+C	Cytokine	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Cytokines and Neuropeptides - Haliaeetus leucocephalus (bald eagle)</h2>
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A<b>Cytokines</b>
B  Interleukins
C    104828915 interleukin-1 beta-like	K04519 IL1B; interleukin 1 beta 
C    104828865 interleukin-36 receptor antagonist protein-like isoform X1	K05481 IL1RN; interleukin 1 receptor antagonist 
C    104836857 interleukin-15-like	K05429 IL2; interleukin 2 
C    104838075 IL6; interleukin-6	K05405 IL6; interleukin 6 
C    104837056 uncharacterized protein LOC104837056	K05431 IL7; interleukin 7 
C    104839079 uncharacterized protein LOC104839079	K05432 IL9; interleukin 9 
C    104839037 IL10; interleukin-10	K05443 IL10; interleukin 10 
C    104842575 IL12A; interleukin-12 subunit alpha	K05406 IL12A; interleukin 12A 
C    104839011 IL12B; interleukin-12 subunit beta	K05425 IL12B; interleukin 12B 
C    104831392 IL15; interleukin-15	K05433 IL15; interleukin 15 
C    104834533 IL16; pro-interleukin-16	K22628 IL16; interleukin 16 
C    104841439 IL17A; interleukin-17A	K05489 IL17A; interleukin 17A 
C    104839001 IL17B; interleukin-17B	K05490 IL17B; interleukin 17B 
C    104839427 IL17C; interleukin-17C	K05491 IL17C; interleukin 17C 
C    104841440 interleukin-17F-like	K05494 IL17F; interleukin 17F 
C    104836409 IL18; interleukin-18 isoform X1	K05482 IL18; interleukin 18 
C    104839523 interleukin-20-like	K22667 IL20; interleukin 20 
C    104836858 IL21; interleukin-21	K05434 IL21; interleukin 21 
C    104828217 IL22; interleukin-22	K05445 IL22; interleukin 22 
C    104830350 IL23A; interleukin-23 subunit alpha	K05426 IL23A; interleukin 23 subunit alpha 
C    104828576 EBI3; interleukin-27 subunit beta	K24476 EBI3; interleukin 27 subunit beta 
C    104842004 IL34; interleukin-34	K22633 IL34; interleukin 34 
B  Interferons
C    104829915 interferon epsilon-like	K05414 IFNA; interferon alpha 
C    104838436 interferon omega-1-like	K05414 IFNA; interferon alpha 
C    104827847 interferon-like	K05415 IFNB; interferon beta 
C    104828216 IFNG; interferon gamma	K04687 IFNG; interferon gamma 
C    104838248 interferon lambda-3-like	K22669 IFNL2_3; interferon lambda 2/3 
B  CSF and other factors
C    104842446 CSF1; macrophage colony-stimulating factor 1	K05453 CSF1; macrophage colony-stimulating factor 1 
C    104842907 CSF3; granulocyte colony-stimulating factor	K05423 CSF3; granulocyte colony-stimulating factor 
C    104827962 somatotropin isoform X1	K05438 GH; growth hormone 
C    104835207 THPO; thrombopoietin	K06854 THPO; thrombopoietin 
C    104829244 LIF; leukemia inhibitory factor	K05419 LIF; leukemia inhibitory factor 
C    104832080 CNTF; ciliary neurotrophic factor	K05420 CNTF; ciliary neurotrophic factor 
B  Chemokines
C    104835536 regakine-1-like	K05514 CCL1; C-C motif chemokine 1 
C    104843159 C-C motif chemokine 4-like	K12964 CCL4; C-C motif chemokine 4 
C    104843161 C-C motif chemokine 4 homolog isoform X1	K12964 CCL4; C-C motif chemokine 4 
C    104843158 CCL5; C-C motif chemokine 5	K12499 CCL5; C-C motif chemokine 5 
C    104841628 CCL17; C-C motif chemokine 17	K21083 CCL17; C-C motif chemokine 17 
