+F Repair protein KO
#
DNA Repair and Recombination Proteins - Helobdella robusta
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D HELRODRAFT_185055 hypothetical protein K10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]
D HELRODRAFT_62279 hypothetical protein K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
C BER (base exicision repair)
D DNA glycosylases
E HELRODRAFT_157191 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HELRODRAFT_71611 hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E HELRODRAFT_124128 hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E HELRODRAFT_143241 hypothetical protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E HELRODRAFT_194902 hypothetical protein K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
E HELRODRAFT_194432 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E HELRODRAFT_158200 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E HELRODRAFT_186002 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E HELRODRAFT_94522 hypothetical protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F HELRODRAFT_91243 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F HELRODRAFT_71825 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
F HELRODRAFT_190144 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F HELRODRAFT_190906 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F HELRODRAFT_191255 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F HELRODRAFT_75183 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F HELRODRAFT_127849 hypothetical protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E HELRODRAFT_185039 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E HELRODRAFT_66570 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E HELRODRAFT_184959 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E HELRODRAFT_188891 hypothetical protein K10803 XRCC1; DNA-repair protein XRCC1
E HELRODRAFT_113751 hypothetical protein K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E HELRODRAFT_62577 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E HELRODRAFT_109229 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E HELRODRAFT_157878 hypothetical protein K10802 HMGB1; high mobility group protein B1
E HELRODRAFT_161346 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E HELRODRAFT_95414 hypothetical protein K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
E HELRODRAFT_194677 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E HELRODRAFT_190218 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E HELRODRAFT_190616 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F HELRODRAFT_194593 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F HELRODRAFT_185916 hypothetical protein K10839 RAD23; UV excision repair protein RAD23
F HELRODRAFT_73405 hypothetical protein K10840 CETN2; centrin-2
E Cul4-DDB2 complex
F HELRODRAFT_86393 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F HELRODRAFT_185316 hypothetical protein K10609 CUL4; cullin 4
F HELRODRAFT_187538 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F HELRODRAFT_103917 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F HELRODRAFT_158265 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F HELRODRAFT_86723 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F HELRODRAFT_193523 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F HELRODRAFT_102505 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F HELRODRAFT_72376 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F HELRODRAFT_158187 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F HELRODRAFT_97005 hypothetical protein K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F HELRODRAFT_85938 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F HELRODRAFT_86044 hypothetical protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F HELRODRAFT_91608 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F HELRODRAFT_173679 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F HELRODRAFT_185710 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F HELRODRAFT_65246 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F HELRODRAFT_86309 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F HELRODRAFT_104718 hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F HELRODRAFT_165578 hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F HELRODRAFT_157577 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F HELRODRAFT_63271 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F HELRODRAFT_74285 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F HELRODRAFT_92790 hypothetical protein K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F HELRODRAFT_163066 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F HELRODRAFT_154955 hypothetical protein K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F HELRODRAFT_86393 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F HELRODRAFT_185316 hypothetical protein K10609 CUL4; cullin 4
F HELRODRAFT_187538 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F HELRODRAFT_88668 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F HELRODRAFT_108854 hypothetical protein K10841 ERCC6; DNA excision repair protein ERCC-6
F HELRODRAFT_140459 hypothetical protein K23720 UVSSA; UV-stimulated scaffold protein A
F HELRODRAFT_84564 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E HELRODRAFT_155693 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E HELRODRAFT_105484 hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E HELRODRAFT_102185 hypothetical protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E HELRODRAFT_185095 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E HELRODRAFT_185480 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E HELRODRAFT_69505 hypothetical protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E HELRODRAFT_80663 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E HELRODRAFT_94730 hypothetical protein K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E HELRODRAFT_90768 hypothetical protein K06634 CCNH; cyclin H
E HELRODRAFT_186265 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E HELRODRAFT_114692 hypothetical protein K07466 RFA1; replication factor A1
E HELRODRAFT_170399 hypothetical protein K10739 RFA2; replication factor A2
E HELRODRAFT_181826 hypothetical protein K10740 RPA3; replication factor A3
D Other NER factors
E HELRODRAFT_156075 hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E HELRODRAFT_63358 hypothetical protein K10849 ERCC1; DNA excision repair protein ERCC-1
E HELRODRAFT_98781 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E HELRODRAFT_188230 hypothetical protein K10846 ERCC5; DNA excision repair protein ERCC-5
