859 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D Hlac_1236 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D Hlac_2385 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D Hlac_1943 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D Hlac_2122 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D Hlac_2123 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D Hlac_2224 molybdopterin-guanine dinucleotide biosynthesis protein A K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:hla00670]
D Hlac_2167 dihydrofolate reductase region K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D Hlac_0438 dihydrofolate reductase region K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D Hlac_1237 formate-tetrahydrofolate ligase FTHFS K01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]
D Hlac_1624 tetrahydrofolate dehydrogenase/cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D Hlac_2034 glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D Hlac_0925 phosphoribosylglycinamide formyltransferase K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D Hlac_1070 Methionyl-tRNA formyltransferase-like protein K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D Hlac_1240 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_0332 folate-binding protein YgfZ K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D Hlac_2166 thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D Hlac_1251 formyl transferase domain protein K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D Hlac_1375 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:hla00860]
D Hlac_2322 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hlac_2132 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D Hlac_2622 aminotransferase class-III K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Hlac_0015 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D Hlac_2252 porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D Hlac_2254 Uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D Hlac_2193 Chlorite dismutase K25033 chdC; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
D Hlac_2253 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D Hlac_2131 siroheme synthase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D Hlac_0086 putative transcriptional regulator, AsnC family K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D Hlac_2130 putative transcriptional regulator, AsnC family K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D Hlac_2081 Radical SAM domain protein K22226 ahbC; Fe-coproporphyrin III synthase
D Hlac_1215 Radical SAM domain protein K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D Hlac_2407 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_2852 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_1803 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9]
D Hlac_0262 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D Hlac_3470 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D Hlac_3477 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D Hlac_3473 precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D Hlac_3474 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D Hlac_3476 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D Hlac_3475 cobalamin (vitamin B12) biosynthesis CbiG protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D Hlac_3478 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D Hlac_3459 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D Hlac_3460 Precorrin-8X methylmutase CbiC/CobH K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D Hlac_0231 cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D Hlac_3461 CobN/magnesium chelatase K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D Hlac_2349 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D Hlac_0237 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D Hlac_0238 cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D Hlac_0232 cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D Hlac_0236 protein of unknown function DUF105 K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90]
D Hlac_0234 GTP:adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D Hlac_0233 cobalamin 5'-phosphate synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D Hlac_0235 aminotransferase class I and II K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D Hlac_3462 magnesium chelatase ChlI subunit K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1]
D Hlac_2218 Ferritin Dps family protein K03594 bfr; bacterioferritin [EC:1.16.3.1]
D Hlac_3033 multicopper oxidase type 3 K22552 mmcO; multicopper oxidase [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:hla00130]
D Hlac_1487 isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D Hlac_1290 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D Hlac_1174 Mandelate racemase/muconate lactonizing protein K02549 menC; o-succinylbenzoate synthase [EC:4.2.1.113]
D Hlac_1497 AMP-dependent synthetase and ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D Hlac_2150 naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36]
D Hlac_1175 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:hla00900]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_2313 Hydroxymethylglutaryl-coenzyme A synthase domain protein K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D Hlac_2019 3-hydroxy-3-methylglutaryl Coenzyme A reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D Hlac_1829 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D Hlac_1434 GHMP kinase K17942 pmd; phosphomevalonate decarboxylase [EC:4.1.1.99]
D Hlac_1830 aspartate/glutamate/uridylate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D Hlac_1959 NUDIX hydrolase K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D Hlac_2048 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Hlac_0241 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Hlac_1652 Di-trans-poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D Hlac_2063 undecaprenyl diphosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:hla00909]
D Hlac_1206 Squalene/phytoene synthase K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis [PATH:hla00906]
D Hlac_2476 Squalene/phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D Hlac_1898 UbiA prenyltransferase K20616 lyeJ; lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) [EC:2.5.1.150]
D Hlac_1897 phytoene desaturase K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D Hlac_1899 carotene biosynthesis associated membrane protein K08977 cruF; bisanhydrobacterioruberin hydratase [EC:4.2.1.161]
D Hlac_2731 lycopene cyclase domain protein K22502 crtY; lycopene beta-cyclase [EC:5.5.1.19]
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation [PATH:hla00907]
D Hlac_2352 short-chain dehydrogenase/reductase SDR K13775 atuG; citronellol/citronellal dehydrogenase
D Hlac_1101 pyruvate carboxyltransferase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D Hlac_1850 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
D Hlac_1775 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Hlac_1080 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Hlac_1083 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D Hlac_2874 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D Hlac_1487 isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:hla00261]
D Hlac_2743 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D Hlac_1745 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D Hlac_0556 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D Hlac_0667 dihydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D Hlac_0668 dihydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:hla00521]
D Hlac_0043 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
D Hlac_2256 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D Hlac_1794 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Hlac_0052 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D Hlac_1775 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Hlac_1080 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Hlac_1083 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D Hlac_2874 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D Hlac_0043 ROK family protein K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis
D Hlac_1775 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Hlac_1080 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D Hlac_1083 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D Hlac_2874 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00401 Novobiocin biosynthesis [PATH:hla00401]
D Hlac_1779 prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_1344 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D Hlac_1941 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Hlac_0459 Chorismate binding-like protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Hlac_0460 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Hlac_1942 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D Hlac_2582 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites [PATH:hla00999]
D Hlac_1394 S-adenosylmethionine synthetase (MAT) K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D Hlac_0456 shikimate 5-dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:hla00362]
D Hlac_0720 alpha/beta hydrolase fold protein K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24]
D Hlac_2379 alpha/beta hydrolase fold protein K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24]
D Hlac_1850 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D Hlac_0509 Glyoxalase/bleomycin resistance protein/dioxygenase K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
D Hlac_1176 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D Hlac_2578 acyl-CoA dehydrogenase domain protein K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D Hlac_2460 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:hla00627]
D Hlac_2915 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1866 Acetamidase/Formamidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1419 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:hla00625]
D Hlac_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Hlac_1808 Alcohol dehydrogenase GroES domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3048 Alcohol dehydrogenase zinc-binding domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3047 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1152 Aldehyde Dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D Hlac_1837 Alcohol dehydrogenase GroES domain protein K00148 fdhA; glutathione-independent formaldehyde dehydrogenase [EC:1.2.1.46]
D Hlac_2517 haloacid dehalogenase, type II K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:hla00361]
D Hlac_0509 Glyoxalase/bleomycin resistance protein/dioxygenase K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
D Hlac_2517 haloacid dehalogenase, type II K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
C 00623 Toluene degradation
C 00622 Xylene degradation [PATH:hla00622]
D Hlac_0509 Glyoxalase/bleomycin resistance protein/dioxygenase K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
C 00633 Nitrotoluene degradation
D Hlac_0891 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D Hlac_0890 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
D Hlac_1850 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 00643 Styrene degradation [PATH:hla00643]
D Hlac_2915 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_1866 Acetamidase/Formamidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D Hlac_0509 Glyoxalase/bleomycin resistance protein/dioxygenase K07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:hla00626]
D Hlac_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D Hlac_1808 Alcohol dehydrogenase GroES domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
D Hlac_3048 Alcohol dehydrogenase zinc-binding domain protein K00001 E1.1.1.1; alcohol dehydrogenase [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:hla03020]
D Hlac_0106 RNA polymerase Rpb2 domain 6 K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D Hlac_0107 RNA polymerase beta subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D Hlac_0105 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D Hlac_0104 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D Hlac_1819 RNA polymerase insert K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D Hlac_0620 RNA polymerase dimerisation K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D Hlac_2396 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D Hlac_2278 RNA polymerase Rpb4 K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D Hlac_0108 RNA polymerase Rpb5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D Hlac_1824 RNA polymerase Rpb6 K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D Hlac_1823 RNA polymerase, N/8 Kd subunit K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D Hlac_0565 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:hla03022]
D Hlac_1327 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_0072 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_1495 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_1513 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_2880 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_0601 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_0309 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_3140 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_3420 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_2629 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_3287 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_1523 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_3413 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_2818 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_1708 Transcription factor TFIIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D Hlac_1535 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D Hlac_0816 helicase c2 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_2627 DEAD_2 domain protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:hla03010]
D Hlac_1826 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D Hlac_2443 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D Hlac_1817 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D Hlac_2429 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D Hlac_0100 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D Hlac_2434 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D Hlac_1822 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D Hlac_0157 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D Hlac_1818 ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D Hlac_0101 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12
D Hlac_1816 ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D Hlac_2435 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D Hlac_0615 Ribosomal S13S15 domain protein K02956 RP-S15; small subunit ribosomal protein S15
D Hlac_2440 ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D Hlac_2445 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D Hlac_0618 ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D Hlac_2437 Ribosomal protein S4E, central domain protein K02987 RP-S4e; small subunit ribosomal protein S4e
D Hlac_2128 Ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D Hlac_1967 ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D Hlac_2338 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D Hlac_2312 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D Hlac_2393 Ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D Hlac_1010 Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D Hlac_1843 Ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D Hlac_2535 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D Hlac_2446 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D Hlac_2449 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D Hlac_2436 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D Hlac_2433 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D Hlac_2534 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D Hlac_1983 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D Hlac_2533 ribosomal protein 60S K02869 RP-L12; large subunit ribosomal protein L12
D Hlac_1821 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D Hlac_2439 ribosomal protein L14b/L23e K02874 RP-L14; large subunit ribosomal protein L14
D Hlac_2427 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D Hlac_2430 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18
D Hlac_2444 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D Hlac_2447 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23
D Hlac_2438 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D Hlac_2442 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D Hlac_2428 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30
D Hlac_2448 ribosomal protein L4/L1e K02930 RP-L4e; large subunit ribosomal protein L4e
D Hlac_1842 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Hlac_0057 ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D Hlac_0413 Ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D Hlac_1820 ribosomal protein L15 K02883 RP-L18e; large subunit ribosomal protein L18e
D Hlac_2431 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D Hlac_2277 Ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D Hlac_1844 Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D Hlac_0827 Ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D Hlac_2432 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D Hlac_2045 Ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D Hlac_0564 Ribosomal L37ae protein K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D Hlac_0828 Ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D Hlac_0373 Ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Hlac_1011 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D Hlac_0823 Ribosomal LX protein K02944 RP-LX; large subunit ribosomal protein LX
D Hlac_R0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0031 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0058 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0003 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0029 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0060 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0004 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0028 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0061 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:hla00970]