C    104829780 CCL19; C-C motif chemokine 19	K05512 CCL19; C-C motif chemokine 19 
C    104832238 CCL20; C-C motif chemokine 20	K14625 CCL20; C-C motif chemokine 20 
C    104829771 CCL21; C-C motif chemokine 21	K16062 CCL21; C-C motif chemokine 21 
C    104836756 interleukin-8	K10030 IL8; interleukin 8 
C    104836757 interleukin-8-like	K10030 IL8; interleukin 8 
C    104836831 interleukin-8-like	K10030 IL8; interleukin 8 
C    104836832 interleukin-8-like	K10030 IL8; interleukin 8 
C    104829311 CXCL12; stromal cell-derived factor 1	K10031 CXCL12; C-X-C motif chemokine 12 
C    104836843 CXCL13; C-X-C motif chemokine 13	K10032 CXCL13; C-X-C motif chemokine 13 
C    104836844 interleukin-8-like	K10032 CXCL13; C-X-C motif chemokine 13 
C    104836845 C-X-C motif chemokine 2-like	K10032 CXCL13; C-X-C motif chemokine 13 
C    104838863 CXCL14; C-X-C motif chemokine 14	K10033 CXCL14; C-X-C motif chemokine 14 
C    104842673 CX3CL1; fractalkine	K05508 CX3CL1; C-X3-C motif chemokine 1 
C    104831847 lymphotactin-like	K05507 XCL; C motif chemokine 
C    104835312 PROK2; prokineticin-2	K24191 PROK; prokineticin 
C    104842331 PROK1; prokineticin-1	K24191 PROK; prokineticin 
C    104841657 CYTL1; cytokine-like protein 1	K25418 CYTL1; cytokine-like protein 1 
B  Tumor necrosis fators
C    104834828 CD40LG; CD40 ligand	K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5 
C    104840355 FASLG; tumor necrosis factor ligand superfamily member 6	K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6 
C    104833964 tumor necrosis factor ligand superfamily member 8-like	K05471 TNFSF8; tumor necrosis factor ligand superfamily member 8 
C    104835094 TNFSF10; tumor necrosis factor ligand superfamily member 10	K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10 
C    104837359 TNFSF11; tumor necrosis factor ligand superfamily member 11	K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11 
C    104838540 TNFSF13B; tumor necrosis factor ligand superfamily member 13B	K05476 TNFSF13B; tumor necrosis factor ligand superfamily member 13B 
C    104832624 TNFSF14; tumor necrosis factor ligand superfamily member 14	K05477 TNFSF14; tumor necrosis factor ligand superfamily member 14 
C    104833965 TNFSF15; tumor necrosis factor ligand superfamily member 15	K05478 TNFSF15; tumor necrosis factor ligand superfamily member 15 
C    104834860 EDA; ectodysplasin-A	K05480 EDA; ectodysplasin-A 
B  Transforming growth factors (RSTK binding)
C    104828464 TGFB2; transforming growth factor beta-2	K13376 TGFB2; transforming growth factor beta-2 
C    104841819 TGFB3; transforming growth factor beta-3	K13377 TGFB3; transforming growth factor beta-3 
C    104828986 BMP1; bone morphogenetic protein 1	K05502 BMP1; bone morphogenetic protein 1 [EC:3.4.24.19] 
C    104829341 bone morphogenetic protein 7-like	K21283 BMP2; bone morphogenetic protein 2 
C    104836449 BMP2; bone morphogenetic protein 2	K21283 BMP2; bone morphogenetic protein 2 
C    104839877 bone morphogenetic protein 2-B-like	K21283 BMP2; bone morphogenetic protein 2 
C    104836825 BMP3; bone morphogenetic protein 3	K05496 BMP3; bone morphogenetic protein 3 
C    104839481 BMP4; bone morphogenetic protein 4	K04662 BMP4; bone morphogenetic protein 4 
