+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Hirundo rustica (Barn swallow)
%
!
AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 120748756 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 120750768 RNGTT; mRNA-capping enzyme K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 120765782 CDK7; cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 120750139 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 120758011 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 120758991 RAMAC; RNA guanine-N7 methyltransferase activating subunit isoform X1 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 120765302 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 120757209 NCBP2; nuclear cap-binding protein subunit 2 isoform X1 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 120762037 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 120757572 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 120751407 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 120753729 CPSF7; cleavage and polyadenylation specificity factor subunit 7 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 120754101 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 120764891 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 120754022 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 120750584 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 120759478 CPSF4; cleavage and polyadenylation specificity factor subunit 4 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 120761097 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 120753387 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 120761967 pre-mRNA 3'-end-processing factor FIP1-like isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 120758404 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 120748088 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 120760480 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 120749759 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 120762359 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 120760202 CSTF1; cleavage stimulation factor subunit 1 isoform X1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 120764837 LOW QUALITY PROTEIN: cleavage stimulation factor subunit 2-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 120765641 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 120754725 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
D U7-dependent histone pre-mRNA processing factors
E 120759985 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 120760697 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 120762805 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 120751935 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 120764135 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 120763161 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 120759322 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 120754022 CPSF2; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 120750584 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 120764837 LOW QUALITY PROTEIN: cleavage stimulation factor subunit 2-like K14407 CSTF2; cleavage stimulation factor subunit 2
E 120765641 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 120752979 histone RNA hairpin-binding protein-like K18710 SLBP; histone RNA hairpin-binding protein
E 120753358 histone RNA hairpin-binding protein-like K18710 SLBP; histone RNA hairpin-binding protein
E 120750434 CASP8AP2; CASP8-associated protein 2 isoform X1 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 120761316 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 120747834 SUPT5H; transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 120753017 METTL14; N6-adenosine-methyltransferase non-catalytic subunit isoform X1 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 120755232 METTL4; N(6)-adenine-specific methyltransferase METTL4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 120748596 METTL16; RNA N6-adenosine-methyltransferase METTL16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 120750005 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 120749767 VIRMA; protein virilizer homolog K22910 VIRMA; protein virilizer
E 120758442 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 120762708 RBM15; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 120748401 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 120752015 CBLL1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase Hakai K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 120753849 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 120765399 TENT2; poly(A) RNA polymerase GLD2 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E 120754901 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 120748494 RBM26; RNA-binding protein 26 isoform X1 K13192 RBM26; RNA-binding protein 26
E 120757852 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 120759624 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 120762241 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 120761338 DHX40; probable ATP-dependent RNA helicase DHX40 isoform X1 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 120751756 DNA/RNA-binding protein KIN17-like K13102 KIN; DNA/RNA-binding protein KIN17
D 120752411 KIN; DNA/RNA-binding protein KIN17 isoform X1 K13102 KIN; DNA/RNA-binding protein KIN17
D 120755268 METTL8; tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 120759839 METTL22; methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 120763234 TENT5B; terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 120750781 TENT5A; terminal nucleotidyltransferase 5A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 120749181 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 120765378 terminal nucleotidyltransferase 5C K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 120764856 terminal nucleotidyltransferase 5C-like K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 120754100 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 120747754 SRRT; serrate RNA effector molecule homolog K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 120764253 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 120756428 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 120760842 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 120750592 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 120758148 CCDC174; coiled-coil domain-containing protein 174 isoform X1 K25178 CCDC174; coiled-coil domain-containing protein 174
E 120763795 CASC3; protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 120749329 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 120753586 PNN; pinin K13114 PNN; pinin
E 120759596 RNPS1; RNA-binding protein with serine-rich domain 1 isoform X1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 120763044 SRRM1; serine/arginine repetitive matrix protein 1 isoform X2 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 120761729 THOC1; THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 120762139 THOC2; THO complex subunit 2 isoform X1 K12879 THOC2; THO complex subunit 2
E 120759212 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 120760842 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 120760609 THOC5; THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 120758059 THOC7; THO complex subunit 7 homolog K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 120749298 PCID2; PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 120751891 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 120762030 CETN2; centrin-2 K10840 CETN2; centrin-2