D Hlac_R0013 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0059 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0030 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0021 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0010 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0056 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0022 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0039 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0012 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Hlac_R0008 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Hlac_R0009 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Hlac_R0005 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Hlac_R0057 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Hlac_R0015 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Hlac_R0050 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Hlac_R0032 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Hlac_R0023 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0047 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0052 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0037 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0041 tRNA-His K14226 tRNA-His; tRNA His
D Hlac_R0026 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Hlac_R0024 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0027 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0044 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0054 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0046 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0040 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Hlac_R0055 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Hlac_R0019 tRNA-Met K14230 tRNA-Met; tRNA Met
D Hlac_R0011 tRNA-Met K14230 tRNA-Met; tRNA Met
D Hlac_R0049 tRNA-Met K14230 tRNA-Met; tRNA Met
D Hlac_R0006 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Hlac_R0018 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Hlac_R0034 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Hlac_R0007 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Hlac_R0042 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Hlac_R0036 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0043 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0014 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0016 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0048 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Hlac_R0017 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Hlac_R0033 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Hlac_R0025 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Hlac_R0038 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Hlac_R0035 tRNA-Val K14237 tRNA-Val; tRNA Val
D Hlac_R0053 tRNA-Val K14237 tRNA-Val; tRNA Val
D Hlac_R0051 tRNA-Val K14237 tRNA-Val; tRNA Val
D Hlac_2322 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hlac_0835 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Hlac_0431 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Hlac_0834 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Hlac_2140 glutamyl-tRNA(Gln) amidotransferase, subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D Hlac_1472 aspartyl-tRNA(Asn) amidotransferase, B subunit K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D Hlac_2498 Threonyl/alanyl tRNA synthetase SAD K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hlac_0719 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hlac_1657 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Hlac_0293 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Hlac_1764 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Hlac_2073 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Hlac_0291 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Hlac_0447 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Hlac_1070 Methionyl-tRNA formyltransferase-like protein K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D Hlac_0018 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Hlac_0366 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Hlac_0887 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Hlac_2387 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Hlac_0169 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Hlac_0777 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Hlac_2219 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Hlac_2671 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Hlac_2670 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Hlac_2505 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Hlac_1863 aminoacyl-tRNA synthetase class Ib K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:hla03060]
D Hlac_2426 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Hlac_1964 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D Hlac_1963 SecD/SecF/SecDF export membrane protein K03074 secF; preprotein translocase subunit SecF
D Hlac_0496 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Hlac_R0020 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA
D Hlac_0821 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Hlac_0900 protein translocase SEC61 complex, gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Hlac_0717 Ribonucleoprotein complex SRP, Srp19 component K03105 SRP19; signal recognition particle subunit SRP19
D Hlac_3445 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_0661 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_1224 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_2712 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_0988 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Hlac_2608 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
D Hlac_2609 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
D Hlac_2822 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0002 Signal peptidase I-like protein K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0480 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_1241 hypothetical protein K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0128 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:hla04122]
D Hlac_1687 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1258 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_1954 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D Hlac_2416 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Hlac_2421 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Hlac_2385 molybdopterin biosynthesis MoaE protein K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D Hlac_1859 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D Hlac_1542 MoaD family protein K03636 moaD; sulfur-carrier protein
D Hlac_1996 MoaD family protein K03636 moaD; sulfur-carrier protein
D Hlac_1264 conserved hypothetical protein K03636 moaD; sulfur-carrier protein
D Hlac_1236 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D Hlac_1943 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D Hlac_0432 thiamine biosynthesis protein ThiS (sulfur donor) K03154 thiS; sulfur carrier protein
C 03050 Proteasome [PATH:hla03050]
D Hlac_0185 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D Hlac_2011 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D Hlac_0963 20S proteasome A and B subunits K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Hlac_2172 20S proteasome A and B subunits K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Hlac_0608 20S proteasome A and B subunits K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Hlac_1448 20S proteasome A and B subunits K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:hla03018]
D Hlac_1825 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Hlac_0359 ribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1]
D Hlac_2047 beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Hlac_0682 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:hla03030]
D Hlac_2135 TOPRIM domain protein K02316 dnaG; DNA primase [EC:2.7.7.101]
D Hlac_0307 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Hlac_1966 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Hlac_2645 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Hlac_0177 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Hlac_3264 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Hlac_0003 metallophosphoesterase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D Hlac_0150 DNA polymerase II, large subunit DP2 K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D Hlac_2510 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Hlac_0740 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Hlac_1798 DNA primase, small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D Hlac_2529 DNA primase, large subunit K18882 priL; DNA primase large subunit
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Hlac_2653 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D Hlac_0384 Replication factor C K04801 rfcS; replication factor C small subunit
D Hlac_2519 AAA ATPase central domain protein K04801 rfcS; replication factor C small subunit
D Hlac_1810 AAA ATPase central domain protein K04800 rfcL; replication factor C large subunit
D Hlac_1698 DNA replication factor Dna2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D Hlac_1613 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03410 Base excision repair [PATH:hla03410]
D Hlac_1517 8-oxoguanine DNA glycosylase domain protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D Hlac_0954 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Hlac_1044 HhH-GPD family protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Hlac_2002 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D Hlac_2653 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D Hlac_1613 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Hlac_1742 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D Hlac_0379 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Hlac_1992 conserved hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Hlac_0531 apurinic endonuclease Apn1 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D Hlac_2552 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Hlac_2645 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:hla03420]
D Hlac_2607 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D Hlac_2638 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D Hlac_2725 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D Hlac_0203 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Hlac_2645 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Hlac_1535 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D Hlac_0816 helicase c2 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_2627 DEAD_2 domain protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Hlac_2653 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
C 03430 Mismatch repair [PATH:hla03430]
D Hlac_0119 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Hlac_2226 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Hlac_1501 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Hlac_2604 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Hlac_2227 MutL dimerisation K03572 mutL; DNA mismatch repair protein MutL
D Hlac_0629 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Hlac_0203 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Hlac_2552 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Hlac_2645 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Hlac_1929 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3321 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3349 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_2653 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
C 03440 Homologous recombination [PATH:hla03440]
D Hlac_2552 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
C 03450 Non-homologous end-joining
D Hlac_1613 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1 [PATH:hla03250]
D Hlac_1668 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D Hlac_2395 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4
D Hlac_0899 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:hla02010]
D Hlac_2057 molybdate transport protein K05772 tupA; tungstate transport system substrate-binding protein
D Hlac_3454 molybdate transport protein K05772 tupA; tungstate transport system substrate-binding protein
D Hlac_2056 binding-protein-dependent transport systems inner membrane component K05773 tupB; tungstate transport system permease protein
D Hlac_3453 binding-protein-dependent transport systems inner membrane component K05773 tupB; tungstate transport system permease protein
D Hlac_2055 ABC transporter related K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D Hlac_3452 ABC transporter related K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D Hlac_1225 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D Hlac_1226 NifC-like ABC-type porter K15496 wtpB; molybdate/tungstate transport system permease protein
D Hlac_1227 ABC transporter related K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D Hlac_2149 ABC-type nitrate/sulfonate/bicarbonate transport systems protein K15553 ssuA; sulfonate transport system substrate-binding protein
D Hlac_2148 binding-protein-dependent transport systems inner membrane component K15554 ssuC; sulfonate transport system permease protein
D Hlac_2147 ABC transporter related K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Hlac_0162 ABC-type iron(III) transport system,substrate-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D Hlac_0167 binding-protein-dependent transport systems inner membrane component K02011 afuB; iron(III) transport system permease protein
D Hlac_0472 ABC transporter related K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D Hlac_2697 ABC transporter, periplasmic binding protein, thiB subfamily K02064 thiB; thiamine transport system substrate-binding protein
D Hlac_2696 binding-protein-dependent transport systems inner membrane component K02063 thiP; thiamine transport system permease protein
D Hlac_2695 ABC transporter related K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D Hlac_2486 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_2523 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_0633 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_2865 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_0632 extracellular solute-binding protein family 1 K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D Hlac_0631 binding-protein-dependent transport systems inner membrane component K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Hlac_0630 binding-protein-dependent transport systems inner membrane component K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Hlac_2862 extracellular solute-binding protein family 1 K10188 lacE; lactose/L-arabinose transport system substrate-binding protein
D Hlac_2863 binding-protein-dependent transport systems inner membrane component K10189 lacF; lactose/L-arabinose transport system permease protein
D Hlac_2864 binding-protein-dependent transport systems inner membrane component K10190 lacG; lactose/L-arabinose transport system permease protein
D Hlac_2482 extracellular solute-binding protein family 1 K10236 thuE; trehalose/maltose transport system substrate-binding protein
D Hlac_2484 binding-protein-dependent transport systems inner membrane component K10237 thuF; trehalose/maltose transport system permease protein
D Hlac_2485 binding-protein-dependent transport systems inner membrane component K10238 thuG; trehalose/maltose transport system permease protein
D Hlac_1417 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D Hlac_1415 inner-membrane translocator K23535 nupB; general nucleoside transport system permease protein
D Hlac_1414 inner-membrane translocator K23536 nupC; general nucleoside transport system permease protein
D Hlac_1416 ABC transporter related K23537 nupA; general nucleoside transport system ATP-binding protein
D Hlac_2520 extracellular solute-binding protein family 1 K17315 gtsA; glucose/mannose transport system substrate-binding protein
D Hlac_2521 binding-protein-dependent transport systems inner membrane component K17316 gtsB; glucose/mannose transport system permease protein
D Hlac_2522 binding-protein-dependent transport systems inner membrane component K17317 gtsC; glucose/mannose transport system permease protein
D Hlac_3551 ABC-type phosphate transport system, substrate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Hlac_0502 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Hlac_3552 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein
D Hlac_0503 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein
D Hlac_3553 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein
D Hlac_0504 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein
D Hlac_3554 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Hlac_0505 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Hlac_0378 phosphate/phosphonate ABC transporter periplasmic substrate-binding protein K02044 phnD; phosphonate transport system substrate-binding protein
D Hlac_0376 phosphonate ABC transporter, inner membrane subunit K02042 phnE; phosphonate transport system permease protein
D Hlac_0377 ABC transporter related K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D Hlac_0229 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_1149 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_1092 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_0228 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_1091 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_1148 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_2918 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_2098 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_0227 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_1090 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_2097 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_2919 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_1147 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_0226 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_1146 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_2916 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_2096 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_1145 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_0225 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2095 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2917 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_1191 periplasmic solute binding protein K09815 znuA; zinc transport system substrate-binding protein
D Hlac_0851 periplasmic solute binding protein K09815 znuA; zinc transport system substrate-binding protein
