+E Replication protein KO
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DNA Replication Proteins - Hyphomicrobium sp. MC1
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D HYPMC_4171 rnhA; Ribonuclease HI (RNase HI) K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
D HYPMC_4640 AAA ATPase K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D HYPMC_0038 Histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D HYPMC_2915 hupB; DNA-binding protein HU-beta (NS1) (HU-1) K03530 hupB; DNA-binding protein HU-beta
D HYPMC_2656 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D HYPMC_0542 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D HYPMC_0001 dnaA; DNA replication initiator protein, transcriptional regulator of replication and housekeeping genes K02313 dnaA; chromosomal replication initiator protein
D HYPMC_2040 dnaB; replicative DNA helicase (dnaB) K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D HYPMC_2140 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D HYPMC_1346 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D HYPMC_2022 putative Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E HYPMC_2877 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E HYPMC_0002 dnaN; DNA polymerase III, beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E HYPMC_3178 DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E HYPMC_4541 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E HYPMC_2030 AAA ATPase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E HYPMC_4563 dnaQ; DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E HYPMC_0633 dnaX; DNA polymerase III, tau and gamma subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E HYPMC_4171 rnhA; Ribonuclease HI (RNase HI) K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E HYPMC_0862 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
E HYPMC_4153 rnhB; Ribonuclease HII (RNase HII) K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E HYPMC_3913 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E HYPMC_0346 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E HYPMC_4171 rnhA; Ribonuclease HI (RNase HI) K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E HYPMC_0862 rnhB; Ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
E HYPMC_4153 rnhB; Ribonuclease HII (RNase HII) K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
C HYPMC_1352 gyrA; DNA gyrase, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C HYPMC_0006 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C HYPMC_2510 parC; DNA topoisomerase IV subunitA K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C HYPMC_1105 parE; DNA topoisomerase IV, subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C HYPMC_1126 TopA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022