C    104831053 BMP5; bone morphogenetic protein 5	K04663 BMP5; bone morphogenetic protein 5 
C    104835364 BMP6; bone morphogenetic protein 6	K16620 BMP6; bone morphogenetic protein 6 
C    104833203 BMP7; bone morphogenetic protein 7	K16621 BMP7; bone morphogenetic protein 7 
C    104837291 bone morphogenetic protein 8A-like	K16622 BMP8; bone morphogenetic protein 8 
C    104828889 BMP10; bone morphogenetic protein 10	K22670 BMP10; bone morphogenetic protein 10 
C    104831477 BMP15; bone morphogenetic protein 15	K05498 BMP15; bone morphogenetic protein 15 
C    104829137 GDF1; embryonic growth/differentiation factor 1	K05495 GDF1; growth differentiation factor 1 
C    104829320 GDF2; growth/differentiation factor 2	K05503 GDF2; growth differentiation factor 2 
C    104841981 GDF5; growth/differentiation factor 5	K04664 GDF5; growth differentiation factor 5 
C    104842163 GDF7; growth/differentiation factor 7	K20013 GDF7; growth differentiation factor 7 
C    104829529 MSTN; growth/differentiation factor 8 isoform X1	K05497 MSTN; growth differentiation factor 8 
C    104838838 GDF9; growth/differentiation factor 9	K22673 GDF9; growth differentiation factor 9 
C    104829344 GDF10; bone morphogenetic protein 3B	K22674 GDF10; growth differentiation factor 10 
C    104830335 GDF11; growth/differentiation factor 11	K22679 GDF11; growth differentiation factor 11 
C    104828555 GDF15; growth/differentiation factor 15	K05504 GDF15; growth differentiation factor 15 
C    104828966 NODAL; nodal homolog	K04666 NODAL; nodal 
C    104831941 INHA; inhibin alpha chain	K05500 INHA; inhibin, alpha 
C    104840669 INHBA; inhibin beta A chain	K04667 INHBA; inhibin beta A chain 
C    104833271 INHBB; inhibin beta B chain	K22687 INHBB; inhibin beta B chain 
C    104831202 AMH; muellerian-inhibiting factor	K04665 AMH; anti-mullerian hormone 
C    104838215 left-right determination factor 2-like	K04668 LEFTY; left-right determination factor 
B  Growth factors (RTK binding)
C    104833534 PDGFA; platelet-derived growth factor subunit A isoform X1	K04359 PDGFA; platelet-derived growth factor subunit A 
C    104830849 PDGFB; platelet-derived growth factor subunit B	K17386 PDGFB; platelet-derived growth factor subunit B 
C    104828445 PDGFD; platelet-derived growth factor D	K05450 PDGFC_D; platelet derived growth factor C/D 
C    104843371 PDGFC; platelet-derived growth factor C	K05450 PDGFC_D; platelet derived growth factor C/D 
C    104840366 VEGFA; vascular endothelial growth factor A	K05448 VEGFA; vascular endothelial growth factor A 
C    104833366 VEGFC; LOW QUALITY PROTEIN: vascular endothelial growth factor C	K05449 VEGFC_D; vascular endothelial growth factor C/D 
C    104840549 FIGF; vascular endothelial growth factor D	K05449 VEGFC_D; vascular endothelial growth factor C/D 
C    104841952 PGF; placenta growth factor	K16859 PGF; placenta growth factor 
C    104838614 NGF; beta-nerve growth factor	K02582 NGFB; nerve growth factor, beta 
C    104836639 NTF3; neurotrophin-3	K04356 NTF3; neurotrophin 3 
C    104829468 BDNF; brain-derived neurotrophic factor	K04355 BDNF; brain-derived neurotrophic factor 