E HELRODRAFT_84693 hypothetical protein K03869 CUL3; cullin 3
E HELRODRAFT_101759 hypothetical protein K03869 CUL3; cullin 3
E HELRODRAFT_97655 hypothetical protein K10612 CUL5; cullin 5
E HELRODRAFT_83279 hypothetical protein K03872 ELOC; elongin-C
E HELRODRAFT_166296 hypothetical protein K03873 ELOB; elongin-B
E HELRODRAFT_181795 hypothetical protein K03873 ELOB; elongin-B
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E HELRODRAFT_190918 hypothetical protein K08735 MSH2; DNA mismatch repair protein MSH2
E HELRODRAFT_187909 hypothetical protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E HELRODRAFT_190644 hypothetical protein K08734 MLH1; DNA mismatch repair protein MLH1
E HELRODRAFT_157945 hypothetical protein K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E HELRODRAFT_91243 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E HELRODRAFT_71825 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
E HELRODRAFT_190144 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E HELRODRAFT_114692 hypothetical protein K07466 RFA1; replication factor A1
E HELRODRAFT_170399 hypothetical protein K10739 RFA2; replication factor A2
E HELRODRAFT_181826 hypothetical protein K10740 RPA3; replication factor A3
D RFC (replication factor C)
E HELRODRAFT_112087 hypothetical protein K10754 RFC1; replication factor C subunit 1
E HELRODRAFT_185082 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E HELRODRAFT_186210 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E HELRODRAFT_87902 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E HELRODRAFT_185039 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
E HELRODRAFT_106350 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E HELRODRAFT_157878 hypothetical protein K10802 HMGB1; high mobility group protein B1
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E HELRODRAFT_192564 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D BRCA1-core complex
E HELRODRAFT_181375 hypothetical protein K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E HELRODRAFT_188701 hypothetical protein K20776 BABAM; BRISC and BRCA1-A complex member 1
E HELRODRAFT_193162 hypothetical protein K12173 BRE; BRCA1-A complex subunit BRE
E HELRODRAFT_150937 hypothetical protein K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E HELRODRAFT_189813 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
E HELRODRAFT_190326 hypothetical protein K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E HELRODRAFT_192564 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D BRCA complex
E HELRODRAFT_192253 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
D RecA family proteins
E HELRODRAFT_66822 hypothetical protein K10869 RAD51L1; RAD51-like protein 1
D Rad52 family proteins
E HELRODRAFT_64872 hypothetical protein K10873 RAD52; DNA repair and recombination protein RAD52
E HELRODRAFT_191375 hypothetical protein K10874 RDM1; RAD52 motif-containing protein 1
D Rad54 family proteins
E HELRODRAFT_157121 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E HELRODRAFT_165757 hypothetical protein K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
E HELRODRAFT_94672 hypothetical protein K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E HELRODRAFT_162528 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E HELRODRAFT_189333 hypothetical protein K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E HELRODRAFT_94851 hypothetical protein K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E HELRODRAFT_99171 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E HELRODRAFT_114559 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E HELRODRAFT_162040 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E HELRODRAFT_114692 hypothetical protein K07466 RFA1; replication factor A1
E HELRODRAFT_170399 hypothetical protein K10739 RFA2; replication factor A2
E HELRODRAFT_181826 hypothetical protein K10740 RPA3; replication factor A3
D Protein phosphatase 4
E HELRODRAFT_186046 hypothetical protein K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E HELRODRAFT_101507 hypothetical protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E HELRODRAFT_111611 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E HELRODRAFT_162723 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E HELRODRAFT_194550 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
D Other HR factors
E HELRODRAFT_193600 hypothetical protein K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E HELRODRAFT_190612 hypothetical protein K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E HELRODRAFT_189672 hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E HELRODRAFT_184679 hypothetical protein K10992 SFR1; Swi5-dependent recombination DNA repair protein 1
E HELRODRAFT_77631 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E HELRODRAFT_167939 hypothetical protein K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E HELRODRAFT_99671 hypothetical protein K11339 MORF4L1; mortality factor 4-like protein 1
E HELRODRAFT_111791 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E HELRODRAFT_85388 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E HELRODRAFT_99321 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E HELRODRAFT_94331 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E HELRODRAFT_193042 hypothetical protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E HELRODRAFT_192857 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E HELRODRAFT_159097 hypothetical protein K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E HELRODRAFT_192564 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E HELRODRAFT_75449 hypothetical protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E HELRODRAFT_194751 hypothetical protein K10886 XRCC4; DNA-repair protein XRCC4
D X-family DNA polymerases
E HELRODRAFT_161346 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E HELRODRAFT_184959 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E HELRODRAFT_62577 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E HELRODRAFT_92422 hypothetical protein K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
E HELRODRAFT_116381 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E HELRODRAFT_82533 hypothetical protein K25792 JMJD8; jumonji domain-containing protein 8
C FA (Fanconi anemia) pathway
D FA core complex
E HELRODRAFT_173292 hypothetical protein K10898 FAAP24; fanconi anemia-associated protein
D FA core complex binding factors
E HELRODRAFT_77283 hypothetical protein K11511 APITD1; centromere protein S
