+D GENES KO
#
KEGG Orthology (KO) - Halobacterium salinarum R1
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:hsl00010]
D OE_4691R glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D OE_3792F pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D OE_2020F fbp; fructose-1,6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D OE_2019F fba1; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D OE_1472F fba2; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase / fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D OE_2500R tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D OE_1154F gap; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D OE_2745R pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D OE_3653R gpmI; phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D OE_2640F eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D OE_1495R pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D OE_1500R ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D OE_3712R oxdhA2; probable branched-chain amino acid dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4113F oxdhA1; 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4114F oxdhB; 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D OE_4115F dsa; dihydrolipoamide S-acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D OE_1711R korA; oxoglutarate--ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D OE_1710R korB; oxoglutarate--ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2372F acdA; acetate--CoA ligase (ADP-forming) K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_2367F aldH3; aldehyde dehydrogenase K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
C 00020 Citrate cycle (TCA cycle) [PATH:hsl00020]
D OE_3934R citZ; citrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D OE_3634F icd; isocitrate dehydrogenase (NADP) K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_1711R korA; oxoglutarate--ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D OE_1710R korB; oxoglutarate--ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D OE_3196F sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D OE_3195F sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D OE_4211F cat; probable succinyl-CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D OE_2865R sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D OE_2866R sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D OE_2868R sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D OE_2867R sdhD; succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D OE_2935R fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D OE_3712R oxdhA2; probable branched-chain amino acid dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4113F oxdhA1; 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4114F oxdhB; 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D OE_4115F dsa; dihydrolipoamide S-acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:hsl00030]
D OE_3792F pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D OE_1209F GalE family epimerase/dehydratase K19243 azf; NAD+ dependent glucose-6-phosphate dehydrogenase [EC:1.1.1.388]
D OE_4581F gndA; 6-phosphogluconate dehydrogenase (decarboxylating) K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
D OE_4185F rpiA; ribose-5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D OE_3616F deoC; deoxyribose-phosphate aldolase K01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]
D OE_2318R pmm3; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_3606R suk1; sugar kinase K26208 E2.7.1.239; alpha-D-ribose-1-phosphate 5-kinase (ATP) [EC:2.7.1.239]
D OE_3610R ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming) K18237 K18237; ribose 1,5-bisphosphate isomerase [EC:5.3.1.29]
D OE_4085R prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D OE_2367F aldH3; aldehyde dehydrogenase K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
D OE_1669F gdh; glucose 1-dehydrogenase K22969 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]
D OE_2509R GMC family oxidoreductase K19813 gdh; glucose dehydrogenase [EC:1.1.5.9]
D OE_1664R gnaD; D-gluconate dehydratase K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D OE_1266R kdgK; 2-keto-3-deoxygluconate kinase K00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]
D OE_2019F fba1; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D OE_1472F fba2; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase / fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D OE_2020F fbp; fructose-1,6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
C 00040 Pentose and glucuronate interconversions
D OE_1077R aglM2; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_2524R aglM1; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
C 00051 Fructose and mannose metabolism [PATH:hsl00051]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_4022R manC; mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D OE_2020F fbp; fructose-1,6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D OE_2019F fba1; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D OE_1472F fba2; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase / fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D OE_2500R tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:hsl00052]
D OE_2110R GalE family epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_4691R glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D OE_1664R gnaD; D-gluconate dehydratase K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
C 00053 Ascorbate and aldarate metabolism [PATH:hsl00053]
D OE_1077R aglM2; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_2524R aglM1; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00500 Starch and sucrose metabolism [PATH:hsl00500]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_4691R glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D OE_3792F pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00620 Pyruvate metabolism [PATH:hsl00620]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D OE_1711R korA; oxoglutarate--ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D OE_1710R korB; oxoglutarate--ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D OE_3712R oxdhA2; probable branched-chain amino acid dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4113F oxdhA1; 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4114F oxdhB; 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D OE_4115F dsa; dihydrolipoamide S-acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_1495R pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D OE_3177F pccA2; propionyl-CoA carboxylase biotin carboxylase component K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4211F cat; probable succinyl-CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D OE_5189F 3-oxoacid CoA-transferase K01026 pct; propionate CoA-transferase [EC:2.8.3.1]
D OE_2372F acdA; acetate--CoA ligase (ADP-forming) K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D OE_2610F glyoxalase domain protein K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D OE_3308F maeB; malate dehydrogenase (oxaloacetate-decarboxylating) K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D OE_2935R fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D OE_4169F ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D OE_1500R ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:hsl00630]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D OE_3934R citZ; citrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_1718R mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D OE_3177F pccA2; propionyl-CoA carboxylase biotin carboxylase component K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D OE_3175F pccB2; propionyl-CoA carboxylase carboxyltransferase component K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D OE_3176F uncharacterized protein K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D OE_2005F mmcB; methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit) K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D OE_1721R mmcA2; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_1972F mmcA1; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_4206F mamB; methylaspartate mutase large subunit K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D OE_4204F mamA; methylaspartate mutase small subunit K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
D OE_4207F mal; methylaspartate ammonia-lyase K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D OE_3121R HAD superfamily hydrolase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D OE_3492R HAD superfamily hydrolase K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D OE_2060R phosphoglycolate phosphatase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D OE_3922R glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D OE_3036F glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D OE_3275R gcvP1; glycine cleavage system protein P alpha subunit K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D OE_3274R gcvP2; glycine cleavage system protein P beta subunit K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D OE_3278R gcvT; glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_4705R homolog to glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_3277R gcvH; glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein
D OE_5160F gldA1; glycerol dehydrogenase K26209 K26209; glycolaldehyde reductase [EC:1.1.1.-]
D OE_2727R HAD superfamily hydrolase K26210 E3.1.3.109; ribulose-1,5-bisphosphate 5-phosphatase [EC:3.1.3.109]
D OE_2725R class II aldolase (homolog to L-fuculose-phosphate aldolase) K01636 K01636; ribulose 1-phosphate aldolase [EC:4.1.2.-]
D OE_3735F purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
C 00640 Propanoate metabolism [PATH:hsl00640]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_5189F 3-oxoacid CoA-transferase K01026 pct; propionate CoA-transferase [EC:2.8.3.1]
D OE_2372F acdA; acetate--CoA ligase (ADP-forming) K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D OE_3177F pccA2; propionyl-CoA carboxylase biotin carboxylase component K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D OE_3175F pccB2; propionyl-CoA carboxylase carboxyltransferase component K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D OE_3176F uncharacterized protein K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D OE_3168R pyridoxal phosphate-dependent aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D OE_1718R mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D OE_2005F mmcB; methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit) K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D OE_1721R mmcA2; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_1972F mmcA1; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_3195F sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D OE_3196F sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D OE_3934R citZ; citrate synthase K01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]
C 00650 Butanoate metabolism [PATH:hsl00650]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2015R hbd1; 3-hydroxyacyl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D OE_1641R fadA2; enoyl-CoA hydratase K01715 crt; enoyl-CoA hydratase [EC:4.2.1.17]
D OE_2865R sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D OE_2866R sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D OE_2868R sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D OE_2867R sdhD; succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D OE_3168R pyridoxal phosphate-dependent aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D OE_2190R aldH4; aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D OE_4211F cat; probable succinyl-CoA transferase K18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D OE_1711R korA; oxoglutarate--ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D OE_1710R korB; oxoglutarate--ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D OE_3296F hmgB; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00660 C5-Branched dibasic acid metabolism [PATH:hsl00660]
D OE_3195F sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D OE_3196F sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D OE_4209F maoC1; MaoC domain protein K18290 ich-Y; itaconyl-CoA hydratase [EC:4.2.1.56]
D OE_4207F mal; methylaspartate ammonia-lyase K04835 mal; methylaspartate ammonia-lyase [EC:4.3.1.2]
D OE_4206F mamB; methylaspartate mutase large subunit K19268 glmE; methylaspartate mutase epsilon subunit [EC:5.4.99.1]
D OE_4204F mamA; methylaspartate mutase small subunit K01846 glmS; methylaspartate mutase sigma subunit [EC:5.4.99.1]
C 00562 Inositol phosphate metabolism [PATH:hsl00562]
D OE_2970R suhB; probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D OE_2500R tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:hsl00190]
D OE_1953F nuoA; NADH dehydrogenase-like complex subunit A K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D OE_1954F nuoB; NADH dehydrogenase-like complex subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D OE_1956F nuoCD; NADH dehydrogenase-like complex subunit CD K13378 nuoCD; NADH-quinone oxidoreductase subunit C/D [EC:7.1.1.2]
D OE_1957F nuoH; NADH dehydrogenase-like complex subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D OE_1958F nuoI; NADH dehydrogenase-like complex subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D OE_1959F nuoJ1; NADH dehydrogenase-like complex subunit J1 K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D OE_1960F nuoJ2; NADH dehydrogenase-like complex subunit J2 K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D OE_1963F nuoK; NADH dehydrogenase-like complex subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D OE_1964F nuoL; NADH dehydrogenase-like complex subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D OE_1965F nuoM; NADH dehydrogenase-like complex subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D OE_1967F nuoN; NADH dehydrogenase-like complex subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D OE_2307F ndh; probable NADH dehydrogenase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D OE_2865R sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D OE_2866R sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D OE_2868R sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D OE_2867R sdhD; succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D OE_1989F ctaB; protoheme IX geranylgeranyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D OE_1984F coxC1; cox-type terminal oxidase subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D OE_1979R coxA1; cox-type terminal oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D OE_4070R cbaA; ba3-type terminal oxidase subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D OE_1988R coxB1; cox-type terminal oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D OE_4071R cbaB; ba3-type terminal oxidase subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D OE_3306R ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D OE_6185F cydA2; cytochrome bd ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D OE_7065F cydA1; cytochrome bd ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D OE_6186F cydB2; cytochrome bd ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D OE_7066F cydB1; cytochrome bd ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D OE_3985R atpA; A-type ATP synthase subunit A K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D OE_3984R atpB; A-type ATP synthase subunit B K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D OE_3987R atpC; A-type ATP synthase subunit C K02119 ATPVC; V/A-type H+/Na+-transporting ATPase subunit C
D OE_3978R atpD; A-type ATP synthase subunit D K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D OE_3988R atpE; A-type ATP synthase subunit E K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D OE_3986R atpF; A-type ATP synthase subunit F K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D OE_3992R atpH; A-type ATP synthase subunit H K02107 ATPVG; V/A-type H+/Na+-transporting ATPase subunit G/H
D OE_3991R atpI; A-type ATP synthase subunit I K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D OE_3989R atpK; A-type ATP synthase subunit K K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D OE_1407F ipp; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:hsl00710]
D OE_2745R pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D OE_1154F gap; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D OE_2019F fba1; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D OE_2020F fbp; fructose-1,6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D OE_4185F rpiA; ribose-5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D OE_2500R tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D OE_4169F ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D OE_3308F maeB; malate dehydrogenase (oxaloacetate-decarboxylating) K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:hsl00720]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D OE_1500R ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D OE_4169F ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D OE_2935R fumC; fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D OE_2865R sdhA; succinate dehydrogenase subunit A K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D OE_2866R sdhB; succinate dehydrogenase subunit B K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D OE_2868R sdhC; succinate dehydrogenase subunit C K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D OE_2867R sdhD; succinate dehydrogenase subunit D K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D OE_3196F sucD; succinate--CoA ligase (ADP-forming) alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D OE_3195F sucC; succinate--CoA ligase (ADP-forming) beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D OE_2871F hbd2; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_1711R korA; oxoglutarate--ferredoxin oxidoreductase alpha subunit K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D OE_1710R korB; oxoglutarate--ferredoxin oxidoreductase beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D OE_3634F icd; isocitrate dehydrogenase (NADP) K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D OE_1718R mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D OE_1721R mmcA2; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_1972F mmcA1; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_2005F mmcB; methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit) K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D OE_3038F folD; methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:hsl00680]
D OE_3036F glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D OE_2640F eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D OE_4169F ppcA; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D OE_2019F fba1; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D OE_1472F fba2; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase / fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D OE_2020F fbp; fructose-1,6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D OE_3383R mch; probable methenyltetrahydrofolate cyclohydrolase K01499 mch; methenyltetrahydromethanopterin cyclohydrolase [EC:3.5.4.27]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D OE_1500R ppsA; phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D OE_3653R gpmI; phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D OE_4408F serA1; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D OE_4405R serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D OE_3723R cofH; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2 K11781 cofH; 5-amino-6-(D-ribitylamino)uracil---L-tyrosine 4-hydroxyphenyl transferase [EC:2.5.1.147]
D OE_3722F cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 K11780 cofG; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase [EC:4.3.1.32]
D OE_3721F cofC; 2-phospho-L-lactate guanylyltransferase K14941 cofC; 2-phospho-L-lactate/phosphoenolpyruvate guanylyltransferase [EC:2.7.7.68 2.7.7.105]
D OE_3057F cofD; 2-phospho-L-lactate transferase K11212 cofD; LPPG:FO 2-phospho-L-lactate transferase [EC:2.7.8.28]
D OE_4628R cofE; coenzyme F420:L-glutamate ligase K12234 cofE; coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]
D OE_1498R mfnA; L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
C 00910 Nitrogen metabolism [PATH:hsl00910]
D OE_1270F gdhA3; glutamate dehydrogenase (NAD) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_1943F gdhA1; glutamate dehydrogenase (NADP) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_2728R gdhA2; glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_3922R glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D OE_5206R arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D OE_2243R cynT; carbonic anhydrase K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:hsl00920]
D OE_1684F homolog to sulfate adenylyltransferase small subunit K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D OE_4384R DoxX domain protein K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D OE_4355R tssA1; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D OE_4356F tssA2; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D OE_3122F cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D OE_2860R cysK2; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D OE_4397F metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D OE_2223F dmsA; dimethylsulfoxide reductase subunit A K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D OE_2225F dmsB; dimethylsulfoxide reductase subunit B K00184 dmsB; dimethyl sulfoxide reductase iron-sulfur subunit
D OE_2227F dmsC; dimethylsulfoxide reductase subunit C K00185 dmsC; dimethyl sulfoxide reductase membrane subunit
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:hsl00061]
D OE_3177F pccA2; propionyl-CoA carboxylase biotin carboxylase component K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D OE_4021F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_4695F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_2912F acs3; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_3891R acs5; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:hsl00071]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D OE_4500R acd6; glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D OE_2912F acs3; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_3891R acs5; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00074 Mycolic acid biosynthesis
C 00100 Steroid biosynthesis [PATH:hsl00100]
D OE_2014F fdfT; squalene synthase K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:hsl00561]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_3762R glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D OE_1906R gth2; probable glycosyltransferase, type 1 K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
C 00564 Glycerophospholipid metabolism [PATH:hsl00564]
D OE_2553R glpA2; glycerol-3-phosphate dehydrogenase subunit A K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D OE_3763F glpA1; glycerol-3-phosphate dehydrogenase subunit A K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D OE_3764F glpB; glycerol-3-phosphate dehydrogenase subunit B K00112 glpB; glycerol-3-phosphate dehydrogenase subunit B [EC:1.1.5.3]
D OE_3765F glpC; glycerol-3-phosphate dehydrogenase subunit C K00113 glpC; glycerol-3-phosphate dehydrogenase subunit C
D OE_3594R glpQ; glycerophosphodiester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D OE_4164F psd; homolog to phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D OE_2491F pgsA1; CDP-alcohol 1-archaetidyltransferase K00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D OE_2142R phospholipase D domain protein K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
D OE_1602F gldA2; glycerol-1-phosphate dehydrogenase (NAD(P)) K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D OE_1398R pcrB1; (S)-3-O-geranylgeranylglyceryl phosphate synthase 1 K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D OE_3699R pcrB2; (S)-3-O-geranylgeranylglyceryl phosphate synthase 2 K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D OE_1921R ubiA2; (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D OE_3954R UPF0290 family protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D OE_2155R pgsA3; CDP-alcohol 1-archaetidyltransferase K19665 pssA; archaetidylserine synthase [EC:2.7.8.38]
D OE_1699R geranylgeranyl reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism [PATH:hsl00592]
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:hsl00230]
