+F Repair protein KO
#
DNA Repair and Recombination Proteins - Homalodisca vitripennis (glassy-winged sharpshooter)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 124360405 activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 124371862 LOW QUALITY PROTEIN: activating signal cointegrator 1 complex subunit 3-like K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 124371107 LOW QUALITY PROTEIN: deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D 124361862 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 124359334 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 124374971 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 124362394 probable DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E 124352877 single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 124369218 methyl-CpG-binding domain protein 4-like isoform X1 K10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]
D AP endonucleases
E 124360242 DNA-(apurinic or apyrimidinic site) endonuclease isoform X1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 124370666 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 124362054 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 124375133 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 124355568 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
F 124362770 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 124353195 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit 1-like K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 124355301 LOW QUALITY PROTEIN: DNA polymerase epsilon catalytic subunit A-like K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 124373482 DNA polymerase epsilon subunit 2 isoform X1 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 124369301 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 124368956 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 124357629 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 124366073 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 124367333 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 124372526 LOW QUALITY PROTEIN: DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 124353086 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 124357295 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 124358407 LOW QUALITY PROTEIN: DNA ligase 3-like K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 124371957 probable tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 124363123 probable tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 124354159 aprataxin-like K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 124354732 LOW QUALITY PROTEIN: bifunctional polynucleotide phosphatase/kinase K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 124353120 DNA polymerase lambda-like K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 124368392 poly [ADP-ribose] polymerase K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 124363670 UV excision repair protein RAD23 homolog A isoform X1 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 124362577 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 124372768 cullin-4A-like K10609 CUL4; cullin 4
F 124363307 LOW QUALITY PROTEIN: cullin-4B-like K10609 CUL4; cullin 4
F 124364607 DNA damage-binding protein 2-like K10140 DDB2; DNA damage-binding protein 2
F 124364609 DNA damage-binding protein 2-like K10140 DDB2; DNA damage-binding protein 2
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 124362860 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 124359361 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 124364132 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 124360187 DNA-directed RNA polymerase II subunit Rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 124371429 LOW QUALITY PROTEIN: DNA-directed RNA polymerases I, II, and III subunit RPABC1-like K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 124354652 DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 124357153 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 124372424 DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 124360455 DNA-directed RNA polymerase II subunit RPB9 isoform X1 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 124368120 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 124371410 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 124372384 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 124361985 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 124362577 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 124372768 cullin-4A-like K10609 CUL4; cullin 4
F 124363307 LOW QUALITY PROTEIN: cullin-4B-like K10609 CUL4; cullin 4
F 124368789 DNA excision repair protein ERCC-8-like K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F 124354479 DNA excision repair protein ERCC-6-like K10841 ERCC6; DNA excision repair protein ERCC-6
F 124359238 UV-stimulated scaffold protein A-like K23720 UVSSA; UV-stimulated scaffold protein A
F 124370803 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124370908 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124372835 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124374950 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124374951 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366115 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366116 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366117 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366118 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366119 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366120 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366121 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366122 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366123 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366124 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366507 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366580 transcription elongation factor 1 homolog isoform X1 K25829 ELOF1; transcription elongation factor 1
F 124366581 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366582 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
F 124366931 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 124371153 general transcription and DNA repair factor IIH helicase subunit XPB-like K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 124365902 general transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 124372084 LOW QUALITY PROTEIN: general transcription and DNA repair factor IIH helicase subunit XPD-like K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 124365010 general transcription and DNA repair factor IIH helicase subunit XPD-like K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 124366155 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 124359469 general transcription factor IIH subunit 3 isoform X1 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 124354656 LOW QUALITY PROTEIN: general transcription factor IIH subunit 4-like K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 124363135 general transcription factor IIH subunit 5-like K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 124363141 general transcription factor IIH subunit 5-like K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 124365906 LOW QUALITY PROTEIN: cyclin-dependent kinase 7-like K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 124366736 cyclin-dependent kinase 7-like K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 124366346 cyclin-H K06634 CCNH; cyclin H
E 124366391 cyclin-H-like isoform X1 K06634 CCNH; cyclin H
E 124366392 cyclin-H-like K06634 CCNH; cyclin H