C    104843083 GDNF; glial cell line-derived neurotrophic factor isoform X1	K05452 GDNF; glial cell derived neurotrophic factor 
C    104828544 NRTN; neurturin	K25414 NRTN; neurturin 
C    104841080 ARTN; artemin	K25415 ARTN; artemin 
C    104828827 FGF17; fibroblast growth factor 17	K04358 FGF; fibroblast growth factor 
C    104829156 FGF22; fibroblast growth factor 22	K04358 FGF; fibroblast growth factor 
C    104829443 FGF3; fibroblast growth factor 3	K04358 FGF; fibroblast growth factor 
C    104829444 FGF4; fibroblast growth factor 4	K04358 FGF; fibroblast growth factor 
C    104830119 FGF8; fibroblast growth factor 8 isoform X1	K04358 FGF; fibroblast growth factor 
C    104832712 FGF16; fibroblast growth factor 16	K04358 FGF; fibroblast growth factor 
C    104833429 FGF20; fibroblast growth factor 20	K04358 FGF; fibroblast growth factor 
C    104834504 FGF7; fibroblast growth factor 7	K04358 FGF; fibroblast growth factor 
C    104834951 FGF9; fibroblast growth factor 9	K04358 FGF; fibroblast growth factor 
C    104836646 FGF6; fibroblast growth factor 6	K04358 FGF; fibroblast growth factor 
C    104836747 FGF5; fibroblast growth factor 5	K04358 FGF; fibroblast growth factor 
C    104839043 FGF18; fibroblast growth factor 18	K04358 FGF; fibroblast growth factor 
C    104843061 FGF10; fibroblast growth factor 10	K04358 FGF; fibroblast growth factor 
C    104834824 FGF13; fibroblast growth factor 13 isoform X1	K22413 FGF11_12_13; fibroblast growth factor 11/12/13 
C    104835191 FGF12; fibroblast growth factor 12 isoform X1	K22413 FGF11_12_13; fibroblast growth factor 11/12/13 
C    104838528 FGF14; fibroblast growth factor 14	K23920 FGF14; fibroblast growth factor 14 
C    104829445 FGF19; fibroblast growth factor 19	K22603 FGF19; fibroblast growth factor 19 
C    104836721 FGF23; fibroblast growth factor 23	K22428 FGF23; fibroblast growth factor 23 
C    104831471 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1	K05455 NRG1; neuregulin 1 
C    104830828 NRG2; pro-neuregulin-2, membrane-bound isoform	K05456 NRG2; neuregulin 2 
C    104831999 NRG3; pro-neuregulin-3, membrane-bound isoform	K05457 NRG3; neuregulin 3 
C    104834694 NRG4; pro-neuregulin-4, membrane-bound isoform	K05458 NRG4; neuregulin 4 
C    104831000 IGF1; insulin-like growth factor I	K05459 IGF1; insulin-like growth factor 1 
C    104829566 IGF2; insulin-like growth factor II	K13769 IGF2; insulin-like growth factor 2 
C    104840279 HGF; hepatocyte growth factor	K05460 HGF; hepatocyte growth factor 
C    104843353 EGF; pro-epidermal growth factor	K04357 EGF; epidermal growth factor 
C    104836754 EREG; proepiregulin	K09784 EREG; epiregulin 
C    104836828 AREG; amphiregulin	K09782 AREG; amphiregulin 
C    104828343 KITLG; kit ligand	K05461 KITLG; KIT ligand 
C    104829394 EFNA5; ephrin-A5	K05462 EFNA; ephrin-A 
C    104829714 EFNA1; ephrin-A1	K05462 EFNA; ephrin-A 
C    104829716 EFNA3; ephrin-A3	K05462 EFNA; ephrin-A 
C    104829717 EFNA4; ephrin-A4	K05462 EFNA; ephrin-A 
C    104834784 EFNB1; ephrin-B1 isoform X1	K05463 EFNB; ephrin-B 
C    104838560 EFNB2; ephrin-B2	K05463 EFNB; ephrin-B 
C    104836962 GAS6; growth arrest-specific protein 6	K05464 GAS6; growth arrest-specific 6 