D OE_3752R NUDIX family hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D OE_4621F NUDIX family hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D OE_2318R pmm3; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K22199 ppm; phosphopentomutase [EC:5.4.2.7]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_4085R prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D OE_3139R purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D OE_2864F purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D OE_1620R purNH; phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D OE_2274R purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D OE_3732R purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D OE_3731R purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D OE_2292F purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D OE_1951F purK; 5-(carboxyamino)imidazole ribonucleotide synthase K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D OE_1952F purE; N5-carboxyaminoimidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D OE_3724F purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D OE_1623F purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D OE_4329F purO; inosine-5'-monophosphate cyclohydrolase, archaeal-type K11176 purO; IMP cyclohydrolase [EC:3.5.4.10]
D OE_1840R apt1; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D OE_2782F surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D OE_2458R guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D OE_2667F ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D OE_3863R ham1; non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D OE_1363F guaAa1; GMP synthase (glutamine-hydrolyzing) subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D OE_3571R guaAb; GMP synthase (glutamine-hydrolyzing) subunit B K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D OE_4502R guaAa2; glutamine amidotransferase (homolog to GMP synthase subunit A) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D OE_3603R udp3; uridine phosphorylase K26212 K26212; guanosine phosphorylase [EC:2.4.2.15]
D OE_3328R nrdJ; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OE_4346R nrdA1; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OE_4345R nrdB1; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D OE_2856F cyaB; adenylate cyclase K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D OE_2579F purA; adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D OE_3425F adk1; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D OE_2506R adk2; probable adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D OE_3620R hit2; histidine triad family protein (homolog to bis(5'-nucleosyl)-tetraphosphatase) K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D OE_5206R arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
C 00240 Pyrimidine metabolism [PATH:hsl00240]
D OE_3554F carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D OE_3556R carA; carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D OE_5201F pyrB; aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D OE_5202F pyrI; aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D OE_4558R pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D OE_4508R pyrD; dihydroorotate dehydrogenase (quinone) K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D OE_3953R pyrE2; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D OE_3363F pyrF; orotidine-5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D OE_3823F pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D OE_2667F ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D OE_3572R pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D OE_3429F cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D OE_2749F udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48]
D OE_2782F surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D OE_2311R udp2; uridine phosphorylase K00757 udp; uridine phosphorylase [EC:2.4.2.3]
D OE_4234R upp; uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D OE_2313R cdd; cytidine deaminase K01489 cdd; cytidine deaminase [EC:3.5.4.5]
D OE_1384F dcd1; dCTP deaminase (dUMP-forming) K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D OE_3328R nrdJ; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OE_4346R nrdA1; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OE_4345R nrdB1; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D OE_3715R tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D OE_4610R dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D OE_3159R tdk; thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
D OE_2898R thyX; thymidylate synthase ThyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:hsl00250]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_3646F nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D OE_3633R ansA; asparaginase family protein K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D OE_2278F asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D OE_4121R ala; alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
D OE_4420R argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D OE_4419R argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D OE_2579F purA; adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D OE_1623F purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D OE_5201F pyrB; aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D OE_5202F pyrI; aspartate carbamoyltransferase regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D OE_3168R pyridoxal phosphate-dependent aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D OE_2190R aldH4; aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D OE_1270F gdhA3; glutamate dehydrogenase (NAD) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_1943F gdhA1; glutamate dehydrogenase (NADP) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_2728R gdhA2; glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_3922R glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D OE_3554F carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D OE_3556R carA; carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D OE_3731R purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D OE_1013R glmS; glutamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D OE_3139R purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:hsl00260]
D OE_4333R lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D OE_3063F asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D OE_4722R hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D OE_3531R thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D OE_1807R thrC2; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D OE_3941F thrC3; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D OE_4412R thrC1; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D OE_4436R ltaE; threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48]
D OE_3036F glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D OE_3653R gpmI; phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D OE_4408F serA1; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D OE_4405R serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D OE_3275R gcvP1; glycine cleavage system protein P alpha subunit K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D OE_3274R gcvP2; glycine cleavage system protein P beta subunit K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D OE_3278R gcvT; glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_4705R homolog to glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_3277R gcvH; glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein
D OE_2173F metB2; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_2681F metB1; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_3931R ilvA; threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D OE_1471F trpA; tryptophan synthase alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D OE_1470F trpB; tryptophan synthase beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D OE_5094F dat; diaminobutyrate--2-oxoglutarate aminotransferase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D OE_5095F bdb; diaminobutyrate decarboxylase K13745 ddc; L-2,4-diaminobutyrate decarboxylase [EC:4.1.1.86]
C 00270 Cysteine and methionine metabolism [PATH:hsl00270]
D OE_3122F cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D OE_2860R cysK2; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D OE_2173F metB2; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_2681F metB1; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_1916F cysK1; cysteine synthase K17216 mccA; cystathionine beta-synthase (O-acetyl-L-serine) [EC:2.5.1.134]
D OE_2668R metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D OE_2857F mat; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D OE_2730R probable nucleoside deaminase (cytosine/guanine deaminase) K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D OE_4157F mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D OE_4159F ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D OE_4333R lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D OE_3063F asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D OE_4722R hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D OE_3531R thrB; homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D OE_4397F metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D OE_4398F metY; O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D OE_1574F pabC; aminodeoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_3959R ilvE2; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_4355R tssA1; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D OE_4356F tssA2; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D OE_4323F mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D OE_4408F serA1; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:hsl00280]
D OE_1574F pabC; aminodeoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_3959R ilvE2; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D OE_3177F pccA2; propionyl-CoA carboxylase biotin carboxylase component K11263 bccA; acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
D OE_3175F pccB2; propionyl-CoA carboxylase carboxyltransferase component K19312 pccB; acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D OE_3176F uncharacterized protein K22568 pccX; acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
D OE_1718R mce; methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D OE_2005F mmcB; methylmalonyl-CoA mutase subunit B (cobalamin-binding subunit) K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D OE_1721R mmcA2; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_1972F mmcA1; methylmalonyl-CoA mutase subunit A K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_3296F hmgB; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:hsl00290]
D OE_3931R ilvA; threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D OE_1574F pabC; aminodeoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_3959R ilvE2; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00300 Lysine biosynthesis [PATH:hsl00300]
D OE_4722R hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D OE_4333R lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D OE_3063F asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
C 00310 Lysine degradation [PATH:hsl00310]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_4500R acd6; glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2190R aldH4; aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:hsl00220]
D OE_5205R arcB; ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D OE_4420R argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D OE_4419R argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D OE_5208R arcA; arginine deiminase K01478 arcA; arginine deiminase [EC:3.5.3.6]
D OE_3731R purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D OE_3922R glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D OE_3554F carB; carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D OE_3556R carA; carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D OE_5206R arcC; carbamate kinase K00926 arcC; carbamate kinase [EC:2.7.2.2]
D OE_1270F gdhA3; glutamate dehydrogenase (NAD) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_1943F gdhA1; glutamate dehydrogenase (NADP) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_2728R gdhA2; glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00330 Arginine and proline metabolism [PATH:hsl00330]
D OE_1203F cre1; creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D OE_3488R cre2; creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D OE_3803R pdaD; pyruvoyl-dependent arginine decarboxylase K02626 pdaD; arginine decarboxylase [EC:4.1.1.19]
D OE_3486R speB; agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_3955F fadM; proline dehydrogenase K00318 PRODH; proline dehydrogenase [EC:1.5.5.2]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:hsl00340]
D OE_4152R hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D OE_4641R hisE; phosphoribosyl-ATP pyrophosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D OE_4199R hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D OE_4218F hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D OE_3913F hisH; imidazoleglycerol-phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D OE_2268R hisF; imidazoleglycerol-phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D OE_4220F hisB; imidazoleglycerol-phosphate dehydratase K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D OE_2507R hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D OE_3071F hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D OE_2739F hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]
D OE_2734F hutU; urocanate hydratase K01712 hutU; urocanate hydratase [EC:4.2.1.49]
D OE_2738F hutI; imidazolonepropionase K01468 hutI; imidazolonepropionase [EC:3.5.2.7]
D OE_2736F hutG; formimidoylglutamase K01479 hutG; formiminoglutamase [EC:3.5.3.8]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00350 Tyrosine metabolism [PATH:hsl00350]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_2507R hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D OE_1498R mfnA; L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D OE_2190R aldH4; aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism [PATH:hsl00360]
D OE_2015R hbd1; 3-hydroxyacyl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_2507R hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D OE_5186R katG; catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C 00380 Tryptophan metabolism [PATH:hsl00380]
D OE_2332F kynU; kynureninase K01556 KYNU; kynureninase [EC:3.7.1.3]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_4500R acd6; glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_4331R tnaA; tryptophanase K01667 tnaA; tryptophanase [EC:4.1.99.1]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_5186R katG; catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:hsl00400]
D OE_1472F fba2; 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase / fructose-bisphosphate aldolase K16306 K16306; fructose-bisphosphate aldolase / 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [EC:4.1.2.13 2.2.1.10]
D OE_1475F aroB; 3-dehydroquinate synthase, type II K11646 K11646; 3-dehydroquinate synthase II [EC:1.4.1.24]
D OE_1477R aroD; 3-dehydroquinate dehydratase K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D OE_1565F aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D OE_2785R aroK; shikimate kinase, archaeal-type K00891 aroK; shikimate kinase [EC:2.7.1.71]
D OE_2762R aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D OE_2761R aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D OE_1568F pabB; aminodeoxychorismate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D OE_3332R trpE1; anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D OE_3331R trpG1; anthranilate synthase component 2 K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D OE_3334R trpD1; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D OE_3691F trpD2; probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D OE_3333R trpF; N-(5'-phosphoribosyl)anthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D OE_1469F trpC; indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D OE_1471F trpA; tryptophan synthase alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D OE_1470F trpB; tryptophan synthase beta subunit K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D OE_2784R aroQ; chorismate mutase K04093 pheA1; chorismate mutase [EC:5.4.99.5]
D OE_2770F tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D OE_4117F pheA; prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_2507R hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:hsl00410]
D OE_1498R mfnA; L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D OE_3168R pyridoxal phosphate-dependent aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_1394R 4-phosphopantoate--beta-alanine ligase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
C 00430 Taurine and hypotaurine metabolism
D OE_4121R ala; alanine dehydrogenase K19244 ala; alanine dehydrogenase [EC:1.4.1.1]
C 00440 Phosphonate and phosphinate metabolism
D OE_3881R beta-lactamase domain protein K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:hsl00450]
D OE_2668R metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D OE_2173F metB2; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_2681F metB1; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_4463F sufS; cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D OE_2805R trxB2; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D OE_1496R metS; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:hsl00460]
D OE_3633R ansA; asparaginase family protein K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D OE_3036F glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:hsl00470]
D OE_3731R purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D OE_3585R DUF1611 family protein K26272 dgcN; D-glutamate N-acetyltransferase [EC:2.3.1.312]
D OE_3584R homolog to dipeptide epimerase K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
C 00480 Glutathione metabolism [PATH:hsl00480]
D OE_2998R gshA; glutamate--cysteine ligase K06048 gshA; glutamate---cysteine ligase / carboxylate-amine ligase [EC:6.3.2.2 6.3.-.-]
D OE_1260R merA; probable oxidoreductase (homolog to mercury(II) reductase / dihydrolipoamide dehydrogenase) K03423 E1.8.1.13; bis-gamma-glutamylcystine reductase [EC:1.8.1.13]
D OE_3634F icd; isocitrate dehydrogenase (NADP) K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D OE_4581F gndA; 6-phosphogluconate dehydrogenase (decarboxylating) K00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]
B
B 09107 Glycan biosynthesis and metabolism
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:hsl00520]
D OE_1016R graD2; sugar nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D OE_1115F GalE family epimerase/dehydratase K02473 wbpP; UDP-N-acetylglucosamine/UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase [EC:5.1.3.7 5.1.3.45]
D OE_2201F chiA1; chitinase K01183 E3.2.1.14; chitinase [EC:3.2.1.14]
D OE_2205F chiA2; chitinase K01183 E3.2.1.14; chitinase [EC:3.2.1.14]
D OE_1013R glmS; glutamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D OE_3792F pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D OE_4691R glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_1077R aglM2; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_2524R aglM1; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_2110R GalE family epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D OE_4022R manC; mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D OE_1014R graD5; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1078F aglF1; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1114F graD3; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1578F graD1; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_2530F aglF2; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
C 00541 Biosynthesis of various nucleotide sugars [PATH:hsl00541]
D OE_1016R graD2; sugar nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D OE_1115F GalE family epimerase/dehydratase K02473 wbpP; UDP-N-acetylglucosamine/UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase [EC:5.1.3.7 5.1.3.45]
D OE_1077R aglM2; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_2524R aglM1; UDP-glucose 6-dehydrogenase AglM K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D OE_1014R graD5; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1078F aglF1; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1114F graD3; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1578F graD1; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_2530F aglF2; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_4022R manC; mannose-1-phosphate guanylyltransferase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:hsl00543]
D OE_3122F cysE; serine O-acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:hsl00730]
D OE_2057F thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D OE_4654F thiDN; phosphomethylpyrimidine kinase / phosphomethylpyrimidine phosphate kinase / thiamine-phosphate synthase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D OE_2858F thiI; ThiI-type thiouridine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D OE_4651F thi4; thiamine thiazole synthase K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D OE_3818F thiL; thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D OE_5192R aph; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D OE_3425F adk1; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:hsl00740]
D OE_2472F gch3a; GTP cyclohydrolase III K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D OE_2492F gch3b; GTP cyclohydrolase III K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D OE_2802F ribG; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D OE_3963R ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D OE_1946R ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D OE_4683F ribE; riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D OE_3964R ribK; riboflavin kinase, CTP-dependent K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D OE_2139R ribL; FAD synthase K14656 ribL; FAD synthetase [EC:2.7.7.2]
D OE_3752R NUDIX family hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D OE_4621F NUDIX family hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C 00750 Vitamin B6 metabolism [PATH:hsl00750]
D OE_1807R thrC2; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D OE_3941F thrC3; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D OE_4412R thrC1; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D OE_3524F pdxS; pyridoxal biosynthesis lyase PdxS K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D OE_4644R pdxT; pyridoxine biosynthesis protein glutaminase component K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:hsl00760]
D OE_3646F nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D OE_3644F nadA; quinolinate synthase A K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D OE_3648F nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D OE_4565F pncB; nicotinate phosphoribosyltransferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D OE_2782F surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D OE_1462R nadM; nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D OE_3843F nadE; NAD synthase, ammonia-dependent K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D OE_1550F CinA C-terminal domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D OE_1865F nadK2; probable NAD kinase (polyphosphate/ATP) K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D OE_3671F nadK1; probable NAD kinase (polyphosphate/ATP) K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D OE_2190R aldH4; aldehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:hsl00770]
D OE_3119R panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D OE_2078R panE; 2-dehydropantoate 2-reductase K00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]
D OE_1396R pantoate kinase K06982 pok; pantoate kinase [EC:2.7.1.169]
D OE_1394R 4-phosphopantoate--beta-alanine ligase K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D OE_1856R coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D OE_2992R coaD; phosphopantetheine adenylyltransferase K02201 E2.7.7.3B; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D OE_3871R UPF0218 family protein K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D OE_1574F pabC; aminodeoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_3959R ilvE2; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_1498R mfnA; L-tyrosine decarboxylase K18933 mfnA; tyrosine decarboxylase / aspartate 1-decarboxylase [EC:4.1.1.25 4.1.1.11]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:hsl00780]
D OE_4021F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_4695F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_3186F birA1; HTH domain protein / biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:hsl00785]