E HELRODRAFT_62061 hypothetical protein K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E HELRODRAFT_99171 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E HELRODRAFT_114559 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E HELRODRAFT_162040 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
D Downstream FA components
E HELRODRAFT_192253 hypothetical protein K08775 BRCA2; breast cancer 2 susceptibility protein
E HELRODRAFT_189813 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E HELRODRAFT_193827 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E HELRODRAFT_160268 hypothetical protein K11137 TELO2; telomere length regulation protein
E HELRODRAFT_184854 hypothetical protein K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
E HELRODRAFT_162754 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E HELRODRAFT_66479 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D HELRODRAFT_116221 hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D HELRODRAFT_193420 hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D HELRODRAFT_192588 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D HELRODRAFT_185973 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D HELRODRAFT_186617 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D HELRODRAFT_75560 hypothetical protein K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D HELRODRAFT_185499 hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D HELRODRAFT_185270 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D HELRODRAFT_185039 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D HELRODRAFT_73845 hypothetical protein K24051 SPRTN; SprT-like domain-contaning protein Spartan
D HELRODRAFT_68915 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D HELRODRAFT_62760 hypothetical protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D HELRODRAFT_186499 hypothetical protein K10903 HUS1; HUS1 checkpoint protein
D HELRODRAFT_156866 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D HELRODRAFT_130916 hypothetical protein K06662 HRAD17; cell cycle checkpoint protein
D HELRODRAFT_185082 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D HELRODRAFT_186210 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D HELRODRAFT_87902 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D HELRODRAFT_156866 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D HELRODRAFT_89874 hypothetical protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D HELRODRAFT_189853 hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D HELRODRAFT_160268 hypothetical protein K11137 TELO2; telomere length regulation protein
D HELRODRAFT_174193 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
D HELRODRAFT_158818 hypothetical protein K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D HELRODRAFT_187805 hypothetical protein K23390 BAG6; large proline-rich protein BAG6
D HELRODRAFT_185563 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
D HELRODRAFT_75748 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D HELRODRAFT_73987 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D HELRODRAFT_107137 hypothetical protein K04451 TP53; tumor protein p53
D HELRODRAFT_189278 hypothetical protein K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D HELRODRAFT_83726 hypothetical protein K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D HELRODRAFT_101296 hypothetical protein K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D HELRODRAFT_114528 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D HELRODRAFT_186472 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D HELRODRAFT_185239 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D HELRODRAFT_75495 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D HELRODRAFT_185424 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D HELRODRAFT_64550 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D HELRODRAFT_153934 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D HELRODRAFT_155141 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D HELRODRAFT_116410 hypothetical protein K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D HELRODRAFT_106737 hypothetical protein K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D HELRODRAFT_82785 hypothetical protein K17336 PLS3; plastin-3
D HELRODRAFT_111405 hypothetical protein K17336 PLS3; plastin-3
D HELRODRAFT_105374 hypothetical protein K17336 PLS3; plastin-3
D HELRODRAFT_76519 hypothetical protein K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D HELRODRAFT_150398 hypothetical protein K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D HELRODRAFT_193305 hypothetical protein K22422 DONSON; protein downstream neighbor of Son
D HELRODRAFT_142718 hypothetical protein K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D HELRODRAFT_193180 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D HELRODRAFT_117195 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D HELRODRAFT_191126 hypothetical protein K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
C Nucleases
D HELRODRAFT_188648 hypothetical protein K15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]
D HELRODRAFT_85315 hypothetical protein K21813 ENDOV; endonuclease V [EC:3.1.26.-]
D HELRODRAFT_189194 hypothetical protein K25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]
D HELRODRAFT_70669 hypothetical protein K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D HELRODRAFT_74949 hypothetical protein K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D HELRODRAFT_186274 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D HELRODRAFT_155960 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D HELRODRAFT_186289 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D HELRODRAFT_185026 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D HELRODRAFT_159814 hypothetical protein K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D HELRODRAFT_68359 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D HELRODRAFT_106206 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D HELRODRAFT_185290 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D HELRODRAFT_93558 hypothetical protein K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D HELRODRAFT_154313 hypothetical protein K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
C BER (base exicision repair)
D DNA glycosylases
E HELRODRAFT_157191 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E HELRODRAFT_143241 hypothetical protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E HELRODRAFT_158200 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E HELRODRAFT_84352 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D HELRODRAFT_84352 hypothetical protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D HELRODRAFT_68359 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024