C    104837704 ANGPT1; angiopoietin-1	K05465 ANGPT1; angiopoietin 1 
C    104827816 ANGPT2; angiopoietin-2 isoform X1	K05466 ANGPT2; angiopoietin 2 
C    104832983 ANGPT4; angiopoietin-4	K05467 ANGPT4; angiopoietin 4 
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A<b>Neuropeptides</b>
B  GPCR binding
C    104828763 AGT; angiotensinogen	K09821 AGT; angiotensinogen 
C    104835129 KNG1; kininogen-1	K03898 KNG; kininogen 
C    104828267 NTS; neurotensin/neuromedin N	K05235 NTS; neurotensin 
C    104834336 NMB; neuromedin-B	K05223 NMB; neuromedin B 
C    104841423 GRP; gastrin-releasing peptide	K05224 GRP; gastrin-releasing peptide 
C    104828409 CCK; cholecystokinin	K05226 CCK; cholecystokinin 
C    104835361 EDN1; endothelin-1	K16366 EDN1; endothelin-1 
C    104837233 EDN2; endothelin-2	K16367 EDN2; endothelin-2 
C    104828677 GAL; galanin peptides isoform X1	K05244 GAL; galanin 
C    104842464 MLN; LOW QUALITY PROTEIN: promotilin	K05265 MLN; motilin 
C    104836177 NMU; neuromedin-U	K05249 NMU; neuromedin U 
C    104838059 NPVF; pro-FMRFamide-related neuropeptide VF	K25692 NPVF; pro-FMRFamide-related neuropeptide VF 
C    104840761 NPS; neuropeptide S	K25691 NPS; neuropeptide S 
C    104838064 NPY; pro-neuropeptide Y	K05232 NPY; neuropeptide Y 
C    104832138 NPB; neuropeptide B	K05267 NPB; preproneuropeptide B 
C    104841479 POMC; pro-opiomelanocortin	K05228 POMC; proopiomelanocortin 
C    104841336 PENK; proenkephalin-A	K18832 PENK; proenkephalin A 
C    104832993 PDYN; proenkephalin-B	K15840 PDYN; proenkephalin B (prodynorphin) 
C    104841469 PNOC; prepronociceptin	K25696 PNOC; prepronociceptin 
C    104834031 QRFP; orexigenic neuropeptide QRFP	K25693 QRFP; orexigenic neuropeptide QRFP 
C    104840076 neurophysin 1	K05243 OXT; oxytocin-neurophysin 1 
C    104835233 SST; somatostatin	K05237 SST; somatostatin 
C    104837900 CORT; cortistatin	K05238 CORT; cortistatin 
C    104828048 TAC1; protachykinin-1	K05239 TAC1; tachykinin 1 
C    104830446 UTS2; urotensin-2	K05248 UTS2; urotensin 2 
C    104835189 UTS2B; urotensin-2B	K24267 UTS2B; urotensin-2B 
C    104840077 vasotocin-neurophysin VT	K05242 AVP; arginine vasopressin 
C    104828407 PRLH; prolactin-releasing peptide	K05269 PRH; prolactin-releasing peptide 
C    104842941 HCRT; orexin	K05246 HCRT; hypocretin (orexin) neuropeptide 
C    104841875 CHGA; chromogranin-A	K19990 CHGA; chromogranin-A 
C    104836252 CHGB; secretogranin-1 isoform X1	K19991 CHGB; chromogranin-B 
C    104832222 SCG2; secretogranin-2	K25732 SCG2; secretogranin-2 
C    104834486 SCG3; secretogranin-3 isoform X1	K25733 SCG3; secretogranin-3 
C    104835942 SCG5; neuroendocrine protein 7B2	K25734 SCG5; neuroendocrine protein 7B2 
C    104828852 GNRH1; progonadoliberin-1	K05252 GNRH; gonadotropin-releasing hormone 
C    104833426 TRH; thyrotropin releasing hormone	K05253 TRH; thyrotropin-releasing hormone 
C    104843240 uncharacterized protein LOC104843240	K22000 RLN3; relaxin 3 
C    104828075 INSL5; insulin-like peptide INSL5	K22001 INSL5; insulin-like 5 
C    104830999 PMCH; pro-MCH	K05229 PMCH; pro-melanin-concentrating hormone 
C    104843031 gastrin/cholecystokinin-like peptide	K13768 GAST; gastrin 
