+C Two-component system KO #

  Two-Component System - Janthinobacterium svalbardensis

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AOmpR family B PhoR-PhoB (phosphate starvation response) C CNX70_11385 phoR; phosphate regulon sensor histidine kinase PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] C CNX70_00680 PAS domain-containing sensor histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3] C CNX70_11380 DNA-binding response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB B SenX3-RegX3 (phosphate starvation response) C CNX70_03975 sensor histidine kinase K07768 senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3] B PhoQ-PhoP (magnesium transport) B EnvZ-OmpR (osmotic stress response) C CNX70_20525 two-component sensor histidine kinase K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3] C CNX70_20520 two-component system response regulator OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR B RstB-RstA B CpxA-CpxR (envelope stress response) B CssS-CssR (secretion stress response) B CreC-CreB (phosphate regulation) C CNX70_03230 two-component system sensor histidine kinase CreC K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] C CNX70_03225 two-component system response regulator CreB K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB B BaeS-BaeR (envelope stress response) B BasS-BasR (antimicrobial peptide resistance) B CusS-CusR (copper tolerance) C CNX70_00145 two-component sensor histidine kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3] C CNX70_00150 DNA-binding response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR B QseC-QseB (quorum sensing) C CNX70_14230 two-component sensor histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3] C CNX70_11295 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB C CNX70_14225 DNA-binding response regulator K07666 qseB; two-component system, OmpR family, response regulator QseB B KdpD-KdpE (potassium transport) C CNX70_25710 two-component system sensor histidine kinase KdbD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3] C CNX70_25705 two-component system response regulator KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE B TorS-TorR (TMAO respiration) B ArcB-ArcA (anoxic redox control) B TctE-TctD (tricarboxylic acid transport) C CNX70_22140 sensor histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3] C CNX70_22135 DNA-binding response regulator K07774 tctD; two-component system, OmpR family, response regulator TctD B ResE-ResD (aerobic and anaerobic respiration) B VicK-VicR (cell wall metabolism) B MprB-MprA (maintenance of persistent infection) B MtrB-MtrA (osmotic stress response) B PrrB-PrrA (intracellular multiplication) B TrcS-TrcR B NrsS-NrsR (nickel tolerance) B ManS-ManR (manganese homeostasis) B NblS-NblR (photosynthesis) B SasA-RpaAB (circadian timing mediating) B SaeS-SaeR (staphylococcal virulence regulation) B BceS-BceR (bacitracin transport) B BraS-BraR (bacitracin transport) B GraS-GraR (cationic antimicrobial peptide transport) B YxdK-YxdJ (antimicrobial peptide response) B ChvG-ChvI (acidity sensing) B CiaH-CiaR B ParS-ParR (polymyxin-adaptive resistance) B AdeS-AdeR C CNX70_13980 two-component sensor histidine kinase K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3] C CNX70_13985 DNA-binding response regulator K18144 adeR; two-component system, OmpR family, response regulator AdeR B VanS-VanR (VanB type vancomycin resistance) B VanS-VanR (VanE type vancomycin resistance) B VanS-VanR (actinomycete type vancomycin resistance) B ArlS-ArlR (virulence regulation) B Ihk-Irr (virulence regulation) B PfeS-PfeR (enterobactin-dependent iron acquisition) B NisK-NisR (lantibiotic biosynthesis) B Unclassified C CNX70_22855 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C CNX70_13955 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C CNX70_17670 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C CNX70_24940 two-component sensor histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3] C CNX70_03390 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_00675 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_22860 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_26570 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_16905 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_17665 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_13950 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator C CNX70_24565 DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator # ANarL family B NarX-NarL (nitrate respiration) C CNX70_07750 histidine kinase K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3] C CNX70_14430 transcriptional regulator K07673 narX; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarX [EC:2.7.13.3] C CNX70_07755 DNA-binding response regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL C CNX70_14435 DNA-binding response regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL C CNX70_10310 DNA-binding response regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL C CNX70_22975 DNA-binding response regulator K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL B NarQ-NarP (nitrate respiration) B UhpB-UhpA (hexose phosphates uptake) C CNX70_10515 hypothetical protein K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3] C CNX70_23205 two-component sensor histidine kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3] B FusK-FusR (virulence regulation) C CNX70_04275 two-component sensor histidine kinase K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3] C CNX70_16520 hypothetical protein K20263 fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3] B RcsC-RcsD-RcsB (capsule synthesis) B BarA-UvrY (central carbon metabolism) C CNX70_04270 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY C CNX70_23210 DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY B ComP-ComA (competence) B EvgS-EvgA (acid and drug tolerance) B DegS-DegU (multicellular behavior control) B DesK-DesR (membrane lipid fluidity regulation) B VraS-VraR (cell-wall peptidoglycan synthesis) B LiaS-LiaR (cell wall stress response) B DevS-DevR (redox response) B NreB-NreC (dissimilatory nitrate/nitrite reduction) B YdfH-YdfI B SalK-SalR B PprA–PprB (biofilm formation) B Unclassified C CNX70_09485 histidine kinase K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3] # ASpo family B KinABCDE-Spo0FA (sporulation control) # ACitB family B CitA-CitB (citrate fermentation) B CitS-CitT (magnesium-citrate transport) B DcuS-DcuR (C4-dicarboxylate metabolism) B DctS-DctR (C4-dicarboxylate transport) B MalK-MalR (malate transport) B Unclassified # ALytTR family B LysS-LysR B AlgZ-AlgR (alginate production) C CNX70_11415 sensor histidine kinase K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3] C CNX70_08765 sensor histidine kinase