E 120765887 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 120755128 MCM3AP; germinal-center associated nuclear protein isoform X1 K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 120756812 TPR; nucleoprotein TPR isoform X1 K09291 TPR; nucleoprotein TPR
E 120760213 RAE1; mRNA export factor RAE1 K14298 RAE1; mRNA export factor
E 120758063 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 120752354 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 120761049 NUP85; nuclear pore complex protein Nup85 isoform X1 K14304 NUP85; nuclear pore complex protein Nup85
E 120749865 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 120752003 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 120752578 NUP54; nucleoporin p54 isoform X1 K14308 NUP54; nuclear pore complex protein Nup54
E 131378688 nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 120761995 nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 120761355 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 120757669 NUP93; nuclear pore complex protein Nup93 isoform X1 K14309 NUP93; nuclear pore complex protein Nup93
E 120748485 NUP98; nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 120752278 NUP107; nuclear pore complex protein Nup107 isoform X1 K14301 NUP107; nuclear pore complex protein Nup107
E 120750765 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 120761898 NUP188; nucleoporin NUP188 K14311 NUP188; nuclear pore complex protein Nup188
E 120764147 NUP153; nuclear pore complex protein Nup153 isoform X1 K14296 NUP153; nuclear pore complex protein Nup153
E 120765266 NUP155; nuclear pore complex protein Nup155 K14312 NUP155; nuclear pore complex protein Nup155
E 120753686 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 120755438 NUP35; nucleoporin NUP35 K14313 NUP35; nuclear pore complex protein Nup53
E 120751701 NUP205; nuclear pore complex protein Nup205 isoform X1 K14310 NUP205; nuclear pore complex protein Nup205
E 120758334 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 120761728 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 120761528 putative nuclear envelope pore membrane protein POM 121B K14316 POM121; nuclear pore complex protein Nup121
E 120748547 NUP58; nucleoporin p58/p45 isoform X1 K14307 NUPL1; nucleoporin p58/p45
E 120760539 nucleoporin NUP42-like isoform X1 K14321 NUPL2; nucleoporin-like protein 2
E 120760537 nucleoporin NUP42-like K14321 NUPL2; nucleoporin-like protein 2
E 120756602 NDC1; nucleoporin NDC1 isoform X1 K14315 NDC1; nucleoporin NDC1
E 120749630 RGPD4; ranBP2-like and GRIP domain-containing protein 4 isoform X1 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 120757447 SENP2; sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 120764457 AAAS; aladin K14320 AAAS; aladin
E 120765887 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 120761829 GLE1; mRNA export factor GLE1 K18723 GLE1; nucleoporin GLE1
E 120762112 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 120760648 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 120747973 acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 120763539 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 120763330 ELAVL1; ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 120764732 ELAVL3; ELAV-like protein 3 isoform X2 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 120765693 ELAVL2; ELAV-like protein 2 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 120756419 ELAVL4; ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 120759051 FAF2; FAS-associated factor 2 isoform X1 K18726 FAF2; FAS-associated factor 2
E 120765086 VCP; transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 120753681 VCPKMT; protein N-lysine methyltransferase METTL21D K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 120764745 transportin-2-like K18727 TNPO2; transportin-2
E 120748317 TNPO2; LOW QUALITY PROTEIN: transportin-2 K18727 TNPO2; transportin-2
E 120751001 XPO1; exportin-1 isoform X1 K14290 XPO1; exportin-1
E 120763974 XPO7; exportin-7 K18460 XPO7; exportin-7
E 120751570 RANGAP1; ran GTPase-activating protein 1 isoform X1 K14319 RANGAP1; Ran GTPase-activating protein 1
E 120761260 TAF15; TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 120752651 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 120759216 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 120756984 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 120756926 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 120754246 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 120762405 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X6 K03260 EIF4G; translation initiation factor 4G
E 120756943 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 120764701 EIF4B; eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 120761196 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 120764044 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 isoform X1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 120756041 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 120760382 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 120754336 ANGEL1; protein angel homolog 1 isoform X1 K18729 ANGEL; protein angel
E 120750094 ANGEL2; protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 120762010 FMR1; fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 120756942 FXR1; RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 120759146 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 120749382 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 120759115 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 120753246 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 120758875 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120759029 CPEB4; cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120755619 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120748729 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 120756954 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 120763031 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 120764889 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 120760025 PABPC1L; polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 120764937 polyadenylate-binding protein-interacting protein 1-like isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 120765623 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 120759297 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 120753720 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 120764855 malignant T-cell-amplified sequence 1-like K07575 MCTS; malignant T-cell-amplified sequence
E 120765103 MCTS1; malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 120760749 DENR; density-regulated protein isoform X1 K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 120748602 DNA dC->dU-editing enzyme APOBEC-3F-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 120755870 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 120764494 PYM1; partner of Y14 and mago K14294 WIBG; partner of Y14 and mago
E 120755428 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 120763486 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 120760471 MSI1; RNA-binding protein Musashi homolog 1 isoform X3 K14411 MSI; RNA-binding protein Musashi
E 120761164 MSI2; RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 120750103 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 120765355 PELO; protein pelota homolog K06965 PELO; protein pelota
E 120757706 PABPN1L; embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 120762217 ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 120762599 DDX25; ATP-dependent RNA helicase DDX25 isoform X1 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 120764421 SARNP; SAP domain-containing ribonucleoprotein K18732 SARNP; SAP domain-containing ribonucleoprotein