E 124355449 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 124364852 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 124367849 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Other NER factors
E 124355387 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 124362476 DNA repair endonuclease XPF isoform X1 K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 124367333 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 124372149 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 124364798 cullin-3-A isoform X1 K03869 CUL3; cullin 3
E 124365536 cullin-3-like K03869 CUL3; cullin 3
E 124360289 cullin-5 K10612 CUL5; cullin 5
E 124365286 elongin-C K03872 ELOC; elongin-C
E 124361716 elongin-B K03873 ELOB; elongin-B
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 124360659 LOW QUALITY PROTEIN: DNA mismatch repair protein Msh2-like K08735 MSH2; DNA mismatch repair protein MSH2
E 124360475 DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 124373863 LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh1-like K08734 MLH1; DNA mismatch repair protein MLH1
E 124363158 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 124373958 LOW QUALITY PROTEIN: mismatch repair endonuclease PMS2-like K10858 PMS2; DNA mismatch repair protein PMS2
E 124353487 mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 124370666 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 124362054 DNA polymerase delta catalytic subunit isoform X1 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 124375133 DNA polymerase delta catalytic subunit-like K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 124355568 DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2
E 124362770 DNA polymerase delta subunit 3-like K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 124364852 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 124367849 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 124371770 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 124362161 replication factor C subunit 1-like K10754 RFC1; replication factor C subunit 1
E 124352789 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E 124367267 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 124367272 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
E 124367994 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
E 124360468 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 124371691 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 124357629 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 124359957 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 124367333 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 124372682 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 124361794 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 124363352 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 124357313 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA1-core complex
E 124362174 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
D BRCA1-A complex
E 124367895 lys-63-specific deubiquitinase BRCC36-like isoform X1 K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D BRCA1-B complex
E 124369044 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D BRCA1-C complex
E 124361794 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 124363352 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 124357313 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D BRCA complex
E 124352752 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 124352752 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 124360554 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 124367731 DNA repair protein RAD51 homolog 4-like K10871 RAD51L3; RAD51-like protein 3
E 124367732 DNA repair protein RAD51 homolog 4-like K10871 RAD51L3; RAD51-like protein 3
E 124356640 DNA repair protein XRCC2-like K10879 XRCC2; DNA-repair protein XRCC2
E 124362628 DNA repair protein XRCC3 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 124363706 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 124359416 LOW QUALITY PROTEIN: DNA repair and recombination protein RAD54B-like K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 124356173 ATP-dependent DNA helicase Q1-like isoform X1 K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 124366257 ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 124360557 ATP-dependent DNA helicase Q5-like K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
E 124374104 ATP-dependent DNA helicase Q5-like K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 124354530 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 124357509 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E 124364852 replication protein A 32 kDa subunit isoform X1 K10739 RFA2; replication factor A2
E 124367849 replication protein A 14 kDa subunit-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 124353677 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 catalytic subunit-like K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 124371210 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 3-like K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E 124356637 serine/threonine-protein phosphatase 4 regulatory subunit 4-like isoform X1 K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
E 124353615 AP-5 complex subunit zeta-1-like isoform X1 K19025 AP5Z1; AP-5 complex subunit zeta-1
D SMC5-SMC6 complex
E 124354821 structural maintenance of chromosomes protein 5 isoform X1 K22803 SMC5; structural maintenance of chromosomes protein 5
E 124355373 LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 124372850 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
D Other HR factors
E 124364286 crossover junction endonuclease EME1 isoform X1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 124360431 crossover junction endonuclease MUS81 isoform X1 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 124365223 flap endonuclease GEN isoform X1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 124366936 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 124366092 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 124368787 uncharacterized protein LOC124368787 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein
E 124359545 heat shock factor 2-binding protein-like isoform X1 K25791 HSF2BP; heat shock factor 2-binding protein
E 124360173 protein MMS22-like isoform X1 K26125 MMS22L; protein MMS22-like
E 124372059 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 124364213 tonsoku-like protein isoform X1 K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 124359712 biorientation of chromosomes in cell division protein 1-like 1 isoform X1 K27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 124358277 X-ray repair cross-complementing protein 6-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 124358278 X-ray repair cross-complementing protein 6-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 124358282 X-ray repair cross-complementing protein 6-like K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 124368786 X-ray repair cross-complementing protein 6-like isoform X1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 124362728 X-ray repair cross-complementing protein 5-like K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E 124361794 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 124363352 double-strand break repair protein MRE11-like K10865 MRE11; double-strand break repair protein MRE11
E 124357313 DNA repair protein RAD50 isoform X1 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 124354811 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E 124353120 DNA polymerase lambda-like K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E 124372526 LOW QUALITY PROTEIN: DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
