+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Idiomarina loihiensis GSL 199</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
D      Cap binding complex
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
D      Cleavage and polyadenylation specificity factor (CPSF) complex
D      Cleavage stimulation factor (CSTF) complex
D      U7-dependent histone pre-mRNA processing factors
D      DRB sensitivity inducing factor (DSIF) complex
D      N6-methyltransferase complex
D      Poly(A) addition factors
D      Negative regulators of mRNA 3' end processing
C    Other processing factors
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
D      TREX complex
D      TREX-2 complex
D      Nuclear pore complex
D      Ran-mediated transport factors
D      eIF4F and regulatory proteins
D      APOBEC1-ACF complex
D      Other transport factors
C    Surveillance factors
D      Surveillance complex
D      Protein phosphatase 2A
D      Other surveillance factors
C    Factors involved in mRNA localization
D      Cargo complex
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
D      Other mRNA localization factors
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
D      P-body specific factors
D      Stress granule specific factors
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
D      Lsm complex
D      5' exonucleases
D      Other 5'-3' decay factors
C    3'-5' decay
D      Core exosome factors
D      Exosome cofactors
D      TRAMP complex
D      Ski complex
D      Ccr4-NOT complex
D      Pan complex
D      Other 3'-5' decay factors
C    Other degradation factors
D      RNases
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A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        K734_06780 RNase E	K08300 rne; ribonuclease E [EC:3.1.26.12] 
E        K734_01930 ribonuclease G	K08301 rng; ribonuclease G [EC:3.1.26.-] 
E        K734_04070 RNase III, dsRNA-specific ribonuclease	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        K734_09780 exoribonuclease R	K12573 rnr; ribonuclease R [EC:3.1.13.1] 
E        K734_11580 oligoribonuclease	K13288 orn; oligoribonuclease [EC:3.1.-.-] 
D      Helicases
E        K734_11895 ATP-dependent RNA helicase RhlB	K03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7] 
E        K734_07500 ATP-dependent RNA helicase	K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] 
E        K734_07775 ATP-dependent RNA helicase	K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7] 
E        K734_10025 ATP-dependent RNA helicase	K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7] 
E        K734_12815 superfamily II DNA helicase	K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] 
D      Other RNA degradosome components
E        K734_03870 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        K734_04845 polynucleotide phosphorylase/polyadenylase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        K734_11885 rho; transcription termination factor Rho	K03628 rho; transcription termination factor Rho 
E        K734_06090 6-phosphofructokinase	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        K734_04955 molecular chaperone DnaK	K04043 dnaK; molecular chaperone DnaK 
E        K734_11480 molecular chaperone GroEL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
E        K734_01670 host factor I-like protein	K03666 hfq; host factor-I protein 
D      Others
E        K734_10120 polyphosphate kinase	K00937 ppk1; polyphosphate kinase [EC:2.7.4.1] 
E        K734_11340 poly(A) polymerase	K00970 pcnB; poly(A) polymerase [EC:2.7.7.19] 
E        K734_02520 RNA pyrophosphohydrolase	K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-] 
E        K734_08750 carbon storage regulatory protein	K03563 csrA; carbon storage regulator 
E        K734_12355 ribonuclease activity regulator protein RraA	K02553 rraA; regulator of ribonuclease activity A 
E        K734_09825 RNase E inhibitor protein	K09893 rraB; regulator of ribonuclease activity B 
E        K734_01970 glmZ(sRNA)-inactivating NTPase	K06958 rapZ; RNase adapter protein RapZ 
E        K734_06870 helicase, ATP-dependent	K03578 hrpA; ATP-dependent RNA helicase HrpA [EC:5.6.2.6] 
E        K734_11315 helicase, ATP-dependent	K03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6] 
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
D      Cofactors
D      Others
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#Last updated: August 27, 2025