D Hlac_1193 ABC-3 protein K09816 znuB; zinc transport system permease protein
D Hlac_0853 ABC-3 protein K09816 znuB; zinc transport system permease protein
D Hlac_1192 ABC transporter related K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Hlac_0852 ABC transporter related K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Hlac_0498 BioY protein K03523 bioY; biotin transport system substrate-specific component
D Hlac_0500 cobalt transport protein K16783 bioN; biotin transport system permease protein
D Hlac_0499 ABC transporter related K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D Hlac_1161 ABC-type transport system involved in multi-copper enzyme maturation permease component K19341 nosY; Cu-processing system permease protein
D Hlac_1724 copper ABC transporter permease K19341 nosY; Cu-processing system permease protein
D Hlac_1722 copper-binding protein K07218 nosD; nitrous oxidase accessory protein
D Hlac_1723 ABC transporter related K19340 nosF; Cu-processing system ATP-binding protein
C 02060 Phosphotransferase system (PTS) [PATH:hla02060]
D Hlac_1461 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D Hlac_1462 phosphocarrier, HPr family K02784 ptsH; phosphocarrier protein HPr
C 03070 Bacterial secretion system [PATH:hla03070]
D Hlac_1964 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D Hlac_1963 SecD/SecF/SecDF export membrane protein K03074 secF; preprotein translocase subunit SecF
D Hlac_2426 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Hlac_0821 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Hlac_0496 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Hlac_0988 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Hlac_2608 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
D Hlac_2609 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:hla02020]
D Hlac_3551 ABC-type phosphate transport system, substrate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Hlac_0502 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Hlac_1803 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9]
D Hlac_2488 glycoside hydrolase family 68 K00692 sacB; levansucrase [EC:2.4.1.10]
D Hlac_0213 HpcH/HpaI aldolase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D Hlac_0803 HpcH/HpaI aldolase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D Hlac_2336 triphosphoribosyl-dephospho-CoA protein K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D Hlac_1335 DMSO reductase family type II enzyme, molybdopterin subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D Hlac_1336 DMSO reductase family type II enzyme, iron-sulfur subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D Hlac_2374 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_2264 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D Hlac_1029 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_1681 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_0084 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2290 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2726 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2261 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW
D Hlac_2263 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Hlac_0694 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2561 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2262 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D Hlac_1116 hypothetical protein K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D Hlac_0934 arginase K01476 rocF; arginase [EC:3.5.3.1]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:hla02024]
D Hlac_1941 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Hlac_0459 Chorismate binding-like protein K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D Hlac_0460 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Hlac_1942 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D Hlac_0229 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_1149 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_1092 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_0228 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_1091 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_1148 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_2918 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_2098 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_0227 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_1090 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_2097 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_2919 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_1147 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_0226 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_1146 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_2916 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_2096 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_1145 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_0225 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2095 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2917 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2721 beta-lactamase domain protein K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81]
D Hlac_2212 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Hlac_0069 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0244 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0252 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_3666 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0133 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0674 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0068 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0245 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0251 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_3265 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0675 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0067 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_0250 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_3266 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_0246 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_0066 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0243 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0249 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_3267 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0677 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0248 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D Hlac_2426 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Hlac_0821 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Hlac_0496 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis [PATH:hla02030]
D Hlac_1029 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_1681 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_0084 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2290 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2726 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2263 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Hlac_2261 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW
D Hlac_0694 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2561 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2562 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Hlac_2262 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D Hlac_2563 CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D Hlac_2264 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D Hlac_1825 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism [PATH:hla04980]
D Hlac_2349 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D Hlac_0511 LAO/AO transport system ATPase K07588 MMAA; GTPase [EC:3.6.5.-]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
D Hlac_1668 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:hla01000]
C 01001 Protein kinases [BR:hla01001]
D Hlac_2392 metalloendopeptidase, glycoprotease family K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D Hlac_2660 protein of unknown function RIO1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D Hlac_0533 protein of unknown function RIO1 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D Hlac_1519 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D Hlac_1809 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D Hlac_1908 multi-sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D Hlac_2263 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:hla01009]
D Hlac_0818 Translation initiation factor IF2/IF5 K03238 EIF2S2; translation initiation factor 2 subunit 2
D Hlac_0059 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D Hlac_2730 phosphoserine phosphatase SerB K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:hla01002]
D Hlac_2136 peptidase A24A prepilin type IV K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D Hlac_0571 GMP synthase, small subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Hlac_0721 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Hlac_2593 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D Hlac_1477 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D Hlac_0912 ferredoxin-dependent glutamate synthase K00284 GLU; glutamate synthase (ferredoxin) [EC:1.4.7.1]
D Hlac_1079 glucosamine/fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D Hlac_0611 asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D Hlac_2222 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124]
D Hlac_0898 conserved hypothetical protein K24447 artA; archaeosortase A [EC:3.4.22.-]
D Hlac_2468 Abortive infection protein K07052 K07052; CAAX protease family protein
D Hlac_2288 Abortive infection protein K07052 K07052; CAAX protease family protein
D Hlac_2686 oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D Hlac_3448 peptidase M20 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D Hlac_2425 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D Hlac_0672 peptidase M20 K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D Hlac_1411 amidohydrolase K12940 abgA; aminobenzoyl-glutamate utilization protein A
D Hlac_1053 amidohydrolase K12940 abgA; aminobenzoyl-glutamate utilization protein A
D Hlac_1057 amidohydrolase K12940 abgA; aminobenzoyl-glutamate utilization protein A
D Hlac_2052 methionine aminopeptidase, type II K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D Hlac_1328 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D Hlac_0202 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D Hlac_2014 peptidase M29 aminopeptidase II K19689 ampS; aminopeptidase [EC:3.4.11.-]
D Hlac_2666 peptidase M29 aminopeptidase II K19689 ampS; aminopeptidase [EC:3.4.11.-]
D Hlac_1280 peptidase M32 carboxypeptidase Taq metallopeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D Hlac_2015 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D Hlac_2574 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D Hlac_1110 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D Hlac_0334 peptidase zinc-dependent K06974 amzA; archaemetzincin [EC:3.4.-.-]
D Hlac_1268 Mov34/MPN/PAD-1 family protein K20110 JAMM1; desampylase [EC:3.4.19.15]
D Hlac_0042 conserved hypothetical protein K24131 prsW; protease PrsW [EC:3.4.-.-]
D Hlac_2196 peptidase S8 and S53 subtilisin kexin sedolisin K01342 aprE; subtilisin [EC:3.4.21.62]
D Hlac_1038 Sigma 54 interacting domain protein K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D Hlac_2822 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0002 Signal peptidase I-like protein K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0480 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_1241 hypothetical protein K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0128 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D Hlac_0454 signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-]
D Hlac_0599 AN1-type Zinc finger protein K07059 K07059; rhomboid family protein
D Hlac_0963 20S proteasome A and B subunits K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Hlac_2172 20S proteasome A and B subunits K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Hlac_0608 20S proteasome A and B subunits K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Hlac_1448 20S proteasome A and B subunits K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Hlac_2332 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D Hlac_2090 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C 01003 Glycosyltransferases [BR:hla01003]
D Hlac_0696 glycosyl transferase family 2 K23684 aglJ; dolichol-phosphate hexosyltransferase [EC:2.4.1.-]
D Hlac_1063 glycosyl transferase family 2 K22844 aglG; glucosyl-dolichyl phosphate glucuronosyltransferase [EC:2.4.1.356]
D Hlac_0160 conserved hypothetical protein K23683 aglD; glycosyltransferase AglD [EC:2.4.1.-]
D Hlac_1062 Oligosaccharyl transferase STT3 subunit K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D Hlac_1228 glycosyl transferase group 1 K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D Hlac_0621 glycosyl transferase group 1 K16148 glgM; alpha-maltose-1-phosphate synthase [EC:2.4.1.342]
D Hlac_2488 glycoside hydrolase family 68 K00692 sacB; levansucrase [EC:2.4.1.10]
D Hlac_3275 glycosyl transferase family 2 K11936 pgaC; poly-beta-1,6-N-acetyl-D-glucosamine synthase [EC:2.4.1.-]
D Hlac_1456 glycosyltransferase-like protein K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:hla01011]
D Hlac_0898 conserved hypothetical protein K24447 artA; archaeosortase A [EC:3.4.22.-]
C 01004 Lipid biosynthesis proteins [BR:hla01004]
D Hlac_2582 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D Hlac_1304 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_1306 acetate/CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0990 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D Hlac_0317 CoA-binding domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D Hlac_2212 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:hla01006]
D Hlac_2048 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Hlac_0241 Polyprenyl synthetase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D Hlac_1652 Di-trans-poly-cis-decaprenylcistransferase K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D Hlac_1206 Squalene/phytoene synthase K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
D Hlac_2476 Squalene/phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D Hlac_1175 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D Hlac_2407 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_2852 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:hla01007]
D Hlac_2387 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Hlac_2322 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hlac_2505 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Hlac_1863 aminoacyl-tRNA synthetase class Ib K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Hlac_0291 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Hlac_0169 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Hlac_0447 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Hlac_0887 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Hlac_0018 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Hlac_0366 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Hlac_1657 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Hlac_2219 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Hlac_0293 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Hlac_2073 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Hlac_0777 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Hlac_1764 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Hlac_2498 Threonyl/alanyl tRNA synthetase SAD K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hlac_0719 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hlac_2671 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Hlac_2670 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Hlac_1393 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0832 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_0930 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D Hlac_3535 aminotransferase class I and II K10907 K10907; aminotransferase [EC:2.6.1.-]
D Hlac_1319 aminotransferase class I and II K10907 K10907; aminotransferase [EC:2.6.1.-]
D Hlac_1344 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D Hlac_2613 acetylornithine and succinylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D Hlac_2199 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1054 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D Hlac_1048 aminotransferase class-III K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D Hlac_2622 aminotransferase class-III K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D Hlac_0461 aminotransferase class IV K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_0353 branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D Hlac_1765 aminotransferase class V K00830 AGXT; alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:hla00194]
D Hlac_1173 halocyanin domain protein K02638 petE; plastocyanin
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:hla03000]
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Hlac_2629 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_3287 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_1523 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_3413 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_2818 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_1179 transcriptional regulator, AsnC family K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D Hlac_0889 transcriptional regulator, AsnC family K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D Hlac_2861 transcriptional regulator, IclR family K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
D Hlac_3665 transcriptional regulator, IclR family K21827 arcR; IclR family transcriptional regulator, arginine deiminase pathway regulator
D Hlac_1245 transcriptional regulator, ArsR family K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D Hlac_3139 transcriptional regulator, PadR-like family K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D Hlac_3443 transcriptional regulator, ArsR family K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D Hlac_1852 transcriptional regulator, ArsR family K07721 K07721; ArsR family transcriptional regulator