E 124353086 DNA polymerase beta-like K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E 124354159 aprataxin-like K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 124369086 protein artemis-like K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
E 124372224 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E 124366363 centromere protein S-like isoform X1 K11511 APITD1; centromere protein S
E 124355316 centromere protein X-like isoform X1 K15360 STRA13; centromere protein X
E 124354614 ubiquitin-conjugating enzyme E2 T-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 124354530 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 124357509 DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
E 124375221 Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 124369044 Fanconi anemia group J protein homolog isoform X1 K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E 124354909 fanconi-associated nuclease 1-like K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E 124352752 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 124360554 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 124359058 telomere length regulation protein TEL2 homolog isoform X1 K11137 TELO2; telomere length regulation protein
E 124361887 WD repeat-containing protein 48 isoform X1 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 124360028 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 124368259 serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 124362622 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A-like K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
E 124363149 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C-like K15504 ANKRD52; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
D Ubiquitin ligases
E 124356860 E3 ubiquitin-protein ligase RNF8-like isoform X1 K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
E 124360004 E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 124359330 telomerase Cajal body protein 1-like isoform X1 K23314 WRAP53; telomerase Cajal body protein 1
E 124372682 WD repeat-containing protein 76-like K24755 WDR76; WD repeat-containing protein 76
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 124364740 DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 124352950 DNA polymerase iota-like K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 124352954 DNA polymerase iota-like isoform X1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 124361970 DNA repair protein REV1-like K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
C A-family DNA polymerase
D 124355761 LOW QUALITY PROTEIN: DNA polymerase nu-like K16618 POLN; DNA polymerase nu [EC:2.7.7.7]
C Rad6 epistasis group
D 124360321 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 124362492 E3 ubiquitin-protein ligase RAD18-like K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 124353806 ubiquitin-conjugating enzyme E2 variant 2 isoform X1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 124354871 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 124357629 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 124368067 LOW QUALITY PROTEIN: DNA-dependent metalloprotease SPRTN K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 124357666 uncharacterized protein LOC124357666 K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 124361785 cell cycle checkpoint control protein RAD9A isoform X1 K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 124357140 checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
C HRAD17(Rad24)-RFC complex
D 124352789 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 124367267 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 124367272 replication factor C subunit 2-like K10755 RFC2_4; replication factor C subunit 2/4
D 124367994 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
D 124360468 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 124371691 replication factor C subunit 5-like K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
D 124372903 protein timeless homolog isoform X1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 124355745 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 124355252 uncharacterized protein LOC124355252 K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D 124359058 telomere length regulation protein TEL2 homolog isoform X1 K11137 TELO2; telomere length regulation protein
C BAG6-UBL4A-GET4 complex
D 124365843 ubiquitin-like protein 4A isoform X1 K23388 UBL4; ubiquitin-like protein 4
D 124353899 Golgi to ER traffic protein 4 homolog isoform X1 K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 124360495 serine/threonine-protein kinase ATR-like K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 124362635 serine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 124356593 serine/threonine-protein kinase grp K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 124367730 serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 124367733 serine/threonine-protein kinase Chk2-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 124362126 14-3-3 protein zeta isoform X1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 124369233 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon
D 124360389 protein sickie isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 124368817 plastin-2 K17336 PLS3; plastin-3
D 124362793 vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
D 124361028 helicase POLQ-like isoform X1 K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D 124368055 LOW QUALITY PROTEIN: pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 124359342 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 124370967 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 124370974 pre-mRNA-splicing factor SPF27-like K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 124360448 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 124359317 8-oxo-dGDP phosphatase NUDT18 isoform X1 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 124370431 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124371390 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124372440 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124372690 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124375177 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124355149 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124367424 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124367438 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124356673 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 124353678 ribonucleoside-diphosphate reductase subunit M2 B K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 124371107 LOW QUALITY PROTEIN: deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D 124361862 deoxyribodipyrimidine photo-lyase-like K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 124359334 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 124374971 uracil-DNA glycosylase-like K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E 124352877 single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 124362394 probable DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 124370431 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124371390 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124372440 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124372690 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124375177 deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124355149 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124367424 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 124367438 deoxyuridine 5'-triphosphate nucleotidohydrolase-like isoform X1 K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024