D OE_4111F lipA; lipoate synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D OE_4559R lpl3; homolog to lipoate-protein ligase K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D OE_1302F lpl1; lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D OE_5139F lpl2; lipoate-protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_3712R oxdhA2; probable branched-chain amino acid dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4113F oxdhA1; 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D OE_4114F oxdhB; 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D OE_4115F dsa; dihydrolipoamide S-acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D OE_3275R gcvP1; glycine cleavage system protein P alpha subunit K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D OE_3274R gcvP2; glycine cleavage system protein P beta subunit K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D OE_3278R gcvT; glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_4705R homolog to glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_3277R gcvH; glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:hsl00790]
D OE_5192R aph; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D OE_2921R folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D OE_1615R folCP; folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase K24102 folCP; dihydrofolate synthase / dihydropteroate synthase [EC:6.3.2.12 2.5.1.15]
D OE_2495F PtpS family protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D OE_5198R queD; 6-carboxy-5,6,7,8-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D OE_3495R cad; probable pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D OE_5197R queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D OE_5195R queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D OE_3673F mptA; GTP cyclohydrolase MptA K17488 mptA; GTP cyclohydrolase IV [EC:3.5.4.39]
D OE_1207R mptD; dihydroneopterin aldolase, archaeal-type K09739 mptD; dihydroneopterin aldolase [EC:4.1.2.25]
D OE_2919R mptE; 6-hydroxymethyl-7,8-dihydropterine pyrophosphokinase MptE K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D OE_1142F moaA; probable cyclic pyranopterin monophosphate synthase K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D OE_2825F moaC; probable cyclic pyranopterin monophosphate synthase accessory protein K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D OE_1139F moaE; molybdopterin synthase catalytic subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D OE_3565F moaB; molybdopterin adenylyltransferase K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D OE_1143R moeA2; molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D OE_1146R moeA1; molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D OE_2217R mobA; molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:hsl00670]
D OE_3038F folD; methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D OE_3036F glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D OE_1620R purNH; phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase K01492 purNH; phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
D OE_3278R gcvT; glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_4705R homolog to glycine cleavage system protein T K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D OE_2898R thyX; thymidylate synthase ThyX K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D OE_3735F purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D OE_3566F probable COG0212-type thiamine metabolism protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
D OE_2857F mat; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D OE_4159F ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D OE_3275R gcvP1; glycine cleavage system protein P alpha subunit K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D OE_3274R gcvP2; glycine cleavage system protein P beta subunit K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_3277R gcvH; glycine cleavage system protein H K02437 gcvH; glycine cleavage system H protein
D OE_2173F metB2; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_2681F metB1; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:hsl00860]
D OE_2652F gltS; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D OE_3496R hemA; glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D OE_4268F hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D OE_4262F hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D OE_4276F hemC; hydroxymethylbilane synthase (porphobilinogen deaminase) K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D OE_4281F hemD; uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D OE_3832F hemQ; heme-binding protein HemQ K25033 chdC; hydrogen peroxide-dependent heme synthase [EC:1.3.98.5]
D OE_4277F sirA; uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D OE_3498R sirC; precorrin-2 oxidase / ferrochelatase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D OE_3500R ahbB; siroheme decarboxylase AhbB K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D OE_3689R ahbA; siroheme decarboxylase AhbA K22225 ahbAB; siroheme decarboxylase [EC:4.1.1.111]
D OE_2697R ahbC; Fe-coproporphyrin synthase AhbC K22226 ahbC; Fe-coproporphyrin III synthase
D OE_2700F ahbD; alternative heme synthase AhbD K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D OE_1989F ctaB; protoheme IX geranylgeranyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D OE_3306R ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D OE_2585R cbiX2; sirohydrochlorin cobaltochelatase K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D OE_3221F cbiX1; sirohydrochlorin cobaltochelatase K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D OE_3209F cbiL; cobalt-factor-II C20-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D OE_3214F cbiH1; cobalt-factor-III C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D OE_3216F cbiH2; cobalt-factor-III C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D OE_3212F cbiF; cobalt-precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D OE_3213F cbiG; cobalt-precorrin-5A hydrolase K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D OE_3207F cbiT; cobalt-precorrin-6B C15-methyltransferase (decarboxylating) K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D OE_3238F cbiE; cobalt-precorrin-7 C5-methyltransferase K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D OE_3237F cbiC; cobalt-precorrin-8 methylmutase K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D OE_3243F cbiA; cobyrinate a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D OE_3230F cobN; ATP-dependent cobaltochelatase subunit CobN K02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]
D OE_3203R pduO; ATP:cob(I)alamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D OE_3245F cobA; cob(I)alamin adenosyltransferase K19221 cobA; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D OE_3246F cbiP; adenosylcobyric acid synthase K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D OE_3253F cbiB; adenosylcobinamide-phosphate synthase K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D OE_3261F cbiZ; adenosylcobinamide amidohydrolase K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90]
D OE_3257F cobY; adenosylcobinamide-phosphate guanylyltransferase K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D OE_3255F cobS; adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D OE_3259F cobD; L-threonine-O-3-phosphate decarboxylase K04720 cobD; threonine-phosphate decarboxylase [EC:4.1.1.81]
D OE_3229R chlID; ATP-dependent cobaltochelatase subunit ChlID K03404 chlD; magnesium chelatase subunit D [EC:6.6.1.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:hsl00130]
D OE_2566R menF; isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
D OE_2563R menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase K02551 menD; 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:2.2.1.9]
D OE_2555R menE; O-succinylbenzoate--CoA ligase K01911 menE; o-succinylbenzoate---CoA ligase [EC:6.2.1.26]
D OE_2561R menB; naphthoate synthase K01661 menB; naphthoate synthase [EC:4.1.3.36]
D OE_2559R menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:hsl00900]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_3296F hmgB; hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D OE_3637R hmgA; hydroxymethylglutaryl-CoA reductase (NADPH) K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D OE_2645F mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D OE_1893F mvaD; phosphomevalonate decarboxylase K17942 pmd; phosphomevalonate decarboxylase [EC:4.1.1.99]
D OE_2647F isopentenyl phosphate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D OE_3560F idiA; isopentenyl-diphosphate delta-isomerase, type I K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D OE_6213R idiB2; isopentenyl-diphosphate delta-isomerase, type II K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D OE_7093R idiB1; isopentenyl-diphosphate delta-isomerase, type II K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D OE_2650F idsA1; bifunctional short chain isoprenyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D OE_4010F idsA2; bifunctional short chain isoprenyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D OE_3505R uppS2; tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D OE_3503F uppS1; tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis [PATH:hsl00909]
D OE_2014F fdfT; squalene synthase K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis [PATH:hsl00906]
D OE_3093R crtB1; phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D OE_3376F crtB2; phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D OE_3380R lye; lycopene elongase K20616 lyeJ; lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming) [EC:2.5.1.150]
D OE_3381R crtI1; phytoene dehydrogenase (phytoene desaturase) K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D OE_3468R crtI2; phytoene dehydrogenase (phytoene desaturase) K20611 crtD; 1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase [EC:1.3.99.37]
D OE_3377R probable carotenoid biosynthesis protein K08977 cruF; bisanhydrobacterioruberin hydratase [EC:4.2.1.161]
D OE_3983R crtY; lycopene beta-cyclase K22502 crtY; lycopene beta-cyclase [EC:5.5.1.19]
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation [PATH:hsl00907]
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
D OE_1014R graD5; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1078F aglF1; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1114F graD3; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1578F graD1; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_2530F aglF2; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1016R graD2; sugar nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D OE_2566R menF; isochorismate synthase K02552 menF; menaquinone-specific isochorismate synthase [EC:5.4.4.2]
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:hsl00261]
D OE_4333R lysC; aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D OE_3063F asd; aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:hsl00521]
D OE_4691R glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
D OE_4094F pmm1; phosphohexomutase (phosphoglucomutase / phosphomannomutase) K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D OE_2970R suhB; probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D OE_1014R graD5; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1078F aglF1; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1114F graD3; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1578F graD1; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_2530F aglF2; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1016R graD2; sugar nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
D OE_4691R glcK; glucokinase K25026 glk; glucokinase [EC:2.7.1.2]
C 00525 Acarbose and validamycin biosynthesis
D OE_1014R graD5; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1078F aglF1; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1114F graD3; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1578F graD1; sugar nucleotidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_2530F aglF2; UTP--glucose-1-phosphate uridylyltransferase AglF K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D OE_1016R graD2; sugar nucleotidyltransferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
C 00401 Novobiocin biosynthesis [PATH:hsl00401]
D OE_2770F tyrA; prephenate dehydrogenase K04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_2507R hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis [PATH:hsl00405]
D OE_6093F phzF2; PhzF family protein K06998 phzF; trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC:5.3.3.17]
D OE_1568F pabB; aminodeoxychorismate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D OE_3332R trpE1; anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D OE_3331R trpG1; anthranilate synthase component 2 K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D OE_4021F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_4695F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites [PATH:hsl00999]
D OE_2857F mat; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D OE_1565F aroE; shikimate dehydrogenase K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
D OE_2650F idsA1; bifunctional short chain isoprenyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D OE_4010F idsA2; bifunctional short chain isoprenyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:hsl00362]
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D OE_4500R acd6; glutaryl-CoA dehydrogenase K00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]
D OE_2015R hbd1; 3-hydroxyacyl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation [PATH:hsl00625]
D OE_2133R aldH2; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D OE_4529F aldH1; aldehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
D OE_2623R porA; pyruvate--ferredoxin oxidoreductase alpha subunit K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D OE_2622R porB; pyruvate--ferredoxin oxidoreductase beta subunit K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 00643 Styrene degradation
D OE_5189F 3-oxoacid CoA-transferase K01026 pct; propionate CoA-transferase [EC:2.8.3.1]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation [PATH:hsl00984]
D OE_3884F acaB3; acetyl-CoA C-acyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:hsl03020]
D OE_4741R rpoB1; DNA-directed RNA polymerase subunit B' K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D OE_4742R rpoB2; DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D OE_4740R rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D OE_4739R rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D OE_2631F rpoD; DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D OE_2267F rpoL; DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D OE_3874R rpoE1; DNA-directed RNA polymerase subunit E K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D OE_2678R rpoF; DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D OE_4743R rpoH; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D OE_2638F rpoK; DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D OE_2637F rpoN; DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D OE_1372R rpoP; DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:hsl03022]
D OE_1399R tfbG; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_1478R tfbF; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_2084R tfbB; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_2281R tfbD; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_4056R tfbA; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_6026R tfbC; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_6071R tfbE; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_6140R tfbH; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_4146F tbpE; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7045F tbpA; homolog to TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7186F tbpC1; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7214R tbpD1; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_8017F tbpC2; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_8046R tbpD2; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_2118F tfeA; transcription initiation factor TFE K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D OE_3010F rad25c; DNA repair helicase Rad25 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D OE_2981F rad3a; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_4424R rad3b; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:hsl03010]
D OE_RRNA16S rRNA16S; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D OE_RRNA23S rRNA23S; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D OE_RRNA5S rRNA5S; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D OE_2159R rps1e; 30S ribosomal protein S1e K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D OE_3405F rps4e; 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D OE_4532F rps6e; 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D OE_3357R rps8e; 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D OE_3062F rps17e; 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D OE_3817R rps19e; 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D OE_3869R rps24e; 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D OE_1820R rps27e; 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D OE_3868R rps31e; 30S ribosomal protein S31e K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D OE_2664F rps28e; 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D OE_2641F rps2; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D OE_3395F rps3; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D OE_2628F rps4; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D OE_3415F rps5; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D OE_4735R rps7; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D OE_3410F rps8; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D OE_2635F rps9; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D OE_4720R rps10a; 30S ribosomal protein S10a K02946 RP-S10; small subunit ribosomal protein S10
D OE_2629F rps11; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D OE_4736R rps12; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D OE_2627F rps13; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D OE_3408F rps14; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D OE_2165R rps15; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D OE_3400F rps17; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D OE_3393F rps19; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D OE_3389F rpl4; 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D OE_2662F rpl8e; 50S ribosomal protein L8e K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D OE_1160R rpl16; 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D OE_1294R rpl15e; 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D OE_2632F rpl18e; 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D OE_3413F rpl19e; 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D OE_2679R rpl21e; 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D OE_2665F rpl24e; 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D OE_4459R rpl31e; 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D OE_3412F rpl32e; 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D OE_3141R rpl37e; 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D OE_1373R rpl43e; 50S ribosomal protein L43e K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D OE_4460R rpl39e; 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D OE_3898F rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D OE_1821R rpl42e; 50S ribosomal protein L42e K02929 RP-L44e; large subunit ribosomal protein L44e
D OE_2602R rpl1; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D OE_3392F rpl2; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D OE_3388F rpl3; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D OE_3407F rpl5; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D OE_3411F rpl6; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D OE_2601R rpl10; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D OE_2603R rpl11; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D OE_2600R rpl12; 50S ribosomal protein L12 K02869 RP-L12; large subunit ribosomal protein L12
D OE_2633F rpl13; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D OE_3402F rpl14; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D OE_3417F rpl15; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D OE_3414F rpl18; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D OE_3394F rpl22; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D OE_3390F rpl23; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D OE_3404F rpl24; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D OE_3396F rpl29; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D OE_3416F rpl30; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
C 00970 Aminoacyl-tRNA biosynthesis [PATH:hsl00970]
D OE_tRNAAla1 tRNAAla1; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAAla2 tRNAAla2; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAAla3 tRNAAla3; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAAla4 tRNAAla4; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAArg1 tRNAArg1; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg2 tRNAArg2; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg3 tRNAArg3; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg4 tRNAArg4; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg5 tRNAArg5; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAAsn tRNAAsn; tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D OE_tRNAAsp tRNAAsp; tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D OE_tRNACys tRNACys; tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D OE_tRNAGln1 tRNAGln1; tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D OE_tRNAGln2 tRNAGln2; tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D OE_tRNAGlu1 tRNAGlu1; tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D OE_tRNAGlu2 tRNAGlu2; tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D OE_tRNAGly1 tRNAGly1; tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D OE_tRNAGly2 tRNAGly2; tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D OE_tRNAGly3 tRNAGly3; tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D OE_tRNAHis tRNAHis; tRNA-His K14226 tRNA-His; tRNA His
D OE_tRNAIle tRNAIle; tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D OE_tRNALeu1 tRNALeu1; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu2 tRNALeu2; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu3 tRNALeu3; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu4 tRNALeu4; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu5 tRNALeu5; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALys1 tRNALys1; tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D OE_tRNALys2 tRNALys2; tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D OE_tRNAIniMet1 tRNAIniMet1; tRNA-Met K14230 tRNA-Met; tRNA Met
D OE_tRNAIniMet2 tRNAIniMet2; tRNA-Met K14230 tRNA-Met; tRNA Met
D OE_tRNAMet tRNAMet; tRNA-Met K14230 tRNA-Met; tRNA Met
D OE_tRNAPhe tRNAPhe; tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D OE_tRNAPro1 tRNAPro1; tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D OE_tRNAPro2 tRNAPro2; tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D OE_tRNAPro3 tRNAPro3; tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D OE_tRNASer1 tRNASer1; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNASer2 tRNASer2; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNASer3 tRNASer3; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNASer4 tRNASer4; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNAThr1 tRNAThr1; tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D OE_tRNAThr2 tRNAThr2; tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D OE_tRNAThr3 tRNAThr3; tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D OE_tRNATrp tRNATrp; tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D OE_tRNATyr tRNATyr; tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D OE_tRNAVal1 tRNAVal1; tRNA-Val K14237 tRNA-Val; tRNA Val
D OE_tRNAVal2 tRNAVal2; tRNA-Val K14237 tRNA-Val; tRNA Val
D OE_tRNAVal3 tRNAVal3; tRNA-Val K14237 tRNA-Val; tRNA Val