E 120763210 RCC1; regulator of chromosome condensation isoform X1 K11493 RCC1; regulator of chromosome condensation
E 120763465 uncharacterized protein LOC120763465 K18733 LARP6; la-related protein 6
E 120758736 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 120759131 PURA; LOW QUALITY PROTEIN: transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 120764108 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 120751734 POLDIP3; polymerase delta-interacting protein 3 isoform X1 K22414 POLDIP3; polymerase delta-interacting protein 3
E 120762765 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 120758722 PATL2; LOW QUALITY PROTEIN: protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 120759259 ETF1; eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E 120759648 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 K03267 ERF3; peptide chain release factor subunit 3
E 120763421 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 120751807 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 120764883 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 120749045 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 120752973 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 120759117 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 120763994 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 120752588 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 120759323 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 120755692 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 120757441 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 120748744 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 120754477 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 120753646 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 120753660 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 120750203 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 120751298 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 120759904 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 120764237 SMG5; nonsense-mediated mRNA decay factor SMG5 K11125 SMG5; protein SMG5
E 120761192 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 120756362 SMG7; nonsense-mediated mRNA decay factor SMG7 isoform X1 K14409 SMG7; protein SMG7
E 120761500 SMG8; nonsense-mediated mRNA decay factor SMG8 K18734 SMG8; protein SMG8
E 120756954 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 120758606 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 120765698 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 120751415 GTPBP1; GTP-binding protein 1 isoform X1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 120765487 PUM3; pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 120758556 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
E 120758558 MYO5A; unconventional myosin-Va isoform X5 K10357 MYO5; myosin V
E 120765640 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 120758205 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 120752454 protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
D Factors that have mRNA localization signals
E 120758534 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 120759701 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 120760819 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 120749833 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 120758893 VIM; vimentin K07606 VIM; vimentin
E 120757734 metallothionein-2 K14739 MT1_2; metallothionein 1/2
E 120752847 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 120763423 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 120760501 T-box-containing protein TBX6L K10180 TBX6; T-box protein 6
E 120756026 NANOS1; nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 120761596 FUBP3; far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 120756285 FUBP1; far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 120760322 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 120750192 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 120748376 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 120759617 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 120764277 HAX1; LOW QUALITY PROTEIN: HCLS1-associated protein X-1 K16220 HAX1; HCLS1-associated protein X-1
E 120757116 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 120752953 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 120759997 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 120758256 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 120763325 PTBP1; polypyrimidine tract-binding protein 1 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 120758875 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120759029 CPEB4; cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120755619 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 120762010 FMR1; fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 120756942 FXR1; RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 120759146 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 120749382 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 120764381 PCBP2; poly(rC)-binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 120751994 poly(rC)-binding protein 3-like isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 120758219 PCBP4; poly(rC)-binding protein 4 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 120755063 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 120753672 CAPRIN1; caprin-1 isoform X1 K18743 CAPRIN1; caprin-1
E 120751776 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 120762345 YBX1; Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 120757041 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 120763178 protein argonaute-4 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 120763179 AGO3; protein argonaute-3 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 120763180 protein argonaute-1 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 120749830 AGO2; protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 120752651 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 120759216 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 120756984 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 120763421 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 120748729 DDX3X; ATP-dependent RNA helicase DDX3X K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 120762490 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 120763517 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 120764292 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 120758965 MEX3B; RNA-binding protein MEX3B isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 120764876 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 120760753 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 120757635 LSM14A; protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 120760317 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 120764381 PCBP2; poly(rC)-binding protein 2 K13162 PCBP2; poly(rC)-binding protein 2
E 120762345 YBX1; Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 120757115 LIMD1; LIM domain-containing protein 1 K16682 AJUBA; LIM domain-containing protein
E 120757639 WTIP; Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 120748602 DNA dC->dU-editing enzyme APOBEC-3F-like K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 120762798 MOV10; helicase MOV-10 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 120763268 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 120765690 proline-rich nuclear receptor coactivator 2-like K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 120764900 transportin-1-like K18752 TNPO1; transportin-1
