+C Lipid biosynthesis protein KO #

  Lipid Biosynthesis Proteins - Homo sapiens (human)

% ! AFatty acid synthase B Animal type C 2194 FASN; fatty acid synthase K00665 FASN; fatty acid synthase, animal type [EC:2.3.1.85] B Yeast type B Bacteria type B Component type C 27349 MCAT; malonyl-CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] C 54995 OXSM; 3-oxoacyl-ACP synthase, mitochondrial K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] C 51144 HSD17B12; hydroxysteroid 17-beta dehydrogenase 12 K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] C 201562 HACD2; 3-hydroxyacyl-CoA dehydratase 2 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 401494 HACD4; 3-hydroxyacyl-CoA dehydratase 4 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 51495 HACD3; 3-hydroxyacyl-CoA dehydratase 3 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 9200 HACD1; 3-hydroxyacyl-CoA dehydratase 1 K10703 HACD; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] C 55825 PECR; peroxisomal trans-2-enoyl-CoA reductase K07753 PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38] C 9524 TECR; trans-2,3-enoyl-CoA reductase K10258 TER; very-long-chain enoyl-CoA reductase [EC:1.3.1.93] C 55301 OLAH; oleoyl-ACP hydrolase K01071 MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21] C 5538 PPT1; palmitoyl-protein thioesterase 1 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22] C 9374 PPT2; palmitoyl-protein thioesterase 2 K01074 PPT; palmitoyl-protein thioesterase [EC:3.1.2.22] C 10965 ACOT2; acyl-CoA thioesterase 2 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] C 122970 ACOT4; acyl-CoA thioesterase 4 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] C 641371 ACOT1; acyl-CoA thioesterase 1 K01068 ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] C 641372 ACOT6; acyl-CoA thioesterase 6 K11993 ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-] C 11332 ACOT7; acyl-CoA thioesterase 7 K17360 ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2] C 23597 ACOT9; acyl-CoA thioesterase 9 K17361 ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-] C 26027 ACOT11; acyl-CoA thioesterase 11 K12417 ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-] C 55856 ACOT13; acyl-CoA thioesterase 13 K17362 ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-] # ADesaturase B First C 6319 SCD; stearoyl-CoA desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] C 79966 SCD5; stearoyl-CoA desaturase 5 K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] B Omega C 3995 FADS3; fatty acid desaturase 3 K10225 FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-] B Front-end C 3992 FADS1; fatty acid desaturase 1 K10224 FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44] C 9415 FADS2; fatty acid desaturase 2 K10226 FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3] B Sphingolipid C 123099 DEGS2; delta 4-desaturase, sphingolipid 2 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5] C 8560 DEGS1; delta 4-desaturase, sphingolipid 1 K04712 DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5] B Other C 283985 FADS6; fatty acid desaturase 6 K12419 FADS6; fatty acid desaturase 6 [EC:1.14.19.-] # AElongase B LCFA B PUFA C 64834 ELOVL1; ELOVL fatty acid elongase 1 K10247 ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199] C 54898 ELOVL2; ELOVL fatty acid elongase 2 K10205 ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199] C 6785 ELOVL4; ELOVL fatty acid elongase 4 K10249 ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] C 60481 ELOVL5; ELOVL fatty acid elongase 5 K10244 ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199] C 79071 ELOVL6; ELOVL fatty acid elongase 6 K10203 ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199] C 79993 ELOVL7; ELOVL fatty acid elongase 7 K10250 ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199] B Unclassified C 83401 ELOVL3; ELOVL fatty acid elongase 3 K10248 ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199] # APolyketide synthase B Modular PKS B Component type # AAcyl-CoA ligase B Short/medium chain acyl-CoA ligase C 55902 ACSS2; acyl-CoA synthetase short chain family member 2 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 84532 ACSS1; acyl-CoA synthetase short chain family member 1 K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1] C 79611 ACSS3; acyl-CoA synthetase short chain family member 3 K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17] C 65985 AACS; acetoacetyl-CoA synthetase K01907 AACS; acetoacetyl-CoA synthetase [EC:6.2.1.16] C 116285 ACSM1; acyl-CoA synthetase medium chain family member 1 K23756 ACSM1; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:6.2.1.2] C 123876 ACSM2A; acyl-CoA synthetase medium chain family member 2A K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 142827 ACSM6; acyl-CoA synthetase medium chain family member 6 