D OE_2652F gltS; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D OE_2284F gatA; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D OE_1522F gatB; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D OE_2283F gatC; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D OE_3591F gatD; glutamyl-tRNA(Gln) amidotransferase subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D OE_2929R gatE; glutamyl-tRNA(Gln) amidotransferase subunit E K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D OE_4198F alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D OE_1687F aspS; aspartate--tRNA ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D OE_4307F glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D OE_3580R thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D OE_3893F serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D OE_2594F cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D OE_1496R metS; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D OE_4572R valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D OE_4118R leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D OE_4068F ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D OE_3826F lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D OE_5203F argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D OE_1595F proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D OE_3812R hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D OE_4505F pheS; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D OE_4507F pheT; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D OE_4139R tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D OE_4101R trpS1; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D OE_4132R trpS2; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport [PATH:hsl03013]
D OE_3371F homolog to translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4721R tef1a1; translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4467F NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3
C 03015 mRNA surveillance pathway [PATH:hsl03015]
D OE_3973F arf1; peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1
D OE_3152R pelA; mRNA surveillance protein pelota K06965 PELO; protein pelota
C 03008 Ribosome biogenesis in eukaryotes [PATH:hsl03008]
D OE_2685F nop5; rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 K14564 NOP56; nucleolar protein 56
D OE_1817R nop10; tRNA/rRNA pseudouridine synthase complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D OE_3398F rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D OE_2832R rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D OE_2834R rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D OE_4637R probable GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein
D OE_4467F NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3
D OE_4458R tif6; translation initiation factor aIF-6 K03264 EIF6; translation initiation factor 6
D OE_2828R SBDS family protein K14574 SDO1; ribosome maturation protein SDO1
D OE_2506R adk2; probable adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D OE_4133R rio1; RIO-type serine/threonine protein kinase Rio1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D OE_1298R rio2; RIO-type serine/threonine protein kinase Rio2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:hsl03060]
D OE_3418F secY; protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D OE_3784R secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D OE_3787R secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D OE_4450R srp54; signal recognition particle 54K protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D OE_SRPRNA RNA7S; signal recognition particle 7S RNA K01983 ffs; signal recognition particle 4.5S RNA
D OE_4454R ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D OE_1558R secE; protein translocase subunit SecE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D OE_2950R srp19; signal recognition particle 19K protein K03105 SRP19; signal recognition particle subunit SRP19
D OE_1547R arsA2; ArsA family ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D OE_5440F arsA1; ArsA-type transport ATPase (probable substrate arsenite) K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D OE_2186R tatA; Sec-independent protein translocase subunit TatA K03116 tatA; sec-independent protein translocase protein TatA
D OE_4181R tatC2; Sec-independent protein translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D OE_4182F tatC1; Sec-independent protein translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D OE_4388R sec11; signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum [PATH:hsl04141]
D OE_1558R secE; protein translocase subunit SecE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D OE_1008F homolog to oligosaccharyl transferase K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
D OE_3112R cdc48b; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_3356F cdc48a; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_1156F hsp20A; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_3491R hsp20C; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_3541R hsp20F; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_5083R hsp20E; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_1818R tif2a; translation initiation factor aIF-2 alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
D OE_3898F rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D OE_3868R rps31e; 30S ribosomal protein S31e K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 04122 Sulfur relay system [PATH:hsl04122]
D OE_4355R tssA1; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D OE_4356F tssA2; thiosulfate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D OE_1139F moaE; molybdopterin synthase catalytic subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D OE_1142F moaA; probable cyclic pyranopterin monophosphate synthase K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D OE_3595R samp1; ubiquitin-like modifier protein SAMP1 K03636 moaD; sulfur-carrier protein
D OE_2825F moaC; probable cyclic pyranopterin monophosphate synthase accessory protein K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D OE_3565F moaB; molybdopterin adenylyltransferase K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D OE_2858F thiI; ThiI-type thiouridine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D OE_4193R samp2; ubiquitin-like modifier protein SAMP2 K03154 thiS; sulfur carrier protein
D OE_6190R UPF0033 family protein
D OE_7070R UPF0033 family protein
C 03050 Proteasome [PATH:hsl03050]
D OE_1765R pan2; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D OE_3805R pan1; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D OE_1275F psmA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D OE_2296F psmB; proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:hsl03018]
D OE_2640F eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D OE_4718F vacB; homolog to ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D OE_2648F beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D OE_1737R dnaK; Hsp70-type molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:hsl03030]
D OE_3509R dnaG; DNA primase DnaG K02316 dnaG; DNA primase [EC:2.7.7.101]
D OE_1400F rnhA2; ribonuclease H, type 1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D OE_3780F rnhB; ribonuclease H, type 2 K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D OE_1777F polB1; DNA-directed DNA polymerase B K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_6036F polB2; DNA-directed DNA polymerase B2 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_6234F polB3b; probable DNA-directed DNA polymerase B2 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_7114F polB3a; probable DNA-directed DNA polymerase B2 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_4390F polD1; DNA-directed DNA polymerase D exonuclease subunit DP1 K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D OE_4293R polD2; DNA-directed DNA polymerase D large subunit (intein-containing) K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D OE_4052F mcm; ATP-dependent DNA helicase MCM (intein-containing) K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D OE_3108F priS; DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D OE_4163R priL; DNA primase large subunit K18882 priL; DNA primase large subunit
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
D OE_4165R pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D OE_4142F rfcC; replication factor C small subunit K04801 rfcS; replication factor C small subunit
D OE_4195F rfcA; replication factor C small subunit K04801 rfcS; replication factor C small subunit
D OE_3305F rfcB; replication factor C large subunit K04800 rfcL; replication factor C large subunit
D OE_3147F dna2; ATP-dependent DNA helicase Dna2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D OE_2939R fen1; flap endonuclease Fen1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D OE_2298F ligB; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:hsl03410]
D OE_2814F DNA N-glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D OE_1589F nthB; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D OE_1890R nthA; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D OE_3165R mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D OE_4165R pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D OE_2939R fen1; flap endonuclease Fen1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D OE_2298F ligB; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D OE_2870R DNA N-glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D OE_2758R uracil-DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D OE_3906F udg; uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D OE_1304F apn1; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D OE_4282F recJ1; single-stranded-DNA-specific exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
C 03420 Nucleotide excision repair [PATH:hsl03420]
D OE_4699F uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D OE_4353R uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D OE_4344F uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D OE_4677F uvrD; repair helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D OE_3010F rad25c; DNA repair helicase Rad25 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D OE_2981F rad3a; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_4424R rad3b; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
D OE_4165R pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D OE_2298F ligB; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:hsl03430]
D OE_1272R mutS1b; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D OE_1286R mutS1a; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D OE_4183F mutS5a; DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2
D OE_1267R mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D OE_4677F uvrD; repair helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D OE_4282F recJ1; single-stranded-DNA-specific exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D OE_4165R pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
D OE_2298F ligB; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination [PATH:hsl03440]
D OE_4282F recJ1; single-stranded-DNA-specific exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
C 03450 Non-homologous end-joining
D OE_2939R fen1; flap endonuclease Fen1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1 [PATH:hsl03250]
D OE_3693F ppiA; CYPL-type peptidylprolyl isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D OE_3872R spt4; transcription elongation factor Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
D OE_1557R spt5; transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus and Alphavirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03273 Virion - Lassa virus and SFTS virus
C 03272 Virion - Hepatitis viruses
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:hsl02010]
D OE_3270R ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/thiosulfate/molybdate) K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D OE_3269R ABC-type transport system permease protein (probable substrate sulfate/thiosulfate/molybdate) K15496 wtpB; molybdate/tungstate transport system permease protein
D OE_2348R sfuA; ABC-type transport system periplasmic substrate-binding protein (probable substrate iron) K02012 afuA; iron(III) transport system substrate-binding protein
D OE_2346R sfuB; ABC-type transport system permease protein (probable substrate iron) K02011 afuB; iron(III) transport system permease protein
D OE_2343R sfuC; ABC-type transport system ATP-binding protein (probable substrate iron) K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D OE_3641F thiB2; ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) K02064 thiB; thiamine transport system substrate-binding protein
D OE_4357F thiB1; ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) K02064 thiB; thiamine transport system substrate-binding protein
D OE_4358F thiP; ABC-type transport system permease protein (probable substrate thiamine) K02063 thiP; thiamine transport system permease protein
D OE_4359F thiQ; ABC-type transport system ATP-binding protein (probable substrate thiamine) K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D OE_2196F chemotactic signal transduction system periplasmic substrate-binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein
D OE_3629R potD; ABC-type transport system periplasmic substrate-binding protein (probable substrate spermidine/putrescine) K11069 potD; spermidine/putrescine transport system substrate-binding protein
D OE_3625R potC; ABC-type transport system permease protein (probable substrate spermidine/putrescine) K11070 potC; spermidine/putrescine transport system permease protein
D OE_3627R potB; ABC-type transport system permease protein (probable substrate spermidine/putrescine) K11071 potB; spermidine/putrescine transport system permease protein
D OE_3631F potA; ABC-type transport system ATP-binding protein (probable substrate spermidine/putrescine) K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D OE_2170R chemotactic signal transduction system periplasmic substrate-binding protein K07335 bmpA; basic membrane protein A and related proteins
D OE_2317R tsgA; ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) K07335 bmpA; basic membrane protein A and related proteins
D OE_2315R tsgB; ABC-type transport system permease protein (probable substrate sugar) K23535 nupB; general nucleoside transport system permease protein
D OE_2314R tsgC; ABC-type transport system permease protein (probable substrate sugar) K23536 nupC; general nucleoside transport system permease protein
D OE_2316R tsgD; ABC-type transport system ATP-binding protein (probable substrate sugar) K23537 nupA; general nucleoside transport system ATP-binding protein
D OE_5166F ugpB; ABC-type transport system periplasmic substrate-binding protein (probable substrate glycerol-3-phosphate) K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
D OE_5168F ugpA; ABC-type transport system permease protein (probable substrate glycerol-3-phosphate) K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein
D OE_5169F ugpE; ABC-type transport system permease protein (probable substrate glycerol-3-phosphate) K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein
D OE_5170F ugpC; ABC-type transport system ATP-binding protein (probable substrate glycerol-3-phosphate) K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10]
D OE_1679R pstS2; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) K02040 pstS; phosphate transport system substrate-binding protein
D OE_4485R pstS1; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) K02040 pstS; phosphate transport system substrate-binding protein
D OE_1678R pstC2; ABC-type transport system permease protein (probable substrate phosphate) K02037 pstC; phosphate transport system permease protein
D OE_4483R pstC1; ABC-type transport system permease protein (probable substrate phosphate) K02037 pstC; phosphate transport system permease protein
D OE_1676R pstA2; ABC-type transport system permease protein (probable substrate phosphate) K02038 pstA; phosphate transport system permease protein
D OE_4480R pstA1; ABC-type transport system permease protein (probable substrate phosphate) K02038 pstA; phosphate transport system permease protein
D OE_1675R pstB2; ABC-type transport system ATP-binding protein (probable substrate phosphate) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D OE_4479R pstB1; ABC-type transport system ATP-binding protein (probable substrate phosphate) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D OE_3910R phnD; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate/phosphonate) K02044 phnD; phosphonate transport system substrate-binding protein
D OE_3907R phnE; ABC-type transport system permease protein (probable substrate phosphate/phosphonate) K02042 phnE; phosphonate transport system permease protein
D OE_3908R phnC; ABC-type transport system ATP-binding protein (probable substrate phosphate/phosphonate) K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D OE_5147R znuA; ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) K09815 znuA; zinc transport system substrate-binding protein
D OE_5144R znuB; ABC-type transport system permease protein (probable substrate zinc) K09816 znuB; zinc transport system permease protein
D OE_5146R znuC; ABC-type transport system ATP-binding protein (probable substrate zinc) K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D OE_3318R cbiN; ABC-type transport system protein CbiN (probable substrate cobalt) K02009 cbiN; cobalt/nickel transport protein
D OE_3319R cbiM; ABC-type transport system permease protein (probable substrate cobalt) K02007 cbiM; cobalt/nickel transport system permease protein
D OE_3317R cbiQ; ABC-type transport system permease protein (probable substrate cobalt) K02008 cbiQ; cobalt/nickel transport system permease protein
D OE_3315R cbiO; ABC-type transport system ATP-binding protein (probable substrate cobalt) K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D OE_4255F bioY; biotin transport protein BioY K03523 bioY; biotin transport system substrate-specific component
D OE_4257C1F bioN; ABC-type transport system permease protein (probable substrate biotin) K16783 bioN; biotin transport system permease protein
D OE_4256F bioM; ABC-type transport system ATP-binding protein (probable substrate biotin) K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:hsl03070]
D OE_3784R secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D OE_3787R secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D OE_3418F secY; protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D OE_4454R ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D OE_4450R srp54; signal recognition particle 54K protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D OE_2186R tatA; Sec-independent protein translocase subunit TatA K03116 tatA; sec-independent protein translocase protein TatA
D OE_4181R tatC2; Sec-independent protein translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D OE_4182F tatC1; Sec-independent protein translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:hsl02020]
D OE_5192R aph; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D OE_1679R pstS2; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) K02040 pstS; phosphate transport system substrate-binding protein
D OE_4485R pstS1; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) K02040 pstS; phosphate transport system substrate-binding protein
D OE_5052F kdpA; potassium-transporting ATPase subunit A K01546 kdpA; potassium-transporting ATPase potassium-binding subunit
D OE_5053F kdpB; potassium-transporting ATPase subunit B K01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]
D OE_5054F kdpC; potassium-transporting ATPase subunit C K01548 kdpC; potassium-transporting ATPase KdpC subunit
D OE_5051A1F kdpF; potassium-transporting ATPase subunit F K01545 kdpF; potassium-transporting ATPase KdpF subunit
D OE_3306R ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D OE_1942F citE; homolog to citrate lyase beta subunit K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D OE_1265F major facilitator superfamily transport protein K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
D OE_3922R glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2406R cheR; protein-glutamate O-methyltransferase CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D OE_1536R mpcT; transducer protein MpcT K03406 mcp; methyl-accepting chemotaxis protein
D OE_1929R htr16; transducer protein Htr16 K03406 mcp; methyl-accepting chemotaxis protein
D OE_2168R htrVI; transducer protein HtrVI K03406 mcp; methyl-accepting chemotaxis protein
D OE_2195F htr18; transducer protein Htr18 K03406 mcp; methyl-accepting chemotaxis protein
D OE_2392R htr15; transducer protein Htr15 K03406 mcp; methyl-accepting chemotaxis protein
D OE_3167F htrVIII; transducer protein HtrVIII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3347F htrI; transducer protein HtrI K03406 mcp; methyl-accepting chemotaxis protein
D OE_3473F htrVII; transducer protein HtrVII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3474R cosT; transducer protein CosT K03406 mcp; methyl-accepting chemotaxis protein
D OE_3481R htrII; transducer protein HtrII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3611R basT; transducer protein BasT K03406 mcp; methyl-accepting chemotaxis protein
D OE_2374R cheW2; purine-binding taxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D OE_2419R cheW1; purine-binding taxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D OE_2415R cheA; taxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D OE_2417R cheY; response regulator CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D OE_2416R cheB; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D OE_6185F cydA2; cytochrome bd ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D OE_7065F cydA1; cytochrome bd ubiquinol oxidase subunit I K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D OE_6186F cydB2; cytochrome bd ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D OE_7066F cydB1; cytochrome bd ubiquinol oxidase subunit II K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D OE_1361F degP; probable periplasmic serine protease
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04082 Neuroactive ligand signaling
C 04081 Hormone signaling
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
D OE_1558R secE; protein translocase subunit SecE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C 04142 Lysosome
C 04146 Peroxisome [PATH:hsl04146]
D OE_2912F acs3; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_3891R acs5; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_2645F mvk; mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D OE_3634F icd; isocitrate dehydrogenase (NADP) K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D OE_2708R sod1; superoxide dismutase (Mn) K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
D OE_2906R sod2; superoxide dismutase (Mn) K04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:hsl02024]
D OE_1568F pabB; aminodeoxychorismate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D OE_3332R trpE1; anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D OE_3331R trpG1; anthranilate synthase component 2 K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D OE_6093F phzF2; PhzF family protein K06998 phzF; trans-2,3-dihydro-3-hydroxyanthranilate isomerase [EC:5.3.3.17]
D OE_5273R ABC-type transport system periplasmic substrate-binding protein K02055 ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein
D OE_5270R ABC-type transport system permease protein K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D OE_5272R ABC-type transport system permease protein K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D OE_5268R ABC-type transport system ATP-binding protein K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D OE_2913R beta-lactamase domain protein K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81]
D OE_2912F acs3; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_3891R acs5; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_4305R dppA1; ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D OE_4311F dppA3; ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D OE_4551F dppA2; ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D OE_4304R dppB1; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D OE_4313F dppB3; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D OE_4552F dppB2; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D OE_4303R dppC1; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D OE_4316F dppC3; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D OE_4555F dppC2; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D OE_4302R dppD1; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D OE_4317F dppD3; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D OE_4550F dppDF2; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D OE_4301R dppF1; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02032 ddpF; peptide/nickel transport system ATP-binding protein
D OE_4318F dppF3; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02032 ddpF; peptide/nickel transport system ATP-binding protein
D OE_4612F hly; serine protease halolysin K14645 K14645; serine protease [EC:3.4.21.-]