E 120765164 TNPO1; transportin-1 K18752 TNPO1; transportin-1
E 120759904 SMG1; serine/threonine-protein kinase SMG1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 120764237 SMG5; nonsense-mediated mRNA decay factor SMG5 K11125 SMG5; protein SMG5
E 120761192 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 120756362 SMG7; nonsense-mediated mRNA decay factor SMG7 isoform X1 K14409 SMG7; protein SMG7
E 120754588 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 120750517 ZFP36L2; mRNA decay activator protein ZFP36L2 K18753 ZFP36L; butyrate response factor
E 120763154 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 120750358 LIN28B; protein lin-28 homolog B isoform X1 K18754 LIN28; protein lin-28
E 120752517 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 120751645 IPO8; importin-8 isoform X1 K18755 IPO8; importin-8
E 120755693 BICC1; protein bicaudal C homolog 1 isoform X1 K18756 BICC1; protein bicaudal C
E 120755428 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 120756314 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 120752730 LARP1B; la-related protein 1B isoform X4 K18757 LARP1; la-related protein 1
E 120759443 LARP1; la-related protein 1 K18757 LARP1; la-related protein 1
E 120760433 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 120765510 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 120758377 DCP1A; mRNA-decapping enzyme 1A isoform X1 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 120751817 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 120764089 LSM1; U6 snRNA-associated Sm-like protein LSm1 isoform X1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 120758087 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X1 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 120763393 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 120765898 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 120752615 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 120763557 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 120752349 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X1 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 120747920 kinesin light chain 1-like isoform X1 K10407 KLC; kinesin light chain
E 120754292 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 120758556 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
E 120758558 MYO5A; unconventional myosin-Va isoform X5 K10357 MYO5; myosin V
E 120765640 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 120751692 TUBAL3; tubulin alpha chain-like 3 K07374 TUBA; tubulin alpha
E 120752423 TUBA8; tubulin alpha-8 chain isoform X1 K07374 TUBA; tubulin alpha
E 120764463 tubulin alpha-1B chain K07374 TUBA; tubulin alpha
E 120764464 TUBA1A; tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 120764465 tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 120754853 tubulin alpha-4A chain-like K07374 TUBA; tubulin alpha
E 120754957 tubulin alpha-5 chain K07374 TUBA; tubulin alpha
E 120757006 tubulin alpha-3 chain-like isoform X1 K07374 TUBA; tubulin alpha
E 120762739 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 120758875 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120759029 CPEB4; cytoplasmic polyadenylation element-binding protein 4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120755619 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 120759115 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 120753246 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 120751732 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 120759821 TNRC6A; trinucleotide repeat-containing gene 6A protein K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 120761149 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 120758022 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X2 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 120751991 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 120751835 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 120753103 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 120759149 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 120753018 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 120759116 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 120757546 GARRE1; granule associated Rac and RHOG effector protein 1 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 120757327 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 120764446 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 120748409 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 120751842 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 120752051 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 120758501 protein BTG1-like K14443 TOB; protein Tob/BTG
E 120762570 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 120761045 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 120762940 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 120760382 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 120753705 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 120758586 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 120757807 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 120751807 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 120764883 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 120749045 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 120759218 TRIM71; E3 ubiquitin-protein ligase TRIM71 isoform X2 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 120748370 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 120749969 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 120753461 ZAR1; zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 120749370 ZAR1L; protein ZAR1-like K18762 ZAR1; zygote arrest protein 1
E 120763219 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
E 120760007 YTHDF1; YTH domain-containing family protein 1 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 120750454 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 120763950 TIA1; cytotoxic granule associated RNA binding protein TIA1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 120756234 TIAL1; nucleolysin TIAR isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 120763031 PABPC4; polyadenylate-binding protein 4 K13126 PABPC; polyadenylate-binding protein
E 120764889 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 120760025 PABPC1L; polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 120752953 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 120759997 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 120762010 FMR1; fragile X messenger ribonucleoprotein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 120756942 FXR1; RNA-binding protein FXR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 120763330 ELAVL1; ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 120759167 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 120753211 G3BP2; ras GTPase-activating protein-binding protein 2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 120757146 EIF2A; eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 120759749 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 120756926 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 120750592 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 120764701 EIF4B; eukaryotic translation initiation factor 4B isoform X1 K03258 EIF4B; translation initiation factor 4B
E 120754246 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 120762405 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X6 K03260 EIF4G; translation initiation factor 4G