C    104829526 CALCB; calcitonin gene-related peptide 2 isoform X1	K12332 CALC; calcitonin 
C    104829587 ADM; ADM	K12333 ADM; adrenomedullin 
C    104830867 ADM2; ADM2	K25343 ADM2; adrenomedullin-2 
C    104830897 IAPP; islet amyloid polypeptide	K08039 IAPP; islet amyloid polypeptide 
C    104837050 CRH; corticoliberin	K05256 CRH; corticotropin-releasing hormone 
C    104840231 UCN3; urocortin-3	K05257 UCN2_3; urocortin 2/3 
C    104842986 GIP; gastric inhibitory polypeptide	K05258 GIP; gastric inhibitory polypeptide 
C    104831799 GCG; glucagon	K05259 GCG; glucagon 
C    104832385 exendin-3-like	K05259 GCG; glucagon 
C    104829491 PTH; parathyroid hormone	K05261 PTH; parathyroid hormone 
C    104836002 ADCYAP1; pituitary adenylate cyclase-activating polypeptide	K05262 ADCYAP; pituitary adenylate cyclase-activating polypeptide 
C    104840720 VIP; VIP peptides isoform X1	K05264 VIP; vasoactive intestinal peptide 
C    104836632 PTHLH; parathyroid hormone-related protein	K22608 PTHLH; parathyroid hormone-related hormone 
C    104830645 CGA; glycoprotein hormones alpha chain	K08522 CGA; glycoprotein hormones alpha chain 
C    104829473 FSHB; follitropin subunit beta	K05250 FSHB; follitropin subunit beta 
C    104838631 TSHB; thyrotropin subunit beta	K05251 TSHB; thyrotropin subunit beta 
C    104842064 GPHB5; glycoprotein hormone beta-5	K25484 GPHB5; glycoprotein hormone beta-5 
B  Unclassified
C    104837885 natriuretic peptides A	K12334 NPPA; natriuretic peptide A 
C    104831750 C-type natriuretic peptide 2-like	K12336 NPPC; natriuretic peptide C 
C    104837883 NPPC; C-type natriuretic peptide	K12336 NPPC; natriuretic peptide C 
C    104828041 NXPH1; neurexophilin-1	K16656 NXPH1; neurexophilin-1 
C    104836562 NXPH2; neurexophilin-2	K16657 NXPH2; neurexophilin-2 
C    104842852 NXPH3; neurexophilin-3	K16658 NXPH3; neurexophilin-3 
C    104830361 NXPH4; neurexophilin-4	K25711 NXPH4; neurexophilin-4 
C    104829565 INS; insulin	K04526 INS; insulin 
C    104835264 PRL; prolactin isoform X1	K05439 PRL; prolactin 
C    104835877 prolactin-like	K05439 PRL; prolactin 
C    104829178 cocaine- and amphetamine-regulated transcript protein-like	K25453 CARTPT; cocaine- and amphetamine-regulated transcript protein 
C    104838422 CARTPT; cocaine- and amphetamine-regulated transcript protein	K25453 CARTPT; cocaine- and amphetamine-regulated transcript protein 
C    104841917 AGRP; agouti-related protein	K05231 AGRP; agouti related protein 
C    104836502 DBI; acyl-CoA-binding protein	K08762 DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) 
C    104833206 CBLN4; cerebellin-4	K24235 CBLN; cerebellin 
C    104838271 CBLN2; cerebellin-2	K24235 CBLN; cerebellin 
C    104842714 CBLN1; LOW QUALITY PROTEIN: cerebellin-1	K24235 CBLN; cerebellin 
C    104832198 ADIPOQ; adiponectin	K07296 ADIPOQ; adiponectin 
C    104840268 NAMPT; nicotinamide phosphoribosyltransferase	K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12] 
C    104829532 NUCB2; nucleobindin-2	K20371 NUCB; nucleobindin 
C    104832587 UBL5; ubiquitin-like protein 5	K13113 UBL5; ubiquitin-like protein 5 
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#Last updated: April 23, 2025