D OE_3418F secY; protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D OE_4454R ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D OE_4450R srp54; signal recognition particle 54K protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis [PATH:hsl02030]
D OE_1536R mpcT; transducer protein MpcT K03406 mcp; methyl-accepting chemotaxis protein
D OE_1929R htr16; transducer protein Htr16 K03406 mcp; methyl-accepting chemotaxis protein
D OE_2168R htrVI; transducer protein HtrVI K03406 mcp; methyl-accepting chemotaxis protein
D OE_2195F htr18; transducer protein Htr18 K03406 mcp; methyl-accepting chemotaxis protein
D OE_2392R htr15; transducer protein Htr15 K03406 mcp; methyl-accepting chemotaxis protein
D OE_3167F htrVIII; transducer protein HtrVIII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3347F htrI; transducer protein HtrI K03406 mcp; methyl-accepting chemotaxis protein
D OE_3473F htrVII; transducer protein HtrVII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3474R cosT; transducer protein CosT K03406 mcp; methyl-accepting chemotaxis protein
D OE_3481R htrII; transducer protein HtrII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3611R basT; transducer protein BasT K03406 mcp; methyl-accepting chemotaxis protein
D OE_2415R cheA; taxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D OE_2374R cheW2; purine-binding taxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D OE_2419R cheW1; purine-binding taxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D OE_2417R cheY; response regulator CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D OE_2410R cheC3; taxis cluster protein CheC K03410 cheC; chemotaxis protein CheC
D OE_2414R cheC1; taxis cluster protein CheC K03410 cheC; chemotaxis protein CheC
D OE_3280R cheC2; taxis cluster protein CheC K03410 cheC; chemotaxis protein CheC
D OE_2416R cheB; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D OE_2408R cheD; taxis cluster protein CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D OE_2406R cheR; protein-glutamate O-methyltransferase CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D OE_2640F eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04981 Folate transport and metabolism [PATH:hsl04981]
D OE_3566F probable COG0212-type thiamine metabolism protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
D OE_3036F glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 04980 Cobalamin transport and metabolism [PATH:hsl04980]
D OE_3203R pduO; ATP:cob(I)alamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D OE_2006F ygfD; YgfD family GTPase K07588 MMAA; GTPase [EC:3.6.5.-]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
C 04382 Cornified envelope formation
D OE_2739F hutH; histidine ammonia-lyase K01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:hsl01503]
D OE_3693F ppiA; CYPL-type peptidylprolyl isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D OE_1361F degP; probable periplasmic serine protease
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:hsl01000]
C 01001 Protein kinases [BR:hsl01001]
D OE_3866R kae1; KEOPS complex subunit Kae1/Bud32 K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D OE_4133R rio1; RIO-type serine/threonine protein kinase Rio1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D OE_1298R rio2; RIO-type serine/threonine protein kinase Rio2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D OE_2415R cheA; taxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:hsl01009]
D OE_2809R tif2b; translation initiation factor aIF-2 beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2
D OE_4159F ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D OE_4405R serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:hsl01002]
D OE_2946R DUF1119 family protein K28485 psh1; intramembrane aspartyl peptidase
D OE_4201R pibD; prepilin/preflagellin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D OE_1363F guaAa1; GMP synthase (glutamine-hydrolyzing) subunit A K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D OE_3571R guaAb; GMP synthase (glutamine-hydrolyzing) subunit B K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D OE_4502R guaAa2; glutamine amidotransferase (homolog to GMP synthase subunit A) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D OE_3139R purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D OE_1013R glmS; glutamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D OE_2278F asnB; asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D OE_4745R artA; archaeosortase A K24447 artA; archaeosortase A [EC:3.4.22.-]
D OE_1534F Abi/CAAX family protein K07052 K07052; CAAX protease family protein
D OE_3794F Abi/CAAX family protein K07052 K07052; CAAX protease family protein
D OE_3807R pepF; oligoendopeptidase PepF K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
D OE_1656F M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) K12940 abgA; aminobenzoyl-glutamate utilization protein A
D OE_3623R map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D OE_2763F peptidase M24 family protein (homolog to Xaa-Pro dipeptidase) K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D OE_1309F pepB1; aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-]
D OE_4438F pepB2; aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-]
D OE_4571R pepB3; aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) K19689 ampS; aminopeptidase [EC:3.4.11.-]
D OE_4673F cxp; metal-dependent carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D OE_1211F htpX; HtpX-like protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D OE_4663F amzA; archaemetzincin K06974 amzA; archaemetzincin [EC:3.4.-.-]
D OE_3561F metalloprotease JAMM1, desampylating K20110 JAMM1; desampylase [EC:3.4.19.15]
D OE_4685R PrsW family protein K24131 prsW; protease PrsW [EC:3.4.-.-]
D OE_4612F hly; serine protease halolysin K14645 K14645; serine protease [EC:3.4.21.-]
D OE_1465F lon; ATP-dependent protease Lon K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
D OE_4388R sec11; signal peptidase I K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D OE_1934R sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
D OE_2260R rhomboid family protein K28366 rho1; rhomboid family protease [EC:3.4.21.105]
D OE_1541F rhomboid family protein K07059 rho2; rhomboid family protease [EC:3.4.21.105]
D OE_1275F psmA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D OE_2296F psmB; proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D OE_3633R ansA; asparaginase family protein K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
C 01003 Glycosyltransferases [BR:hsl01003]
D OE_2528R aglJ; dolichyl-phosphate hexosyltransferase AglJ K23684 aglJ; dolichol-phosphate hexosyltransferase [EC:2.4.1.-]
D OE_2547R aglG; glycosyltransferase AglG K22844 aglG; glucosyl-dolichyl phosphate glucuronosyltransferase [EC:2.4.1.356]
D OE_2537F gtl8; probable glycosyltransferase, type 2 K23685 aglI; glycosyltransferase AglI [EC:2.4.1.-]
D OE_2546F aglI; glycosyltransferase AglI K23685 aglI; glycosyltransferase AglI [EC:2.4.1.-]
D OE_1482R aglD; glycosyltransferase AglD K23683 aglD; glycosyltransferase AglD [EC:2.4.1.-]
D OE_1008F homolog to oligosaccharyl transferase K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
D OE_2548F aglB; dolichyl-monophosphooligosaccharide--protein glycotransferase AglB K21306 aglB; dolichyl-phosphooligosaccharide-protein glycotransferase [EC:2.4.99.21]
D OE_1906R gth2; probable glycosyltransferase, type 1 K13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]
D OE_1422F gtl5; probable glycosyltransferase, type 2 K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:hsl01011]
D OE_4745R artA; archaeosortase A K24447 artA; archaeosortase A [EC:3.4.22.-]
C 01004 Lipid biosynthesis proteins [BR:hsl01004]
D OE_4021F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_4695F probable oxidoreductase (short-chain dehydrogenase family) K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D OE_1726F acs1; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2450F acs2; acyl-CoA synthetase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D OE_2372F acdA; acetate--CoA ligase (ADP-forming) K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D OE_2912F acs3; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_3891R acs5; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:hsl01006]
D OE_2650F idsA1; bifunctional short chain isoprenyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D OE_4010F idsA2; bifunctional short chain isoprenyl diphosphate synthase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D OE_3505R uppS2; tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D OE_2014F fdfT; squalene synthase K00801 FDFT1; farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
D OE_3093R crtB1; phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D OE_3376F crtB2; phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D OE_2559R menA; 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 menA; 1,4-dihydroxy-2-naphthoate polyprenyltransferase [EC:2.5.1.74]
D OE_1989F ctaB; protoheme IX geranylgeranyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:hsl01007]
D OE_3826F lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D OE_2652F gltS; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D OE_4139R tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D OE_4101R trpS1; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D OE_4132R trpS2; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D OE_2594F cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D OE_5203F argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D OE_1496R metS; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D OE_4068F ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D OE_4572R valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D OE_4118R leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D OE_1687F aspS; aspartate--tRNA ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D OE_3812R hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D OE_4307F glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D OE_3893F serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D OE_1595F proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D OE_3580R thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D OE_4198F alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D OE_4505F pheS; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D OE_4507F pheT; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D OE_1755F aspC1; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_1944R aspC2; pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D OE_2507R hisC; histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D OE_3168R pyridoxal phosphate-dependent aminotransferase K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D OE_5094F dat; diaminobutyrate--2-oxoglutarate aminotransferase K00836 ectB; diaminobutyrate-2-oxoglutarate transaminase [EC:2.6.1.76]
D OE_4268F hemL; glutamate-1-semialdehyde 2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D OE_1574F pabC; aminodeoxychorismate lyase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D OE_3959R ilvE2; branched-chain amino acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:hsl03000]
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
D OE_4146F tbpE; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7045F tbpA; homolog to TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7186F tbpC1; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7214R tbpD1; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_8017F tbpC2; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_8046R tbpD2; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_2621R lrpA1; Lrp/AsnC family transcription regulator LrpA1 K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D OE_2969R Lrp/AsnC family transcription regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D OE_5209R arcR; IclR family transcription regulator ArcR K21827 arcR; IclR family transcriptional regulator, arginine deiminase pathway regulator
D OE_5437R arsR; ArsR family transcription regulator ArsR K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D OE_3589F ArsR family transcription regulator K07721 K07721; ArsR family transcriptional regulator
D OE_1385F thiN; HTH domain protein / thiamine-phosphate synthase K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D OE_5123R gvpE2; PadR family transcription activator GvpE K23305 gvpE; PadR family transcriptional regulator, activator of gas vesicle formation
D OE_7032R gvpE1; PadR family transcription activator GvpE K23305 gvpE; PadR family transcriptional regulator, activator of gas vesicle formation
D OE_1787F SirR/DtxR family transcription regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D OE_1797R sirR; SirR/DtxR family transcription regulator SirR K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D OE_2231R SirR/DtxR family transcription regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D OE_4619R SirR/DtxR family transcription regulator K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D OE_3186F birA1; HTH domain protein / biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D OE_3081F trmB; TrmB family transcription regulator TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D OE_3650R TrmB family transcription regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D OE_3678R TrmB family transcription regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D OE_1268F boa1; sensor/bat box HTH-10 family transcription regulator K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D OE_2448F boa4; integrase family protein / bat box HTH-10 family transcription regulator K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D OE_3101R bat; bacterioopsin activator Bat K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
D OE_2220F HTH-10 family transcription regulator K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
D OE_3273F tfx; Tfx-type DNA-binding protein K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator
D OE_1672F pyrE1; homolog to orotate phosphoribosyltransferase K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
D OE_3946F cro/C1 family transcription regulator K07728 K07728; putative transcriptional regulator
D OE_1707R cro/C1 family transcription regulator K07729 K07729; putative transcriptional regulator
D OE_7009F cro/C1 family transcription regulator K07729 K07729; putative transcriptional regulator
D OE_3206R arNOG05395 family transcription regulator K07730 K07730; putative transcriptional regulator
D OE_3299R cro/C1 family transcription regulator K07731 K07731; putative transcriptional regulator
D OE_1241R NikR family transcription regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D OE_3104F brz; transcription regulator Brz (CPxCG-related small zinc finger protein) K23306 brz; bacteriorhodopsin-regulating zinc finger protein
C 03021 Transcription machinery [BR:hsl03021]
D OE_1399R tfbG; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_1478R tfbF; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_2084R tfbB; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_2281R tfbD; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_4056R tfbA; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_6026R tfbC; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_6071R tfbE; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_6140R tfbH; transcription initiation factor TFB K03124 TFIIB; transcription initiation factor TFIIB
D OE_4146F tbpE; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7045F tbpA; homolog to TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7186F tbpC1; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_7214R tbpD1; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_8017F tbpC2; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_8046R tbpD2; TATA-binding transcription initiation factor K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D OE_2118F tfeA; transcription initiation factor TFE K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D OE_3010F rad25c; DNA repair helicase Rad25 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D OE_2981F rad3a; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_4424R rad3b; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_3872R spt4; transcription elongation factor Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
D OE_1557R spt5; transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D OE_4738R nusA; transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D OE_4740R rpoA1; DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D OE_4739R rpoA2; DNA-directed RNA polymerase subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D OE_4741R rpoB1; DNA-directed RNA polymerase subunit B' K03044 rpoB1; DNA-directed RNA polymerase subunit B' [EC:2.7.7.6]
D OE_4742R rpoB2; DNA-directed RNA polymerase subunit B'' K03045 rpoB2; DNA-directed RNA polymerase subunit B" [EC:2.7.7.6]
D OE_2631F rpoD; DNA-directed RNA polymerase subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D OE_3874R rpoE1; DNA-directed RNA polymerase subunit E K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D OE_2678R rpoF; DNA-directed RNA polymerase subunit F K03051 rpoF; DNA-directed RNA polymerase subunit F [EC:2.7.7.6]
D OE_4743R rpoH; DNA-directed RNA polymerase subunit H K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D OE_2638F rpoK; DNA-directed RNA polymerase subunit K K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D OE_2267F rpoL; DNA-directed RNA polymerase subunit L K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D OE_2637F rpoN; DNA-directed RNA polymerase subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D OE_1372R rpoP; DNA-directed RNA polymerase subunit P K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D OE_1637R tfs1; transcription elongation factor TFS K03057 tfs; transcription factor S
D OE_3452F tfs2; transcription elongation factor TFS K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:hsl03019]
D OE_3872R spt4; transcription elongation factor Spt4 K15171 SUPT4H1; transcription elongation factor SPT4
D OE_1557R spt5; transcription elongation factor Spt5 K15172 SUPT5H; transcription elongation factor SPT5
D OE_3112R cdc48b; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_3356F cdc48a; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_3152R pelA; mRNA surveillance protein pelota K06965 PELO; protein pelota
D OE_3973F arf1; peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1
D OE_3371F homolog to translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4721R tef1a1; translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_2648F beta-lactamase domain protein K12574 rnj; ribonuclease J [EC:3.1.-.-]
D OE_4718F vacB; homolog to ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D OE_2640F eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D OE_1737R dnaK; Hsp70-type molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D OE_4041F ashA; archaea-specific helicase AshA K03725 K03725; putative ATP-dependent RNA helicase [EC:5.6.2.-]
C 03041 Spliceosome
C 03011 Ribosome [BR:hsl03011]
D OE_2159R rps1e; 30S ribosomal protein S1e K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D OE_3405F rps4e; 30S ribosomal protein S4e K02987 RP-S4e; small subunit ribosomal protein S4e
D OE_4532F rps6e; 30S ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D OE_3357R rps8e; 30S ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D OE_3062F rps17e; 30S ribosomal protein S17e K02962 RP-S17e; small subunit ribosomal protein S17e
D OE_3817R rps19e; 30S ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D OE_3869R rps24e; 30S ribosomal protein S24e K02974 RP-S24e; small subunit ribosomal protein S24e
D OE_1820R rps27e; 30S ribosomal protein S27e K02978 RP-S27e; small subunit ribosomal protein S27e
D OE_3868R rps31e; 30S ribosomal protein S31e K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D OE_2664F rps28e; 30S ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D OE_3389F rpl4; 50S ribosomal protein L4 K02930 RP-L4e; large subunit ribosomal protein L4e
D OE_2662F rpl8e; 50S ribosomal protein L8e K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D OE_1160R rpl16; 50S ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D OE_1294R rpl15e; 50S ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D OE_2632F rpl18e; 50S ribosomal protein L18e K02883 RP-L18e; large subunit ribosomal protein L18e
D OE_3413F rpl19e; 50S ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D OE_2679R rpl21e; 50S ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D OE_2665F rpl24e; 50S ribosomal protein L24e K02896 RP-L24e; large subunit ribosomal protein L24e
D OE_4459R rpl31e; 50S ribosomal protein L31e K02910 RP-L31e; large subunit ribosomal protein L31e
D OE_3412F rpl32e; 50S ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D OE_3141R rpl37e; 50S ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D OE_1373R rpl43e; 50S ribosomal protein L43e K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D OE_4460R rpl39e; 50S ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D OE_3898F rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D OE_1821R rpl42e; 50S ribosomal protein L42e K02929 RP-L44e; large subunit ribosomal protein L44e
D OE_2641F rps2; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D OE_3395F rps3; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D OE_2628F rps4; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D OE_3415F rps5; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D OE_4735R rps7; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D OE_3410F rps8; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D OE_2635F rps9; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D OE_4720R rps10a; 30S ribosomal protein S10a K02946 RP-S10; small subunit ribosomal protein S10
D OE_2629F rps11; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D OE_4736R rps12; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D OE_2627F rps13; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D OE_3408F rps14; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D OE_2165R rps15; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D OE_3400F rps17; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D OE_3393F rps19; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D OE_2602R rpl1; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D OE_3392F rpl2; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D OE_3388F rpl3; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D OE_3407F rpl5; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D OE_3411F rpl6; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D OE_2601R rpl10; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D OE_2603R rpl11; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D OE_2633F rpl13; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D OE_3402F rpl14; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D OE_3417F rpl15; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D OE_3414F rpl18; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D OE_3394F rpl22; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D OE_3390F rpl23; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D OE_3404F rpl24; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D OE_3396F rpl29; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D OE_3416F rpl30; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D OE_2600R rpl12; 50S ribosomal protein L12 K02869 RP-L12; large subunit ribosomal protein L12
D OE_RRNA16S rRNA16S; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D OE_RRNA23S rRNA23S; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D OE_RRNA5S rRNA5S; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 03009 Ribosome biogenesis [BR:hsl03009]
D OE_2685F nop5; rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 K14564 NOP56; nucleolar protein 56
D OE_1817R nop10; tRNA/rRNA pseudouridine synthase complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D OE_4124R KH domain protein K06961 KRR1; ribosomal RNA assembly protein
D OE_4133R rio1; RIO-type serine/threonine protein kinase Rio1 K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D OE_1298R rio2; RIO-type serine/threonine protein kinase Rio2 K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D OE_2506R adk2; probable adenylate kinase K18532 AK6; adenylate kinase [EC:2.7.4.3]
D OE_3895F UPF0293 family protein K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D OE_4667R ABC-type transport system ATP-binding protein K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D OE_4637R probable GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein
D OE_3398F rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D OE_2832R rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D OE_2834R rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D OE_4458R tif6; translation initiation factor aIF-6 K03264 EIF6; translation initiation factor 6