E 120756943 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 120763151 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 120764807 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 120748403 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 120750597 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 120764726 small ribosomal subunit protein RACK1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 120761764 TRAF2; TNF receptor-associated factor 2 isoform X2 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 120748573 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 120764406 LARP4; la-related protein 4 isoform X2 K18763 LARP4; la-related protein 4
E 120749339 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 120758377 DCP1A; mRNA-decapping enzyme 1A isoform X1 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 120751817 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 120765510 DCP2; m7GpppN-mRNA hydrolase K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 120762490 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 120758586 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 120757807 EDC4; enhancer of mRNA-decapping protein 4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 120753705 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 120764089 LSM1; U6 snRNA-associated Sm-like protein LSm1 isoform X1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 120758087 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X1 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 120763393 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 120765898 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 120752615 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 120763557 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 120752349 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X1 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 120757041 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 120750202 XRN2; 5'-3' exoribonuclease 2 isoform X1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
D Other 5'-3' decay factors
E 120762575 DCPS; m7GpppX diphosphatase isoform X1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 120760792 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 120755970 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
E 120761692 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 120755962 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 120765499 EXOSC5; exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 120757620 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 120761473 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 120748535 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 120753212 EXOSC9; exosome complex component RRP45 isoform X1 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 120765423 DIS3; exosome complex exonuclease RRP44 isoform X1 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 120758746 DIS3L; DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 120762400 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 120750328 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 120757681 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
D TRAMP complex
E 120757837 TENT4B; terminal nucleotidyltransferase 4B K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 120757910 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 120765361 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 120765212 MTREX; exosome RNA helicase MTR4 isoform X1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 120765181 SKIC3; superkiller complex protein 3 K12600 SKI3; superkiller protein 3
E 120758548 SKIC8; superkiller complex protein 8 isoform X1 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 120753103 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 120759149 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 120758022 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X2 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 120751991 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X1 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 120751835 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 120753018 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 120759116 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 120755343 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 120755377 CNOT10; CCR4-NOT transcription complex subunit 10 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 120764446 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 120748409 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 120759779 PARN; poly(A)-specific ribonuclease PARN isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 120750349 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X2 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 120757160 DHX36; ATP-dependent DNA/RNA helicase DHX36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 120751842 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 120752051 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 120758501 protein BTG1-like K14443 TOB; protein Tob/BTG
E 120762570 BTG4; protein BTG4 K14443 TOB; protein Tob/BTG
E 120761045 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 120762940 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 120753022 NOCT; nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E 120752547 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 120759806 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 120762575 DCPS; m7GpppX diphosphatase isoform X1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 120758460 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 120758630 IREB2; iron-responsive element-binding protein 2 isoform X1 K22416 IREB2; iron-responsive element-binding protein 2
E 120760792 HELZ; probable helicase with zinc finger domain isoform X1 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 120760081 HELZ2; helicase with zinc finger domain 2 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 120754445 NRDE2; nuclear exosome regulator NRDE2 K26109 NRDE2; nuclear exosome regulator NRDE2
E 120753642 SAMD4A; protein Smaug homolog 1 K27396 SMG; protein Smaug
E 120747829 SAMD4B; LOW QUALITY PROTEIN: protein Smaug homolog 2 K27396 SMG; protein Smaug
E 120765022 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 120763239 ZC3H12A; endoribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 120764951 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 120749460 ZC3H12C; probable ribonuclease ZC3H12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 120750874 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 120753015 DROSHA; ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 120762668 REXO2; oligoribonuclease, mitochondrial K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 120749273 ENO2; gamma-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 120762387 ENO1; alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 120750525 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 120757318 PFKL; ATP-dependent 6-phosphofructokinase, liver type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 120764450 PFKM; ATP-dependent 6-phosphofructokinase, muscle type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 120750150 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 120759039 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 120755125 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 120761692 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 120755970 EXOSC1; exosome complex component CSL4 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 120761473 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024