D Hlac_0446 DNA binding protein K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D Hlac_0657 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D Hlac_0171 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D Hlac_1468 biotin/acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D Hlac_2275 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Hlac_2487 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Hlac_1532 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Hlac_0543 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Hlac_1076 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Hlac_2683 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D Hlac_3482 putative PAS/PAC sensor protein K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D Hlac_1305 Bacterio-opsin activator HTH domain protein K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D Hlac_2080 Bacterio-opsin activator HTH domain protein K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D Hlac_2543 DNA binding protein, Tfx family K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator
D Hlac_0798 phosphoribosyltransferase K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D Hlac_2058 putative transcriptional regulator, ModE family K02019 modE; molybdate transport system regulatory protein
D Hlac_0273 transcriptional regulator, XRE family K07728 K07728; putative transcriptional regulator
D Hlac_0023 regulatory protein Crp K07730 K07730; putative transcriptional regulator
D Hlac_1971 transcriptional regulator, XRE family K07731 K07731; putative transcriptional regulator
D Hlac_2067 putative transcriptional regulator, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D Hlac_3543 putative transcriptional regulator, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D Hlac_2986 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D Hlac_2987 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D Hlac_2946 ATP-cone domain protein K07738 nrdR; transcriptional repressor NrdR
C 03021 Transcription machinery [BR:hla03021]
D Hlac_1327 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_0072 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_1495 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_1513 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_2880 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_0601 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_0309 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_3140 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_3420 Transcription factor TFIIB cyclin-related K03124 TFIIB; transcription initiation factor TFIIB
D Hlac_2629 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_3287 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_1523 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_3413 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_2818 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D Hlac_1708 Transcription factor TFIIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D Hlac_1535 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D Hlac_0816 helicase c2 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_2627 DEAD_2 domain protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_2395 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4
D Hlac_0899 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5
D Hlac_0103 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA
D Hlac_0105 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D Hlac_0104 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D Hlac_0106 RNA polymerase Rpb2 domain 6 K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D Hlac_0107 RNA polymerase beta subunit K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D Hlac_1819 RNA polymerase insert K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D Hlac_2396 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D Hlac_2278 RNA polymerase Rpb4 K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D Hlac_0108 RNA polymerase Rpb5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D Hlac_1824 RNA polymerase Rpb6 K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D Hlac_0620 RNA polymerase dimerisation K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D Hlac_1823 RNA polymerase, N/8 Kd subunit K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D Hlac_0565 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D Hlac_0970 Transcription factor TFIIS K03057 tfs; transcription factor S
D Hlac_1998 transcription termination factor Tfs K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:hla03019]
D Hlac_2395 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4
D Hlac_0899 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5
D Hlac_1716 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_2377 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_2030 translation factor pelota K06965 PELO; protein pelota
D Hlac_0170 eRF1 domain 2 protein K03265 ETF1; peptide chain release factor subunit 1
D Hlac_0156 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Hlac_0070 protein synthesis factor GTP-binding K03231 EEF1A; elongation factor 1-alpha
D Hlac_2047 beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D Hlac_0359 ribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1]
D Hlac_1825 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Hlac_0682 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Hlac_0056 DEAD/DEAH box helicase domain protein K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C 03041 Spliceosome
C 03011 Ribosome [BR:hla03011]
D Hlac_0618 ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D Hlac_2437 Ribosomal protein S4E, central domain protein K02987 RP-S4e; small subunit ribosomal protein S4e
D Hlac_2128 Ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D Hlac_1967 ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D Hlac_2338 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D Hlac_2312 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D Hlac_2393 Ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D Hlac_1010 Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D Hlac_1843 Ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D Hlac_2448 ribosomal protein L4/L1e K02930 RP-L4e; large subunit ribosomal protein L4e
D Hlac_1842 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Hlac_0057 ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D Hlac_0413 Ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D Hlac_1820 ribosomal protein L15 K02883 RP-L18e; large subunit ribosomal protein L18e
D Hlac_2431 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D Hlac_2277 Ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D Hlac_1844 Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D Hlac_0827 Ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D Hlac_2432 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D Hlac_2045 Ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D Hlac_0564 Ribosomal L37ae protein K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D Hlac_0828 Ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D Hlac_0373 Ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D Hlac_1011 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D Hlac_1826 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D Hlac_2443 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D Hlac_1817 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D Hlac_2429 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D Hlac_0100 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D Hlac_2434 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D Hlac_1822 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D Hlac_0157 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D Hlac_1818 ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D Hlac_0101 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12
D Hlac_1816 ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D Hlac_2435 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D Hlac_0615 Ribosomal S13S15 domain protein K02956 RP-S15; small subunit ribosomal protein S15
D Hlac_2440 ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D Hlac_2445 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D Hlac_2535 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D Hlac_2446 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D Hlac_2449 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D Hlac_2436 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D Hlac_2433 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D Hlac_2534 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D Hlac_1983 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D Hlac_1821 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D Hlac_2439 ribosomal protein L14b/L23e K02874 RP-L14; large subunit ribosomal protein L14
D Hlac_2427 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D Hlac_2430 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18
D Hlac_2444 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D Hlac_2447 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23
D Hlac_2438 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D Hlac_2442 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D Hlac_2428 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30
D Hlac_2533 ribosomal protein 60S K02869 RP-L12; large subunit ribosomal protein L12
D Hlac_0823 Ribosomal LX protein K02944 RP-LX; large subunit ribosomal protein LX
D Hlac_R0004 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0028 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0061 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0031 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0058 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0003 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0029 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0060 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:hla03009]
D Hlac_1041 Pre-mRNA processing ribonucleoprotein, binding domain protein K14564 NOP56; nucleolar protein 56
D Hlac_1008 RNA-binding protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Hlac_2661 KH type 1 domain protein K06961 KRR1; ribosomal RNA assembly protein
D Hlac_2660 protein of unknown function RIO1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D Hlac_0533 protein of unknown function RIO1 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D Hlac_1343 nucleotide kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D Hlac_1678 Protein of unknown function DUF367 K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D Hlac_0397 ABC transporter related K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D Hlac_2297 GTP-binding protein HSR1-related K06943 NOG1; nucleolar GTP-binding protein
D Hlac_2441 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Hlac_0962 Ribonuclease P-related K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Hlac_0960 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Hlac_0826 translation initiation factor eIF-6 K03264 EIF6; translation initiation factor 6
D Hlac_2215 NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3
D Hlac_0849 Shwachman-Bodian-Diamond syndrome protein K14574 SDO1; ribosome maturation protein SDO1
D Hlac_1716 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_2377 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_2746 GTP-binding protein HSR1-related K03595 era; GTPase
D Hlac_1042 fibrillarin K04795 flpA; fibrillarin-like pre-rRNA processing protein
D Hlac_1842 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D Hlac_0716 H/ACA RNA-protein complex component Gar1 K07569 gar1; RNA-binding protein
D Hlac_0103 NusA family KH domain protein K02600 nusA; transcription termination/antitermination protein NusA
D Hlac_2104 dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D Hlac_0434 ribosomal RNA methyltransferase RrmJ/FtsJ K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D Hlac_2685 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Hlac_2184 GCN5-related N-acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D Hlac_2369 RimK domain protein ATP-grasp K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D Hlac_2036 protein of unknown function DUF181 K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor
D Hlac_1303 GTP-binding proten HflX K03665 hflX; GTPase
D Hlac_0404 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Hlac_1188 protein of unknown function UPF0044 K07574 yhbY; RNA-binding protein
D Hlac_0779 GTPase of unknown function domain protein K06942 ychF; ribosome-binding ATPase
D Hlac_1465 GTPase of unknown function domain protein K06942 ychF; ribosome-binding ATPase
D Hlac_0040 protein of unknown function DUF402 K22469 fau-1; probable ribonuclease FAU-1 [EC:3.1.26.-]
C 03016 Transfer RNA biogenesis [BR:hla03016]
D Hlac_2441 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Hlac_0962 Ribonuclease P-related K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Hlac_0960 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Hlac_0943 RNAse P, Rpr2/Rpp21 subunit K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D Hlac_0076 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Hlac_2024 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D Hlac_2022 protein of unknown function DUF101 K24956 ZBTB8OS; protein archease
D Hlac_0156 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Hlac_0070 protein synthesis factor GTP-binding K03231 EEF1A; elongation factor 1-alpha
D Hlac_2322 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hlac_0777 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Hlac_0887 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Hlac_0366 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Hlac_0447 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Hlac_0169 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Hlac_2498 Threonyl/alanyl tRNA synthetase SAD K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hlac_0719 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Hlac_0293 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Hlac_1764 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Hlac_2073 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Hlac_0291 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Hlac_0018 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Hlac_2219 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Hlac_2671 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Hlac_2670 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Hlac_2505 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Hlac_1863 aminoacyl-tRNA synthetase class Ib K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Hlac_0902 Protein of unknown function DUF516 K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Hlac_0971 Threonyl/alanyl tRNA synthetase SAD K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D Hlac_0075 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Hlac_2210 MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D Hlac_2358 N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D Hlac_0733 protein of unknown function Met10 K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Hlac_1391 Methyltransferase type 12 K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D Hlac_1030 Methyltransferase type 11 K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D Hlac_1665 tRNA pseudouridine synthase K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Hlac_1812 pseudouridylate synthase TruB domain protein K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D Hlac_0572 tRNA pseudouridine synthase D TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D Hlac_1937 conserved hypothetical protein K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D Hlac_1480 histone acetyltransferase, ELP3 family K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D Hlac_0404 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Hlac_0336 tRNA nucleotidyltransferase, substrate binding domain protein K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D Hlac_2070 tRNA intron endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D Hlac_2724 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D Hlac_2387 lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D Hlac_1657 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D Hlac_1382 RNA methyltransferase, TrmH family, group 1 K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D Hlac_1588 protein of unknown function DUF358 K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D Hlac_2630 putative RNA methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D Hlac_1701 protein of unknown function DUF127 K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D Hlac_1485 RNA methylase, NOL1/NOP2/sun family K22446 K22446; tRNA (cytosine49-C5)-methyltransferase [EC:2.1.1.-]
D Hlac_2416 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Hlac_2421 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D Hlac_2494 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D Hlac_2392 metalloendopeptidase, glycoprotease family K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D Hlac_2703 Protein of unknown function DUF509 K09119 cgi121; KEOPS complex subunit Cgi121
D Hlac_0566 rpo operon protein K09741 pcc1; KEOPS complex subunit Pcc1
D Hlac_3292 ExsB family protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Hlac_3059 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Hlac_0517 conserved hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Hlac_3057 6-pyruvoyl tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Hlac_3058 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D Hlac_2160 tRNA-guanine transglycosylase, various specificities K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D Hlac_0272 domain of unknown function DUF1743 K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D Hlac_2320 protein of unknown function DUF699 ATPase putative K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D Hlac_0359 ribonuclease II K12573 rnr; ribonuclease R [EC:3.1.13.1]
C 03012 Translation factors [BR:hla03012]
D Hlac_1849 S1 IF1 family protein K03236 EIF1A; translation initiation factor 1A
D Hlac_2368 translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A
D Hlac_2078 translation initiation factor SUI1 K03113 EIF1; translation initiation factor 1
D Hlac_1009 translation initiation factor 2, alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
D Hlac_0818 Translation initiation factor IF2/IF5 K03238 EIF2S2; translation initiation factor 2 subunit 2
D Hlac_2398 protein synthesis factor GTP-binding K03242 EIF2S3; translation initiation factor 2 subunit 3
D Hlac_2279 initiation factor 2B related K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
D Hlac_1578 translation initiation factor eIF-5A K03263 EIF5A; translation initiation factor 5A
D Hlac_2060 translation initiation factor aIF-2 K03243 EIF5B; translation initiation factor 5B
D Hlac_0826 translation initiation factor eIF-6 K03264 EIF6; translation initiation factor 6