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 341392 ACSM4; acyl-CoA synthetase medium chain family member 4 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 348158 ACSM2B; acyl-CoA synthetase medium chain family member 2B K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 54988 ACSM5; acyl-CoA synthetase medium chain family member 5 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 6296 ACSM3; acyl-CoA synthetase medium chain family member 3 K01896 ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2] C 80221 ACSF2; acyl-CoA synthetase family member 2 K23617 ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2] B Long/very long chain acyl-CoA ligase C 2180 ACSL1; acyl-CoA synthetase long chain family member 1 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 2181 ACSL3; acyl-CoA synthetase long chain family member 3 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 2182 ACSL4; acyl-CoA synthetase long chain family member 4 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 23305 ACSL6; acyl-CoA synthetase long chain family member 6 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 51703 ACSL5; acyl-CoA synthetase long chain family member 5 K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 23205 ACSBG1; acyl-CoA synthetase bubblegum family member 1 K15013 ACSBG; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 81616 ACSBG2; acyl-CoA synthetase bubblegum family member 2 K15013 ACSBG; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3] C 10999 SLC27A4; solute carrier family 27 member 4 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] C 376497 SLC27A1; solute carrier family 27 member 1 K08745 SLC27A1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] C 11001 SLC27A2; solute carrier family 27 member 2 K08746 SLC27A2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3] C 11000 SLC27A3; solute carrier family 27 member 3 K08772 SLC27A3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-] B Unknown C 132949 AASDH; aminoadipate-semialdehyde dehydrogenase K00142 AASDH; acyl-CoA synthetase [EC:6.2.1.-] # AAcyl-AMP ligase B Fatty acyl-AMP ligase (FAAL) B Aryl-AMP ligase # APhospholipid acyltransferase B GPAT C 128966744 glycerol-3-phosphate acyltransferase 2, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C 150763 GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C 57678 GPAM; glycerol-3-phosphate acyltransferase, mitochondrial K00629 GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] C 137964 GPAT4; glycerol-3-phosphate acyltransferase 4 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] C 84803 GPAT3; glycerol-3-phosphate acyltransferase 3 K13506 GPAT3_4; glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] B LPAAT/LPLAT C 10554 AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1 K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51] C 10555 AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2 K13509 AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51] C 51099 ABHD5; abhydrolase domain containing 5, lysophosphatidic acid acyltransferase K13699 ABHD5; abhydrolase domain-containing protein 5 [EC:2.3.1.51] C 253558 LCLAT1; lysocardiolipin acyltransferase 1 K13513 LCLAT1; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51] C 6901 TAFAZZIN; tafazzin, phospholipid-lysophospholipid transacylase K13511 TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-] C 129642 MBOAT2; membrane bound glycerophospholipid O-acyltransferase 2 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] C 154141 MBOAT1; membrane bound glycerophospholipid O-acyltransferase 1 K13517 MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] C 56894 AGPAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3 K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] C 56895 AGPAT4; 1-acylglycerol-3-phosphate O-acyltransferase 4 K13523 AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] C 54947 LPCAT2; lysophosphatidylcholine acyltransferase 2 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] C 79888 LPCAT1; lysophosphatidylcholine acyltransferase 1 K13510 LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] C 254531 LPCAT4; lysophosphatidylcholine acyltransferase 4 K13512 LPCAT4; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-] C 9926 LPGAT1; lysophosphatidylglycerol acyltransferase 1 K13514 LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-] C 10162 LPCAT3; lysophosphatidylcholine acyltransferase 3 K13515 LPCAT3; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-] C 79143 MBOAT7; membrane bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7 K13516 MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-] # AOthers B Multifunctional type B Component type ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: December 11, 2024 #
Desaturase/elongase family classification based on Hashimoto et al. (2008)