D OE_4467F NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3
D OE_2828R SBDS family protein K14574 SDO1; ribosome maturation protein SDO1
D OE_3112R cdc48b; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_3356F cdc48a; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_4377R oapA; origin-associated GTP-binding protein OapA K03595 era; GTPase
D OE_2689F fib; fibrillarin-like rRNA/tRNA 2'-O-methyltransferase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D OE_2662F rpl8e; 50S ribosomal protein L8e K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D OE_2948R gar1; tRNA/rRNA pseudouridine synthase complex protein Gar1 K07569 gar1; RNA-binding protein
D OE_4738R nusA; transcription elongation factor NusA K02600 nusA; transcription termination/antitermination protein NusA
D OE_2674R ksgA; ribosome biogenesis protein KsgA, 16S rRNA-methylating K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D OE_4177F rlmE; 23S rRNA (uridine-2'-O-) methyltransferase K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D OE_4615F GNAT family acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D OE_1158R rimK; RimK family protein K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D OE_3022R DUF181 family protein K09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor
D OE_4688F aubA; RNA-binding protein AU-1 K22469 fau-1; ribonuclease FAU-1 [EC:3.1.26.-]
D OE_2827R hflX2; GTP-binding protein HflX K03665 hflX; GTPase
D OE_4665R hflX1; GTP-binding protein HflX K03665 hflX; GTPase
D OE_4244F yrdC; threonylcarbamoyl-AMP synthase YrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D OE_1909F CRM domain protein K07574 yhbY; RNA-binding protein
D OE_1757R GTP-binding protein K06942 ychF; ribosome-binding ATPase
D OE_3460F GTP-binding protein K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:hsl03016]
D OE_3398F rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D OE_2832R rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D OE_2834R rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D OE_1907F rnp4; ribonuclease P protein component 4 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D OE_4141R rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D OE_3085R rtcB; tRNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D OE_3090R homolog to archaease K24956 ZBTB8OS; protein archease
D OE_3371F homolog to translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4721R tef1a1; translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_2652F gltS; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D OE_1595F proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D OE_4068F ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D OE_4118R leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D OE_1496R metS; methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D OE_5203F argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D OE_4198F alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D OE_4307F glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D OE_3580R thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D OE_3893F serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D OE_2594F cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D OE_4572R valS; valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D OE_3812R hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D OE_4505F pheS; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D OE_4507F pheT; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D OE_4139R tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D OE_4101R trpS1; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D OE_4132R trpS2; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D OE_1560R dtdA; D-aminoacyl-tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D OE_4065R hit1; histidine triad family protein (homolog to bis(5'-nucleosyl)-tetraphosphatase) K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D OE_3617F MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D OE_3917F trm1; tRNA (guanine(26)-N(2))-dimethyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D OE_2614F trm5; tRNA (guanine(37)-N(1))-methyltransferase K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D OE_1636F trmI; tRNA (adenine-N(1))-methyltransferase TrmI K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D OE_2210R probable S-adenosylmethionine-dependent methyltransferase K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D OE_3967R taw1; tRNA-(4-demethylwyosine) synthase K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D OE_4468F taw2; tRNA-(4-demethylwyosine) alpha-amino-alpha-carboxypropyltransferase K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D OE_3810R truA; tRNA pseudouridine synthase TruA K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D OE_3430F cbf5; tRNA/rRNA pseudouridine synthase Cbf5 K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D OE_1378R truD; tRNA pseudouridine(13) synthase TruD K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D OE_3778F pus10; tRNA pseudouridine synthase Pus10 K07583 PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]
D OE_3154R elp3; homolog to elongator complex protein ELP3 K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D OE_4244F yrdC; threonylcarbamoyl-AMP synthase YrdC K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D OE_RNASEP RNAseP; RNase P RNA K01978 rnpB; RNase P catalytic RNA component
D OE_1222R cca; tRNA adenylyltransferase, CCA-adding K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D OE_4102R endA; tRNA-splicing endonuclease K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D OE_3826F lysS; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D OE_1687F aspS; aspartate--tRNA ligase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D OE_2923F tRNA (cytidine/uridine-2'-O-)-methyltransferase K15396 trmJ; tRNA (cytidine32/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]
D OE_3775R trmY; tRNA (pseudouridine(54)-N(1))-methyltransferase K16317 trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]
D OE_4144R trmG10; tRNA (guanine(10),N(2))-dimethyltransferase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D OE_2117F trm56; tRNA (cytidine(56)-2'-O)-methyltransferase K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D OE_1748R cna; tRNA/rRNA cytosine-C5-methylase K22446 K22446; tRNA (cytosine49-C5)-methyltransferase [EC:2.1.1.-]
D OE_3866R kae1; KEOPS complex subunit Kae1/Bud32 K15904 kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]
D OE_4326F cgi121; KEOPS complex subunit Cgi121 K09119 cgi121; KEOPS complex subunit Cgi121
D OE_1371B1R pcc1; KEOPS complex subunit Pcc1 K09741 pcc1; KEOPS complex subunit Pcc1
D OE_5195R queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D OE_2495F PtpS family protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D OE_5198R queD; 6-carboxy-5,6,7,8-tetrahydropterin synthase K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D OE_5197R queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D OE_3749R tgtA; tRNA-guanine(15) transglycosylase K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D OE_2858F thiI; ThiI-type thiouridine biosynthesis protein K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D OE_3943R tiaS; tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D OE_2656R tmcA; tRNA(Met) cytidine acetyltransferase TmcA K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D OE_4718F vacB; homolog to ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
C 03012 Translation factors [BR:hsl03012]
D OE_3470F tif1A2; translation initiation factor aIF-1A K03236 EIF1A; translation initiation factor 1A
D OE_4136R tif1A1; translation initiation factor aIF-1A K03236 EIF1A; translation initiation factor 1A
D OE_4626R tif1; translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3) K03113 EIF1; translation initiation factor 1
D OE_1818R tif2a; translation initiation factor aIF-2 alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
D OE_2809R tif2b; translation initiation factor aIF-2 beta subunit K03238 EIF2S2; translation initiation factor 2 subunit 2
D OE_3876R tif2c; translation initiation factor aIF-2 gamma subunit K03242 EIF2S3; translation initiation factor 2 subunit 3
D OE_3082R tif2Bd; translation initiation factor aIF-2B delta subunit K03680 EIF2B4; translation initiation factor eIF-2B subunit delta
D OE_3487R tif5A; translation initiation factor aIF-5A K03263 EIF5A; translation initiation factor 5A
D OE_3800F tif5B; translation initiation factor aIF-5B (bacterial-type IF2) K03243 EIF5B; translation initiation factor 5B
D OE_4458R tif6; translation initiation factor aIF-6 K03264 EIF6; translation initiation factor 6
D OE_3371F homolog to translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4721R tef1a1; translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_2683R tef1b; translation elongation factor aEF-1 beta subunit K03232 EEF1B; elongation factor 1-beta
D OE_4729R tef2; translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D OE_2257F dph2; S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D OE_1579R dph6; diphthamide biosynthesis protein Dph6 K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D OE_3973F arf1; peptide chain release factor aRF-1 K03265 ETF1; peptide chain release factor subunit 1
D OE_2671R prmC; protein N5-glutamine methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D OE_1379R pth; peptidyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:hsl03110]
D OE_1737R dnaK; Hsp70-type molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D OE_3925R ths2; thermosome subunit 2 K22447 cct; archaeal chaperonin
D OE_4122R ths1; thermosome subunit 1 K22447 cct; archaeal chaperonin
D OE_1736R dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D OE_1742R grpE; DnaJ/DnaK ATPase stimulator GrpE K03687 GRPE; molecular chaperone GrpE
D OE_1156F hsp20A; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_3491R hsp20C; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_3541R hsp20F; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_5083R hsp20E; Hsp20-type molecular chaperone K13993 HSP20; HSP20 family protein
D OE_4456R pfdA; prefoldin alpha subunit K04797 pfdA; prefoldin alpha subunit
D OE_1371R pfdB; prefoldin beta subunit K04798 pfdB; prefoldin beta subunit
D OE_2229F dmsD; Tat proofreading chaperone DmsD K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D OE_4612F hly; serine protease halolysin K14645 K14645; serine protease [EC:3.4.21.-]
D OE_3693F ppiA; CYPL-type peptidylprolyl isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D OE_2853R mtfK; FKBP-type peptidylprolyl isomerase K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D OE_1277F trxA3; thioredoxin K03671 TXN; thioredoxin
D OE_4648F trxA2; thioredoxin K03671 TXN; thioredoxin
D OE_6204F trxA1b; thioredoxin K03671 TXN; thioredoxin
D OE_7084F trxA1a; thioredoxin K03671 TXN; thioredoxin
D OE_1673F grx4; glutaredoxin K07390 grxD; monothiol glutaredoxin
C 04131 Membrane trafficking [BR:hsl04131]
D OE_2667F ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D OE_3112R cdc48b; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_3356F cdc48a; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_1794R uncharacterized protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D OE_1547R arsA2; ArsA family ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D OE_5440F arsA1; ArsA-type transport ATPase (probable substrate arsenite) K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D OE_1558R secE; protein translocase subunit SecE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D OE_1818R tif2a; translation initiation factor aIF-2 alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
D OE_1495R pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D OE_3371F homolog to translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4721R tef1a1; translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:hsl04121]
D OE_3898F rpl40e; 50S ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D OE_3868R rps31e; 30S ribosomal protein S31e K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
C 03051 Proteasome [BR:hsl03051]
D OE_1275F psmA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D OE_2296F psmB; proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D OE_1765R pan2; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
D OE_3805R pan1; proteasome-activating nucleotidase K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:hsl03032]
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
D OE_1400F rnhA2; ribonuclease H, type 1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D OE_4165R pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D OE_3147F dna2; ATP-dependent DNA helicase Dna2 K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D OE_2939R fen1; flap endonuclease Fen1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D OE_2298F ligB; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D OE_1817R nop10; tRNA/rRNA pseudouridine synthase complex protein Nop10 K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D OE_3509R dnaG; DNA primase DnaG K02316 dnaG; DNA primase [EC:2.7.7.101]
D OE_1076F orc9; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_2753F orc8; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_4184F orc6; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_4380F orc7; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_5162R orc5; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_6037R orc4; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_6235F orc10b; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_6288R orc12; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_7115F orc10a; Orc1-type DNA replication protein K10725 cdc6A; archaeal cell division control protein 6
D OE_4052F mcm; ATP-dependent DNA helicase MCM (intein-containing) K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D OE_3108F priS; DNA primase small subunit K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D OE_4163R priL; DNA primase large subunit K18882 priL; DNA primase large subunit
D OE_3109F ginS; DNA replication factor GINS K09723 ginS; DNA replication factor GINS
D OE_3780F rnhB; ribonuclease H, type 2 K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D OE_1777F polB1; DNA-directed DNA polymerase B K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_6036F polB2; DNA-directed DNA polymerase B2 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_6234F polB3b; probable DNA-directed DNA polymerase B2 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_7114F polB3a; probable DNA-directed DNA polymerase B2 K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D OE_4293R polD2; DNA-directed DNA polymerase D large subunit (intein-containing) K02322 polC; DNA polymerase II large subunit [EC:2.7.7.7]
D OE_4390F polD1; DNA-directed DNA polymerase D exonuclease subunit DP1 K02323 polB; DNA polymerase II small subunit [EC:2.7.7.7]
D OE_3305F rfcB; replication factor C large subunit K04800 rfcL; replication factor C large subunit
D OE_4142F rfcC; replication factor C small subunit K04801 rfcS; replication factor C small subunit
D OE_4195F rfcA; replication factor C small subunit K04801 rfcS; replication factor C small subunit
D OE_2304F gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D OE_2303F gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D OE_2301R top6A; DNA topoisomerase 6 subunit A K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D OE_2302R top6B; DNA topoisomerase 6 subunit B K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D OE_1528F topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D OE_4103R homolog to DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:hsl03036]
D OE_3386F DUF171 family protein K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D OE_2981F rad3a; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_4424R rad3b; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_1220F hstA; archaeal histone K24450 hmf; DNA-binding protein
D OE_4427R dpsA; ferritin K04047 dps; starvation-inducible DNA-binding protein
D OE_4509F nonhistone chromosomal protein K28135 mc1; chromosomal protein MC1
D OE_1515R smc; chromosome segregation protein Smc K03529 smc; chromosome segregation protein
D OE_1512R scpA; chromosome segregation and condensation protein ScpA K05896 scpA; segregation and condensation protein A
D OE_5212F sph1; SMC-like protein Sph1 K24719 sph1; smc-like protein Sph1
D OE_1319R ftsZ2; cell division protein FtsZ, type II K03531 ftsZ; cell division protein FtsZ
D OE_1559R ftsZ1; cell division protein FtsZ, type I K03531 ftsZ; cell division protein FtsZ
D OE_2378R parA1; ParA domain protein (fla operon protein ParA1) K03609 minD; septum site-determining protein MinD
D OE_3971R parA2; ParA domain protein K03609 minD; septum site-determining protein MinD
D OE_5021F parA3; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_6220R parA6b; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_7039F parA7; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_7100R parA6a; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_7162R parA8; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_8002F parA9; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_2626R apbC; Fe-S cluster carrier protein ApbC K03593 mrp; ATP-binding protein involved in chromosome partitioning
D OE_6023R Fido domain protein K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
C 03400 DNA repair and recombination proteins [BR:hsl03400]
D OE_1467R ogt; probable methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D OE_2907R phr2; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OE_3467R phr1; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D OE_3165R mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D OE_2814F DNA N-glycosylase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D OE_1589F nthB; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D OE_1890R nthA; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D OE_4165R pcn; DNA polymerase sliding clamp K04802 PCNA; proliferating cell nuclear antigen
D OE_2939R fen1; flap endonuclease Fen1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D OE_2298F ligB; DNA ligase (ATP) K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D OE_3010F rad25c; DNA repair helicase Rad25 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D OE_2981F rad3a; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_4424R rad3b; DNA repair helicase Rad3 K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D OE_1218F rpa2; replication protein A K07466 RFA1; replication factor A1
D OE_1715F NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OE_3899R NUDIX family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D OE_4610R dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D OE_2049R phr3; cryptochrome/photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D OE_2758R uracil-DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D OE_3906F udg; uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D OE_2870R DNA N-glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D OE_1304F apn1; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D OE_1543F nfi; endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7]
D OE_3905F UPF0215 family protein K09120 dU; endonuclease dU
D OE_4282F recJ1; single-stranded-DNA-specific exonuclease RecJ1 K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D OE_4699F uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D OE_4353R uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D OE_4344F uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D OE_4677F uvrD; repair helicase UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D OE_1272R mutS1b; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D OE_1286R mutS1a; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D OE_4183F mutS5a; DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2
D OE_1267R mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D OE_1770F rad50; DNA double-strand break repair ATPase Rad50 K03546 sbcC; DNA repair protein SbcC/Rad50
D OE_1769F mre11; DNA double-strand break repair protein Mre11 K03547 sbcD; DNA repair protein SbcD/Mre11
D OE_5328R UvrD/REP family helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D OE_5335R homolog to nuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D OE_4466R radA; DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D OE_3352R radB; DNA repair and recombination protein RadB K04484 radB; DNA repair protein RadB
D OE_4160F hjc; Holliday junction resolvase Hjc K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D OE_4325F hel308a; ATP-dependent DNA helicase Hel308 K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D OE_2304F gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D OE_2303F gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D OE_1528F topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D OE_4103R homolog to DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D OE_2475F polY; DNA-directed DNA polymerase Y K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D OE_2794R lhr; ATP-dependent DNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D OE_3328R nrdJ; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OE_4346R nrdA1; ribonucleoside-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D OE_4345R nrdB1; ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D OE_1529F DUF650/DUF651 domain protein K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:hsl03029]
D OE_3398F rnp1; ribonuclease P protein component 1 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D OE_2832R rnp2; ribonuclease P protein component 2 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D OE_2834R rnp3; ribonuclease P protein component 3 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D OE_4377R oapA; origin-associated GTP-binding protein OapA K03595 era; GTPase
D OE_4139R tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D OE_4118R leuS; leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D OE_4307F glyS; glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D OE_5203F argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D OE_2284F gatA; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D OE_1522F gatB; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D OE_2283F gatC; aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D OE_1737R dnaK; Hsp70-type molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D OE_1742R grpE; DnaJ/DnaK ATPase stimulator GrpE K03687 GRPE; molecular chaperone GrpE
D OE_1736R dnaJ; molecular chaperone DnaJ K03686 dnaJ; molecular chaperone DnaJ
D OE_1673F grx4; glutaredoxin K07390 grxD; monothiol glutaredoxin
D OE_2626R apbC; Fe-S cluster carrier protein ApbC K03593 mrp; ATP-binding protein involved in chromosome partitioning
D OE_1989F ctaB; protoheme IX geranylgeranyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D OE_3306R ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D OE_1254R SCO1/SenC/PrrC family protein K07152 SCO1; protein SCO1
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:hsl02000]
D OE_1202F ABC-type transport system ATP-binding/permease protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D OE_3270R ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/thiosulfate/molybdate) K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D OE_3269R ABC-type transport system permease protein (probable substrate sulfate/thiosulfate/molybdate) K15496 wtpB; molybdate/tungstate transport system permease protein
D OE_2348R sfuA; ABC-type transport system periplasmic substrate-binding protein (probable substrate iron) K02012 afuA; iron(III) transport system substrate-binding protein
D OE_2346R sfuB; ABC-type transport system permease protein (probable substrate iron) K02011 afuB; iron(III) transport system permease protein
D OE_2343R sfuC; ABC-type transport system ATP-binding protein (probable substrate iron) K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D OE_3641F thiB2; ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) K02064 thiB; thiamine transport system substrate-binding protein
D OE_4357F thiB1; ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) K02064 thiB; thiamine transport system substrate-binding protein
D OE_4358F thiP; ABC-type transport system permease protein (probable substrate thiamine) K02063 thiP; thiamine transport system permease protein
D OE_4359F thiQ; ABC-type transport system ATP-binding protein (probable substrate thiamine) K02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]
D OE_2196F chemotactic signal transduction system periplasmic substrate-binding protein K11069 potD; spermidine/putrescine transport system substrate-binding protein