D Hlac_0156 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Hlac_0070 protein synthesis factor GTP-binding K03231 EEF1A; elongation factor 1-alpha
D Hlac_2341 translation elongation factor aEF-1 beta K03232 EEF1B; elongation factor 1-beta
D Hlac_0152 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D Hlac_0813 diphthamide biosynthesis protein K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D Hlac_0801 ATP binding protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D Hlac_0170 eRF1 domain 2 protein K03265 ETF1; peptide chain release factor subunit 1
D Hlac_2106 methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D Hlac_0573 protein of unknown function UPF0099 K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:hla03110]
D Hlac_0682 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Hlac_2662 thermosome K22447 cct; archaeal chaperonin
D Hlac_0416 thermosome K22447 cct; archaeal chaperonin
D Hlac_2284 chaperonin Cpn60/TCP-1 K22447 cct; archaeal chaperonin
D Hlac_0681 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D Hlac_1291 GrpE protein K03687 GRPE; molecular chaperone GrpE
D Hlac_0344 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D Hlac_0345 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D Hlac_0637 HSP20 type chaperone K13993 HSP20; HSP20 family protein
D Hlac_2370 HSP20 type chaperone K13993 HSP20; HSP20 family protein
D Hlac_2381 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D Hlac_0822 prefoldin, alpha subunit K04797 pfdA; prefoldin alpha subunit
D Hlac_0567 prefoldin, beta subunit K04798 pfdB; prefoldin beta subunit
D Hlac_2196 peptidase S8 and S53 subtilisin kexin sedolisin K01342 aprE; subtilisin [EC:3.4.21.62]
D Hlac_1668 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D Hlac_0806 peptidylprolyl isomerase FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D Hlac_0239 thioredoxin K03671 TXN; thioredoxin
D Hlac_2305 thioredoxin K03671 TXN; thioredoxin
D Hlac_0372 Thioredoxin domain protein K03671 TXN; thioredoxin
D Hlac_2342 Thioredoxin domain protein K03671 TXN; thioredoxin
D Hlac_0799 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin
C 04131 Membrane trafficking [BR:hla04131]
D Hlac_1845 nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D Hlac_1716 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_2377 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_1965 conserved hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D Hlac_3445 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_0661 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_1224 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_2712 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_0900 protein translocase SEC61 complex, gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Hlac_2371 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Hlac_0562 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Hlac_0156 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Hlac_0070 protein synthesis factor GTP-binding K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:hla04121]
D Hlac_0373 Ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 03051 Proteasome [BR:hla03051]
D Hlac_0963 20S proteasome A and B subunits K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Hlac_2172 20S proteasome A and B subunits K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D Hlac_0608 20S proteasome A and B subunits K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Hlac_1448 20S proteasome A and B subunits K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D Hlac_0185 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D Hlac_2011 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:hla03032]
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Hlac_0307 ribonuclease H K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Hlac_2653 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D Hlac_1698 DNA replication factor Dna2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D Hlac_1613 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Hlac_1008 RNA-binding protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D Hlac_2572 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D Hlac_2135 TOPRIM domain protein K02316 dnaG; DNA primase [EC:2.7.7.101]
D Hlac_0001 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_2631 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_2833 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_3320 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_1524 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_1078 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_1085 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_3641 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_2747 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_3539 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_3512 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_2958 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_2997 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_3367 orc1/cdc6 family replication initiation protein K10725 cdc6A; archaeal cell division control protein 6
D Hlac_2510 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Hlac_0740 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D Hlac_1798 DNA primase, small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D Hlac_2529 DNA primase, large subunit K18882 priL; DNA primase large subunit
D Hlac_1797 conserved hypothetical protein K09723 ginS; DNA replication factor GINS
D Hlac_1966 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Hlac_2645 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Hlac_0177 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Hlac_3264 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D Hlac_0150 DNA polymerase II, large subunit DP2 K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D Hlac_0003 metallophosphoesterase K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D Hlac_1810 AAA ATPase central domain protein K04800 rfcL; replication factor C large subunit
D Hlac_0384 Replication factor C K04801 rfcS; replication factor C small subunit
D Hlac_2519 AAA ATPase central domain protein K04801 rfcS; replication factor C small subunit
D Hlac_1929 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3321 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3349 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_0994 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D Hlac_0995 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D Hlac_1315 Spo11/DNA topoisomerase VI subunit A domain protein K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D Hlac_1314 DNA topoisomerase VI, B subunit K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D Hlac_2506 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Hlac_0259 DNA topoisomerase type IA central domain protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:hla03036]
D Hlac_2450 Protein of unknown function DUF171 K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D Hlac_0110 Transcription factor CBF/NF-Y/histone domain protein K24450 hmf; DNA-binding protein
D Hlac_2572 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D Hlac_0536 Ferritin Dps family protein K04047 dps; starvation-inducible DNA-binding protein
D Hlac_0527 chromosome segregation protein SMC K03529 smc; chromosome segregation protein
D Hlac_0528 chromosome segregation and condensation protein ScpA K05896 scpA; segregation and condensation protein A
D Hlac_0523 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Hlac_0901 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Hlac_0595 Cobyrinic acid ac-diamide synthase K03609 minD; septum site-determining protein MinD
D Hlac_0274 Cobyrinic acid ac-diamide synthase K03609 minD; septum site-determining protein MinD
D Hlac_0809 cell division inhibitor MinD-like (ATPase involved in chromosome partitioning) K03609 minD; septum site-determining protein MinD
D Hlac_2674 cell division inhibitor MinD-like (ATPase involved in chromosome partitioning) K03609 minD; septum site-determining protein MinD
D Hlac_3244 ParA family chromosome partitioning ATPase K03496 parA; chromosome partitioning protein
D Hlac_3382 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_2831 chromosome partitioning protein ParA K03496 parA; chromosome partitioning protein
D Hlac_3026 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_3098 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_3515 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_3588 integrase family protein K04763 xerD; integrase/recombinase XerD
D Hlac_2809 integrase family protein K04763 xerD; integrase/recombinase XerD
D Hlac_1341 protein of unknown function DUF59 K03593 mrp; ATP-binding protein involved in chromosome partitioning
D Hlac_1831 protein of unknown function DUF59 K03593 mrp; ATP-binding protein involved in chromosome partitioning
C 03400 DNA repair and recombination proteins [BR:hla03400]
D Hlac_1270 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D Hlac_0288 DNA photolyase FAD-binding K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Hlac_1437 DNA photolyase FAD-binding K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Hlac_2002 HhH-GPD family protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D Hlac_1517 8-oxoguanine DNA glycosylase domain protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D Hlac_0954 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Hlac_1044 HhH-GPD family protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D Hlac_2653 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D Hlac_1613 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Hlac_1535 type III restriction protein res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D Hlac_0816 helicase c2 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_2627 DEAD_2 domain protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D Hlac_0111 nucleic acid binding OB-fold tRNA/helicase-type K07466 RFA1; replication factor A1
D Hlac_0097 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Hlac_0379 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Hlac_1992 conserved hypothetical protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D Hlac_1742 HhH-GPD family protein K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D Hlac_0531 apurinic endonuclease Apn1 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D Hlac_0598 Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D Hlac_2552 phosphoesterase DHHA1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D Hlac_2645 DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Hlac_2607 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D Hlac_2638 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D Hlac_2725 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D Hlac_0203 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D Hlac_0119 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Hlac_2226 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Hlac_1501 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Hlac_2604 DNA mismatch repair protein MutS domain protein K07456 mutS2; DNA mismatch repair protein MutS2
D Hlac_2227 MutL dimerisation K03572 mutL; DNA mismatch repair protein MutL
D Hlac_0629 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Hlac_1929 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3321 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3349 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_0181 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
D Hlac_2789 SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
D Hlac_1592 AAA ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
D Hlac_0182 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D Hlac_3129 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D Hlac_2790 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D Hlac_3236 metallophosphoesterase K03547 sbcD; DNA repair protein SbcD/Mre11
D Hlac_2343 ATP-dependent exoDNAse (exonuclease V) beta subunit-like protein (contains helicase and exonuclease domains) K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Hlac_3200 UvrD/REP helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Hlac_2344 hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Hlac_3327 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Hlac_3578 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Hlac_2624 DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D Hlac_1629 DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
D Hlac_2659 Resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D Hlac_2702 DEAD/DEAH box helicase domain protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D Hlac_1207 DEAD/DEAH box helicase domain protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D Hlac_0994 DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D Hlac_0995 DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D Hlac_2506 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Hlac_0259 DNA topoisomerase type IA central domain protein K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D Hlac_2572 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D Hlac_2466 UMUC domain protein DNA-repair protein K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D Hlac_0442 PHP domain protein K02347 polX; DNA polymerase (family X)
D Hlac_1253 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Hlac_0265 DEAD/DEAH box helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D Hlac_2375 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Hlac_2944 ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Hlac_2945 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Hlac_0310 Protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:hla03029]
D Hlac_2441 Ribonuclease P, Rpp29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D Hlac_0962 Ribonuclease P-related K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D Hlac_0960 RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D Hlac_2746 GTP-binding protein HSR1-related K03595 era; GTPase
D Hlac_2505 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Hlac_0366 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Hlac_0293 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Hlac_0169 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Hlac_0835 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D Hlac_0431 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D Hlac_0834 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D Hlac_0682 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Hlac_1291 GrpE protein K03687 GRPE; molecular chaperone GrpE
D Hlac_0681 chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D Hlac_0799 glutaredoxin-like protein K07390 grxD; monothiol glutaredoxin
D Hlac_1341 protein of unknown function DUF59 K03593 mrp; ATP-binding protein involved in chromosome partitioning
D Hlac_1831 protein of unknown function DUF59 K03593 mrp; ATP-binding protein involved in chromosome partitioning
D Hlac_2407 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_2852 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D Hlac_1803 cytochrome oxidase assembly K02259 COX15; heme a synthase [EC:1.17.99.9]
D Hlac_1728 conserved hypothetical protein K07152 SCO1; protein SCO1
D Hlac_1631 electron transport protein SCO1/SenC K07152 SCO1; protein SCO1
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:hla02000]
D Hlac_0078 ABC transporter related K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D Hlac_0913 ABC transporter related K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D Hlac_1225 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D Hlac_1226 NifC-like ABC-type porter K15496 wtpB; molybdate/tungstate transport system permease protein
D Hlac_1227 ABC transporter related K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D Hlac_2057 molybdate transport protein K05772 tupA; tungstate transport system substrate-binding protein
D Hlac_3454 molybdate transport protein K05772 tupA; tungstate transport system substrate-binding protein
D Hlac_2056 binding-protein-dependent transport systems inner membrane component K05773 tupB; tungstate transport system permease protein
D Hlac_3453 binding-protein-dependent transport systems inner membrane component K05773 tupB; tungstate transport system permease protein
D Hlac_2055 ABC transporter related K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D Hlac_3452 ABC transporter related K06857 tupC; tungstate transport system ATP-binding protein [EC:7.3.2.6]
D Hlac_2149 ABC-type nitrate/sulfonate/bicarbonate transport systems protein K15553 ssuA; sulfonate transport system substrate-binding protein
D Hlac_2148 binding-protein-dependent transport systems inner membrane component K15554 ssuC; sulfonate transport system permease protein
D Hlac_2147 ABC transporter related K15555 ssuB; sulfonate transport system ATP-binding protein [EC:7.6.2.14]
D Hlac_0162 ABC-type iron(III) transport system,substrate-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D Hlac_0167 binding-protein-dependent transport systems inner membrane component K02011 afuB; iron(III) transport system permease protein
D Hlac_0472 ABC transporter related K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D Hlac_2697 ABC transporter, periplasmic binding protein, thiB subfamily K02064 thiB; thiamine transport system substrate-binding protein
D Hlac_2696 binding-protein-dependent transport systems inner membrane component K02063 thiP; thiamine transport system permease protein
D Hlac_2695 ABC transporter related K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D Hlac_2486 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_2523 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_0633 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_2865 ABC transporter related K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D Hlac_0632 extracellular solute-binding protein family 1 K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D Hlac_0631 binding-protein-dependent transport systems inner membrane component K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Hlac_0630 binding-protein-dependent transport systems inner membrane component K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D Hlac_2520 extracellular solute-binding protein family 1 K17315 gtsA; glucose/mannose transport system substrate-binding protein
D Hlac_2521 binding-protein-dependent transport systems inner membrane component K17316 gtsB; glucose/mannose transport system permease protein
D Hlac_2522 binding-protein-dependent transport systems inner membrane component K17317 gtsC; glucose/mannose transport system permease protein