K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3] B NatK-NatR (sodium extrusion) B AgrC-AgrA (exoprotein synthesis) B AgrC2-AgrA2 (virulence regulation) B ComD-ComE (competence) B Unclassified C CNX70_08760 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator C CNX70_11420 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator C CNX70_10185 DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator # ANtrC family B GlnL-GlnG (nitrogen regulation) C CNX70_06505 PAS domain-containing sensor histidine kinase K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3] C CNX70_06510 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG B NtrY-NtrX (nitrogen regulation) C CNX70_04845 PAS domain-containing sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3] C CNX70_04850 two-component system response regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX B HydH-HydG (metal tolerance) B AtoS-AtoC (cPHB biosynthesis) B PilS-PilR (type 4 fimbriae synthesis) C CNX70_25495 sigma-54-dependent Fis family transcriptional regulator K02667 pilR; two-component system, NtrC family, response regulator PilR B GlrK-GlrR (amino sugar metabolism) C CNX70_01290 two-component sensor histidine kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3] C CNX70_01280 two-component system response regulator GlrR K07715 glrR; two-component system, NtrC family, response regulator GlrR B PgtB-PgtA (phosphoglycerate transport) B DctB-DctD (C4-dicarboxylate transport) C CNX70_00220 two-component sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3] C CNX70_00225 Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD C CNX70_10140 Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD B KinB-AlgB (alginate production) B HupT-HupR (hydrogenase synthesis regulation) B Unclassified C CNX70_06520 histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] C CNX70_20280 PAS domain-containing sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] C CNX70_20290 PAS domain-containing sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3] # ACheA family B CheA-CheYBV (chemotaxis) C CNX70_11010 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C CNX70_22400 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] C CNX70_11005 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C CNX70_11040 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C CNX70_08485 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C CNX70_27265 hypothetical protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C CNX70_22955 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY C CNX70_11035 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C CNX70_22520 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] C CNX70_20615 chemotaxis protein CheB K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61] C CNX70_23085 chemotaxis protein CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV B ChpA-ChpB/PilGH (chemosensory) C CNX70_25340 hybrid sensor histidine kinase/response regulator K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator) C CNX70_25360 two-component system response regulator K02657 pilG; twitching motility two-component system response regulator PilG C CNX70_25355 two-component system response regulator K02658 pilH; twitching motility two-component system response regulator PilH B PixL-PixGH (positive phototaxis) B WspE-WspRF (chemosensory) C CNX70_08965 hybrid sensor histidine kinase/response regulator K13490 wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE C CNX70_08955 diguanylate cyclase response regulator K11444 wspR; two-component system, chemotaxis family, response regulator WspR [EC:2.7.7.65] C CNX70_08960 chemotaxis response regulator protein-glutamate methylesterase K13491 wspF; two-component system, chemotaxis family, response regulator WspF [EC:3.1.1.61] B Cph1-Rcp1 (light response) # ACell cycle family B PleC-PleD (cell fate control) B CckA-CtrA/CpdR (cell cycle control) B Hk1-Rrp1 (glycerol uptake and utilization) # ALux family B LuxQN/CqsS-LuxU-LuxO (quorum sensing) C CNX70_23565 two-component sensor histidine kinase K10916 cqsS; two-component system, CAI-1 autoinducer sensor kinase/phosphatase CqsS [EC:2.7.13.3 3.1.3.-] # ALuxR family B DctS-DctR (C4-dicarboxylate transport) C CNX70_24995 PAS domain-containing sensor histidine kinase K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3] C CNX70_25000 DNA-binding response regulator K11712 dctR; two-component system, LuxR family, response regulator DctR B TtrS-TtrR (tetrathionate respiration) C CNX70_03515 sensor histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3] B FixL-FixJ (nitrogen fixation) C CNX70_24555 histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3] B SsrA-SsrB # AOther families B FlrB-FlrC (polar flagellar synthesis) B AauS-AauR (acidic amino acids utilization) B SLN1-YPD1-SSK1/SKN7 (osmosensing) B RpfC-RpfG (cell-to-cell signaling) B GlnK-GlnL (glutamine utilization) B HspS-HspR (hexose phosphates uptake) B YesM-YesN B CikA B RegB-RegA (redox response) C CNX70_16005 histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3] C CNX70_16000 two-component system response regulator K15012 regA; two-component system, response regulator RegA B FitF-FitH (insecticidal toxin regulation) B PhcS-PhcRQ C CNX70_16575 two-component sensor histidine kinase K19621 phcS; two-component system, sensor histidine kinase PhcS [EC:2.7.13.3] C CNX70_16570 hybrid sensor histidine kinase/response regulator K19622 phcR; two-component system, response regulator PhcR C CNX70_16565 hypothetical protein K19623 phcQ; two-component system, probable response regulator PhcQ B SagS-HptB-HsbR (swarming activity and biofilm formation) C CNX70_14455 hybrid sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] C CNX70_17050 hybrid sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] C CNX70_07825 hybrid sensor histidine kinase/response regulator K20974 K20974; two-component system, sensor histidine kinase [EC:2.7.13.3] B PdtaS-PdtaR C CNX70_05165 response regulator K22010 pdtaR; two-component system, response regulator PdtaR B NasS-NasT C CNX70_12885 response regulator K07183 nasT; two-component system, response regulator / RNA-binding antiterminator B Unclassified C CNX70_19680 histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS C CNX70_01235 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C CNX70_01885 multi-sensor hybrid histidine kinase K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C CNX70_09470 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C CNX70_26240 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C CNX70_18245 hybrid sensor histidine kinase/response regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] C CNX70_19140 hypothetical protein K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3] ! #
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#Last updated: December 14, 2023