D OE_3629R potD; ABC-type transport system periplasmic substrate-binding protein (probable substrate spermidine/putrescine) K11069 potD; spermidine/putrescine transport system substrate-binding protein
D OE_3625R potC; ABC-type transport system permease protein (probable substrate spermidine/putrescine) K11070 potC; spermidine/putrescine transport system permease protein
D OE_3627R potB; ABC-type transport system permease protein (probable substrate spermidine/putrescine) K11071 potB; spermidine/putrescine transport system permease protein
D OE_3631F potA; ABC-type transport system ATP-binding protein (probable substrate spermidine/putrescine) K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
D OE_5273R ABC-type transport system periplasmic substrate-binding protein K02055 ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein
D OE_5270R ABC-type transport system permease protein K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D OE_5272R ABC-type transport system permease protein K02053 ABC.SP.P; putative spermidine/putrescine transport system permease protein
D OE_5268R ABC-type transport system ATP-binding protein K02052 ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein
D OE_5166F ugpB; ABC-type transport system periplasmic substrate-binding protein (probable substrate glycerol-3-phosphate) K05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein
D OE_5168F ugpA; ABC-type transport system permease protein (probable substrate glycerol-3-phosphate) K05814 ugpA; sn-glycerol 3-phosphate transport system permease protein
D OE_5169F ugpE; ABC-type transport system permease protein (probable substrate glycerol-3-phosphate) K05815 ugpE; sn-glycerol 3-phosphate transport system permease protein
D OE_5170F ugpC; ABC-type transport system ATP-binding protein (probable substrate glycerol-3-phosphate) K05816 ugpC; sn-glycerol 3-phosphate transport system ATP-binding protein [EC:7.6.2.10]
D OE_2170R chemotactic signal transduction system periplasmic substrate-binding protein K07335 bmpA; basic membrane protein A and related proteins
D OE_2317R tsgA; ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) K07335 bmpA; basic membrane protein A and related proteins
D OE_2315R tsgB; ABC-type transport system permease protein (probable substrate sugar) K23535 nupB; general nucleoside transport system permease protein
D OE_2314R tsgC; ABC-type transport system permease protein (probable substrate sugar) K23536 nupC; general nucleoside transport system permease protein
D OE_2316R tsgD; ABC-type transport system ATP-binding protein (probable substrate sugar) K23537 nupA; general nucleoside transport system ATP-binding protein
D OE_1679R pstS2; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) K02040 pstS; phosphate transport system substrate-binding protein
D OE_4485R pstS1; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) K02040 pstS; phosphate transport system substrate-binding protein
D OE_1678R pstC2; ABC-type transport system permease protein (probable substrate phosphate) K02037 pstC; phosphate transport system permease protein
D OE_4483R pstC1; ABC-type transport system permease protein (probable substrate phosphate) K02037 pstC; phosphate transport system permease protein
D OE_1676R pstA2; ABC-type transport system permease protein (probable substrate phosphate) K02038 pstA; phosphate transport system permease protein
D OE_4480R pstA1; ABC-type transport system permease protein (probable substrate phosphate) K02038 pstA; phosphate transport system permease protein
D OE_1675R pstB2; ABC-type transport system ATP-binding protein (probable substrate phosphate) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D OE_4479R pstB1; ABC-type transport system ATP-binding protein (probable substrate phosphate) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D OE_3910R phnD; ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate/phosphonate) K02044 phnD; phosphonate transport system substrate-binding protein
D OE_3907R phnE; ABC-type transport system permease protein (probable substrate phosphate/phosphonate) K02042 phnE; phosphonate transport system permease protein
D OE_3908R phnC; ABC-type transport system ATP-binding protein (probable substrate phosphate/phosphonate) K02041 phnC; phosphonate transport system ATP-binding protein [EC:7.3.2.2]
D OE_4305R dppA1; ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D OE_4311F dppA3; ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D OE_4551F dppA2; ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D OE_4304R dppB1; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D OE_4313F dppB3; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D OE_4552F dppB2; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02033 ABC.PE.P; peptide/nickel transport system permease protein
D OE_4303R dppC1; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D OE_4316F dppC3; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D OE_4555F dppC2; ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D OE_4302R dppD1; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D OE_4317F dppD3; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D OE_4550F dppDF2; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D OE_4301R dppF1; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02032 ddpF; peptide/nickel transport system ATP-binding protein
D OE_4318F dppF3; ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) K02032 ddpF; peptide/nickel transport system ATP-binding protein
D OE_1480F ABC-type transport system periplasmic substrate-binding protein (probable substrate iron/cobalamin) K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D OE_4576F ABC-type transport system periplasmic substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D OE_4593R ABC-type transport system periplasmic substrate-binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D OE_4577F ABC-type transport system permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D OE_4591R ABC-type transport system permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D OE_4579F ABC-type transport system ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D OE_4587R ABC-type transport system ATP-binding protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D OE_2951R btuF; ABC-type transport system periplasmic substrate-binding protein (substrate cobalamin) K25034 btuF; cobalamin transport system substrate-binding protein
D OE_2952F btuC; ABC-type transport system permease protein (substrate cobalamin) K25027 btuC; cobalamin transport system permease protein
D OE_2955F btuD; ABC-type transport system ATP-binding protein (substrate cobalamin) K25028 btuD; cobalamin transport system ATP-binding protein [EC:7.6.2.8]
D OE_5147R znuA; ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) K09815 znuA; zinc transport system substrate-binding protein
D OE_5144R znuB; ABC-type transport system permease protein (probable substrate zinc) K09816 znuB; zinc transport system permease protein
D OE_5146R znuC; ABC-type transport system ATP-binding protein (probable substrate zinc) K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D OE_3318R cbiN; ABC-type transport system protein CbiN (probable substrate cobalt) K02009 cbiN; cobalt/nickel transport protein
D OE_3317R cbiQ; ABC-type transport system permease protein (probable substrate cobalt) K02008 cbiQ; cobalt/nickel transport system permease protein
D OE_3319R cbiM; ABC-type transport system permease protein (probable substrate cobalt) K02007 cbiM; cobalt/nickel transport system permease protein
D OE_3315R cbiO; ABC-type transport system ATP-binding protein (probable substrate cobalt) K02006 cbiO; cobalt/nickel transport system ATP-binding protein
D OE_4255F bioY; biotin transport protein BioY K03523 bioY; biotin transport system substrate-specific component
D OE_4257C1F bioN; ABC-type transport system permease protein (probable substrate biotin) K16783 bioN; biotin transport system permease protein
D OE_4256F bioM; ABC-type transport system ATP-binding protein (probable substrate biotin) K16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]
D OE_1695R ABC-type transport system permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D OE_1997F ABC-type transport system permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D OE_2032F ABC-type transport system permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D OE_2789R ABC-type transport system permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D OE_4336R ABC-type transport system permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D OE_5246R ABC-type transport system permease protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D OE_1693R probable ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_1704R ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_1994F ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_2026F ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_2787R ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_3661F ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_4339R ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_5245F ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_5264F ABC-type transport system ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D OE_1005F ABC-type transport system permease protein (probable substrate macrolides) K02004 ABC.CD.P; putative ABC transport system permease protein
D OE_1004F ABC-type transport system ATP-binding protein (probable substrate macrolides) K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D OE_2179F ABC-type transport system ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D OE_1781F sufC; Fe-S cluster assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D OE_5255R transport protein (probable substrate dicarboxylate) K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D OE_2063R MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D OE_2076F MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D OE_4110R MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D OE_4370R MATE efflux family protein K26937 dinF; MATE family, multidrug efflux pump
D OE_1265F major facilitator superfamily transport protein K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
D OE_1753R major facilitator superfamily transport protein K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D OE_6261R major facilitator superfamily transport protein K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D OE_7141R major facilitator superfamily transport protein K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D OE_3596F pchA1; ion channel pore / TrkA domain protein K10716 kch; voltage-gated potassium channel
D OE_4448R mgtE1; MgtE family transport protein (probable substrate magnesium) K07244 K07244; mgtE-like transporter
D OE_4449R mgtE2; MgtE family transport protein (probable substrate magnesium) K07244 K07244; mgtE-like transporter
D OE_3703R crcB1; putative fluoride ion transport protein CrcB K06199 crcB; fluoride exporter
D OE_3704R crcB2; putative fluoride ion transport protein CrcB K06199 crcB; fluoride exporter
D OE_4238R DUF21/CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D OE_5193F DUF21/CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D OE_2370R gufA; GufA family transport protein (probable substrate zinc) K07238 TC.ZIP; zinc transporter, ZIP family
D OE_3453R uncharacterized protein K07238 TC.ZIP; zinc transporter, ZIP family
D OE_3652F small multidrug export protein K03297 emrE; small multidrug resistance pump
D OE_6063F lctP; L-lactate permease K03303 lutP; lactate permease
D OE_1564R homolog to sodium/calcium antiporter K07301 yrbG; cation:H+ antiporter
D OE_4167R homolog to sodium/calcium antiporter K07301 yrbG; cation:H+ antiporter
D OE_2322F SSSF family transport protein K11928 putP; sodium/proline symporter
D OE_3960F nhaC2; probable NhaC-type sodium/proton antiporter K24446 arcD; arginine/ornithine antiporter
D OE_5204R arcD; arginine/ornithine antiporter K24446 arcD; arginine/ornithine antiporter
D OE_2841R trkH1; Trk-type transport system (probable substrate potassium) K03498 trkH; trk/ktr system potassium uptake protein
D OE_3422R trkH2; Trk-type transport system (probable substrate potassium) K03498 trkH; trk/ktr system potassium uptake protein
D OE_4599F trkH3; Trk-type transport system (probable substrate potassium) K03498 trkH; trk/ktr system potassium uptake protein
D OE_5301F trkH4; Trk-type transport system (probable substrate potassium) K03498 trkH; trk/ktr system potassium uptake protein
D OE_1290F trkA1; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_2838R trkA5; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_3710R trkA6; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_5051R trkA2; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_5100R trkA3; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_5106F trkA7; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_5130F trkA4; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_5298F trkA8; TrkA domain protein K03499 trkA; trk/ktr system potassium uptake protein
D OE_3950R uraA; xanthine/uracil permease family transport protein K06901 pbuG; adenine/guanine/hypoxanthine permease
D OE_3200R clc; chloride channel protein K03281 clcA; chloride channel protein, CIC family
D OE_1547R arsA2; ArsA family ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D OE_5440F arsA1; ArsA-type transport ATPase (probable substrate arsenite) K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D OE_1848R mrpB2; Mrp-type sodium/proton antiporter system subunit B2 K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D OE_1849R mrpB1; Mrp-type sodium/proton antiporter system subunit B1 K05566 mnhB; multicomponent Na+:H+ antiporter subunit B
D OE_1847R mrpC; Mrp-type sodium/proton antiporter system subunit C K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D OE_1841R mrpD2; Mrp-type sodium/proton antiporter system subunit D2 K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D OE_1842R mrpD1; Mrp-type sodium/proton antiporter system subunit D1 K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D OE_1844R mrpD3; Mrp-type sodium/proton antiporter system subunit D3 K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D OE_1854R mrpE; Mrp-type sodium/proton antiporter system subunit E K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D OE_1853R mrpF; Mrp-type sodium/proton antiporter system subunit F K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D OE_1852R mrpG; Mrp-type sodium/proton antiporter system subunit G K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D OE_4178R DUF165 family protein K09125 yhhQ; queuosine precursor transporter
D OE_1794R uncharacterized protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D OE_1249R homolog to cytochrome c-type biogenesis protein CcdA K06196 ccdA; cytochrome c-type biogenesis protein
D OE_2223F dmsA; dimethylsulfoxide reductase subunit A K07306 dmsA; anaerobic dimethyl sulfoxide reductase subunit A [EC:1.8.5.3]
D OE_2225F dmsB; dimethylsulfoxide reductase subunit B K00184 dmsB; dimethyl sulfoxide reductase iron-sulfur subunit
D OE_2227F dmsC; dimethylsulfoxide reductase subunit C K00185 dmsC; dimethyl sulfoxide reductase membrane subunit
C 02044 Secretion system [BR:hsl02044]
D OE_2397F flgB1; flagellin B1 K07324 flaA; archaeal flagellin FlaA
D OE_2398F flgB2; flagellin B2 K07324 flaA; archaeal flagellin FlaA
D OE_2469F flgA1; flagellin A1 K07324 flaA; archaeal flagellin FlaA
D OE_2695F flgX; flagellin flgX K07324 flaA; archaeal flagellin FlaA
D OE_2399F flgB3; flagellin B3 K07325 flaB; archaeal flagellin FlaB
D OE_2470F flgA2; flagellin A2 K07325 flaB; archaeal flagellin FlaB
D OE_2386R flaCE; fla cluster protein FlaCE K23986 flaCE; archaeal flagellar protein FlaCE
D OE_2385R flaF; fla cluster protein FlaF K07329 flaF; archaeal flagellar protein FlaF
D OE_2383R flaG; fla cluster protein FlaG K07330 flaG; archaeal flagellar protein FlaG
D OE_4607R flaG2; FlaG2 protein (homolog to fla cluster protein FlaG) K07330 flaG; archaeal flagellar protein FlaG
D OE_2381R flaH; fla cluster protein FlaH K07331 flaH; archaeal flagellar protein FlaH
D OE_2215R type II/IV secretion system ATPase protein K07332 flaI; archaeal flagellar protein FlaI
D OE_2380R flaI; flagellar motor/biogenesis protein FlaI K07332 flaI; archaeal flagellar protein FlaI
D OE_2212R type II/IV secretion system transmembrane protein K07333 flaJ; archaeal flagellar protein FlaJ
D OE_2379R flaJ; flagellar motor/biogenesis protein FlaJ K07333 flaJ; archaeal flagellar protein FlaJ
D OE_4201R pibD; prepilin/preflagellin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D OE_3784R secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D OE_3787R secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D OE_3418F secY; protein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D OE_4450R srp54; signal recognition particle 54K protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D OE_4454R ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D OE_1558R secE; protein translocase subunit SecE K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
D OE_2950R srp19; signal recognition particle 19K protein K03105 SRP19; signal recognition particle subunit SRP19
D OE_2186R tatA; Sec-independent protein translocase subunit TatA K03116 tatA; sec-independent protein translocase protein TatA
D OE_4181R tatC2; Sec-independent protein translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
D OE_4182F tatC1; Sec-independent protein translocase subunit TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:hsl02042]
D OE_4238R DUF21/CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D OE_5193F DUF21/CBS domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:hsl02022]
D OE_2086F receiver box response regulator K02483 K02483; two-component system, OmpR family, response regulator
D OE_2415R cheA; taxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D OE_2417R cheY; response regulator CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D OE_2416R cheB; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C 02035 Bacterial motility proteins [BR:hsl02035]
D OE_2415R cheA; taxis sensor histidine kinase CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
D OE_2374R cheW2; purine-binding taxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D OE_2419R cheW1; purine-binding taxis protein CheW K03408 cheW; purine-binding chemotaxis protein CheW
D OE_2410R cheC3; taxis cluster protein CheC K03410 cheC; chemotaxis protein CheC
D OE_2414R cheC1; taxis cluster protein CheC K03410 cheC; chemotaxis protein CheC
D OE_3280R cheC2; taxis cluster protein CheC K03410 cheC; chemotaxis protein CheC
D OE_2408R cheD; taxis cluster protein CheD K03411 cheD; chemotaxis protein CheD [EC:3.5.1.44]
D OE_2406R cheR; protein-glutamate O-methyltransferase CheR K00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]
D OE_2416R cheB; protein-glutamate methylesterase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
D OE_2417R cheY; response regulator CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
D OE_1536R mpcT; transducer protein MpcT K03406 mcp; methyl-accepting chemotaxis protein
D OE_1929R htr16; transducer protein Htr16 K03406 mcp; methyl-accepting chemotaxis protein
D OE_2168R htrVI; transducer protein HtrVI K03406 mcp; methyl-accepting chemotaxis protein
D OE_2195F htr18; transducer protein Htr18 K03406 mcp; methyl-accepting chemotaxis protein
D OE_2392R htr15; transducer protein Htr15 K03406 mcp; methyl-accepting chemotaxis protein
D OE_3167F htrVIII; transducer protein HtrVIII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3347F htrI; transducer protein HtrI K03406 mcp; methyl-accepting chemotaxis protein
D OE_3473F htrVII; transducer protein HtrVII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3474R cosT; transducer protein CosT K03406 mcp; methyl-accepting chemotaxis protein
D OE_3481R htrII; transducer protein HtrII K03406 mcp; methyl-accepting chemotaxis protein
D OE_3611R basT; transducer protein BasT K03406 mcp; methyl-accepting chemotaxis protein
D OE_3150R hemAT; transducer protein HemAT K06595 hemAT; heam-based aerotactic trancducer
D OE_2397F flgB1; flagellin B1 K07324 flaA; archaeal flagellin FlaA
D OE_2398F flgB2; flagellin B2 K07324 flaA; archaeal flagellin FlaA
D OE_2469F flgA1; flagellin A1 K07324 flaA; archaeal flagellin FlaA
D OE_2695F flgX; flagellin flgX K07324 flaA; archaeal flagellin FlaA
D OE_2399F flgB3; flagellin B3 K07325 flaB; archaeal flagellin FlaB
D OE_2470F flgA2; flagellin A2 K07325 flaB; archaeal flagellin FlaB
D OE_2386R flaCE; fla cluster protein FlaCE K23986 flaCE; archaeal flagellar protein FlaCE
D OE_2385R flaF; fla cluster protein FlaF K07329 flaF; archaeal flagellar protein FlaF
D OE_2383R flaG; fla cluster protein FlaG K07330 flaG; archaeal flagellar protein FlaG
D OE_4607R flaG2; FlaG2 protein (homolog to fla cluster protein FlaG) K07330 flaG; archaeal flagellar protein FlaG
D OE_2381R flaH; fla cluster protein FlaH K07331 flaH; archaeal flagellar protein FlaH
D OE_2215R type II/IV secretion system ATPase protein K07332 flaI; archaeal flagellar protein FlaI
D OE_2380R flaI; flagellar motor/biogenesis protein FlaI K07332 flaI; archaeal flagellar protein FlaI
D OE_2212R type II/IV secretion system transmembrane protein K07333 flaJ; archaeal flagellar protein FlaJ
D OE_2379R flaJ; flagellar motor/biogenesis protein FlaJ K07333 flaJ; archaeal flagellar protein FlaJ
D OE_4201R pibD; prepilin/preflagellin peptidase K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:hsl04812]
D OE_1319R ftsZ2; cell division protein FtsZ, type II K03531 ftsZ; cell division protein FtsZ
D OE_1559R ftsZ1; cell division protein FtsZ, type I K03531 ftsZ; cell division protein FtsZ
D OE_1414R ftsZ4; FtsZ family protein, type III K22222 cetZ; tubulin-like protein CetZ
D OE_3718F ftsZ3; FtsZ family protein, type III K22222 cetZ; tubulin-like protein CetZ
D OE_5142F ftsZ5; FtsZ family protein, noncanonical K22222 cetZ; tubulin-like protein CetZ
D OE_6329R ftsZ6; FtsZ family protein, noncanonical K22222 cetZ; tubulin-like protein CetZ
D OE_6337R ftsZ7; FtsZ family protein, noncanonical K22222 cetZ; tubulin-like protein CetZ
D OE_2378R parA1; ParA domain protein (fla operon protein ParA1) K03609 minD; septum site-determining protein MinD
D OE_3971R parA2; ParA domain protein K03609 minD; septum site-determining protein MinD
D OE_5021F parA3; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_6220R parA6b; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_7039F parA7; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_7100R parA6a; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_7162R parA8; ParA domain protein K03496 parA; chromosome partitioning protein
D OE_8002F parA9; ParA domain protein K03496 parA; chromosome partitioning protein
C 04147 Exosome [BR:hsl04147]
D OE_2640F eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D OE_2745R pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D OE_1495R pykA; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D OE_3693F ppiA; CYPL-type peptidylprolyl isomerase K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]
D OE_3371F homolog to translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4721R tef1a1; translation elongation factor aEF-1 alpha subunit K03231 EEF1A; elongation factor 1-alpha
D OE_4729R tef2; translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D OE_1737R dnaK; Hsp70-type molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D OE_3792F pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D OE_2939R fen1; flap endonuclease Fen1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D OE_2458R guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D OE_3868R rps31e; 30S ribosomal protein S31e K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D OE_3112R cdc48b; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_3356F cdc48a; AAA-type ATPase (CDC48 subfamily) K13525 VCP; transitional endoplasmic reticulum ATPase
D OE_4065R hit1; histidine triad family protein (homolog to bis(5'-nucleosyl)-tetraphosphatase) K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D OE_2912F acs3; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_3891R acs5; acyl-CoA synthetase K01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
D OE_2011R acaB1; acetyl-CoA C-acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_2358F acaB2; acetyl-CoA C-acetyltransferase catalytic subunit K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D OE_4159F ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D OE_3425F adk1; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D OE_1840R apt1; purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase) K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D OE_4419R argH; argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D OE_4420R argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D OE_2173F metB2; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_2681F metB1; cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) K01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]