D Hlac_2482 extracellular solute-binding protein family 1 K10236 thuE; trehalose/maltose transport system substrate-binding protein
D Hlac_2484 binding-protein-dependent transport systems inner membrane component K10237 thuF; trehalose/maltose transport system permease protein
D Hlac_2485 binding-protein-dependent transport systems inner membrane component K10238 thuG; trehalose/maltose transport system permease protein
D Hlac_2862 extracellular solute-binding protein family 1 K10188 lacE; lactose/L-arabinose transport system substrate-binding protein
D Hlac_2863 binding-protein-dependent transport systems inner membrane component K10189 lacF; lactose/L-arabinose transport system permease protein
D Hlac_2864 binding-protein-dependent transport systems inner membrane component K10190 lacG; lactose/L-arabinose transport system permease protein
D Hlac_1417 basic membrane lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D Hlac_1415 inner-membrane translocator K23535 nupB; general nucleoside transport system permease protein
D Hlac_1414 inner-membrane translocator K23536 nupC; general nucleoside transport system permease protein
D Hlac_1416 ABC transporter related K23537 nupA; general nucleoside transport system ATP-binding protein
D Hlac_2982 trehalose/maltose binding protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D Hlac_3551 ABC-type phosphate transport system, substrate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Hlac_0502 phosphate binding protein K02040 pstS; phosphate transport system substrate-binding protein
D Hlac_3552 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein
D Hlac_0503 phosphate ABC transporter, inner membrane subunit PstC K02037 pstC; phosphate transport system permease protein
D Hlac_3553 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein
D Hlac_0504 phosphate ABC transporter, inner membrane subunit PstA K02038 pstA; phosphate transport system permease protein
D Hlac_3554 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Hlac_0505 phosphate ABC transporter, ATPase subunit K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D Hlac_0378 phosphate/phosphonate ABC transporter periplasmic substrate-binding protein K02044 phnD; phosphonate transport system substrate-binding protein
D Hlac_0376 phosphonate ABC transporter, inner membrane subunit K02042 phnE; phosphonate transport system permease protein
D Hlac_0377 ABC transporter related K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D Hlac_0229 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_1149 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_1092 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D Hlac_0228 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_1091 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_1148 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_2918 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_2098 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D Hlac_0227 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_1090 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_2097 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_2919 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_1147 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D Hlac_0226 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_1146 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_2916 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_2096 ABC transporter related K01995 livG; branched-chain amino acid transport system ATP-binding protein
D Hlac_1145 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_0225 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2095 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_2917 ABC transporter related K01996 livF; branched-chain amino acid transport system ATP-binding protein
D Hlac_1804 extracellular solute-binding protein family 3 K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D Hlac_1805 polar amino acid ABC transporter, inner membrane subunit K02029 ABC.PA.P; polar amino acid transport system permease protein
D Hlac_1807 polar amino acid ABC transporter, inner membrane subunit K02029 ABC.PA.P; polar amino acid transport system permease protein
D Hlac_1806 ABC transporter related K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
D Hlac_0069 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0244 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0252 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_3666 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0133 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0674 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D Hlac_0068 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0245 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0251 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_3265 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0675 binding-protein-dependent transport systems inner membrane component K02033 ABC.PE.P; peptide/nickel transport system permease protein
D Hlac_0067 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_0250 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_3266 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_0246 binding-protein-dependent transport systems inner membrane component K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D Hlac_0066 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0243 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0249 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_3267 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0677 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D Hlac_0248 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D Hlac_0602 iron/cobalamin ABC transporter periplasmic substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D Hlac_0539 transport system permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D Hlac_0540 ABC transporter related K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D Hlac_0880 periplasmic binding protein K25034 btuF; cobalamin transport system substrate-binding protein
D Hlac_0881 transport system permease protein K25027 btuC; cobalamin transport system permease protein
D Hlac_0882 ABC transporter related K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]
D Hlac_1191 periplasmic solute binding protein K09815 znuA; zinc transport system substrate-binding protein
D Hlac_0851 periplasmic solute binding protein K09815 znuA; zinc transport system substrate-binding protein
D Hlac_1193 ABC-3 protein K09816 znuB; zinc transport system permease protein
D Hlac_0853 ABC-3 protein K09816 znuB; zinc transport system permease protein
D Hlac_1192 ABC transporter related K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Hlac_0852 ABC transporter related K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D Hlac_0498 BioY protein K03523 bioY; biotin transport system substrate-specific component
D Hlac_0500 cobalt transport protein K16783 bioN; biotin transport system permease protein
D Hlac_0499 ABC transporter related K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D Hlac_1161 ABC-type transport system involved in multi-copper enzyme maturation permease component K19341 nosY; Cu-processing system permease protein
D Hlac_1724 copper ABC transporter permease K19341 nosY; Cu-processing system permease protein
D Hlac_1722 copper-binding protein K07218 nosD; nitrous oxidase accessory protein
D Hlac_1723 ABC transporter related K19340 nosF; Cu-processing system ATP-binding protein
D Hlac_2643 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D Hlac_0327 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D Hlac_1429 ABC-type transport system permease protein 2 K01992 ABC-2.P; ABC-2 type transport system permease protein
D Hlac_2938 conserved hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D Hlac_1427 ABC transporter related K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Hlac_1162 ABC transporter related K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Hlac_2937 ABC transporter related K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Hlac_2644 ABC transporter related K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Hlac_0326 ABC transporter related K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Hlac_3159 ABC transporter related K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D Hlac_2169 protein of unknown function DUF214 K02004 ABC.CD.P; putative ABC transport system permease protein
D Hlac_2170 ABC transporter related K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D Hlac_0176 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D Hlac_1529 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D Hlac_2492 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D Hlac_0998 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D Hlac_2100 MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D Hlac_1924 major facilitator superfamily MFS_1 K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
D Hlac_1404 major facilitator superfamily MFS_1 K02575 NRT2; MFS transporter, NNP family, nitrate/nitrite transporter
D Hlac_1778 major facilitator superfamily MFS_1 K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
D Hlac_1455 major facilitator superfamily MFS_1 K19577 ydhP; MFS transporter, DHA1 family, inner membrane transport protein
D Hlac_2576 major facilitator superfamily MFS_1 K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D Hlac_1461 phosphoenolpyruvate-protein phosphotransferase K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
D Hlac_1462 phosphocarrier, HPr family K02784 ptsH; phosphocarrier protein HPr
D Hlac_1460 dihydroxyacetone kinase, phosphotransfer subunit K05881 dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121]
D Hlac_1993 TrkA-N domain protein K10716 kch; voltage-gated potassium channel
D Hlac_2623 Rh family protein/ammonium transporter K03320 amt; ammonium transporter, Amt family
D Hlac_1187 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel
D Hlac_2229 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel
D Hlac_1895 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel
D Hlac_1508 MscS Mechanosensitive ion channel K22044 ybiO; moderate conductance mechanosensitive channel
D Hlac_1828 hypothetical protein K22044 ybiO; moderate conductance mechanosensitive channel
D Hlac_2479 MscS Mechanosensitive ion channel K16052 ynaI; MscS family membrane protein
D Hlac_2606 MgtE integral membrane region K06213 mgtE; magnesium transporter
D Hlac_2738 MgtE integral membrane region K07244 K07244; mgtE-like transporter
D Hlac_2739 MgtE integral membrane region K07244 K07244; mgtE-like transporter
D Hlac_0338 Camphor resistance CrcB protein K06199 crcB; fluoride exporter
D Hlac_0339 Camphor resistance CrcB protein K06199 crcB; fluoride exporter
D Hlac_0407 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Hlac_2723 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Hlac_1889 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Hlac_1846 FG-GAP repeat protein K17713 bamB; outer membrane protein assembly factor BamB
D Hlac_0130 zinc/iron permease K07238 TC.ZIP; zinc transporter, ZIP family
D Hlac_1781 zinc/iron permease K07238 TC.ZIP; zinc transporter, ZIP family
D Hlac_0979 small multidrug resistance protein K11741 sugE; quaternary ammonium compound-resistance protein SugE
D Hlac_0999 protein of unknown function DUF6 transmembrane K08978 TC.BAT1; bacterial/archaeal transporter family protein
D Hlac_0208 L-lactate permease K03303 lutP; lactate permease
D Hlac_2669 L-lactate permease K03303 lutP; lactate permease
D Hlac_1055 BCCT transporter K05020 opuD; glycine betaine transporter
D Hlac_1901 sodium/calcium exchanger membrane region K07301 yrbG; cation:H+ antiporter
D Hlac_0903 Na+/Ca+ antiporter, CaCA family K07301 yrbG; cation:H+ antiporter
D Hlac_1799 Na+/Ca+ antiporter, CaCA family K07301 yrbG; cation:H+ antiporter
D Hlac_1308 Na+/solute symporter K14393 actP; cation/acetate symporter
D Hlac_2296 Na+/H+ antiporter NhaC K24446 arcD; arginine/ornithine antiporter
D Hlac_1955 sodium/hydrogen exchanger K24160 NHA1; sodium/hydrogen antiporter
D Hlac_2295 sodium/hydrogen exchanger K26730 napA; Na+:H+ antiporter
D Hlac_2691 conserved hypothetical protein K07228 khtT; K+:H+ antiporter subunit KhtT
D Hlac_0362 TrkA-C domain protein K07228 khtT; K+:H+ antiporter subunit KhtT
D Hlac_0363 sodium/hydrogen exchanger K26732 khtU; K+:H+ antiporter subunit KhtU
D Hlac_1184 cation transporter K03498 trkH; trk/ktr system potassium uptake protein
D Hlac_1185 cation transporter K03498 trkH; trk/ktr system potassium uptake protein
D Hlac_1186 TrkA-N domain protein K03499 trkA; trk/ktr system potassium uptake protein
D Hlac_0255 Xanthine/uracil/vitamin C permease K06901 pbuG; adenine/guanine/hypoxanthine permease
D Hlac_3445 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_0661 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_1224 Anion-transporting ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_2712 arsenite-activated ATPase ArsA K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D Hlac_3442 arsenical-resistance protein K03325 ACR3; arsenite transporter
D Hlac_0071 Bile acid:sodium symporter K03325 ACR3; arsenite transporter
D Hlac_0483 NADH/Ubiquinone/plastoquinone (complex I) K05565 mnhA; multicomponent Na+:H+ antiporter subunit A
D Hlac_0484 Na+/H+ antiporter MnhB subunit-related protein K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D Hlac_0841 pH adaptation potassium efflux system protein B1 (sodium-potassium/hydrogen antiporter subunit B1) K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D Hlac_0842 Na+/H+ antiporter MnhB subunit-related protein K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D Hlac_0485 NADH-ubiquinone oxidoreductase chain 4L K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D Hlac_0843 NADH-ubiquinone oxidoreductase chain 4L K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D Hlac_0486 NADH/Ubiquinone/plastoquinone (complex I) K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D Hlac_0844 NADH/Ubiquinone/plastoquinone (complex I) K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D Hlac_0845 NADH/Ubiquinone/plastoquinone (complex I) K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D Hlac_0846 NADH/Ubiquinone/plastoquinone (complex I) K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D Hlac_0487 cation antiporter K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D Hlac_0839 multiple resistance and pH regulation protein F K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D Hlac_0488 multiple resistance and pH regulation protein F K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D Hlac_0840 monovalent cation/proton antiporter, MnhG/PhaG subunit K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D Hlac_0489 monovalent cation/proton antiporter, MnhG/PhaG subunit K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D Hlac_1381 AzlC family protein K26605 azlC; branched chain amino acid efflux pump
D Hlac_1380 branched-chain amino acid transport K26606 azlD; branched chain amino acid efflux pump
D Hlac_0410 integral membrane protein-like protein K09125 yhhQ; queuosine precursor transporter
D Hlac_1965 conserved hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D Hlac_1633 cytochrome c biogenesis protein transmembrane region K06196 ccdA; cytochrome c-type biogenesis protein
D Hlac_1335 DMSO reductase family type II enzyme, molybdopterin subunit K00370 narG; nitrate reductase / nitrite oxidoreductase, alpha subunit [EC:1.7.5.1 1.7.99.-]
D Hlac_1336 DMSO reductase family type II enzyme, iron-sulfur subunit K00371 narH; nitrate reductase / nitrite oxidoreductase, beta subunit [EC:1.7.5.1 1.7.99.-]
D Hlac_1951 TspO and MBR like protein K05770 TSPO; translocator protein
C 02044 Secretion system [BR:hla02044]
D Hlac_2557 flagellin K07325 flaB; archaeal flagellin FlaB
D Hlac_0493 fla cluster protein FlaD K07327 flaD; archaeal flagellar protein FlaD
D Hlac_2564 Flagella accessory C family protein K23986 flaCE; archaeal flagellar protein FlaCE
D Hlac_2565 flagellin K07329 flaF; archaeal flagellar protein FlaF
D Hlac_2566 flagellin K07330 flaG; archaeal flagellar protein FlaG
D Hlac_2567 AAA ATPase K07331 flaH; archaeal flagellar protein FlaH
D Hlac_2568 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_1032 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_0978 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_3536 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_2569 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D Hlac_1031 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D Hlac_0977 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D Hlac_2136 peptidase A24A prepilin type IV K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D Hlac_1867 beta-lactamase domain protein K02238 comEC; competence protein ComEC
D Hlac_1964 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D Hlac_1963 SecD/SecF/SecDF export membrane protein K03074 secF; preprotein translocase subunit SecF
D Hlac_2426 preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D Hlac_0496 GTP-binding signal recognition particle SRP54 G-domain protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D Hlac_0821 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D Hlac_0900 protein translocase SEC61 complex, gamma subunit K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D Hlac_0717 Ribonucleoprotein complex SRP, Srp19 component K03105 SRP19; signal recognition particle subunit SRP19
D Hlac_0988 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D Hlac_2608 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
D Hlac_2609 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:hla02042]
D Hlac_0407 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Hlac_2723 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family
D Hlac_1889 protein of unknown function DUF21 K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:hla02022]
D Hlac_1519 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D Hlac_1809 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D Hlac_1908 multi-sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
D Hlac_2263 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Hlac_0694 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2561 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2262 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C 02035 Bacterial motility proteins [BR:hla02035]
D Hlac_2263 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D Hlac_2261 CheW protein K03408 cheW; purine-binding chemotaxis protein CheW
D Hlac_2562 CheC, inhibitor of MCP methylation K03410 cheC; chemotaxis protein CheC