D OE_2020F fbp; fructose-1,6-bisphosphatase K03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]
D OE_3762R glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D OE_3922R glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D OE_4262F hemB; porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D OE_3495R cad; probable pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D OE_5192R aph; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
D OE_4408F serA1; phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D OE_4116F lpdA; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D OE_4007F etfA; electron transfer flavoprotein alpha subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D OE_1270F gdhA3; glutamate dehydrogenase (NAD) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_1943F gdhA1; glutamate dehydrogenase (NADP) K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_2728R gdhA2; glutamate dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D OE_2500R tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:hsl02048]
D OE_1178F rmeR; type I site-specific deoxyribonuclease subunit RmeR K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D OE_1177F rmeS; type I site-specific deoxyribonuclease subunit RmeS K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D OE_3197F zim; CTAG modification methylase K24451 zim; modification methylase
D OE_6138F homolog to restriction system mrr K07448 mrr; restriction system protein
D OE_5179B1F RelE family protein K06218 relE; mRNA interferase RelE/StbE
D OE_5410A1R RelE family protein K06218 relE; mRNA interferase RelE/StbE
D OE_1319R ftsZ2; cell division protein FtsZ, type II K03531 ftsZ; cell division protein FtsZ
D OE_1559R ftsZ1; cell division protein FtsZ, type I K03531 ftsZ; cell division protein FtsZ
D OE_2652F gltS; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D OE_3796R nob1; rRNA maturation endonuclease Nob1 K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C 04030 G protein-coupled receptors [BR:hsl04030]
D OE_3106F bop; bacteriorhodopsin K04641 bop; bacteriorhodopsin
D OE_1299R hop; halorhodopsin K04642 hop; halorhodopsin
D OE_3348F sopI; sensory rhodopsin I K04643 sop; sensory rhodopsin
D OE_3480R sopII; sensory rhodopsin II K04643 sop; sensory rhodopsin
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:hsl04090]
C 01504 Antimicrobial resistance genes [BR:hsl01504]
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsl00537]
D OE_5192R aph; alkaline phosphatase K01077 E3.1.3.1; alkaline phosphatase [EC:3.1.3.1]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:hsl03100]
D OE_tRNAAla1 tRNAAla1; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAAla2 tRNAAla2; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAAla3 tRNAAla3; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAAla4 tRNAAla4; tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D OE_tRNAArg1 tRNAArg1; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg2 tRNAArg2; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg3 tRNAArg3; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg4 tRNAArg4; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAArg5 tRNAArg5; tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D OE_tRNAAsn tRNAAsn; tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D OE_tRNAAsp tRNAAsp; tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D OE_tRNACys tRNACys; tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D OE_tRNAGln1 tRNAGln1; tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D OE_tRNAGln2 tRNAGln2; tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D OE_tRNAGlu1 tRNAGlu1; tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D OE_tRNAGlu2 tRNAGlu2; tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D OE_tRNAGly1 tRNAGly1; tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D OE_tRNAGly2 tRNAGly2; tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D OE_tRNAGly3 tRNAGly3; tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D OE_tRNAHis tRNAHis; tRNA-His K14226 tRNA-His; tRNA His
D OE_tRNAIle tRNAIle; tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D OE_tRNALeu1 tRNALeu1; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu2 tRNALeu2; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu3 tRNALeu3; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu4 tRNALeu4; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALeu5 tRNALeu5; tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D OE_tRNALys1 tRNALys1; tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D OE_tRNALys2 tRNALys2; tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D OE_tRNAIniMet1 tRNAIniMet1; tRNA-Met K14230 tRNA-Met; tRNA Met
D OE_tRNAIniMet2 tRNAIniMet2; tRNA-Met K14230 tRNA-Met; tRNA Met
D OE_tRNAMet tRNAMet; tRNA-Met K14230 tRNA-Met; tRNA Met
D OE_tRNAPhe tRNAPhe; tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D OE_tRNAPro1 tRNAPro1; tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D OE_tRNAPro2 tRNAPro2; tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D OE_tRNAPro3 tRNAPro3; tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D OE_tRNASer1 tRNASer1; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNASer2 tRNASer2; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNASer3 tRNASer3; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNASer4 tRNASer4; tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D OE_tRNAThr1 tRNAThr1; tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D OE_tRNAThr2 tRNAThr2; tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D OE_tRNAThr3 tRNAThr3; tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D OE_tRNATrp tRNATrp; tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D OE_tRNATyr tRNATyr; tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D OE_tRNAVal1 tRNAVal1; tRNA-Val K14237 tRNA-Val; tRNA Val
D OE_tRNAVal2 tRNAVal2; tRNA-Val K14237 tRNA-Val; tRNA Val
D OE_tRNAVal3 tRNAVal3; tRNA-Val K14237 tRNA-Val; tRNA Val
D OE_RRNA16S rRNA16S; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D OE_RRNA23S rRNA23S; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D OE_RRNA5S rRNA5S; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D OE_RNASEP RNAseP; RNase P RNA K01978 rnpB; RNase P catalytic RNA component
D OE_SRPRNA RNA7S; signal recognition particle 7S RNA K01983 ffs; signal recognition particle 4.5S RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D OE_1698R probable oxidoreductase (aldo-keto reductase family protein) K06222 dkgB; 2,5-diketo-D-gluconate reductase B [EC:1.1.1.346]
D OE_4655R npdG; F420H2:NADP oxidoreductase K06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]
D OE_2720R FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) K00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]
D OE_1936R flavin-containing amine-oxidoreductase K18208 RNLS; renalase [EC:1.6.3.5]
D OE_2199F qor2; NADPH:quinone reductase K00359 qorA; NADPH:quinone reductase [EC:1.6.5.5]
D OE_2693F msrA; peptide methionine sulfoxide reductase MsrA (S-form specific) K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D OE_3008F msrB; peptide methionine sulfoxide reductase MsrB (R-form specific) K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D OE_4196R glutathione S-transferase K07393 ECM4; glutathionyl-hydroquinone reductase [EC:1.8.5.7]
D OE_2717R homolog to peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D OE_4240F homolog to peroxiredoxin K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D OE_3102R brp; beta-carotene 15,15'-dioxygenase Brp K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]
D OE_3980R blh; beta-carotene 15,15'-dioxygenase Blh K21817 blh; beta-carotene 15,15'-dioxygenase [EC:1.13.11.63]
D OE_5098F iucD; probable 1,3-diaminopropane N-3-monooxygenase K27501 alcA; putrescine N-hydroxylase [EC:1.14.13.252]
D OE_5436R arsC; arsenate reductase (glutaredoxin) K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D OE_1147R pimT1; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D OE_2613R dph5; diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D OE_3059F dhs; deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D OE_3748R arcS; archaeosine synthase K07557 tgtA2; archaeosine synthase alpha-subunit [EC:2.6.1.97 2.6.1.-]
D OE_3726F TIGR01210 family protein K06936 raSEA; archaeosine synthase beta-subunit [EC:2.6.1.-]
D OE_2989R DisA-N domain protein K18672 dacA; diadenylate cyclase [EC:2.7.7.85]
D OE_1140R ubaA; SAMP-activating enzyme E1 K22837 ubaA; SAMP-activating enzyme [EC:2.7.7.100]
D OE_2503R pgsA2; CDP-alcohol 1-archaetidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D OE_3015F thioesterase domain protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D OE_1285F nucS1; endonuclease NucS K07503 nucS; endonuclease [EC:3.1.-.-]
D OE_3783F nucS2; endonuclease NucS K07503 nucS; endonuclease [EC:3.1.-.-]
D OE_3930R ridA; enamine/imine deaminase K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D OE_1358R moxR; AAA-type ATPase (MoxR subfamily) K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D OE_1461R S-adenosylmethionine hydroxide adenosyltransferase family protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D OE_2821F nnrDE; bifunctional NAD(P)H-hydrate repair enzyme Nnr K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D OE_2081R rtcA; RNA 3'-terminal phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
D OE_4082F cpx; P-type transport ATPase (probable substrate copper/metal cation) K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D OE_1245F cadA; P-type transport ATPase (probable substrate zinc/cadmium) K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
D OE_6062R DUF162 family protein K00782 lldG; L-lactate dehydrogenase complex protein LldG
C 99982 Energy metabolism
D OE_4324R fer6; ferredoxin (4Fe-4S) K05337 fer; ferredoxin
D OE_4465F iscU; iron-sulfur cluster assembly protein K04488 iscU; nitrogen fixation protein NifU and related proteins
D OE_4005F etfB; electron transfer flavoprotein beta subunit K03521 fixA; electron transfer flavoprotein beta subunit
D OE_3073R dodecin K09165 K09165; dodecin
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
D OE_1326R UPF0104 family protein K07027 K07027; glycosyltransferase 2 family protein
D OE_1606R UPF0104 family protein K07027 K07027; glycosyltransferase 2 family protein
C 99987 Cofactor metabolism
D OE_2219R mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein MobB K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
C 99999 Others
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D OE_2502R cro/C1 family transcription regulator K03627 MBF1; putative transcription factor
D OE_1162R cspA1; cold shock protein K03704 cspA; cold shock protein
D OE_3582F cspA2; cold shock protein K03704 cspA; cold shock protein
D OE_3142R lsm; RNA-binding protein Lsm K04796 RUXX; small nuclear ribonucleoprotein
D OE_1577R HTH domain protein K07743 K07743; transcriptional regulator
D OE_2306F DUF293 domain protein K07744 K07744; transcriptional regulator
C 99974 Translation
D OE_2676R putative tRNA-specific adenosine deaminase K07572 K07572; putative nucleotide binding protein
D OE_4527R beta-lactamase domain protein K07577 K07577; putative mRNA 3-end processing factor
D OE_2259F probable rRNA methyltransferase K07579 K07579; putative methylase
D OE_2682A1R small CPxCG-related zinc finger protein K07580 K07580; Zn-ribbon RNA-binding protein
D OE_2845R DUF54 family protein K07581 K07581; RNA-binding protein
D OE_3814R uncharacterized protein K07585 K07585; tRNA methyltransferase
C 99975 Protein processing
D OE_1274R hypE2; hydrogenase expression/formation protein K04655 hypE; hydrogenase expression/formation protein HypE
D OE_5190R hypE1; hydrogenase expression/formation protein K04655 hypE; hydrogenase expression/formation protein HypE
D OE_1629F MiaB-like tRNA modifying enzyme K07398 K07398; conserved protein with predicted RNA binding PUA domain
C 99976 Replication and repair
D OE_4189F UPF0213 family protein K07461 K07461; putative endonuclease
D OE_1058R ISH9-type transposase ISH1 K07481 K07481; transposase, IS5 family
D OE_1572R ISH9-type transposase ISH1 K07481 K07481; transposase, IS5 family
D OE_2886R ISH9-type transposase ISH1 K07481 K07481; transposase, IS5 family
D OE_5339R ISH9-type transposase ISH1 K07481 K07481; transposase, IS5 family
D OE_1031F ISH10-type transposase ISH10 K07484 K07484; transposase
D OE_1094R ISH10-type transposase ISH10 K07484 K07484; transposase
D OE_5260F ISH10-type transposase ISH10 K07484 K07484; transposase
D OE_6133R ISH10-type transposase ISH10 K07484 K07484; transposase
D OE_6217F ISH10-type transposase ISH10 K07484 K07484; transposase
D OE_7097F ISH10-type transposase ISH10 K07484 K07484; transposase
D OE_1073F IS200-type transposase ISH12 K07491 rayT; REP-associated tyrosine transposase
D OE_1439F IS200-type transposase ISH22 K07491 rayT; REP-associated tyrosine transposase
D OE_4728F IS200-type transposase ISH34 K07491 rayT; REP-associated tyrosine transposase
D OE_5063R IS200-type transposase ISH35 K07491 rayT; REP-associated tyrosine transposase
D OE_1019R IS1341-type transposase ISH37 K07496 K07496; putative transposase
D OE_1040R IS1341-type transposase ISH38 K07496 K07496; putative transposase
D OE_1070R IS1341-type transposase ISH39 K07496 K07496; putative transposase
D OE_1074F IS1341-type transposase ISH12 K07496 K07496; putative transposase
D OE_1440F IS1341-type transposase ISH22 K07496 K07496; putative transposase
D OE_4727R IS1341-type transposase ISH34 K07496 K07496; putative transposase
D OE_5102R IS1341-type transposase HsIRS6 K07496 K07496; putative transposase
D OE_6034F IS1341-type transposase ISH40 K07496 K07496; putative transposase
D OE_6089R IS1341-type transposase ISH41 K07496 K07496; putative transposase
D OE_6285F IS1341-type transposase ISH36 K07496 K07496; putative transposase
D OE_5183R ISH14-type transposase ISH33 K07498 K07498; putative transposase
D OE_6115F ISH14-type transposase ISH29 K07498 K07498; putative transposase
D OE_1045F homolog to ISH16-type transposase K07499 K07499; putative transposase
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D OE_2113R transport protein (probable substrate phosphate/sulfate) K03306 TC.PIT; inorganic phosphate transporter, PiT family
D OE_4236F transport protein (probable substrate phosphate/sulfate) K03306 TC.PIT; inorganic phosphate transporter, PiT family
D OE_6195F transport protein (probable substrate phosphate/sulfate) K03306 TC.PIT; inorganic phosphate transporter, PiT family
D OE_7075F transport protein (probable substrate phosphate/sulfate) K03306 TC.PIT; inorganic phosphate transporter, PiT family
D OE_3511F SSSF family transport protein K03307 TC.SSS; solute:Na+ symporter, SSS family
D OE_3171F SNF family transport protein K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D OE_3173F SNF family transport protein K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D OE_5143F SNF family transport protein K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D OE_7187F YidE family protein K07085 K07085; putative transport protein
D OE_8018F YidE family protein K07085 K07085; putative transport protein
C 99978 Cell growth
D OE_2100R SpoVR family protein K06415 spoVR; stage V sporulation protein R
D OE_1539F uncharacterized protein K28349 cdpA; cell division protein A
D OE_2427F PRC domain protein K28350 cdpB; cell division protein B
D OE_3798R PRC domain protein K28350 cdpB; cell division protein B
D OE_4713R sepF; probable SepF protein K09152 sepF; cell division protein SepF
C 99993 Cell motility
D OE_2402F cheF1; taxis protein CheF1 K09156 cheF; taxis protein CheF
D OE_2404R cheF2; taxis protein CheF2 K09156 cheF; taxis protein CheF
D OE_2401F HEAT-PBS family taxis protein K22221 K22221; HEAT repeat-containing taxis protein
D OE_1186A1F DUF1628 domain protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D OE_3768F DUF1628 domain protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D OE_3996R DUF1628 domain protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D OE_4050F DUF1628 domain protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D OE_6130F DUF1628 domain protein K23255 pilA; archaeal type IV pilus assembly protein PilA
D OE_3612R basB; chemotactic signal transduction system periplasmic substrate-binding protein BasB K23315 basB; chemotactic signal transduction system substrate-binding protein BasB
D OE_3476R cosB; chemotactic signal transduction system periplasmic substrate-binding protein CosB K23316 cosB; chemotactic signal transduction system substrate-binding protein CosB
C 99995 Signaling proteins
D OE_5055F UspA domain protein K23347 kdpQ; probable Kdp system regulatory protein
D OE_2104R prkA1; probable PrkA-type serine/threonine protein kinase K07180 prkA; serine protein kinase
D OE_3815R probable DNA-binding protein K06875 PDCD5; programmed cell death protein 5
D OE_5124R gvpD2; regulatory protein GvpD K23307 gvpD; gas vesicle operon resressor
D OE_7033R gvpD1; regulatory protein GvpD K23307 gvpD; gas vesicle operon resressor
C 99992 Structural proteins
D OE_5125F gvpA2; gas-vesicle protein GvpA K23262 gvpA; gas vesicle structural protein
D OE_7034F gvpA1; gas-vesicle protein GvpA K23262 gvpA; gas vesicle structural protein
D OE_5127F gvpC2; gas-vesicle protein GvpC K23263 gvpC; gas vesicle minor protein
D OE_7036F gvpC1; gas-vesicle protein GvpC K23263 gvpC; gas vesicle minor protein
D OE_4759F csg; S-layer glycoprotein K26284 csg; S-layer glycoprotein
C 99994 Others
D OE_1674R phoU2; transcription regulator (homolog to phosphate uptake regulator) K02039 phoU; phosphate transport system protein
D OE_1143R moeA2; molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
B
B 09194 Poorly characterized
C 99996 General function prediction only
D OE_4671R arNOG04375 family protein (homolog to PilT-type ATPase) K06865 K06865; ATPase
D OE_5286R probable DEAD/DEAH box helicase K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D OE_3369F HAD superfamily hydrolase K07025 K07025; putative hydrolase of the HAD superfamily
D OE_1782F sufB1; SufB domain protein K09014 sufB; Fe-S cluster assembly protein SufB
D OE_1783F sufB2; SufB domain protein K09015 sufD; Fe-S cluster assembly protein SufD
D OE_3286F tatD; TatD-related deoxyribonuclease K07049 K07049; TatD-related deoxyribonuclease
D OE_3682F fxsA; FxsA domain protein K07113 fxsA; UPF0716 protein FxsA
D OE_4320R UPF0148 family protein K07143 K07143; UPF0148 protein
D OE_2597R DUF112 family protein K08971 K08971; putative membrane protein
D OE_2551F DUF368 family protein K08974 K08974; putative membrane protein
D OE_1582R DUF373 family protein K08975 K08975; putative membrane protein
D OE_4011R DUF373 family protein K08975 K08975; putative membrane protein
D OE_2003R DUF420 family protein K08976 K08976; putative membrane protein
D OE_3138F DUF420 family protein K08976 K08976; putative membrane protein
D OE_1365F DUF2070 family protein K08979 K08979; putative membrane protein
D OE_2930R DUF304 domain protein K08981 K08981; putative membrane protein
D OE_5134F DUF2078 family protein K08982 K08982; putative membrane protein
C 99997 Function unknown
D OE_1752F PAC2 family protein K06869 K06869; uncharacterized protein
D OE_2373F DRTGG domain protein K06873 K06873; uncharacterized protein
D OE_1317F HD family hydrolase K06885 K06885; uncharacterized protein
D OE_3188R HD family hydrolase K06885 K06885; uncharacterized protein
D OE_4504F HD family hydrolase K06885 K06885; uncharacterized protein
D OE_2863R YyaL family protein K06888 K06888; uncharacterized protein
D OE_3681R YyaL family protein K06888 K06888; uncharacterized protein
D OE_3039F uncharacterized protein K06889 K06889; uncharacterized protein
D OE_1549F DUF1486 family protein K06893 K06893; uncharacterized protein
D OE_1918R YneT family protein K06929 K06929; uncharacterized protein
D OE_4294R DUF296 family protein K06934 K06934; uncharacterized protein
D OE_1445R uncharacterized protein K06940 K06940; uncharacterized protein
D OE_1793F HD family hydrolase K06950 K06950; uncharacterized protein
D OE_1812R probable phosphoesterase K06953 K06953; uncharacterized protein
D OE_2798R rpe; rpa-associated phosphoesterase K06953 K06953; uncharacterized protein
D OE_4537R homolog to photosystem I biogenesis protein BtpA K06971 K06971; uncharacterized protein
D OE_3940F AstE family protein K06987 K06987; uncharacterized protein
D OE_3118F RND superfamily permease K07003 K07003; uncharacterized protein
D OE_2696F FMN-binding domain protein K07005 K07005; uncharacterized protein
D OE_3132F FMN-binding domain protein K07005 K07005; uncharacterized protein
D OE_3304R FMN-binding domain protein K07005 K07005; uncharacterized protein
D OE_7219R FMN-binding domain protein K07005 K07005; uncharacterized protein
D OE_3578R uncharacterized protein K07018 K07018; uncharacterized protein
D OE_1592R beta-lactamase domain protein K07041 K07041; uncharacterized protein
D OE_1455R amidohydrolase family protein K07045 K07045; uncharacterized protein
D OE_1124R homolog to endonuclease VapC K07065 K07065; uncharacterized protein
D OE_5042R homolog to endonuclease VapC K07065 K07065; uncharacterized protein
D OE_6047A1R homolog to endonuclease VapC K07065 K07065; uncharacterized protein
D OE_1806R TRAP-type transport system periplasmic substrate-binding protein K07080 K07080; uncharacterized protein
D OE_6201F DUF81 family protein K07090 K07090; uncharacterized protein
D OE_7081F DUF81 family protein K07090 K07090; uncharacterized protein
D OE_4429F MJ0936 family phosphodiesterase K07095 K07095; uncharacterized protein
D OE_4539R uncharacterized protein K07097 K07097; uncharacterized protein
D OE_1504F gptA1; probable phosphoribosyltransferase K07101 K07101; uncharacterized protein
D OE_4222F ACT domain protein K07103 K07103; uncharacterized protein
D OE_6192F DUF4341/DUF395 family protein K07112 K07112; uncharacterized protein
D OE_6194F DUF4341/DUF395 family protein K07112 K07112; uncharacterized protein
D OE_7072F DUF4341/DUF395 family protein K07112 K07112; uncharacterized protein
D OE_7074F DUF4341/DUF395 family protein K07112 K07112; uncharacterized protein
D OE_4012F uncharacterized protein K07129 K07129; uncharacterized protein
D OE_3439F MOSC domain protein K07140 K07140; MOSC domain-containing protein
D OE_3927F DUF418 domain protein K07148 K07148; uncharacterized protein
D OE_3875R DUF188 family protein K07158 K07158; uncharacterized protein
D OE_1816R PAC2 family protein K07159 K07159; uncharacterized protein
D OE_4374R oapC; origin-associated protein OapC K07163 K07163; uncharacterized protein
D OE_4643R DUF151 family protein K08999 K08999; uncharacterized protein
D OE_3520F uncharacterized protein K09004 K09004; uncharacterized protein
D OE_1201F DUF192 family protein K09005 K09005; uncharacterized protein
D OE_1362R DUF192 family protein K09005 K09005; uncharacterized protein
D OE_4568R AMMECR1 domain protein K09141 K09141; uncharacterized protein
D OE_4462F DUF424 family protein K09148 K09148; uncharacterized protein
D OE_4140R DUF460 domain protein K09150 K09150; uncharacterized protein
D OE_2187F HD family hydrolase K09163 K09163; uncharacterized protein
D OE_2082F DUF1684 family protein K09164 K09164; uncharacterized protein
D OE_3456F DUF2071 family protein K09166 K09166; uncharacterized protein
D OE_2934R DUF304 domain protein K09167 K09167; uncharacterized protein
D OE_2595F YcgG family protein K09190 K09190; uncharacterized protein
D OE_4661R UPF0146 family protein K09713 K09713; uncharacterized protein
D OE_2806F DUF357 family protein K09728 K09728; uncharacterized protein
D OE_3004R UPF0179 family protein K09730 K09730; uncharacterized protein
D OE_2294R UPF0212 family protein K09731 K09731; uncharacterized protein
D OE_2813R UPF0212 family protein K09731 K09731; uncharacterized protein
D OE_4444F UPF0201 family protein K09736 K09736; uncharacterized protein
D OE_1587F DUF371 family protein K09738 K09738; uncharacterized protein
D OE_4376R oapB; origin-associated protein OapB K09743 K09743; uncharacterized protein
D OE_7174R DUF790 family protein K09744 K09744; uncharacterized protein
D OE_8009R DUF790 family protein K09744 K09744; uncharacterized protein
D OE_2800R rpap1; rpa-associated protein K09746 K09746; uncharacterized protein
D OE_4025F rpap3; rpa-associated protein K09746 K09746; uncharacterized protein
D OE_3002R DUF309 family protein K09763 K09763; uncharacterized protein
D OE_2102R UPF0229 family protein K09786 K09786; uncharacterized protein
D OE_2580F UPF0434 family protein K09791 K09791; uncharacterized protein
D OE_4080F uncharacterized protein K09792 K09792; uncharacterized protein
D OE_2653R DUF456 family protein K09793 K09793; uncharacterized protein
D OE_4633F SIMPL domain protein K09807 K09807; uncharacterized protein
D OE_2740F ribonuclease H domain protein K07502 yprB; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: September 4, 2025