D Hlac_2563 CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D Hlac_2264 MCP methyltransferase, CheR-type K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D Hlac_2262 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D Hlac_0694 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_2561 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D Hlac_1029 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_1681 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_0084 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2290 methyl-accepting chemotaxis sensory transducer K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_2726 methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor K03406 mcp; methyl-accepting chemotaxis protein
D Hlac_1861 methyl-accepting chemotaxis sensory transducer K06595 hemAT; heam-based aerotactic trancducer
D Hlac_2557 flagellin K07325 flaB; archaeal flagellin FlaB
D Hlac_0493 fla cluster protein FlaD K07327 flaD; archaeal flagellar protein FlaD
D Hlac_2564 Flagella accessory C family protein K23986 flaCE; archaeal flagellar protein FlaCE
D Hlac_2565 flagellin K07329 flaF; archaeal flagellar protein FlaF
D Hlac_2566 flagellin K07330 flaG; archaeal flagellar protein FlaG
D Hlac_2567 AAA ATPase K07331 flaH; archaeal flagellar protein FlaH
D Hlac_2568 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_1032 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_0978 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_3536 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D Hlac_2569 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D Hlac_1031 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D Hlac_0977 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D Hlac_2136 peptidase A24A prepilin type IV K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:hla04812]
D Hlac_0523 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Hlac_0901 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Hlac_0198 Tubulin/FtsZ GTPase K22222 cetZ; tubulin-like protein CetZ
D Hlac_1892 Tubulin/FtsZ GTPase K22222 cetZ; tubulin-like protein CetZ
D Hlac_0698 Tubulin/FtsZ GTPase K22222 cetZ; tubulin-like protein CetZ
D Hlac_0595 Cobyrinic acid ac-diamide synthase K03609 minD; septum site-determining protein MinD
D Hlac_0274 Cobyrinic acid ac-diamide synthase K03609 minD; septum site-determining protein MinD
D Hlac_0809 cell division inhibitor MinD-like (ATPase involved in chromosome partitioning) K03609 minD; septum site-determining protein MinD
D Hlac_2674 cell division inhibitor MinD-like (ATPase involved in chromosome partitioning) K03609 minD; septum site-determining protein MinD
D Hlac_3244 ParA family chromosome partitioning ATPase K03496 parA; chromosome partitioning protein
D Hlac_3382 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_2831 chromosome partitioning protein ParA K03496 parA; chromosome partitioning protein
D Hlac_3026 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_3098 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D Hlac_3515 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
C 04147 Exosome [BR:hla04147]
D Hlac_1825 enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D Hlac_2371 glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D Hlac_2372 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D Hlac_0562 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D Hlac_1668 peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D Hlac_0156 translation elongation factor EF-1, subunit alpha K03231 EEF1A; elongation factor 1-alpha
D Hlac_0070 protein synthesis factor GTP-binding K03231 EEF1A; elongation factor 1-alpha
D Hlac_0152 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D Hlac_0682 chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D Hlac_2287 phosphoglucose isomerase (PGI) K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D Hlac_1613 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Hlac_1209 inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Hlac_1766 IMP dehydrogenase/GMP reductase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D Hlac_1716 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_2377 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D Hlac_0075 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D Hlac_2212 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D Hlac_1006 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_3523 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0628 putative nonspecific lipid-transfer protein (sterol carrier protein) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D Hlac_0059 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D Hlac_1912 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D Hlac_0254 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Hlac_1118 phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D Hlac_2618 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D Hlac_2619 argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D Hlac_1546 Cys/Met metabolism pyridoxal-phosphate-dependent protein K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D Hlac_3269 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_1099 amidohydrolase K01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]
D Hlac_2458 Inositol phosphatase/fructose-16-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D Hlac_1122 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D Hlac_2374 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D Hlac_0015 delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D Hlac_1646 transcriptional coactivator/pterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D Hlac_2722 D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_0393 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D Hlac_0142 dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D Hlac_0386 Electron transfer flavoprotein alpha subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D Hlac_0802 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_1201 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D Hlac_0683 triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:hla02048]
D Hlac_3327 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Hlac_3578 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Hlac_3326 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2
D Hlac_3579 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2
D Hlac_3576 CRISPR-associated helicase, Cyano-type K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D Hlac_3329 putative helicase K07475 cas3; CRISPR-associated endonuclease Cas3-HD [EC:3.1.-.-]
D Hlac_0590 conserved hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Hlac_3328 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Hlac_3577 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D Hlac_3333 CRISPR-associated protein Cas6 K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D Hlac_3572 conserved hypothetical protein K19091 cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]
D Hlac_3331 CRISPR-associated protein, Csh2 family K19115 csh2; CRISPR-associated protein Csh2
D Hlac_3330 CRISPR-associated protein Cas5, Hmari subtype K19116 cas5h; CRISPR-associated protein Cas5h
D Hlac_3575 CRISPR-associated protein Csc1 K19120 csc1; CRISPR-associated protein Csc1
D Hlac_3574 CRISPR-associated protein Csc2 K19121 csc2; CRISPR-associated protein Csc2
D Hlac_3573 CRISPR-associated protein Csc3 K19122 csc3; CRISPR-associated protein Csc3
D Hlac_3519 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D Hlac_1929 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3321 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3349 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Hlac_3352 ATPase associated with various cellular activities AAA_5 K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]
D Hlac_3385 conserved hypothetical protein K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D Hlac_3255 transcriptional regulator, AbrB family K19156 prlF; antitoxin PrlF
D Hlac_3093 hypothetical protein K06218 relE; mRNA interferase RelE/StbE
D Hlac_0524 putative transcriptional regulator, CopG family K07746 parD1_3_4; antitoxin ParD1/3/4
D Hlac_0523 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Hlac_0901 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Hlac_2322 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Hlac_2062 conserved hypothetical protein K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C 04030 G protein-coupled receptors [BR:hla04030]
D Hlac_0574 rhodopsin K04642 hop; halorhodopsin
D Hlac_0085 rhodopsin K04643 sop; sensory rhodopsin
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:hla04090]
C 01504 Antimicrobial resistance genes [BR:hla01504]
D Hlac_1778 major facilitator superfamily MFS_1 K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:hla03100]
D Hlac_R0013 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0059 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0030 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0021 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D Hlac_R0010 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0056 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0022 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0039 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0045 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D Hlac_R0012 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D Hlac_R0008 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Hlac_R0009 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D Hlac_R0005 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D Hlac_R0057 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Hlac_R0015 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D Hlac_R0050 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Hlac_R0032 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D Hlac_R0023 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0047 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0052 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0037 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D Hlac_R0041 tRNA-His K14226 tRNA-His; tRNA His
D Hlac_R0026 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D Hlac_R0024 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0027 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0044 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0054 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0046 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D Hlac_R0040 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Hlac_R0055 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D Hlac_R0019 tRNA-Met K14230 tRNA-Met; tRNA Met
D Hlac_R0011 tRNA-Met K14230 tRNA-Met; tRNA Met
D Hlac_R0049 tRNA-Met K14230 tRNA-Met; tRNA Met
D Hlac_R0006 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Hlac_R0018 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D Hlac_R0034 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Hlac_R0007 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Hlac_R0042 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D Hlac_R0036 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0043 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0014 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0016 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D Hlac_R0048 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Hlac_R0017 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Hlac_R0033 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D Hlac_R0025 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D Hlac_R0038 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D Hlac_R0035 tRNA-Val K14237 tRNA-Val; tRNA Val
D Hlac_R0053 tRNA-Val K14237 tRNA-Val; tRNA Val
D Hlac_R0051 tRNA-Val K14237 tRNA-Val; tRNA Val
D Hlac_R0001 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0031 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0058 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D Hlac_R0003 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0029 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0060 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D Hlac_R0004 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0028 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0061 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D Hlac_R0020 ffs; SRP RNA; RNA component of signal recognition particle K01983 ffs; SRP RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D Hlac_1625 aldo/keto reductase K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D Hlac_0578 aldo/keto reductase K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D Hlac_0082 aldo/keto reductase K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D Hlac_1168 aldo/keto reductase K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D Hlac_2451 glucose sorbosone dehydrogenase K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]
D Hlac_1533 aldo/keto reductase K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D Hlac_2362 aldo/keto reductase K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D Hlac_0240 NADPH-dependent F420 reductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D Hlac_1638 FAD dependent oxidoreductase K00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]
D Hlac_1925 conserved hypothetical protein K18208 RNLS; renalase [EC:1.6.3.5]
D Hlac_3529 Alcohol dehydrogenase GroES domain protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D Hlac_1058 Alcohol dehydrogenase zinc-binding domain protein K00359 qorA; NADPH:quinone reductase [EC:1.6.5.5]
D Hlac_1256 pyridine nucleotide-disulphide oxidoreductase dimerisation region K17883 mtr; mycothione reductase [EC:1.8.1.15]
D Hlac_0830 peptide methionine sulfoxide reductase K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D Hlac_1317 methionine-R-sulfoxide reductase K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D Hlac_0634 glutathione S-transferase K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D Hlac_2979 glutathione S-transferase K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D Hlac_1049 multicopper oxidase type 2 K00421 lccA; laccase [EC:1.10.3.2]
D Hlac_1447 manganese containing catalase K07217 ydbD; manganese catalase [EC:1.11.1.6]
D Hlac_2050 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D Hlac_0989 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D Hlac_0405 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D Hlac_1677 alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D Hlac_2516 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D Hlac_2732 Brp-like protein protein-like protein K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]
D Hlac_0096 conserved hypothetical protein K20938 ladA; long-chain alkane monooxygenase [EC:1.14.14.28]
D Hlac_2847 mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D Hlac_2994 mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D Hlac_1221 Protein-tyrosine phosphatase, low molecular weight K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D Hlac_0507 Protein-tyrosine phosphatase, low molecular weight K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D Hlac_3558 Protein-tyrosine phosphatase, low molecular weight K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D Hlac_0342 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D Hlac_0343 protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D Hlac_0892 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D Hlac_2179 transferase hexapeptide repeat containing protein K00661 maa; maltose O-acetyltransferase [EC:2.3.1.79]
D Hlac_1067 glycosyl transferase group 1 K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-]
D Hlac_1997 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D Hlac_2634 NCAIR mutase (PurE)-related protein K06898 larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]
D Hlac_2157 PUA domain containing protein K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D Hlac_1373 Elongator protein 3/MiaB/NifB K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D Hlac_2117 PfkB domain protein K18478 yihV; sulfofructose kinase [EC:2.7.1.184]
D Hlac_1442 protein of unknown function DUF147 K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D Hlac_1265 UBA/THIF-type NAD/FAD binding protein K22837 ubaA; SAMP-activating enzyme [EC:2.7.7.100]
D Hlac_0421 UBA/THIF-type NAD/FAD binding protein K22837 ubaA; SAMP-activating enzyme [EC:2.7.7.100]
D Hlac_1342 CDP-alcohol phosphatidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D Hlac_0508 pyruvate phosphate dikinase PEP/pyruvate-binding K22579 rph; rifampicin phosphotransferase [EC:2.7.9.6]
D Hlac_2347 thioesterase superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D Hlac_0058 protein of unknown function DUF91 K07503 nucS; endonuclease [EC:3.1.-.-]
D Hlac_2605 endoribonuclease L-PSP K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D Hlac_0402 ATPase associated with various cellular activities AAA_3 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D Hlac_0585 ATPase associated with various cellular activities AAA_3 K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D Hlac_1036 protein of unknown function DUF62 K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D Hlac_1235 carbohydrate kinase, YjeF related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D Hlac_2603 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K06864 larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase [EC:4.4.1.37]
D Hlac_1654 protein of unknown function DUF111 K09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]
D Hlac_3044 Mur ligase family CapB protein K01932 capB; gamma-polyglutamate synthase [EC:6.3.2.-]
D Hlac_3663 hypothetical protein K01932 capB; gamma-polyglutamate synthase [EC:6.3.2.-]
D Hlac_3055 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D Hlac_1869 copper-translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D Hlac_0577 heavy metal translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D Hlac_2409 heavy metal translocating P-type ATPase K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D Hlac_2084 heavy metal translocating P-type ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
D Hlac_2668 protein of unknown function DUF162 K00782 lldG; L-lactate dehydrogenase complex protein LldG
C 99982 Energy metabolism
D Hlac_0016 conserved hypothetical protein K05337 fer; ferredoxin
D Hlac_3472 conserved hypothetical protein K05337 fer; ferredoxin
D Hlac_2247 SUF system FeS assembly protein, NifU family K04488 iscU; nitrogen fixation protein NifU and related proteins
D Hlac_1332 Rieske (2Fe-2S) domain protein K15878 K15878; rieske iron-sulfur protein
D Hlac_1333 Cytochrome b/b6 domain protein K15879 narC; cytochrome b-561
D Hlac_0387 Electron transfer flavoprotein alpha/beta-subunit K03521 fixA; electron transfer flavoprotein beta subunit
D Hlac_2497 protein of unknown function DUF1458 K09165 K09165; dodecin
D Hlac_1232 protein of unknown function DUF1458 K09165 K09165; dodecin
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D Hlac_1230 conserved hypothetical protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
C 99988 Secondary metabolism
C 99999 Others
D Hlac_1423 Glyoxalase/bleomycin resistance protein/dioxygenase K15975 K15975; glyoxalase family protein
D Hlac_1422 DoxX family protein K15977 K15977; putative oxidoreductase
D Hlac_2221 DoxX family protein K15977 K15977; putative oxidoreductase
D Hlac_0028 phospholipase/Carboxylesterase K06999 K06999; phospholipase/carboxylesterase
D Hlac_0811 phospholipase/Carboxylesterase K06999 K06999; phospholipase/carboxylesterase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D Hlac_0686 transcriptional regulator, XRE family K03627 MBF1; putative transcription factor
D Hlac_1312 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein
D Hlac_0048 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein
D Hlac_1630 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein
D Hlac_1986 cold-shock DNA-binding domain protein K03704 cspA; cold shock protein
D Hlac_2046 Like-Sm ribonucleoprotein core K04796 RUXX; small nuclear ribonucleoprotein
D Hlac_0957 conserved hypothetical protein K07743 K07743; transcriptional regulator
D Hlac_0936 Protein of unknown function DUF293 K07744 K07744; transcriptional regulator
C 99974 Translation
D Hlac_2103 Protein of unknown function DUF655 K07572 K07572; putative nucleotide binding protein
D Hlac_1796 beta-lactamase domain protein K07577 K07577; putative mRNA 3-end processing factor
D Hlac_3400 exonuclease of the beta-lactamase fold class-like protein K07577 K07577; putative mRNA 3-end processing factor
D Hlac_1492 methyltransferase small K07579 K07579; putative methylase
D Hlac_2340 Protein of unknown function DUF1610 K07580 K07580; Zn-ribbon RNA-binding protein
D Hlac_0947 Protein of unknown function DUF54 K07581 K07581; RNA-binding protein
D Hlac_2217 conserved hypothetical protein K07585 K07585; tRNA methyltransferase
C 99975 Protein processing
D Hlac_2499 AIR synthase related protein domain protein K04655 hypE; hydrogenase expression/formation protein HypE
D Hlac_0663 PUA domain containing protein K07398 K07398; conserved protein with predicted RNA binding PUA domain
D Hlac_2408 conserved hypothetical selenoprotein K07401 K07401; selenoprotein W-related protein
D Hlac_3449 conserved hypothetical selenoprotein K07401 K07401; selenoprotein W-related protein
C 99976 Replication and repair
D Hlac_2761 adenine-specific DNA methylase K07445 K07445; putative DNA methylase
D Hlac_3347 adenine-specific DNA methylase K07445 K07445; putative DNA methylase
D Hlac_2636 Excinuclease ABC C subunit domain protein K07461 K07461; putative endonuclease
D Hlac_3173 conserved hypothetical protein K06919 K06919; putative DNA primase/helicase
D Hlac_2929 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_1129 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_3227 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_3365 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_0415 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_0427 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_0437 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_2570 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_2871 transposase IS200-family protein K07491 rayT; REP-associated tyrosine transposase
D Hlac_0426 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2571 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3397 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_0436 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_1603 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_0365 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_0414 Protein of unknown function DUF1225 K07496 K07496; putative transposase
D Hlac_1128 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_0580 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3248 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3051 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2621 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2949 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2960 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2977 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3228 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2872 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3363 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3375 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_3391 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_2928 transposase, IS605 OrfB family K07496 K07496; putative transposase
D Hlac_1494 transposase K07498 K07498; putative transposase
D Hlac_1512 transposase K07498 K07498; putative transposase
D Hlac_3528 transposase K07498 K07498; putative transposase
D Hlac_3224 transposase K07498 K07498; putative transposase
C 99979 Viral proteins
C 99998 Others
D Hlac_1621 phage shock protein A, PspA K03969 pspA; phage shock protein A
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D Hlac_2299 formate/nitrite transporter K21990 yfdC; formate-nitrite transporter family protein
D Hlac_1014 formate/nitrite transporter K21990 yfdC; formate-nitrite transporter family protein
D Hlac_2687 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D Hlac_1266 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D Hlac_1905 amino acid permease-associated region K03294 TC.APA; basic amino acid/polyamine antiporter, APA family
D Hlac_0331 phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family
D Hlac_1999 phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family
D Hlac_1653 phosphate transporter K03306 TC.PIT; inorganic phosphate transporter, PiT family
D Hlac_2133 Na+/solute symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D Hlac_1637 sodium:neurotransmitter symporter K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
C 99978 Cell growth
D Hlac_0029 SpoVR family protein K06415 spoVR; stage V sporulation protein R
C 99993 Cell motility
D Hlac_2266 Protein of unknown function DUF439 K09156 cheF; taxis protein CheF
D Hlac_2175 Protein of unknown function DUF439 K09156 cheF; taxis protein CheF
D Hlac_2265 HEAT domain containing protein K22221 K22221; HEAT repeat-containing taxis protein
D Hlac_3311 Protein of unknown function DUF1628 K23255 pilA; archaeal type IV pilus assembly protein PilA
D Hlac_3589 Protein of unknown function DUF1628 K23255 pilA; archaeal type IV pilus assembly protein PilA
D Hlac_0390 conserved hypothetical protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D Hlac_1618 hypothetical protein K23255 pilA; archaeal type IV pilus assembly protein PilA
C 99995 Signaling proteins
D Hlac_2711 carbon starvation protein CstA K06200 cstA; carbon starvation protein
D Hlac_0032 putative serine protein kinase, PrkA K07180 prkA; serine protein kinase
D Hlac_1702 putative circadian clock protein, KaiC K08482 kaiC; circadian clock protein KaiC
D Hlac_2216 DNA-binding TFAR19-related protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
D Hlac_1511 hypothetical protein K26284 csg; S-layer glycoprotein
D Hlac_0412 hypothetical protein K26284 csg; S-layer glycoprotein
D Hlac_2976 hypothetical protein K26284 csg; S-layer glycoprotein
C 99994 Others
D Hlac_2346 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein
D Hlac_3555 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein
D Hlac_0506 phosphate uptake regulator, PhoU K02039 phoU; phosphate transport system protein
D Hlac_1163 periplasmic copper-binding K07218 nosD; nitrous oxidase accessory protein
D Hlac_1722 copper-binding protein K07218 nosD; nitrous oxidase accessory protein
D Hlac_2123 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D Hlac_1721 NosL family protein K19342 nosL; copper chaperone NosL
D Hlac_2891 protein of unknown function DUF1648 K26996 sdpI; immunity protein, SdpI family
B
B 09194 Poorly characterized
C 99996 General function prediction only
D Hlac_0722 PilT protein domain protein K06865 K06865; ATPase
D Hlac_3234 DEAD/DEAH box helicase domain protein K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D Hlac_1438 DEAD/DEAH box helicase domain protein K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D Hlac_1552 globin K06886 glbN; hemoglobin
D Hlac_1018 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 K07025; putative hydrolase of the HAD superfamily
D Hlac_0175 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D Hlac_0174 SufBD protein K09015 sufD; Fe-S cluster assembly protein SufD
D Hlac_2981 membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein
D Hlac_1449 membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein
D Hlac_0563 membrane-bound metal-dependent hydrolase K07038 K07038; inner membrane protein
D Hlac_1934 TatD-related deoxyribonuclease K07049 K07049; TatD-related deoxyribonuclease
D Hlac_0260 ribonuclease BN K07058 K07058; membrane protein
D Hlac_2359 ribonuclease BN K07058 K07058; membrane protein
D Hlac_1365 FxsA cytoplasmic membrane protein K07113 fxsA; UPF0716 protein FxsA
D Hlac_0335 HAD superfamily (subfamily IA) hydrolase, TIGR01548 K11777 K11777; HAD superfamily phosphatase
D Hlac_2453 conserved hypothetical protein K03975 dedA; membrane-associated protein
D Hlac_2339 protein of unknown function DUF112 transmembrane K08971 K08971; putative membrane protein
D Hlac_1061 protein of unknown function DUF368 K08974 K08974; putative membrane protein
D Hlac_0455 Protein of unknown function DUF373 K08975 K08975; putative membrane protein
D Hlac_0314 Protein of unknown function DUF373 K08975 K08975; putative membrane protein
D Hlac_0654 protein of unknown function DUF420 K08976 K08976; putative membrane protein
D Hlac_1474 protein of unknown function DUF420 K08976 K08976; putative membrane protein
D Hlac_1233 membrane protein-like protein K08979 K08979; putative membrane protein
D Hlac_1204 membrane-flanked domain protein K08981 K08981; putative membrane protein
D Hlac_3542 conserved hypothetical protein K08982 K08982; putative membrane protein
D Hlac_3020 conserved hypothetical protein K08982 K08982; putative membrane protein
D Hlac_3030 conserved hypothetical protein K08982 K08982; putative membrane protein
D Hlac_2993 conserved hypothetical protein K08982 K08982; putative membrane protein
D Hlac_1870 conserved hypothetical protein K08982 K08982; putative membrane protein
D Hlac_0727 hypothetical protein K06193 phnA; protein PhnA
C 99997 Function unknown
D Hlac_1531 protein of unknown function DUF75 K06869 K06869; uncharacterized protein
D Hlac_1486 protein of unknown function DUF75 K06869 K06869; uncharacterized protein
D Hlac_0316 DRTGG domain protein K06873 K06873; uncharacterized protein
D Hlac_1569 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein
D Hlac_0425 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein
D Hlac_1296 protein of unknown function DUF255 K06888 K06888; uncharacterized protein
D Hlac_2274 protein of unknown function DUF255 K06888 K06888; uncharacterized protein
D Hlac_2027 peptidase S15 K06889 K06889; uncharacterized protein
D Hlac_2804 ATPase K06921 K06921; uncharacterized protein
D Hlac_1762 CoA-binding domain protein K06929 K06929; uncharacterized protein
D Hlac_0149 protein of unknown function DUF296 K06934 K06934; uncharacterized protein
D Hlac_0557 protein of unknown function UPF0153 K06940 K06940; uncharacterized protein
D Hlac_1197 metal dependent phosphohydrolase K06950 K06950; uncharacterized protein
D Hlac_0625 metallophosphoesterase K06953 K06953; uncharacterized protein
D Hlac_2116 photosystem I assembly BtpA K06971 K06971; uncharacterized protein
D Hlac_0298 Succinylglutamate desuccinylase/aspartoacylase K06987 K06987; uncharacterized protein
D Hlac_1973 Succinylglutamate desuccinylase/aspartoacylase K06987 K06987; uncharacterized protein
D Hlac_1426 Succinylglutamate desuccinylase/aspartoacylase K06987 K06987; uncharacterized protein
D Hlac_1194 conserved hypothetical protein K07003 K07003; uncharacterized protein
D Hlac_3221 conserved hypothetical protein K07003 K07003; uncharacterized protein
D Hlac_0322 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 K07005; uncharacterized protein
D Hlac_1003 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 K07005; uncharacterized protein
D Hlac_0886 conserved hypothetical protein K07005 K07005; uncharacterized protein
D Hlac_2000 conserved hypothetical protein K07018 K07018; uncharacterized protein
D Hlac_0966 beta-lactamase domain protein K07041 K07041; uncharacterized protein
D Hlac_0780 amidohydrolase 2 K07045 K07045; uncharacterized protein
D Hlac_0729 amidohydrolase 2 K07045 K07045; uncharacterized protein
D Hlac_3193 PilT protein domain protein K07065 K07065; uncharacterized protein
D Hlac_1082 conserved hypothetical protein K07065 K07065; uncharacterized protein
D Hlac_1005 protein of unknown function DUF35 K07068 K07068; uncharacterized protein
D Hlac_3522 protein of unknown function DUF35 K07068 K07068; uncharacterized protein
D Hlac_0627 protein of unknown function DUF35 K07068 K07068; uncharacterized protein
D Hlac_2329 TRAP transporter solute receptor, TAXI family K07080 K07080; uncharacterized protein
D Hlac_3527 TRAP-type uncharacterized transport system periplasmic component-like protein K07080 K07080; uncharacterized protein
D Hlac_2586 TRAP transporter solute receptor, TAXI family K07080 K07080; uncharacterized protein
D Hlac_3019 permease K07089 K07089; uncharacterized protein
D Hlac_0285 protein of unknown function DUF81 K07090 K07090; uncharacterized protein
D Hlac_1793 protein of unknown function DUF81 K07090 K07090; uncharacterized protein
D Hlac_3036 protein of unknown function DUF81 K07090 K07090; uncharacterized protein
D Hlac_0983 protein of unknown function DUF839 K07093 K07093; uncharacterized protein
D Hlac_1906 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein
D Hlac_0329 phosphodiesterase, MJ0936 family K07095 K07095; uncharacterized protein
D Hlac_2163 conserved hypothetical protein K07097 K07097; uncharacterized protein
D Hlac_0430 phosphoribosyltransferase K07101 K07101; uncharacterized protein
D Hlac_2625 amino acid-binding ACT domain protein K07103 K07103; uncharacterized protein
D Hlac_1260 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein
D Hlac_1499 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein
D Hlac_1500 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein
D Hlac_2423 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein
D Hlac_2424 protein of unknown function DUF395 YeeE/YedE K07112 K07112; uncharacterized protein
D Hlac_0312 Radical SAM domain protein K07129 K07129; uncharacterized protein
D Hlac_2173 MOSC domain containing protein K07140 K07140; MOSC domain-containing protein
D Hlac_1538 protein of unknown function DUF405 K07148 K07148; uncharacterized protein
D Hlac_2397 PilT N-term./Vapc superfamily-like protein K07158 K07158; uncharacterized protein
D Hlac_1007 protein of unknown function DUF75 K07159 K07159; uncharacterized protein
D Hlac_2744 conserved hypothetical protein K07163 K07163; uncharacterized protein
D Hlac_0858 protein of unknown function DUF151 K08999 K08999; uncharacterized protein
D Hlac_1384 protein of unknown function DUF192 K09005 K09005; uncharacterized protein
D Hlac_2526 protein of unknown function DUF192 K09005 K09005; uncharacterized protein
D Hlac_0257 protein of unknown function DUF192 K09005 K09005; uncharacterized protein
D Hlac_0381 protein of unknown function DUF99 K09120 K09120; uncharacterized protein
D Hlac_0441 protein of unknown function DUF82 K09122 K09122; uncharacterized protein
D Hlac_2470 AMMECR1 domain protein K09141 K09141; uncharacterized protein
D Hlac_2689 Protein of unknown function DUF424 K09148 K09148; uncharacterized protein
D Hlac_2504 Protein of unknown function DUF460 K09150 K09150; uncharacterized protein
D Hlac_0118 Protein of unknown function DUF1621 K09152 K09152; uncharacterized protein
D Hlac_2337 protein of unknown function DUF447 K09154 K09154; uncharacterized protein
D Hlac_0666 metal dependent phosphohydrolase K09163 K09163; uncharacterized protein
D Hlac_1948 protein of unknown function DUF1684 K09164 K09164; uncharacterized protein
D Hlac_1972 protein of unknown function DUF1684 K09164 K09164; uncharacterized protein
D Hlac_1200 conserved hypothetical protein K09166 K09166; uncharacterized protein
D Hlac_1203 membrane-flanked domain protein K09167 K09167; uncharacterized protein
D Hlac_2102 Protein of unknown function YqcI/YcgG K09190 K09190; uncharacterized protein
D Hlac_0959 Protein of unknown function DUF357 K09728 K09728; uncharacterized protein
D Hlac_2319 Protein of unknown function UPF0179 K09730 K09730; uncharacterized protein
D Hlac_0869 Protein of unknown function DUF555 K09731 K09731; uncharacterized protein
D Hlac_1516 Protein of unknown function DUF555 K09731 K09731; uncharacterized protein
D Hlac_1856 Protein of unknown function DUF54 K09736 K09736; uncharacterized protein
D Hlac_0781 Protein of unknown function DUF371 K09738 K09738; uncharacterized protein
D Hlac_2745 conserved hypothetical protein K09743 K09743; uncharacterized protein
D Hlac_3082 protein of unknown function DUF790 K09744 K09744; uncharacterized protein
D Hlac_1481 protein of unknown function DUF790 K09744 K09744; uncharacterized protein
D Hlac_3186 protein of unknown function DUF790 K09744 K09744; uncharacterized protein
D Hlac_0137 conserved hypothetical protein K09746 K09746; uncharacterized protein
D Hlac_0624 conserved hypothetical protein K09746 K09746; uncharacterized protein
D Hlac_2598 protein of unknown function DUF309 K09763 K09763; uncharacterized protein
D Hlac_0030 protein of unknown function DUF444 K09786 K09786; uncharacterized protein
D Hlac_0944 protein of unknown function DUF343 K09791 K09791; uncharacterized protein
D Hlac_0576 conserved hypothetical protein K09792 K09792; uncharacterized protein
D Hlac_1727 conserved hypothetical protein K09792 K09792; uncharacterized protein
D Hlac_1932 protein of unknown function DUF456 K09793 K09793; uncharacterized protein
D Hlac_2298 protein of unknown function DUF541 K09807 K09807; uncharacterized protein
D Hlac_1827 conserved hypothetical protein K09940 K09940; uncharacterized protein
D Hlac_2527 protein of unknown function DUF1508 K09946 K09946; uncharacterized protein
D Hlac_1783 conserved hypothetical protein K07502 yprB; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 22, 2024